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https://www.readbyqxmd.com/read/29784964/high-speed-photothermal-off-resonance-atomic-force-microscopy-reveals-assembly-routes-of-centriolar-scaffold-protein-sas-6
#1
Adrian P Nievergelt, Niccolò Banterle, Santiago H Andany, Pierre Gönczy, Georg E Fantner
The self-assembly of protein complexes is at the core of many fundamental biological processes 1 , ranging from the polymerization of cytoskeletal elements, such as microtubules 2 , to viral capsid formation and organelle assembly 3 . To reach a comprehensive understanding of the underlying mechanisms of self-assembly, high spatial and temporal resolutions must be attained. This is complicated by the need to not interfere with the reaction during the measurement. As self-assemblies are often governed by weak interactions, they are especially difficult to monitor with high-speed atomic force microscopy (HS-AFM) due to the non-negligible tip-sample interaction forces involved in current methods...
May 21, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29783968/investigating-porcine-parvoviruses-genogroup-2-infection-using-in-situ-polymerase-chain-reaction
#2
Dinko Novosel, Daniel Cadar, Tamás Tuboly, Andreja Jungic, Tomasz Stadejek, Tahar Ait-Ali, Attila Cságola
BACKGROUND: Porcine parvovirus 2 (PPV2) was detected in swine serum without showing any relationship with disease. The emergence of the virus seemed to be a unique event until other genetically highly similar parvoviruses were identified in China and, later in 2012, the presence of the virus was also described in Europe. PPV2 is widely distributed in pig populations where it is suspected to be involved in respiratory conditions, based on its frequent detection in lung samples. In order to investigate the potential pathogenic involvement of PPV2, 60 dead pigs were examined from two farms...
May 21, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29783656/aging-resistant-functionalized-ldh%C3%A2-sas-nitrile-butadiene-rubber-composites-preparation-and-study-of-aging-kinetics-anti-aging-mechanism
#3
Tianxiang Li, Zhengren Shi, Xianru He, Ping Jiang, Xiaobin Lu, Rui Zhang, Xin Wang
With the aim of improving the anti-aging properties of nitrile-butadiene rubber (NBR), a functional organic filler, namely LDH⁻SAS, prepared by intercalating 4-amino-benzenesulfonic acid monosodium salt (SAS) into layered double hydroxides (LDHs) through anion exchange, was added to nitrile-butadiene rubber (NBR), giving the NBR/LDH⁻SAS composites. Successful preparation of LDH⁻SAS was confirmed by XRD, TGA and FTIR. LDH⁻SAS was well dispersed in the NBR matrix, owing to its strong interaction with the nitrile group of NBR...
May 18, 2018: Materials
https://www.readbyqxmd.com/read/29783029/comparison-of-stanford-b-aortic-dissection-patients-who-received-tevar-combined-with-or-without-sleep-apnea-syndrome
#4
Xin Li, Wenwu Cai, Ping Zhang, Kun Fang, Jieting Zhu, Chang Shu
BACKGROUND: Patients with Stanford B aortic dissection usually complicated with sleep apnea syndrome. This condition always threatens the patients' respiration situation. In this study, we collected and analysis data of patients' peri-operative managements of Thoracic Endovascular Aortic Repair (TEVAR) for Stanford B Aortic Dissection (AD) complicated with Sleep Apnea Syndrome (SAS). Comparison has been made between these SAS patients and those who without SAS. METHODS: Between June 2013 and June 2014, the clinical data and outcomes of the Stanford B AD patients in the department of vascular surgery in the Second Xiangya Hospital were retrospectively reviewed and studied...
May 18, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29780733/the-effect-of-expiration-date-on-mechanical-properties-of-resin-composites
#5
Joseph Sabbagh, Fidele Nabbout, Edgard Jabbour, Gaetane Leloup
Objective: The aim of this in vitro study is to evaluate the effect of expiration date on some mechanical properties of resin composites after controlled storage of syringes and compules in a refrigerator at 4°C. Materials and Methods: Specimens were tested at 7 days after storage in distilled water at room temperature. The investigated properties are the static modulus of elasticity, the flexural strength, and the Vickers microhardness. Same batches of restorative materials were examined at baseline (at least 1 year before their expiration date) and 1 year after they expired...
