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health related quality of life transplant

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https://www.readbyqxmd.com/read/28090226/more-use-of-peritoneal-dialysis-gives-significant-savings-a-systematic-review-and-health-economic-decision-model
#1
Eva Pike, Vida Hamidi, Tove Ringerike, Torbjorn Wisloff, Marianne Klemp
BACKGROUND: Patients with end-stage renal disease (ESRD) are in need of renal replacement therapy as dialysis and/or transplantation. The prevalence of ESRD and, thus, the need for dialysis are constantly growing. The dialysis modalities are either peritoneal performed at home or hemodialysis (HD) performed in-center (hospital or satellite) or home. We examined effectiveness and cost-effectiveness of HD performed at different locations (hospital, satellite, and home) and peritoneal dialysis (PD) at home in the Norwegian setting...
February 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28065646/-what-the-family-doctor-must-know-about-lung-transplantation-complications-health-promotion-and-outcomes-part-2
#2
L Zurbano, F Zurbano
The lung transplantation is a therapeutic procedure indicated for lung diseases that are terminal and irreversible (except lung cancer) despite the best medical current treatment. It is an emergent procedure in medical care. In this review, an analyse is made of the most frequent complications of lung transplant related to the graft (rejection and chronic graft dysfunction), immunosuppression (infections, arterial hypertension, renal dysfunction, and diabetes), as well as others such as gastrointestinal complications, osteoporosis...
January 5, 2017: Semergen
https://www.readbyqxmd.com/read/28039882/psycho-social-aspects-before-and-up-to-2-years-after-heart-or-lung-transplantation-experience-of-patients-and-their-next-of-kin
#3
Susanna Ågren, Trygve Sjöberg, Björn Ekmehag, Maj-Britt Wiborg, Bodil Ivarsson
BACKGROUND: Psychosocial factors are important for patients undergoing heart (HTx) or lung (LTx) transplantation, and for their next of kin (NoK). AIM: To describe health-related quality of life (patients only), anxiety, depression, stress, coping ability and burden (NoK only) for patients and their NoK before and up to 2 years after HTx or LTx. DESIGN: Adult patients (28 heart and 26 lung) and their appointed NoK were surveyed with questionnaires about specific psychosocial topics when they were accepted for the transplantation waiting list and 6 months, 1 year, and 2 years after transplantation...
December 31, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/28006876/health-related-quality-of-life-after-pediatric-liver-transplantation-a-systematic-review
#4
REVIEW
Arpita Parmar, Shannon Marie Vandriel, Vicky Lee Ng
With improved survival rates after pediatric liver transplantation (LT), attention is targeting improving the health-related quality of life (HRQOL) as an outcome metric. We conducted a systematic review of the literature to examine HRQOL after pediatric LT, focusing on assessment tools, and factors associated with HRQOL.A literature search was conducted through PubMed, Web of Science, OVID, and Google Scholar for all studies matching the eligibility criteria between January 2004 and September 2016. Titles and abstracts were screened independently by two authors and consensus for included studies was achieved through discussion...
December 22, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/28002881/assessing-the-clinical-and-economic-impact-of-increasing-treatment-uptake-in-chronic-hepatitis-b-infection-using-a-markov-model
#5
Mohamed A Chinnaratha, Billingsley Kaambwa, Richard J Woodman, Robert J Fraser, Alan J Wigg
: Treatment uptake in chronic hepatitis B virus (HBV) infection is low in South Australia and the cost-effectiveness of increasing treatment uptake rates in this population has not been assessed. AIMS & METHODS: Using a cohort Markov model, cost-effectiveness was assessed for 3 different treatment uptake scenarios: 2.9% (current level -scenario 1), 10% (Scenario 2) and 15% (Scenario 3). The initial HBV population included 2550 treatment eligible patients who transitioned between six different health states over a 10- year period...
December 21, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27997676/development-of-a-predictive-model-for-drug-related-problems-in-kidney-transplant-recipients
#6
Kelly L Covert, Caitlin R Mardis, James N Fleming, Nicole A Pilch, Holly B Meadows, Benjamin A Mardis, Prince Mohan, Maria Posadas-Salas, Titte Srinivas, David J Taber
STUDY OBJECTIVE: Drug-related problems (DRPs) are associated with increased rates of infection, rejection, and graft loss in kidney transplant recipients. This study aimed to develop a model to predict which patients are at highest risk of DRPs to streamline pharmacists' workflow in a chronic kidney transplant clinic. DESIGN: Prospective observational study. SETTING: Chronic kidney transplant clinic at a large, tertiary care, academic hospital...
