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https://www.readbyqxmd.com/read/28820764/severe-case-of-renal-coloboma-syndrome-in-long-term-follow-up
#1
Lise Sels, Werner Dirven, Koenraad Devriendt, Anita Leys
PURPOSE: To characterize the ocular features of a severe case of renal coloboma syndrome in a long-term follow-up. METHODS: Observational case report over a period of 45 years. Examination under anesthesia at the age of 3 months, repeated ophthalmologic examination (age 7, 14, 25, 45 years), fluorescein and indocyanine green angiography, electroretinography, ocular ultrasound, optical coherence tomography, computed tomography scan orbits, and magnetic resonance imaging of the brain...
August 17, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28814089/antioxidant-therapy-impresses-in-oxidative-stress-induced-kidney-cells
#2
M Alpay, G Kismali, O Meral, T Sel, R Ozmerdivenli, O Pasin
INTRODUCTION:   Renal cell cancer (RCC) is not a single entity, but consists of different types of tumors derived from various parts of the nephron (epithelium or renal tubules). It is known that cancer initiation and progression is related to the balance between oxidants and antioxidants directly. Interestingly, advanced stages of cancer such as metastasis, angiogenesis are associated with cell oxidative capacity. Familiar antioxidative substances such as carotenes and vitamin C inhibit oxidation of other molecules during carcinogenesis...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28812151/high-clinical-impact-and-diagnostic-accuracy-of-eus-guided-biopsy-sampling-of-subepithelial-lesions-a-prospective-comparative-study
#3
Per Hedenström, Hanns-Ulrich Marschall, Bengt Nilsson, Akif Demir, Björn Lindkvist, Ola Nilsson, Riadh Sadik
BACKGROUND: In a tertiary center setting we aimed to study the diagnostic accuracy and clinical impact of EUS-guided biopsy sampling (EUS-FNB) with a reverse bevel needle compared with that of fine needle aspiration (EUS-FNA) in the work-up of subepithelial lesions (SEL). METHODS: All patients presenting with SELs referred for EUS-guided sampling were prospectively included in 2012-2015. After randomization of the first pass modality, dual sampling with both EUS-FNB and EUS-FNA was performed in each lesion...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28783319/sharper-reaction-monitoring-generation-of-a-narrow-line-width-nmr-singlet-without-x-pulses-in-an-inhomogeneous-magnetic-field
#4
Ariana B Jones, Guy C Lloyd-Jones, Dusan Uhrin
We report a new 'pure-shift' method, termed 'SHARPER' (Sensitive, Homogeneous And Resolved PEaks in Real time) de-signed for the analysis of reactions and equilibria by NMR. By focusing on a single selected signal, SHARPER removes all heteronuclear couplings of a selected nucleus without the need to pulse on X channels, thus overcoming hardware limitations of conventional spectrometers. A more versatile decoupling scheme, termed 'sel-SHARPER', removes all heteronuclear and homonuclear couplings of the selected signal...
August 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28782002/comparison-of-submucosal-tunneling-biopsy-versus-eus-guided-fna-for-gastric-subepithelial-lesions-a-prospective-study-with-crossover-design
#5
Hideki Kobara, Hirohito Mori, Naoki Nishimoto, Shintaro Fujihara, Noriko Nishiyama, Maki Ayaki, Tatsuo Yachida, Tae Matsunaga, Taiga Chiyo, Nobuya Kobayashi, Koji Fujita, Kiyohito Kato, Hideki Kamada, Makoto Oryu, Kunihiko Tsutsui, Hisakazu Iwama, Reiji Haba, Tsutomu Masaki
BACKGROUND AND STUDY AIMS : Endoscopic ultrasound-guided fine needle aspiration (FNA) for gastrointestinal subepithelial lesions (SELs) has limited diagnostic accuracy due to technical problems and small lesion size. We previously reported a novel submucosal tunneling biopsy (STB) technique for sampling SELs. This study aimed to evaluate the diagnostic ability and safety of STB compared to that of FNA for SELs. PATIENTS AND METHODS : The study was a non-randomized, prospective comparative study with crossover design in patients with endoluminal gastric SELs...