March 2018: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29778467/short-communication-effect-of-abomasal-inorganic-phosphorus-infusion-on-phosphorus-absorption-in-large-intestine-milk-production-and-phosphorus-excretion-of-dairy-cattle
#6
X Feng, P P Ray, J P Jarrett, L Karpinski, B Jones, K F Knowlton
The objective of the study was to evaluate the effect of inorganic phosphorus (Pi) infusion on P absorption in large intestine, milk production, and phosphorus excretion. Four ruminally and ileally cannulated crossbred cows were used in a 4 × 4 Latin square with 21-d periods. Cows were fed a total mixed ration containing 0.21% P, providing 50% of the cows' P requirement. Cobalt-EDTA was used as marker to measure large intestine digesta flow. On d 13 to 21 of each period, each cow was infused daily with 0, 20...
May 16, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29777770/construction-and-feasibility-study-of-the-sofmer-activity-score-sas-a-new-assessment-of-physical-and-cognitive-activity
#7
M D Morard, S Gonzalez-Monge, P Rippert, S Roche, J C Bernard, D Lagauche, C Delvert, J Luauté, S Jacquin Courtois, F Caillet, J Di Marco, F Ghelfi, S Otmani, P Calmels, M Royet, P A Joseph, R Ecochard, G Rode, C Vuillerot
OBJECTIVES: For hospitalizations in rehabilitation centers (RCs) in France, the quantification of healthcare givers' activity is based on the dependency of the patients, defined as a total or partial inability to perform activities required for daily living without help. The tools currently used to quantify dependency are not sufficiently precise. Here we describe the construction of a new tool, the SOFMER Activity Score (SAS scoring), which allows for a good description of the level of activity of patients hospitalized in RCs, and a feasibility study of the tool...
May 16, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29776836/analysis-of-incidence-of-traumatic-brain-injury-in-blunt-trauma-patients-with-glasgow-coma-scale-of-12-or-less
#8
Alexander Becker, Kobi Peleg, Oded Olsha, Adi Givon, Boris Kessel
PURPOSE: Early diagnosis of traumatic brain injury (TBI) is important for improving survival and neurologic outcome in trauma victims. The purpose of this study was to assess whether Glasgow Coma Scale (GCS) of 12 or less can predict the presence of TBI and the severity of associated injuries in blunt trauma patients. METHODS: A retrospective cohort study including 303,435 blunt trauma patients who were transferred from the scene to hospital from 1998 to 2013. The data was obtained from the records of the National Trauma Registry maintained by Israel's National Center for Trauma and Emergency Medicine Research, in the Gertner Institute for Epidemiology and Health Policy Research...
April 16, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29776420/the-relationship-between-preoperative-psychological-evaluation-and-compensatory-sweating
#9
Huai-Yu Wang, Yan-Jun Zhu, Jie Liu, Li-Wei Li, Ying-Hui Liu
BACKGROUND: This study analyzes the relationship between preoperative psychological states of primary palmar hyperhidrosis patients and postoperative compensatory sweating. METHODS: We evaluated the psychological states of patients with primary palmar hyperhidrosis who received sympathectomy in our hospital from 2016 to 2017. The relationship between preoperative psychological states and postoperative compensatory sweating were assessed using Spearman's rank-order correlation...
May 18, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29776008/factors-associated-with-self-reported-history-of-depression-diagnosis-among-cancer-survivors-aged-18-years-and-over-in-the-united-states
#10
Gemechu B Gerbi, Stranjae' Ivory, Elaine Archie Booker, Mechelle D Claridy, Stephanie Miles-Richardson
OBJECTIVE: According to the American Cancer Society, 25 percent of cancer survivors in the United States develop depression. The objective of this study is to assess factors associated with self-reported history of depression diagnosis among cancer survivors aged ≥18 years in the United States. METHODS: Data were analyzed from the 2014 Behavioral Risk Factor Surveillance System (BRFSS) (N=6,079). The BRFSS collects data about US residents regarding their health-related risk behaviors and events, chronic health conditions, and use of preventive services...
