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health related quality of life transplant

Yuki Yoshikawa, Junji Uchida, Chiharu Akazawa, Nobuhiko Suganuma
Purpose: Health-related quality of life (HRQOL) among kidney transplant recipients is associated with physical and psychosocial characteristics. Furthermore, pregnancy and childcare may be particularly challenging for women. The aim of this study was to assess the relationship between patients' psychosocial characteristics and HRQOL, specifically for recipients who have given birth after their kidney transplant. Patients and methods: This was a cross-sectional study...
2018: International Journal of Women's Health
Neel S Bhatt, Ruta Brazauskas, Heather R Tecca, Jenny Vogel, Deborah Mattila, Stephanie J Lee, Mary M Horowitz, J Douglas Rizzo, Bronwen E Shaw
To study the factors associated with poorer health-related quality of life at 1-year post-allogeneic hematopoietic cell transplantation (alloHCT), a secondary analysis of a prospective feasibility study was performed. Pediatric Quality of Life Inventory questionnaires were collected in 76 children undergoing alloHCT at baseline (within 30 d before transplantation), day 100, 6 months, and 12 months posttransplantation. The global score improved post-HCT (baseline: 67.1, 12 mo: 76.6). Females (odds ratio, 6...
June 19, 2018: Journal of Pediatric Hematology/oncology
Linbo Wei, Juan Li, Yanpei Cao, Jianming Xu, Wei Qin, Huijuan Lu
So far, liver transplantation (LT) has become the most effective way to treat end-stage liver-related diseases. As we all know, a stable caregiver is crucial to LT recovery. However, compared with LT patients, few studies were focused on LT caregivers.This study aimed to describe the quality of life (QoL), care burden, and their related factors in caregivers of LT patients in Shanghai, China.We collected 225 liver transplanted patients and their corresponding caregivers' social demographic and medical information; meanwhile, we assessed 225 LT recipients' caregivers' life quality; by using Caregiver Quality of Life Index-Liver Transplantation in Chinese version (CQOLC-LT), Zarit caregiver burden inventory in Chinese version (ZBI) was used to access the care burden...
June 2018: Medicine (Baltimore)
Zhenshun Wang, Ning Li, Dongdong Lin
Objective The incidence of metabolic syndrome (MS) increases after liver transplantation. This study was performed to evaluate the impact of MS on patients' quality of life after liver transplantation. Methods We collected the medical records of 152 patients during their post-liver transplantation outpatient follow-up. Quality of life was assessed using the Medical Outcomes Study 36-Item Short Form Health Survey. Data on the patients' general condition as well as MS-related indicators were assessed in all patients...
January 1, 2018: Journal of International Medical Research
Q He, J J Jiang, Y X Jiang, W T Wang, L Yang
BACKGROUND: For cancer patients, health-related quality of life (HRQoL) is as important as other key outcomes, such as overall survival and tumor-free survival. Liver transplantation (LT), resection, and radiofrequency ablation (RFA) are 3 radical therapies for hepatocellular carcinoma (HCC) that result in similar survival. The main objective of this study was to assess and compare long-term HRQoL scores for patients with early-stage (tumor diameter ≤3 cm) HCC after LT, resection, or RFA...
June 2018: Transplantation Proceedings
Megan L Oser, Marie-Christine Nizzi, Jennifer L Zinser, Marvee Turk, Russell Epstein, Ericka Bueno, David Gitlin, Bohdan Pomahac
BACKGROUND: Face transplantation is a novel option for patients with severe facial disfigurement. Quality of life (QoL) outcomes of face transplantation remain poorly understood. OBJECTIVES: We sought to evaluate psychosocial functioning among 6 patients undergoing facial transplantation. METHODS: We prospectively assessed depressive symptoms, health status, mental and physical QoL, and self-esteem at 3-month intervals for 2 years. Social desirability was assessed pretransplant...
April 20, 2018: Psychosomatics
Peter Esser, Katharina Kuba, Anja Mehnert, Christoffer Johansen, Andreas Hinz, Florian Lordick, Heide Götze
OBJECTIVES: Quality of life (QoL) has become an important tool to guide decision making in oncology. Given the heterogeneity among hematological cancer survivors, however, clinicians need comparative data across different subsets. METHODS: This study recruited survivors of hematological malignancies (≥ 2.5 years after diagnosis) from two German cancer registries. QoL was assessed with the EORTC QLQ-C30. The sample was stratified by cancer type, time since diagnosis, treatment with stem cell transplantation (SCT) and type of SCT...
