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https://www.readbyqxmd.com/read/29933377/predictors-and-trajectories-of-antibiotic-consumption-in-22-eu-countries-findings-from-a-time-series-analysis-2000-2014
#1
Maria Michela Gianino, Jacopo Lenzi, Marco Bonaudo, Maria Pia Fantini, Walter Ricciardi, Gianfranco Damiani
BACKGROUND: This study analyzes the trajectories of antibiotic consumption using different indicators of patients' socioeconomic status, category and age-group of physicians. METHODS: This study uses a pooled, cross-sectional, time series analysis. The data focus on 22 European countries from 2000 to 2014 and were obtained from the European Center for Disease and Control, Organization for Economic Co-operation and Development, Eurostat and Global Economic Monitor...
2018: PloS One
https://www.readbyqxmd.com/read/29933269/high-fidelity-simulation-nurse-training-reduces-unplanned-interruption-of-continuous-renal-replacement-therapy-sessions-in-critically-ill-patients-the-simher-randomized-controlled-trial
#2
Pierre Lemarie, Solenne Husser Vidal, Soizic Gergaud, Xavier Verger, Emmanuel Rineau, Jerome Berton, Elsa Parot-Schinkel, Jean-François Hamel, Sigismond Lasocki
BACKGROUND: Although continuous renal replacement therapy (CRRT) is common, unplanned interruptions (UI) often limit its usefulness. In many units, nurses are responsible for CRRT management. We hypothesized that a nurse training program based on high-fidelity simulation would reduce the rate of interrupted sessions. METHODS: We performed a 2-phase (training and evaluation), randomized, single-center, open study: During the training phase, intensive care unit nurses underwent a 6-hour training program and were randomized to receive (intervention) or not (control) an additional high-fidelity simulation training (6 hours)...
June 20, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29933229/potentially-inappropriate-medications-in-elderly-ambulatory-patients-a-comparative-study-between-a-primary-health-care-center-and-a-community-pharmacy
#3
Luciana C Chiapella, Jorgelina Montemarani Menna, María Eugenia Mamprin
OBJECTIVE: This study aims to compare, both qualitatively and quantitatively, the medication dispensed to elderly patients in a primary health care center (PHC) and a community pharmacy (CP) in Argentina and to identify the prescription of potentially inappropriate medications (PIMs). METHODS: A cross-sectional observational study. Data were acquired from 886 prescriptions in the PHC and 2368 in the CP between February and April 2015. Dispensed medications were coded according to the Anatomical, Therapeutic, and Chemical (ATC) classification system...
June 19, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29932885/understanding-health-related-quality-of-life-in-caregivers-of-civilians-and-service-members-veterans-with-traumatic-brain-injury-establishing-the-reliability-and-validity-of-promis-mental-health-measures
#4
Noelle E Carlozzi, Robin Hanks, Rael T Lange, Tracey A Brickell D Psych, Phillip A Ianni, Jennifer A Miner, Louis M French Psy D, Michael A Kallen, Angelle M Sander
OBJECTIVE: To provide important reliability and validity data to support the use of the PROMIS Mental Health measures in caregivers of civilians or service members/veterans with traumatic brain injury (TBI). DESIGN: Patient-reported outcomes surveys administered through an electronic data collection platform. SETTING: Three TBI Model Systems rehabilitation hospitals, an academic medical center, and a military medical treatment facility. PARTICIPANTS: 560 caregivers of individuals with a documented TBI (344 civilians and 216 military) INTERVENTION: Not Applicable MAIN OUTCOME MEASURES: PROMIS Anxiety, Depression, and Anger Item Banks RESULTS: Internal consistency for all of the PROMIS Mental Health item banks was very good (all α > ...
