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https://www.readbyqxmd.com/read/28548051/xenon-gas-field-ion-source-from-a-single-atom-tip
#1
Wei-Chiao Lai, Chun-Yueh Lin, Wei-Tse Chang, Po-Chang Li, Tsu-Yi Fu, Chia-Seng Chang, T T Tsong, Ing-Shouh Hwang
Focused ion beam (FIB) systems have become powerful diagnostic and modification tools for nanoscience and nanotechnology. Gas field ion sources (GFISs) built from atomic-size emitters offer the highest brightness among all ion sources and thus can improve the spatial resolution of FIB systems. Here we show that the Ir/W(111) single-atom tip (SAT) can emit high-brightness Xe(+) ion beams with a high current stability. The ion emission current versus extraction voltage was analyzed from 150 K up to 309 K. The optimal emitter temperature for maximum Xe(+) ion emission was ∼150 K and the reduced brightness at the Xe gas pressure of 1 × 10(-4) torr is two to three orders of magnitude higher than that of a Ga liquid metal ion source, and four to five orders of magnitude higher than that of a Xe inductively coupled plasma ion source...
May 26, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28545710/evaluation-of-hyperspectral-imaging-technology-in-patients-with-peripheral-vascular-disease
#2
Nathaniel Chiang, Jitendra K Jain, Jamie Sleigh, Thodur Vasudevan
BACKGROUND: Hyperspectral imaging technology is a novel method of using transcutaneous measurement of oxyhemoglobin (HT-Oxy) and deoxyhemoglobin (HT-Deoxy) concentrations to create a two-dimensional, color-coded "oxygen map." The aims of this study were to compare the use of a hyperspectral imaging device with the transcutaneous oxygen measurement (TCOM), ankle-brachial index (ABI), and severity of peripheral vascular disease (PVD) and to assess their correlations. METHODS: This prospective study recruited 294 participants divided into three distinct groups composed of healthy volunteers and patients with PVD...
May 22, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28545230/nanog-plays-a-hierarchical-role-in-the-transcription-network-regulating-the-pluripotency-and-plasticity-of-adipose-tissue-derived-stem-cells
#3
Maria Pitrone, Giuseppe Pizzolanti, Laura Tomasello, Antonina Coppola, Lorenzo Morini, Gianni Pantuso, Romina Ficarella, Valentina Guarnotta, Sebastio Perrini, Francesco Giorgino, Carla Giordano
The stromal vascular cell fraction (SVF) of visceral and subcutaneous adipose tissue (VAT and SAT) has increasingly come into focus in stem cell research, since these compartments represent a rich source of multipotent adipose-derived stem cells (ASCs). ASCs exhibit a self-renewal potential and differentiation capacity. Our aim was to study the different expression of the embryonic stem cell markers NANOG (homeobox protein NANOG), SOX2 (SRY (sex determining region Y)-box 2) and OCT4 (octamer-binding transcription factor 4) and to evaluate if there exists a hierarchal role in this network in ASCs derived from both SAT and VAT...
May 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28542807/genetic-diversity-virulotyping-and-antimicrobial-resistance-susceptibility-of-yersinia-enterocolitica-isolated-from-pigs-and-porcine-products-in-malaysia
#4
Kwai Lin Thong, Lai Kuan Tan, Peck Toung Ooi
BACKGROUND: The objectives of this study were to determine the antimicrobial resistance, virulotypes and genetic diversity of Yersinia enterocolitica isolated from uncooked porcine food and live pigs in Malaysia. RESULTS: Thirty-two non-repeat Y. enterocolitica strains of three bioserotypes (3 variant/O:3, n=27; 1B/O:8, n=3; 1A/O:5, n=2) were analysed. About 90% of strains were multidrug-resistant with MAR index <0.2 and majority of the strains were resistant to nalidixic acid, clindamycin, ampicillin, ticarcillin, tetracycline and amoxicillin...
May 24, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28542441/dot-or-sat-for-rifampicin-resistant-tuberculosis-a-non-randomized-comparison-in-a-high-hiv-prevalence-setting
#5
Erika Mohr, Johnny Daniels, Busisiwe Beko, Petros Isaakidis, Vivian Cox, Sarah Jane Steele, Odelia Muller, Leigh Snyman, Virginia De Azevedo, Amir Shroufi, Laura Trivino Duran, Jennifer Hughes
BACKGROUND: Daily directly-observed therapy (DOT) is recommended for rifampicin-resistant tuberculosis (RR-TB) patients throughout treatment. We assessed the impact of self-administered treatment (SAT) in a South African township with high rates of RR-TB and HIV. METHODS: Community-supported SAT for patients who completed the intensive phase was piloted in five primary care clinics in Khayelitsha. We compared final treatment outcomes among RR-TB patients initiating treatment before (standard-of-care (SOC)-cohort, January 2010-July 2013) and after the implementation of the pilot (SAT-cohort, January 2012-December 2014)...
