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https://www.readbyqxmd.com/read/28549147/prevalence-and-concordance-of-cutaneous-beta-human-papillomavirus-infection-at-mucosal-and-cutaneous-sites
#1
Shalaka S Hampras, Dana E Rollison, Anna R Giuliano, Sandrine McKay-Chopin, Lucia Minoni, Karen Sereday, Tarik Gheit, Massimo Tommasino
Background: Cutaneous beta human papillomavirus (HPV) infection across cutaneous and mucosal tissues within individuals has not been examined. Methods: A sub-cohort of men (n=87) participating in the 'HPV infection in men' (HIM) study provided eyebrow hairs, forearm skin swabs, genital skin swabs, oral rinse samples and anal swabs. Beta HPV DNA in the five tissues was detected using a multiplex assay and site-specific beta HPV prevalence was examined. Results: Any beta HPV was most prevalent in genital skin (81...
May 26, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28542114/predictors-of-pouchitis-after-ileal-pouch-anal-anastomosis-in-pediatric-onset-ulcerative-colitis
#2
Firas Rinawi, Amit Assa, Rami Eliakim, Yael Mozer Glassberg, Vered Nachmias Friedler, Yaron Niv, Yoram Rosenbach, Ari Silbermintz, Noam Zevit, Raanan Shamir
OBJECTIVES: Few studies have reported on the incidence and risk factors for pouchitis following colectomy and ileal pouch-anal anastomosis (IPAA) in patients with pediatric-onset ulcerative colitis (UC). We aimed to determine clinical predictors for the development of pouchitis following IPAA in this population. PATIENTS AND METHODS: We performed a retrospective chart review of all pediatric UC cases that were diagnosed at the Schneider Children's Medical Center of Israel between 1981 and 2013 and who underwent colectomy during disease course...
May 24, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28539683/stubborn-rectal-prolapse-in-systemic-sclerosis
#3
Sven Petersen, Alexander Tobisch, Gero Puhl, Ina Kötter, Uwe Wollina
Systemic sclerosis (SSc) is an autoimmune connective tissue disorder. Anorectal involvement might typically cause fecal incontinence and rarely rectal prolapse. Here we report three female patients, who were admitted with a mean history of 10 years suffering from SSc. All patients presented with the initial symptom of anal incontinence, in all cases this was associated with rectal intussusception or rectal prolapse. The three women faced prolapse recurrence, independent of the initial procedure. After surgical removal of the prolapse, the incontinence remained...
2017: Reumatologia
https://www.readbyqxmd.com/read/28534332/-efficacy-comparison-of-robotic-and-laparoscopic-radical-surgery-in-the-treatment-of-middle-low-rectal-cancer
#4
Hairong Zhang, Weitang Yuan, Quanbo Zhou, Xiaoming Gu, Fuqi Wang
OBJECTIVE: To compare the clinical efficacy of robotic and laparoscopic radical surgery in the treatment of middle-low rectal cancers. METHODS: From January 2015 to March 2016, intra-operative and postoperative follow-up data of 30 patients with middle-low rectal cancers who underwent robotic radical resection(robot group) and 32 patients with middle-low rectal cancers who underwent laparoscopic radical resection (laparoscopy group)n in our department were retrospectively collected...
May 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28531922/protective-effect-of-averrhoa-bilimbi-l-fruit-extract-on-ulcerative-colitis-in-wistar-rats-via-regulation-of-inflammatory-mediators-and-cytokines
#5
Jagadish Kumar Suluvoy, Sakthivel K M, Guruvayoorappan C, Berlin Grace V M
Ulcerative Colitis (UC) is a lingering type of Inflammatory Bowel Disease (IBD) which affects the colon mucosa. Ulcerative colitis is majorly associated with oxidative stress and inflammation in colon tissue leading to damage. Averrhoa bilimbi L. fruit is rich in antioxidant phytochemicals including Vitamin C. In the current research, we have evaluated the defence mechanism of Averrhoa bilimbi L. on Ulcerative Colitis (UC). Male wistar rats were treated with Averrhoa bilimbi L. fruit extract (50mg/kg/bwt and 100mg/kg/bwt) and a standard drug Sulfasalazine (100mg/kg/bwt) for 6 consecutive days via intra peritoneally...
