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https://www.readbyqxmd.com/read/29666210/regulation-and-mechanisms-of-extracellular-vesicle-biogenesis-and-secretion
#1
REVIEW
Crislyn D'Souza-Schorey, Jeffrey S Schorey
EV (extracellular vesicle) biology is a rapidly expanding field. These heterogeneous membrane vesicles, which are shed from virtually all cell types, collectively represent a new dimension of intercellular communication in normal physiology and disease. They have been shown to deliver infectious and pathogenic agents to non-infected cells whereas in cancers they are thought to condition the tumor microenvironment. Their presence in body fluids and inherent capacity for systemic delivery point to their clinical promise...
April 17, 2018: Essays in Biochemistry
https://www.readbyqxmd.com/read/29664035/out-of-pocket-expenditure-for-hospitalization-in-haryana-state-of-india-extent-determinants-financial-risk-protection
#2
Deepshikha Sharma, Shankar Prinja, Arun Kumar Aggarwal, Pankaj Bahuguna, Atul Sharma, Saroj Kumar Rana
Background & objectives: India aspires to achieve universal health coverage, which requires ensuring financial risk protection (FRP). This study was done to assess the extent of out-of-pocket (OOP) expenditure and FRP for hospitalization in Haryana State, India. Further, the determinants for FRP were also evaluated. Methods: Data collected as a part of a household level survey conducted in Haryana 'Concurrent Evaluation of National Rural Health Mission: Haryana Health Survey' were analyzed...
December 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29663859/factors-contributing-to-and-strategies-to-combat-emerging-arboviruses
#3
David Michael Callender
Less than half a century ago infectious diseases appeared to be destined to be extinguished via as a culmination of medical triumphs. As focus turned towards combating non-communicable diseases, emerging and re-emerging diseases (EIDs) have bloomed from those ashes. Five epidemic mosquito-borne arboviruses (Yellow Fever virus (YFV), Dengue virus, West Nile virus, Chikungunya virus, and Zika virus) have emerged in the recent past. Arboviruses are of the utmost importance with respect to EIDs due to intensive growth of globalisation, arthropod urban fitness/adaption, and environmental changes...
April 17, 2018: Global Public Health
https://www.readbyqxmd.com/read/29662045/macronutrient-and-major-food-group-intake-in-a-cohort-of-southern-italian-adults
#4
Serena Mulè, Mariagiovanna Falla, Alessandra Conti, Dora Castiglione, Isabella Blanco, Armando Platania, Maurizio D'Urso, Marina Marranzano
BACKGROUND: Dietary intake of macronutrient and foods is considered crucial to decrease the risk of diet-related non-communicable diseases. METHODS: The aim of this study was to describe the intake of major food groups and macronutrients in a random sample of 1838 southern Italian adults. RESULTS: No significant differences of macronutrient consumption between sexes were found. By contrast, younger individuals had significantly higher intake of animal protein than older ones...
April 15, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29661995/greater-glycaemic-response-to-an-oral-glucose-load-in-healthy-lean-active-and-young-chinese-adults-compared-to-matched-caucasians
#5
Trevor Simper, Caroline Dalton, David Broom, Waleed Ibrahim, Lingjin Li, Charles Bankole, Sisi Chen
There are ethnic differences recorded in glycaemic response and rates of type 2 diabetes mellitus (DM) between Chinese and Caucasian populations. Whether these differences are evident in matched healthy, lean, active, young adults is unclear. This study compares the postprandial glycaemic response of a group of Chinese participants ( n = 49) with a group of similar Caucasians, ( n = 48) aged 23.8 (±4.35 years), body mass index (BMI) 22.7 (±2.6) kg/m², healthy (free from non-communicable disease), and lean (body fat % 23...
April 14, 2018: Nutrients
https://www.readbyqxmd.com/read/29659851/causes-of-death-at-the-university-of-ghana-hospital-in-accra-a-37-year-review-1979-2015
#6
Edward K Sutherland, Gloria A Ansa, Frank Baiden, Enoch N B Quaye, Afua A Amoabeng, Christian Amenuveve
Background: An analysis of the causes of death in developing countries is needed to improve healthcare delivery. The aim of this study was to conduct a descriptive analysis of the causes of death at the University of Ghana Hospital from 1979 to 2015. Methods: Data were extracted from the electronic database of the University of Ghana Hospital. Diseases were grouped into three broad groups of causes of death as per the Global Burden of Disease cause list, with some diseases of epidemiological importance outlined and analysed by age, gender and time in years...
