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https://www.readbyqxmd.com/read/28447938/low-serum-selenium-concentrations-in-french-patients-with-measles
#1
M Garcia, A Pineau, O Guillard, S Ragot, N Lévêque, G Agius
OBJECTIVE: Selenium deficiency adversely affects the clinical outcome of measles in the tropics. In developed countries, serum selenium level has never been investigated during acute measles. The aim of this study was to determine serum selenium concentrations in French patients with acute measles and to seek correlations with clinical and virological findings. PATIENTS AND METHODS: We studied serum selenium concentrations in 94 French patients with acute measles and in 99 healthy controls matched for age and sex...
November 9, 2016: Current Research in Translational Medicine
https://www.readbyqxmd.com/read/28446847/knowledge-experiences-and-training-needs-of-health-professionals-about-disaster-preparedness-and-response-in-southwest-ethiopia-a-cross-sectional-study
#2
Negalign Berhanu, Hailay Abrha, Yohannes Ejigu, Kifle Woldemichael
BACKGROUND: Over the past decade, the magnitude and intensity of disasters have been vividly rising globally due to the forces of nature or man. This study aimed at assessing the perceived knowledge, experiences and training needs of health professionals regarding disasters, their prevention and management in Jimma Zone, Southwest Ethiopia. METHODS: An institution based cross-sectional survey was conducted on 377 health professionals taken from 9 randomly selected districts out of 18...
September 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28446173/impact-of-the-ebola-outbreak-on-routine-immunization-in-western-area-sierra-leone-a-field-survey-from-an-ebola-epidemic-area
#3
Xiaojin Sun, T T Samba, Jianyi Yao, Wenwu Yin, Lin Xiao, Fuqiang Liu, Xiaoqiang Liu, Jikun Zhou, Zengqiang Kou, Hongwei Fan, Hao Zhang, Aqnes Williams, Paul M Lansana, Zundong Yin
BACKGROUND: Since March 2014, the Ebola Virus Disease (EVD) outbreak in West Africa disrupted health care systems - especially in Guinea, Liberia and Sierra Leone - with a consequential stress on the area's routine immunization programs. To address perceived decreased vaccination coverage, Sierra Leone conducted a catch-up vaccination campaign during 24-27 April 2015. We conducted a vaccination coverage survey and report coverage estimates surrounding the time of the EVD outbreak and the catch-up campaign...
April 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28441361/immunization-strategies-targeting-newly-arrived-migrants-in-non-eu-countries-of-the-mediterranean-basin-and-black-sea
#4
Cristina Giambi, Martina Del Manso, Maria Grazia Dente, Christian Napoli, Carmen Montaño-Remacha, Flavia Riccardo, Silvia Declich, Network For The Control Of Cross-Border Health Threats In The Mediterranean Basin And Black Sea For The ProVacMed Project
Background: The World Health Organization recommends that host countries ensure appropriate vaccinations to refugees, asylum seekers and migrants. However, information on vaccination strategies targeting migrants in host countries is limited. Methods: In 2015-2016 we carried out a survey among national experts from governmental bodies of 15 non-EU countries of the Mediterranean and Black Sea in order to document and share national vaccination strategies targeting newly arrived migrants. Results: Four countries reported having regulations/procedures supporting the immunization of migrants at national level, one at sub-national level and three only targeting specific population groups...
April 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28441062/measles-cases-among-adolescents-in-southern-pakistan-2012-2015-the-case-for-revisiting-vaccination-strategies
#5
Sadia Shakoor, Erum Khan, Muhammad Imran Rajput, Wali Muhammad Rahimoon
AIMS: Surveillance of adult measles in Pakistan is a challenge as it does not enjoy the status of a reportable disease unlike childhood cases and therefore cases remain undetected and unreported or misdiagnosed. Consequently no data or estimates of young adult cases, seroprevalence, or estimates of susceptible preadolescent or young adult population exist. We have presented both laboratory conformed and clinically suspected cases of measles occurring in adolescents and adults in the southern province of Sindh in Pakistan...
