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https://www.readbyqxmd.com/read/28324238/kinetics-of-expression-of-genes-involved-in-glucose-metabolism-after-the-last-meal-in-overfed-mule-ducks
#1
Tavernier Annabelle, Ricaud Karine, Bernadet Marie-Dominique, Davail Stéphane, Gontier Karine
In waterfowls, overfeeding leads to a hepatic steatosis, also called "foie gras." We decided to investigate the role of glucose metabolism in steatosis emergence. For this, we measured the expression of genes during the 12 h following the last meal of the overfeeding period. As expected, it showed that the expression of glucose transporter is more precocious in jejunal mucosa, especially for SGLT1, known to be the major transporter at the apical surface. In the liver, GLUT2 and HK1 are upregulated at the same time and seem to work together to import glucose...
March 21, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28323947/effects-of-mixed-carotenoids-on-adipokines-and-abdominal-adiposity-in-children-a-pilot-study
#2
J Atilio Canas, Amanda Lochrie, Amy Galena McGowan, Jobayer Hossain, Christopher Schettino, P Babu Balagopal
Context: Carotenoids have been implicated in the regulation of adipocyte metabolism. Objective: To compare the effects of mixed-carotenoid supplementation (MCS) vs. placebo on adipokines and the accrual of abdominal adiposity in children with obesity. Design and Setting: Randomized (1:1) double-blind, placebo-controlled intervention trial to evaluate the effects of MCS over 6 months in a subspecialty clinic. Participants: Twenty (6 male and 14 female) children with simple obesity (BMI > 90%); age: 10...
March 13, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323443/impact-of-abdominal-adipose-depots-and-race-on-risk-for-colorectal-cancer-a-case-control-study
#3
Sandra L Gomez-Perez, Vivek Chaudhry, Winnie Mar, Bimal Patel, Giamila Fantuzzi, Sally Freels, Carol A Braunschweig
Visceral adipose tissue (VAT) but not subcutaneous adipose tissue (SAT) is associated with obesity-related diseases including colorectal cancer (CRC). Superficial SAT (SSAT) and deep SAT (DSAT), components of SAT, also appear to independently influence disease risk. These abdominal adipose tissues (AATs) are not extensively studied in connection with CRC and have not been explored in the United States despite known racial variations in body composition. We conducted a case-control study that compared associations between AAT with CRC risk and race of African-American (AA) and non-Hispanic white (NHW) men with incident CRC matched by age, body mass index, and race (N = 158, 79/group)...
March 21, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28317037/the-role-of-familismo-and-acculturation-as-moderators-of-the-association-between-family-conflict-and-substance-abuse-on-latino-adult-males
#4
Roberto Lopez-Tamayo, Alexa Seda, Leonard A Jason
The significant research gap on Latino adults who completed substance abuse treatment (SAT) impacts the provision of substance use prevention and treatment for this population. Given the need for culturally-appropriate SAT for Latinos, research that examines the role of cultural constructs and acculturation in relation to substance use behavior is warranted. The purpose of the present study is to test, based on the social control theory, a multiple moderation model using the PROCESS macro(1) to examine the moderating effect of Familismo on the association between history of family conflict and years of substance abuse on Latino males who completed SAT at different levels of acculturation (i...
August 2016: Public Health (Fairfax)
https://www.readbyqxmd.com/read/28300680/evaluation-by-mri-of-silent-brain-infarcts-in-pre-and-post-operative-asymptomatic-carotid-surgery
#5
Remy Pascot, Anne Daoudal, Alain Cardon, Gilles Godet, Antoine Lucas, Elodie Clochard, Jean-Yves Gauvrit, Yann Le Teurnier, Adrien Kaladji
OBJECTIVE: To report the prevalence of Silent Brain Infarcts (SBI) at MRI before and after surgery for asymptomatic high grade carotid stenosis. DESIGN: Single-center retrospective observational study METHODS: Asymptomatic patients who underwent carotid endarterectomy between October 2012 and October 2014 were included. The preoperative assessment included a Doppler and a CT scan dating less than 3 months. A neurological examination was performed during the anesthesia consultation and in the 15 days before surgery...
