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https://www.readbyqxmd.com/read/28434583/a-proposal-for-new-neurorehabilitative-intervention-on-moebius-syndrome-patients-after-smile-surgery-proof-of-concept-based-on-mirror-neuron-system-properties-and-hand-mouth-synergistic-activity
#1
REVIEW
Pier Francesco Ferrari, Anna Barbot, Bernardo Bianchi, Andrea Ferri, Gioacchino Garofalo, Nicola Bruno, Gino Coudé, Chiara Bertolini, Martina Ardizzi, Ylenia Nicolini, Mauro Belluardo, Elisa De Stefani
Studies of the last twenty years on the motor and premotor cortices of primates demonstrated that the motor system is involved in the control and initiation of movements, and in higher cognitive processes, such as action understanding, imitation, and empathy. Mirror neurons are only one example of such theoretical shift. Their properties demonstrate that motor and sensory processing are coupled in the brain. Such knowledge has been also central for designing new neurorehabilitative therapies for patients suffering from brain injuries and consequent motor deficits...
May 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28432328/tactile-flow-overides-other-cues-to-self-motion
#2
Laurence R Harris, Kenzo Sakurai, William H A Beaudot
Vestibular-somatosensory interactions are pervasive in the brain but it remains unclear why. Here we explore the contribution of tactile flow to processing self-motion. We assessed two aspects of self-motion: timing and speed. Participants sat on an oscillating swing and either kept their hands on their laps or rested them lightly on an earth-stationary surface. They viewed a grating oscillating at the same frequency as their motion and judged its phase or, in a separate experiment, its speed relative to their perceived motion...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28429889/omentin-treatment-of-epicardial-fat-improves-its-anti-inflammatory-activity-and-paracrine-benefit-on-smooth-muscle-cells
#3
Ángel Fernández-Trasancos, Rosa María Agra, Jose María García-Acuña, Ángel Luis Fernández, José Ramón González-Juanatey, Sonia Eiras
OBJECTIVE: Epicardial adipose tissue (EAT) in coronary artery disease is insulin resistant and has a proinflammatory profile. This study examined the regulation of EAT by exogenous omentin and its consequence on vascular cells. METHODS: Stromal vascular cells (SC) of EAT and subcutaneous adipose tissue (SAT) from patients who underwent heart surgery were cultured and exposed to adipogenic factors with or without omentin. Proinflammatory cytokine regulation by omentin was analyzed in SC and mature adipocytes...
April 21, 2017: Obesity
https://www.readbyqxmd.com/read/28428714/predictors-for-difficult-cecal-insertion-in-colonoscopy-the-impact-of-obesity-indices
#4
Soo Yun Moon, Byung Chang Kim, Dae Kyung Sohn, Kyung Su Han, Bun Kim, Chang Won Hong, Bum Joon Park, Kum Hei Ryu, Ji Hyung Nam
AIM: To identify the factors influencing cecal insertion time (CIT) and to evaluate the effect of obesity indices on CIT. METHODS: We retrospectively reviewed the data for participants who received both colonoscopy and abdominal computed tomography (CT) from February 2008 to May 2008 as part of a comprehensive health screening program. Age, gender, obesity indices [body mass index (BMI), waist-to-hip circumference ratio (WHR), waist circumference (WC), visceral adipose tissue (VAT) volume and subcutaneous adipose tissue (SAT) volume on abdominal CT], history of prior abdominal surgery, constipation, experience of the colonoscopist, quality of bowel preparation, diverticulosis and time required to reach the cecum were analyzed...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28428317/complete-nucleotide-sequence-of-an-isolate-of-grapevine-satellite-virus-and-evidence-for-the-presence-of-multimeric-forms-in-an-infected-grapevine
#5
T Candresse, A Marais, S Theil, C Faure, T Lacombe, J M Boursiquot
The complete nucleotide sequence of an isolate of grapevine satellite virus (GV-Sat) was determined by next-generation sequencing (NGS) and compared with the single available complete sequence. The NGS data unexpectedly provided evidence for the existence of multimeric forms of GV-Sat, which were experimentally confirmed, allowing the redefinition of GV-Sat genomic ends.
