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https://www.readbyqxmd.com/read/29667933/a-cbct-study-of-the-gravity-induced-movement-in-rotating-rabbits
#1
Jeffrey Barber, Chun-Chien Shieh, William Counter, Jonathan R Sykes, Peter Bennett, Verity Ahern, Stéphanie Corde, Soo-Min Heng, Paul White, Michael Jackson, Paul Liu, Paul J Keall, Ilana Feain
Fixed-beam radiotherapy systems with subjects rotating about a longitudinal (horizontal) axis are subject to gravity-induced motion. Limited reports on the degree of this motion, and any deformation, has been reported previously. The purpose of this study is to quantify the degree of anatomical motion caused by rotating a subject around a longitudinal axis, using cone-beam CT (CBCT). 
 
 In the current study, a purpose-made longitudinal rotating was aligned to a Varian TrueBeam kV imaging system...
April 18, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29667908/the-macula-densa-prorenin-receptor-is-essential-in-renin-release-and-blood-pressure-control
#2
Anne D M Riquier-Brison, Arnold Sipos, Ágnes Prókai, Sarah L Vargas, Ildiko Toma, Elliott J Meer, Karie G Villanueva, Jennifer C M Chen, Georgina Gyarmati, Christopher Yih, Elaine Tang, Bahram Nadim, Sujith Pendekanti, Ingrid M Garrelds, Genevieve Nguyen, A H Jan Danser, Janos Peti-Peterdi
The prorenin receptor (PRR) was originally proposed to be a member of the renin-angiotensin system (RAS), however recent work questioned their association. The present paper describes a functional link between the PRR and RAS in the renal juxtaglomerular apparatus (JGA), a classic anatomical site of the RAS. PRR expression was found in the sensory cells of the JGA, the macula densa (MD), and immunohistochemistry localized PRR to the MD basolateral cell membrane in mouse, rat, and human kidneys. MD cell PRR activation led to MAP kinase ERK1/2 signaling and stimulation of PGE2 release, the classic pathway of MD-mediated renin release...
April 18, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29667644/emotional-distress-as-a-predictor-of-work-related-musculoskeletal-disorders-in-malaysian-nursing-professionals
#3
Nur Azma Amin, Kia Fatt Quek, Jennifer Anne Oxley, Rahim Noah, Rusli Nordin
BACKGROUND: Emotional distress is becoming a great concern and is more common in both developed and developing countries. It is associated with several disease conditions. OBJECTIVE: To determine the prevalence of self-perceived emotional distress and its relation to work-related musculoskeletal disorders (WRMSDs) in nurses. METHODS: A self-administered questionnaire survey was carried out on 660 female nurses working in public hospitals in the Klang Valley, Malaysia...
April 2018: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29667639/-a-change-in-the-direction-of-the-wound-channel-in-the-case-of-the-combined-injury-inflicted-by-a-shot-from-the-9-0-mm-makarov-pistol
#4
A A Gusarov, I Yu Makarov, V A Fetisov
The authors present an example from the expert practice demonstrating the influence of such factors as the properties of the ammunition fired from a weapon (including its weight, size, shape, and speed) as well as the anatomical features of the body tissues being affected on the mechanism of formation of a gunshot wound in the human body. The investigation of the suicide of subject P. has demonstrated the penetrating bullet wound of the neck and the head. The entrance wound was located at the anterior neck surface and the exit one in the left half of the occipital region...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667201/functioning-of-potassium-and-magnesium-in-photosynthesis-photosynthate-translocation-and-photoprotection
#5
Merle Tränkner, Ershad Tavakol, Bálint Jákli
Potassium (K) and magnesium (Mg) are mineral nutrients that are required in large quantities by plants. Both elements critically contribute to the process of photosynthesis and the subsequent long-distance transport of photoassimilates. If K or Mg are not present in sufficient quantities in photosynthetic tissues, complex interactions of anatomical, physiological and biochemical responses result in a reduction of photosynthetic carbon assimilation. As a consequence, excessive production of reactive oxygen species causes photooxidation of the photosynthetic apparatus and cause an up-regulation of photoprotective mechanisms...