March 11, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28298597/sat2-foot-and-mouth-disease-virus-fmdv-structurally-modified-for-increased-thermostability
#6
Katherine A Scott, Abhay Kotecha, Julian Seago, Jingshan Ren, Elizabeth E Fry, David I Stuart, Bryan Charleston, Francois F Maree
Foot-and-mouth disease virus (FMDV) is notoriously unstable, particularly the O and SAT serotypes. Consequently, vaccines derived from heat-labile SAT viruses have been linked to the induction of poor duration immunity and hence require more frequent vaccinations to ensure protection. In-silico calculations predicted residue substitutions that would increase interactions at the inter-pentameric interface supporting increased stability. We assessed the stability of the 18 recombinant mutant viruses for their growth kinetics; antigenicity; plaque morphology; genetic stability; temperature, ionic and pH stability using the thermofluor and inactivation assays, in order to evaluate potential SAT2 vaccine candidates with improved stability...
March 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28296186/changes-in-periprostatic-adipose-tissue-induced-by-5%C3%AE-reductase-inhibitors
#7
D Taussky, M Barkati, S Campeau, K Zerouali, A Nadiri, F Saad, G Delouya
There is increasing interest in periprostatic fat and its influence on prostate cancer aggressiveness. In vitro data suggest that adipose stromal/stem cells (ASCs) can increase production of cytokines and growth factors resulting in invasive growth and metastasis in prostate cancer. The objective of the study was to determine the interaction between 5α-reductase inhibitors (5ARIs) and periprostatic adipose tissue (PPAT) and factors of prostate cancer aggressiveness. In this retrospective study, we identified 61 patients treated with 5ARIs for a period of ≥12 months before undergoing radiation therapy (brachytherapy or external beam radiotherapy)...
March 10, 2017: Andrology
https://www.readbyqxmd.com/read/28294471/ultra-brief-behavioral-skills-trainings-for-blood-injection-injury-phobia
#8
Alicia E Meuret, Erica Simon, Lavanya Bhaskara, Thomas Ritz
BACKGROUND: Blood injection injury (BII) phobia is common, with debilitating consequences to the health and well being of many of its sufferers. BII phobia presents with a unique fear response that can involve drops in blood pressure and ultimately fainting. The aim of this study was to provide proof of concept for a line of brief, easy to implement, video-based interventions for reducing phobic avoidance and fears in BII sufferers. One of the interventions was a novel Hypoventilation Respiratory Training (HRT) aimed at reducing the exaggerated ventilation response (hyperventilation) seen in BII phobia...
March 15, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28288896/age-and-menopause-related-differences-in-subcutaneous-adipose-tissue-estrogen-receptor-mrna-expression
#9
Young-Min Park, Christopher Erickson, Dan Bessesen, Rachael E Van Pelt, Kimberly Cox-York
OBJECTIVES: Changes in estrogen receptor (ER) expression likely underlie differential metabolic effects of estrogen in pre- and postmenopausal women. The aim of the current study was to determine whether ER gene expression in abdominal and femoral subcutaneous adipose tissue (SAT) was associated with age, menopause, or regional adiposity. METHODS: We studied pre- and post-menopausal (n=23 and 22, respectively; age 35-65 y) normal weight (mean±SD; BMI 23.7±2.5 kg/m(2)) women with similar total fat mass...
March 10, 2017: Steroids
https://www.readbyqxmd.com/read/28287121/tool-use-for-corpse-cleaning-in-chimpanzees
#10
Edwin J C van Leeuwen, Katherine A Cronin, Daniel B M Haun
For the first time, chimpanzees have been observed using tools to clean the corpse of a deceased group member. A female chimpanzee sat down at the dead body of a young male, selected a firm stem of grass, and started to intently remove debris from his teeth. This report contributes novel behaviour to the chimpanzee's ethogram, and highlights how crucial information for reconstructing the evolutionary origins of human mortuary practices may be missed by refraining from developing adequate observation techniques to capture non-human animals' death responses...
