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https://www.readbyqxmd.com/read/29790923/missed-opportunities-to-prescribe-preexposure-prophylaxis-in-south-carolina-2013-2016
#1
Dawn K Smith, Man-Huei Chang, Wayne A Duffus, Stella Okoye, Sharon Weissman
Introduction: Expanding use of preexposure prophylaxis (PrEP) in ways that address current racial/ethnic disparities is an important HIV prevention goal. We investigated missed opportunities to provide PrEP during healthcare visits occurring prior to HIV infection. Methods: This retrospective cohort study linked South Carolina HIV case surveillance data to 3 statewide healthcare databases. Characteristics of patients, health care visits and providers, sexually transmitted diseases (STD), and other diagnoses, were assessed for medical encounters occurring before an initial HIV diagnosis...
May 22, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29782302/reasons-for-not-using-condoms-among-heterosexual-men-in-belgrade-serbia
#2
Milan Bjekić, Sandra Sipetić-Grujičić, Hristina Vlajinac, Aleksandra Nikolić
Dear Editor, Proper and consistent use of male condoms can be a highly effective method of preventing the transmission of sexually transmitted infections (STIs) and HIV (1), but this method relies on men's willingness and ability to use condoms. In the United States of America, about 20% overall and less than 50% of adults with multiple partners used a condom at last intercourse (2). In Serbia in 2013 (3), 50.0% of women and 62.5% of men aged 15-49 who had more than one partner in the past year used a condom during their last intercourse...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29779985/systems-biology-based-investigation-of-host-plasmodium-interactions
#3
REVIEW
Maren L Smith, Mark P Styczynski
Malaria is a serious, complex disease caused by parasites of the genus Plasmodium. Plasmodium parasites affect multiple tissues as they evade immune responses, replicate, sexually reproduce, and transmit between vertebrate and invertebrate hosts. The explosion of omics technologies has enabled large-scale collection of Plasmodium infection data, revealing systems-scale patterns, mechanisms of pathogenesis, and the ways that host and pathogen affect each other. Here, we provide an overview of recent efforts using systems biology approaches to study host-Plasmodium interactions and the biological themes that have emerged from these efforts...
May 18, 2018: Trends in Parasitology
https://www.readbyqxmd.com/read/29779827/zika-virus-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#4
Gisele Sampaio Silva, Guy A Richards, Tim Baker, Jorge Hidalgo, Juan Ignacio Silesky Jiménez, Pravin Amin
Zika fever is an acute infectious disease caused by the Zika virus (ZIKV), an RNA virus belonging to the genus Flavivirus. ZIKV can be transmitted by bites from Aedes aegypti and Aedes albopictus species, sexual activity, blood transfusion and from mother to fetus during pregnancy and delivery. A total of 50 territories and countries in the Americas had reported ZIKV infections. For those with symptoms, the presentation is similar to dengue fever with body aches, joint pain, fatigue, malaise, fever and conjunctivitis lasting up to seven days...
April 5, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29776807/public-health-surveillance-of-multidrug-resistant-clones-of-neisseria-gonorrhoeae-in-europe-a-genomic-survey
#5
Simon R Harris, Michelle J Cole, Gianfranco Spiteri, Leonor Sánchez-Busó, Daniel Golparian, Susanne Jacobsson, Richard Goater, Khalil Abudahab, Corin A Yeats, Beatrice Bercot, Maria José Borrego, Brendan Crowley, Paola Stefanelli, Francesco Tripodo, Raquel Abad, David M Aanensen, Magnus Unemo
BACKGROUND: Traditional methods for molecular epidemiology of Neisseria gonorrhoeae are suboptimal. Whole-genome sequencing (WGS) offers ideal resolution to describe population dynamics and to predict and infer transmission of antimicrobial resistance, and can enhance infection control through linkage with epidemiological data. We used WGS, in conjunction with linked epidemiological and phenotypic data, to describe the gonococcal population in 20 European countries. We aimed to detail changes in phenotypic antimicrobial resistance levels (and the reasons for these changes) and strain distribution (with a focus on antimicrobial resistance strains in risk groups), and to predict antimicrobial resistance from WGS data...
