keyword
https://read.qxmd.com/read/38269418/dexmedetomidine-and-magnesium-sulfate-in-preventing-junctional-ectopic-tachycardia-after-pediatric-cardiac-surgery
#1
JOURNAL ARTICLE
Passaint Fahim Hassan, Ahmed M El Haddad
BACKGROUND: Junctional ectopic tachycardia (JET) is a serious tachyarrhythmia following pediatric cardiac surgery. It isn't easy to treat and better to be prevented. This study aimed to examine the prophylactic effects of dexmedetomidine, MgSO4 , or their combination in reducing JET following pediatric open cardiac surgery. METHODS: Hundred and twenty children under 5 years, weighing more than 5 kg, who were scheduled for corrective acyanotic cardiac surgeries were randomized into three groups...
January 25, 2024: Paediatric Anaesthesia
https://read.qxmd.com/read/38213689/norepinephrine-boluses-for-the-prevention-of-post-reperfusion-syndrome-in-living-donor-liver-transplantation-a-prospective-open-label-single-arm-feasibility-trial
#2
JOURNAL ARTICLE
Moataz Maher Emara, Mahmoud Elsedeiq, Mostafa Abdelkhalek, Amr M Yassen, Mohamed A Elmorshedi
BACKGROUND AND AIMS: Post-reperfusion syndrome (PRS) is a serious haemodynamic event during liver transplantation (LT), which increases early graft dysfunction and mortality. This study aimed to test the efficacy and safety of norepinephrine (NE) boluses to prevent PRS during orthotopic LT. METHODS: This feasibility phase II trial prospectively recruited a single arm of 40 patients undergoing living donor LT. The intervention was an escalated protocol of NE boluses starting at 20 µg...
November 2023: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38173350/independent-sector-and-peri-operative-cardiac-arrest-as-reported-to-the-7th-national-audit-project-of-the-royal-college-of-anaesthetists
#3
JOURNAL ARTICLE
T M Cook, A D Kane, C Bouch, R A Armstrong, E Kursumovic, J Soar
The 7th National Audit Project (NAP7) of the Royal College of Anaesthetists studied peri-operative cardiac arrest including those that occurred in the independent healthcare sector, which provides around 1 in 6 NHS-funded care episodes. In total, 174 (39%) of 442 independent hospitals contacted agreed to participate. A survey examining provider preparedness for cardiac arrest had a response rate of 23 (13%), preventing useful analysis. An activity survey with 1912 responses (from a maximum of 45% of participating hospitals) showed that, compared with the NHS caseload, the independent sector caseload was less comorbid, with fewer patients at the extremes of age or who were severely obese, and with a large proportion of elective orthopaedic surgery undertaken during weekday working hours...
January 4, 2024: Anaesthesia
https://read.qxmd.com/read/38151793/successful-caudal-vena-cava-and-pulmonary-vein-isolation-in-healthy-horses-using-3d-electro-anatomical-mapping-and-a-contact-force-guided-ablation-system
#4
JOURNAL ARTICLE
Eva Buschmann, Glenn Van Steenkiste, Mattias Duytschaever, Tim Boussy, Ingrid Vernemmen, Lara Ibrahim, Stijn Schauvliege, Annelies Decloedt, Gunther van Loon
BACKGROUND: Recently, treatment of equine atrial tachycardia by three-dimensional electro-anatomical mapping (3D EAM) and radiofrequency catheter ablation (RFCA) has been described. Myocardial sleeves in the caudal vena cava and pulmonary veins are a potential trigger for initiation and perpetuation of atrial tachycardia and atrial fibrillation in the horse. Isolation of these myocardial sleeves by RFCA may be an effective treatment for these arrhythmias. OBJECTIVES: To describe the feasibility of 3D EAM and RFCA to isolate caudal vena cava and pulmonary veins in adult horses using 3D mapping and a contact force (CF)-guided ablation system...
