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https://www.readbyqxmd.com/read/27926973/neurologic-injury-in-acidemic-term-infants
#1
Alison G Cahill, Amit M Mathur, Christopher D Smyser, Robert C Mckinstry, Kimberly A Roehl, Julia D López, Terrie E Inder, George A Macones
Objective To determine whether arterial umbilical cord gas (aUCG) pH, in anatomically normal-term infants, could select infants at risk for brain injury identified on magnetic resonance imaging (MRI). Study Design We performed a nested case-control within a prospective cohort of 8,580 women. Cases, with an aUCG pH < 7.10, were temporally, age, and sex matched to controls with an aUCG pH ≥ 7.20. Bi- and multivariable analyses compared the presence and severity of brain injury. Secondary analyses estimated whether elevated arterial base excess or lactate were associated with brain injury...
December 7, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27926970/management-of-endometriosis-involving-the-urinary-tract
#2
Mobolaji O Ajao, Jon I Einarsson
Endometriosis is a common cause of infertility and disabling pelvic pain in reproductive age women. The most widely accepted theory of its pathogenesis is the retrograde flow of menstrual products, although extra-abdominal and extrapelvic diagnoses have been made. After the pelvic peritoneum and gynecologic structures, the most commonly affected sites are the lower gastrointestinal and urinary tracts. When the urinary tract is involved, the bladder is the predominant site, followed by the ureters. The focus of this seminar will thus be these two anatomic sites...
December 7, 2016: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/27926909/dexamethasone-implant-in-chronic-diabetic-macular-edema-resistant-to-intravitreal-ranibizumab-treatment
#3
Ozlem Eski Yucel, Ertugrul Can, Hilal Eser Ozturk, Hakki Birinci, Yuksel Sullu
PURPOSE: The aim of this study was to assess the efficacy of a single intravitreal dexamethasone implant (IDI) over 6 months in eyes with chronic diabetic macular edema (DME) that were resistant to intravitreal ranibizumab (IR) treatment. METHODS: This retrospective study was conducted at the Ondokuz Mayis University Hospital, Samsun, Turkey. Efficacy outcomes were considered as the change from baseline in best corrected visual acuity (BCVA) and central macular thickness (CMT)...
December 8, 2016: Ophthalmic Research
https://www.readbyqxmd.com/read/27926906/long-term-real-life-efficacy-and-safety-of-repeated-ozurdex%C3%A2-injections-and-factors-associated-with-macular-edema-resolution-after-retinal-vein-occlusion-the-remido-2-study
#4
Stéphan Pommier, Franck Meyer, Sébastien Guigou, Tony Barthelemy, Fréderic Gobert, Christian Hajjar, Pierre-Yves Merite, Eric Parrat, Hervé Rouhette, Fréderic Matonti
PURPOSE: The objective was to study long-term real-life efficacy and safety of repeated Ozurdex® injections and factors associated with macular edema (ME) resolution after retinal vein occlusion. METHODS: Patients with ME after retinal vein occlusion, receiving Ozurdex®, were included to assess the following endpoints: visual acuity and central retinal thickness, retreatment, number of injections, side effects and ME resolution. ME resolution was defined as permanent discontinuation of intravitreal injections (IVTs) for at least 6 months after the last IVT...
