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Surveillance

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https://www.readbyqxmd.com/read/29783049/thermopuncture-for-the-diagnosis-monitoring-and-treatment-of-patients-with-type-2-diabetes
#1
Valery Muzhikov, Elena Vershinina, Ruslan Muzhikov, Kirill Nikitin
BACKGROUND: Type 2 diabetes (T2D) is a socially significant disease that affects millions of patients. There were an estimated 366 million people with this disease in 2011, and, according to the forecast, approximately 552 million will be affected by this disease in 2030. It is well known that the primary diagnosis and treatment of a patient with this disease are quite expensive. What should be done to make it possible for a patient to monitor his own state and provide treatment in his own home using telemedicine? To solve this problem, an alternative concept for the diagnosis, monitoring, and treatment at the basis of traditional Chinese medicine (TCM) combined with mathematical methods of data processing has been used...
May 18, 2018: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29782933/whole-genome-sequencing-and-analyses-identify-high-genetic-heterogeneity-and-diversity-of-rotavirus-genotype-p-6-strains-circulating-in-africa
#2
Martin M Nyaga, Yi Tan, Mapaseka L Seheri, Rebecca A Halpin, Asmik Akopov, Karla M Stucker, Nadia B Fedorova, Susmita Shrivastava, A Duncan Steele, Jason M Mwenda, Brett E Pickett, Suman R Das, M Jeffery Mphahlele
Rotavirus A (RVA) exhibits a wide genotype diversity globally. Little is known about the genetic composition of genotype P[6] from Africa. This study investigated possible evolutionary mechanisms leading to genetic diversity of genotype P[6] VP4 sequences. Phylogenetic analyses on 167 P[6] VP4 full-length sequences were conducted, which included six porcine-origin sequences. Of the 167 sequences, 57 were newly acquired through whole genome sequencing as part of this study. The other 110 sequences were all publicly-available global P[6] VP4 full-length sequences downloaded from GenBank...
May 18, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29782246/precision-medicine-and-radiogenomics-in-breast-cancer-new-approaches-toward-diagnosis-and-treatment
#3
Katja Pinker, Joanne Chin, Amy N Melsaether, Elizabeth A Morris, Linda Moy
Precision medicine is medicine optimized to the genotypic and phenotypic characteristics of an individual and, when present, his or her disease. It has a host of targets, including genes and their transcripts, proteins, and metabolites. Studying precision medicine involves a systems biology approach that integrates mathematical modeling and biology genomics, transcriptomics, proteomics, and metabolomics. Moreover, precision medicine must consider not only the relatively static genetic codes of individuals, but also the dynamic and heterogeneous genetic codes of cancers...
June 2018: Radiology
https://www.readbyqxmd.com/read/29782079/the-dipep-diagnosis-of-pe-in-pregnancy-study-an-observational-study-of-the-diagnostic-accuracy-of-clinical-assessment-d-dimer-and-chest-x-ray-for-suspected-pulmonary-embolism-in-pregnancy-and-postpartum
#4
Steve Goodacre, Kimberley Horspool, Catherine Nelson-Piercy, Marian Knight, Neil Shephard, Fiona Lecky, Steven Thomas, Beverley J Hunt, Gordon Fuller
OBJECTIVE: To identify clinical features associated with PE diagnosis and determine the accuracy of decision rules and D-dimer for diagnosing suspected PE in pregnant/postpartum women. DESIGN: Observational cohort study augmented with additional cases. SETTING: Emergency departments and maternity units at eleven prospectively recruiting sites and maternity units in the United Kingdom Obstetric Surveillance System (UKOSS). POPULATION: 324 pregnant/postpartum women with suspected PE and 198 pregnant/postpartum women with diagnosed PE...
