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https://www.readbyqxmd.com/read/28449486/the-prevalence-of-pulmonary-hypertension-in-patients-with-obesity-hypoventilation-syndrome-a-prospective-observational-study
#1
Aljohara S Almeneessier, Samar Z Nashwan, Mostafa Q Al-Shamiri, Seithikurippu R Pandi-Perumal, Ahmed S BaHammam
BACKGROUND: One important cardiovascular morbidity that is associated with obesity hypoventilation syndrome (OHS) is the development of pulmonary hypertension (PH). However, few studies have assessed PH in OHS patients. Therefore, we prospectively assessed the prevalence of PH in a large sample of OHS patients. METHODS: In this prospective observational study, all consecutive OHS patients referred to the sleep disorders clinic during the study period were included...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449420/cytological-features-of-warthin-like-papillary-thyroid-carcinoma-a-case-report-with-review-of-previous-cytology-cases
#2
Archana George Vallonthaiel, Shipra Agarwal, Deepali Jain, Rajni Yadav, Nishikant A Damle
Warthin-like papillary thyroid carcinoma (WLPTC) is a rare morphological variant of papillary thyroid carcinoma which mimics various benign and malignant lesions on thyroid aspiration cytology. As correct cytological diagnosis is the cornerstone for appropriate patient management, awareness of the salient cytomorphological characteristics of this tumor is essential. Here, we present cytological features of a case of WLPTC along with discussion of the common differential diagnoses and a brief review of the literature to ascertain the most consistent cytological findings of WLPTC...
April 27, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28449244/indications-and-extent-of-central-neck-dissection-for-papillary-thyroid-cancer-an-american-head-and-neck-society-consensus-statement
#3
Nishant Agrawal, Maria R Evasovich, Emad Kandil, Salem I Noureldine, Erin A Felger, Ralph P Tufano, Dennis H Kraus, Lisa A Orloff, Raymon Grogan, Peter Angelos, Brendan C Stack, Bryan McIver, Gregory W Randolph
BACKGROUND: The primary purposes of this interdisciplinary consensus statement were to review the relevant indications for central neck dissection (CND) in patients with papillary thyroid cancer (PTC) and to outline the appropriate extent and relevant techniques required to accomplish a safe and effective CND. METHODS: A writing group convened by the American Head and Neck Society (AHNS) Endocrine Committee was tasked with identifying the important clinical elements to consider when managing the central neck compartment in patients with PTC based on available evidence in the literature, and the group's collective experience...
April 27, 2017: Head & Neck
https://www.readbyqxmd.com/read/28449113/development-of-a-new-clinical-severity-staging-system-for-patients-with-nonmetastatic-papillary-thyroid-carcinoma
#4
Omar A Karadaghy, Dorina Kallogjeri, Jay F Piccirillo
Importance: The inclusion of patient features in addition to tumor morphology provides a more holistic staging system. Objective: To identify prognostically important variables in papillary thyroid carcinoma (PTC) to incorporate into a comprehensive functional severity staging system (FSSS) and clinical severity staging system (CSSS) and to validate the model using a multi-institutional database. Design, Setting, and Participants: Retrospective cohort study of adults 18 years or older newly diagnosed or treated for nonmetastatic PTC at the Siteman Cancer Center from 1995 through 2012...
April 27, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28448992/bethesda-made-it-clearer-a-review-of-542-patients-in-a-single-institution
#5
Yunus Acar, Lütfi Doğan, H Erhan Güven, Bülent Aksel, Niyazi Karaman, Cihangir Özaslan, M Ali Gülçelik
BACKGROUND: It is essential to interpret fine needle aspiration biopsy (FNAB) material correctly to create a common language among pathologists and surgeons, leading to a uniform approach to thyroid nodule management. We aimed to compare FNAB reports of patients at our institution who were treated with total thyroidectomy, before and after the Bethesda classification system. PATIENTS AND METHODS: Patients who underwent total thyroidectomy for thyroid nodules are reviewed...
