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https://www.readbyqxmd.com/read/28405846/cancer-specific-geriatric-assessment-and-quality-of-life-important-factors-in-caring-for-older-patients-with-aggressive-b-cell-lymphoma
#1
Karin Ribi, Stéphanie Rondeau, Felicitas Hitz, Ulrich Mey, Milica Enoiu, Thomas Pabst, Anastasios Stathis, Natalie Fischer, Kerri M Clough-Gorr
PURPOSE: To evaluate the efficacy and tolerability of chemotherapy, a geriatric assessment is recommended in elderly patients with cancer. We aimed to characterize and compare patients with aggressive lymphoma by objective response and survival status based on pre-treatment cancer-specific geriatric (C-SGA) and quality of life (QoL) assessments. METHODS: Patients not eligible for anthracycline-based first-line therapy or intensive salvage regimens completed C-SGA and QoL assessment before and after a rituximab-bendamustine-lenalidomide (R-BL) treatment in a phase II clinical trial...
April 13, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28369691/adapting-the-vulnerable-elders-survey-13-to-predict-mortality-using-responses-to-the-medicare-health-outcomes-survey
#2
Megan K Beckett, Marc N Elliott, Douglas Ritenour, Laura A Giordano, Susan C Grace, Rochelle Malinoff, Debra Saliba
OBJECTIVES: To use items from the Medicare Health Outcomes Survey (HOS) to adapt or validate a simple method for identifying community-dwelling older adults at greater risk of death and to extend the method to identify a very high-risk group. DESIGN: Analysis of longitudinal data. SETTING: National sample of beneficiaries from Medicare Advantage plans with 500 or more enrollees. PARTICIPANTS: Medicare beneficiaries aged 65 and older responding to 2009 baseline and 2011 follow-up HOS (N = 238,687)...
April 3, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28320329/external-validation-of-the-vulnerable-elder-s-survey-for-predicting-mortality-and-emergency-admission-in-older-community-dwelling-people-a-prospective-cohort-study
#3
Emma Wallace, Ronald McDowell, Kathleen Bennett, Tom Fahey, Susan M Smith
BACKGROUND: Prospective external validation of the Vulnerable Elder's Survey (VES-13) in primary care remains limited. The aim of this study is to externally validate the VES-13 in predicting mortality and emergency admission in older community-dwelling adults. METHODS: Design: Prospective cohort study with 2 years follow-up (2010-2012). SETTING: 15 General Practices (GPs) in the Republic of Ireland. PARTICIPANTS: n = 862, aged ≥70 years, community-dwellers Exposure: VES-13 calculated at baseline, where a score of ≥3 denoted high risk...
March 20, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/27928529/the-effect-of-public-service-advertising-on-cardiovascular-disease-in-korea
#4
Juhyun Jang, Baeg Ju Na, Moo-Sik Lee, Soonryu Seo, Changhyun Sung, Hyun Joo Kim, Jin Yong Lee
BACKGROUND: Public Service Advertising (PSA) is a public interest message disseminated in the form of an advertisement communication and its main purpose is to promote public behavioral changes regarding a social issue. Korea Centers for Disease Control and Prevention (KCDC) has been delivering PSA by various media. However, the effect of PSAs has never been evaluated. The purpose of this study was to estimate the effects of broadcasted PSA produced by KCDC on cardiovascular disease (CVD)...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27756545/a-comparison-of-the-carg-tool-the-ves-13-and-oncologist-judgment-in-predicting-grade-3-toxicities-in-men-undergoing-chemotherapy-for-metastatic-prostate-cancer
#5
Shabbir M H Alibhai, Salman Aziz, Tharsika Manokumar, Narhari Timilshina, Henriette Breunis
OBJECTIVE: Since the benefits of chemotherapy in treating older men with metastatic castration-resistant prostate cancer (mCRPC) are modest, validated tools that predict the risk of treatment toxicity may aid clinical decision-making. Whether these tools are better than oncologist judgment remains unclear. We compared the Cancer and Aging Research Group (CARG) tool, the Vulnerable Elders Survey-13 (VES-13), and oncologist judgment in predicting toxicity in men with mCRPC undergoing chemotherapy...
