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Medical Allergy

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https://www.readbyqxmd.com/read/28633739/autoimmune-progesterone-dermatitis-presenting-as-fixed-drug-eruption-a-case-report
#1
Raya Mokhtari, Mozhdeh Sepaskhah, Fatemeh Sari Aslani, Ladan Dastgheib
Autoimmune progesterone dermatitis (APD) is a rare disorder characterized by periodic skin lesions that erupt during the luteal phase of the menstrual cycle. Clinical manifestations of APD is caused by an unusual allergy to progesterone and has a wide range of clinical manifestations from eczema and urticaria to angioedema and erythema multiforme. A 46-year-old woman described recurrent, round erythematous plaques on the lower lip, both forearms and buttocks. These skin eruptions waxed and waned for 10 months, reoccurring 3-4 days before menstruation...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28627716/a-cherry-seed-derived-spice-mahleb-is-recognized-by-anti-almond-antibodies-including-almond-allergic-patient-ige
#2
Kyle A Noble, Changqi Liu, Shridhar K Sathe, Kenneth H Roux
There are a number of examples of immunologic cross-reactivity elicited by pollens, fruits, seeds, and nuts of closely related plant species. Such cross-reactivity is of particular concern for patients with food allergies. In this report, we investigated a spice (mahleb) that is prepared from the kernel of the St. Lucie cherry, Prunus mahaleb, for cross-reactivity with almond (Prunus dulcis), using enzyme-linked immunosorbent assay (ELISA) and Western blot. Almond and mahleb are members of the same genus. Cross-reactivity between the mahleb and almond was demonstrated by reaction of cherry and almond kernel protein extracts with antibodies raised against almond proteins...
June 19, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28626380/clinical-and-pathologic-remission-of-pediatric-ulcerative-colitis-with-serum-derived-bovine-immunoglobulin-added-to-the-standard-treatment-regimen
#3
Rachelle A Soriano, Asuncion G Ramos-Soriano
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is particularly troublesome for pediatric patients, as current therapeutic options consist of biologic agents and steroids which alter the immune response and have the harmful side effect of leaving the patient more susceptible to opportunistic infections and eventual surgery. Another option for therapy exists in the form of serum-derived bovine immunoglobulin/protein isolate (SBI), the key ingredient in a medical food, EnteraGam®. The FDA has reviewed the safety of SBI and issued a no challenge letter to the generally recognized as safe (GRAS) findings for this medical food...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28616043/angioedema-suppressed-by-a-combination-of-anti-histamine-and-leukotriene-modifier
#4
Brendan N Wong, Peter Vadas
RATIONALE: Angioedema without co-existent urticaria is due to a limited number of causes, including hereditary and acquired C1 esterase inhibitor deficiency, drug-induced angioedema or idiopathic histaminergic or non-histaminergic angioedema. We describe a cohort of patients with recurrent angioedema whose clinical features and response to medications are distinct from the causes above. METHODS: Patients were accrued retrospectively from an academic allergy practice between 2007 and 2014...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28614101/clinical-characteristics-of-allergy-to-hymenoptera-stings
#5
Nualanong Visitsunthorn, Teera Kijmassuwan, Kittipos Visitsunthorn, Panchama Pacharn, Orathai Jirapongsananuruk
OBJECTIVE: The purpose of this study was to evaluate the clinical characteristics of allergy to stings from the Hymenoptera order of insects in a hospital in Thailand. METHODS: A descriptive retrospective analytical study was carried out in inpatients and outpatients suffering from Hymenoptera stings from 2009 to 2013 in Siriraj Hospital. RESULTS: Medical records of 386 patients with an allergy to Hymenoptera stings were evaluated. Anaphylaxis was more common in patients younger than 15 years, who comprised 22...
June 13, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28606570/comparing-nutritional-requirements-provision-and-intakes-among-patients-prescribed-therapeutic-diets-in-hospital-an-observational-study
#6
Megan Rattray, Ben Desbrow, Shelley Roberts
OBJECTIVE: Nutrition is an important part of recovery for hospitalized patients. The aim of this study was to assess the nutritional adequacy of meals provided to and consumed by patients prescribed a therapeutic diet. METHODS: Patients (N = 110) prescribed a therapeutic diet (texture-modified, low-fiber, oral fluid, or food allergy or intolerance diets) for medical or nutritional reasons were recruited from six wards of a tertiary hospital. Complete (24-h) dietary provisions and intakes were directly observed and analyzed for energy (kJ) and protein (g) content...