December 20, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27969024/accuracy-of-anxiety-and-depression-screening-tools-in-heart-transplant-recipients
#7
Aaron Conway, Judith Sheridan, Joanne Maddicks-Law, Paul Fulbrook, Chantal F Ski, David R Thompson, Lynn V Doering
PURPOSE: The aim of this study was to assess the validity and reliability of psychological screening tools in outpatient heart transplant recipients. METHODS: Forty-eight heart transplant recipients completed the Patient Health Questionnaire 9-item scale (PHQ-9), Generalized Anxiety Disorder 7-item Scale (GAD-7), Kessler Psychological Distress 10-item Scale (K-10) and Medical Outcomes Short Form 36-item Health Survey. A structured psychological interview (Mini International Neuropsychiatric Interview Version 6) was conducted after completion of the questionnaires...
November 2016: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/27966317/health-related-quality-of-life-of-pediatric-renal-transplant-recipientsand-their-parents-the-role-of-associated-factors-and-clinical-counseling
#8
Bahar Büyükkaragöz, Necla Buyan, Nahide Doğrucan, Bülent Çelik
BACKGROUND/AIM: This study evaluates the health-related quality of life (HRQoL) of pediatric renal transplant recipients and their parents and investigates the effects of clinical, socioeconomic, and psychological factors as well as continuous counseling on the HRQoL. MATERIALS AND METHODS: Patients aged 8-17 years (mean: 14.9 ± 2.9) were enrolled. Clinical and demographic data were noted. The Beck Depression Inventory (BDI), Rosenberg Self-Esteem Scale (RSES), and Turkish version of the Kinder Lebensqualität Fragebogen (KINDL) questionnaire for children and the BDI, RSES, parent-proxy version of KINDL, and Short-Form 36 (SF-36) for parents were applied (step 1)...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27941441/live-donors-of-the-initial-observational-study-of-uterus-transplantation-psychological-and-medical-follow-up-until-1-year-after-surgery-in-the-9-cases
#9
Niclas Kvarnström, Stina Järvholm, Liza Johannesson, Pernilla Dahm-Kähler, Michael Olausson, Mats Brännström
BACKGROUND: The first prospective observational study of uterus transplantation was initiated in 2013 with live donation to 9 women with absolute uterine factor infertility. We explored the medical complications and psychosocial wellbeing of the donors during the first postoperative year. METHODS: Complications were registered and graded according to the Clavien-Dindo (C-D) classification. Symptoms related to the surgery were registered. Data on length of hospital stay, sick leave, socioeconomic parameters and life events were obtained...
December 8, 2016: Transplantation
https://www.readbyqxmd.com/read/27935642/long-term-health-related-quality-of-life-hrqol-in-living-liver-donors-a-south-asian-experience
#10
P Thomas Cherian, Ashish Kumar Mishra, Sm Faisal Mahmood, Mohan Sathyanarayanan, Ravichandra Raya, Venugopal Kota, Mohamed S Rela
: The aim of this study was to evaluate long-term health related quality of life(HRQOL), changes in lifestyle and complications in living liver donors at a single transplant center from southern India. METHODS: 64 consecutive living liver donors from 2008-2011 were evaluated.46 out of 64 donors completed the short form 36(SF-36) via telephonic interviews or clinic consultations. Mean follow up was 48 months (range 37-84 months). RESULTS: There was no mortality in the donors evaluated...
