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https://www.readbyqxmd.com/read/27908493/diagnostic-accuracy-of-the-kampala-trauma-score-using-estimated-abbreviated-injury-scale-scores-and-physician-opinion
#1
Andrew Gardner, Paa Kobina Forson, George Oduro, Barclay Stewart, Nkechi Dike, Paul Glover, Ronald F Maio
BACKGROUND: The Kampala Trauma Score (KTS) has been proposed as a triage tool for use in low- and middle-income countries (LMICs). This study aimed to examine the diagnostic accuracy of KTS in predicting emergency department outcomes using timely injury estimation with Abbreviated Injury Scale (AIS) score and physician opinion to calculate KTS scores. METHODS: This was a diagnostic accuracy study of KTS among injured patients presenting to Komfo Anokye Teaching Hospital A&E, Ghana...
November 21, 2016: Injury
https://www.readbyqxmd.com/read/27906308/linear-and-nonlinear-optical-characterization-of-self-assembled-large-area-gold-nanosphere-metasurfaces-with-sub-nanometer-gaps
#2
Jake Fontana, Melissa Maldonado, Nicholas Charipar, Scott A Trammell, Rafaela Nita, Jawad Naciri, Alberto Pique, Banahalli Ratna, Anderson S L Gomes
We created centimeter-scale area metasurfaces consisting of a quasi-hexagonally close packed monolayer of gold nanospheres capped with alkanethiol ligands on glass substrates using a directed self-assembly approach. We experimentally characterized the morphology and the linear and nonlinear optical properties of metasurfaces. We show these metasurfaces, with interparticle gaps of 0.6 nm, are modeled well using a classical (without charge transfer) description. We find a large dispersion of linear refractive index, ranging from values less than vacuum, 0...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27902586/neurological-psychological-and-cognitive-disorders-in-patients-with-chronic-kidney-disease-on-conservative-and-replacement-therapy
#3
Silvia Lai, Oriano Mecarelli, Patrizia Pulitano, Roberto Romanello, Leonardo Davi, Alessia Zarabla, Amalia Mariotti, Maria Carta, Giorgia Tasso, Luca Poli, Anna Paola Mitterhofer, Massimo Testorio, Nicla Frassetti, Paola Aceto, Alessandro Galani, Carlo Lai
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients. The aim of this study was to assess the neurological, psychological, and cognitive imbalance in patients with CKD on conservative and replacement therapy.Seventy-four clinically stable patients affected by CKD on conservative therapy, replacement therapy (hemodialysis (HD), peritoneal dialysis (PD)), or with kidney transplantation (KT) and 25 healthy controls (HC), matched for age and sex were enrolled...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27900559/upregulated-tnf-expression-1%C3%A2-year-after-bariatric-surgery-reflects-a-cachexia-like-state-in-subcutaneous-adipose-tissue
#4
Alexander Jürets, Bianca Karla Itariu, Magdalena Keindl, Gerhard Prager, Felix Langer, Viktor Grablowitz, Maximilian Zeyda, Thomas Michael Stulnig
BACKGROUND: Adipose tissue dysfunction contributes to obesity-associated chronic diseases. In the first year after bariatric surgery, obese patients significantly improve their metabolic status upon losing weight. We aimed to investigate whether changes in subcutaneous adipose tissue gene expression reflect a restoration of a healthy lean phenotype after bariatric surgery. METHODS: Thirty-one severely obese patients (BMI ≥ 40 kg/m(2)) were examined before and after surgery...