April 5, 2018: International Health
https://www.readbyqxmd.com/read/29659605/chronic-kidney-disease-in-the-global-adult-hiv-infected-population-a-systematic-review-and-meta-analysis
#7
Udeme E Ekrikpo, Andre P Kengne, Aminu K Bello, Emmanuel E Effa, Jean Jacques Noubiap, Babatunde L Salako, Brian L Rayner, Giuseppe Remuzzi, Ikechi G Okpechi
INTRODUCTION: The widespread use of antiretroviral therapies (ART) has increased life expectancy in HIV patients, predisposing them to chronic non-communicable diseases including Chronic Kidney Disease (CKD). We performed a systematic review and meta-analysis (PROSPERO registration number CRD42016036246) to determine the global and regional prevalence of CKD in HIV patients. METHODS: We searched PubMed, Web of Science, EBSCO and AJOL for articles published between January 1982 and May 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29657578/notes-from-the-field-a-case-of-hepatic-failure-and-reflections-on-current-status-of-healthcare-of-syrian-refugees-in-lebanon
#8
Salim M Saiyed, John Kahler, Mutaz Kalabani
Recent trends and research suggest health conditions of the Syrian refugees in Lebanon are deteriorating. The following case study highlights some of the problems that refugees encounter seeking health care services in Lebanon. A coordinated response from Non-governmental organization (NGO) with intense focus on non-communicable disease (NCD) is needed to avert further worsening of health conditions on the ground.
2018: Conflict and Health
https://www.readbyqxmd.com/read/29656088/-ne-nnipadua-mmpe-the-body-hates-it-exploring-the-lived-experience-of-food-allergy-in-sub-saharan-africa
#9
George A Atiim, Susan J Elliott, Ann E Clarke
Allergic diseases have closely followed the rise of non-communicable diseases (NCDs) especially in western societies. As prevalence of NCD is increasing in sub-Saharan Africa (SSA), researchers are hinting that the same future may hold for (food) allergic disease in this world region. Already, researchers are beginning to record prevalence, though with little attention to the social experience of individuals and parents with food allergic children. This paper presents the first qualitative analysis of the daily realities of adults and parents of children with allergies in SSA using Ghana as a case study...
March 23, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29653225/self-regulation-of-the-peruvian-food-industry-health-message-cues-in-the-context-of-food-and-beverage-advertisements
#10
P Busse, A Bernabé-Ortiz
OBJECTIVES: One strategy to prevent the onset of non-communicable diseases is to motivate healthy lifestyles through health media messages. In Peru, the food industry is currently implementing such strategy with health message cues, in the form of a small icon of a walking person or a healthy dish, appearing on televised food and beverage advertisements. Yet the extent of this practice is unknown. Thus, the objective of this study was three-fold: to identify (1) the food and beverage advertisements showing health cues, (2) the types of health cues, and (3) their length in time...
April 10, 2018: Public Health
https://www.readbyqxmd.com/read/29651366/height-and-weight-estimation-from-anthropometric-measurements-using-machine-learning-regressions
#11
Diego Rativa, Bruno J T Fernandes, Alexandre Roque
Height and weight are measurements explored to tracking nutritional diseases, energy expenditure, clinical conditions, drug dosages, and infusion rates. Many patients are not ambulant or may be unable to communicate, and a sequence of these factors may not allow accurate estimation or measurements; in those cases, it can be estimated approximately by anthropometric means. Different groups have proposed different linear or non-linear equations which coefficients are obtained by using single or multiple linear regressions...
2018: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29644987/preventing-and-managing-workplace-violence-against-healthcare-workers-in-emergency-departments
#12
Gabriele D'Ettorre, Vincenza Pellicani, Mauro Mazzotta, Annamaria Vullo
BACKGROUND AND AIM: Healthcare workers (HCWs) employed in Emergency Departments (EDs) frequently face with patients becoming violent because of long wait or diseases or under the influence of alcohol or drugs. Globally, workplace violence (WPV) in EDs is a major challenge to safety for HCWs, involving significant consequences to the victims, patients, and healthcare organizations. We reviewed the current literature with the aim to explore the topics focused on and to detect new evidences about approaching the issue of WPV toward HCWs in EDs...
February 21, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29643096/the-health-poverty-and-financial-consequences-of-a-cigarette-price-increase-among-500-million-male-smokers-in-13-middle-income-countries-compartmental-model-study
#13
(no author information available yet)
OBJECTIVE: To examine the impact of a 50% increase in market prices of cigarettes on health, poverty, and financial protection. DESIGN: Compartmental model study. SETTING: 13 middle income countries, totalling two billion men. PARTICIPANTS: 500 million male smokers. MAIN OUTCOME MEASURES: Life years gained, averted treatment costs, number of men avoiding catastrophic healthcare expenditures and poverty, and additional tax revenue by income group...
April 11, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29628202/health-status-of-afro-asian-refugees-in-an-italian-urban-area-a-cross-sectional-monocentric-study
#14
R Del Pinto, D Pietropaoli, U Russomando, P Evangelista, C Ferri
OBJECTIVES: The recent sociopolitical events in the Mediterranean and Middle Eastern areas have significantly impacted international migration flows. As disease prevalence and type are different among western and Afro-Asian countries, physicians dealing with refugees should be aware of their specific health needs. We aimed at evaluating the health status and disease history of refugees at their arrival in the urban area of L'Aquila (Italy). STUDY DESIGN: This is a monocentric cross-sectional study...