October 15, 2016: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/27574587/hepatocellular-carcinoma-in-elderly-patients-challenges-and-solutions
#6
REVIEW
Angélique Brunot, Samuel Le Sourd, Marc Pracht, Julien Edeline
Hepatocellular carcinoma (HCC) is the second most common cause of death by cancer in the world. Due to the delayed HCC development in hepatitis C carriers and nonalcoholic fatty liver disease, the incidence of HCC in the elderly is increasing and is becoming a global health issue. Elderly patients with HCC should be assessed through proper oncologic approach, namely, screening tools for frailty (Geriatric-8 or Vulnerable Elders Survey-13) and comprehensive geriatric assessment. This review of the literature supports the same treatment options for elderly patients as for younger patients, in elderly patients selected as fit following proper oncogeriatric assessment...
2016: Journal of Hepatocellular Carcinoma
https://www.readbyqxmd.com/read/27492449/a-profile-of-four-patterns-of-vulnerability-to-functional-decline-in-older-general-medicine-patients-in-victoria-australia-a-cross-sectional-survey
#7
Lenore Beddoes-Ley, Damien Khaw, Maxine Duke, Mari Botti
BACKGROUND: There are limited published data reporting Australian hospitalized elders' vulnerability to functional decline to guide best practice interventions. The objectives of this study were to describe the prevalence of vulnerability to functional decline and explore profiles of vulnerability related to the performance of physical activity in a representative group of elders in a single centre in Victoria, Australia. METHODS: A cross-sectional survey of patients aged ≥ 70 years (Mean age 82...
2016: BMC Geriatrics
https://www.readbyqxmd.com/read/27348765/vulnerable-elders-survey-and-socioeconomic-status-predict-functional-decline-and-death-among-older-women-with-newly-diagnosed-nonmetastatic-breast-cancer
#8
Cynthia Owusu, Seunghee Margevicius, Mark Schluchter, Siran M Koroukian, Kathryn H Schmitz, Nathan A Berger
BACKGROUND: The purpose of this study was to determine the ability of the Vulnerable Elders Survey (VES-13) to predict the composite outcome of functional decline and death within 12 months of breast cancer treatment among women 65 years old or older with newly diagnosed stage I to III breast cancer. METHODS: Two hundred and six participants were recruited from ambulatory oncology clinics at an academic center between April 2008 and April 2013. Participants competed the VES-13 at baseline just before neoadjuvant/adjuvant treatment...
August 15, 2016: Cancer
https://www.readbyqxmd.com/read/27269217/-not-available
#9
REVIEW
María José Molina Garrido
Cada vez es mayor el número de ancianos con diagnóstico de cáncer que acuden a las consultas de Oncología Médica. El proceso del envejecimiento y la gran variabilidad existente en la población geriátrica implican que, para hacer un abordaje adecuado del paciente, se deba considerar la edad fisiológica del anciano, y no su edad biológica. Para ello, es preciso hacer una evaluación somera, específica e individualizada a cada uno de los ancianos con diagnóstico de cáncer que acudan a nuestra consulta...
June 3, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27254472/physiologic-frailty-in-nonelderly-hematopoietic-cell-transplantation-patients-results-from-the-bone-marrow-transplant-survivor-study
#10
Mukta Arora, Can-Lan Sun, Kirsten K Ness, Jennifer Berano Teh, Jessica Wu, Liton Francisco, Saro H Armenian, Amy Schad, Golnaz Namdar, Alysia Bosworth, Linus Kuo, Daniel J Weisdorf, Stephen J Forman, Smita Bhatia
Importance: Frailty results in decreased physiological reserve and diminished resistance to stressors; approximately 10% of those in the elderly population (those ≥65 years) are frail. High-intensity treatments and complications after hematopoietic cell transplantation (HCT) injure normal tissues and may increase the risk of frailty even among nongeriatric HCT patients. Objective: To determine the prevalence of frailty in young adult HCT patients (18- to 64-year-olds) and siblings; and the impact of frailty on subsequent mortality in HCT survivors...