August 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28777321/prevalence-and-genetic-characteristics-of-staphylococcus-aureus-and-staphylococcus-argenteus-isolates-harboring-panton-valentine-leukocidin-enterotoxins-and-tsst-1-genes-from-food-handlers-in-myanmar
#6
Meiji Soe Aung, Thida San, Mya Mya Aye, San Mya, Win Win Maw, Khin Nyein Zan, Wut Hmone Win Htut, Mitsuyo Kawaguchiya, Noriko Urushibara, Nobumichi Kobayashi
Asymptomatic carriers of toxigenic Staphylococcus aureus are potential source of diseases, including food poisoning. Toxigenic potential and genetic traits of colonizing S. aureus were investigated for 563 healthy food handlers in Myanmar. Carriage of S. aureus was found in 110 individuals (19.5%), and a total of 144 S. aureus isolates were recovered from nasal cavities (110 isolates) and hands (34 isolates). Panton-Valentine leucocidin genes (pvl) were detected in 18 isolates (12.5%), among which 11 isolates were classified into coa-VIa, agr type III, and ST1930 (CC96) that had been also detected in pvl-positive clinical isolates in Myanmar...
August 4, 2017: Toxins
https://www.readbyqxmd.com/read/28735963/selenium-accelerates-chicken-dendritic-cells-differentiation-and-affects-selenoproteins-expression
#7
Zhepeng Sun, Ci Liu, Tingru Pan, Haidong Yao, Shu Li
Selenium (Se) promotes immune cell differentiation and improves immune response. Antigen-presenting cells such as dendritic cells (DCs) play an important role in immune system, however, the impact of Se on DCs is still unclear. In this study, we successfully induced and cultured chicken DCs from peripheral blood mononuclear cells by incubating mononuclear cells with 50 ng/mL recombinant chicken granulocyte-macrophage colony stimulating factor and 10 ng/mL recombinant chicken interleukin-4 for total 9 days...
July 21, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28733452/chronic-hypertension-increases-aortic-endothelial-hydraulic-conductivity-by-upregulating-endothelial-aquaporin-1-expres-sion
#8
Jimmy Deon Toussaint, Chirag Bharavi Raval, Tieuvi Nguyen, Hadi Fadaifard, Shripad Joshi, George Wolberg, Steven Quarfordt, Kung-Ming Jan, David S Rumschitzki
Numerous studies examine aquaporins' role in osmotic water transport in various systems but virtually none focus on aquaporins' role in hydrostatically-driven water transport involving mammalian cells save for our laboratory's recent study of aortic endothelial cells. Here we inves-tigate aquaporin-1 expression and function in the aortic endothelium in two high-renin rat mod-els of hypertension, the spontaneously hypertensive genetically altered Wystar-Kyoto rat variant and Sprague-Dawley rats made hypertensive by two kidney, one clip Goldblatt surgery...
July 21, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28715690/a-dft-study-on-surface-enhanced-raman-spectroscopy-of-aromatic-dithiol-derivatives-adsorbed-on-gold-nanojunctions
#9
Tingting You, Xiufeng Lang, Anping Huang, Penggang Yin
A computational study on aromatic dithiol derivatives (HS-Ar-X-Ar-SH, X=O, S, Se, NH, CH2, NN, CHCH, CC) interacting with gold cluster(s) was presented to investigate the chemical enhancement mechanism related to surface-enhanced Raman spectroscopy (SERS) for molecular junctions. Density functional theory (DFT) were performed on derivatives molecules as well as their single-end-linked (SEL) or double-end-linked (DEL) complexes for geometric, spectra, electronic and excitation properties, leading to discussions on dominant factor during SERS process...
July 12, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28714887/characterization-of-enterotoxigenic-bacillus-cereus-sensu-lato-and-staphylococcus-aureus-isolates-and-associated-enterotoxin-production-dynamics-in-milk-or-meat-based-broth
#10
Laura Walker-York-Moore, Sean C Moore, Edward M Fox
Bacillus cereus sensu lato species, as well as Staphylococcus aureus, are important pathogenic bacteria which can cause foodborne illness through the production of enterotoxins. This study characterised enterotoxin genes of these species and examined growth and enterotoxin production dynamics of isolates when grown in milk or meat-based broth. All B. cereus s. l. isolates harboured nheA, hblA and entFM toxin genes, with lower prevalence of bceT and hlyII. When grown at 16 °C, toxin production by individual B...