May 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28527628/multidisciplinary-clinics-for-colorectal-cancer-care-reduces-treatment-time
#6
Vanessa N Kozak, Alok A Khorana, Sudha Amarnath, Katherine E Glass, Matthew F Kalady
INTRODUCTION: Management of locally advanced and metastatic colorectal cancer (CRC) requires the expertise of multiple specialists. Multidisciplinary clinics (MDCs) are a working model designed to facilitate delivery of coordinated care. The present study evaluated the effects of MDC on the time to treatment (TTT). PATIENTS AND METHODS: Patients with CRC or locally advanced anal cancer who were evaluated at a single-institution MDC from January 2014 to October 2015 were identified from an institutional registry...
April 19, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/28526917/do-we-know-the-outcome-predictors-for-cauda-equine-syndrome-ces-a-retrospective-single-center-analysis-of-60-patients-with-ces-with-a-suggestion-for-a-new-score-to-measure-severity-of-symptoms
#7
Alexander König, Lisa Amelung, Marco Danne, Ullrich Meier, Johannes Lemcke
OBJECTIVE: Despite the awareness and familiarity of almost every medical professional with the cauda equine compression syndrome (CES), risk factors for a poor prognosis of the disease remain elusive. Even the relationship between subsequent outcome and the time elapsed from the time of appearance of symptoms to surgery taking place remain obscure. The aim of our study, therefore, was to analyze a relatively large population of our own patients studied consecutively, to identify outcome predictors for CES and to propose a clinical score for CES symptoms (Berlin CES score)...
May 19, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28522947/clinical-efficacy-of-adalimumab-versus-infliximab-and-the-factors-associated-with-recurrence-or-aggravation-during-treatment-of-anal-fistulas-in-crohn-s-disease
#8
Cheng-Chun Ji, Shota Takano
BACKGROUND/AIMS: Infliximab has proven to be effective in the treatment of perianal fistulas in Crohn's disease (CD) but the efficacy of adalimumab is still unclear. The aim of this study is to assess the clinical efficacy of adalimumab and compare the results with those for infliximab. METHODS: Forty-seven CD patients treated for perianal fistulas with infliximab from September 2005 to December 2010 (n=31), or with adalimumab from November 2010 to May 2012 (n=16), were enrolled in this retrospective study...
April 2017: Intestinal Research
https://www.readbyqxmd.com/read/28521797/multiple-cause-of-death-data-among-people-with-aids-in-italy-a-nationwide-cross-sectional-study
#9
Enrico Grande, Antonella Zucchetto, Barbara Suligoi, Francesco Grippo, Marilena Pappagallo, Saverio Virdone, Laura Camoni, Martina Taborelli, Vincenza Regine, Diego Serraino, Luisa Frova
BACKGROUND: Multiple cause-of-death (MCOD) data allow analyzing the contribution to mortality of conditions reported on the death certificate that are not selected as the underlying cause of death. Using MCOD data, this study aimed to fully describe the cause-specific mortality of people with AIDS (PWA) compared to people without AIDS. METHODS: We conducted a nationwide investigation based on death certificates of 2,515 Italian PWA and 123,224 people without AIDS who had died between 2006 and 2010...
May 18, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28506588/double-balloon-enteroscopy-indications-approaches-diagnostic-and-therapeutic-efficacy-and-safety-early-experience-at-a-single-center
#10
J J E García-Correa, J J Ramírez-García, L F García-Contreras, C Fuentes-Orozco, L Irusteta-Jiménez, L R Michel-Espinoza, A S Carballo Uribe, J A Torres Chávez, A González-Ojeda
INTRODUCTION AND AIMS: Double-balloon enteroscopy has been improving the visualization of the entire intestine for more than a decade. It is a complementary method in the study of intestinal diseases that enables biopsies to be taken and treatments to be administered. Our aim was to describe its main indications, insertion routes, diagnostic/therapeutic efficacy, and complications. MATERIALS AND METHODS: All patients referred to our unit with suspected small bowel pathology were included...