June 19, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29932884/understanding-health-related-quality-of-life-in-caregivers-of-civilians-and-service-members-veterans-with-traumatic-brain-injury-establishing-the-reliability-and-validity-of-promis-fatigue-and-sleep-disturbance-item-banks
#5
Noelle E Carlozzi, Phillip A Ianni, David S Tulsky, Tracey A Brickell, Rael T Lange, Louis M French, David Cella, Michael A Kallen, Jennifer A Miner, Anna L Kratz
OBJECTIVE: To examine the reliability and validity of Patient Reported Outcomes Measurement Information System (PROMIS) measures of sleep disturbance and fatigue in TBI caregivers and to determine the severity of fatigue and sleep disturbance in these caregivers. DESIGN: Cross-sectional survey data collected through an online data capture platform. SETTING: Four rehabilitation hospitals and Walter Reed National Military Medical Center. PARTICIPANTS: Caregivers (N=560) of civilians (n=344) and service member/veterans (n=216) with TBI...
June 19, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29932731/clinical-implications-of-lipohypertrophy-among-people-with-type-1-diabetes-in-india
#6
Sunil S Gupta, Kavita S Gupta, Sachin S Gathe, Parvinder Bamrah, Shlok S Gupta
BACKGROUND: Lipohypertrophy (LH) at insulin injection sites is a common but preventable complication in type 1 diabetes mellitus (T1DM). We evaluated the prevalence, contributing risk factors, and consequences of LH, specifically the glycemic variability (GV) among T1DM patients. METHODS: This is a cross-sectional study conducted at a tertiary care center in India, wherein 139 subjects with T1DM were randomly selected and evaluated for the presence of LH through visual and palpation examinations...
June 22, 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29932570/the-patient-centered-medical-home-model-and-diabetes-outcomes-an-integrative-literature-review
#7
Glenmore Hendricks, Andrew P Corr, Annie P Odell, Joy R Goebel
The purpose of this integrative review was to synthesize the existing evidence on diabetes care within a Patient-Centered Medical Home (PCMH) model to evaluate its effectiveness on quality outcomes. Literature published in English between 2005 and 2015 was searched using thefollowing keywords: PCMH and diabetes, comprehensive care, care coordination, patient-centered care, quality and safety, and accessible care. The following databases were searched: Cumulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, Cochrane Review, Academic Premier (EBSCO), and Psych INFO...
July 2017: Journal of National Black Nurses' Association: JNBNA
https://www.readbyqxmd.com/read/29932430/dynamic-data-monitoring-improves-predictive-analytics-for-failed-extubation-in-the-icu
#8
Jessica Keim-Malpass, Kyle B Enfield, James Forrest Calland, Douglas E Lake, Matthew T Clark
Predictive analytics monitoring that informs clinicians of the risk for failed extubation would help minimize both the duration of mechanical ventilation and the risk of emergency re-intubation in ICU patients. We hypothesized that dynamic monitoring of cardiorespiratory data, vital signs, and lab test results would add information to standard clinical risk factors. To develop predictive analytic models for patients who failed extubation in critical care settings in an academic medical center using standard and novel risk factors...
June 22, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29932412/attitudes-of-nephrologists-towards-intensified-hemodialysis
#9
Julia Thumfart, Steffen Wagner, Anuradha Jayanti, Dominik Müller, Wolfgang Pommer
AIMS: Intensified hemodialysis (HD) programs have been developed to overcome the shortcomings of conventional HD. However, there are no data on the implementation of intensified HD programs into routine care. Therefore, we investigated the attitude of nephrologists towards intensified HD, its penetrance into clinical practice, and barriers to implementation. MATERIALS AND METHODS: We performed an online survey within the German Society of Nephrology on the beliefs and attitudes towards intensified HD...