March 21, 2017: Oncology Research and Treatment
https://www.readbyqxmd.com/read/28448812/effect-of-exposure-to-p-p%C3%A2-dde-during-the-first-half-of-pregnancy-in-the-maternal-thyroid-profile-of-female-residents-in-a-mexican-floriculture-area
#6
José Ángel Hernández-Mariano, Luisa Torres-Sánchez, Susana Bassol-Mayagoitia, Maria Consuelo Escamilla-Nuñez, Mariano E Cebrian, Érika Adriana Villeda-Gutiérrez, Guadalupe López-Rodríguez, Eunice Elizabeth Félix-Arellano, Julia Blanco-Muñoz
BACKGROUND: Dichlorodiphenyldichloroethene (p,p´-DDE), the main metabolite of dichlorodiphenyltrichloroethane (DDT), has been associated with changes in human thyroid hormone levels. Maternal thyroid hormones are essential for adequate fetal neurodevelopment during the first half of pregnancy. OBJECTIVE: To evaluate the association between maternal p,p´-DDE concentration and the maternal thyroid profile during the first half of pregnancy. MATERIALS AND METHODS: We analyzed the information of 430 pregnant women from a Mexican floriculture area, with a gestational age ≤16 weeks...
April 24, 2017: Environmental Research
https://www.readbyqxmd.com/read/28448763/analysis-of-postoperative-ultrasonography-surveillance-after-hemithyroidectomy-in-patients-with-papillary-thyroid-microcarcinoma-a-multicenter-study
#7
Hye Jin Baek, Dong Wook Kim, Chang Yoon Lee, Jung Yin Huh, Jin Yong Sung, Yoon Jung Choi
OBJECTIVE: The optimal follow-up interval for postoperative ultrasonography (US) surveillance after hemithyroidectomy in patients with papillary thyroid microcarcinoma (PTMC) is unclear. The purpose of this study was to evaluate the prevalence of tumor recurrence/persistence and to investigate the appropriateness of postoperative US surveillance in PTMC patients who underwent hemithyroidectomy. METHODS: Our institutional review board approved this retrospective study...
April 27, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28448759/ft3-is-higher-in-males-than-in-females-and-decreases-over-the-lifespan
#8
David Strich, Gilad Karavani, Shalom Edri, Cherut Chay, David Gillis
OBJECTIVE: Normal changes in Free triiodothyronine (FT3), Free thyroxine (FT4) and thyroid stimulating hormone (TSH) levels over the lifespan and differences between genders are not well documented, mainly because even the largest-scale studies available include relatively small cohorts. The aim of this study was to define age-related trends including gender differences based on reliable data. METHODS: A large database including serum thyroid tests drawn in community clinics was studied...
April 27, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28448653/exclusion-of-eligible-indeterminate-thyroid-nodules-in-estimates-of-negative-predictive-value-for-the-gene-expression-classifier
#9
Quan-Yang Duh, Catherine Rahilly-Tierney, Hossein Gharib
No abstract text is available yet for this article.
April 27, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28448647/exclusion-of-eligible-indeterminate-thyroid-nodules-in-estimates-of-negative-predictive-value-for-the-gene-expression-classifier
#10
Zaid Al-Qurayshi, Andrew B Sholl, Emad Kandil
No abstract text is available yet for this article.
