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https://www.readbyqxmd.com/read/29338526/associations-of-abdominal-subcutaneous-and-visceral-fat-with-insulin-resistance-and-secretion-differ-between-men-and-women-the-netherlands-epidemiology-of-obesity-study
#1
Renée de Mutsert, Karin Gast, Ralph Widya, Eelco de Koning, Ingrid Jazet, Hildo Lamb, Saskia le Cessie, Albert de Roos, Jan Smit, Frits Rosendaal, Martin den Heijer
BACKGROUND: Abdominal obesity is a well-established risk factor for the development of type 2 diabetes. However, sex differences may exist. We aimed to investigate the associations of abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) with insulin resistance and insulin secretion in men and women. METHODS: In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study, fasting and postprandial concentrations of glucose and insulin were measured and abdominal fat depots were assessed using magnetic resonance imaging in 2253 participants (53% women)...
January 17, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29338002/the-associations-between-adult-body-composition-and-abdominal-adiposity-outcomes-and-relative-weight-gain-and-linear-growth-from-birth-to-age-22-in-the-birth-to-twenty-plus-cohort-south-africa
#2
Alessandra Prioreschi, Richard J Munthali, Juliana Kagura, Rihlat Said-Mohamed, Emanuella De Lucia Rolfe, Lisa K Micklesfield, Shane A Norris
BACKGROUND: The growing prevalence of overweight and obesity in low- or middle-income countries precipitates the need to examine early life predictors of adiposity. OBJECTIVES: To examine growth trajectories from birth, and associations with adult body composition in the Birth to Twenty Plus Cohort, Soweto, South Africa. METHODS: Complete data at year 22 was available for 1088 participants (536 males and 537 females). Conditional weight and height indices were generated indicative of relative rate of growth between years 0-2, 2-5, 5-8, 8-18, and 18-22...
2018: PloS One
https://www.readbyqxmd.com/read/29337272/circulating-adipokines-and-mrna-expression-in-adipose-tissue-and-the-placenta-in-women-with-gestational-diabetes-mellitus
#3
Panayoula C Tsiotra, Panagiotis Halvatsiotis, Konstantinos Patsouras, Eirini Maratou, George Salamalekis, Sotirios A Raptis, George Dimitriadis, Eleni Boutati
Maternal adipose tissue and the placenta secrete various molecules commonly called adipokines such as chemerin, omentin-1, visfatin, adiponectin, and leptin that are important players in the pathogenesis of insulin resistance. Gestational diabetes mellitus (GDM) is defined as a state of glucose intolerance characterized by β-cell dysfunction and insulin resistance. To examine whether circulating adipokines and their mRNA expression in the adipose tissue and the placenta are altered in GDM pregnancy, we compared 15 GDM women [obese (BMI > 30) and non-obese (BMI < 30)] to 23 NGT (normal glucose tolerance) women [obese and non-obese], at the time of the Cesarean section...
January 11, 2018: Peptides
https://www.readbyqxmd.com/read/29335416/lack-of-pronounced-changes-in-the-expression-of-fatty-acid-handling-proteins-in-adipose-tissue-and-plasma%C3%A2-of-morbidly-obese-humans
#4
Ewa Anna Grzegorczyk, Ewa Harasim-Symbor, Bartlomiej Lukaszuk, Dorota Harasiuk, Barbara Choromanska, Piotr Mysliwiec, Malgorzata Zendzian-Piotrowska, Adrian Chabowski
BACKGROUND/OBJECTIVES: Fatty acid handling proteins are involved in the process of accumulation of lipids in different fat tissue depots. Thus, the aim of the study was to estimate the expression of both fatty acid transport and binding proteins in the subcutaneous (SAT) and visceral adipose tissue (VAT) of patients with morbid obesity without metabolic syndrome, as well as the plasma concentrations of these transporters. SUBJECTS/METHODS: Protein (Western blotting) and mRNA (Real-time PCR) expression of selected fatty acid handling proteins was assessed in the visceral and subcutaneous adipose tissue of 30 patients with morbid obesity...