June 1, 2018: European Journal of Haematology
Athanasios Tyraskis, Christopher Parsons, Mark Davenport
BACKGROUND: Biliary atresia is a life-threatening disease characterised by progressive destruction of both intra- and extra-hepatic biliary ducts. The mainstay of treatment is Kasai portoenterostomy, as soon as the disease has been confirmed. Glucocorticosteroids are steroid hormones which act on the glucocorticoid receptor and have a range of metabolic and immunomodulatory effects. Glucocorticosteroids are used to improve the postoperative outcomes in infants who have undergone Kasai portoenterostomy...
May 14, 2018: Cochrane Database of Systematic Reviews
Marit S van Sandwijk, Doaa Al Arashi, Fons M van de Hare, J M Rolien van der Torren, Marie-José Kersten, Joost A Bijlsma, Ineke J M Ten Berge, Frederike J Bemelman
Background: The impact of haemodialysis (HD) and kidney transplantation on quality of life (QoL) is often underestimated due to a lack of comparative studies with other patient groups. Methods: We conducted a cross-sectional cohort study in 168 patients including HD patients, kidney transplant recipients (KTR), patients with a haematological malignancy either receiving chemotherapy or in remission and healthy controls. All participants completed the 36-item short form survey of health-related quality of life, the Checklist Individual Strength and the Hospital Anxiety and Depression Scale questionnaire...
May 2, 2018: Nephrology, Dialysis, Transplantation
Irene Petersen, Anna Sophie Dechow, Karl-Heinz Schulz
Liver transplantation (LTX) is an established therapy for pediatric patients with liver failure. In recent decades, survival rates have risen continuously. With increased life expectancy, there has been greater attention to children's and adolescents' quality of life following transplantation. This article provides an overview of the tasks of pediatric transplant psychology. We summarize the reviewed literature of research on health-related quality of life in pediatric liver transplant recipients. Furthermore, we present studies on fatigue, mental health, cognitive development and family strain...
May 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
Kjersti Lønning, Kristian Heldal, Tomm Bernklev, Cathrine Brunborg, Marit Helen Andersen, Nanna von der Lippe, Anna Varberg Reisæter, Pål-Dag Line, Anders Hartmann, Karsten Midtvedt
Background: We aimed to evaluate changes in health-related quality of life (HRQoL) in patients 65 years or older from time of kidney transplantation (KTx) until 1 year postengraftment. Methods: A single-center prospective study was conducted. HRQoL was measured pre-KTx and at 2, 6, and 12 months postengraftment using self-reported Kidney Disease and Quality of Life short-form version 1.3. Intraindividual scores before and after KTx were evaluated. Liu Comorbidity Index was registered at enlisting...
April 2018: Transplantation Direct
Yosra Mouelhi, Elisabeth Jouve, Marine Alessandrini, Nathalie Pedinielli, Valérie Moal, Aurélie Meurette, Elisabeth Cassuto, Georges Mourad, Antoine Durrbach, Bertrand Dussol, Stéphanie Gentile
BACKGROUND: Health-Related Quality of Life (HRQoL) assessment after kidney transplantation has become an important tool in evaluating outcomes. This study aims to identify the associated factors with HRQoL among a representative sample size of Kidney Transplant Recipients (KTR) at the time of their inclusion in the study. METHODS: Data of this cross-sectional design is retrieved from a longitudinal study conducted in five French kidney transplant centers in 2011, and included KTR aged 18 years with a functioning graft for at least 1 year...
April 27, 2018: BMC Nephrology
Danilo Carrozzino, Piero Porcelli
Background: Alexithymia is a multifaceted personality construct that represents a deficit in the cognitive processing of emotions and is currently understood to be related to a variety of medical and psychiatric conditions. The present review aims to investigate the relationship of alexithymia with gastrointestinal (GI) disorders as functional gastrointestinal disorders (FGID, as irritable bowel syndrome (IBS) and functional dyspepsia) and inflammatory bowel disease (IBD) [ulcerative colitis (UC) and Crohn's disease (CD)] and liver diseases as chronic hepatitis C (CHC), cirrhosis, and liver transplantation...