April 20, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28425571/clinical-factors-affecting-costs-in-patients-receiving-systemic-antifungal-therapy-in-intensive-care-units-in-greece-results-from-the-estimator-study
#6
A Armaganidis, S Nanas, E Antoniadou, K Mandragos, K Liakou, A Koutsoukou, G Baltopoulos, G Nakos, A Kounougeri, K Ganas, A Prekates, M Kompoti, D Georgopoulos, I Pneumatikos, E Zakynthinos
Invasive fungal infections are common in intensive care units (ICUs) but there is a great variability in factors affecting costs of different antifungal treatment strategies in clinical practice. To determine factors affecting treatment cost in adult ICU patients with or without documented invasive fungal infection receiving systemic antifungal therapy (SAT) we have performed a prospective, multicentre, observational study enrolling patients receiving SAT in participating ICUs in Greece. During the study period, 155 patients received SAT at 14 participating ICUs: 37 (23...
April 20, 2017: Mycoses
https://www.readbyqxmd.com/read/28420971/dynamic-increase-in-corticomuscular-coherence-during-bilateral-cyclical-ankle-movements
#7
Takashi Yoshida, Kei Masani, Karl Zabjek, Robert Chen, Milos R Popovic
In humans, the midline primary motor cortex is active during walking. However, the exact role of such cortical participation is unknown. To delineate the role of the primary motor cortex in walking, we examined whether the primary motor cortex would activate leg muscles during movements that retained specific requirements of walking (i.e., locomotive actions). We recorded electroencephalographic and electromyographic signals from 15 healthy, young men while they sat and performed bilateral, cyclical ankle movements...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28416251/initial-asthma-severity-assessment-tools-as-predictors-of-hospitalization
#8
Natalia Paniagua, Amaia Elosegi, Isabel Duo, Ana Fernandez, Elisa Mojica, Lorea Martinez-Indart, Santiago Mintegi, Javier Benito
BACKGROUND: Assessment tools to classify and prioritize patients, such as systems of triage, and indicators of severity, such as clinical respiratory scores, are helpful in guiding the flow of asthmatic patients in the emergency department. OBJECTIVE: Our aim was to assess the performance of the Pediatric Assessment Triangle (PAT), triage level (TL), Pulmonary Score (PS), and initial O2 saturation (O2 sat), in predicting hospitalization in pediatric acute asthma exacerbations...
April 14, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28414467/variation-of-bacterial-communities-with-water-quality-in-an-urban-tropical-catchment
#9
Jean Pierre Nshimyimana, Adam Joshua Ehrich Freedman, Peter Shanahan, Lloyd C H Chua, Janelle Renee Thompson
A major challenge for assessment of water quality in tropical environments is the natural occurrence and potential growth of Fecal Indicator Bacteria (FIB). To gain a better understanding of the relationship between measured levels of FIB and the distribution of sewage-associated bacteria including potential pathogens in the tropics this study compared the abundance of FIB (Total coliforms and E. coli) and the Bacteroidales (HF183 marker) with bacterial community structure determined by next-generation amplicon sequencing...
April 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28414426/two-distinct-assembly-states-of-cysteine-regulatory-complex-of-salmonella-typhimurium-are-regulated-by-enzyme-substrate-cognate-pairs
#10
Abhishek Kaushik, Mary Krishna Ekka, Sangaralingam Kumaran
Serine acetyltransferase (SAT) and O-acetylserine sulfhydrylase (OASS), which catalyze last two steps of cysteine biosynthesis, interact and form Cysteine Regulatory Complex (CRC). The current model of Salmonella typhimurium predicts that CRC is composed of one [SAT]hexmer unit and two molecules of [OASS]dimer. However, it is not clear why [SAT]hexamer can not engage all of its six high-affinity binding sites. We examined the assembly state(s) of CRC by size exclusion chromatography (SEC), analytical ultracentrifugation (AUC), isothermal titration calorimetry (ITC), and surface plasmon resonance (SPR) approaches...