March 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28287045/promoting-supported-ambulation-in-persons-with-advanced-alzheimer-s-disease-a-pilot-study
#11
Giulio E Lancioni, Nirbhay N Singh, Mark F O'Reilly, Jeff Sigafoos, Fiora D'Amico, Katia Pinto, Floriana De Vanna, Alessandro O Caffò
PURPOSE: This study assessed the effects of an intervention program, which combined the use of a walker with assistive technology, on the ambulation and indices of positive involvement of persons with advanced Alzheimer's disease. A social validation assessment of the program was also carried out. METHOD: The study included 10 participants with moderate to severe Alzheimer's disease and inability to walk independently. During baseline, the participants sat in their chair or were provided with a walker...
March 12, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28281771/an-evaluation-of-serological-tests-in-the-diagnosis-of-bovine-brucellosis-in-naturally-infected-cattle-in-kwazulu-natal-province-in-south-africa
#12
Songelwayo L Chisi, Yoanda Marageni, Prebashni Naidoo, Gloria Zulu, George W Akol, Henriette Van Heerden
The diagnostic sensitivity (DSe) of the Rose Bengal test (RBT), the complement fixation test (CFT), the serum agglutination test (SAT), the competitive enzyme-linked immunosorbent assay (cELISA) and the indirect ELISA (iELISA) were determined in naturally infected cattle in KwaZulu-Natal province of South Africa with known infectious status from culture (gold standard). Natural brucellosis infection status of animals was determined by culturing and identification of Brucella abortus biovar 1 from abomasal fluid, milk, hygroma fluid, lymph nodes or uterine discharges samples...
February 28, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/28281759/application-of-the-transpiration-method-to-determine-the-vapor-pressure-and-related-physico-chemical-data-of-low-volatile-thermolabile-and-toxic-organo-thio-phosphates
#13
Marc A Althoff, Kathrin Grieger, Martin A C Härtel, Konstantin L Karaghiosoff, Thomas M Klapötke, Manfred Metzulat
The present work represents the most recent study on the physico-chemical properties of the organophosphate compound class being directly related to the Chemical Weapons Convention (CWC). This compound class is of great importance in the ongoing conflict in Syria. Here, the vapor pressure of the deadly organo(thio)phosphate Amiton and seven of its derivatives was investigated. These medium to low volatile analytes pose a potential threat toward human life by inhalation or direct contact with the skin at very low doses...
March 22, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28281431/the-accuracy-of-nurse-performance-of-the-triage-process-in-a-tertiary-hospital-emergency-department-in-gauteng-province-south-africa
#14
L N Goldstein, L M Morrow, T A Sallie, K Gathoo, K Alli, T M M Mothopeng, F Samodien
BACKGROUND: Triage in the emergency department (ED) is necessary to prioritise management according to the severity of a patient's condition.The South African Triage Scale (SATS) is a hospital-based triage tool that has been adopted by numerous EDs countrywide.Many factors can influence the outcome of a patient's triage result, and evaluation of performance is therefore pivotal. OBJECTIVES: To determine how often patients were allocated to the correct triage category and the extent to which they were incorrectly promoted or demoted, and to determine the main reasons for errors in a nurse-led triage system...
February 27, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28279659/intensive-early-rehabilitation-in-the-intensive-care-unit-for-liver-transplant-recipients-a-randomised-controlled-trial
#15
Pierre Maffei, Sandrine Wiramus, Laurent Bensoussan, Laurence Bienvenu, Eric Haddad, Sophie Morange, Mohamed Fathallah, Jean Hardwigsen, Jean-Michel Viton, Y Patrice Le Treut, Jacques Albanese, Emilie Gregoire
OBJECTIVE: To validate the feasibility and tolerance of an intensive rehabilitation protocol initiated during the postoperative period in Intensive Care Unit (ICU) in liver transplant recipients. DESIGN: Prospective randomized study SETTING: Intensive Care Unit Post Liver Transplantation PARTICIPANTS: and Interventions: This study compared two groups of liver transplant recipients over a period of one year: the control group (n=20) benefited from the usual treatment applied in the ICU (based on physician prescription for the physiotherapist and applied once a day), while the experimental group (n=20) followed a protocol of early and intensive rehabilitation (based on a written protocol validated by physicians and an evaluation by physiotherapist, with two sessions a day)...