2017: PloS One
https://www.readbyqxmd.com/read/28535911/validation-of-a-free-software-for-unsupervised-assessment-of-abdominal-fat-in-mri
#6
Michele Maddalo, Ivan Zorza, Stefano Zubani, Giorgio Nocivelli, Giulio Calandra, Pierantonio Soldini, Lorella Mascaro, Roberto Maroldi
PURPOSE: To demonstrate the accuracy of an unsupervised (fully automated) software for fat segmentation in magnetic resonance imaging. The proposed software is a freeware solution developed in ImageJ that enables the quantification of metabolically different adipose tissues in large cohort studies. METHODS: The lumbar part of the abdomen (19cm in craniocaudal direction, centered in L3) of eleven healthy volunteers (age range: 21-46years, BMI range: 21.7-31.6kg/m(2)) was examined in a breath hold on expiration with a GE T1 Dixon sequence...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28535854/influenza-a-world-of-discoveries-outbreaks-and-controversy
#7
Wendy S Barclay
Working in an area such as influenza is a free ticket into science communication, a pathway aided amply by the amazing evolutionary powers of the virus; regular outbreaks keep the media engaged and the audience keen. Everyone has heard of flu, and they probably already have an opinion: 'I don't take the vaccine, it gives me the flu anyway.' 'Didn't the government waste loads of money on that Tamiflu drug that doesn't work?' 'I've never had flu because I eat a banana every day and sleep with a boiled onion when I've sat next to someone on the train who was coughing...
May 23, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28534418/quantification-of-visceral-adipose-tissue-in-polycystic-ovary-syndrome-dual-energy-x-ray-absorptiometry-versus-magnetic-resonance-imaging
#8
Signe Frøssing, Malin Chatarina Nylander, Elizaveta Chabanova, Caroline Kistorp, Sven O Skouby, Jens Faber
Background Polycystic ovary syndrome (PCOS) is associated with frequent overweight and abdominal obesity. Quantifying visceral adipose tissue (VAT) in PCOS patients can be a tool to assess metabolic risk and monitor effects of treatment. The latest dual-energy X-ray absorptiometry (DXA) technology can measure VAT and subcutaneous adipose tissue (SAT) in a clinical setting. Purpose To compare DXA-measurements of VAT and SAT with the gold standard MRI in women with PCOS. Material and Methods A cross-sectional study of 67 overweight women with PCOS was performed...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28533768/novel-large-sulfur-bacteria-in-the-metagenomes-of-groundwater-fed-chemosynthetic-microbial-mats-in-the-lake-huron-basin
#9
Allison M Sharrar, Beverly E Flood, Jake V Bailey, Daniel S Jones, Bopaiah A Biddanda, Steven A Ruberg, Daniel N Marcus, Gregory J Dick
Little is known about large sulfur bacteria (LSB) that inhabit sulfidic groundwater seeps in large lakes. To examine how geochemically relevant microbial metabolisms are partitioned among community members, we conducted metagenomic analysis of a chemosynthetic microbial mat in the Isolated Sinkhole, which is in a deep, aphotic environment of Lake Huron. For comparison, we also analyzed a white mat in an artesian fountain that is fed by groundwater similar to Isolated Sinkhole, but that sits in shallow water and is exposed to sunlight...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28532512/inter-rater-reliability-of-kinesthetic-measurements-with-the-kinarm-robotic-exoskeleton
#10
Jennifer A Semrau, Troy M Herter, Stephen H Scott, Sean P Dukelow
BACKGROUND: Kinesthesia (sense of limb movement) has been extremely difficult to measure objectively, especially in individuals who have survived a stroke. The development of valid and reliable measurements for proprioception is important to developing a better understanding of proprioceptive impairments after stroke and their impact on the ability to perform daily activities. We recently developed a robotic task to evaluate kinesthetic deficits after stroke and found that the majority (~60%) of stroke survivors exhibit significant deficits in kinesthesia within the first 10 days post-stroke...
