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https://www.readbyqxmd.com/read/29337931/real-time-spectroscopic-ellipsometry-analysis-of-first-stage-cuin1-xgaxse%C3%A2-growth-indium-gallium-selenide-co-evaporation
#1
Puja Pradhan, Puruswottam Aryal, Dinesh Attygalle, Abdel-Rahman Ibdah, Prakash Koirala, Jian Li, Khagendra P Bhandari, Geethika K Liyanage, Randy J Ellingson, Michael J Heben, Sylvain Marsillac, Robert W Collins, Nikolas J Podraza
Real time spectroscopic ellipsometry (RTSE) has been applied for in-situ monitoring of the first stage of copper indium-gallium diselenide (CIGS) thin film deposition by the three-stage co-evaporation process used for fabrication of high efficiency thin film photovoltaic (PV) devices. The first stage entails the growth of indium-gallium selenide (In1-xGax)₂Se₃ (IGS) on a substrate of Mo-coated soda lime glass maintained at a temperature of 400 °C. This is a critical stage of CIGS deposition because a large fraction of the final film thickness is deposited, and as a result precise compositional control is desired in order to achieve the optimum performance of the resulting CIGS solar cell...
January 16, 2018: Materials
https://www.readbyqxmd.com/read/29306476/the-cha2ds2-vasc-score-strongly-correlates-with-glomerular-filtration-rate-and-predicts-renal-function-decline-over-time-in-elderly-patients-with-atrial-fibrillation-and-chronic-kidney-disease
#2
Jan Beyer-Westendorf, Reinhold Kreutz, Florian Posch, Cihan Ay
BACKGROUND: The decline of renal function affects stroke risk in patients with atrial fibrillation (AF). Here, we aim to study the predictive value of the CHA2DS2-VASc score, a stroke-risk stratification model in AF, for renal function and renal decline in patients with AF and chronic kidney disease (CKD). METHODS: Two electronic health record cohorts with AF and CKD stage III/IV were evaluated (Cohort #1 (IMS-DA, Germany): 18,539 patients with 125,149 estimated glomerular filtration rate (eGFR) measurements; Cohort #2 (IMS-THIN, United Kingdom): 18,240 patients with 133,676 eGFR measurements)...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29296099/can-information-on-functional-and-cognitive-status-improve-short-term-mortality-risk-prediction-among-community-dwelling-older-people-a-cohort-study-using-a-uk-primary-care-database
#3
Janet Sultana, Andrea Fontana, Francesco Giorgianni, Giorgio Basile, Elisabetta Patorno, Alberto Pilotto, Mariam Molokhia, Robert Stewart, Miriam Sturkenboom, Gianluca Trifirò
Background: Functional and cognitive domains have rarely been evaluated for their prognostic value in general practice databases. The aim of this study was to identify functional and cognitive domains in The Health Improvement Network (THIN) and to evaluate their additional value for the prediction of 1-month and 1-year mortality in elderly people. Materials and methods: A cohort study was conducted using a UK nationwide general practitioner database. A total of 1,193,268 patients aged 65 years or older, of whom 15,300 had dementia, were identified from 2000 to 2012...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29273660/prevalence-and-trends-of-thinness-overweight-and-obesity-among-children-and-adolescents-aged-3-18-years-across-europe-a-protocol-for-a-systematic-review-and-meta-analysis
#4
Miriam Garrido-Miguel, Iván Cavero-Redondo, Celia Álvarez-Bueno, Fernando Rodriguez-Artalejo, Luis Moreno Aznar, Jonatan R Ruiz, Vicente Martinez-Vizcaino
INTRODUCTION: Increasing prevalence of both thinness and excess weight during childhood and adolescence is a significant public health issue because of short-term health consequences and long-term tracking of weight status. Monitoring weight status in Europe may serve to identify countries and regions where rates of these disorders are either slowing down or increasing to evaluate recent policies aimed at appropriate body weight, and to direct future interventions. This study protocol provides a standardised and transparent methodology to improve estimating trends of thinness, overweight and obesity in children aged 3-18 years and adolescents across the European region between 2000 and 2017...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29250905/validity-of-diagnostic-codes-to-identify-hospitalizations-for-infections-among-patients-treated-with-oral-anti-diabetic-drugs
#5
M Elle Saine, Mona Gizaw, Dena M Carbonari, Craig W Newcomb, Jason A Roy, Serena Cardillo, Daina B Esposito, Harshvinder Bhullar, Arlene M Gallagher, Brian L Strom, Vincent Lo Re
PURPOSE: Identification of hospitalizations for infection is important for post-marketing surveillance of drugs, but the validity of using diagnosis codes to identify these events is unknown. Differentiating between hospitalization for and with infection is important, as the latter is common and less likely to arise from pre-admission exposure to drugs. We determined positive predictive values (PPVs) of diagnostic coding-based algorithms to identify hospitalization for infection among patients prescribed oral anti-diabetic drugs (OADs)...