June 22, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29932382/microsurgical-treatment-of-unruptured-middle-cerebral-artery-aneurysms-a-large-contemporary-experience
#10
Eric S Nussbaum, Michael T Madison, James K Goddard, Jeffrey P Lassig, Kevin M Kallmes, Leslie A Nussbaum
OBJECTIVE Advances in endovascular therapy for the treatment of middle cerebral artery (MCA) aneurysms have led to scrutiny of its benefits compared with microsurgical repair. To provide information regarding complication rates and outcomes, the authors reviewed the results of a large series of unruptured MCA aneurysms treated with open microsurgery. METHODS The authors included all patients who underwent surgical repair of an unruptured MCA aneurysm between 1997 and 2015. All surgical procedures, including clipping, wrapping, bypass, and parent artery occlusion, were performed by a single neurosurgeon...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29932379/safety-and-efficacy-of-a-novel-neurosurgical-enhanced-recovery-after-surgery-protocol-for-elective-craniotomy-a-prospective-randomized-controlled-trial
#11
Yuan Wang, Bolin Liu, Tianzhi Zhao, Binfang Zhao, Daihua Yu, Xue Jiang, Lin Ye, Lanfu Zhao, Wenhai Lv, Yufu Zhang, Tao Zheng, Yafei Xue, Lei Chen, Eric Sankey, Long Chen, Yingxi Wu, Mingjuan Li, Lin Ma, Zhengmin Li, Ruigang Li, Juan Li, Jing Yan, Shasha Wang, Hui Zhao, Xude Sun, Guodong Gao, Yan Qu, Shiming He
OBJECTIVE Although enhanced recovery after surgery (ERAS) programs have gained acceptance in various surgical specialties, no established neurosurgical ERAS protocol for patients undergoing elective craniotomy has been reported in the literature. Here, the authors describe the design, implementation, safety, and efficacy of a novel neurosurgical ERAS protocol for elective craniotomy in a tertiary care medical center located in China. METHODS A multidisciplinary neurosurgical ERAS protocol for elective craniotomy was developed based on the best available evidence...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29932220/racial-and-ethnic-disparities-in-travel-for-head-and-neck-cancer-treatment-and-the-impact-of-travel-distance-on-survival
#12
Evan M Graboyes, Mark A Ellis, Hong Li, John M Kaczmar, Anand K Sharma, Eric J Lentsch, Terry A Day, Chanita Hughes Halbert
BACKGROUND: Patients who travel a long distance (≥50 miles) for cancer care have improved outcomes. However, to the authors' knowledge, the prevalence of long travel distances for treatment by patients with head and neck squamous cell carcinoma (HNSCC), and the effect of travel distance on overall survival (OS), remains unknown. METHODS: The authors used the National Cancer Data base from 2004 through 2013 to identify patients with HNSCC undergoing definitive treatment...
June 22, 2018: Cancer
https://www.readbyqxmd.com/read/29931579/hypoglycemia-among-patients-with-type-2-diabetes-epidemiology-risk-factors-and-prevention-strategies
#13
REVIEW
Richard Silbert, Alejandro Salcido-Montenegro, Rene Rodriguez-Gutierrez, Abdulrahman Katabi, Rozalina G McCoy
PURPOSE OF REVIEW: Hypoglycemia is the most common and often treatment-limiting serious adverse effect of diabetes therapy. Despite being potentially preventable, hypoglycemia in type 2 diabetes incurs substantial personal and societal burden. We review the epidemiology of hypoglycemia in type 2 diabetes, discuss key risk factors, and introduce potential prevention strategies. RECENT FINDINGS: Reported rates of hypoglycemia in type 2 diabetes vary widely as there is marked heterogeneity in how hypoglycemia is defined, measured, and reported...
June 21, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29931490/the-impact-of-automated-screening-with-edmonton-symptom-assessment-system-esas-on-health-related-quality-of-life-supportive-care-needs-and-patient-satisfaction-with-care-in-268-ambulatory-cancer-patients
#14
Benjamin D Diplock, Kaitlin M C McGarragle, Willem A Mueller, Sana Haddad, Rachel Ehrlich, Dong-Hyun A Yoon, Xingshan Cao, Yaseen Al-Allaq, Paul Karanicolas, Margaret I Fitch, Jeff Myers, Alex J Mitchell, Janet W M Ellis
PURPOSE: We aimed to assess the impact of implementing Edmonton Symptom Assessment System (ESAS) screening on health-related quality of life (HRQoL) and patient satisfaction with care (PSC) in ambulatory oncology patients. ESAS is now a standard of care in Ontario cancer centers, with the goal of improving symptom management in cancer patients, yet few studies examine impact of ESAS on patient outcomes. METHODS: We compared ambulatory oncology patients who were not screened prior to ESAS site implementation (2011-2012), to a similar group who were screened using ESAS after site implementation (2012-2013), to examine between-group differences in patient HRQoL, PSC outcomes, and supportive care needs (Supportive Care Service Survey)...