April 17, 2017: Biochemistry
https://www.readbyqxmd.com/read/28413567/differential-adipokine-dna-methylation-and-gene-expression-in-subcutaneous-adipose-tissue-from-adult-offspring-of-women-with-diabetes-in-pregnancy
#11
Azadeh Houshmand-Oeregaard, Ninna S Hansen, Line Hjort, Louise Kelstrup, Christa Broholm, Elisabeth R Mathiesen, Tine D Clausen, Peter Damm, Allan Vaag
BACKGROUND: Offspring of women with diabetes in pregnancy are at increased risk of type 2 diabetes mellitus (T2DM), potentially mediated by epigenetic mechanisms. The adipokines leptin, adiponectin, and resistin (genes: LEP, ADIPOQ, RETN) play key roles in the pathophysiology of T2DM. We hypothesized that offspring exposed to maternal diabetes exhibit alterations in epigenetic regulation of subcutaneous adipose tissue (SAT) adipokine transcription. We studied adipokine plasma levels, SAT gene expression, and DNA methylation of LEP, ADIPOQ, and RETN in adult offspring of women with gestational diabetes (O-GDM, N = 82) or type 1 diabetes (O-T1DM, N = 67) in pregnancy, compared to offspring of women from the background population (O-BP, N = 57)...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28411199/impact-of-fabp1-scp-2-scp-x-gene-ablation-tko-on-hepatic-phytol-metabolism-in-mice
#12
Stephen M Storey, Huan Huang, Avery L McIntosh, Gregory G Martin, Ann B Kier, Friedhelm Schroeder
Studies in vitro have suggested that both sterol carrier protein-2/sterol carrier protein-x (Scp-2/Scp-x) and liver fatty acid binding protein (Fabp1) gene products facilitate hepatic uptake and metabolism of lipotoxic dietary phytol. However, interpretation of physiological function in mice singly gene ablated in the Scp-2/Scp-x has been complicated by concomitant upregulation of FABP1. The work presented herein provides several novel insights: i) An ANS displacement assay showed that neither SCP-2 nor L-FABP bound phytol, but both had high affinity for its metabolite, phytanic acid; ii) GC/MS studies with phytol-fed wild-type (WT) and Fabp1/Scp-2/SCP-x gene ablated (TKO) mice showed that TKO exacerbated hepatic accumulation of phytol metabolites in vivo in females and less so in males...
April 14, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28409515/effects-of-stretching-and-fatigue-on-peak-torque-muscle-imbalance-and-stability
#13
Pablo B Costa, Cassio V Ruas, Cory M Smith
BACKGROUND: The present study examined the acute effects of hamstrings stretching and fatigue on knee extension and flexion peak torque (PT), hamstrings to quadriceps (H:Q) ratio, and postural stability. METHODS: Seventeen women (mean ± SD age = 21.8 ± 2.1 yrs; body mass = 63.0 ± 10.5 kg; height = 164.7 ± 6.2 cm) and eighteen men (25.8 ± 4.6 yrs; 83.6 ± 13.2 kg; 175.3 ± 6.0 cm) took part in three laboratory visits. The first visit was a familiarization session, and the subsequent two visits were randomly assigned as a control or stretching condition...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28406704/pro-inflammatory-gene-expression-in-adipose-tissue-of-patients-with-atherosclerosis
#14
S Čejková, I Králová Lesná, J Froněk, L Janoušek, A Králová, J Ždychová, R Poledne
Inflammatory changes, both in the arterial wall and adipose tissue, play a crucial role in the development of atherosclerosis. We measured the gene expression of tumor necrosis factor-alpha (TNFalpha), monocyte chemoattractant protein-1 (MCP-1), and interleukin 6 (IL-6) in adipose tissue (AT) of living kidney donors (LKD) and patients with peripheral arterial disease (PAD). Quantitative polymerase chain reaction (qPCR) and flow cytometry analyses were performed in subcutaneous (SAT), visceral (VAT), and perivascular adipose tissue (PVAT)...
April 12, 2017: Physiological Research
https://www.readbyqxmd.com/read/28406702/an-alternatively-activated-macrophage-marker-cd163-in-severely-obese-patients-the-influence-of-very-low-calorie-diet-and-bariatric-surgery
#15
A Cinkajzlová, Z Lacinová, J Kloučková, P Kaválková, P Trachta, M Kosák, J Krátký, M Kasalický, K DoleŽalová, M Mráz, M Haluzík
CD163 is a marker of macrophages with anti-inflammatory properties and its soluble form (sCD163) is considered a prognostic predictor of several diseases including type 2 diabetes mellitus (T2DM). We explored sCD163 levels at baseline and after very low-calorie diet (VLCD) or bariatric surgery in 32 patients with obesity (20 undergoing VLCD and 12 bariatric surgery), 32 obese patients with T2DM (22 undergoing VLCD and 10 bariatric surgery), and 19 control subjects. We also assessed the changes of CD163 positive cells of monocyte-macrophage lineage in peripheral blood and subcutaneous adipose tissue (SAT) in subset of patients...