2018: Frontiers in Psychology
Nacho Castejón, Joseph C Cappelleri, Jesús Cuervo, Kathryn Lang, Priyanka Mehta, Ruth Mokgokong, Carla Mamolo
BACKGROUND: Health state (HS) utility values for patients with acute myeloid leukemia (AML), a hematological malignancy, are not available in the United Kingdom (UK). This study aims to develop clinically sound HSs for previously untreated patients with AML and to assign utility values based on preferences of the general UK population. METHODS: This study was conducted in the UK and comprised 2 stages. During the first stage, AML HSs were drafted based on evidence from a literature review of AML clinical and health-related quality-of-life studies (published January 2000-June 2016) and patient-reported outcome measures previously used in this population...
April 18, 2018: Health and Quality of Life Outcomes
Rajshekhar Chakraborty, Betty K Hamilton, Shahrukh K Hashmi, Shaji K Kumar, Navneet S Majhail
Autologous stem cell transplantation (ASCT) is an integral part of the frontline therapy in eligible multiple myeloma (MM) patients. The impact of ASCT on health-related quality of life (HRQoL) in myeloma has not been well described. We performed a systematic literature search to identify studies evaluating the impact of ASCT on HRQoL. Our search retrieved 12 relevant studies: 10 manuscripts and 2 conference abstracts. There was a widespread heterogeneity across studies in instruments used to measure HRQoL, time points of measurement, and statistical analysis...
April 4, 2018: Biology of Blood and Marrow Transplantation
Agatha M Gallo, Crystal Patil, Tokunbo Adeniyi, Lewis L Hsu, Damiano Rondelli, Santosh Saraf
Allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen (HLA)-matched sibling donor offers a unique therapy to reverse SCD. This mixed-methods study explores recipients' perception of HSCT success, personal life goals, and associated health-related quality of life (HRQOL) more than 1 year after HSCT. Recipients completed the Short Form-36, version 1 (SF-36v1) HRQOL survey followed by a 60- to 90-min face-to-face or telephone audio-recorded interview. Eleven of 15 eligible recipients participated in the study...
April 1, 2018: Western Journal of Nursing Research
Ryul Kim, Kyung-Lak Son, Kwang-Min Lee, Younak Choi, Junshik Hong, Dong-Yeop Shin, Youngil Koh, Bong-Jin Hahm, Inho Kim
This prospective longitudinal study evaluated the temporal trajectory of health-related quality of life (HRQOL) and its associated factors in patients who received hematopoietic stem cell transplantation (SCT) 6 months after transplantation. Eighty-nine adult patients who were admitted to Seoul National University Hospital for SCT were consecutively included in the study. The participants completed three standardized questionnaires: Insomnia Severity Index, Hospital Anxiety and Depression Scale, and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire...
April 3, 2018: Annals of Hematology
Yongchun Liang, Haifang Wang, Meie Niu, Xiaming Zhu, Jianzheng Cai, Xiubei Wang
OBJECTIVES: The aim of our longitudinal study was to explore changes in HRQOL over a 6-month period and to identify factors associated with the HRQOL of HSCT recipients. METHOD: Our study comprised 191 HSCT patients; their data were collected before transplantation and at 30, 90, and 180 days posttransplantation. The Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) questionnaire was used to assess HRQOL.We also evaluated the patients' demographic characteristics and clinical histories to determine the relative contributions of these factors to HRQOL outcomes...
March 27, 2018: Hematology (Amsterdam, Netherlands)
Katrina A Bramstedt
This study is a long-term follow-up on the health and quality of life of Good Samaritan living organ donors who donated an average of 10 years ago. Thirteen donors (kidney, liver, and lung) completed 2 surveys. Data from the RAND 36-Item Health Survey showed that for all domains, as well as the physical and mental component summary scales, the Good Samaritan donor outcomes were superior to the general population ( P < .0001). Data from the European Living Donor Satisfaction Survey (EULID) showed that in all 8 theme areas, the donors reported statistically significant positive reactions as compared to negative reactions...
March 2018: Journal of Patient Experience
Nicholas A Kolaitis, Jonathan P Singer
Lung transplantation (LT) has the potential to extend survival and improve quality of life (QOL) for patients suffering from end-stage lung disease. This review describes the many ways in which success can be defined in LT. It evaluates the improvements in survival outcomes after LT over time, and describes ways to measure the success of LT other than survival after transplantation. It also addresses the importance of patient-centered outcomes and how improvements in health-related quality of life (HRQL) are pivotal to defining success within LT...
April 2018: Seminars in Respiratory and Critical Care Medicine
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