May 15, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29776778/three-years-post-affordable-care-act-sexually-transmitted-disease-clinics-remain-critical-among-vulnerable-populations
#6
Nicky J Mehtani, Christina M Schumacher, Luke E Johnsen, Adena Greenbaum, C Patrick Chaulk, Khalil G Ghanem, Jacky M Jennings, Kathleen R Page
INTRODUCTION: The purpose of the study is to examine whether demand for publicly funded sexually transmitted disease clinics changed after Affordable Care Act implementation. METHODS: The percentages of total incident sexually transmitted infections in Baltimore City that occurred at publicly funded sexually transmitted disease clinics were compared between the 3 years prior to and following the 2014 Medicaid and private insurance expansions. Risk factors associated with diagnosis at sexually transmitted disease clinics were identified using log binomial regression...
May 15, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29771869/performance-of-the-atlas-rapid-test-for-chlamydia-trachomatis-and-women-s-attitudes-toward-point-of-care-testing
#7
Lea E Widdice, Yu-Hsiang Hsieh, Barbara Silver, Mathilda Barnes, Perry Barnes, Charlotte A Gaydos
PURPOSE: This study compared performance of Atlas io® diagnostic platform, a point-of-care (POC) PCR assay for Chlamydia trachomatis (CT), to Aptima Combo 2, a standard of care laboratory-based nucleic acid amplification assay (NAAT), and evaluated patient attitudes toward POC testing. METHODS: Women ≥14 years undergoing CT screening/testing were recruited from an urban adolescent primary care practice (Teen Health Center, THC) and a sexually transmitted disease (STD) clinic...
May 1, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29771866/bipolar-disorder-is-associated-with-an-increased-risk-of-sexually-transmitted-infections-a-nationwide-population-based-cohort-study
#8
Shih-Fen Chen, Ling-Yi Wang, Jen-Huai Chiang, Yu-Chih Shen
BACKGROUND: Previous studies have suggested that sexually transmitted infections (STI) tend to increase in patients with bipolar disorder during a manic or hypomanic episode. However, in the long-term course of this disease, it is unclear whether patients with bipolar disorder have a higher risk of incident STI. METHODS: Using the National Health Insurance Research Database (NHIRD) of Taiwan, 3,721 patients with bipolar disorder and 14,884 controls without bipolar disorder matched by gender and age were enrolled between 2000 and 2010 and followed until the end of 2013...
May 1, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29770100/lymphogranuloma-venereum-in-quebec-re-emergence-among-men-who-have-sex-with-men
#9
C A Boutin, S Venne, M Fiset, C Fortin, D Murphy, A Severini, C Martineau, J Longtin, A C Labbé
Background: Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis genotypes L1 , L2 and L3 . This LGV is associated with significant morbidity and increased risk of HIV transmission. While fewer than two cases per year were reported in Quebec before 2005, LGV emerged in 2005-2006 with 69 cases, followed by a period of low incidence (2007-2012), and subsequent re-emergence since 2013. Objectives: To describe the incidence of LGV in Quebec and the characteristics of the affected population, including demographics and risk factors, clinical manifestations, laboratory tests, treatments and reinfection rates...
February 1, 2018: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29770078/evaluating-the-timeliness-of-reporting-in-a-first-nations-communicable-diseases-program
#10
A Lam, S Woods, N Ndubuka
Background: Timely reporting of communicable diseases is necessary to enable a prompt response to mitigate and control outbreaks. This is especially true among First Nations communities due to a number of factors, including unique social determinants of health, which can contribute to rapid disease transmission. Objective: To assess the timeliness of reporting for 12 notifiable communicable diseases in the Northern Inter-Tribal Health Authority, which includes 33 First Nations on-reserve communities in Northern Saskatchewan, Canada, and to assess whether there were differences in reporting times depending on degree of remoteness of community, season or year...