December 27, 2023: Equine Veterinary Journal
https://read.qxmd.com/read/38118231/anaesthetic-management-of-paediatric-patients-undergoing-electrophysiology-study-and-ablation-for-supraventricular-tachycardia-a-focused-narrative-review
#5
REVIEW
Fabrizio Monaco, Jacopo D'Andria Ursoleo, Caterina Cecilia Lerose, Gaia Barucco, Margherita Licheri, Paolo Emilio Della Bella, Francesco Fioravanti, Simone Gulletta
Every year, 80,000-100,000 ablation procedures take place in the United States and approximately 1% of these involve paediatric patients. As the paediatric population undergoing catheter ablation to treat dysrhythmia is constantly growing, involvement of anaesthesiologists in the cardiac electrophysiology laboratory is simultaneously increasing. Compared with the adult population, paediatric patients need deeper sedation or general anaesthesia (GA) to guarantee motionlessness and preserve comfort. As a result, the anaesthesiologist working in this setting should keep in mind heart physiopathology as well as possible interactions between anaesthetic drugs and arrhythmia...
May 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38065830/pulsed-field-ablation-of-atrial-fibrillation-an-initial-australian-single-centre-experience
#6
JOURNAL ARTICLE
Xiang Wen Lee, Blake M Freeman, Nicole G Gunthorpe, Liam M Eagle, Meghan A Webster, John R Betts, Russell A Denman, Haris M Haqqani
BACKGROUND: Pulsed field ablation (PFA) is a newer ablation energy source with the potential to reduce complications and improve efficacy compared to conventional thermal atrial fibrillation (AF) ablation. This study aimed to present an initial single-centre Australian experience of PFA for AF ablation. METHODS: Initial consecutive patients undergoing PFA for paroxysmal or persistent AF at a single centre were included. Baseline patient characteristics, procedural data and clinical outcomes were collected prospectively at the time of the procedure...
December 7, 2023: Heart, Lung & Circulation
https://read.qxmd.com/read/38048986/risk-factors-for-poor-performance-in-finger-cuff-non-invasive-monitoring-of-arterial-pressure-a-prospective-multicenter-study
#7
JOURNAL ARTICLE
Karim Lakhal, Jérôme E Dauvergne, Hélène Messet-Charriere, Mai-Anh Nay, Toufik Kamel, Grégoire Muller, Vincent Robert-Edan, Bertrand Rozec, Stephan Ehrmann, Sophie Jacquier, Thierry Boulain
BACKGROUND: Compared to the invasive technique, non-invasive monitoring of arterial pressure favors easier and faster implementation while potentially sacrificing some reliability. This may be particularly true for the Clearsight™ system (Edwards Lifesciences), which enables continuous monitoring. We evaluated the risk factors for its poor performance. METHODS: Patients with an arterial catheter and stable mean arterial pressure (MAP) over a 5-min period were included...
December 2, 2023: Anaesthesia, Critical Care & Pain Medicine
https://read.qxmd.com/read/37944508/the-incidence-of-potentially-serious-complications-during-non-obstetric-anaesthetic-practice-in-the-united-kingdom-an-analysis-from-the-7th-national-audit-project-nap7-activity-survey
#8
JOURNAL ARTICLE
A D Kane, T M Cook, R A Armstrong, E Kursumovic, M T Davies, S Agarwal, J P Nolan, J H Smith, I K Moppett, F C Oglesby, L Cortes, C Taylor, J Cordingley, J Dorey, S J Finney, G Kunst, D N Lucas, G Nickols, R Mouton, B Patel, V J Pappachan, F Plaat, B R Scholefield, L Varney, J Soar
Complications and critical incidents arising during anaesthesia due to patient, surgical or anaesthetic factors, may cause harm themselves or progress to more severe events, including cardiac arrest or death. As part of the 7th National Audit Project of the Royal College of Anaesthetists, we studied a prospective national cohort of unselected patients. Anaesthetists recorded anonymous details of all cases undertaken over 4 days at their site through an online survey. Of 416 hospital sites invited to participate, 352 (85%) completed the survey...