July 2017: Nutrition
https://www.readbyqxmd.com/read/28605260/cellular-therapies-for-treatment-of-radiation-injury-report-from-a-nih-niaid-and-irsn-workshop
#7
Andrea L DiCarlo, Radia Tamarat, Carmen I Rios, Marc Benderitter, Christine W Czarniecki, Theresa C Allio, Francesca Macchiarini, Bert W Maidment, Jean-Rene Jourdain
In recent years, there has been increasing concern over the possibility of a radiological or nuclear incident occurring somewhere in the world. Intelligence agencies frequently report that terrorist groups and rogue nations are seeking to obtain radiological or nuclear weapons of mass destruction. In addition, there exists the real possibility that safety of nuclear power reactors could be compromised by natural (such as the tsunami and subsequent Fukushima accident in Japan in March, 2011) or accidental (Three Mile Island, 1979 and Chernobyl, 1986) events...
June 12, 2017: Radiation Research
https://www.readbyqxmd.com/read/28604832/insects-and-associated-arthropods-analyzed-during-medicolegal-death-investigations-in-harris-county-texas-usa-january-2013-april-2016
#8
Michelle R Sanford
The application of insect and arthropod information to medicolegal death investigations is one of the more exacting applications of entomology. Historically limited to homicide investigations, the integration of full time forensic entomology services to the medical examiner's office in Harris County has opened up the opportunity to apply entomology to a wide variety of manner of death classifications and types of scenes to make observations on a number of different geographical and species-level trends in Harris County, Texas, USA...
2017: PloS One
https://www.readbyqxmd.com/read/28603870/advice-about-infant-feeding-for-allergy-prevention-a-confusing-picture-for-australian-consumers
#9
Merryn J Netting, Katrina J Allen
AIM: Early feeding plays an important role in programming the immune system, particularly the risk of food allergy. There are many infant feeding guides published for consumers available in Australia, with most based on the National Health and Medical Research Council (NHMRC) 2012 Infant Feeding Guidelines for Health Workers and the Australasian Society of Clinical Immunology and Allergy (ASCIA) Infant Feeding Advice for allergy prevention. We sought to compare allergy-specific content of infant feeding educational material written for parents with these two documents...
June 12, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28602101/expert-panel-on-practice-patterns-in-the-management-of-cow-s-milk-protein-allergy-and-associated-economic-burden-of-disease-on-health-service-in-turkey
#10
Bulent Enis Sekerel, Oznur Seyhun
AIMS: To evaluate practice patterns in the management of cow's milk protein allergy (CMPA) and associated economic burden of disease on health service in Turkey. MATERIALS AND METHODS: This study was based on experts' views on the practice patterns in management of CMPA manifesting with either proctocolitis or eczema symptoms and thereby to estimate economic burden of CMPA. Practice patterns were determined via patient flow charts developed by experts using modified Delphi method for CMPA presented with proctocolitis and eczema...
June 12, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28602024/self-diagnosed-drug-allergies-the-belief-of-patients
#11
Arnaud Jannic, Amandine Servy, Xavier Chevalier, Audrey Colin, Olivier Chosidow, Saskia Ingen-Housz-Oro, Pierre Wolkenstein
The term of "drug allergy" (DA) may include true hypersensitivity or non-allergic reactions. The rate of self-reporting DA ranges from 4.7% to 11% regardless of age. When patients report a DA, the medical team often decides a full and definitive elimination of the incriminated drug from future therapy, which deeply affects medical care. This article is protected by copyright. All rights reserved.
June 11, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28599028/transitioning-the-allergy-immunology-patient-from-childhood-to-adulthood
#12
Flavia C L Hoyte
Allergic disorders and immunodeficiencies are generally chronic and even lifelong conditions, often changing over time, making the cautious transition of care from childhood to adulthood particularly important. Many, but not all, patients can continue to receive their care from the same physician as they transition through adolescence and emerging adulthood, made possible because allergy/immunology training programs require cross-training in the care of both pediatric and adult patients. Although keeping the same physician makes the transition easier for many allergy/immunology patients, even these patients face psychosocial issues unique to adolescents and emerging adults, including increased autonomy, risk-taking behavior, and medical self-management...
June 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28589859/integrative-information-theoretic-network-analysis-for-genome-wide-association-study-of-aspirin-exacerbated-respiratory-disease-in-korean-population
#13
Sehee Wang, Hyun-Hwan Jeong, Dokyoon Kim, Kyubum Wee, Hae-Sim Park, Seung-Hyun Kim, Kyung-Ah Sohn
BACKGROUND: Aspirin Exacerbated Respiratory Disease (AERD) is a chronic medical condition that encompasses asthma, nasal polyposis, and hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs. Several previous studies have shown that part of the genetic effects of the disease may be induced by the interaction of multiple genetic variants. However, heavy computational cost as well as the complexity of the underlying biological mechanism has prevented a thorough investigation of epistatic interactions and thus most previous studies have typically considered only a small number of genetic variants at a time...
