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https://www.readbyqxmd.com/read/27920593/slipped-capital-femoral-epiphysis-and-primary-hyperparathyroidism-a-case-report
#1
Anas A Alghamdi, Maswood M Ahmad, Mussa H Almalki
The aim of reporting this case is to highlight the association of two disorders, primary hyperparathyroidism (PHPT) and slipped capital femoral epiphysis (SCFE). They are usually seen in two different age groups and rarely together. PHPT is a rare cause of SCFE and only 10 cases have been reported in the literature worldwide. The patient in our report is a 13-year-old girl who presented to our clinic with bilateral knee pain and a waddling gait. Subsequent investigations showed that she had PHPT and SCFE with low bone mass...
2016: Clinical Medicine Insights. Endocrinology and Diabetes
https://www.readbyqxmd.com/read/27919792/the-role-of-posturography-in-assessing-the-process-of-rehabilitation-in-poststroke-patients-a-case-study
#2
Witold Rongies, Bartosz Słomka, Angelika Duczek, Włodzimierz Dolecki
Stroke is one of the most common causes of death and disability both in Poland and around the world. Each year, 250 out of 100,000 people in Europe are diagnosed with a disruption of cerebral perfusion in the form of stroke. In Poland, approximately 65,000-70,000 people are affected each year, with the incidence steadily increasing. Stroke survivors suffer from impaired cognitive and motor functions. Moreover, they exhibit severe gait pattern abnormalities, which together with balance disorders, constitute the main factors increasing the risk of falls in this patient group...
December 2, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27919671/supracondylar-femoral-osteotomy-and-knee-joint-replacement-during-the-same-surgical-procedure-in-a-type-a-haemophiliac-patient-with-knee-flexion-deformity-and-ankylosis
#3
Jose Luis Osma Rueda, Alejandra Oliveros Vargas, Cristian David Sosa
BACKGROUND: Haemophilia A is the cause of diverse musculoskeletal disorders such as ankylosis, arthritis and associated angular deformity. There are few reported cases in patients with haemophilia A in which simultaneous supracondylar femoral osteotomy and knee joint replacement has been performed to treat knee angular deformity and ankylosis. Here we present the case of an 18year old male patient, with an evolution of two years, who was unable to walk due to the presence of an untreated supracondylar fracture in the left femur and ipsilateral haemophilic arthropathy which led him to develop an ankylosis in flexion close to 70°...
December 2, 2016: Knee
https://www.readbyqxmd.com/read/27919485/the-required-coefficient-of-friction-for-evaluating-gait-alterations-in-people-with-multiple-sclerosis-during-gait
#4
Ilaria Pacifici, Manuela Galli, Ana Francisca Rozin Kleiner, Federica Corona, Giancarlo Coghe, Elisabetta Marongiu, Andrea Loi, Antonio Crisafulli, Eleonora Cocco, Maria Giovanna Marrosu, Massimiliano Pau
BACKGROUND: Required Coefficient of Friction (RCOF) is one of the most critical gait parameters associated to the occurrence of slipping in individuals affected by neurological disorders characterized by balance impairments. This study aims to calculate RCOF in people with Multiple Sclerosis (MS) on the basis of three-dimensional Gait Analysis (GA) data. METHODS: This study enrolls 22 people with MS (pwMS) who were characterized by an Expanded Disability Status Score in the range 1...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27916817/real-time-classification-of-patients-with-balance-disorders-vs-normal-subjects-using-a-low-cost-small-wireless-wearable-gait-sensor
#5
Bhargava Teja Nukala, Taro Nakano, Amanda Rodriguez, Jerry Tsay, Jerry Lopez, Tam Q Nguyen, Steven Zupancic, Donald Y C Lie
Gait analysis using wearable wireless sensors can be an economical, convenient and effective way to provide diagnostic and clinical information for various health-related issues. In this work, our custom designed low-cost wireless gait analysis sensor that contains a basic inertial measurement unit (IMU) was used to collect the gait data for four patients diagnosed with balance disorders and additionally three normal subjects, each performing the Dynamic Gait Index (DGI) tests while wearing the custom wireless gait analysis sensor (WGAS)...
