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https://www.readbyqxmd.com/read/28957736/gene-expression-of-selenoproteins-can-be-regulated-by-thioredoxin-txn-silence-in-chicken-cardiomyocytes
#1
Jie Yang, Sattar Hamid, Qi Liu, Jingzeng Cai, Shiwen Xu, Ziwei Zhang
Thioredoxin (Txn) system is the most crucial antioxidant defense mechanism in myocardium. The aim of this study was to clarify the effect of Txn low expression on 25 selenoproteins in chicken cardiomyocytes. We developed a Se-deficient model (0.033mg/kg) and Txn knock down cardiomyocytes model (siRNA) studies. Western Blot, Quantitative Real-time PCR (qPCR) were performed, and correlation analysis, heat map were used for further analysis. Both low expression of Txn models are significantly decreased (P<0...
September 4, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28951709/fabrication-of-tamarindus-indica-seeds-extract-loaded-cream-for-photo-aged-skin-visioscan-%C3%A2-studies
#2
Muhammad Khurram Waqas, Barkat Ali Khan, Naveed Akhtar, Farzana Chowdhry, Haroon Khan, Sattar Bakhsh, Shahzeb Khan, Akhtar Rasul
INTRODUCTION: Intracellular and extracellular oxidative stress triggered by free radicals promotes skin aging, which is designated by atypical pigmentation and wrinkles. The consumption of antioxidants is an efficacious measure to avert symptoms involved in skin aging. AIM: The current research was commenced to explore the anti-aging potential of antioxidants present in Tamarindus indica seeds extract. MATERIAL AND METHODS: Tamarindus indica seeds extract was obtained by concentrating the ethanolic extract of seeds...
August 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28940925/evaporation-directed-crack-patterning-of-metal-organic-framework-colloidal-films-and-their-application-as-photonic-sensors
#3
Olivier Dalstein, Effrosyni Gkaniatsou, Clemence Sicard, Ozlem Sel, Hubert Perrot, Christian Serre, Cedric Boissiere, Marco Faustini
Herein, a straightforward crack-patterning method is reported allowing the direct formation of periodic cracks in Metal-Organic Framework nanoparticles films during dip-coating deposition. The crack propagation and periodicity can be easily tailored by controlling the evaporation front and the withdrawal speed. Several MOF patterned films can be fabricated on large surfaces and on several substrates (flat, curved or flexible) including the inner surface of a tube, not achievable by other lithographic techniques...
September 22, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28922735/assessing-the-interplay-of-childhood-adversities-with-more-recent-stressful-life-events-and-conditions-in-predicting-panic-pathology-among-adults-from-the-general-population
#4
E Asselmann, J Stender, H J Grabe, J König, C O Schmidt, A O Hamm, C A Pané-Farré
BACKGROUND: Although research suggests that (a) childhood adversities and more recent stressful life events/conditions are risk factors for panic pathology and that (b) early life stress increases vulnerability to later psychopathology, it remains unclear whether childhood adversities amplify the association between more recent stressful life events/conditions and panic pathology. METHODS: Data were derived from a general population sample (Study of Health in Pomerania, SHIP)...
January 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28901441/profiling-of-differentially-expressed-genes-in-adipose-tissues-of-multiple-symmetric-lipomatosis
#5
Ke Chen, Linghao Wang, Wenjun Yang, Changfa Wang, Gui Hu, Zhaohui Mo
Multiple symmetric lipomatosis (MSL) is a rare disorder characterized by aberrant multiple and symmetric subcutaneous adipose tissue accumulation in the face, neck, shoulders, back, chest and abdomen, severely affecting the quality of life of patients. At present, precise MSL etiology and pathogenesis remain to be elucidated. The present study first utilized a digital gene expression technique with a next‑generation sequencing platform to profile differentially expressed genes in three cases of MSL vs. normal control tissue...
September 7, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28892238/low-temperature-reductive-aminolysis-of-carbohydrates-to-diamines-and-aminoalcohols-through-heterogeneous-catalysis
#6
Michiel Pelckmans, Walter Vermandel, Frederik Van Waes, Kristof Moonen, Bert F Sels
Short amines such as ethanolamines and ethylene diamines are important compounds in today's bulk and fine chemicals industry. Unfortunately, current industrial manufacture of these chemicals relies on fossil resources and requires severe safety management to handle the explosive or toxic intermediates. Inspired by the elegant working mechanism of Aldolase enzymes, a novel heterogeneously catalyzed process, viz. reductive aminolysis, was developed for the efficient production of short amines from carbohydrates at low temperature...