April 18, 2018: Physiologia Plantarum
https://www.readbyqxmd.com/read/29667170/cone-synapses-in-mammalian-retinal-rod-bipolar-cells
#6
Ji-Jie Pang, Zhuo Yang, Roy A Jacoby, Samuel M Wu
Some mammalian rod bipolar cells (RBCs) can receive excitatory chemical synaptic inputs from both rods and cones (DBCR2 ), but anatomical evidence for mammalian cone-RBC contacts has been sparse. We examined anatomical cone-RBC contacts using neurobiotin (NB) to visualize individual mouse cones and standard immuno-markers to identify RBCs, cone pedicles and synapses in mouse and baboon retinas. Peanut agglutinin (PNA) stained the basal membrane of all cone pedicles, and mouse cones were positive for red/green (R/G)-opsin, whereas baboon cones were positive for calbindin D-28k...
April 18, 2018: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29667029/congenital-absence-of-the-internal-carotid-artery-with-a-persistent-primitive-trigeminal-artery-as-a-collateral-pathway-a-report-of-an-anatomic-variation
#7
Dasom Kim, Jin Wook Baek, Young Jin Heo, Hae Woong Jeong
Congenital absence of the internal carotid artery (ICA) is rare, and patients with such a condition are often asymptomatic throughout their lifetime, because of sufficient collateral circulation. Collateral flow is provided via various channels; however, the role of persistent embryonic vessels under conditions in which the ICA is absent or occluded is unknown. We report a rare case of congenital absence of the left ICA and describe the collateral pathway consisting of a persistent trigeminal artery.
April 17, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29666994/whole-body-mri-in-spondyloarthritis-spa-preliminary-results-suggest-that-dwi-outperforms-stir-for-lesion-detection
#8
Frederic E Lecouvet, Nicolas Vander Maren, Laurence Collette, Nicolas Michoux, Perrine Triqueneaux, Maria Stoenoiu, Frederic Houssiau, Jacques Malghem, Marie-Laurence Denis, Ahmed Larbi, Adrien Nzeusseu Toukap
PURPOSE: To compare the diagnostic accuracy of DWI and STIR sequences in Whole body (WB) MRI of SpA patients. MATERIALS AND METHODS: Twenty consecutive patients with confirmed active SpA and 20 controls were investigated with identical WB MRI protocols, including DWI and STIR images. Two observers recorded 'lesions' (high signal intensity foci on STIR and high b-value DWI) in 17 anatomical areas, making a 17-point 'area score' and a 40-point 'lesion score'. ROC performance, inter-observer agreement, correlation with clinical parameters and spine and sacro-iliac joints (SIJ) MRI scores were assessed...
April 17, 2018: European Radiology
https://www.readbyqxmd.com/read/29666963/minimally-invasive-surgery-and-percutaneous-surgery-of-the-hindfoot-and-midfoot
#9
Yves Stiglitz, Cyrille Cazeau
Minimally invasive surgery (MIS) and percutaneous (PC) surgery recently spread as a new technique in operative forefoot correction, and by extension in hindfoot and midfoot. Numerous procedures were described, and a race for MIS and PC has started. However, performing surgery with small incisions should not be an end in itself. Biomechanical and anatomical concerns must be taken into account and shall not be sacrificed for cosmetic reasons. For the most common hindfoot and midfoot pathologies, we discuss what we consider the surgical necessities and then describe the MIS and/or PC procedure we choose, according to these fundamentals...