April 12, 2017: Physiological Research
https://www.readbyqxmd.com/read/28403191/visceral-adipose-tissue-but-not-subcutaneous-adipose-tissue-is-associated-with-urine-and-serum-metabolites
#16
Inga Schlecht, Wolfram Gronwald, Gundula Behrens, Sebastian E Baumeister, Johannes Hertel, Jochen Hochrein, Helena U Zacharias, Beate Fischer, Peter J Oefner, Michael F Leitzmann
Obesity is a complex multifactorial phenotype that influences several metabolic pathways. Yet, few studies have examined the relations of different body fat compartments to urinary and serum metabolites. Anthropometric phenotypes (visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), the ratio between VAT and SAT (VSR), body mass index (BMI), waist circumference (WC)) and urinary and serum metabolite concentrations measured by nuclear magnetic resonance spectroscopy were measured in a population-based sample of 228 healthy adults...
2017: PloS One
https://www.readbyqxmd.com/read/28402897/green-synthesis-of-a-magnetic-hybrid-adsorbent-cofe2o4-nom-removal-of-chromium-from-industrial-effluent-and-evaluation-of-the-catalytic-potential-of-recovered-chromium-ions
#17
Daiane R S Cruz, Bruna T J Santos, Graziele C Cunha, Luciane P C Romão
This work describes the removal of chromium ions from industrial effluent using a hybrid magnetic adsorbent, CoFe2O4/NOM, synthesized using water rich in natural organic matter. The hybrid obtained at ambient temperature (HbAmb) was calcined at 200, 400, and 800°C for 2h, and formation of the cobalt ferrite phase was confirmed by XRD, which indicated the presence of NOM in the structure of the material. Removal tests showed that HbAmb provided efficient removal of chromium at the natural pH of the effluent, while the other materials were effective at pH 6...
March 31, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28400716/evaluation-of-the-display-of-cognitive-state-feedback-to-drive-adaptive-task-sharing
#18
Michael C Dorneich, Břetislav Passinger, Christopher Hamblin, Claudia Keinrath, Jiři Vašek, Stephen D Whitlow, Martijn Beekhuyzen
This paper presents an adaptive system intended to address workload imbalances between pilots in future flight decks. Team performance can be maximized when task demands are balanced within crew capabilities and resources. Good communication skills enable teams to adapt to changes in workload, and include the balancing of workload between team members This work addresses human factors priorities in the aviation domain with the goal to develop concepts that balance operator workload, support future operator roles and responsibilities, and support new task requirements, while allowing operators to focus on the most safety critical tasks...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28393064/exploring-systems-that-support-good-clinical-care-in-indigenous-primary-health-care-services-a-retrospective-analysis-of-longitudinal-systems-assessment-tool-data-from-high-improving-services
#19
Cindy Woods, Karen Carlisle, Sarah Larkins, Sandra Claire Thompson, Komla Tsey, Veronica Matthews, Ross Bailie
BACKGROUND: Continuous Quality Improvement is a process for raising the quality of primary health care (PHC) across Indigenous PHC services. In addition to clinical auditing using plan, do, study, and act cycles, engaging staff in a process of reflecting on systems to support quality care is vital. The One21seventy Systems Assessment Tool (SAT) supports staff to assess systems performance in terms of five key components. This study examines quantitative and qualitative SAT data from five high-improving Indigenous PHC services in northern Australia to understand the systems used to support quality care...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28392838/global-gene-expression-in-escherichia-coli-isolated-from-the-diseased-ocular-surface-of-the-human-eye-with-a-potential-to-form-biofilm
#20
Konduri Ranjith, Kotakonda Arunasri, Gundlapally Sathyanarayana Reddy, HariKrishna Adicherla, Savitri Sharma, Sisinthy Shivaji
BACKGROUND: Escherichia coli, the gastrointestinal commensal, is also known to cause ocular infections such as conjunctivitis, keratitis and endophthalmitis. These infections are normally resolved by topical application of an appropriate antibiotic. But, at times these E. coli are resistant to the antibiotic and this could be due to formation of a biofilm. In this study ocular E. coli from patients with conjunctivitis, keratitis or endophthalmitis were screened for their antibiotic susceptibility and biofilm formation potential...
2017: Gut Pathogens
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