January 2024: Anaesthesia
https://read.qxmd.com/read/37778938/intraoperative-blood-pressure-could-less-be-more
#9
EDITORIAL
Frederic Michard, Alexandre Joosten, Emmanuel Futier
Retrospective observational studies have reported a significant association between intraoperative hypotension and postoperative morbidity. However, association does not imply causation, and whether preventing intraoperative hypotension can improve patient outcome remains to be demonstrated. In this issue of the British Journal of Anaesthesia, D'Amico and colleagues meta-analysed 10 prospective randomised trials comparing low (≤60 mm Hg) and higher mean arterial pressure targets during anaesthesia and surgery...
November 2023: British Journal of Anaesthesia
https://read.qxmd.com/read/37775650/new-drug-discovery-of-cardiac-anti-arrhythmic-drugs-insights-in-animal-models
#10
JOURNAL ARTICLE
Ashish Kumar Sharma, Shivam Singh, Mehvish Bhat, Kartik Gill, Mohammad Zaid, Sachin Kumar, Anjali Shakya, Junaid Tantray, Divyamol Jose, Rashmi Gupta, Tsering Yangzom, Rajesh Kumar Sharma, Sanjay Kumar Sahu, Gulshan Rathore, Priyanka Chandolia, Mithilesh Singh, Anurag Mishra, Shobhit Raj, Archita Gupta, Mohit Agarwal, Sumaiya Kifayat, Anamika Gupta, Prashant Gupta, Ankit Vashist, Parth Vaibhav, Nancy Kathuria, Vipin Yadav, Ravindra Pal Singh, Arun Garg
Cardiac rhythm regulated by micro-macroscopic structures of heart. Pacemaker abnormalities or disruptions in electrical conduction, lead to arrhythmic disorders may be benign, typical, threatening, ultimately fatal, occurs in clinical practice, patients on digitalis, anaesthesia or acute myocardial infarction. Both traditional and genetic animal models are: In-vitro: Isolated ventricular Myocytes, Guinea pig papillary muscles, Patch-Clamp Experiments, Porcine Atrial Myocytes, Guinea pig ventricular myocytes, Guinea pig papillary muscle: action potential and refractory period, Langendorff technique, Arrhythmia by acetylcholine or potassium...
September 29, 2023: Scientific Reports
https://read.qxmd.com/read/37711929/analgesic-effects-of-magnesium-sulphate-as-an-adjuvant-to-fentanyl-for-monitored-anaesthesia-care-during-hysteroscopy
#11
JOURNAL ARTICLE
Sonal Mishra, Siddharth Jain, Shobha Purohit, Girdhari Lal, Neelu Sharma
BACKGROUND: Magnesium sulphate (MgSO4) is conventionally used in the treatment of eclampsia, refractive arrhythmias, asthma, etc. In our study, we aimed to study the analgesic effects of MgSO4 as an adjuvant to fentanyl and reduce the intraoperative opioid requirement to decrease their adverse effects. METHODS: A total of 122 patients scheduled for hysteroscopy were randomly divided into two groups. Patients in the magnesium group (group A) received intravenous MgSO4 50 mg/kg in 100 ml of isotonic saline over 15 minutes before anaesthesia induction and then 15 mg/kg per hour by continuous intravenous infusion...
August 2023: Curēus
https://read.qxmd.com/read/37654919/total-intravenous-anaesthesia-for-laparoscopic-cholecystectomy-in-a-patient-with-congenital-long-qt-syndrome-a-case-report
#12
Xinyan Zhang, Chun Lei Tan
Long QT syndrome (LQTS) is characterised by QT interval prolongation and ventricular arrhythmia, leading to sudden cardiac death. Patients with acquired or congenital LQTS pose special challenges to anaesthetists perioperatively due to the risk of developing life-threatening arrhythmia. A variety of medications, including commonly used volatile anaesthetic agents are known to prolong QT interval and there has been growing evidence of using total intravenous anaesthesia (TIVA) instead of volatile agents for such patients...