January 15, 2018: Nutrition & Diabetes
https://www.readbyqxmd.com/read/29329105/daily-sitting-time-associated-with-the-risk-of-metabolic-syndrome-in-korean-adolescents
#5
Ki Nam Bae, Hye Ryun Kim, Young-Jun Rhie, Kee-Hyoung Lee, Hyo-Kyoung Nam
BACKGROUND: This study aimed to investigate the relationship between daily sitting time and the risk of metabolic syndrome in Korean adolescents. METHODS: Data from 486 adolescents aged 12-18 years were obtained from national surveys. Daily sitting time was measured using questionnaires and divided into three intervals: <8 h; 8-12 h; and ≥12 h. RESULTS: The mean daily sitting time and prevalence of positive metabolic components were 620...
January 12, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29329053/long-term-safety-area-tracking-lt-sat-with-online-failure-detection-and-recovery-for-robotic-minimally-invasive-surgery
#6
Veronica Penza, Xiaofei Du, Danail Stoyanov, Antonello Forgione, Leonardo S Mattos, Elena De Momi
Despite the benefits introduced by robotic systems in abdominal Minimally Invasive Surgery (MIS), major complications can still affect the outcome of the procedure, such as intra-operative bleeding. One of the causes is attributed to accidental damages to arteries or veins by the surgical tools, and some of the possible risk factors are related to the lack of sub-surface visibilty. Assistive tools guiding the surgical gestures to prevent these kind of injuries would represent a relevant step towards safer clinical procedures...
December 22, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/29324430/a-prospective-multicenter-study-to-compare-a-disposable-high-fluid-capacity-underpad-to-nonpermeable-disposable-reusable-containment-products-on-incontinence-associated-dermatitis-rates-among-skilled-nursing-facility-residents
#7
Glenda Motta, Catherine T Milne
Due to the high prevalence of incontinence among skilled nursing facility (SNF) residents, incontinence-associated derma- titis (IAD) is a common occurrence. In addition, facility staff may mistakenly identify IAD as a pressure injury. A prospective, descriptive, multicenter study was conducted in 3 Connecticut facilities to evaluate the effect of substituting a disposable, high- uid capacity underpad for nonpermeable disposable and reusable containment products on the rate of IADs. Residents with and without IAD but with high IAD risk scores who were bed- or chairbound or ambulatory and used disposable nonpermeable briefs and underpads or reusable, laundered containment products when in bed longer than 2 hours were randomly enrolled and observed for a 4-week period...
December 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/29321474/magnetisation-process-in-the-rare-earth-tetraborides-ndb4-and-hob4
#8
D Brunt, G Balakrishnan, D A Mayoh, M R Lees, D Gorbunov, N Qureshi, O A Petrenko
A field-induced magnetisation process in the frustrated antiferromagnets is often much richer compared to the materials without competing interactions. The applied field tends to stabilise unusual spin configurations which frequently results in the appearance of magnetisation plateaux. Here we report a study into the field-induced magnetisation of the two frustrated rare earth tetraborides, HoB4 and NdB4. NdB4 shows a fractional magnetisation plateau occurring at M/M sat ≈ [Formula: see text] before saturating in a field of 33 kOe...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29315620/amyloid-goiter-mimicking-subacute-thyroiditis-on-clinical-and-imaging-findings-a-case-report
#9
Yoo Jin Lee, Soo Jin Jung, Dong Wook Kim, Hwa Jin Cho, Ki Jung Ahn
Amyloid goiter (AG) is defined as the diffuse enlargement of the thyroid gland resulting from extensive amyloid deposition. Imaging findings in AG may vary depending on the amount of amyloid and fat deposition. A few case reports of AG with clinically subacute thyroiditis (SAT)-like syndrome have been published. However, there have been no reports on AG mimicking SAT with clinical and imaging findings. Herein, we present a case of AG mimicking SAT with a detailed report of the clinical and imaging findings.
January 8, 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29313270/ultrasound-elastography-based-assessment-of-the-elasticity-of-the-supraspinatus-muscle-in-impingement-syndrome-does-elastography-has-any-diagnostic-value
#10
Adnan Demirel, Murat Baykara, Tuba Tülay Koca, Ejder Berk
Ultrasound elastography (UE) is a new ultrasound-based imaging technique that provides information about elasticity and stiffness of tissues. This cross-sectional study aimed to identify the diagnostic importance of UE in supraspinatus impingement syndrome. Forty-one subjects, aged 38-70 years, were included in the study. UE was used to determine the elasticity of the supraspinatus muscle. The strain ratio was calculated as the evaluation criteria to measure the elasticity of the muscle. High strain ratio indicated low elasticity...
