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https://www.readbyqxmd.com/read/29332249/correlation-of-flow-density-as-measured-using-optical-coherence-tomography-angiography-with-structural-and-functional-parameters-in-glaucoma-patients
#1
Maged Alnawaiseh, Larissa Lahme, Viktoria Müller, André Rosentreter, Nicole Eter
PURPOSE: To evaluate the correlation between flow density, as measured by optical coherence tomography angiography (OCTA), and structural and functional parameters in patients with open-angle glaucoma. METHODS: Thirty-four eyes of 34 patients with open-angle glaucoma and 35 eyes of 35 healthy subjects were prospectively included in this study. OCTA was performed using RTVue XR Avanti with AngioVue. The macula was imaged with a 3 × 3 mm scan and the optic nerve head (ONH) with a 4...
January 13, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29332093/structure-function-correlation-in-hemianopic-vision-loss-in-children-aged-3-6-years-using-oct-and-svop-and-comparison-with-adult-eyes
#2
Wadim Bowl, Robert Knobloch, Silke Schweinfurth, Kerstin Holve, Knut Stieger, Birgit Lorenz
PURPOSE: To correlate visual field assessment with saccadic vector optokinetic perimetry (SVOP) in children with ganglion cell loss due to anterior pathway pathologies resulting in hemianopic visual field defects measured with optical coherence tomography (OCT). METHODS: 5 young (aged 3-6 years) and 5 adult patients with hemianopia, 10 healthy preschoolers (mean age 4.4 years), and 10 healthy adults (mean age 25.3 years) were tested with SVOP and OCT (focusing on the ganglion cell layer, GCL+)...
January 13, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29330448/visual-field-loss-and-vision-related-quality-of-life-in-the-italian-primary-open-angle-glaucoma-study
#3
Eliana Rulli, Luciano Quaranta, Ivano Riva, Davide Poli, Lital Hollander, Fabio Galli, Andreas Katsanos, Francesco Oddone, Valter Torri, Robert N Weinreb
The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality of life (QoL) and glaucoma-related symptoms in a large cohort of primary open angle glaucoma (POAG) patients. POAG patients with or without VF defects or "glaucoma suspect" patients were considered eligible. QoL was assessed using the validated versions of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and glaucoma-related symptoms were assessed using the Glaucoma Symptom Scale (GSS)...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329947/-pseudoexfoliation-syndrome-and-pseudoexfoliation-glaucoma
#4
REVIEW
C Schweitzer
Pseudoexfoliation syndrome is an age-related systemic disease that mainly affects the anterior structures of the eye. Despite a worldwide distribution, reported incidence and prevalence of this syndrome vary widely between ethnicities and geographical areas. The exfoliative material is composed mainly of abnormal cross-linked fibrils that accumulate progressively in some organs such as the heart, blood vessels, lungs or meninges, and particularly in the anterior structures of the eye. The exact pathophysiological process still remains unclear but the association of genetic and environmental factors are thought to play a role in the development and progressive extracellular accumulation of exfoliative material...
January 9, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29329138/relationship-of-macular-thickness-and-function-to-optical-microangiography-measurements-in-glaucoma
#5
Harsha L Rao, Mohammed Riyazuddin, Srilakshmi Dasari, Narendra K Puttaiah, Zia S Pradhan, Robert N Weinreb, Kaweh Mansouri, Carroll A B Webers
PURPOSE: To evaluate the relationship between macular optical microangiography (OMAG), ganglion cell-inner plexiform layer (GCIPL) thickness and visual sensitivity measurements of different macular sectors in primary open angle glaucoma (POAG). METHODS: In a cross-sectional study, 39 eyes of 26 POAG patients underwent OCT imaging and 10-2 visual field examination of the macula in the same session. Linear regression models were used to evaluate the relationships between OMAG, GCIPL thickness and visual sensitivity measurements in different macular sectors...