December 18, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29243399/diabetic-foot-ulcer-management-in-clinical-practice-in-the-uk-costs-and-outcomes
#6
Julian F Guest, Graham W Fuller, Peter Vowden
The aim of this study was to estimate the patterns of care and annual levels of health care resource use attributable to managing diabetic foot ulcers (DFUs) in clinical practice by the UK's National Health Service (NHS), and the associated costs of patient management. This was a retrospective cohort analysis of the records of 130 patients with a newly diagnosed DFU in The Health Improvement Network (THIN) database. Patients' characteristics, wound-related health outcomes and health care resource use were quantified, and the total NHS cost of patient management was estimated at 2015-2016 prices...
December 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29243398/venous-leg-ulcer-management-in-clinical-practice-in-the-uk-costs-and-outcomes
#7
Julian F Guest, Graham W Fuller, Peter Vowden
The aim of this study was to estimate the patterns of care and annual levels of health care resource use attributable to managing venous leg ulcers (VLUs) in clinical practice by the UK's National Health Service (NHS) and the associated costs of patient management. This was a retrospective cohort analysis of the records of 505 patients in The Health Improvement Network (THIN) Database. Patients' characteristics, wound-related health outcomes and health care resource use were quantified, and the total NHS cost of patient management was estimated at 2015/2016 prices...
December 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29229337/receptor-protein-of-lysinibacillus-sphaericus-mosquito-larvicidal-toxin-displays-amylomaltase-activity
#8
Mahima Sharma, Gagan D Gupta, Vinay Kumar
The activated binary toxin (BinAB) from Lysinibacillus sphaericus binds to surface receptor protein (Cqm1) on the midgut cell membrane and kills Culex quinquefasciatus larvae on internalization. Cqm1 is attached to cells via a glycosyl-phosphatidylinositol (GPI) anchor. It has been classified as a member of glycoside hydrolase family 13 of the CAZy database. Here, we report characterization of the ordered domain (residues 23-560) of Cqm1. Gene expressing Cqm1 of BinAB susceptible mosquito was chemically synthesized and the protein was purified using E...
December 8, 2017: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29228646/discordance-of-pathological-thin-melanoma-thickness-and-t-stage-in-seer-registry-impacts-on-clinical-management-and-research-directions
#9
Zhichao Wang, Haizhou Li, Xinyang Liu, Jinhong Bae, Xin Huang, Yashan Gao, Xiangwen Xu, Jihan Guo, Lin Lu, Tao Zan, Qingfeng Li
Background: Ultrathin melanoma was previously demonstrated to have higher risk for melanoma-specific mortality using SEER database. However, these guideline-changing conclusions has been recently challenged by miscoding of thickness. This present study was performed to assess the prognosis of thin and ultrathin melanoma using only surgically-treated, pathologically confirmed and after removal of discordant cases. Methods: Melanoma patients from SEER database who were initially diagnosed with histologically confirmed and surgically treated melanoma from 1998 to 2012 were included...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29228207/effectiveness-of-live-attenuated-influenza-vaccine-in-preventing-amoxicillin-prescribing-in-preschool-children-a-self-controlled-case-series-study
#10
Pia Hardelid, Yonas Ghebremichael-Weldeselassie, Heather Whitaker, Greta Rait, Ruth Gilbert, Irene Petersen
Objectives: To determine the effectiveness of live attenuated influenza vaccine (LAIV) in reducing amoxicillin prescribing in preschool children in primary care. Patients and methods: We used The Health Improvement Network (THIN), a large primary care database from the United Kingdom. We included children aged 2 to 4 years old at the start of either the 2013/14 or the 2014/15 winter season, with at least one amoxicillin prescription between September and May, irrespective of LAIV vaccination status...