November 29, 2016: Biosensors
https://www.readbyqxmd.com/read/27914848/falls-cognitive-impairment-and-gait-performance-results-from-the-good-initiative
#6
Gilles Allali, Cyrille P Launay, Helena M Blumen, Michele L Callisaya, Anne-Marie De Cock, Reto W Kressig, Velandai Srikanth, Jean-Paul Steinmetz, Joe Verghese, Olivier Beauchet
OBJECTIVES: Falls are highly prevalent in individuals with cognitive decline. The complex relationship between falls and cognitive decline (including both subtype and severity of dementia) and the influence of gait disorders have not been studied. This study aimed to examine the association between the subtype (Alzheimer disease [AD] versus non-AD) and the severity (from preclinical to moderate dementia) of cognitive impairment and falls, and to establish an association between falls and gait parameters during the course of dementia...
November 30, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27912103/gait-symmetry-in-individuals-with-and-without-developmental-coordination-disorder
#7
K Wilmut, J Gentle, A L Barnett
BACKGROUND: Symmetry between the left and right side of the body during locomotion is key in a coordinated gait cycle and is also thought to be important in terms of efficiency. Although previous studies have identified aspects of the gait cycle which are atypical in children and adults with Developmental Coordination Disorder (DCD), studies have not considered whether this could be explained by asymmetrical gait. METHOD AND PROCEDURE: The current study included 62 participants with and 62 without DCD (aged 7-34 years)...
November 29, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27908616/spinocerebellar-ataxia-15-a-phenotypic-review-and-expansion
#8
REVIEW
Philip W Tipton, Kimberly Guthrie, Audrey Strongosky, Ronald Reimer, Zbigniew K Wszolek
Spinocerebellar ataxia 15 (SCA15) is a clinically heterogeneous movement disorder characterized by the adult onset of slowly progressive cerebellar ataxia. ITPR1 is the SCA15 causative gene. However, despite numerous reports of genetically-confirmed SCA15, phenotypic uncertainty persists. We reviewed the phenotypes of 60 patients for whom SCA15 was confirmed by the presence of a genetic deletion involving ITPR1. The most prevalent symptoms were gait ataxia (88.3%), dysarthria (75.0%), nystagmus (73.3%), and limb ataxia (71...
November 10, 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/27905365/-gait-disorders-and-postural-instability-in-patients-with-an-essential-tremor
#9
S V Vasichkin, O S Levin
AIM: To study gait disorders and postural instability in patients with essential tremor (ET). MATERIAL AND METHODS: Forty patients with ET, aged from 29 to 82 years, (mean 64.2±13.0) were examined. Tandem walk, tremor, stability and stabilometry were studied. RESULTS AND CONCLUSION: A half of the patients had gait disorders and postural instability. Though these disorders were mild to moderate, they caused significant subjective discomfort and influenced quality of life...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27905359/-clinical-and-neuropsychological-features-of-alzheimer-s-disease-in-the-combination-with-cerebrovascular-disease
#10
N A Trusova, O S Levin, A V Arablinsky
AIM: To study clinical/neuropsychological and neuroimaging characteristics of Alzheimer's disease in the combination with cerebrovascular disease (CVD). MATERIAL AND METHODS: Ninety patients with dementia, including 35 patients with AD, 35 patients with mixed dementia (MD) and 20 patients with vascular dementia, were examined. The character of dementia was established according to NINCDS-ADRDA and NINDS-AIREN criteria. The neuropsychological battery included Addenbrooke's Cognitive Examination (ACE-R), Montreal Cognitive Assessment scale (MoCA), fluency test and the visual memory test (SCT)...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27903225/weight-bearing-joints-destruction-in-rheumatoid-arthritis
#11
Takashi Imagama, Atsunori Tokushige, Kazushige Seki, Toshihiko Taguchi
In many cases of rheumatoid arthritis (RA) joints of the upper extremities are affected. However, involvement of weight bearing joints of the lower extremities is strongly associated with a decreased activities of daily living ability such as gait disorder. Once the progression of weight bearing joint destruction occurs, lower extremity function will decrease even if RA disease activity is improved by pharmacotherapy. In this article, we investigated joint destruction-suppressing effects of pharmacotherapy on the hip and knee joints, as well as risk factors for joint destruction...
