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https://www.readbyqxmd.com/read/29781373/subliminal-gender-stereotypes-who-can-resist
#1
Jolien A van Breen, Russell Spears, Toon Kuppens, Soledad de Lemus
We examine women's responses to subliminal gender stereotypes, that is, stereotypes present outside conscious awareness. Previous research suggests that subtle stereotypes elicit acceptance and assimilation, but we predict that subliminal exposure to gender stereotypes will trigger resistance in some women. Specifically, we expect resistance to occur among women who are relatively strongly identified with feminists, but not with the broader group of women. We predict that resistance takes the form of persistence in stereotypically masculine domains and (implicit) in-group bias...
May 1, 2018: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/29777402/a-national-study-of-the-use-of-asymptomatic-systemic-imaging-for-surveillance-following-breast-cancer-treatment-aft-01
#2
Jessica R Schumacher, Heather B Neuman, George J Chang, Benjamin D Kozower, Stephen B Edge, Menggang Yu, David J Vanness, Yajuan Si, Elizabeth A Jacobs, Amanda B Francescatti, Patricia A Spears, Jeffrey Havlena, Taiwo Adesoye, Daniel McKellar, David Winchester, Elizabeth S Burnside, Caprice C Greenberg
BACKGROUND: Although not guideline recommended, studies suggest 50% of locoregional breast cancer patients undergo systemic imaging during follow-up, prompting its inclusion as a Choosing Wisely measure of potential overuse. Most studies rely on administrative data that cannot delineate scan intent (prompted by signs/symptoms vs. asymptomatic surveillance). This is a critical gap as intent is the only way to distinguish overuse from appropriate care. OBJECTIVE: Our aim was to assess surveillance systemic imaging post-breast cancer treatment in a national sample accounting for scan intent...
May 17, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29765259/shadowing-emergency-medicine-residents-by-medical-education-specialists-to-provide-feedback-on-non-medical-knowledge-based-acgme-sub-competencies
#3
Anna L Waterbrook, Karen C Spear Ellinwood, T Gail Pritchard, Karen Bertels, Ariel C Johnson, Alice Min, Lisa R Stoneking
Objective: Non-medical knowledge-based sub-competencies (multitasking, professionalism, accountability, patient-centered communication, and team management) are challenging for a supervising emergency medicine (EM) physician to evaluate in real-time on shift while also managing a busy emergency department (ED). This study examines residents' perceptions of having a medical education specialist shadow and evaluate their nonmedical knowledge skills. Methods: Medical education specialists shadowed postgraduate year 1 and postgraduate year 2 EM residents during an ED shift once per academic year...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29765160/author-correction-effects-of-adolescent-alcohol-consumption-on-the-brain-and-behaviour
#4
Linda P Spear
In the initially published version of this article, the following sentence was incorrect: "Studies that have compared equivalent exposures to alcohol in adolescent and adult animals have found that the effects of alcohol exposure during adolescence are generally not evident or are less pronounced than after comparable alcohol exposure in adulthood". The sentence should have read: "Studies that have compared equivalent exposures to alcohol in adolescent and adult animals have found that the effects of alcohol exposure during adulthood are generally not evident or are less pronounced than after comparable alcohol exposure in adolescence"...
May 15, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29752719/hbv-suppresses-zhx2-expression-to-promote-proliferation-of-hcc-through-mir-155-activation
#5
Xiaojia Song, Siyu Tan, Zhuanchang Wu, Leiqi Xu, Zehua Wang, Yong Xu, Tixiao Wang, Chengjiang Gao, Yaoqin Gong, Xiaohong Liang, Lifen Gao, Brett T Spear, Chunhong Ma
Initiation of hepatocellular carcinoma (HCC) by chronic hepatitis B virus (HBV) infection is a complex process that includes both oncogene activation and tumor suppressor inhibition. The HBV X (HBx) protein has an important and complex role in processes leading to HCC. We previously identified the mammalian Zinc fingers and homeoboxes 2 (ZHX2) gene as an HCC-associated tumor suppressor gene. In the present study, we investigated whether the oncogenic properties of HBV and, more specifically, HBx, involved ZHX2 silencing...