April 25, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28439108/phase-i-trial-of-systemic-administration-of-edmonston-strain-of-measles-virus-genetically-engineered-to-express-the-sodium-iodide-symporter-in-patients-with-recurrent-or-refractory-multiple-myeloma
#6
A Dispenzieri, C Tong, B LaPlant, M Q Lacy, K Laumann, D Dingli, Y Zhou, M J Federspiel, M A Gertz, S Hayman, F Buadi, M O'Connor, V J Lowe, K-W Peng, S J Russell
MV-NIS is an Edmonston-lineage oncolytic measles virus expressing the human sodium-iodide symporter--a means for monitoring by noninvasive imaging of radioiodine. Patients with relapsed, refractory myeloma who had explored all other treatment options were eligible for this Phase I trial. Cohort 1 was treated with intravenous MV-NIS, and Cohort 2 received cyclophosphamide two days prior to MV-NIS. Thirty-two patients were treated. Cohort 1 initially enrolled to 4 dose-levels without reaching MTD and subsequently to 2 higher dose-levels when improved virus manufacture technology made it possible...
April 25, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/28434402/implementing-the-communication-for-development-strategy-to-improve-knowledge-and-coverage-of-measles-vaccination-in-western-chinese-immunization-programs-a-before-and-after-evaluation
#7
Ming Lu, Yao-Zhu Chu, Wen-Zhou Yu, Robert Scherpbier, Yu-Qing Zhou, Xu Zhu, Qi-Ru Su, Meng-Juan Duan, Xuan Zhang, Fu-Qiang Cui, Hua-Qing Wang, Yi-Biao Zhou, Qing-Wu Jiang
BACKGROUND: Communication for Development (C4D) is a strategy promoted by the United Nations Children's Fund to foster positive and measurable changes at the individual, family, community, social, and policy levels of society. In western China, C4D activities have previously been conducted as part of province-level immunization programs. In this study, we evaluated the association of C4D with changes in parental knowledge of immunization services, measles disease, and measles vaccine, and changes in their children's measles vaccine coverage...
April 24, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28434128/aspects-on-the-history-of-transmission-and-favor-of-distribution-of-viruses-by-iatrogenic-action-perhaps-an-example-of-a-paradigm-of-the-worldwide-spread-of-hiv
#8
REVIEW
Lutz G Gürtler, Josef Eberle
Transmission of infectious agents might be associated with iatrogenic actions of charitable help in health care. An example is the vaccination against yellow fever in USA that transmitted hepatitis B virus. Another example is injections of praziquantel for treatment and cure of schistosomiasis in Central and Northern Africa, with a focus in Egypt that has spread hepatitis C virus. There is no indication that human T-lymphotropic virus type 1 was spread by injection treatment for African trypanosomiasis, syphilis and treponematosis, but these treatments might have contributed to the early spread of human immunodeficiency virus type 1 (HIV-1) in Central Africa...
April 22, 2017: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/28433329/measles-epidemics-and-seroepidemiology-of-population-in-wujin-changzhou-city-jiangsu-province-china-2015
#9
Lingyan Tang, Yihong Zhou, Yingzi Pan, Hongming Zhu
The measles epidemic was rather severe in Wujin 2015, and a seroprevalence survey of measles antibody was conducted during June to September 2015 in Wjin district of Changzhou city. Blood samples were collected from community health population and convenient samples of residual blood from hospitals. Measles-specific IgG levels were measured by ELISA assay. A total of 122 measles cases were reported 2015 in Wujin district with an incidence of 8.31 per 100000 populations. A large proportion of measles cases were adults ≥20years (62...
April 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28432975/vaccination-strategies-against-zika-virus
#10
REVIEW
Estefania Fernandez, Michael S Diamond
The epidemic emergence of Zika virus (ZIKV) in 2015-2016 has been associated with congenital malformations and neurological sequela. Current efforts to develop a ZIKV vaccine build on technologies that successfully reduced infection or disease burden against closely related flaviviruses or other RNA viruses. Subunit-based (DNA plasmid and modified mRNA), viral vectored (adeno- and measles viruses) and inactivated viral vaccines are already advancing to clinical trials in humans after successful mouse and non-human primate studies...