May 24, 2017: BMC Medical Genomics
https://www.readbyqxmd.com/read/28587353/clinical-analysis-of-the-effect-of-anti-allergy-treatment-on-pocket-related-complications-following-pacemaker-implantation
#14
Yang Bai, Jialin Duan, Lin Wang, Rong Bai, Li Lin
A total number of 339 patients who received a pacemaker implantation between June 2012 and June 2014 at Tongji Hospital of Tongji Medical College (Wuhan, China) were investigated in the present study. The aims of the present study were to explore the risk factors of pocket hematoma following pacemaker implantation, and to analyze the effect of anti-allergy treatment on pocket-related complications following pacemaker implantation. Predictors of hematoma occurrence were determined and analyzed via a Chi-square test...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28578908/prospective-evaluation-of-electronic-medical-record-penicillin-allergy-documentation-at-a-tertiary-community-teaching-hospital
#15
Mary L Staicu, Matthew Plakosh, Allison Ramsey
No abstract text is available yet for this article.
May 31, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28578324/eppikajutsuto-protects-against-food-allergy-induced-by-ovalbumin-in-a-murine-model
#16
Teruaki Matsui, Hirotaka Yamashita, Mikito Mori, Hiroyuki Tanaka, Naoki Inagaki
BACKGROUND: Currently, there are no efficient medications available for the prevention and treatment of food allergy (FA). Herbal medicines, including traditional Japanese Kampo medicines (TJKMs), are promising therapeutic drugs. METHODS: We screened 18 TJKMs for treatment of FA symptoms in a mouse FA model induced by ovalbumin (OVA). BALB/c mice were sensitized intraperitoneally by an OVA/aluminum hydroxide gel mixture followed by 4 booster doses of oral OVA and FA symptom induction by 50 mg of OVA...
June 3, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28576636/the-treatment-of-the-pulmonary-and-extrapulmonary-manifestations-of-cystic-fibrosis
#17
Melanie Chin, Shawn D Aaron, Scott C Bell
Cystic fibrosis (CF) is a complex multisystem disease with considerable between patient variability in its manifestations and severity. In the past several decades, the range of treatments and the evidence to support their use for the pulmonary and extrapulmonary manifestations of CF have increased dramatically, contributing to the improved median survival of patients. As therapy for CF has evolved, new challenges including treatment adherence, medication intolerance and allergy, medical complications and coping with the burden of disease in the context of having a family and managing employment have arisen...
May 30, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28569128/development-of-a-student-led-ambulatory-medication-reconciliation-program-at-an-academic-institution
#18
Aimon C Miranda, Jaclyn D Cole, Melissa J Ruble, Erini S Serag-Bolos
OBJECTIVES: To integrate fourth-year student pharmacists on advanced pharmacy practice experience (APPE) rotations within several different ambulatory clinics to perform medication reconciliations and enhance interdisciplinary practice. METHODS: The study design was a descriptive, prospective multisite study among a variety of ambulatory care outpatient clinics. Student pharmacists were partnered with physicians to conduct medication reconciliations during clinic visits for 4 hours per week, with data collection from January 2016 to September 2016...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28566137/eosinophilic-esophagitis-latent-disease-in-patients-with-anaphylactic-reaction-to-cow-s-milk
#19
Adriana C Barbosa, Fábio Morato Castro, Paula Rezende Meireles, L Karla Arruda, Silvia Regina Cardoso, Jorge Kalil, Ariana C Yang
BACKGROUND: Food allergy and eosinophilic esophagitis are a substantial and evolving public health issue. Clinicians should know the relationship between these diseases and how one may predispose to the other. This can help minimize misdiagnosis. OBJECTIVE: The objective of this study was to assess esophageal eosinophilia and eosinophilic esophagitis frequency in patients with persistent cow's milk allergy and anaphylaxis manifestations. METHODS: Patients with persistent cow's milk allergy with anaphylaxis manifestations were enrolled from 2012 through 2016 at the São Paulo University Hospital, Brazil...
May 26, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28561266/sublingual-immunotherapy-provides-long-term-relief-in-allergic-rhinitis-and-reduces-the-risk-of-asthma-a-retrospective-real-world-database-analysis
#20
S Zielen, P Devillier, J Heinrich, H Richter, U Wahn
BACKGROUND: Allergy immunotherapy (AIT) is the only treatment for allergic rhinitis (AR) and/or allergic asthma (AA) with long-term efficacy. However, there are few real-life data on the progression of AR and/or AA in patients receiving AIT. OBJECTIVES: To assess the real-world, long-term efficacy of grass-pollen sublingual immunotherapy (SLIT) tablets in AR and their impact on asthma onset and progression. METHODS: In a retrospective analysis of a German longitudinal prescription database, AR patients treated with grass pollen SLIT tablets were compared with a control group not having received AIT...
May 31, 2017: Allergy
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