May 18, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29775435/national-center-for-health-statistics-guidelines-for-analysis-of-trends
#11
Deborah D Ingram, Donald J Malec, Diane M Makuc, Deanna Kruszon-Moran, Renee M Gindi, Michael Albert, Vladislav Beresovsky, Brady E Hamilton, Julia Holmes, Jeannine Schiller, Manisha Sengupta
Many reports present analyses of trends over time based on multiple years of data from National Center for Health Statistics (NCHS) surveys and the National Vital Statistics System (NVSS). Trend analyses of NCHS data involve analytic choices that can lead to different conclusions about the trends. This report discusses issues that should be considered when conducting a time trend analysis using NCHS data and presents guidelines for making trend analysis choices. Trend analysis issues discussed include: choosing the observed time points to include in the analysis, considerations for survey data and vital records data (record level and aggregated), a general approach for conducting trend analyses, assorted other analytic issues, and joinpoint regression...
April 2018: Vital and Health Statistics. Series 2, Data Evaluation and Methods Research
https://www.readbyqxmd.com/read/29771077/-observation-of-flupentixol-and-melitracen-on-curative-effect-of-sudden-deafness-patients-with-anxiety-and-depression-in-different-stages
#12
T Zhang, G D Yu
Objective: To investigate the efficacy of flupentixol melitracen on different stages of sudden deafness patients with anxiety and depression. Method: Totally one hundred and sixty-three sudden deafness patients with anxiety and depression were randomly divided into two groups: experimental group(81 cases) and control group (82 cases). All patients were given routine treatment for 2 weeks. The experimental group was given oral flupentixol melitracen (1 tablet/day)for a period of 3 months. The hearing, tinnitus effect and vertigo treatment course were observed and compared...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29769243/hospitalization-for-suicide-ideation-or-attempt-2008-2015
#13
Gregory Plemmons, Matthew Hall, Stephanie Doupnik, James Gay, Charlotte Brown, Whitney Browning, Robert Casey, Katherine Freundlich, David P Johnson, Carrie Lind, Kris Rehm, Susan Thomas, Derek Williams
OBJECTIVES: Suicide ideation (SI) and suicide attempts (SAs) have been reported as increasing among US children over the last decade. We examined trends in emergency and inpatient encounters for SI and SA at US children's hospitals from 2008 to 2015. METHODS: We used retrospective analysis of administrative billing data from the Pediatric Health Information System database. RESULTS: There were 115 856 SI and SA encounters during the study period...
May 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29765938/utilizing-benzotriazole-and-indacenodithiophene-units-to-construct-both-polymeric-donor-and-small-molecular-acceptors-to-realize-organic-solar-cells-with-high-open-circuit-voltages-beyond-1-2-v
#14
Ailing Tang, Fan Chen, Bo Xiao, Jing Yang, Jianfeng Li, Xiaochen Wang, Erjun Zhou
Devolopment of organic solar cells with high open-circuit voltage ( V OC ) and power conversion efficiency (PCE) simutaniously plays a significant role, but there is no guideline how to choose the suitable photovoltaic material combinations. In our previous work, we developed "the Same-Acceptor-Strategy" (SAS), by utilizing the same electron-accepting segment to construct both polymeric donor and small molecular acceptor. In this study, we further expend SAS to use both the same electron-accepting and electron-donating units to design the material combination...
2018: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29765534/bi2536-induces-mitotic-catastrophe-and-radiosensitization-in-human-oral-cancer-cells
#15
Chieh-Yuan Cheng, Chung-Ji Liu, Yu-Chuen Huang, Shu-Hua Wu, Hsu-Wei Fang, Yu-Jen Chen
BI2536 has been developed as a potential therapeutic agent for various cancers but not in oral cancer cells. Since BI2536 exhibits mitosis-regulating activity which are the most radiosensitive, we hypothesized that BI2536 might modulate the radiosensitivity of oral cancer cells. Human normal fibroblasts, oral cancer SAS, and OECM1 cells were treated with BI2536 (0-50 nM) and/or radiation (0-4 Gy). MTT assay, Liu's staining, flow cytometry, clonogenic assay, Annexin V/propidium iodide (PI) staining, western blot analysis, and small interfering RNA knockdown experiments were used to assess cell viability, morphology, cell cycle progression, radiation survival, and expression of regulatory proteins in vitro ...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29764907/mortality-in-acromegaly-decreased-in-the-last-decade-a-systematic-review-and-meta-analysis
#16
Fernanda Bolfi, Adriele Ferreira Neves, Cesar Luiz Boguszewski, Vania Santos Nunes-Nogueira
OBJECTIVE: To compare the acromegaly mortality rates with those expected for the general population from studies published before and after 2008. METHODS: We performed a systematic review and included observational studies in which the number of deaths observed in acromegaly was compared with the expected mortality for the general population (O/E). The following electronic databases were used as our data sources: Embase, Medline and Lilacs. From the O/E, we recalculated all Standardized Mortality Rates (SMR), and their respective confidence intervals (95% CI) which were plotted in a meta-analysis using the software RevMan 5...
