Rachel K Hopper, Steven H Abman, Eleni G Elia, Catherine M Avitabile, Delphine Yung, Mary P Mullen, Eric D Austin, Angela Bates, Stephanie S Handler, Jeffrey A Feinstein, D Dunbar Ivy, John P Kinsella, Kenneth D Mandl, J Usha Raj, Lynn A Sleeper
OBJECTIVE: To characterize distinct comorbidities, outcomes, and treatment patterns in children with Down syndrome and pulmonary hypertension in a large, multicenter pediatric pulmonary hypertension registry. STUDY DESIGN: We analyzed data from the Pediatric Pulmonary Hypertension Network (PPHNet) Registry, comparing demographic and clinical characteristics of children with Down syndrome and children without Down syndrome. We examined factors associated with pulmonary hypertension resolution and a composite outcome of pulmonary hypertension severity in the cohort with Down syndrome...
January 2023: Journal of Pediatrics