May 22, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28529148/postural-preference-and-musculoskeletal-complaints-in-oral-and-maxillofacial-surgeons
#11
Corey A Taylor, Robert A Strauss, Alvin M Best
PURPOSE: Oral and maxillofacial surgeons traditionally have musculoskeletal pain. The aim of this study was to determine the postural preferences of oral and maxillofacial surgeons and their effect on musculoskeletal pain. MATERIALS AND METHODS: The authors designed and implemented a cross-sectional study. The association of demographic characteristics with postural preferences and use of loupes was explored. Then, the relation of demographic characteristics, postural preferences, and use of loupes to painful musculoskeletal complaints was analyzed...
April 26, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28527771/aspirin-versus-aspirin-plus-clopidogrel-as-antithrombotic-treatment-following-transcatheter-aortic-valve-replacement-with-a-balloon-expandable-valve-the-arte-aspirin-versus-aspirin%C3%A2-clopidogrel-following%C3%A2-transcatheter-aortic-valve-implantation-randomized%C3%A2
#12
Josep Rodés-Cabau, Jean-Bernard Masson, Robert C Welsh, Bruno Garcia Del Blanco, Marc Pelletier, John G Webb, Faisal Al-Qoofi, Philippe Généreux, Gabriel Maluenda, Martin Thoenes, Jean-Michel Paradis, Chekrallah Chamandi, Vicenç Serra, Eric Dumont, Mélanie Côté
OBJECTIVE: The aim of this study was to compare aspirin plus clopidogrel with aspirin alone as antithrombotic treatment following transcatheter aortic valve replacement (TAVR) for the prevention of ischemic events, bleeding events, and death. BACKGROUND: Few data exist on the optimal antithrombotic therapy following TAVR. METHODS: This was a randomized controlled trial comparing aspirin (80 to 100 mg/day) plus clopidogrel (75 mg/day) (dual-antiplatelet therapy [DAPT]) versus aspirin alone (single-antiplatelet therapy [SAPT]) in patients undergoing TAVR with a balloon-expandable valve...
May 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28525636/movement-does-not-promote-recovery-of-motor-output-following-acute-experimental-muscle-pain
#13
Siobhan M Schabrun, Thorvaldur S Palsson, Tribikram Thapa, Thomas Graven-Nielsen
Objective.:  To examine the effect of motor activity on the magnitude and duration of altered corticomotor output following experimental muscle pain. Design. : Experimental, pre-post test. Setting. : University laboratory. Subjects. : Twenty healthy individuals. Methods.:  Participants were randomly allocated to a Rest or Movement group. The Rest group sat quietly without moving for the duration of the experiment...
May 19, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28524358/kripalu-yoga-for-military-veterans-with-ptsd-a-randomized-trial
#14
Kristen M Reinhardt, Jessica J Noggle Taylor, Jennifer Johnston, Abida Zameer, Seetal Cheema, Sat Bir S Khalsa
OBJECTIVES: This randomized controlled trial of yoga for military veterans and active duty personnel with posttraumatic stress disorder (PTSD) evaluated the efficacy of a 10-week yoga intervention on PTSD. METHOD: Fifty-one participants were randomized into yoga or no-treatment assessment-only control groups. Primary outcome measures included questionnaires and the Clinician Administered PTSD Scale. RESULTS: Both yoga (n = 9) and control (n = 6) participants showed significant decreases in reexperiencing symptoms, with no significant between-group differences...
May 19, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28523623/microbial-population-shift-caused-by-sulfamethoxazole-in-engineered-soil-aquifer-treatment-e-sat-system
#15
Ashwinkumar P Rudrashetti, Niti B Jadeja, Deepa Gandhi, Asha A Juwarkar, Abhinav Sharma, Atya Kapley, R A Pandey
The engineered-Soil Aquifer Treatment (e-SAT) system was exploited for the biological degradation of Sulfamethoxazole (SMX) which is known to bio-accumulate in the environment. The fate of SMX in soil column was studied through laboratory simulation for a period of 90 days. About 20 ppm SMX concentration could be removed in four consecutive cycles in e-SAT. To understand the microbial community change and biological degradation of SMX in e-SAT system, metagenomic analysis was performed for the soil samples before (A-EBD) and after SMX exposure (B-EBD) in the e-SAT...