May 12, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/28501251/dysplasia-and-cancer-in-inflammatory-bowel-disease
#11
REVIEW
Lyen C Huang, Amit Merchea
Inflammatory bowel disease is associated with an increased risk of dysplasia and cancer. Improvements in medical management and endoscopic surveillance have reduced these risks. Patients can develop cancer even in the absence of dysplasia or with indefinite or low-grade dysplasia. Most guidelines recommend starting surveillance colonoscopy 6 to 10 years after initial diagnosis with interval surveillance afterward every 1 to 5 years depending on risk and/or individual characteristics. Most patients should undergo total proctocolectomy with end ileostomy or reconstruction with ileal pouch anal anastomosis because segmental and subtotal resections carry a higher risk of metachronous cancers...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28500611/-restorative-proctocolectomy-for-ulcerative-colitis-long-term-functional-results-and-quality-of-life
#12
REVIEW
E Rijcken, N Senninger, R Mennigen
Restorative proctocolectomy with ileo-pouch-anal anastomosis is the standard procedure for ulcerative colitis. It provides complete removal of the diseased colorectum, avoids permanent ileostomy and allows the preservation of continence. Functional results and quality of life after restorative proctocolectomy are of great importance. Patients usually have 5-6 bowel movements per day, and continence is satisfactory in more than 90% of patients. A good pouch function strongly correlates with high quality of life...
May 12, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28495319/clinical-characteristics-and-mortality-in-patients-treated-in-a-multidisciplinary-diabetic-foot-unit
#13
José Antonio Rubio, Sara Jiménez, Julia Álvarez
BACKGROUND AND OBJECTIVE: This study reviews the clinical characteristics of patients with diabetic foot ulcer treated in a Multidisciplinary Diabetic Foot Unit (MDFU) and analyzes the mortality and factors associated with its survival. MATERIAL AND METHODS: Data from all patients who attended the MDFU for the first time for a diabetic foot ulcer during the 2008-2014 period were analized. The patients were followed until their death or until June 30, 2016, for up to 8 years...
May 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28486255/intestinal-barrier-disruption-in-ileal-pouchitis-after-ileal-pouch-anal-anastomosis-in-a-rat-model
#14
Kai-Yu Li, Jian-Lin Wang, Yan-Yan Xu, Sen-Yang Gao, Ying-Ying Zhang, An-Qi He, Gang Liu
BACKGROUND: Pouchitis occurs in approximately 50% of patients with ulcerative colitis after ileal pouch-anal anastomosis (IPAA) but the pathogenesis remains unclear. We used a rat model of dextran sulfate sodium (DSS)-induced ileal pouchitis to examine whether intestinal barrier disruption plays a role in the development and progression of the disease. METHODS: Rats were randomly divided into DSS (underwent IPAA and administered 5% DSS orally), IPAA (underwent IPAA), and Sham groups (underwent switch abdominal surgery)...
May 5, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28485812/epidemiology-of-human-papillomavirus-on-anogenital-warts-in-portugal-the-hercoles-study
#15
J Azevedo, A Pista, C Lisboa, I Santo, L Azevedo, M J Cunhax
BACKGROUND: Anogenital warts (AGW) are one of the most prevalent sexually transmitted disease worldwide. Approximately 90% of AGWs are related to infection by HPV 6 and 11. However, AGW have been associated with infection by multiple genotypes, including HR-HPV, which may be associated with a long-term increased risk of anogenital cancer. OBJECTIVE: This observational prospective epidemiological study aims to estimate the type-specific HPV distribution on incident AGWs in both genders, and additionally to assess the frequency of anal and oral HPV infection in patients with AGWs...