July 15, 2017: Toxins
https://www.readbyqxmd.com/read/28710985/spinal-cord-compression-secondary-to-idiopathic-thoracic-epidural-lipomatosis-in-an-adolescent-a-case-report-and-review-of-literature
#11
Rumaiza Al-Yafeai, Yazid Maghrabi, Hussein Malibary, Saleh Baeesa
INTRODUCTION: Spinal epidural lipomatosis (SEL) is a rare condition that presents with progressive spinal cord or nerve root compression. It is commonly reported in patients receiving long-term exogenous steroid therapy or in patients with endogenous steroid overproduction. The occurrence of this condition as an idiopathic entity is rarely reported. CASE PRESENTATION: The authors present the clinical course and outcome of a 16-year-old male student, who presented with progressive spastic paraparesis of a one-year duration caused by idiopathic spinal epidural lipomatosis...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28691130/young-and-advanced-tumor-some-2d-electrodynamic-distinctions-melanoma-and-satellite-during-a-vascular-occlusion-test-feasibility-study
#12
Y Babich, M Nuzhdina, S Syniuta
Conventional methods of electrobioimpedance imaging are not suited for adequate visualization of the skin electrical impedance landscape (SEL) because they do not provide high spatial resolution at large enough area of view. The skin electrodynamics introscopy (SEI) enabled dynamic spectral imaging of the SEL at 32 × 64 mm(2) area with 1 mm spatial resolution. The focus of the study was to investigate the SEL distinguishing features between early and advanced-stage cancer at the model object of melanoma and its satellite...
July 10, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28685826/promoting-positive-youth-development-through-school-based-social-and-emotional-learning-interventions-a-meta-analysis-of-follow-up-effects
#13
Rebecca D Taylor, Eva Oberle, Joseph A Durlak, Roger P Weissberg
This meta-analysis reviewed 82 school-based, universal social and emotional learning (SEL) interventions involving 97,406 kindergarten to high school students (Mage  = 11.09 years; mean percent low socioeconomic status = 41.1; mean percent students of color = 45.9). Thirty-eight interventions took place outside the United States. Follow-up outcomes (collected 6 months to 18 years postintervention) demonstrate SEL's enhancement of positive youth development. Participants fared significantly better than controls in social-emotional skills, attitudes, and indicators of well-being...
July 2017: Child Development
https://www.readbyqxmd.com/read/28680005/efficacy-of-endoscopic-ultrasound-guided-fine-needle-aspiration-for-schwannoma-six-cases-of-a-retrospective-study
#14
Mika Takasumi, Takuto Hikichi, Tadayuki Takagi, Rei Suzuki, Ko Watanabe, Jun Nakamura, Mitsuru Sugimoto, Hitomi Kikuchi, Naoki Konno, Yuichi Waragai, Hiroyuki Asama, Katsutoshi Obara, Hiromasa Ohira
BACKGROUND: Schwannomas are difficult to diagnose using imaging alone. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is an effective and safe tissue sampling technique. Nevertheless, few reports have described EUS-FNA for schwannoma. OBJECTIVE: This study evaluates the efficacy of EUS-FNA for diagnosing schwannoma. METHODS: This retrospective study examined six consecutive schwannoma patients who were diagnosed as having schwannoma either from EUS-FNA results or from surgically resected specimens...
July 5, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28650663/overexpression-and-low-expression-of-selenoprotein-s-impact-ochratoxin-a-induced-porcine-cytotoxicity-and-apoptosis-in-vitro
#15
Fang Gan, Zhihua Hu, Yajiao Zhou, Kehe Huang
Our previous study demonstrated that selenium could alleviate ochratoxin A (OTA)-induced nephrotoxicity in PK15 cells. Selenoprotein S (SelS) has antioxidant activities, but it is unclear whether SelS plays a role in the alleviating effects of selenium on OTA-induced nephrotoxicity. We previously have stably transfected pig pCDNA3.1-SelS to PK15 cells to overexpress SelS. Here, we demonstrated that SelS overexpression alleviated OTA-induced cytotoxicity and apoptosis as demonstrated by cell viabilities, LDH activities, Annexin V-bing, caspase 3 activities, and apoptotic nuclei...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28634058/apoptotic-gene-expression-profiles-and-dna-damage-levels-in-rat-liver-treated-with-perfluorooctane-sulfonate-and-protective-role-of-curcumin
#16
Dilek Eke, Ayla Çelik, Mehmet Bertan Yilmaz, Nurcan Aras, Sabriye Kocatürk Sel, Davut Alptekin
Perfluorinated compounds (PFCs) such as PFOS and PFOA, are xenobiotics that can be detected worldwide in the environment and humans. PFOS (C8F17SO3(-)) is a fluorinated organic compound has been used for decades in industrial and commercial products. We investigated the genotoxic and apoptotic impact of PFOS in rat liver using comet assay, micronucleus test and apoptotic gene expression methods for caspase 3, caspase 8 and the protective role of curcumin on the PFOS- induced damage under chronic exposure. In this study, rats were treated either with three different PFOS doses only (0...