October 1, 2016: JAMA Oncology
https://www.readbyqxmd.com/read/27160741/a-questionnaire-study-to-assess-the-value-of-the-vulnerable-elders-survey-g8-and-predictors-of-toxicity-as-screening-tools-for-frailty-and-toxicity-in-geriatric-cancer-patients
#11
Leopold Hentschel, Anke Rentsch, Felicitas Lenz, Beate Hornemann, Jochen Schmitt, Michael Baumann, Gerhard Ehninger, Markus Schuler
BACKGROUND: The aim of this study was to identify an appropriate screening instrument for the identification of frail elderly patients in a tertiary cancer center. In order to improve cancer care for older patients, the use of a geriatric assessment (GA) has been proposed to identify frail patients or those who are at a higher risk for chemotherapy-related toxicities. In busy clinical routine, an appropriate screening instrument could be used to spare time- and resource-consuming application of GA...
2016: Oncology Research and Treatment
https://www.readbyqxmd.com/read/26910147/self-reported-oral-health-in-the-brazilian-adult-population-results-of-the-2013-national-health-survey
#12
Lucélia Silva Nico, Silvânia Suely Caribé de Araújo Andrade, Deborah Carvalho Malta, Gilberto Alfredo Pucca Júnior, Marco Aurelio Peres
Oral diseases are a relevant public health problem in Brazil, because of their prevalence and magnitude in the population. Population-based surveys are essential tools for the election of groups and demands priority attention, . The aim of this paper was to describe the self-reported oral health status of the population, according to sociodemographic factors. A descriptive study was conducted using the National Health Survey data of 2013. Indicators associated with oral hygiene practices and oral health conditions were analyzed...
February 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/26853769/a-prospective-study-examining-elder-relevant-outcomes-in-older-adults-with-prostate-cancer-undergoing-treatment-with-chemotherapy-or-abiraterone
#13
Tharsika Manokumar, Salman Aziz, Henriette Breunis, S Faraz Rizvi, Anthony M Joshua, Ian F Tannock, Shabbir M H Alibhai
BACKGROUND: Treatment of metastatic castration-resistant prostate cancer (mCRPC) with chemotherapy improves disease control and survival in fit older men (age 65+) but its impact on function is not clear. We hypothesized that chemotherapy would impair daily function in older men with mCRPC. METHODS: Men aged 65+ with mCRPC starting chemotherapy or abiraterone were enrolled in this prospective observational pilot study. Daily function was evaluated with the OARS Instrumental Activities of Daily Living (IADL) scale...
March 2016: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/26779367/how-to-select-elderly-colorectal-cancer-patients-for-surgery-a-pilot-study-in-an-italian-academic-medical-center
#14
Giampaolo Ugolini, Francesco Pasini, Federico Ghignone, Davide Zattoni, Maria Letizia Bacchi Reggiani, Daniele Parlanti, Isacco Montroni
OBJECTIVE: Cancer is one of the most common diagnoses in elderly patients. Of all types of abdominal cancer, colorectal cancer (CRC) is undoubtedly the most frequent. Median age at diagnosis is approximately 70 years old worldwide. Due to the multiple comorbidities affecting elderly people, frailty evaluation is very important in order to avoid over- or under-treatment. This pilot study was designed to investigate the variables capable of predicting the long-term risk of mortality and living situation after surgery for CRC...
December 2015: Cancer Biology & Medicine
https://www.readbyqxmd.com/read/26700296/attitudes-of-older-adults-with-serious-competing-health-risks-toward-their-implantable-cardioverter-defibrillators-a-pilot-study
#15
Ariel R Green, Cynthia M Boyd, John Rickard, Robert Gomon, Bruce Leff
BACKGROUND: In elderly heart failure patients, the survival benefit of implantable cardioverter-defibrillators (ICDs) may be attenuated due to competing health risks, and the risk of adverse outcomes magnified. Our objective was to examine older adults' attitudes towards ICD implantation in the context of competing health risks, exploring the determinants of ICD decision-making among a group of patients who had faced the decision in the past. METHODS: Telephone survey with a qualitative component...