June 1, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29769280/molecular-diagnosis-of-bacterial-vaginosis-an-update
#11
Jenell S Coleman, Charlotte A Gaydos
Bacterial vaginosis (BV) is the most common cause of vaginal discharge in reproductive age women. BV has been associated with poor reproductive outcomes like preterm delivery, acquisition of sexually transmitted infections including HIV, and pelvic inflammatory disease. BV represents acquisition of a diverse community of anaerobic and facultative bacteria and a reduction in lactobacilli. It can be diagnosed using several tests ranging from clinical indicators, point-of-care tests, and molecular assays. Molecular technologies are objective, able to detect fastidious bacteria, allow quantitation, and are ideal for self-collected vaginal swabs...
May 16, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29768621/sexual-violence-against-women-and-care-in-the-health-sector-in-santa-catarina-brazil
#12
Carmem Regina Delziovo, Elza Berger Salema Coelho, Eleonora d'Orsi, Sheila Rubia Lindner
This is a study on sexual violence against women in the Brazilian State of Santa Catarina notified to the Notifiable Diseases Information System (SINAN) in the period 20082013. It aimed to estimate pregnancy and sexually transmitted infections (STIs) resulting from sexual violence and to test the association between pregnancy, STIs and care provided in health services. In total, 1,230 pregnancy notifications and 1.316 STI notifications were analyzed. Variables were age, schooling, time to receive care, STI prophylaxis, emergency contraception, number of perpetrators and recurrent violence, which were analyzed using proportions and 95% confidence intervals...
May 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29768419/a-secreted-heat-shock-protein-90-of-trichomonas-vaginalis
#13
Meetali Singh, Divya Beri, Rishi Kumar Nageshan, Leena Chavaan, Darshak Gadara, Mukta Poojary, Suraj Subramaniam, Utpal Tatu
Trichomonas vaginalis is a causative agent of Trichomoniasis, a leading non-viral sexually transmitted disease worldwide. In the current study, we show Heat shock protein 90 is essential for its growth. Upon genomics analysis of the parasite, it was found to possess seven ORFs which could potentially encode Hsp90 isoforms. We identified a cytosolic Hsp90 homolog, four homologs which can align to truncated cytosolic Hsp90 gene products along with two Grp94 homologs (ER isoform of Hsp90). However, both Grp94 orthologs lacked an ER retention motif...
May 16, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29765926/sexual-disharmony-in-menopausal-women-and-their-husband-a-qualitative-study-of-reasons-strategies-and-ramifications
#14
Masumeh Ghazanfarpour, Talat Khadivzadeh, Robab Latifnejad Roudsari
Objectives: The goal of this study was to explore perceptions and experiences of general practitioners and midwives during sexual dialogue with menopausal women. Methods: In a descriptive exploratory qualitative study, 13 midwives and 12 general practitioners were selected using a semi-structured interview and purposive sampling method. Data analysis was conducted using qualitative content analysis adopted by Graneheim and Lundman. Results: Through data analysis "sexual disharmony" emerged as a central theme, which included three categories of reasons, strategies, and ramifications of sexual disharmony...