April 27, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28448414/computed-tomography-features-of-benign-and-malignant-calcified-thyroid-nodules-a-single-center-study
#11
Donghyun Kim, Dong Wook Kim, Young Jin Heo, Jin Wook Baek, Yoo Jin Lee, Young Mi Park, Hye Jin Baek, Soo Jin Jung
OBJECTIVE: No previous studies have investigated thyroid calcification on computed tomography (CT) quantitatively by using Hounsfield unit (HU) values. This study aimed to analyze quantitative HU values of thyroid calcification on preoperative neck CT and to assess the characteristics of benign and malignant calcified thyroid nodules (CTNs). MATERIALS AND METHODS: Two hundred twenty patients who underwent neck CT before thyroid surgery from January 2015 to June 2016 were included...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448252/hypothyroidism-in-carcinoma-of-the-tongue-with-adjuvant-treatment
#12
Sabita Kumari, Jonathan Gondi, Hemantkumar Nemade, L M Chandra Sekhara Rao, Deleep Gudipudi, T Subramanyeshwar Rao
OBJECTIVE: The objective of this study was to evaluate the incidence of hypothyroidism with adjuvant treatment in oral tongue carcinoma patients treated primarily with surgery. MATERIALS AND METHODS: A retrospective review was carried out to analyze hypothyroidism incidence and its relation to adjuvant treatment (radiation/radio-chemotherapy) in oral tongue carcinoma after the primary surgical ablation and neck dissection. Hypothyroidism was analyzed in relation with dose of radiation, gender, and adjuvant treatment modality...
March 29, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28448064/changes-in-thyroid-hormone-concentrations-during-neonatal-extracorporeal-membrane-oxygenation
#13
L Leeuwen, A F J van Heijst, J van Rosmalen, Y B de Rijke, L W J E Beurskens, D Tibboel, E L T van den Akker, H IJsselstijn
OBJECTIVE: Thyroid hormone concentrations can be disturbed during critical illness. Our aim was to determine changes in thyroid hormone concentrations during neonatal extracorporeal membrane oxygenation (ECMO). STUDY DESIGN: We included 21 ECMO-treated neonates. Age-specific s.d. scores (SDS) of free and total thyroxine (FT4; TT4), reverse and total triiodothyronine (rT3; TT3), thyroid-stimulating hormone (TSH) and thyroxine-binding globulin (TBG) were determined at six fixed time-points...
April 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28447904/fine-needle-aspiration-versus-frozen-section-in-the-evaluation-of-malignant-thyroid-nodules-in-patients-with-the-diagnosis-of-suspicious-for-malignancy-or-malignancy-by-fine-needle-aspiration
#14
Qin Ye, Jennifer S Woo, Qunzi Zhao, Ping Wang, Pintong Huang, Lirong Chen, Xin Li, Kanlun Xu, Ying Yong, Stephanie Sung-Eun Yang, Jianyu Rao
CONTEXT: - The Bethesda System for Reporting Thyroid Cytopathology recommends against the use of intraoperative frozen section (FS) during lobectomy of a thyroid nodule with a fine-needle aspiration (FNA) diagnosis of malignant. Bethesda recommendations for FS in the FNA category of suspicious for malignancy (SFM) is less well-defined. In some institutions in China, FS examination is performed during lobectomy even for FNA-proven malignant cases. OBJECTIVE: - -To compare the efficacy of FNA versus FS in the evaluation of malignant thyroid lesions...
May 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28447753/antitumor-activity-of-fucoidan-in-anaplastic-thyroid-cancer-via-apoptosis-and-anti-angiogenesis
#15
Hong-Yan Shen, Lan-Zhen Li, Ke-Cheng Xue, Dan-Dan Hu, Yu-Jun Gao
The present study demonstrated the effect of fucoidan, isolated from Fucus vesiculosus, on cell growth and apoptosis in anaplastic thyroid cancer cells. The cell viability was analyzed using a Cell Counting Kit‑8 cell proliferation kit. Diamidino-2-phenylindole and terminal deoxynucleotidyl transferase-mediated dUTP nick‑end labeling assays were used to examine the apoptotic effect of fucoidan, which revealed the presence of apoptotic bodies and DNA fragmentation. Fucoidan inhibited the growth of FTC133 and TPC1 ATC cells in a dose‑dependent manner...