December 9, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27932137/quality-of-life-according-to-urgency-status-in-de-novo-heart-transplant-recipients
#11
B Díaz-Molina, J L Lambert, F G Vílchez, F Cadenas, M J Bernardo, E Velasco, M Martín, C Morís
INTRODUCTION: Elective heart transplantation (HTX) aims to improve physical ability, increase survival, and improve health-related quality of life (HRQoL) in patients with chronic heart failure. Nevertheless, most patients who undergo urgent HTX are previously healthy, and a transplant could be perceived as a limitation. The aim of this study is to compare HRQoL between elective and urgent heart transplant recipients. METHODS: Cohort study including patients undergoing heart transplantation between January 1998 and March 2012 in a single center...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27926593/cost-effectiveness-of-direct-acting-anti-viral-treatment-in-hepatitis-c-infected-liver-transplant-candidates-with-compensated-cirrhosis-and-hepatocellular-carcinoma
#12
James Salazar, Varun Saxena, James G Kahn, John P Roberts, Neil Mehta, Michael Volk, Jennifer C Lai
BACKGROUND: HCV(+) donors represent an effective strategy to increase liver donor availability to HCV-infected recipients. However, many HCV(+) transplant candidates are now receiving treatment with direct acting anti-virals (DAA) that lower the risk of posttransplant HCV recurrence but could make the patient ineligible for HCV(+) livers. METHODS: We compared pretransplant DAA treatment versus deferred DAA treatment using a cost-effectiveness decision analysis model to estimate incremental cost-effectiveness ratios (ICERs; cost per quality-adjusted life year [QALY] gained) from the societal perspective across a range of HCV(+) liver availability rates...
December 6, 2016: Transplantation
https://www.readbyqxmd.com/read/27917588/the-effect-of-liver-transplantation-on-the-quality-of-life-of-the-recipient-s-main-caregiver-a-systematic-review
#13
REVIEW
Alastair L Young, Ian A Rowe, Kate Absolom, Rebecca L Jones, Amy Downing, Nick Meader, Adam Glaser, Giles J Toogood
Liver transplantation (LT) is a transformative, life-saving procedure with life-long sequale for patients and their caregivers. The impact of LT on the patient's main caregiver can be underestimated. We carried out a systematic review of the impact of LT on the Health-Related Quality of Life (HRQL) of LT patients' main caregivers. We searched 13 medical databases from 1996 to 2015. We included studies with HRQL data on caregivers of patients following LT then quality assessed and narratively synthesized the findings from these studies...
December 5, 2016: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/27897967/an-observational-study-of-donor-ex-vivo-lung-perfusion-in-uk-lung-transplantation-develop-uk
#14
Andrew Fisher, Anders Andreasson, Alexandros Chrysos, Joanne Lally, Chrysovalanto Mamasoula, Catherine Exley, Jennifer Wilkinson, Jessica Qian, Gillian Watson, Oli Lewington, Thomas Chadwick, Elaine McColl, Mark Pearce, Kay Mann, Nicola McMeekin, Luke Vale, Steven Tsui, Nizar Yonan, Andre Simon, Nandor Marczin, Jorge Mascaro, John Dark
BACKGROUND: Many patients awaiting lung transplantation die before a donor organ becomes available. Ex vivo lung perfusion (EVLP) allows initially unusable donor lungs to be assessed and reconditioned for clinical use. OBJECTIVE: The objective of the Donor Ex Vivo Lung Perfusion in UK lung transplantation study was to evaluate the clinical effectiveness and cost-effectiveness of EVLP in increasing UK lung transplant activity. DESIGN: A multicentre, unblinded, non-randomised, non-inferiority observational study to compare transplant outcomes between EVLP-assessed and standard donor lungs...
November 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27862972/long-term-medical-and-psychosocial-outcomes-in-living-liver-donors
#15
REVIEW
M A Dew, Z Butt, A Humar, A F DiMartini
Due to the enduring organ shortage, living donor liver transplantation has been a valuable treatment strategy for advanced liver disease patients for over 20 years. A variety of reviews have summarized the extensive data now available on medical and psychosocial risks to living donors in the aftermath of donation. However, evidence on donor medical and psychosocial outcomes beyond the first year postdonation has not been synthesized in any previous review. The evidence base on such "long-term" outcomes has been growing in recent years...