May 15, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29764436/prevalence-and-incidence-of-complications-at-diagnosis-of-t2dm-and-during-follow-up-by-bmi-and-ethnicity-a-matched-case-control-analysis
#17
Ebenezer S Owusu Adjah, Srikanth Bellary, Wasim Hanif, Kiran Patel, Kamlesh Khunti, Sanjoy K Paul
AIMS: To estimate the risk of developing long-term major cardiovascular and renal complications in relation to levels of body mass index (BMI) in a population of White European (WE), African-Caribbean (AC), and South Asian (SA) patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: Patients with new diagnosis of T2DM, aged ≥ 18 years from January 2000 (n = 69,436) and their age-sex-ethnicity matched non-diabetic controls (n = 272,190) were identified from UK primary care database...
May 15, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29763785/exposure-to-progesterone-previous-to-the-protocol-of-ovulation-synchronization-increases-the-follicular-diameter-and-the-fertility-of-suckled-bos-indicus-cows
#18
L M S Simões, R E Orlandi, J P M Massoneto, L A Scandiuzzi, B G Freitas, M R Bastos, J C Souza, J N S Sales
The objective was to evaluate the effect of injectable progesterone previous to the timed artificial insemination (TAI) protocol on follicular growth, ovulation and pregnancy rate of suckled Bos indicus cows. In experiment 1, 10 days before the beginning to TAI protocol (D-10), 431 suckled-anestrus Nelore cows (249 multiparous and 182 primiparous), were allocated to one of three treatments groups (control, P4i and P4iGnRH). At this moment, cows in the P4i and P4iGnRH group received 150 mg of injectable progesterone intramuscularly (Sincrogest injetável® , Ouro Fino, Brazil)...
May 3, 2018: Theriogenology
https://www.readbyqxmd.com/read/29763515/individualized-breathlessness-interventions-may-improve-outcomes-in-patients-with-advanced-copd
#19
Mary Y Y Qian, John Politis, Michelle Thompson, Darren Wong, Brian Le, Louis Irving, Natasha Smallwood
BACKGROUND AND OBJECTIVE: Many patients with advanced COPD experience refractory breathlessness and individualized breathlessness interventions may improve management of this complex symptom. The aims of this study were to develop, implement and assess the efficacy of a breathlessness intervention for patients with COPD and refractory breathlessness and to evaluate patient acceptability. METHODS: An individualized breathlessness plan, information leaflets, breathlessness education and a hand-held fan were offered to consecutive patients with severe COPD and refractory breathlessness attending a tertiary integrated respiratory and palliative care service...
May 15, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29762778/the-effect-of-%C3%AE-mannanase-on-nutrient-utilization-and-blood-parameters-in-chicks-fed-diets-containing-soybean-meal-and-guar-gum
#20
Justina V Caldas, Karen Vignale, Nirun Boonsinchai, Jinrong Wang, Monticha Putsakum, Judith A England, Craig N Coon
The present study was conducted to determine whether the addition of β-mannanase in broiler feed changes hormonal profiles in the blood and broiler performance and nutrient availability. Five hundred and four Cobb male chickens were studied during d 7 to 21. Three corn-soybean meal (SBM) based diets 1) Low SBM (18% SBM); 2) High SBM (31% SBM); and 3) High SBM+GG (31% SBM + Guar Gum (GG) 0.5%) with 3 levels of β-mannanase (0, 200, and 400 ppm) were mixed to produce 9 diets. A factorial design 3 × 3 was performed with JMP pro 13 (SAS, 2017)...
May 11, 2018: Poultry Science
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