December 8, 2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27926754/cone-photoreceptor-irregularity-on-adaptive-optics-scanning-laser-ophthalmoscopy-correlates-with-severity-of-diabetic-retinopathy-and-macular-edema
#5
Jan Lammer, Sonja G Prager, Michael C Cheney, Amel Ahmed, Salma H Radwan, Stephen A Burns, Paolo S Silva, Jennifer K Sun
Purpose: To determine whether cone density, spacing, or regularity in eyes with and without diabetes (DM) as assessed by high-resolution adaptive optics scanning laser ophthalmoscopy (AOSLO) correlates with presence of diabetes, diabetic retinopathy (DR) severity, or presence of diabetic macular edema (DME). Methods: Participants with type 1 or 2 DM and healthy controls underwent AOSLO imaging of four macular regions. Cone assessment was performed by independent graders for cone density, packing factor (PF), nearest neighbor distance (NND), and Voronoi tile area (VTA)...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27926556/natural-orifice-specimen-extraction-with-single-stapling-colorectal-anastomosis-for-laparoscopic-anterior-resection-feasibility-outcomes-and-technical-considerations
#6
Bansal Saurabh, Sheng-Chi Chang, Tao-Wei Ke, Yu-Chun Huang, Takashi Kato, Hwei-Ming Wang, William Tzu-Liang Chen, Abe Fingerhut
BACKGROUND: Double and triple stapling techniques to close the rectal stump in laparoscopic anterior resection are fraught with technical drawbacks that could possibly be avoided with the use of the single stapling technique. However, little is known of its safety in laparoscopic surgery or outcomes when combined with natural orifice specimen extraction. OBJECTIVE: This study aims to analyze the feasibility and the operative and immediate postoperative outcomes of single-stapled anastomosis and natural orifice specimen extraction with conventional techniques...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27926554/intraoperative-archive-of-right-colonic-vascular-variability-aids-central-vascular-ligation-and-redefines-gastrocolic-trunk-of-henle-variants
#7
Jamal F Alsabilah, Syed A Razvi, Mahdi H Albandar, Nam K Kim
BACKGROUND: Vascular supply to the right colon has become an issue because of high variability and subsequent impact on minimally invasive surgery. Past cadaveric or radiologic anatomic assessments are noncomprehensive. OBJECTIVE: Intraoperative charting of right colonic arteriovenous anatomy was undertaken to determine the incidence and scope of vascular variations. DESIGN: Vascular anatomy variations were documented in snapshot images, captured during laparoscopic video recordings or through open surgical digital photography...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27926446/how-motivation-and-reward-learning-modulate-selective-attention
#8
A Bourgeois, L Chelazzi, P Vuilleumier
Motivational stimuli such as rewards elicit adaptive responses and influence various cognitive functions. Notably, increasing evidence suggests that stimuli with particular motivational values can strongly shape perception and attention. These effects resemble both selective top-down and stimulus-driven attentional orienting, as they depend on internal states but arise without conscious will, yet they seem to reflect attentional systems that are functionally and anatomically distinct from those classically associated with frontoparietal cortical networks in the brain...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27925595/classification-of-alzheimer-s-disease-using-whole-brain-hierarchical-network
#9
Jin Liu, Min Li, Wei Lan, Fang-Xiang Wu, Yi Pan, Jianxin Wang
Regions of interest (ROIs) based classification has been widely investigated for analysis of brain magnetic resonance imaging (MRI) images to assist the diagnosis of Alzheimer's disease (AD) including its early warning and developing stages, e.g., mild cognitive impairment (MCI) including MCI converted to AD (MCIc) and MCI not converted to AD (MCInc). Since an ROI representation of brain structures is obtained either by pre-definition or by adaptive parcellation, the corresponding ROI in different brains can be measured...
December 2, 2016: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/27925474/fiber-development-and-matrix-production-in-tissue-engineered-menisci-using-bovine-mesenchymal-stem-cells-and-fibrochondrocytes
#10
Mary Clare McCorry, Lawrence J Bonassar
Mesenchymal stem cells (MSCs) have been investigated with promising results for meniscus healing and tissue engineering. While MSCs are known to contribute to ECM production, less is known about how MSCs produce and align large organized fibers for application to tissue engineering the meniscus. The goal of this study was to investigate the capability of MSCs to produce and organize extracellular matrix molecules compared to meniscal fibrochondrocytes (FCCs). Bovine FCCs and MSCs were encapsulated in an anatomically accurate collagen meniscus using mono-culture and co-culture of each cell type...