April 5, 2018: Public Health
https://www.readbyqxmd.com/read/29627831/decreases-of-life-expectancy-despite-decreases-in-non-communicable-disease-mortality-the-role-of-substance-use-and-socioeconomic-status
#15
Jürgen Rehm, Charlotte Probst
With the epidemiological transition, causes of death shifted from communicable to non-communicable diseases (NCDs) and life expectancy increased, as these NCD deaths occurred later in life. However, in the United States, over the past years, life expectancy has been stagnating or decreasing despite decreasing NCD mortality rates. Analyses of the most important underlying causes of death with increasing premature mortality reveal that psychoactive substance use played a crucial role for these increases. Furthermore, it can be shown, that a high proportion of the increased premature mortality and decreased life expectancies happened in lower socio-economic strata...
April 6, 2018: European Addiction Research
https://www.readbyqxmd.com/read/29627814/a-systematic-review-of-interventions-by-healthcare-professionals-to-improve-management-of-non-communicable-diseases-and-communicable-diseases-requiring-long-term-care-in-adults-who-are-homeless
#16
Peter Hanlon, Lynsey Yeoman, Lauren Gibson, Regina Esiovwa, Andrea E Williamson, Frances S Mair, Richard Lowrie
OBJECTIVE: Identify, describe and appraise trials of interventions delivered by healthcare professionals to manage non-communicable diseases (NCDs) and communicable diseases that require long-term care or treatment (LT-CDs), excluding mental health and substance use disorders, in homeless adults. DESIGN: Systematic review of randomised controlled trials (RCTs), non-RCTs and controlled before-after studies. Interventions characterised using Effective Practice and Organisation of Care (EPOC) taxonomy...
April 7, 2018: BMJ Open
https://www.readbyqxmd.com/read/29627167/investing-in-non-communicable-disease-prevention-and-management-to-advance-the-sustainable-development-goals
#17
REVIEW
Rachel Nugent, Melanie Y Bertram, Stephen Jan, Louis W Niessen, Franco Sassi, Dean T Jamison, Eduardo González Pier, Robert Beaglehole
Reduction of the non-communicable disease (NCD) burden is a global development imperative. Sustainable Development Goal (SDG) 3 includes target 3·4 to reduce premature NCD mortality by a third by 2030. Progress on SDG target 3·4 will have a central role in determining the success of at least nine SDGs. A strengthened effort across multiple sectors with effective economic tools, such as price policies and insurance, is necessary. NCDs are heavily clustered in people with low socioeconomic status and are an important cause of medical impoverishment...
April 4, 2018: Lancet
https://www.readbyqxmd.com/read/29627161/action-to-address-the-household-economic-burden-of-non-communicable-diseases
#18
REVIEW
Stephen Jan, Tracey-Lea Laba, Beverley M Essue, Adrian Gheorghe, Janani Muhunthan, Michael Engelgau, Ajay Mahal, Ulla Griffiths, Diane McIntyre, Qingyue Meng, Rachel Nugent, Rifat Atun
The economic burden on households of non-communicable diseases (NCDs), including cardiovascular diseases, cancer, respiratory diseases, and diabetes, poses major challenges to global poverty alleviation efforts. For patients with NCDs, being uninsured is associated with 2-7-fold higher odds of catastrophic levels of out-of-pocket costs; however, the protection offered by health insurance is often incomplete. To enable coverage of the predictable and long-term costs of treatment, national programmes to extend financial protection should be based on schemes that entail compulsory enrolment or be financed through taxation...
April 4, 2018: Lancet
https://www.readbyqxmd.com/read/29627160/tackling-socioeconomic-inequalities-and-non-communicable-diseases-in-low-income-and-middle-income-countries-under-the-sustainable-development-agenda
#19
REVIEW
Louis W Niessen, Diwakar Mohan, Jonathan K Akuoku, Andrew J Mirelman, Sayem Ahmed, Tracey P Koehlmoos, Antonio Trujillo, Jahangir Khan, David H Peters
Five Sustainable Development Goals (SDGs) set targets that relate to the reduction of health inequalities nationally and worldwide. These targets are poverty reduction, health and wellbeing for all, equitable education, gender equality, and reduction of inequalities within and between countries. The interaction between inequalities and health is complex: better economic and educational outcomes for households enhance health, low socioeconomic status leads to chronic ill health, and non-communicable diseases (NCDs) reduce income status of households...
April 4, 2018: Lancet
https://www.readbyqxmd.com/read/29627159/investing-in-non-communicable-diseases-an-estimation-of-the-return-on-investment-for-prevention-and-treatment-services
#20
REVIEW
Melanie Y Bertram, Kim Sweeny, Jeremy A Lauer, Daniel Chisholm, Peter Sheehan, Bruce Rasmussen, Senendra Raj Upreti, Lonim Prasai Dixit, Kenneth George, Samuel Deane
The global burden of non-communicable diseases (NCDs) is growing, and there is an urgent need to estimate the costs and benefits of an investment strategy to prevent and control NCDs. Results from an investment-case analysis can provide important new evidence to inform decision making by governments and donors. We propose a methodology for calculating the economic benefits of investing in NCDs during the Sustainable Development Goals (SDGs) era, and we applied this methodology to cardiovascular disease prevention in 20 countries with the highest NCD burden...
April 5, 2018: Lancet
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