June 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28631234/quality-matters-implementation-moderates-student-outcomes-in-the-paths-curriculum
#17
Neil Humphrey, Alexandra Barlow, Ann Lendrum
Analyses of the relationship between levels of implementation and outcomes of school-based social and emotional learning (SEL) interventions are relatively infrequent and are typically narrowly focused. Thus, our objective was to assess the relationship between variability in a range of implementation dimensions and intervention outcomes in the Promoting Alternative Thinking Strategies (PATHS) curriculum. Implementation of PATHS was examined in 69 classrooms across 23 schools in the first year of a major randomized controlled trial...
June 19, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28627920/reliability-and-validity-of-a-spanish-language-assessment-of-children-s-social-emotional-learning-skills
#18
Jaclyn M Russo, Clark McKown, Nicole M Russo-Ponsaran, Adelaide Allen
Few Spanish language tools are available for assessing important social-emotional learning (SEL) skills. The present study presents evidence of the psychometric properties of a Spanish-language version of SELweb (SELweb-S), a web-based system for assessing children's ability to recognize others' emotions and perspectives, solve social problems, and engage in self-control. With a sample of 524 students in Grades K to 3, we examined the reliability and validity of SELweb-S. This study provided evidence that (a) individual assessment modules exhibited moderate to high internal consistency and moderate 6-month temporal stability, (b) composite assessment scores exhibited high reliability, (c) assessment module scores fit a theoretically coherent factor structure, and (d) performance on SELweb-S assessment modules was positively related to teacher-reported SEL skills...
June 19, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28595059/coming-to-the-new-d-a-r-e-a-preliminary-test-of-the-officer-taught-elementary-keepin-it-real-curriculum
#19
L Edward Day, Michelle Miller-Day, Michael L Hecht, Desiree Fehmie
The present study reports a preliminary evaluation of D.A.R.E.'s new elementary school keepin' it REAL substance abuse prevention program. Given the widespread dissemination of D.A.R.E., this evaluation, even though of short term effects, has important implications for national prevention efforts. The new prevention curriculum teaches social and emotional competencies such as decision making and resistance skills. Social and emotional competencies and other risk factors were examined among students (N=943) in 26 classrooms, 13 classrooms in the treatment condition (n=359) and 13 classrooms in the control condition (n=584) using a quasi-experimental matched group design...
May 23, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28582663/molecular-and-epidemiological-characterization-of-staphylococcal-foodborne-outbreak-of-staphylococcus-aureus-harboring-seg-sei-sem-sen-seo-and-selu-genes-without-production-of-classical-enterotoxins
#20
Kaoru Umeda, Hiromi Nakamura, Kaori Yamamoto, Nobuko Nishina, Kiyoshi Yasufuku, Yuki Hirai, Teruo Hirayama, Kaoru Goto, Atsushi Hase, Jun Ogasawara
Staphylococcal food poisoning is the result of consumption of food contaminated with staphylococcal enterotoxins (SEs) produced by Staphylococcus aureus. To date, 23 SEs and SE-like enterotoxins (SEls) have been described in the literature. They are divided into classical SEs (SEA-SEE) and new SE/SEls (SEG-SElX). Some have proved to be foodborne-inducible, but others remain unidentified. In May 2016, at an elderly group home in Osaka city, Japan, an outbreak from foodborne pathogens occurred among lunch party participants...
May 30, 2017: International Journal of Food Microbiology
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