May 11, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29746389/effect-of-sand-on-knee-load-during-a-single-leg-jump-task-implications-for-injury-prevention-and-rehabilitation-programs
#6
Mark C Richardson, Sinead Murphy, Tom Macpherson, Bryan English, Iain Spears, Paul Chesterton
Richardson, MC, Murphy, S, Macpherson, T, English, B, Spears, I, and Chesterton, P. Effect of sand on knee load during a single-leg jump task: implications for injury prevention and rehabilitation programs. J Strength Cond Res XX(X): 000-000, 2018-The purpose of the study was to determine potential differences in landing strategies and subsequent joint loads at the knee (knee abduction moment [KAM], anterior-posterior [AP] tibial translation, and total knee shear force) when jumping onto sand and firm ground from both a level surface and a 30-cm height...
May 7, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29742668/effects-of-the-affordable-care-act-on-young-women-with-gynecologic-cancers
#7
Anna Jo Bodurtha Smith, Amanda N Fader
OBJECTIVE: To evaluate the effects of the dependent coverage mandate of the 2010 Affordable Care Act (ACA) on insurance status, stage at diagnosis, and receipt of fertility-sparing treatment among young women with gynecologic cancer. METHODS: We used a difference-in-differences design to assess insurance status, stage at diagnosis (stage I-II vs III-IV), and receipt of fertility-spearing treatment before and after the 2010 ACA among young women aged 21-26 years vs women aged 27-35 years...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29740184/introduction-of-triggers-for-palliative-care-consultation-improves-utilization-and-satisfaction-within-a-level-four-nicu
#8
Linda T Nguyen, David B Cooperberg, Michael L Spear
OBJECTIVE: We sought to explore the beliefs regarding palliative care team utilization, as well as increase consultation and awareness of the palliative care team's role in the NICU. STUDY DESIGN: The study design in this Level 4 NICU included observational time series with multiple planned sequential interventions. Medical chart review was conducted to determine eligibility, and statistical process control charts were used to show performance over time. RESULTS: Prior to implementation of the triggers, 26% received consultation, which increased to 46% after implementation...
May 8, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29719834/genomic-instabilities-cellular-senescence-and-aging-in-vitro-in-vivo-and-aging-like-human-syndromes
#9
REVIEW
Gabriel Lidzbarsky, Danielle Gutman, Huda Adwan Shekhidem, Lital Sharvit, Gil Atzmon
As average life span and elderly people prevalence in the western world population is gradually increasing, the incidence of age-related diseases such as cancer, heart diseases, diabetes, and dementia is increasing, bearing social and economic consequences worldwide. Understanding the molecular basis of aging-related processes can help extend the organism's health span, i.e., the life period in which the organism is free of chronic diseases or decrease in basic body functions. During the last few decades, immense progress was made in the understanding of major components of aging and healthy aging biology, including genomic instability, telomere attrition, epigenetic changes, proteostasis, nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and intracellular communications...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29717710/bacteroides-thetaiotaomicron-generates-diverse-%C3%AE-mannosidase-activities-through-subtle-evolution-of-a-distal-substrate-binding-motif
#10
Andrew J Thompson, Richard J Spears, Yanping Zhu, Michael D L Suits, Spencer J Williams, Harry J Gilbert, Gideon J Davies
A dominant human gut microbe, the well studied symbiont Bacteroides thetaiotaomicron (Bt), is a glyco-specialist that harbors a large repertoire of genes devoted to carbohydrate processing. Despite strong similarities among them, many of the encoded enzymes have evolved distinct substrate specificities, and through the clustering of cognate genes within operons termed polysaccharide-utilization loci (PULs) enable the fulfilment of complex biological roles. Structural analyses of two glycoside hydrolase family 92 α-mannosidases, BT3130 and BT3965, together with mechanistically relevant complexes at 1...