September 11, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28872766/ht-supersage-of-the-gut-tissue-of-a-vip3aa-resistant-heliothis-virescens-lepidoptera-noctuidae-strain-provides-insights-into-the-basis-of-resistance
#7
Camilo Ayra-Pardo, Maria E Ochagavía, Ben Raymond, Asim Gulzar, Lianet Rodríguez-Cabrera, Claudia Rodríguez de la Noval, Ivis Morán Bertot, Ryohei Terauchi, Kentaro Yoshida, Hideo Matsumura, Pilar Téllez Rodríguez, Daily Hernández Hernández, Orlando Borrás-Hidalgo, Denis J Wright
Multi-toxin Bt-crops expressing insecticidal toxins with different modes of action e.g. Cry and Vip, are expected to improve resistance management in target pests. While Cry1A resistance has been relatively well characterized in some insect species, this is not the case for Vip3A, for which no mechanism of resistance has yet been identified. Here we applied HT-SuperSAGE to analyze the transcriptome of the gut tissue of tobacco budworm Heliothis virescens (F.) laboratory-selected for Vip3Aa resistance. From a total of 1 324 252 sequence reads, 58951 26-bp tags were obtained representing 17 751 non-singleton unique transcripts (UniTags) from genetically similar Vip3Aa-resistant (Vip-Sel) and susceptible control (Vip-Unsel) strains...
September 5, 2017: Insect Science
https://www.readbyqxmd.com/read/28858930/orifice-preserving-double-opposing-z-plasty-for-partial-split-ear-lobe-repair-a-review-of-25-cases
#8
Harish K Sharma, Deepti Gupta, Shalu Punj
BACKGROUND: Surgeons often come across split earlobe (SEL) deformities in their clinical practice which usually result from wearing heavy earrings for a long duration. It is of utmost importance to achieve a satisfactory repair with increased strength in one go. OBJECTIVE: To describe a strong repair for partial SEL with preservation of the orifice. MATERIALS AND METHODS: This study is a retrospective review of 25 patients (36 earlobes), who underwent repair of partial SEL deformity with an orifice preserving double opposing Z-plasty in the hospital, from January 2014 to June 2015...
August 29, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28858184/idiopathic-spinal-epidural-fat-accumulation-is-associated-with-hyperlipidemia
#9
Shinichi Ishihara, Nobuyuki Fujita, Mitsuru Yagi, Takashi Tsuji, Takehiro Michikawa, Yuji Nishiwaki, Yasuyuki Fukui, Keisuke Horiuchi, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
STUDY DESIGN: Single-center retrospective analysis of consecutively collected data. OBJECTIVES: To determine the clinical characteristics of idiopathic spinal epidural lipomatosis (SEL). SUMMARY OF BACKGROUND DATA: SEL is associated with the overt accumulation of nonencapsulated adipose tissue in the epidural space, leading to spinal cord or nerve root compression. The etiology of this condition is currently not completely understood. METHODS: Data of 166 male patients who underwent primary surgery for lumbar spinal canal stenosis (LSS) from May 2013 to February 2016 were retrospectively reviewed...
August 29, 2017: Spine
https://www.readbyqxmd.com/read/28836775/identification-of-%C3%AE-fe-in-high-silica-zeolites-on-the-basis-of-ab-initio-electronic-structure-calculations
#10
Simon D Hallaert, Max L Bols, Pieter Vanelderen, Robert A Schoonheydt, Bert F Sels, Kristine Pierloot
α-Fe is the precursor of the reactive Fe(IV)═O core responsible for methane oxidation in Fe-containing zeolites. To get more insight into the nature and stability of α-Fe in different zeolites, the binding of Fe(II) at six-membered-ring cation exchange sites (6MR) in ZSM-5, zeolite beta, and ferrierite was investigated using DFT and multireference ab initio methods (CASSCF/CASPT2). CASPT2 ligand field (LF) excitation energies of all sites were compared with the experimental DR-UV-vis spectra reported by Snyder et al...