June 21, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29931369/frostbite-in-the-united-states-an-examination-of-the-national-burn-repository-and-national-trauma-data-bank
#15
Rachel M Nygaard, Frederick W Endorf
Frostbite is a form of thermal injury that can have devastating consequences for patients, including digit amputations and sometimes more proximal amputations. To the best of the authors' knowledge, no one has determined national characteristics of frostbite patients, nor the prevalence of these diagnostic and therapeutic modalities. This is the first look at nationwide trends in the treatment of frostbite in the United States. Patients with frostbite injury were identified in the National Trauma Data Bank (NTDB) and National Burn Repository (NBR)...
December 6, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29931106/comparison-of-alere-i-strep-a-rapid-molecular-assay-with-rapid-antigen-testing-and-culture-in-a-pediatric-outpatient-setting
#16
Elizabeth P Weinzierl, Robert C Jerris, Mark D Gonzalez, Julie A Piccini, Beverly B Rogers
Objectives: Group A Streptococcus (GAS) is the most common bacterial cause of pediatric acute pharyngitis, and its quick identification is important for subsequent treatment. We sought to determine whether molecular GAS-based testing can successfully replace GAS antigen testing and subsequent culture in a pediatric urgent care center. Methods: We tested 160 patient oropharyngeal samples by a rapid antigen GAS test, the Alere i Strep A test, and throat culture in a pediatric urgent care setting and calculated basic statistical metrics...
June 19, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29931071/impact-of-prehospital-hypothermia-on-the-outcomes-of-severely-burned-patients
#17
Denis Ehrl, Paul I Heidekrueger, Johannes Rubenbauger, Milomir Ninkovic, P Niclas Broer
When treating burn injuries, to date, there still remains significant disagreement whether presence of hypothermia (HT) on burn centers' intensive care unit (BICU) admission improves or worsens outcomes. The presented single burn center experiences set out to further evaluate the incidence, cause, and potential effects of HT on outcomes in severely burned patients. Between January 2015 and February 2017, 142 severely burned patients were admitted to a BICU. Temperature at BICU admission of <36.0°C was defined as HT and ≥36...
February 2, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29930972/the-spectrum-of-movement-disorders-in-childhood-onset-lysosomal-storage-diseases
#18
Darius Ebrahimi-Fakhari, Clara Hildebrandt, Peter E Davis, Lance H Rodan, Irina Anselm, Olaf Bodamer
Background: Movement disorders are a significant clinical problem in lysosomal storage diseases (LSD) and account for substantial morbidity. The spectrum of movement disorders in childhood-onset LSD, however, remains poorly defined. Objectives: To define the spectrum of movement disorders in a well-characterized cohort of children with LSD. Methods: A retrospective chart review at a single tertiary care center (Boston Children's Hospital, Boston, MA, USA)...
March 2018: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/29930967/integrating-social-determinants-of-health-into-primary-care-clinical-and-informational-workflow-during-care-transitions
#19
Sharon Hewner, Sabrina Casucci, Suzanne Sullivan, Francine Mistretta, Yuqing Xue, Barbara Johnson, Rebekah Pratt, Li Lin, Chester Fox
Context: Care continuity during transitions between the hospital and home requires reliable communication between providers and settings and an understanding of social determinants that influence recovery. Case Description: The coordinating transitions intervention uses real time alerts, delivered directly to the primary care practice for complex chronically ill patients discharged from an acute care setting, to facilitate nurse care coordinator led telephone outreach...
July 4, 2017: EGEMS
https://www.readbyqxmd.com/read/29930774/histopathologic-analysis-of-gingival-lesions-a-20-year-retrospective-study-at-one-academic-dental-center
#20
Jazia A Alblowi, Nada O Binmadi
Background: The gingiva is part of the periodontium supporting structures surrounding the teeth and commonly involved in gingival and periodontal conditions. Assessing the distribution of gingival lesions is important for evaluating the prevalence of periodontal disease in the population to optimize the oral health care services. The purpose of this study is to report the frequency and distribution of gingival lesions biopsied from 1996-2016. Material and Methods: This cross-sectional retrospective study retrieved data from all gingival lesions biopsied from 1996-2016 and sent to the King Abdulaziz University Dental Hospital oral pathology laboratory...
June 2018: Journal of Clinical and Experimental Dentistry
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