May 1, 2018: Acta Crystallographica. Section D, Structural Biology
https://www.readbyqxmd.com/read/29716788/aquaporin-4-and-myelin-oligodendrocyte-glycoprotein-autoantibody-status-predict-outcome-of-recurrent-optic-neuritis
#11
Jiraporn Jitprapaikulsan, John J Chen, Eoin P Flanagan, W Oliver Tobin, Jim P Fryer, Brian G Weinshenker, Andrew McKeon, Vanda A Lennon, Jacqueline A Leavitt, Jan-Mendelt Tillema, Claudia Lucchinetti, B Mark Keegan, Orhun Kantarci, Cheryl Khanna, Sarah M Jenkins, Grant M Spears, Jessica Sagan, Sean J Pittock
PURPOSE: To determine the aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG) immunoglobulin G (IgG) serostatus and visual outcomes in patients with recurrent optic neuritis (rON) initially seeking treatment. DESIGN: Cross-sectional cohort study. PARTICIPANTS: The study identified patients by searching the Mayo Clinic computerized central diagnostic index (January 2000-March 2017). The 246 eligible patients fulfilled the following criteria: (1) initially seeking treatment for at least 2 consecutive episodes of optic neuritis (ON) and (2) serum available for testing...
April 28, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29714525/patient-drug-safety-reporting-diabetes-patients-perceptions-of-drug-safety-and-how-to-improve-reporting-of-adverse-events-and-product-complaints
#12
Puja Patel, David Spears, Betina Østergaard Eriksen, Karsten Lollike, Michael Sacco
BACKGROUND: Global health care manufacturer Novo Nordisk commissioned research regarding awareness of drug safety department activities and potential to increase patient feedback. Objectives were to examine patients' knowledge of pharmaceutical manufacturers' responsibilities and efforts regarding drug safety, their perceptions and experiences related to these efforts, and how these factors influence their thoughts and behaviors. Data were collected before and after respondents read a description of a drug safety department and its practices...
March 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29691859/survey-of-rabies-vaccination-status-of-queensland-veterinarians-and-veterinary-students
#13
D Mendez, L Foyle, R Cobbold, R Speare
BACKGROUND: To determine the rabies vaccination status of Queensland veterinarians and veterinary students and their perception of zoonotic risk from Australian bat lyssavirus (ABLV). DESIGN: Cross-sectional questionnaire surveys. METHODS: Questionnaires were sent by post in 2011 to veterinary surgeons registered in Queensland, to final-year veterinary students at James Cook University via SurveyMonkey® in 2013 and to final-year veterinary students at James Cook University and University of Queensland via SurveyMonkey® in 2014...
May 2018: Australian Veterinary Journal
https://www.readbyqxmd.com/read/29687077/efficacy-and-outcomes-of-intrathecal-analgesia-as-part-of-an-enhanced-recovery-pathway-in-colon-and-rectal-surgical-patients
#14
Amit Merchea, Jenna K Lovely, Adam K Jacob, Dorin T Colibaseanu, Scott R Kelley, Kellie L Mathis, Grant M Spears, Marianne Huebner, David W Larson
Purpose: Multimodal analgesia is an essential component of an enhanced recovery pathway (ERP). An ERP that includes the use of single-injection intrathecal analgesia (IA) has been shown to decrease morbidity and cost and shorten length of stay (LOS). Limited data exist on safety, feasibility, and the optimal IA regimen. Our objective was to characterize the efficacy, safety, and feasibility of IA within an ERP in a cohort of colorectal surgical patients. Methods: We performed a retrospective review of all consecutive patients aged ≥ 18 years who underwent open or minimally invasive colorectal surgery from October 2012 to December 2013...
2018: Surgery Research and Practice
https://www.readbyqxmd.com/read/29686207/a-new-and-four-known-species-of-diphtherophora-nematoda-diphtherophoridae-from-iran-with-a-diagnostic-compendium-of-its-species
#15
Reza Ghaderi, Leila Kashi, Hossein Mirbabaei Karani, Akbar Karegar
A new and four known species of the genus Diphtherophora-D. geraerti sp. n., D. caudata, D. obesa, D. perplexans and D. tenera-were collected and identified from different plants and localities in Iran. Morphological and morphometric characters of Diphtherophora geraerti sp. n. are compared with those of closely-related species, including D. siddiqii, D. brevicollis, D. lata, D. obesa, D. citri, D. vasilevi and D. vitoshae. Females of the new species have a head continuous with the body contour, spear 11-14 µm in length, rod-shaped spermatozoa and conical tail with bluntly rounded to hemispherical terminus...