November 30, 2016: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/27900367/whole-genome-sequencing-of-two-probands-with-hereditary-spastic-paraplegia-reveals-novel-splice-donor-region-variant-and-known-pathogenic-variant-in-spg11
#12
Allen Chi-Shing Yu, Anne Yin-Yan Chan, Wing Chi Au, Yun Shen, Ting Fung Chan, Ho-Yin Edwin Chan
Hereditary spastic paraplegias (HSPs) are a group of heterogeneous neurodegenerative disorders, which are often presented with overlapping phenotypes such as progressive paraparesis and spasticity. To assist the diagnosis of HSP subtypes, next-generation sequencing is often used to provide supporting evidence. In this study, we report the case of two probands from the same family with HSP symptoms, including bilateral lower limb weakness, unsteady gait, cognitive decline, dysarthria, and slurring of speech since the age of 14...
November 2016: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/27879960/effectiveness-of-music-based-interventions-on-motricity-or-cognitive-functioning-in-neurological-populations-a-systematic-review
#13
Lousin Moumdjian, Teppo Sarkamo, Carmela Leone, Marc Leman, Peter Feys
INTRODUCTION: Motor and cognitive symptoms are frequent in persons with neurological disorders and often require extensive long-term rehabilitation. Recently, a variety of musicbased interventions have been introduced into neurological rehabilitation as training tools. AIM: This review aims to a) describe and define music-based intervention modalities and content which are applied in experimental studies, and b) describe the effects of these interventions on motor and/or cognitive symptoms in the neurological population...
November 23, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27878585/motion-and-emotion-anxiety-axial-connections-in-parkinson-s-disease
#14
Rastislav Šumec, Irena Rektorová, Robert Jech, Kateřina Menšíková, Jan Roth, Evžen Růžička, Dana Sochorová, Ladislav Dušek, Petr Kaňovský, Ivan Rektor, Tomáš Pavlík, Pavel Filip, Martin Bareš
Anxiety is a serious and frequent complication in Parkinson's disease (PD) that significantly affects the quality of life of patients. Multiple neuroanatomical, experimental, and clinical studies suggest its close association with axial disturbances. However, whether this relation applies for PD patients (commonly suffering from axial difficulties, such as balance and gait disturbance) has not been properly tested yet. The purpose of this study was to determine whether PD patients suffering from axial symptoms have higher levels of anxiety than others and to identify other factors associated with anxiety-axial connections...
November 23, 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27876119/primary-bladder-neck-obstruction-may-be-determined-by-postural-imbalances
#15
Tommaso Ciro Camerota, Matteo Zago, Stefano Pisu, Daniela Ciprandi, Chiarella Sforza
Primary bladder neck obstruction (PBNO) is a frequent under-investigated urological condition in which the bladder neck fails to open adequately during voiding. In the majority of cases no known etiological factor can be found. In this study we propose a new hypothesis to explain the origin of the disease in young male patients with no neurological disorders. We suggest a possible role of an unbalanced biomechanics of the pelvis on urethral sphincters activity and on functional bladder capacity. To support the proposed hypothesis, we present pilot gait analysis data of young male patients with primary bladder neck obstruction...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27876030/long-term-outcomes-following-lower-extremity-press-fit-bone-anchored-prosthesis-surgery-a-5-year-longitudinal-study-protocol
#16
Ruud A Leijendekkers, J Bart Staal, Gerben van Hinte, Jan Paul Frölke, Hendrik van de Meent, Femke Atsma, Maria W G Nijhuis-van der Sanden, Thomas J Hoogeboom
BACKGROUND: Patients with lower extremity amputation frequently suffer from socket-related problems. This seriously limits prosthesis use, level of activity and health-related quality of life (HRQoL). An additional problem in patients with lower extremity amputation are asymmetries in gait kinematics possibly accounting for back pain. Bone-anchored prostheses (BAPs) are a possible solution for socket-related problems. Knowledge concerning the level of function, activity and HRQoL after surgery is limited...