November 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27900194/chair-based-fidgeting-and-energy-expenditure
#5
Gabriel A Koepp, Graham K Moore, James A Levine
INTRODUCTION: Sedentariness is associated with chronic health conditions, impaired cognitive function and obesity. Work contributes significantly to sedentariness because many work tasks necessitate sitting. Few sustained solutions exist to reverse workplace sedentariness. Here, we evaluated a chair and an under-table device that were designed to promote fidgeting while seated. Our hypothesis was that an under-table leg-fidget bar and/or a fidget-promoting chair significantly increased energy expenditure...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899921/high-prevalence-of-%C3%AE-lactamase-and-plasmid-mediated-quinolone-resistance-genes-in-extended-spectrum-cephalosporin-resistant-escherichia-coli-from-dogs-in-shaanxi-china
#6
Xiaoqiang Liu, Haixia Liu, Yinqian Li, Caiju Hao
Objective: The aim of this study was to investigate the occurrence and molecular characterization of extended-spectrum β-lactamases (ESBL), plasmid-mediated AmpC β-lactamase (pAmpC) and carbapenemases as well as plasmid-mediated quinolone-resistant (PMQR) among extended-spectrum cephalosporin-resistant (ESC-R) Escherichia coli from dogs in Shaanxi province in China. Methods: A total of 40 ESC-R Escherichia coli selected from 165 Extraintestinal pathogenic E. coli (ExPEC) isolated from dogs were screened and characterized for the genes encoding for the ESBLs, pAmpC, carbapenemases and PMQR genes by PCR and sequencing...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27897414/a-comparative-study-of-software-programmes-for-cross-sectional-skeletal-muscle-and-adipose-tissue-measurements-on-abdominal-computed-tomography-scans-of-rectal-cancer-patients
#7
Jeroen L A van Vugt, Stef Levolger, Arvind Gharbharan, Marcel Koek, Wiro J Niessen, Jacobus W A Burger, Sten P Willemsen, Ron W F de Bruin, Jan N M IJzermans
BACKGROUND: The association between body composition (e.g. sarcopenia or visceral obesity) and treatment outcomes, such as survival, using single-slice computed tomography (CT)-based measurements has recently been studied in various patient groups. These studies have been conducted with different software programmes, each with their specific characteristics, of which the inter-observer, intra-observer, and inter-software correlation are unknown. Therefore, a comparative study was performed...
November 22, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27897412/systemic-inflammation-body-composition-and-physical-performance-in-old-community-dwellers
#8
Riccardo Calvani, Federico Marini, Matteo Cesari, Thomas W Buford, Todd M Manini, Marco Pahor, Christiaan Leeuwenburgh, Roberto Bernabei, Francesco Landi, Emanuele Marzetti
BACKGROUND: Chronic inflammation, changes in body composition, and declining physical function are hallmarks of the ageing process. The aim of the present study was to provide a preliminary characterisation of the relationship among these age-related phenomena via multivariate modelling. METHODS: Thirty-five old adults (OAs) and 17 young adults (YAs) were enrolled. The volume of skeletal muscle, subcutaneous adipose tissue (SAT), and intermuscular adipose tissue (IMAT) of the thigh was quantified by three-dimensional magnetic resonance imaging...
August 8, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27890441/the-ability-for-cocaine-and-cocaine-associated-cues-to-compete-for-attention
#9
Kyle K Pitchers, Taylor R Wood, Cari J Skrzynski, Terry E Robinson, Martin Sarter
In humans, reward cues, including drug cues in addicts, are especially effective in biasing attention towards them, so much so they can disrupt ongoing task performance. It is not known, however, whether this happens in rats. To address this question, we developed a behavioral paradigm to assess the capacity of an auditory drug (cocaine) cue to evoke cocaine-seeking behavior, thus distracting thirsty rats from performing a well-learned sustained attention task (SAT) to obtain a water reward. First, it was determined that an auditory cocaine cue (tone-CS) reinstated drug-seeking equally in sign-trackers (STs) and goal-trackers (GTs), which otherwise vary in the propensity to attribute incentive salience to a localizable drug cue...
November 24, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27875118/women-s-health-is-personal-more-technologies-by-and-for-women-are-moving-into-the-mainstream-thanks-in-part-to-personalized-medicine
#10
Jennifer Berglund
One fall day in Boston, Ridhi Tariyal sat on an examination table in her primary care doctor's office. Her doctor sat across from her, hurriedly transcribing notes as Tariyal responded to the doctor's questions. It was the end of Tariyal's physical, and the waiting room was full. "Do you have any questions?" the doctor asked, not turning away from the computer screen.
November 2016: IEEE Pulse
https://www.readbyqxmd.com/read/27872962/l-cysteine-metabolism-and-fermentation-in-microorganisms
#11
Hiroshi Takagi, Iwao Ohtsu
L-Cysteine is an important amino acid both biologically and commercially. Although most amino acids are industrially produced by microbial fermentation, L-cysteine has been mainly produced by protein hydrolysis. Due to environmental and safety problems, synthetic or biotechnological products have been preferred in the market. Here, we reviewed L-cysteine metabolism, including biosynthesis, degradation, and transport, and biotechnological production (including both enzymatic and fermentation processes) of L-cysteine...