December 7, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/27925241/vertebral-subluxation-repair-in-a-pet-goat
#11
Sara Nannarone, Enrico Bellezza, Yves P Moens, Paula Larenza Menzies
OBJECTIVES: To describe the perioperative management, including surgery, anesthesia, metabolic derangements, and physiotherapy, in a goat referred for paraparesis secondary to a road traffic accident. STUDY DESIGN: Case report. ANIMALS: 2-year-old mixed breed dwarf 44 kg female pet goat. METHODS: Clinical examination showed symptoms of early compensatory stages of shock, paraparesis with hyperextension of the thoracic limbs, pain on palpation of the thoracolumbar spine, increased patellar reflexes of both pelvic limbs without superficial sensitivity, but preserved deep pain sensation...
December 7, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27925240/closed-reduction-and-fluoroscopic-assisted-percutaneous-pinning-of-42-physeal-fractures-in-37-dogs-and-4-cats
#12
Christina L Boekhout-Ta, Stanley E Kim, Alan R Cross, Antonio Pozzi, Richard Evans
OBJECTIVE: To report complications and clinical outcome of dogs and cats that underwent fluoroscopic-assisted percutaneous pinning (FAPP) of physeal fractures. STUDY DESIGN: Retrospective study. ANIMALS: Client-owned dogs (n = 37) and cats (n = 4). MATERIALS AND METHODS: Records (August 2007-August 2014) of physeal fractures treated with FAPP in 3 hospitals were evaluated. Data collected included signalment, fracture characteristics (etiology, location, duration, Salter-Harris classification, preoperative and postoperative displacement), surgical information (implant size, surgical duration), and outcome assessment information (functional outcome, radiographic outcome, and complications)...
December 7, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27925228/a-mock-circulatory-system-incorporating-a-compliant-3d-printed-anatomical-model-to-investigate-pulmonary-hemodynamics
#13
Paul G M Knoops, Giovanni Biglino, Alun D Hughes, Kim H Parker, Linzhang Xu, Silvia Schievano, Ryo Torii
A realistic mock circulatory system (MCS) could be a valuable in vitro testbed to study human circulatory hemodynamics. The objective of this study was to design a MCS replicating the pulmonary arterial circulation, incorporating an anatomically representative arterial model suitable for testing clinically relevant scenarios. A second objective of the study was to ensure the system's compatibility with magnetic resonance imaging (MRI) for additional measurements. A latex pulmonary arterial model with two generations of bifurcations was manufactured starting from a 3D-printed mold reconstructed from patient data...
December 7, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27924499/pedicle-screw-fixation-with-kyphoplasty-decreases-the-fracture-risk-of-the-treated-and-adjacent-non-treated-vertebral-bodies-a-finite-element-analysis
#14
Pan Yang, Ying Zhang, Huan-Wen Ding, Jian Liu, Lin-Qiang Ye, Jin Xiao, Qiang Tu, Tao Yang, Fei Wang, Guo-Gang Sun
Adjacent vertebral fractures are common in patients with osteoporotic vertebral compression fractures (OVCFs) after kyphoplasty. This finite element study was to examine whether short segment pedicle screw fixation (PSF) with kyphoplasty may decrease the fracture risk of the treated and adjacent non-treated vertebrae after kyphoplasty for OVCFs. By simulating cement augmentation with or without short segment pedicle screw fixation (PSF), two tridimensional, anatomically detailed finite element models of the T10-L2 functional spinal junction were developed...
December 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27924417/surgical-resection-of-skull-base-chordomas-experience-in-case-selection-for-surgical-approach-according-to-anatomical-compartments-and-review-of-the-literature
#15
Nir Shimony, Lior Gonen, Ben Shofty, Avraham Abergel, Dan M Fliss, Nevo Margalit
BACKGROUND: Chordoma is a rare bony malignancy known to have a high rate of local recurrence after surgery. The best treatment paradigm is still being evaluated. We report our experience and review the literature. We emphasize on the difference between endoscopic and open craniotomy in regard to the anatomical compartment harboring the tumor, the limitations of the approaches and the rate of surgical resection. METHOD: We retrospectively collected all patients with skull-base chordomas operated on between 2004 and 2014...