November 10, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27805505/challenges-for-renal-retransplant-an-overview
#16
Mohamed Adel Bakr, Ahmed Abdelfattah Denewar, Mohamed Hamed Abbas
Despite many achievements in renal transplant in the past few years regarding immunosuppression and tissue matching, the rates of early and late graft loss and return to dialysis are still high. Many of those with primary graft failure will be listed for a kidney retransplant, as this allows for better quality of life than dialysis. Many challenges face those requiring renal retransplant, including first graft nephrectomy and whether site of retransplant should be ipsilateral or contralateral, whether to conduct preemptive retransplant or wait while on dialysis, additional immunologic factors, immunosuppression after retransplant, cancer risk, BK virus infection, and retransplant in pediatrics...
November 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27802832/reproductive-issues-in-patients-undergoing-hematopoietic-stem-cell-transplantation-an-update
#17
REVIEW
Maurizio Guida, Maria Antonietta Castaldi, Rosa Rosamilio, Valentina Giudice, Francesco Orio, Carmine Selleri
In 1963 George Mathé announced to the world that he had cured a patient of leukaemia by means of a bone-marrow transplant. Since than much progress has been made and nowadays Hematopoietic Stem Cell Transplantation (HSCT) is considered the most effective treatment of numerous severe haematological diseases. Gynaecological complications in HSCT women represent a serious concern for these patients, but often underestimated by clinicians in the view of Overall Survival. The main gynaecological complications of HSCT are represented by: premature ovarian failure (POF), thrombocytopenia-associated menorrhagia, genital symptoms or sexual problems in course of chronic GVHD (cGVHD), osteoporosis, secondary solid tumours due to immunosuppressive drugs to treat cGVHD and severity of cGVHD, and fertility and pregnancy issues...
November 1, 2016: Journal of Ovarian Research
https://www.readbyqxmd.com/read/27798034/rationale-and-design-of-platelet-transfusions-in-haematopoietic-stem-cell-transplantation-the-path-pilot-study
#18
Jason Tay, David Allan, Sara Beattie, Christopher Bredeson, Dean Fergusson, Dawn Maze, Mitchell Sabloff, Kednapa Thavorn, Alan Tinmouth
INTRODUCTION: In patients with transient thrombocytopenia being treated with high-dose chemotherapy followed by stem cell rescue-haematopoietic stem cell transplantation (HSCT), prophylactic transfusions are standard therapy to prevent bleeding. However, a recent multicentre trial suggests that prophylactic platelet transfusions in HSCT may not be necessary. Additionally, the potential overuse of platelet products places a burden on a scarce healthcare resource. Moreover, the benefit of prophylactic platelet transfusions to prevent clinically relevant haemorrhage is debatable...
October 24, 2016: BMJ Open
https://www.readbyqxmd.com/read/27788795/physical-symptoms-and-associated-factors-in-chinese-renal-transplant-recipients
#19
H Wei, Z Guan, J Zhao, W Zhang, H Shi, W Wang, J Wang, X Xiao, Y Niu, B Shi
OBJECTIVE: This study aimed to investigate physical symptoms in renal transplant recipients as well as the correlation between self-efficacy and symptom distress. METHODS: A total of 274 consecutive renal transplant recipients were enrolled using a convenience sampling method. The basic characteristics of renal transplant recipients were collected using a general situation questionnaire. Physical symptom distress and self-efficacy were assessed by the Kidney Transplant Questionnaire and the Perceived Health Competence Scale, respectively...
October 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27751935/health-related-quality-of-life-among-older-related-hematopoietic-stem-cell-donors-60-years-is-equivalent-to-that-of-younger-related-donors-18-to-60-years-a-related-donor-safety-study
#20
Galen E Switzer, Jessica Bruce, Deidre M Kiefer, Hati Kobusingye, Rebecca Drexler, RaeAnne M Besser, Dennis L Confer, Mary M Horowitz, Roberta J King, Bronwen E Shaw, Marcie Riches, Brandon Hayes-Lattin, Michael Linenberger, Brian Bolwell, Scott D Rowley, Mark R Litzow, Michael A Pulsipher
The increasing number of older adults with blood-related disorders and the introduction of reduced-intensity conditioning regimens has led to increases in hematopoietic stem cell (HSC) transplantation among older adults and a corresponding increase in the age of siblings who donate HSCs to these patients. Data regarding the donation-related experiences of older donors are lacking. The Related Donor Safety Study aimed to examine/compare health-related quality of life (HRQoL) of older versus younger HSC donors...
January 2017: Biology of Blood and Marrow Transplantation
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