July 2023: Curēus
https://read.qxmd.com/read/37601502/anesthesiological-management-of-brugada-syndrome-patients-a-systematic-review
#13
REVIEW
Giuseppe Cuttone, Gennaro Martucci, Ruggero Napoli, Stefano Tigano, Antonio Arcadipane, Federico Pappalardo, Filippo Sanfilippo
Brugada syndrome (BrS) is a major risk factor for sudden cardiac death and ventricular tachyarrhythmias. Several drugs are contraindicated in patients with BrS, including some commonly administered drugs during anesthesia or in the perioperative period; however, there is still a paucity of evidence regarding BrS and common anesthetic pharmaceuticals. We conducted a systematic literature search (PubMed, updated October 10, 2022), including all studies reporting pharmacological management of BrS patients during anesthesia or intensive care, with a specific focus on proarrhythmic effects and possible pharmacological interactions in the context of BrS...
2023: Saudi Journal of Anaesthesia
https://read.qxmd.com/read/37542218/feasibility-and-safety-of-deep-sedation-with-propofol-and-remifentanil-in-spontaneous-breathing-during-endoscopic-retrograde-cholangiopancreatography-an-observational-prospective-study
#14
JOURNAL ARTICLE
Pasquale De Vico, Daniele G Biasucci, Lucia Aversano, Roberto Polidoro, Alessia Zingaro, Francesca Romana Millarelli, Giovanna Del Vecchio Blanco, Omero Alessandro Paoluzi, Edoardo Troncone, Giovanni Monteleone, Mario Dauri
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is an interventional procedure that requires deep sedation or general anaesthesia. The purpose of this prospective observational study was to assess the feasibility and safety of deep sedation in ERCP to maintain spontaneous breathing. METHODS: This is a single-centre observational prospective cohort study conducted in a tertiary referral university hospital. All consecutive patients who needed sedation or general anaesthesia for ERCP were included from January 2021 to June 2021...
August 4, 2023: BMC Anesthesiology
https://read.qxmd.com/read/37519545/comparative-evaluation-of-dexmedetomidine-and-magnesium-sulfate-for-prevention-of-postoperative-atrial-fibrillation-in-patients-of-coronary-artery-bypass-surgeries
#15
JOURNAL ARTICLE
Jui A Jadhav, Shrilekh Mankhair, Vivek Chakole
Introduction The main goal of this study is to compare the effects of dexmedetomidine and magnesium sulfate on preventing atrial fibrillation (AF) after off-pump coronary artery bypass graft (CABG) surgeries. AF is a type of irregular heartbeat that often occurs after heart surgery and can cause serious complications. We want to see which drug is more effective in reducing the risk of AF in patients who have had CABG surgeries without using a heart-lung machine.  Materials and methods This was a randomized clinical study, conducted on patients of ASA classes III and IV who were the candidates for off-pump coronary artery bypass graft surgeries, which were conducted in the cardiac operating room from the period October 2020 to April 2021, at the Department of Anaesthesia, Jawaharlal Nehru Medical College, Sawangi, Meghe...
June 2023: Curēus
https://read.qxmd.com/read/37470523/effect-of-preoperative-ivabradine-on-hemodynamics-during-elective-off-pump-cabg
#16
RANDOMIZED CONTROLLED TRIAL
Sanjula Virmani, Indira Mallik, Vishwanath B Mohire, Muhammad Abid Geelani, Harpreet Singh Minhas
BACKGROUND: Ivabradine is a specific heart rate (HR)-lowering agent which blocks the cardiac pacemaker If channels. It reduces the HR without causing a negative inotropic or lusitropic effect, thus preserving ventricular contractility. The authors hypothesized that its usefulness in lowering HR can be utilized in patients undergoing off-pump coronary artery bypass (OPCAB) surgery. OBJECTIVE: To study the effects of preoperative ivabradine on hemodynamics (during surgery) in patients undergoing elective OPCAB surgery...