April 2018: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29765114/evaluation-of-the-utility-of-a-rapid-test-for-syphilis-at-a-sexually-transmitted-disease-clinic-in-buenos-aires-argentina
#15
Lucía Gallo Vaulet, Nicolás Morando, Ricardo Casco, Asunta Melgar, Silvia Nacher, Marcelo Rodríguez Fermepin, María A Pando
Even though syphilis can be easily diagnosed by simple and low-cost laboratory methods, it continues to be an important health problem. Rapid tests (RT) for the detection of treponemal antibodies can facilitate earlier diagnosis, access to treatment and linkage to care. The aim of this study was to analyse the usefulness of the incorporation of a RT in the detection of patients infected with T. pallidum in a sexually-transmitted disease (STD) clinic. Between March and December 2015, a syphilis RT was offered to patients who spontaneously attended the clinic...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29764311/changes-in-the-swinging-lifestyle-a-us-national-and-historical-comparison
#16
Claire Kimberly, Robert McGinley
Although engaging in extramarital relationships with permission from spouses has been practised for generations, relatively little is known about those who participate and how they have changed over the years. This study expands on existing research by comparing the demographics and sexual practices of those in swinging and non-swinging communities from the 1980s to those in 2016. Data from the 1980s were collected through membership forms submitted to a swinger organisation and a national dataset conducted in the USA (i...
May 15, 2018: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/29755057/processes-and-outcomes-of-a-community-based-participatory-research-driven-health-needs-assessment-a-tool-for-moving-health-disparity-reporting-to-evidence-based-action
#17
Tabia Henry Akintobi, Elise Lockamy, Lisa Goodin, Natalie D Hernandez, Tanesha Slocumb, Daniel Blumenthal, Ronald Braithwaite, Larry Leeks, Micah Rowland, Thomas Cotton, LaShawn Hoffman
BACKGROUND: The community-based participatory research (CBPR)-driven health needs assessment was a tool used to inform community-led, -implemented, and -sustained research and prevention strategies. METHODS: The Morehouse School of Medicine Prevention Research Center (MSM PRC) research and prevention initiatives are implemented in direct response to priorities identified through this process and tool. Led by a community-majority coalition board, the assessment coupled state and city secondary data with primary survey data collected by and from community residents...
2018: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29750775/assessing-sexually-transmitted-disease-partner-services-in-state-and-local-health-departments
#18
Kendra M Cuffe, Jami S Leichliter, Thomas L Gift
State and local health department sexually transmitted disease (STD) programs provide several partner services to reduce disease transmission. Budget cuts and temporary staff reassignments for public health emergencies may affect the provision of partner services. Determining the impact of staffing reductions on STD rates and public health response should be further assessed.
June 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29750774/genital-wart-and-human-papillomavirus-prevalence-in-men-in-the-united-states-from-penile-swabs-results-from-national-health-and-nutrition-examination-surveys
#19
Michael Daugherty, Timothy Byler
INTRODUCTION: Human papillomavirus (HPV) is a common sexually transmitted infection in the United States that can lead to both malignant (high-risk) and benign (low-risk) findings. These low-risk findings include both genital condyloma, anal warts, and adult or juvenile papillomatosis, which are directly attributable to subtypes HPV 6 and HPV 11. We aim to estimate the prevalence of genital wart infections in men in the US population using a nationwide sample. METHODS: The NHANES database was queried for all men aged 18 to 59 years during the years 2013 to 2014...
June 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29742003/epidemiological-characteristics-and-laboratory-findings-of-zika-virus-cases-in-new-york-city-january-1-2016-june-30-2017
#20
Emily McGibbon, Morgan Moy, Neil M Vora, Alan Dupuis, Annie Fine, Karen Kulas, Ronald Limberger, Dakai Liu, Jennifer Rakeman, Kirsten St George, Sally Slavinski
BACKGROUND: An outbreak of Zika virus (ZIKV) began in May 2015 in Brazil and rapidly spread throughout the Americas; New York City (NYC) has a diverse population with ∼1.8 million residents who were born in ZIKV-affected areas. Before July 24, 2017, the Centers for Disease Control and Prevention (CDC) ZIKV testing recommendations included nucleic acid amplification-based tests for serum and urine specimens collected ≤14 days of illness onset or last potential exposure, and ZIKV immunoglobulin M (IgM) assay when ZIKV RNA is not detected or for specimens collected within 2-12 weeks of illness onset or last potential exposure, followed by a plaque reduction neutralization test (PRNT)...
May 9, 2018: Vector Borne and Zoonotic Diseases
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