May 9, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28480075/concurrent-chemoradiation-with-volumetric-modulated-arc-therapy-of-patients-treated-for-anal-cancer-acute-toxicity-and-treatment-outcome
#16
Kaloyan Yordanov, Simona Cima, Antonella Richetti, Gianfranco Pesce, Francesco Martucci, Ngwa Che Azinwi, Maria Carla Valli
BACKGROUND: to report the acute toxicity and clinical results in patients with anal cancer treated with volumetric modulated arc therapy (VMAT) concomitant with chemotherapy. METHODS: A cohort of 21 patients with histologically confirmed squamous cell carcinoma of the anal canal was treated with VMAT and chemotherapy. Dose prescription was 39.6 Gy, 1.8 Gy/ fraction for the elective nodal PTV, the macroscopic (tumor and involved lymph nodes) PTV doses were 14.4 Gy up to a total dose of 54 Gy in 4 patients and 19...
April 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28473937/herpes-simplex-proctitis-mimicking-inflammatory-bowel-disease-in-a-teenaged-male
#17
Kristen E Sandgren, Nathan B Price, Warren P Bishop, Patrick J McCarthy
We report the case of a 17-year-old male who was initially assessed for pain with defecation, bloody rectal discharge, and diarrhea, consistent with proctitis. Though proctitis is most commonly due to inflammatory bowel disease (IBD), infectious etiologies must also be considered, including sexually transmitted causes of infectious proctitis. In discussion of his sexual history, he identified as homosexual and acknowledged engaging in receptive anal intercourse. Rectal biopsies obtained via colonoscopy were culture-positive for herpes simplex virus (HSV), leading to a diagnosis of HSV proctitis and treatment with an appropriate antiviral medication...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28471820/prevalence-of-intestinal-complications-in-inflammatory-bowel-disease-a-comparison-between-paediatric-onset-and-adult-onset-patients
#18
Denise Herzog, Nicolas Fournier, Patrick Buehr, Vanessa Rueger, Rebekka Koller, Klaas Heyland, Andreas Nydegger, Christian P Braegger
INTRODUCTION: Intestinal complications in inflammatory bowel disease indicate active inflammation and typically result in the intensification of therapy. AIM: To analyse whether the rates of intestinal complications were associated with age at disease onset. PATIENTS AND METHODS: Data from 1506 individuals with Crohn's disease (CD) and 1201 individuals with ulcerative colitis (UC) were obtained from the Swiss inflammatory bowel disease cohort study database, classified into groups on the basis of age at diagnosis (<10, <17, <40 and >40 years of age), and retrospectively analysed...
May 3, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28462237/endoscopic-fistulotomy-heals-a-y-shaped-entero-entero-cutaneous-fistula
#19
Helen Lee, Bo Shen
Patients may develop fistulas due to Crohn's disease or as a postoperative complication after restorative proctocolectomy with ileal pouch anal anastomosis. Unfortunately, the treatment of fistulas can be challenging. The current standard of care may include medical therapy and/or surgical intervention. However, endoscopic treatment for postoperative pouch complications has emerged as a valid alternative option. We describe a case of persistent drainage from a Y-shaped entero-entero-cutaneous fistula that resolved after endoscopic fistulotomy with needle knife...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28456472/a-review-of-risk-behaviors-for-hiv-infection-by-men-who-have-sex-with-men-through-geosocial-networking-phone-apps
#20
Artur Acelino Francisco Luz Nunes Queiroz, Álvaro Francisco Lopes de Sousa, Telma Maria Evangelista de Araújo, Francisco Braz Milanez de Oliveira, Maria Eliete Batista Moura, Renata Karina Reis
The purpose of our review was to analyze the relationship between the use of geosocial networking phone apps and risk behaviors for HIV infection in men who have sex with men (MSM). The review was guided by the question: Does the use of geosocial networking apps to find sex partners increase risk behaviors for HIV infection by MSM? We searched the databases PubMed, Web of Science, CINAHL, and LILACS, considering primary studies published up to December 2015, without any time restraint. All 14 studies that met our search criteria analyzed sexual behaviors in relation to sociocultural and economic characteristics, number of partners, unprotected anal sex, drug use, HIV testing, risk management measures, and the presence of other sexually transmitted diseases...
April 4, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
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