December 8, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29215795/uterine-caesarean-closure-techniques-affect-ultrasound-findings-and-maternal-outcomes-a-systematic-review-and-meta-analysis
#11
S I Stegwee, I P M Jordans, L F van der Voet, P M van de Ven, J C F Ket, C B Lambalk, C J M de Groot, W J K Hehenkamp, J A F Huirne
BACKGROUND: Caesarean section (CS) rates are rising globally. Long-term adverse outcomes after CS might be reduced when the optimal uterine closure technique becomes evident. OBJECTIVE: To determine the effect of uterine closure techniques after CS on maternal and ultrasound outcomes. SEARCH STRATEGY: Literature search in electronic databases. SELECTION CRITERIA: Randomised controlled trials (RCTs) or prospective cohort studies that evaluated uterine closure techniques and reported on ultrasound findings, perioperative or long-term outcomes...
December 7, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29202638/a-systematic-scoping-review-of-engagement-in-physical-activity-among-lgbtq-adults
#12
Shannon S C Herrick, Lindsay R Duncan
BACKGROUND: LGBTQ+ (lesbian, gay, bisexual, transgender, queer, etc) persons are subject to elevated rates of chronic diseases and health concerns that can be addressed through regular participation in physical activity. However, LGBTQ+ adults experience unique challenges to engaging in physical activity. Subsequently, the aim of this study is to describe the dominant narratives related to the complex intersection of sexual orientation, gender identity, and physical activity. METHODS: A systematic search and scoping review of existing literature was conducted in June 2016...
December 4, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/29200709/total-knee-arthroplasty-in-young-patients-factors-predictive-of-aseptic-failure-in-the-2nd-4th-decade
#13
Tristan Camus, William J Long
Objective: In a recently published article we reviewed our long term outcomes of TKA in young patients (<55) with end stage OA. The purpose of this study was to identify what additional factors may predict aseptic failure in these young patients. Methods: A retrospective review of all patients in our young TKA database was performed, and included failure only for mechanical wear and loosening. Results: The IB-II prosthesis, a thin polyethylene (<9 mm), and higher Knee Society functional class at midterm follow-up was associated with higher failure rate...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29198779/mitotic-rate-is-associated-with-positive-lymph-nodes-in-thin-melanomas
#14
Lee Wheless, Chelsea A Isom, Mary A Hooks, Rondi M Kauffmann
BACKGROUND: The American Joint Commission on Cancer will remove mitotic rate from its staging guidelines in 2018. OBJECTIVE: Using a large nationally-representative cohort, we examined the association between mitotic rate and lymph node positivity among thin melanomas. METHODS: 149,273 thin melanomas in the National Cancer Database were examined for their association between high-risk features of mitotic rate, ulceration, and Breslow depth, with lymph node status...
November 30, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29194673/transected-thin-melanoma-implications-for-sentinel-lymph-node-staging
#15
Garth Herbert, Giorgos C Karakousis, Edmund K Bartlett, Salman Zaheer, Danielle Graham, Brian J Czerniecki, Douglas L Fraker, Charlotte Ariyan, Daniel G Coit, Mary S Brady
BACKGROUND AND OBJECTIVES: Indications for sentinel lymph node (SLN) biopsy in patients with thin melanoma (≤1 mm thick) are controversial. We asked whether deep margin (DM) positivity at initial biopsy of thin melanoma is associated with SLN positivity. METHODS: Cases were identified using prospectively maintained databases at two melanoma centers. Patients who had undergone SLN biopsy for melanoma ≤1 mm were included. DM status was assessed for association with SLN metastasis in univariate and multivariate analyses...