April 17, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29666910/ontogeny-and-development-of-the-tritocerebral-commissure-giant-tcg-an-identified-neuron-in-the-brain-of-the-grasshopper-schistocerca-gregaria
#10
George Stephen Boyan, Leslie Williams, Tobias Müller, Jonathan P Bacon
The tritocerebral commissure giant (TCG) of the grasshopper Schistocerca gregaria is one of the best anatomically and physiologically described arthropod brain neurons. A member of the so-called Ventral Giant cluster of cells, it integrates sensory information from visual, antennal and hair receptors, and synapses with thoracic motor neurons in order to initiate and regulate flight behavior. Its ontogeny, however, remains unclear. In this study, we use bromodeoxyuridine incorporation and cyclin labeling to reveal proliferative neuroblasts in the region of the embryonic brain where the ventral giant cluster is located...
April 17, 2018: Development Genes and Evolution
https://www.readbyqxmd.com/read/29666842/aesthetic-dental-procedures-legal-and-medico-legal-implications
#11
Pierpaolo Di Lorenzo, Claudia Casella, Emanuele Capasso, Paola Delbon, Piergiorgio Fedeli, Fabio Policino, Massimo Niola
Dental treatments, as well as simple anatomical and functional repair work, can also be for aesthetic purposes. This is because the anatomical area concerned, i.e. the oral cavity, has a great power of attraction. Aesthetic treatments in general - in particular dental treatments - have been on the rise in recent years, and this has also meant an increase in claims due to patient dissatisfaction with the results obtained. Numerous laws have been introduced that emphasise the need for comprehensive prior information in order to acquire valid consent...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29666810/the-8-th-tnm-edition-for-lung-cancer-a-critical-analysis
#12
REVIEW
Paul E Van Schil, Ramon Rami-Porta, Hisao Asamura
The 8th edition of the tumor, node and metastasis (TNM) classification provides several new categories and for the first time, some prospective data are included. The T (tumor) descriptor is further subdivided with 1 cm increments for T1 and T2 disease. For metastatic disease (M descriptor) the new M1b category comprises patients with only one metastasis in one distant organ, whereas M1c implies multiple distant metastases in one or several organs. There are no changes regarding the nodal map and N component but new categories are suggested for further analysis, subdividing the N1 and N2 descriptors into involvement of single or multiple lymph node stations...
March 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29666777/injury-of-the-radial-nerve-in-the-arm-a-review
#13
REVIEW
Taroob J Latef, Muhammad Bilal, Marc Vetter, Joe Iwanaga, Rod J Oskouian, R Shane Tubbs
Compression of the radial nerve is most commonly described at the supinator muscle (i.e., arcade of Frohse). However, radial nerve compression can occur in the arm. Therefore, the purpose of this article is to review both etiologies of radial nerve entrapment and the sites at which this can occur in the arm. The clinical presentation of radial nerve entrapment in the arm and how it differs from that of entrapment at other sites is reviewed and the conditions potentially predisposing to nerve entrapment are described...