June 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28523479/fatty-acids-have-different-adipogenic-differentiation-potentials-in-stromal-vascular-cells-isolated-from-abdominal-fat-in-laying-hens
#16
Alemu Regassa, Miyoung Suh, Jutika Datar, Chongxiao Chen, Woo Kyun Kim
This study was conducted to examine the effects of fatty acids (FA) with/without chicken serum (CS) on the expression of adipogenic transcripts and adipogenesis in chicken stromal vascular cells (SVC). In experiment 1, SVC were grown in DMEM containing 10% FBS (Control) and treated with 300 µM oleic acid (OLA) + FBS, linoleic acid (LNA) + FBS, palmitic acid (PAM) + FBS, or stearic acid (STA) + FBS for 48 h. In experiment 2, cells were grown in DMEM containing 5% CS and treated with 300 µM OLA (CS + OLA), PAM (CS + PAM), STA (CS + STA) or 200 µM LNA (CS + LNA) for 48 h...
May 18, 2017: Lipids
https://www.readbyqxmd.com/read/28523085/free-bone-grafts-for-mandibular-reconstruction-in-patients-who-have-not-received-radiotherapy-the-6-cm-rule-myth-or-reality
#17
Baljeet Nandra, Tirbod Fattahi, Tim Martin, Prav Praveen, Rui Fernandes, Sat Parmar
Bony reconstruction of the mandible after surgical resection results in improved rehabilitation and aesthetics. Composite tissue transfer has transformed reconstruction, particularly in patients who have received radiotherapy. However, there is morbidity related to free tissue transfer. Free nonvascularized bone grafts have much lower morbidity. Surgeons believe that free bone grafts greater than 6.0 cm are prone to failure. The aims of this study was to assess whether bone grafts greater than 6.0 cm in length have a high risk of failure...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28522656/comparison-between-different-measures-of-body-fat-with-kidney-function-decline-and-incident-ckd
#18
Magdalena Madero, Ronit Katz, Rachel Murphy, Anne Newman, Kushang Patel, Joachim Ix, Carmen Peralta, Suzanne Satterfield, Linda Fried, Michael Shlipak, Mark Sarnak
BACKGROUND AND OBJECTIVES: Although anthropometric measures of body fat are associated with development of CKD, they may not be able to distinguish between various forms of fat and therefore may be less accurate than computed tomography (CT) measures. We compared the association of CT and anthropometric measures of obesity with kidney outcomes in the Health Aging and Body Composition Study. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Participants were recruited from March of 1997 through July of 1998...
May 18, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28522646/mr-spectroscopy-of-hepatic-fat-and-adiponectin-and-leptin-levels-during-testosterone-therapy-in-type-2-diabetes-a-randomized-double-blinded-placebo-controlled-trial
#19
Line Velling Magnussen, Poul Erik Andersen, Anabel Diaz, Jelena Markovic Ostojic, Kurt Højlund, David M Hougaard, Anders Nymark Christensen, Torben Leo Nielsen, Marianne Skovsager Andersen
BACKGROUND: Men with type 2 diabetes mellitus (T2D) often have lowered testosterone levels and an increased risk of cardiovascular disease (CVD). Ectopic fat increases the risk of CVD, whereas subcutaneous gluteofemoral fat protects against CVD and has a beneficial adipokine secreting profile. HYPOTHESIS: Testosterone replacement therapy (TRT) may reduce the content of ectopic fat and improve the adipokine profile in men with T2D. DESIGN AND METHODS: A randomized, double-blinded, placebo-controlled study in 39 men aged 50-70 years with T2D and bioavailable testosterone levels <7...
May 18, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28520818/evaluation-of-a-real-time-method-of-simultaneous-amplification-and-testing-in-diagnosis-of-mycoplasma-pneumoniae-infection-in-children-with-pneumonia
#20
Wei Li, You-Hong Fang, Hong-Qiang Shen, De-Hua Yang, Qiang Shu, Shi-Qiang Shang
Mycoplasma pneumoniae (M. pneumoniae) infection can cause community acquired pneumonia in children. A real-time method of simultaneous amplification and testing of M. pneumoniae (SAT-MP) was developed to diagnose M. pneumoniae targeting a region of the ribosomal RNA. The SAT-MP assay can accurately identify M. pneumoniae with a detection range from 101 to 107 CFU/ml. In this study, the specimens from 315 children with pneumonia were collected and analyzed by SAT-MP in parallel with real-time PCR method and IgM ELISA assay...
2017: PloS One
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