November 30, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29165992/quantitative-chemical-analysis-at-the-nanoscale-using-the-ptir-technique
#16
Georg Ramer, Vladimir Aksyuk, Andrea Centrone
Photothermal induced resonance (PTIR), also known as AFM-IR, is a scanning probe technique that provides sample composition information with a lateral resolution down to 20 nm. Interest in PTIR stems from its ability to identify unknown samples at the nanoscale thanks, in first approximation, to the direct comparability of PTIR spectra with far-field infrared databases. The development of rapidly tuning quantum cascade lasers has increased the PTIR throughput considerably, making nanoscale hyper-spectral imaging within a reasonable timeframe possible...
November 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29155564/mass-spectrometry-imaging-a-review-of-emerging-advancements-and-future-insights
#17
Amanda R Buchberger, Kellen DeLaney, Jillian Johnson, Lingjun Li
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations into the spatial distribution of molecular species in a variety of samples. It has the capability to image thousands of molecules, such as metabolites, lipids, peptides, proteins, and glycans, in a single experiment without labeling. The combination of information gained from mass spectrometry (MS) and visualization of spatial distributions in thin sample sections makes this a valuable chemical analysis tool useful for biological specimen characterization...
November 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29153255/-management-of-hypopigmented-scars-following-burn-injuries
#18
M Schmidt, K Serror, M Chaouat, M Mimoun, D Boccara
OBJECTIVE: Permanent hypopigmentation of burn scars is a common consequence after partial and full thickness burns that heal by secondary intent, and they can cause severe aesthetic issues. The surgical goals for effective treatment of postburn hypopigmentation are to remove scar tissues, and to produce healthy melanocytes, with minimal donor site morbidity. This article reviews the current literature about the different ways to treat hypopigmentation following burn injuries and discusses the indications...
November 15, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29152808/observational-safety-study-of-specific-outcomes-after-trivalent-cell-culture-seasonal-influenza-vaccination-optaflu-%C3%A2-among-adults-in-thin-database-of-electronic-uk-primary-healthcare-records
#19
Gillian C Hall, Paul T G Davies, M Yousuf Karim, Mendel D M Haag, Caroline O'Leary
PURPOSE: To investigate the safety of trivalent seasonal influenza vaccine (TIVc) (Optaflu(®) ), the first cell culture seasonal trivalent influenza vaccine available in Europe. METHODS: Codes and unstructured text in adult electronic healthcare records (The Health Improvement Network) were searched for a TIVc brand name or batch number and possible outcomes within a 3 month pre- to 6 month post-TIVc exposure study period (2012-2015). The outcomes were severe allergic reactions, Bell's palsy, convulsions, demyelination, paresthesia, noninfectious encephalitis, neuritis (optic and brachial), vasculitis, inflammatory bowel disease, and thrombocytopenia...
November 20, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29134723/the-ct-defined-hyperdense-arterial-sign-as-a-marker-for-acute-intracerebral-large-vessel-occlusion
#20
Jaims Lim, Jordan A Magarik, Michael T Froehler
BACKGROUND AND PURPOSE: To determine the sensitivity and specificity of the hyperdense artery sign (HAS) on thin-slice non-contrast computed tomography (NCCT), combined with brief clinical history, as an indicator for large vessel occlusion (LVO) in the setting of acute ischemic stroke. METHODS: Ninety-nine LVO and 102 non-LVO acute ischemic stroke patients were retrospectively identified from a prospective database at a single institution. After reviewing each patient's neurologic presentation based on his or her initial National Institute of Health Stroke Scale (NIHSS) and neurologic evaluation, all thin (1 mm) and thick (5 mm) NCCT scans were reviewed for the HAS...
November 14, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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