December 18, 2017: Zootaxa
https://www.readbyqxmd.com/read/29681200/cost-analysis-of-plasma-derived-factor-viii-von-willebrand-factor-vs-recombinant-factor-viii-for-treatment-of-previously-untreated-patients-with-severe-hemophilia-a-in-the-united-states
#16
Ellis J Neufeld, Robert F Sidonio, Ken O'Day, M Chris Runken, Kellie Meyer, Jeffrey Spears
BACKGROUND: Inhibitor development to factor VIII (FVIII) hemophilia therapy results in increased complications and substantial economic costs. The SIPPET study, the first randomized controlled trial to compare the immunogenicity of plasma-derived FVIII (pdFVIII)/von Willebrand factor (VWF) and recombinant-DNA-derived FVIII (rFVIII), demonstrated higher inhibitor rates in previously untreated patients (PUPs) treated with rFVIII than in PUPs treated with pdFVIII/VWF. OBJECTIVE: To quantify the economic impact of treating PUPs with pdFVIII/VWF versus rFVIII...
April 21, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29669133/uncovering-susceptibility-risk-to-online-deception-in-aging
#17
Natalie C Ebner, Donovan M Ellis, Tian Lin, Harold A Rocha, Huizi Yang, Sandeep Dommaraju, Adam Soliman, Damon L Woodard, Gary R Turner, R Nathan Spreng, Daniela S Oliveira
Objectives: Fraud in the aged is an emerging public health problem. An increasingly common form of deception is conducted online. However, identification of cognitive and socioemotional risk factors has not been undertaken yet. In this endeavor, this study extended previous work suggesting age effects on susceptibility to online deception. Methods: Susceptibility was operationalized as clicking on the link in simulated spear-phishing emails that young (18-37 years), young-old (62-74 years), and middle-old (75-89 years) Internet users received, without knowing that the emails were part of the study...
April 13, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29668510/gauze-impregnated-with-quaternary-ammonium-salt-reduces-bacterial-colonization-of-surgical-drains-after-breast-reconstruction
#18
Amy L Strong, Emily T Wolfe, Nina Shank, Abigail E Chaffin, David A Jansen
Surgical site infection after breast reconstruction is associated with increased length of hospital stay, readmission rates, cost, morbidity, and mortality. Identifying methods to reduce surgical site infection without the use of antibiotics may be beneficial at reducing antimicrobial resistance, reserving the use of antibiotics for more severe cases. Quaternary ammonium salts have previously been shown to be a safe and effective antimicrobial agent in the setting of in vitro and in vivo animal experiments...
April 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29663352/prognostic-value-of-pathological-node-status-after-neoadjuvant-radiotherapy-for-rectal-cancer
#19
E Duchalais, T Glyn Mullaney, G M Spears, S R Kelley, K Mathis, W S Harmsen, D W Larson
BACKGROUND: The prognostic value of pathological lymph node status following neoadjuvant radiotherapy (ypN) remains unclear. This study was designed to determine whether ypN status predicted overall survival. METHODS: Patients with locally advanced rectal adenocarcinoma who underwent neoadjuvant long-course radiation between 2005 and 2014 were identified from the National Cancer Data Base, and divided into ypN0, ypN1 and ypN2 groups. The primary outcome was overall survival...
April 17, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29644797/altered-gastrointestinal-motility-involving-autoantibodies-in-the-experimental-autoimmune-encephalomyelitis-model-of-multiple-sclerosis
#20
E T Spear, E A Holt, E J Joyce, M M Haag, S M Mawe, G W Hennig, B Lavoie, A M Applebee, C Teuscher, G M Mawe
BACKGROUND: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that, in addition to motor, sensory, and cognitive symptoms, also causes constipation, which is poorly understood. Here, we characterize gastrointestinal (GI) dysmotility in the experimental autoimmune encephalomyelitis (EAE) mouse model of MS and evaluate whether autoantibodies target the enteric nervous system (ENS) and cause dysmotility. METHODS: EAE was induced in male SJL and B6 mice...
April 11, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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