November 22, 2016: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/27871812/effects-of-roux-en-y-gastric-bypass-and-sleeve-gastrectomy-on-bone-mineral-density-and-marrow-adipose-tissue
#12
Miriam A Bredella, Logan B Greenblatt, Alireza Eajazi, Martin Torriani, Elaine W Yu
Bariatric surgery is associated with bone loss but skeletal consequences may differ between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), the two most commonly performed bariatric procedures. Furthermore, severe weight loss is associated with high marrow adipose tissue (MAT); however, MAT is also increased in visceral adiposity. The purpose of our study was to determine the effects of RYGB and SG on BMD and MAT. We hypothesized that both bariatric procedures would lead to a decrease in BMD and MAT...
November 15, 2016: Bone
https://www.readbyqxmd.com/read/27870825/evaluation-of-pediatric-liver-transplantation-related-artery-complications-using-intra-operative-multi-parameter-ultrasonography
#13
Xiuyun Ren, Junhui Guan, Nong Gao, Hong Niu, Jie Tang
BACKGROUND This article discusses the value of using multi-parameter evaluation of intra-operative ultrasonography in evaluating pediatric liver transplantation-related arterial complications. MATERIAL AND METHODS Sixty-eight children receiving a liver transplant underwent intraoperative ultrasonography for monitoring of artery hemodynamics. The ultrasonic measurement parameters included the diameters of the hepatic artery (HA) of the donor and anastomotic stoma, peak systolic velocity (PSV), resistance index (RI), acceleration time (SAT), and blood flow volume...
November 21, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27867378/improved-pathogenicity-of-a-beet-black-scorch-virus-variant-by-low-temperature-and-co-infection-with-its-satellite-rna
#14
Jin Xu, Deshui Liu, Yongliang Zhang, Ying Wang, Chenggui Han, Dawei Li, Jia-Lin Yu, Xian-Bing Wang
Co-infection of none-coding satellite RNAs (sat-RNAs) usually inhibits replication and attenuates disease symptoms of helper viruses. However, we find that the sat-RNA of Beet black scorch virus (BBSV) and low temperature (18°C) additively enhance the systemic infection of BBSV in Nicotiana benthamiana. Northern blotting hybridization revealed a relatively reduced accumulation of BBSV-derived small interfering RNAs (siRNAs) in presence of sat-RNA as compared to that of BBSV alone. Cloning and sequencing of total small RNAs showed that more than 50% of the total small RNAs sequenced from BBSV-infected plants were BBSV-siRNAs, whereas the abundance of sat-siRNAs were higher than BBSV-siRNAs in the sat-RNA co-infected plants, indicating that the sat-RNA occupies most of the silencing components and possibly relieves the RNA silencing-mediated defense against BBSV...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27866704/standardized-ultrasound-measurement-of-subcutaneous-fat-patterning-high-reliability-and-accuracy-in-groups-ranging-from-lean-to-obese
#15
Paul Störchle, Wolfram Müller, Marietta Sengeis, Helmut Ahammer, Alfred Fürhapter-Rieger, Norbert Bachl, Sonja Lackner, Sabrina Mörkl, Sandra Holasek
A recently standardized ultrasound technique for measuring subcutaneous adipose tissue (SAT) was applied to normal-weight, overweight and obese persons. Eight measurement sites were used: upper abdomen, lower abdomen, erector spinae, distal triceps, brachioradialis, lateral thigh, front thigh and medial calf. Fat compression was avoided. Fat patterning in 38 participants (body mass index: 18.6-40.3 kgm(-2); SAT thickness sums from eight sites: 12-245 mm) was evaluated using a software specifically designed for semi-automatic multiple thickness measurements in SAT (sound speed: 1450 m/s) that also quantifies embedded fibrous structures...
November 17, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27866494/brucellosis-as-a-neglected-disease-in-a-neglected-population-a-seroepidemiological-study-of-migratory-nomads-in-the-fars-province-of-iran
#16
B Honarvar, M Moghadami, K B Lankarani, M A Davarpanah, M Ataolahi, A Farbod, E Eskandari, M Panahi, A Ghorbani, Z Zahiri, R Tabrizi, M Pourjafar, S M M Heidari
This study assessed the seroprevalence of brucellosis and its risk factors in migratory nomads in the Fars province of Iran. Active brucellosis was defined as the combination of clinical symptoms, including fever, chills, night sweats, headache, low back pain, arthralgia, or myalgia, and positive laboratory testing, including either a serum agglutination test (SAT) ⩾1:80 with a 2-mercaptoethanol (2-ME) test ⩾1:40, or a SAT <1:80 combined with a positive Coombs Wright test (CWT) at a titre of at least threefold higher than SAT titre results...