2015: BMC Geriatrics
https://www.readbyqxmd.com/read/26656521/screening-performance-for-frailty-among-older-patients-with-cancer-a-cross-sectional-observational-study-of-two-approaches
#16
Toru Okuyama, Koji Sugano, Shinsuke Iida, Takashi Ishida, Shigeru Kusumoto, Tatsuo Akechi
OBJECTIVES: To investigate the screening performance for frailty of the Vulnerable Elders Survey-13 (VES-13) and the 2-step approach consisting of the VES-13 plus the anhedonia (loss of interest or pleasure) item from Patient Health Questionnaire-9 (PHQ-9) among older patients with newly diagnosed cancer. METHODS: This study involved 106 consecutive inpatients aged 65 years or older, newly diagnosed with malignant lymphoma or multiple myeloma, just before chemotherapy initiation...
December 2015: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/26509461/self-reported-outcomes-in-individuals-aged-65-and-older-admitted-for-treatment-to-an-acute-care-surgical-service-a-6-month-prospective-cohort-study
#17
Talal F Ali, Lindsey M Warkentin, Sayf Gazala, Adrian S Wagg, Raj S Padwal, Rachel G Khadaroo
OBJECTIVES: To examine health-related quality of life (HRQL) and cognitive and functional status before and after emergency surgical care in elderly adults. DESIGN: Six-month prospective cohort study. SETTING: Acute care and emergency surgery service at a single, academic tertiary care center, Edmonton, Alberta, Canada. PARTICIPANTS: Admitted individuals aged 65 and older (mean age 77.8 ± 7.9, 52% female) or their surrogates...
November 2015: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/26488196/economic-impact-of-using-fesoterodine-for-the-treatment-of-overactive-bladder-with-urge-urinary-incontinence-in-a-vulnerable-elderly-population-in-the-united-states
#18
Lei Qin, Xuemei Luo, Kelly H Zou, Sonya J Snedecor
OBJECTIVES: To assess the costs of treating overactive bladder (OAB) with fesoterodine compared to no OAB pharmacotherapy among vulnerable elderly from the US payer perspective. METHODS: A decision analytic cost model was developed to estimate the 52-week costs of a cohort of vulnerable elderly with OAB initiating treatment with fesoterodine or no OAB pharmacotherapy. Vulnerable elderly OAB patients were defined as those aged ≥65 years with self-reported urge urinary incontinence (UUI) symptoms for ≥3 months, 2-15 UUI episodes/day, and at risk of deteriorating health by a score of ≥3 on the Vulnerable Elders Survey (VES)-13...
2016: Journal of Medical Economics
https://www.readbyqxmd.com/read/26475578/vulnerability-in-elderly-patients-with-gastrointestinal-cancer-translation-cultural-adaptation-and-validation-of-the-european-portuguese-version-of-the-vulnerable-elders-survey-ves-13
#19
F Carneiro, N Sousa, L F Azevedo, D Saliba
BACKGROUND: "Vulnerable Elders Survey" (VES-13) is a questionnaire accurate in predicting functional decline and highly correlated with comprehensive geriatric assessment in identifying vulnerable elderly. The purpose of this study was to translate, cultural adapt and validate the first Portuguese cross-cultural version of VES-13 and to estimate the prevalence of vulnerability in Portuguese elderly gastrointestinal (GI) cancer patients. METHODS: VES-13 European Portuguese translation and cultural adaptation was developed according to internationally accepted guidelines...
2015: BMC Cancer
https://www.readbyqxmd.com/read/26369366/geriatric-disaster-preparedness
#20
Mary Colleen Bhalla, Amos Burgess, Jennifer Frey, William Hardy
INTRODUCTION: The elderly population has proven to be vulnerable in times of a disaster. Many have chronic medical problems for which they depend on medications or medical equipment. Some older adults are dependent on caregivers for managing their activities of daily living (ADLs), such as dressing, and their instrumental activities of daily living (IADLs), such as transportation. Problem A coordinated effort for disaster preparation in the elderly population is paramount. This study assessed the potential needs and plans of older adults in the face of a local disaster...
October 2015: Prehospital and Disaster Medicine
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