April 19, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28432101/polio-and-measles-down-the-drain-environmental-enterovirus-surveillance-in-the-netherlands-2005-2015
#11
Kimberley S M Benschop, Harrie G van der Avoort, Edin Jusic, Harry Vennema, Rob van Binnendijk, Erwin Duizer
Polioviruses (PV) are members of the genus Enterovirus (EV). In the Netherlands, the exclusion of PVcirculation is based on Clinical EV Surveillance (CEVS) of EV positive cases and routine Environmental EV Surveillance (EEVS) conducted on sewage samples collected in the region of the Netherlands where vaccination coverage is low due to religious reason.We compared the EEVS data to those of the CEVS to gain insight in the relevance of EEVS for poliovirus and non-polio enterovirus surveillance. Following the polio outbreak in Syria, EEVS was performed at the Primary Refugee Center Ter Apel in the Netherlands and data were compared to CEVS and EEVS...
April 21, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28431124/childhood-vaccinations-and-risk-of-acute-lymphoblastic-leukaemia-in-children
#12
Signe Holst Søegaard, Klaus Rostgaard, Kjeld Schmiegelow, Mads Kamper-Jørgensen, Marie Hargreave, Henrik Hjalgrim, Anders Hviid
Background: It has been proposed that childhood vaccinations protect against acute lymphoblastic leukaemia (ALL) in children by modulation of future responses to common infections in childhood. However, the available studies provide inconsistent findings, and population-based cohort studies with longitudinal information on vaccinations are lacking. Methods: In a register-based cohort of all children born in Denmark from 1 January 1990 to 31 December 2008, followed up until age 15 years or 31 December 2009 ( n  = 1 225 404), we evaluated exposure to childhood vaccination and risk of childhood ALL, including information on ALL subtypes...
April 19, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28428878/immunization-dropout-rate-and-data-quality-among-children-12-23-months-of-age-in-ghana
#13
Benjamin Baguune, Joyce Aputere Ndago, Martin Nyaaba Adokiya
BACKGROUND: Immunization against diseases is one of the most important public health interventions with cost effective means to preventing childhood morbidity, mortality and disability. However, a proportion of children particularly in Africa are not fully immunized with the recommended vaccines. Thus, many children are still susceptible to the Expanded Program on Immunization (EPI) targeted diseases. The objective of this study was to determine the immunization dropout rate and data quality among children aged 12-23 months in Techiman Municipality, Ghana...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28426447/measles-cases-in-children-requiring-hospital-access-in-an-academic-pediatric-hospital-in-italy-2008-2013
#14
Marta Ciofi Degli Atti, Antonietta Filia, Antonino Bella, Annamaria Sisto, Maria Antonietta Barbieri, Antonino Reale, Massimiliano Raponi
BACKGROUND: The Lazio Region is one of the Italian regions where sustained measles transmission continues to occur. We investigated measles cases reported by the Emergency Department (ED) of the largest pediatric hospital in Italy, located in Lazio. METHODS: We reviewed clinical records of all measles cases from 0 to 18 years of age evaluated in the ED in 2008-2013. We compared demographic and clinical characteristics of patients admitted to the inpatient setting with those of patients discharged home, to assess possible determinants of hospital admission...