February 16, 2018: Curēus
https://www.readbyqxmd.com/read/29666743/an-extremely-rare-bile-leakage-aberrant-bile-duct-in-left-triangular-ligament-appendix-fibrosa-hepatis
#14
İhsan Yıldız, Yavuz Savaş Koca, Sezayi Kantar
Background: The anatomical variability of bile ducts can leave surgeons in very difficult conditions.Ultrasonography, computed tomography, magnetic resonance imaging (MRCP) and endoscopic imaging methods are used in diagnosis. In addition to conservative approaches, endoscopic procedures and laparoscopic or open surgical interventions may be necessary for treatment. In this article, we present a case of aberrant bile duct in left triangular ligament (appendix fibrosa hepatis), which is rarely seen...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29666734/open-reduction-and-internal-fixation-of-a-proximal-femoral-shaft-fracture-in-a-patient-with-bilateral-congenital-hip-disease
#15
Stefania Kanata, Antonios Anastasiadis
We present a rare case of a femoral shaft fracture in a 74-year-old woman with a preexisting untreated bilateral congenital hip dislocation and with concomitant leg length discrepancy. Because of the marked deformity of the upper femur, a derivative of the congenital hip disease, an open reduction and internal fixation was performed, with the use of an anatomic femur plate originally designed for the treatment of periprosthetic fractures. The patient was treated successfully and returned to her previous status of activity...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29666573/psychosocial-stress-and-immunity-what-can-we-learn-from-pig-studies
#16
Ulrike Gimsa, Margret Tuchscherer, Ellen Kanitz
Psychosocial stress may impair immune functions and provoke the development of pathologies. The underlying communication between the brain and the immune system is being studied predominantly in rodents. However, pigs offer several advantages as preclinical models for humans because pigs are more similar to humans than rodents in many anatomical and physiological characteristics. Unlike in rodents, the main stress-induced glucocorticoid in humans and pigs is cortisol with a similar circadian rhythm. In this study, we summarize data on short-term and long-term effects of social stress in pigs for their immunity and neuroendocrine regulation with consequences for their health and well-being...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29666453/epidemiology-and-survival-outcomes-of-mucinous-adenocarcinomas-a-seer-population-based-study
#17
Guang-Dong Xie, Yi-Rong Liu, Yi-Zhou Jiang, Zhi-Ming Shao
To investigate the epidemiology, demographics and survival of mucinous adenocarcinomas (MACs), we identified 80,758 MAC patients in the Surveillance, Epidemiology and End Results (SEER) database. The reported incidence of MACs ebbed and flowed over time; however, a significant increase in reported annual age-adjusted incidences of MACs in the appendix, lung and bronchus was observed from 1981 to 2014. The demographics and outcomes of MACs differed by anatomic sites. MACs of the stomach had the largest percentage of poorly differentiated or undifferentiated tumors (41...
April 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29666271/desynchronization-of-slow-oscillations-in-the-basal-ganglia-during-natural-sleep
#18
Aviv D Mizrahi-Kliger, Alexander Kaplan, Zvi Israel, Hagai Bergman
Slow oscillations of neuronal activity alternating between firing and silence are a hallmark of slow-wave sleep (SWS). These oscillations reflect the default activity present in all mammalian species, and are ubiquitous to anesthesia, brain slice preparations, and neuronal cultures. In all these cases, neuronal firing is highly synchronous within local circuits, suggesting that oscillation-synchronization coupling may be a governing principle of sleep physiology regardless of anatomical connectivity. To investigate whether this principle applies to overall brain organization, we recorded the activity of individual neurons from basal ganglia (BG) structures and the thalamocortical (TC) network over 70 full nights of natural sleep in two vervet monkeys...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29666262/spatial-and-temporal-heterogeneity-of-neural-responses-in-human-posteromedial-cortex
#19
Amy L Daitch, Josef Parvizi
Neuroimaging evidence supports a role of the default mode network (DMN) in spontaneous thought and goal-driven internally oriented processes, such as recalling an autobiographical event, and has demonstrated its deactivation during focused, externally oriented attention. Recent work suggests that the DMN is not a homogeneous network but rather is composed of at least several subnetworks, which are engaged in distinct functions; however, it is still unclear if these different functions rely on the same neuronal populations...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29666087/conservative-treatment-in-displaced-fractures-of-the-humeral-capitellum-a-reduction-technique-under-local-anaesthesia
#20
Takahisa Ogawa, Shinichi Shirasawa
We report the case of a 46-year-old woman who struck her right elbow on the ground after a fall on ice. Radiography showed a right humeral capitellar fracture, and CT further confirmed a Dubberley type 1A fracture. Closed reduction was performed under local anaesthesia, and an anatomical position was obtained. After the reduction, her right elbow was casted for 18 days. Three months after the injury, bone union was achieved without displacement, and the active range of motion of her right elbow recovered similar to the unaffected side...
April 17, 2018: BMJ Case Reports
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