January 8, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29311699/scientific-aptitude-better-explains-poor-responses-to-teaching-of-evolution-than-psychological-conflicts
#11
Rebecca Mead, Momna Hejmadi, Laurence D Hurst
It is considered a myth that non-acceptance of scientific consensus on emotive topics is owing to difficulties processing scientific information and is, instead, owing to belief-associated psychological conflicts, the strongest non-acceptors being highly educated. It has been unclear whether these results from adults explain variation in response to school-level teaching. We studied a cohort of UK secondary school students (aged 14-16) and assessed their acceptance and understanding of evolution. In addition, to address their aptitude for science we assessed their understanding of genetics and their teacher-derived assessment of science aptitude...
January 8, 2018: Nature Ecology & Evolution
https://www.readbyqxmd.com/read/29310845/serological-study-of-brucellosis-in-argentine-creole-sheep
#12
Gustavo E López, Sabrina Peña, Gabriela I Escobar, Déborah B Hasan, Nidia E Lucero
Ovine cattle was introduced into America during the Spanish conquest with the second journey of Columbus to the Antilles and was disseminated throughout the region. In 1587, sheep were introduced into Argentina, later developing into the "Creole" breed. We selected 486 animals from different Argentine provinces with the aim of determining the serological status of brucellosis caused by Brucella melitensis and Brucella ovis. For the detection of antibodies against smooth Brucella spp., the Rose Bengal test (RBT) was performed as screening test while the serum agglutination test (SAT) and 2 mercapto-ethanol (2ME) were run as a confirmatory technique...
January 5, 2018: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29310638/the-use-of-an-alternate-side-lying-positioning-strategy-during-inhalation-therapy-does-not-prolong-nebulisation-time-in-adults-with-cystic-fibrosis-a-randomised-crossover-trial
#13
Ruth L Dentice, Mark R Elkins, Genevieve M Dwyer, Peter T P Bye
BACKGROUND: Inhalation of nebulised medications is performed in upright sitting to maximise lung volumes. The pattern of deposition is poor for inhaled medications in people with Cystic Fibrosis. The pattern tends to be non-uniform and typically the upper lobes receive a reduced dose compared to the rest of the lung. One strategy that has been proposed as having the potential to improve homogeneity of deposition is to adopt an alternate side lying position for the inhalation procedure...
January 8, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29305450/in-vivo-three-dimensional-kinematics-of-normal-knees-during-different-high-flexion-activities
#14
K Kono, T Tomita, K Futai, T Yamazaki, S Tanaka, H Yoshikawa, K Sugamoto
AIMS: In Asia and the Middle-East, people often flex their knees deeply in order to perform activities of daily living. The purpose of this study was to investigate the 3D kinematics of normal knees during high-flexion activities. Our hypothesis was that the femorotibial rotation, varus-valgus angle, translations, and kinematic pathway of normal knees during high-flexion activities, varied according to activity. MATERIALS AND METHODS: We investigated the in vivo kinematics of eight normal knees in four male volunteers (mean age 41...
January 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29299224/the-effectiveness-of-functional-electrical-stimulation-fes-in-on-off-mode-for-enhancing-the-cycling-performance-of-team-phoenix-at-2016-cybathlon
#15
Kenry Wc Leung, Raymond Ky Tong, Xiaojun Wang, Ginny Ty Lee, Peter Mk Pang, H W Wai, H C Leung
In this study we designed a Functional Electrical Stimulation (FES) trike for a female subject with spinal cord injury to exercise her lower limbs and improve her lower limb muscle condition for attending the 2016 Cybathlon FES bike competition. Our FES pilot was the only female participant, in the FES cycling competition and she rode for Team Phoenix from the Chinese University of Hong Kong. Due to the weakness of muscles in the lower limb of the subject, and due to scoliosis over her thoracolumbar aéra, the mechanical structure of the trike had to be tailor-made to ensure she sat on the bike in a safe and secure position...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29298470/translation-and-linguistic-validation-of-the-korean-version-of-the-treatment-satisfaction-visual-analogue-scale-and-the-overactive-bladder-satisfaction-with-treatment-questionnaire
#16
Ha Na Lee, Ji Yun Chae, Hyo Serk Lee, Min Soo Choo, Min Gu Park, Seo Yeon Lee, Seung-June Oh, Sung Yong Cho
PURPOSE: This study reports the development of the Korean Version of the Treatment Satisfaction Visual Analogue Scale (TS-VAS) and the Overactive Bladder Satisfaction with Treatment Questionnaire (OAB-SAT-q) based on the original versions, with subsequent linguistic validation by Korean patients with overactive bladder receiving active treatment from a physician. METHODS: Translation and linguistic validation were performed in 2016. The validation process included permission for translation, forward translation, reconciliation, backward translation, cognitive debriefing, and proofreading...