November 21, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27866033/bone-scintigraphy-for-the-diagnosis-of-the-responsible-level-of-osteoporotic-vertebral-compression-fractures-in-percutaneous-balloon-kyphoplasty
#17
Toshiyuki Okazaki, Hiroshi Nakagawa, Kenji Yagi, Hitoshi Hayase, Shinji Nagahiro, Koji Saito
OBJECTIVES: This study was to investigate the efficacy of bone scintigraphy in order to diagnose the correct level of vertebral compression fractures (VCF) for the severe back pain before balloon kyphoplasty (BKP) was performed. PATIENTS AND METHODS: A total of 30 consecutive patients were treated with BKP for 38 times since May 2012. Eleven patients had acute multi-level VCFs. Bone scintigraphy was performed preoperatively except for the first case and the case with a chronic course and the level responsible for the pain was defined with bone scintigraphy...
November 12, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27864746/revalidation-of-the-sat-chit-ananda-scale
#18
Kamlesh Singh, Pulkit Khanna, Meenakshi Khosla, Mounica Rapelly, Akarsh Soni
Sat-Chit-Ananda is an indigenous construct that refers to absolute bliss and consciousness. The present study aimed to strengthen the psychometric properties of the newly developed Sat-Chit-Ananda scale (Singh et al. in Int J Vedic Found Manag 1(2):54-74, 2014). A total of 398 students aged 17-36 years (mean age = 21.33 years, SD = 2.2, 70% males) participated in this study. An exploratory as well as confirmatory factor analysis was computed for the 17-item scale. Its' concurrent validity was established by assessing its correlation with other well-being measures, namely Flourishing (Diener et al...
November 18, 2016: Journal of Religion and Health
https://www.readbyqxmd.com/read/27864166/perivascular-adipose-tissue-inflammation-and-coronary-artery-disease-an-autopsy-study-protocol
#19
Daniela Souza Farias-Itao, Carlos Augusto Pasqualucci, Aline Nishizawa, Luiz Fernando Ferraz Silva, Fernanda Marinho Campos, Karen Cristina Souza da Silva, Renata Elaine Paraizo Leite, Lea Tenenholz Grinberg, Renata Eloah Lucena Ferretti-Rebustini, Wilson Jacob Filho, Claudia Kimie Suemoto
BACKGROUND: Perivascular adipose tissue (PAT) inflammation may have a role in coronary artery disease (CAD) pathophysiology. However, most evidence has come from samples obtained during surgical procedures that may imply in some limitations. Moreover, the role of B lymphocytes and inflammation in PAT that is adjacent to unstable atheroma plaques has not been investigated in humans using morphometric measurements. OBJECTIVE: The objective of this study is to investigate the inflammation in PAT, subcutaneous, and perirenal adipose tissues (SAT and PrAT) among chronic CAD, acute CAD, and control groups in an autopsy study...
November 18, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27862950/region-specific-effects-of-oestradiol-on-adipose-derived-stem-cell-differentiation-in-post-menopausal-women
#20
Kimberly A Cox-York, Christopher B Erickson, Rocio I Pereira, Daniel H Bessesen, Rachael E Van Pelt
The goal of this study was to determine the effect of acute transdermal 17β-oestradiol (E2 ) on the adipogenic potential of subcutaneous adipose-derived stem cells (ASC) in post-menopausal women. Post-menopausal women (n = 11; mean age 57 ± 4.5 years) were treated for 2 weeks, in a randomized, cross-over design, with transdermal E2 (0.15 mg) or placebo patches. Biopsies of abdominal (AB) and femoral (FEM) subcutaneous adipose tissue (SAT) were obtained after each treatment and mature adipocytes were analysed for cell size and ASC for their capacity for proliferation (growth rate), differentiation (triglyceride accumulation) and susceptibility to tumour necrosis factor alpha-induced apoptosis...
November 15, 2016: Journal of Cellular and Molecular Medicine
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