March 16, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28447590/concomitant-thyroid-cancer-in-patients-with-primary-hyperparathyroidism-in-an-endemic-goitre-region
#16
Besir Simsek, Cem Emir Guldogan, Sabri Ozden, Baris Saylam, Serif Melih Karabeyoglu, Mesut Tez
OBJECTIVE: Primary hyperparathyroidism (pHPT) is often accompanied by underlying thyroid pathology and 1 to 36% of these thyroid pathologies are malignant. How the identification of these lesions affects patient management is unclear. We present a single-center experience with the prevalence of concomitant thyroid cancer in patients who underwent parathyroidectomy for pHPT. MATERIALS AND METHODS: This was a retrospective cohort study. Two hundred-two patients with primary hyperparathyroidism included study...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28447527/serum-thyroid-hormone-levels-among-chinese-pregnant-women
#17
Yunxian Yu, Xiawei Li, Shuying Jiang, Wen Jiang, Jinhua Wu, Zhaopin Wang, Shuojia Wang, Minchao Li, Haigeng Xu, Yun Lv, Jinxing Jiang, Yongfeng Ding, Boer Zhang
AIM: The aim of this study is to examine gestational serum thyroid hormone levels and influencing factors among Chinese pregnant women with high dietary iodine intake. METHODS: The study was conducted from 2011 and 2013 in Zhoushan Women & Children's Hospital, Zhejiang, China. A total of 1991 pregnant women were enrolled and their serum levels of free thyroid hormones (FT4, FT3, and TSH) were detected by chemiluminescence method. RESULTS: Gestational serum FT4 and FT3 decreased with gestational week while TSH increased...
April 27, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28447444/maternal-thyroid-function-in-women-undergoing-controlled-ovarian-hyperstimulation-during-in-vitro-fertilization-and-its-relation-to-reproductive-outcome
#18
Abdul K Abdul Karim, Muhammad Azrai Abu, Buvanes Chelliah, Zainul R Mohd Razi, Mohd H Omar, Hanita Othman, Zuraidah C Man
BACKGROUND: We conducted a study to evaluate the changes in thyroid function during Controlled Ovarian Hyperstimulation (COH) and its association with the outcome of assisted reproductive technique (ART). METHODS: This is a prospective cohort study done in University Hospital Fertility clinic for one year duration. A total of eighty eight euthyroid women who underwent COH as part of planned in vitro fertilization were invited to participate in this study. Serum thyroid function of each women will be monitored before stimulation (T1), day 10 -13 of cycle (T2), during oocyte retrieval (T3), one week following embryo transfer (T4) and at four weeks post embryo transfer(T5)...
April 26, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28447158/-ultrasound-diagnostics-in-sj%C3%A3-gren-s-syndrome
#19
REVIEW
V S Schäfer, W A Schmidt
Ultrasound of the salivary glands is a specific examination for detecting pathology of salivary glands in the diagnosis of Sjögren's syndrome. It is easy to learn, rapidly performed, non-invasive and inexpensive. Other imaging techniques, such as sialography and scintigraphy, are currently only rarely performed. For the examination, linear ultrasound probes with frequencies between 7 and 12 MHz are recommended. Such probes are already widely available to the rheumatologist performing musculoskeletal ultrasound...
April 26, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28447112/-imaging-diagnostics-of-breast-metastases-from-extramammary-tumors
#20
REVIEW
S Wienbeck, S Nemat, J Lotz, A Surov
Breast metastases of solid extramammary tumors are very rare in comparison to primary malignancies of the breast and account for only 0.33-6.3% of all malignant neoplasms of the breast. The most common primary tumors are malignant melanoma, distant sarcomas, lung cancer, ovarian cancer, renal cell cancer and thyroid cancer in decreasing order of frequency. This review article summarizes the clinical features and the different imaging findings of breast metastases from different extramammary solid tumors. Breast metastases are often incidental findings in computed tomography (CT) or positron emission tomography CT (PET-CT) imaging...
April 26, 2017: Der Radiologe
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