December 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/29286536/optimal-remediation-scheme-for-a-wastewater-recharge-site-contaminants-fate-and-transport-model
#17
Michael Rona, Ovadia Lev, Haim Gvirtzman
A 3-dimensional hydrologic groundwater flow and contaminant transport model was developed to address the feasibility and relevant time-scales for remediation of a large soil aquifer treatment (SAT) site for domestic wastewater. The model accounted for a range of organic pollutant retardation factors and biodegradation kinetics. In order to detect the effect of the most retained and the most refracted/recalcitrant pollutants, it was crucial to model fractions of different properties rather than with average set properties...
December 29, 2017: Ground Water
https://www.readbyqxmd.com/read/29280944/ngs-reveals-molecular-pathways-affected-by-obesity-and-weight-loss-related-changes-in-mirna-levels-in-adipose-tissue
#18
Alina Kuryłowicz, Zofia Wicik, Magdalena Owczarz, Marta Izabela Jonas, Marta Kotlarek, Michał Świerniak, Wojciech Lisik, Maurycy Jonas, Bartłomiej Noszczyk, Monika Puzianowska-Kuźnicka
Both obesity and weight loss may cause molecular changes in adipose tissue. This study aimed to characterize changes in adipose tissue miRNome in order to identify molecular pathways affected by obesity and weight changes. Next generation sequencing (NGS) was applied to identify microRNAs (miRNAs) differentially expressed in 47 samples of visceral (VAT) and subcutaneous (SAT) adipose tissues from normal-weight (N), obese (O) and obese after surgery-induced weight loss (PO) individuals. Subsequently miRNA expression was validated by real-time PCR in 197 adipose tissues and bioinformatics analysis performed to identify molecular pathways affected by obesity-related changes in miRNA expression...
December 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29280322/tissue-sodium-content-is-elevated-in-the-skin-and-subcutaneous-adipose-tissue-in-women-with-lipedema
#19
Rachelle Crescenzi, Adriana Marton, Paula M C Donahue, Helen B Mahany, Sarah K Lants, Ping Wang, Joshua A Beckman, Manus J Donahue, Jens Titze
OBJECTIVE: To test the hypothesis that tissue sodium and adipose content are elevated in patients with lipedema; if confirmed, this could establish precedence for tissue sodium and adipose content representing a discriminatory biomarker for lipedema. METHODS: Participants with lipedema (n = 10) and control (n = 11) volunteers matched for biological sex, age, BMI, and calf circumference were scanned with 3.0-T sodium and conventional proton magnetic resonance imaging (MRI)...
December 27, 2017: Obesity
https://www.readbyqxmd.com/read/29275995/effect-of-parental-history-of-diabetes-on-markers-of-inflammation-insulin-resistance-and-atherosclerosis-in-first-degree-relatives-of-patients-with-type-2-diabetes-mellitus
#20
Deepak Kumar Dash, Arun Kumar Choudhury, Mamta Singh, Swayamsidha Mangaraj, Binoy Kumar Mohanty, Anoj Kumar Baliarsinha
AIM AND OBJECTIVE: To study the effect of parental history of diabetes on markers of inflammation, insulin resistance, adiposity indices and carotid intima media thickness (cIMT) in first degree relatives of patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: Normal glucose tolerant (NGT) first degree relatives of T2DM patients of age group 20-40 years designated as FHpositive were enrolled in the cross sectional study. Depending on the parental history of diabetes they were divided into three groups: family history positive in father (FHfather), family history positive in mother (FHmother) and family history positive in both (FHboth)...
December 15, 2017: Diabetes & Metabolic Syndrome
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