April 18, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28421976/-measles-after-mmr-vaccination
#15
R van Grootveld, L M Klitsie, D C M van der Kaay, A C T M Vossen, A C Dijkmans
BACKGROUND: The Dutch national vaccination program provides vaccination for mumps, measles and rubella (MMR vaccine) for all children. After vaccination with live attenuated viruses, the virus replicates on a limited scale. Replication may lead to mild symptoms occurring 5-14 days after MMR-vaccination, including fever, conjunctivitis and rash. Symptoms are comparable to those of a wildtype measles infection. CASE DESCRIPTION: A 14-month-old boy was admitted to the hospital with an impressive rash 13 days after MMR-vaccination...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28420160/global-transmission-dynamics-of-measles-in-the-measles-elimination-era
#16
Yuki Furuse, Hitoshi Oshitani
Although there have been many epidemiological reports of the inter-country transmission of measles, systematic analysis of the global transmission dynamics of the measles virus (MV) is limited. In this study, we applied phylogeographic analysis to characterize the global transmission dynamics of the MV using large-scale genetic sequence data (obtained for 7456 sequences) from 115 countries between 1954 and 2015. These analyses reveal the spatial and temporal characteristics of global transmission of the virus, especially in Australia, China, India, Japan, the UK, and the USA in the period since 1990...
April 16, 2017: Viruses
https://www.readbyqxmd.com/read/28419512/predicting-receptor-functionality-of-signaling-lymphocyte-activation-molecule-for-measles-virus-hemagglutinin-from-docking-simulation
#17
Yoshiyuki Suzuki
Predicting susceptibility to a virus in various species is desirable for risk assessment of interspecies transmission. For screening of susceptibility, it may be useful to evaluate the receptor functionality. Here the docking simulation was conducted for measles virus hemagglutinin (MV-H) and immunoglobulin-like variable domain of signaling lymphocyte activation molecule (SLAM-V). It wasobserved that the docking score of MV-H and SLAM-V was correlated with the activity of SLAM as MV receptor. These results suggest that the receptor functionality may be predicted from the docking score of virion surface proteins and cellular receptor molecules...
April 17, 2017: Microbiology and Immunology
https://www.readbyqxmd.com/read/28417983/an-approach-to-and-web-based-tool-for-infectious-disease-outbreak-intervention-analysis
#18
Ashlynn R Daughton, Nicholas Generous, Reid Priedhorsky, Alina Deshpande
Infectious diseases are a leading cause of death globally. Decisions surrounding how to control an infectious disease outbreak currently rely on a subjective process involving surveillance and expert opinion. However, there are many situations where neither may be available. Modeling can fill gaps in the decision making process by using available data to provide quantitative estimates of outbreak trajectories. Effective reduction of the spread of infectious diseases can be achieved through collaboration between the modeling community and public health policy community...
April 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28415019/recovery-of-infective-virus-particles-in-ion-exchange-and-hydrophobic-interaction-monolith-chromatography-is-influenced-by-particle-charge-and-total-to-infective-particle-ratio
#19
Dora Sviben, Dubravko Forcic, Jelena Ivancic-Jelecki, Beata Halassy, Marija Brgles
Viral particles are used in medical applications as vaccines or gene therapy vectors. In order to obtain product of high purity, potency and safety for medical use purification of virus particles is a prerequisite, and chromatography is gaining increased attention to meet this aim. Here, we report on the use of ion-exchange and hydrophobic interaction chromatography on monolithic columns for purification of mumps virus (MuV) and measles virus (MeV). Efficiency of the process was monitored by quantification of infective virus particles (by 50% cell culture infective dose assay) and total virus particles, and monitoring of their size (by Nanoparticle Tracking Analysis)...
April 8, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28414002/global-importation-and-population-risk-factors-for-measles-in-new-zealand-a-case-study-for-highly-immunized-populations
#20
D T S Hayman, J C Marshall, N P French, T E Carpenter, M G Roberts, T Kiedrzynski
As endemic measles is eliminated through immunization, countries must determine the risk factors for the importation of measles into highly immunized populations to target control measures. Despite eliminating endemic measles, New Zealand suffers from outbreaks after introductions from abroad, enabling us to use it as a model for measles introduction risk. We used a generalized linear model to analyze risk factors for 1137 measles cases from 2007 to June 2014, provide estimates of national immunity levels, and model measles importation risk...
April 17, 2017: Epidemiology and Infection
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