January 11, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29328170/highly-directive-plasmonic-structure-with-double-resonance-at-excitation-and-emission-for-molecule-enhanced-fluorescence
#6
Fangzhou Wang, Guoguo Kang
An improved bull's eye nanostructure is proposed as a substrate for surface-enhanced fluorescence. Optimized by finite-difference time-domain, annular corrugation on both upper and lower surfaces is placed around a nanobow tie in the middle. The whole structure is designed for the excitation and emission process of a certain fluorescence simultaneously, which can enhance the fluorescence intensity enormously (35 times for an excitation field and 120 times for radiation, independently). Meanwhile, it is able to confine the far-field emission energy within a divergence angle of ±3...
January 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29327365/millimeter-spatial-resolution-in-vivo-sodium-mri-of-the-human-eye-at-7-t-using-a-dedicated-radiofrequency-transceiver-array
#7
Daniel Wenz, Andre Kuehne, Till Huelnhagen, Armin M Nagel, Helmar Waiczies, Oliver Weinberger, Celal Oezerdem, Oliver Stachs, Soenke Langner, Erdmann Seeliger, Bert Flemming, Russell Hodge, Thoralf Niendorf
PURPOSE: The aim of this study was to achieve millimeter spatial resolution sodium in vivo MRI of the human eye at 7 T using a dedicated six-channel transceiver array. We present a detailed description of the radiofrequency coil design, along with electromagnetic field and specific absorption ratio simulations, data validation, and in vivo application. METHODS: Electromagnetic field and specific absorption ratio simulations were performed. Transmit field uniformity was optimized by using a multi-objective genetic algorithm...
January 12, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29325962/systematic-review-of-factors-influencing-surgical-performance-practical-recommendations-for-microsurgical-procedures-in-neurosurgery
#8
Evgenii Belykh, Naomi R Onaka, Iraklii T Abramov, Kaan Yağmurlu, Vadim A Byvaltsev, Robert F Spetzler, Peter Nakaji, Mark C Preul
BACKGROUND: Microneurosurgical techniques involve complex manual skills and hand-eye coordination that require substantial training. Many factors affect microneurosurgical skills. The goal of this study was to use a systematic evidence-based approach to analyze the quality of evidence for intrinsic and extrinsic factors that influence microneurosurgical performance and to make weighted practical recommendations. MATERIALS AND METHODS: A literature search of factors that may impact microsurgical performance was conducted using PubMed and Embase...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29323932/the-effects-of-breath-alcohol-concentration-on-postural-control
#9
Dary D Fiorentino
STRUCTURED ABSTRACT Background: Two of the three standardized field sobriety tests that US law enforcement uses at roadside checks have a postural equilibrium component to them. Those tests have been validated to detect impairment caused by blood alcohol concentrations (BACs) of .08 g/dL or above. Many medical and traffic safety associations support a lower limit, and one state, Utah, has passed a law to lower the limit to .05 g/dL. Many studies have examined the effects of alcohol on postural control (of which postural equilibrium is a component), with a consensus emerging that impairment is usually found at BACs greater than ...
January 11, 2018: Traffic Injury Prevention
https://www.readbyqxmd.com/read/29321667/the-management-of-retinoblastoma
#10
REVIEW
Ido D Fabian, Zerrin Onadim, Esin Karaa, Catriona Duncan, Tanzina Chowdhury, Irene Scheimberg, Shin-Ichi Ohnuma, M Ashwin Reddy, Mandeep S Sagoo
Retinoblastoma (Rb) is the most common primary intraocular malignancy of childhood, but an uncommon paediatric cancer, with a constant incidence worldwide of 1:15,000-1:20,000 live births. Despite its rarity, Rb has served as a cornerstone in the field of oncology in many of the aspects that comprise cancer management, including classification schemes, treatment modalities, genetic testing and screening. Until just over half a century ago, the major treatment for Rb was eye removal, and prognosis was poor with outcome fatal for most children...