August 24, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28836514/ectopic-pancreas-in-the-upper-gastrointestinal-tract-is-endosonographic-diagnosis-reliable-data-from-the-german-endoscopic-ultrasound-registry-and-review-of-the-literature
#11
Uwe Gottschalk, Christoph F Dietrich, Christian Jenssen
BACKGROUND: Ectopic pancreas (EP) belongs to the most frequent subepithelial lesions (SELs) of the upper gastrointestinal (GI) tract. In the majority of cases, it is detected incidentally. Differential diagnosis from mesenchymal subepithelial tumors may be difficult. METHODS: Among 24,308 endosonographic examinations and interventions, which were prospectively enrolled in the database of the German Endoscopic Ultrasound (EUS) Registry from January 2009 to August 2013, 575 were performed for suspected SELs of the upper GI tract...
August 24, 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28830376/hydrophilic-intraocular-lens-opacification-after-posterior-lamellar-keratoplasty-a-material-analysis-with-special-reference-to-optical-quality-assessment
#12
Bert C Giers, Tamer Tandogan, Gerd U Auffarth, Chul Y Choi, Florian N Auerbach, Saadettin Sel, Christian Mayer, Ramin Khoramnia
BACKGROUND: Laboratory analysis and optical quality assessment of explanted hydrophilic intraocular lenses (IOLs) with clinically significant opacification after posterior lamellar keratoplasty (DMEK and DSAEK). METHODS: Thirteen opacified IOLs after posterior lamellar keratoplasty, 8 after descemet stripping automated endothelial keratoplasty (DSAEK), 3 after descemet membrane endothelial keratoplasty (DMEK) and 2 after both DSAEK and DMEK were analysed in our laboratory...
August 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28820764/severe-case-of-renal-coloboma-syndrome-in-long-term-follow-up
#13
Lise Sels, Werner Dirven, Koenraad Devriendt, Anita Leys
PURPOSE: To characterize the ocular features of a severe case of renal coloboma syndrome in a long-term follow-up. METHODS: Observational case report over a period of 45 years. Examination under anesthesia at the age of 3 months, repeated ophthalmologic examination (age 7, 14, 25, 45 years), fluorescein and indocyanine green angiography, electroretinography, ocular ultrasound, optical coherence tomography, computed tomography scan orbits, and magnetic resonance imaging of the brain...
August 17, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28814089/antioxidant-therapy-impresses-in-oxidative-stress-induced-kidney-cells
#14
M Alpay, G Kismali, O Meral, T Sel, R Ozmerdivenli, O Pasin
INTRODUCTION:   Renal cell cancer (RCC) is not a single entity, but consists of different types of tumors derived from various parts of the nephron (epithelium or renal tubules). It is known that cancer initiation and progression is related to the balance between oxidants and antioxidants directly. Interestingly, advanced stages of cancer such as metastasis, angiogenesis are associated with cell oxidative capacity. Familiar antioxidative substances such as carotenes and vitamin C inhibit oxidation of other molecules during carcinogenesis...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28812151/high-clinical-impact-and-diagnostic-accuracy-of-eus-guided-biopsy-sampling-of-subepithelial-lesions-a-prospective-comparative-study
#15
Per Hedenström, Hanns-Ulrich Marschall, Bengt Nilsson, Akif Demir, Björn Lindkvist, Ola Nilsson, Riadh Sadik
BACKGROUND: In a tertiary center setting we aimed to study the diagnostic accuracy and clinical impact of EUS-guided biopsy sampling (EUS-FNB) with a reverse bevel needle compared with that of fine needle aspiration (EUS-FNA) in the work-up of subepithelial lesions (SEL). METHODS: All patients presenting with SELs referred for EUS-guided sampling were prospectively included in 2012-2015. After randomization of the first pass modality, dual sampling with both EUS-FNB and EUS-FNA was performed in each lesion...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28783319/sharper-reaction-monitoring-generation-of-a-narrow-linewidth-nmr-singlet-without-x-pulses-in-an-inhomogeneous-magnetic-field
#16
Ariana B Jones, Guy C Lloyd-Jones, Dušan Uhrín
We report a new pure-shift method, termed SHARPER (Sensitive, Homogeneous, And Resolved PEaks in Real time) designed for the analysis of reactions and equilibria by NMR. By focusing on a single selected signal, SHARPER removes all heteronuclear couplings of a selected nucleus without the need to pulse on X channels, thus overcoming hardware limitations of conventional spectrometers. A more versatile decoupling scheme, termed sel-SHARPER, removes all heteronuclear and homonuclear couplings of the selected signal...