May 21, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29782012/a-microfluidic-platform-for-longitudinal-imaging-in-caenorhabditis-elegans
#5
Kyung Suk Lee, Erel Levine
In the last decade, microfluidic techniques have been applied to study small animals, including the nematode Caenorhabditis elegans, and have proved useful as a convenient live imaging platform providing capabilities for precise control of experimental conditions in real time. In this article, we demonstrate live imaging of individual worms employing WormSpa, a previously-published custom microfluidic device. In the device, multiple worms are individually confined to separate chambers, allowing multiplexed longitudinal surveillance of various biological processes...
May 2, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781981/national-patient-safety-program-in-brazil-incidents-reported-between-2014-and-2017
#6
Tássia Nery Faustino, Edenise Maria Santos da Silva Batalha, Silvana Lima Vieira, Andressa Garcia Nicole, Alexandre Souza Morais, Daisy Maria Rizatto Tronchin, Marta Maria Melleiro
OBJECTIVE: The aim of the study was to analyze the patient safety incidents reported to the Brazilian National Health Surveillance System from March 2014 to March 2017. METHOD: A documentary study that used the records of the incidents published in the Reports of Adverse Events (AE) in Brazil. The following variables were selected: number of incidents by type, type of health service, hospital unit, and degree of harm. To find whether there was a significant difference across the Brazilian regions by notifications related to general incidents, AE, and deaths, the analysis of variance and the Tukey tests were used...
May 16, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29781837/recommendations-on-rectal-surveillance-for-colorectal-cancer-after-subtotal-colectomy-in-patients-with-inflammatory-bowel-disease
#7
Lauranne A A P Derikx, Michiel E de Jong, Frank Hoentjen
Approximately 30% of patients with ulcerative colitis require a colectomy during their disease course. This substantially reduces colorectal cancer risk, although it is still possible to develop colorectal neoplasia in the remaining rectum. Although clear and well-accepted surveillance guidelines exist for patients with inflammatory bowel disease with an intact colon, specific surveillance recommendations following colectomy are less clear. Here, we aim to summarize the prevalence, incidence, and risk factors for developing colorectal cancer in patients with inflammatory bowel disease who underwent subtotal colectomy with a permanent end ileostomy and rectal stump, or with ileorectal anastomosis...
May 17, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29781825/prognostic-value-of-serum-ca19-9-and-perioperative-ca-125-levels-in-ovarian-clear-cell-carcinoma
#8
Jun Zhu, Long Jiang, Hao Wen, Rui Bi, Xiaohua Wu, Xingzhu Ju
BACKGROUND: There are no effective biomarkers for surveillance in ovarian clear cell carcinoma (OCCC), and the value of carbohydrate antigen 125 (CA-125) is limited. We sought to determine the value of both carbohydrate antigen 19-9 (CA19-9) and CA-125 levels postoperatively on the prognosis for OCCC. METHODS: A total of 130 patients with OCCC who were consecutively treated by cytoreduction at Fudan University Shanghai Cancer Center were reviewed retrospectively...
May 18, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29781569/pediatric-superior-vena-cava-syndrome-an-evidence-based-systematic-review-of-the-literature
#9
REVIEW
Fadi Nossair, Peter Schoettler, Joanne Starr, Anthony K C Chan, Ivan Kirov, Bosco Paes, Arash Mahajerin
Superior vena cava syndrome (SVCS) results in vascular, respiratory, and neurologic compromise. A systematic search was conducted to determine the prevalence of pediatric SVCS subtypes and identify clinical characteristics/treatment strategies that may influence overall outcomes. Data from 101 case reports/case series (142 patients) were analyzed. Morbidity (30%), mortality (18%), and acute complications (55%) were assessed as outcomes. Thrombosis was present in 36%, with multi-modal anticoagulation showing improved outcome by >50% (P = 0...
May 21, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29781424/review-analysis-and-impact-of-co-circulating-h5n1-and-h9n2-avian-influenza-viruses-in-bangladesh
#10
Rokshana Parvin, Jahan Ara Begum, Mohammed Nooruzzaman, Emdadul Haque Chowdhury, Mohammad Rafiqul Islam, Thomas W Vahlenkamp
Almost the full range of 16 haemagglutinin (HA) and nine neuraminidase subtypes of avian influenza viruses (AIVs) has been detected either in waterfowl, land-based poultry or in the environment in Bangladesh. AIV infections in Bangladesh affected a wide range of host species of terrestrial poultry. The highly pathogenic avian influenza (AI) H5N1 and low pathogenic AI H9N2 were found to co-circulate and be well entrenched in the poultry population, which has caused serious damage to the poultry industry since 2007...