January 11, 2018: Oncogene
https://www.readbyqxmd.com/read/29320503/pattern-of-peripapillary-capillary-density-loss-in-ischemic-optic-neuropathy-compared-to-that-in-primary-open-angle-glaucoma
#11
Masoud Aghsaei Fard, Yanin Suwan, Sasan Moghimi, Lawrence S Geyman, Toco Y Chui, Richard B Rosen, Robert Ritch
PURPOSE: Both non-arteritic anterior ischemic optic neuropathy (NAION) and primary open-angle glaucoma (POAG) damage retinal ganglion cell axons, which are perfused by the radial peripapillary capillaries. To evaluate the pattern of ischemia, we compared peripapillary capillary density (PCD) in NAION eyes to POAG eyes matched for visual field mean deviation and retinal nerve fiber layer thickness. METHODS: 31 chronic NAION (>6 months after the acute event) and unaffected fellow eyes (31 subjects), 42 moderate and severe POAG eyes (27 subjects), and 77 control eyes (46 healthy subjects) were imaged with a commercial optical coherence tomography angiography system (AngioVue, Avanti RTVue-XR, Optovue, CA) at two academic institutions...
2018: PloS One
https://www.readbyqxmd.com/read/29319875/association-between-sensory-impairment-and-dementia-in-older-adults-evidence-from-china
#12
Yanan Luo, Ping He, Chao Guo, Gong Chen, Ning Li, Xiaoying Zheng
OBJECTIVES: To determine the association between sensory impairment and dementia in Chinese older adults. DESIGN: Cross-sectional. SETTING: Older adults in 31 provinces of China. PARTICIPANTS: Individuals aged 65 and older (N = 250,752). MEASUREMENTS: Psychiatrists ascertained dementia based on the International Classification of Diseases, 10th Revision. Sensory impairment was measured as only hearing impairment, only vision impairment, and combined sensory impairment (combined hearing and vision impairment)...
January 10, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29318883/colorimetric-and-electrochemiluminecence-dual-mode-sensing-of-lead-ion-based-on-integrated-lab-on-paper-device
#13
Jinmeng Xu, Yan Zhang, Li Li, Qingkun Kong, Lina Zhang, Shenguang Ge, Jinghua Yu
A highly selective two-point separation strategy was designed based on a cross-like all-in-one lab-on-paper analytical device. The stable and cleavable enzyme-coated reduced graphene oxide (rGO)-PdAu probe was fabricated as the signal reporter to enable visualization and electrochemiluminecence (ECL) dual mode sensing of Pb2+. Concretely, the experimental workflow consists of the following process, (i) fabrication of the lab-on-paper device and growth of Au NPs on ECL detection zone, (ii) immobilization of Pb2+-specific DNAzyme, (iii) hybridization between DNAzyme and rGO-PdAu-glucose oxidase (GOx) labeled oligonucleotide to form double-stranded DNA...
January 10, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29317758/speech-prosodies-of-different-emotional-categories-activate-different-brain-regions-in-adult-cortex-an-fnirs-study
#14
Dandan Zhang, Yu Zhou, Jiajin Yuan
Emotional expressions of others embedded in speech prosodies are important for social interactions. This study used functional near-infrared spectroscopy to investigate how speech prosodies of different emotional categories are processed in the cortex. The results demonstrated several cerebral areas critical for emotional prosody processing. We confirmed that the superior temporal cortex, especially the right middle and posterior parts of superior temporal gyrus (BA 22/42), primarily works to discriminate between emotional and neutral prosodies...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29317634/punctuated-evolution-of-canonical-genomic-aberrations-in-uveal-melanoma
#15
Matthew G Field, Michael A Durante, Hima Anbunathan, Louis Z Cai, Christina L Decatur, Anne M Bowcock, Stefan Kurtenbach, J William Harbour
Cancer is thought to arise through the accumulation of genomic aberrations evolving under Darwinian selection. However, it remains unclear when the aberrations associated with metastasis emerge during tumor evolution. Uveal melanoma (UM) is the most common primary eye cancer and frequently leads to metastatic death, which is strongly linked to BAP1 mutations. Accordingly, UM is ideally suited for studying the clonal evolution of metastatic competence. Here we analyze sequencing data from 151 primary UM samples using a customized bioinformatic pipeline, to improve detection of BAP1 mutations and infer the clonal relationships among genomic aberrations...