2023: Annals of Cardiac Anaesthesia
https://read.qxmd.com/read/37456460/propofol-in-icu-settings-understanding-and-managing-anti-arrhythmic-pro-arrhythmic-effects-and-propofol-infusion-syndrome
#17
REVIEW
Jananthan Paramsothy, Sai Dheeraj Gutlapalli, Vijay Durga Pradeep Ganipineni, Isabelle Mulango, Ikpechukwu J Okorie, Divine Besong Arrey Agbor, Crystal Delp, Hanim Apple, Borislav Kheyson, Jay Nfonoyim, Nidal Isber, Mallikarjuna Yalamanchili
Propofol has revolutionized anesthesia and intensive care medicine owing to its favorable pharmacokinetic characteristics, fast onset, and short duration of action. This drug has been shown to be remarkably effective in numerous clinical scenarios. In addition, propofol has maintained an overwhelmingly favorable safety profile; however, it has been associated with both antiarrhythmic and proarrhythmic effects. This review concisely summarizes the dual arrhythmic cardiovascular effects of propofol and a rare but serious complication, propofol infusion syndrome (PRIS)...
June 2023: Curēus
https://read.qxmd.com/read/37430181/effects-of-remimazolam-on-hemodynamic-changes-during-cardiac-ablation-for-atrial-fibrillation-under-general-anesthesia-a-propensity-score-matched-retrospective-cohort-study
#18
REVIEW
Sun Woo Nam, Subin Yim, Chang Ik Choi, Insun Park, Kyoung-Woon Joung, In-Ae Song
PURPOSE: Abrupt hemodynamic changes or life-threatening arrhythmias are frequently observed in individuals receiving anesthesia for cardiac arrhythmia ablation. Remimazolam is a novel ultra-short-acting benzodiazepine that has been associated with better hemodynamic stability than conventional anesthetic agents do. This study aimed to investigate whether remimazolam reduces vasoactive agent use compared with desflurane in individuals undergoing ablation for atrial fibrillation under general anesthesia...
September 2023: Canadian Journal of Anaesthesia
https://read.qxmd.com/read/37426055/reverse-takotsubo-cardiomyopathy-induced-by-adrenaline-containing-irrigation-solution-during-shoulder-arthroscopy
#19
K Azem, O Kaplan, B Zribi, J Elliston, E Mangoubi, K Orvin, S Fein
Takotsubo cardiomyopathy is characterised by reversible systolic dysfunction resulting from catecholamine-induced vasospasm, mainly triggered by intense emotional or physical stress. Adding adrenaline to arthroscopic irrigation solution enhances visibility by minimising bleeding. However, there is a risk of complications due to systemic absorption. Several severe cardiac consequences have been described. Here, we present a case of a patient who underwent elective shoulder arthroscopy involving an adrenaline-containing irrigation solution...
2023: Anaesthesia reports
https://read.qxmd.com/read/37302956/prophylactic-use-of-a-lidocaine-constant-rate-infusion-versus-saline-in-dogs-undergoing-balloon-valvuloplasty-for-management-of-pulmonic-stenosis-a-randomized-control-trial
#20
JOURNAL ARTICLE
Victoria Phillips, Chris Linney, Brigite Pedro, Joao Neves, Antonia Mavropoulou, Fabio Sarcinella, Simon Swift, Tim Sparks, Alessandra Mathis
OBJECTIVE: To evaluate the effect of a prophylactic lidocaine constant rate infusion (CRI) on the incidence and malignancy of catheter-induced ventricular ectopic complexes (VECs) during balloon valvuloplasty for management of pulmonic stenosis in dogs. STUDY DESIGN: Single-centre, prospective, randomized study. ANIMALS: Client-owned dogs (n = 70) with pulmonic stenosis. METHODS: Dogs were randomly assigned to one of two anaesthetic protocols: administration of lidocaine 2 mg kg-1 bolus followed by a CRI (50 μg kg-1 minute-1 ; group LD) or a saline placebo (group SL) during balloon valvuloplasty...
September 2023: Veterinary Anaesthesia and Analgesia
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