November 22, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27874167/-antibiotics-and-gait-disorders
#17
REVIEW
P Gomez-Porro, A Vinagre-Aragon, J A Zabala-Goiburu
The neurological toxicity of many antibiotics has been reported in a number of articles and clinical notes. In this review antibiotics are classified according to the physiopathogenic mechanism that can give rise to a gait disorder, taking both clinical and experimental data into account. An exhaustive search was conducted in Google Scholar and PubMed with the aim of finding reviews, articles and clinical cases dealing with gait disorders secondary to different antibiotics. The different antibiotics were separated according to the physiopathogenic mechanism that could cause them to trigger a gait disorder...
December 1, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27871435/resting-state-functional-connectivity-of-subthalamic-nucleus-in-different-parkinson-s-disease-phenotypes
#18
Zhan Wang, Huimin Chen, Huizi Ma, Lingyan Ma, Tao Wu, Tao Feng
Previous studies showed that the subthalamic nucleus (STN) plays a crucial role in Parkinson's disease (PD) pathophysiology. During rest, PD phenotypes exhibit different STN functional connectivity. STN functional connectivity was examined in 31 PD patients [12 tremor-dominant (TD) and 19 posture instability gait difficulty (PIGD)] and 22 healthy controls (HC). Compared with controls and PIGD patients, the TD patients exhibited higher functional connectivity between the bilateral STN and the left cerebellar anterior lobe...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27862267/spinal-cord-stimulation-improves-gait-in-patients-with-parkinson-s-disease-previously-treated-with-deep-brain-stimulation
#19
Carolina Pinto de Souza, Clement Hamani, Carolina Oliveira Souza, William Omar Lopez Contreras, Maria Gabriela Dos Santos Ghilardi, Rubens Gisbert Cury, Egberto Reis Barbosa, Manoel Jacobsen Teixeira, Erich Talamoni Fonoff
BACKGROUND: Deep brain stimulation and levodopatherapy ameliorate motor manifestations in Parkinson's disease, but their effects on axial signs are not sustained in the long term. OBJECTIVES: The objective of this study was to investigate the safety and efficacy of spinal cord stimulation on gait disturbance in advanced Parkinson's disease. METHODS: A total of 4 Parkinson's disease patients who experienced significant postural instability and gait disturbance years after chronic subthalamic stimulation were treated with spinal cord stimulation at 300 Hz...
November 10, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/27861371/chronic-lymphocytic-inflammation-with-pontine-perivascular-enhancement-responsive-to-steroids-clippers-with-intracranial-epstein-barr-virus-infection-a-case-report
#20
Yue Ma, Xiaolong Sun, Wen Li, Yi Li, Tao Kang, Xiai Yang, Wen Jiang
BACKGROUND: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder in the central nervous system (CNS) with distinct clinical, radiological, and pathological features. The pathophysiology of CLIPPERS still remains unclear and the reports are quite few. Although the radiological lesions were reported to be located predominantly in the pons, brachium pontis, and cerebellum, other adjacent structures such as the white matter and spinal cord were very recently reported as involved regions in CLIPPERS...
November 2016: Medicine (Baltimore)
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