January 9, 2018: Nature Communications
https://www.readbyqxmd.com/read/29317211/baseline-24-2-central-visual-field-damage-is-predictive-of-global-progressive-field-loss
#16
Aakriti Garg, C Gustavo De Moraes, George A Cioffi, Christopher A Girkin, Felipe A Medeiros, Robert N Weinreb, Linda Zangwill, Jeffrey M Liebmann
PURPOSE: Central visual field (VF) damage in glaucoma patients can significantly hinder daily activities. The present study investigates whether the presence of localized baseline damage to the central ten degrees of the VF is predictive of faster global mean deviation (MD) progression. DESIGN: Prospective, cohort study. METHODS: Eyes from the multicenter African Descent and Glaucoma Evaluation Study (ADAGES) with established glaucoma and VF loss and a minimum of five 24-2 VFs were eligible...
January 6, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29315718/experimental-investigation-of-accommodation-in-eyes-fit-with-multifocal-contact-lenses-using-a-clinical-auto-refractor
#17
Basal H Altoaimi, Pete Kollbaum, Dawn Meyer, Arthur Bradley
PURPOSE: Multifocal or multi-zone contact lenses are increasingly being fit to young eyes in an attempt to control myopia progression. However, success in achieving this aim may depend on how much the eye accommodates. The purpose of the current work was to evaluate the ability of an open-field clinical autorefractor to measure on-axis refractive state and accommodation in eyes fit with multifocal contact lenses (CLs). METHODS: Refractive state was measured with a Grand Seiko WAM-5500 autorefractor (www...
January 8, 2018: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29313524/multichannel-spectrometers-in-animals
#18
Thomas Wells Cronin, Missael Garcia, Viktor Gruev
Multispectral, hyperspectral, polarimetric, and other types of multichannel imaging spectrometers are coming into common use for a variety of applications, including remote sensing, material identification, forensics, and medical diagnosis. These instruments are often bulky and intolerant of field abuse, so designing compact, reliable, portable, and robust devices is a priority. In contrast to most engineering designs, animals have been building compact and robust multichannel imaging systems for millennia - their eyes...
January 9, 2018: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/29313398/a-15-year-review-of-secondary-and-tertiary-optic-nerve-sheath-fenestration-for-idiopathic-intracranial-hypertension
#19
Andrew J Anzeljc, Patrick Frias, Brent R Hayek, Nancy Canter Weiner, Ted H Wojno, H Joon Kim
PURPOSE: Optic nerve sheath fenestration (ONSF) is a common surgical option for patients with idiopathic intracranial hypertension (IIH) with vision loss refractory to medical management. Little is known about the visual benefit of repeated ONSF. The authors aimed to assess the efficacy of secondary and tertiary ONSF in patients with IIH. METHODS: A retrospective chart review was performed on all patients with repeat ONSF for IIH at Emory University from 1999 to 2016...
January 9, 2018: Orbit
https://www.readbyqxmd.com/read/29312847/augmented-reality-the-use-of-the-picolinker-smart-glasses-improves-wire-insertion-under-fluoroscopy
#20
Takafumi Hiranaka, Takaaki Fujishiro, Yuichi Hida, Yosaku Shibata, Masanori Tsubosaka, Yuta Nakanishi, Kenjiro Okimura, Harunobu Uemoto
AIM: To demonstrate the feasibility of the wearable smart glasses, PicoLinker, in guide wire insertion under fluoroscopic guidance. METHODS: Under a fluoroscope, a surgeon inserted 3 mm guide wires into plastic femurs from the lateral cortex to the femoral head center while the surgeon did or did not wear PicoLinker, which are wearable smart glasses where the fluoroscopic video was displayed (10 guide wires each). RESULTS: The tip apex distance, radiation exposure time and total insertion time were significantly shorter while wearing the PicoLinker smart glasses...
December 18, 2017: World Journal of Orthopedics
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