December 6, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27924196/nasogastric-tube-insertion-using-airway-tube-exchanger-in-anesthetized-and-intubated-patients
#16
Hyae-Jin Kim, Hyeon Jeong Lee, Hyun-Jun Cho, Hae-Kyu Kim, Ah-Reum Cho, Narae Oh
BACKGROUND: A nasogastric tube (NGT) is commonly inserted into patients undergoing abdominal surgery to decompress the stomach during or after surgery. However, for anatomic reasons, the insertion of NGTs into anesthetized and intubated patients may be challenging. We hypothesized that the use of a tube exchanger for NGT insertion could increase the success rate and reduce complications. METHODS: One hundred adult patients, aged 20-70 years, who were scheduled for gastrointestinal surgeries with general anesthesia and NGT insertion were enrolled in our study...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27923928/visual-sampling-predicts-hippocampal-activity
#17
Zhong-Xu Liu, Kelly Shen, Rosanna K Olsen, Jennifer D Ryan
: Eye movements serve to accumulate information from the visual world, contributing to the formation of coherent memory representations that support cognition and behaviour. The hippocampus and the oculomotor network are well connected anatomically through an extensive set of polysynaptic pathways. However, the extent to which visual sampling behaviour is related to functional responses in the hippocampus during encoding has not been directly studied in human neuroimaging. In the current study, participants engaged in a face processing task while brain responses were recorded with functional magnetic resonance imaging (fMRI) and eye movements were simultaneously monitored...
December 6, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27923733/cognitive-control-of-vocalizations-in-the-primate-ventrolateral-dorsomedial-frontal-vlf-dmf-brain-network
#18
REVIEW
Loh Kep Kee, Petrides Michael, Hopkins D William, Procyk Emmanuel, Amiez Céline
This review centers on the neural mechanisms underlying the primate cognitive control of vocalizations i.e. the capacity to regulate vocal productions in a goal-directed manner. In both human and non-human primates (NHPs), two main frontal brain regions are associated with top-down vocal control: a ventrolateral frontal region (VLF), comprising the ventrolateral prefrontal cortex and ventral premotor region; and a dorsomedial frontal region (DMF), comprising the mid-cingulate cortex, pre-supplementary and supplementary motor areas...
December 3, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27923664/arhgef1-is-expressed-in-cortical-neural-progenitor-cells-and-regulates-neurite-outgrowth-of-newly-differentiated-neurons
#19
Xiaoliang Xiang, Xiaoji Zhuang, Shengnan Li, Lei Shi
Neurite outgrowth is crucial for the maturation of neurons and the establishment of anatomical connections during development of the nervous system. We report here that Arhgef1, a RhoA guanine nucleotide exchange factor previously found expressed in the early stages of neuronal development to regulate neurite outgrowth, is also highly expressed in cortical neural progenitor cells (NPCs). To better dissect its role in NPCs, we knocked down Arhgef1 expression in these cells and induced differentiated of them into neurons...
December 3, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27923624/a-novel-3d-approach-for-determination-of-frontal-and-coronal-plane-tibial-slopes-from-mr-imaging
#20
Amirhesam Amerinatanzi, Rodney Summers, Kaveh Ahmadi, Vijay K Goel, Timothy E Hewett, Edward Nyman
BACKGROUND: The proximal tibia is geometrically complex, asymmetrical, and variable, is heavily implicated in arthrokinematics of the knee joint, and thus a contributor to knee pathologies such as non-contact anterior cruciate ligament injury. Medial, lateral, and coronal tibial slopes are anatomic parameters that may increase predisposition to knee injuries, but the extent to which each contributes has yet to be fully realized. Previously, two-dimensional methods have quantified tibial slopes, but more reliable 3D methods may prove advantageous...
December 3, 2016: Knee
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