September 19, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28782002/comparison-of-submucosal-tunneling-biopsy-versus-eus-guided-fna-for-gastric-subepithelial-lesions-a-prospective-study-with-crossover-design
#17
Hideki Kobara, Hirohito Mori, Naoki Nishimoto, Shintaro Fujihara, Noriko Nishiyama, Maki Ayaki, Tatsuo Yachida, Tae Matsunaga, Taiga Chiyo, Nobuya Kobayashi, Koji Fujita, Kiyohito Kato, Hideki Kamada, Makoto Oryu, Kunihiko Tsutsui, Hisakazu Iwama, Reiji Haba, Tsutomu Masaki
BACKGROUND AND STUDY AIMS : Endoscopic ultrasound-guided fine needle aspiration (FNA) for gastrointestinal subepithelial lesions (SELs) has limited diagnostic accuracy due to technical problems and small lesion size. We previously reported a novel submucosal tunneling biopsy (STB) technique for sampling SELs. This study aimed to evaluate the diagnostic ability and safety of STB compared to that of FNA for SELs. PATIENTS AND METHODS : The study was a non-randomized, prospective comparative study with crossover design in patients with endoluminal gastric SELs...
August 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28777321/prevalence-and-genetic-characteristics-of-staphylococcus-aureus-and-staphylococcus-argenteus-isolates-harboring-panton-valentine-leukocidin-enterotoxins-and-tsst-1-genes-from-food-handlers-in-myanmar
#18
Meiji Soe Aung, Thida San, Mya Mya Aye, San Mya, Win Win Maw, Khin Nyein Zan, Wut Hmone Win Htut, Mitsuyo Kawaguchiya, Noriko Urushibara, Nobumichi Kobayashi
Asymptomatic carriers of toxigenic Staphylococcus aureus are potential source of diseases, including food poisoning. Toxigenic potential and genetic traits of colonizing S. aureus were investigated for 563 healthy food handlers in Myanmar. Carriage of S. aureus was found in 110 individuals (19.5%), and a total of 144 S. aureus isolates were recovered from nasal cavities (110 isolates) and hands (34 isolates). Panton-Valentine leucocidin genes (pvl) were detected in 18 isolates (12.5%), among which 11 isolates were classified into coa-VIa, agr type III, and ST1930 (CC96) that had been also detected in pvl-positive clinical isolates in Myanmar...
August 4, 2017: Toxins
https://www.readbyqxmd.com/read/28735963/selenium-accelerates-chicken-dendritic-cells-differentiation-and-affects-selenoproteins-expression
#19
Zhepeng Sun, Ci Liu, Tingru Pan, Haidong Yao, Shu Li
Selenium (Se) promotes immune cell differentiation and improves immune response. Antigen-presenting cells such as dendritic cells (DCs) play an important role in immune system, however, the impact of Se on DCs is still unclear. In this study, we successfully induced and cultured chicken DCs from peripheral blood mononuclear cells by incubating mononuclear cells with 50 ng/mL recombinant chicken granulocyte-macrophage colony stimulating factor and 10 ng/mL recombinant chicken interleukin-4 for total 9 days...
July 21, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28733452/chronic-hypertension-increases-aortic-endothelial-hydraulic-conductivity-by-upregulating-endothelial-aquaporin-1-expres-sion
#20
Jimmy Deon Toussaint, Chirag Bharavi Raval, Tieuvi Nguyen, Hadi Fadaifard, Shripad Joshi, George Wolberg, Steven Quarfordt, Kung-Ming Jan, David S Rumschitzki
Numerous studies examine aquaporins' role in osmotic water transport in various systems but virtually none focus on aquaporins' role in hydrostatically-driven water transport involving mammalian cells save for our laboratory's recent study of aortic endothelial cells. Here we inves-tigate aquaporin-1 expression and function in the aortic endothelium in two high-renin rat mod-els of hypertension, the spontaneously hypertensive genetically altered Wystar-Kyoto rat variant and Sprague-Dawley rats made hypertensive by two kidney, one clip Goldblatt surgery...
July 21, 2017: American Journal of Physiology. Heart and Circulatory Physiology
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