March 6, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28278254/characterizing-the-community-use-of-an-ultralight-wheelchair-with-on-the-fly-adjustable-seating-functions-a-pilot-study
#16
Johanne Mattie, Jaimie Borisoff, William C Miller, Borna Noureddin
An ultralight manual wheelchair that allows users to independently adjust rear seat height and backrest angle during normal everyday usage was recently commercialized. Prior research has been performed on wheelchair tilt, recline, and seat elevation use in the community, however no such research has been done on this new class of manual ultralight wheelchair with "on the fly" adjustments. The objective of this pilot study was to investigate and characterize the use of the two adjustable seating functions available on the Elevation™ ultralight dynamic wheelchair during its use in the community...
2017: PloS One
https://www.readbyqxmd.com/read/28275833/survey-of-emergency-and-essential-surgical-obstetric-and-anaesthetic-services-available-in-bangladeshi-government-health-facilities
#17
Jonathan Loveday, Sonal P Sachdev, Meena N Cherian, Francisco Katayama, A K M Akhtaruzzaman, Joe Thomas, N Huda, E Brian Faragher, Walter D Johnson
OBJECTIVE: Evaluate the capacity of government-run hospitals in Bangladesh to provide emergency and essential surgical, obstetric and anaesthetic services. METHODS: Cross-sectional survey of 240 Bangladeshi Government healthcare facilities using the World Health Organisation Situational Analysis Tool to Assess Emergency and Essential Surgical Care (SAT). This tool evaluates the ability of a healthcare facility to provide basic surgical, obstetric and anaesthetic care based on 108 queries that detail the infrastructure and population demographics, human resources, surgical interventions and reason for referral, and available surgical equipment and supplies...
March 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28273496/ertl-and-non-ertl-amputees-exhibit-functional-biomechanical-differences-during-the-sit-to-stand-task
#18
Abbie E Ferris, Cory L Christiansen, Gary D Heise, David Hahn, Jeremy D Smith
BACKGROUND: People with transtibial amputation stand ~50times/day. There are two general approaches to transtibial amputation: 1) distal tibia and fibula union using a "bone-bridge" (Ertl), 2) non-union of the tibia and fibula (Non-Ertl). The Ertl technique may improve functional outcomes by increasing the end-bearing ability of the residual limb. We hypothesized individuals with an Ertl would perform a five-time sit-to-stand task faster through greater involvement/end-bearing of the affected limb...
February 22, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28270254/consistent-patterns-of-trophic-niche-specialization-in-host-populations-infected-with-a-non-native-copepod-parasite
#19
J Pegg, D Andreou, C F Williams, J R Britton
Populations of generalist species often comprise of smaller sub-sets of relatively specialized individuals whose niches comprise small sub-sets of the overall population niche. Here, the role of parasite infections in trophic niche specialization was tested using five wild fish populations infected with the non-native parasite Ergasilus briani, a copepod parasite with a direct lifecycle that infects the gill tissues of fish hosts. Infected and uninfected fishes were sampled from the same habitats during sampling events...
March 8, 2017: Parasitology
https://www.readbyqxmd.com/read/28269271/powering-and-communication-for-omni-a-distributed-and-modular-closed-loop-neuromodulation-device
#20
Ali Moin, George Alexandrov, Benjamin C Johnson, Igor Izyumin, Fred Burghardt, Kedar Shah, Sat Pannu, Elad Alon, Rikky Muller, Jan M Rabaey
A distributed, modular, intelligent, and efficient neuromodulation device, called OMNI, is presented. It supports closed-loop recording and stimulation on 256 channels from up to 4 physically distinct neuromodulation modules placed in any configuration around the brain, hence offering the capability of addressing neural disorders that are presented at the network level. The specific focus of this paper is the communication and power distribution network that enables the modular and distributed nature of the device...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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