May 21, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29781213/thyroid-microcalcifications-in-the-absence-of-identifiable-nodules-and-their-association-with-thyroid-cancer
#11
Carolina Whittle, Marisol García, Eleonora Horvath, Jeannie Slater, Carmen Carrasco
OBJECTIVES: To determine ultrasound (US) and clinical findings of thyroid microcalcifications in the absence of a nodule and their association with the risk of malignancy. METHODS: The Institutional Review Board approved a 5-year retrospective study. Twenty-one patients with clustered or scattered thyroid microcalcifications in the absence of nodules on US images who underwent fine-needle aspiration biopsies (FNABs) were included. Demographic and clinical data, US findings, and pathologic results were registered...
May 21, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29781203/the-long-non-coding-rna-transcriptome-landscape-in-cho-cells-under-batch-and-fed-batch-conditions
#12
Davide Vito, C Mark Smales
The role of non-coding RNAs in determining growth, productivity and recombinant product quality attributes in Chinese hamster ovary (CHO) cells has received much attention in recent years, exemplified by studies into microRNAs in particular. However, other classes of non-coding RNAs have received less attention. One such class are the non-coding RNAs known collectively as long non-coding RNAs (lncRNAs). We have undertaken the first landscape analysis of the lncRNA transcriptome in CHO using a mouse based microarray that also provided for the surveillance of the coding transcriptome...
May 21, 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29781162/predictors-of-ultrasound-failure-to-detect-hepatocellular-carcinoma
#13
Mariya L Samoylova, Neil Mehta, John P Roberts, Francis Y Yao
Current guidelines recommend ultrasound (US) for hepatocellular carcinoma (HCC) surveillance in cirrhosis. We assess predictors of decreased US sensitivity for detecting HCC. At a single U.S. center, all HCC patients evaluated for liver transplant (LT) receive an abdominal US. In consecutive patients presenting 2007-2015, untreated lesions found on CT/MRI within 3 months of US were compared with US findings. Multivariable logistic regression models compared US sensitivities by patient characteristics. Of 1008 patients completing LT evaluation, 47...
May 21, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29780850/canada-wide-epidemic-of-emm74-group-a-streptococcus-invasive-disease
#14
Sarah Teatero, Allison McGeer, Gregory J Tyrrell, Linda Hoang, Hanan Smadi, Marc-Christian Domingo, Paul N Levett, Michael Finkelstein, Ken Dewar, Agron Plevneshi, Taryn B T Athey, Jonathan B Gubbay, Michael R Mulvey, Irene Martin, Walter Demczuk, Nahuel Fittipaldi
Background: The number of invasive group A Streptococcus (iGAS) infections due to hitherto extremely rare type emm74 strains has increased in several Canadian provinces since late 2015. We hypothesized that the cases recorded in the different provinces are linked and caused by strains of an emm74 clone that recently emerged and expanded explosively. Methods: We analyzed both active and passive surveillance data for iGAS infections and used whole-genome sequencing to investigate the phylogenetic relationships of the emm74 strains responsible for these invasive infections country-wide...
May 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29780846/epidemiology-of-hip-and-groin-injuries-in-collegiate-athletes-in-the-united-states
#15
Yehuda E Kerbel, Christopher M Smith, John P Prodromo, Michael I Nzeogu, Mary K Mulcahey
Background: Hip and groin pain is a common complaint among athletes. Few studies have examined the epidemiology of hip and groin injuries in collegiate athletes across multiple sports. Purpose: To describe the rates, mechanisms, sex-based differences, and severity of hip/groin injuries across 25 collegiate sports. Study Design: Descriptive epidemiology study. Methods: Data from the 2009-2010 through 2013-2014 academic years were obtained from the National Collegiate Athletic Association Injury Surveillance Program (NCAA ISP)...
May 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29780775/optimal-cutoff-level-of-serum-squamous-cell-carcinoma-antigen-to-detect-recurrent-cervical-squamous-cell-carcinoma-during-post-treatment-surveillance
#16
Jinju Oh, Jin Young Bae
Objective: The objective of this study was to determine the optimal cutoff level of serum squamous cell carcinoma antigen (SCC-Ag) to detect recurrent cervical squamous cell carcinoma during post-treatment surveillance. Methods: Between January 2000 and July 2014, a total of 158 women with cervical squamous cell carcinoma were treated with radiotherapy with or without concurrent chemotherapy at our department. A total of 1,550 serum SCC-Ag tests performed during post-treatment surveillance of the 158 patients were included in this retrospective study...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29780766/racial-ethnic-differences-in-health-insurance-adequacy-and-consistency-among-children-evidence-from-the-2011-12-national-survey-of-children-s-health
#17
Tulay G Soylu, Eman Elashkar, Fatemah Aloudah, Munir Ahmed, Panagiota Kitsantas
Background: Surveillance of disparities in healthcare insurance, services and quality of care among children are critical for properly serving the medical/healthcare needs of underserved populations. The purpose of this study was to assess racial/ethnic differences in children's (0 to 17 years old) health insurance adequacy and consistency (child has insurance coverage for the last 12 months). Design and methods: We used data from the 2011/2012 National Survey of Children's Health (n=79,474)...
February 5, 2018: Journal of Public Health Research
https://www.readbyqxmd.com/read/29780765/alcohol-brand-use-of-youth-appealing-advertising-and-consumption-by-youth-and-adults
#18
Alisa A Padon, Rajiv N Rimal, Michael Siegel, William DeJong, Timothy S Naimi, David H JernFigan
Background: Youth exposure to alcohol marketing has been shown to be an important contributor to the problem of underage drinking in the U.S. More work is needed on identifying and minimizing content with particular appeal to youth. Design and Methods: We tested the association between the youth-appeal of marketing content of televised alcohol advertisements and the brand-specific alcohol consumption of both underage youth and adults. We used existing data from three sources: a brand-specific alcohol consumption survey among underage youth ( N =1032), a brand-specific alcohol consumption survey among adults ( N ~13,000), and an analysis of content appealing to youth (CAY) in a sample of televised alcohol advertisements ( n =96) aired during the youth survey...
February 5, 2018: Journal of Public Health Research
https://www.readbyqxmd.com/read/29780721/type-b-aortic-dissection-new-perspectives
#19
REVIEW
Marc A A M Schepens
Background: Stanford type B aortic dissection is one of the aortic catastrophes with a high mortality and morbidity that needs immediate or delayed treatment, either surgically or endovascularly. This comprehensive review article addresses the current status of open, endovascular and hybrid treatment options for type B aortic dissections with the focus on new therapeutic perspectives. Methods: Evaluation of currently available evidence based on randomized and registry data and personal experience...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29780595/early-detection-of-ulcerative-colitis-associated-colorectal-cancer
#20
REVIEW
Yu Zhen, Chengxin Luo, Hu Zhang
Colitis-associated colorectal cancer (CACC) is one of the most serious complications of inflammatory bowel disease (IBD), particularly in ulcerative colitis (UC); it accounts for approximately 15% of all-causes mortality among IBD patients. Because CACC shows a worse prognosis and higher mortality than sporadic colorectal cancer, early detection is critical. Colonoscopy is primarily recommended for surveillance and several advanced endoscopic imaging techniques are emerging. In addition, recent studies have reported on attempts to develop clinically relevant biomarkers for surveillance using various biosamples, which may become high-performance screening tools in the future, so the best approach and technique for cancer surveillance in long-standing UC patients remain under debate...
May 2018: Gastroenterology Report
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