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https://www.readbyqxmd.com/read/27922916/longitudinal-trends-in-anxiety-depression-and-quality-of-life-during-different-intermittent-periods-of-adjuvant-breast-cancer-chemotherapy
#1
Zhang Jiayuan, Zhou Yuqiu, Feng Ziwei, Xu Yong, Zeng Guangchun
BACKGROUND: Chemotherapy (CT) is an important adjuvant treatment that has been widely used for breast cancer (BC) patients. However, no research has focused on trends in emotions and quality of life (QOL) during intermittent periods between CT sessions that are critical for recovery. OBJECTIVE: The aim of this study was to investigate longitudinal trends in anxiety, depression, and QOL during the different intermittent periods between adjuvant CT for BC. METHODS: A longitudinal study design was adopted...
December 5, 2016: Cancer Nursing
https://www.readbyqxmd.com/read/27922811/the-number-of-recalled-leads-is-highly-predictive-of-lead-failure-results-from-the-pacemaker-and-implantable-defibrillator-leads-survival-study-paidless
#2
Daniel J Kersten, Jinju Yi, Alyssa M Feldman, Kunal Brahmbhatt, Wilbur J Asheld, Joseph Germano, Shahidul Islam, Todd J Cohen
OBJECTIVES: The purpose of this study was to determine if implantation of multiple recalled defibrillator leads is associated with an increased risk of lead failure. BACKGROUND: The authors of the Pacemaker and Implantable Defibrillator Leads Survival Study ("PAIDLESS") have previously reported a relationship between recalled lead status, lead failure, and patient mortality. This substudy analyzes the relationship in a smaller subset of patients who received more than one recalled lead...
December 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27920722/a-new-structure-activity-relationship-sar-model-for-predicting-drug-induced-liver-injury-based-on-statistical-and-expert-based-structural-alerts
#3
Fabiola Pizzo, Anna Lombardo, Alberto Manganaro, Emilio Benfenati
The prompt identification of chemical molecules with potential effects on liver may help in drug discovery and in raising the levels of protection for human health. Besides in vitro approaches, computational methods in toxicology are drawing attention. We built a structure-activity relationship (SAR) model for evaluating hepatotoxicity. After compiling a data set of 950 compounds using data from the literature, we randomly split it into training (80%) and test sets (20%). We also compiled an external validation set (101 compounds) for evaluating the performance of the model...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27920475/impact-of-frailty-on-approach-to-colonic-resection-laparoscopy-vs-open-surgery
#4
Catalina Mosquera, Konstantinos Spaniolas, Timothy L Fitzgerald
AIM: To understand the influence of frailty on postoperative outcomes for laparoscopic and open colectomy. METHODS: Data were obtained from the National Surgical Quality Improvement Program (2005-2012) for patients undergoing colon resection [open colectomy (OC) and laparoscopic colectomy (LC)]. Patients were classified as non-frail (0 points), low frailty (1 point), moderate frailty (2 points), and severe frailty (≥ 3) using the Modified Frailty Index. 30-d mortality and complications were used as the primary end point and analyzed for the overall population...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27918351/pediatric-oncology-discharges-with-febrile-neutropenia-variation-in-location-of-care
#5
Elysia Alvarez, Lisa J Chamberlain, Catherine Aftandilian, Olga Saynina, Paul Wise
We examined the use of Pediatric Cancer Specialty Centers (PCSCs) over time and the length of stay (LOS) in pediatric oncology patients with a diagnosis of febrile neutropenia. PCSCs were defined as Children's Oncology Group and California Children's Services designated centers. We performed a retrospective analysis on all discharges of pediatric (0 to 18) oncology patients with febrile neutropenia in California (1983 to 2011) using the private Office of Statewide Health Planning and Development database. We examined influence of age, sex, race/ethnicity, payer, income, distance, tumor type, and complications on utilization of PCSCs and LOS (SAS 9...
December 1, 2016: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27917483/it-takes-a-village-promoting-parent-and-family-education-on-healthy-lifestyles-for-minnesota-secondary-students
#6
Mary O Hearst, Qi Wang, Katherine Grannon, Cynthia S Davey, Marilyn S Nanney
BACKGROUND: This study examines school strategies to educate parents over time about physical activity and nutrition and how those strategies are related to adolescent health behaviors. METHODS: Data from the Minnesota School Health Profiles Lead Health Education Teacher survey (2008-2012) and the Minnesota Student Survey (MSS, 2013) included provisions for parent education about physical activity and nutrition and student physical activity and dietary intake behaviors...
January 2017: Journal of School Health
https://www.readbyqxmd.com/read/27916528/repeated-inactivation-of-the-first-committed-enzyme-underlies-the-loss-of-benzaldehyde-emission-after-the-selfing-transition-in-capsella
#7
Claudia Sas, Frank Müller, Christian Kappel, Tyler V Kent, Stephen I Wright, Monika Hilker, Michael Lenhard
The enormous species richness of flowering plants is at least partly due to floral diversification driven by interactions between plants and their animal pollinators [1, 2]. Specific pollinator attraction relies on visual and olfactory floral cues [3-5]; floral scent can not only attract pollinators but also attract or repel herbivorous insects [6-8]. However, despite its central role for plant-animal interactions, the genetic control of floral scent production and its evolutionary modification remain incompletely understood [9-13]...
November 23, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27914517/effect-of-flaxseed-oil-and-microalgae-dha-on-the-production-performance-fatty-acids-and-total-lipids-of-egg-yolk-and-plasma-in-laying-hens
#8
M Neijat, O Ojekudo, J D House
The incorporation of omega-3 polyunsaturated fatty acids (PUFA) in the egg is dependent on both the transfer efficiency of preformed dietary omega-3 fatty acids to the eggs as well as endogenous PUFA metabolism and deposition. Employing an experimental design consisting of 70 Lohmann LSL-Classic hens (n=10/treatment) in a 6-week feeding trial, we examined the impact of graded levels of either flaxseed oil (alpha-linolenic acid, ALA) or algal DHA (preformed docosahexaenoic acid, DHA), each supplying 0.20%, 0...
December 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27913041/impact-of-lymph-node-evaluation-in-adjuvant-and-neoadjuvant-chemotherapy-settings-on-survival-outcomes-in-wilms-tumour-a-review-of-185-cases-from-a-single-institution
#9
Ronica H Nanda, Bahig M Shehata, Nasim Khoshnam, Megan Durham, Sungjin Kim, Wasim Selwanes, Zhengjia Chen, Chao Zhang, Natia Esiashvili
It is unclear if lymph node sampling in Wilms tumour, though critical for staging purposes, affects survival outcomes. The value of lymph node sampling in patients treated with neoadjuvant chemotherapy (NAC) is even more uncertain. We reviewed our institutional data to determine the impact of lymph node sampling on survival, as well as its role in the context of NAC. A total of 185 patients with Wilms tumour treated at our institution were included in this analysis. The number of nodes sampled (≤7, or >7), lymph node status (unknown, negative, or positive), pathological stage, and use of neoadjuvant chemotherapy were analysed for survival outcomes...
November 29, 2016: Pathology
https://www.readbyqxmd.com/read/27911923/morphology-and-hydraulic-architecture-of-vitis-vinifera-l-cv-syrah-and-torront%C3%A3-s-riojano-plants-are-unaffected-by-variations-in-red-to-far-red-ratio
#10
Carina Verónica González, María Florencia Jofré, Hernán F Vila, Markus Stoffel, Rubén Bottini, Carla Valeria Giordano
Plants have evolved an array of specific photoreceptors to acclimate to the light environment. By sensing light signals, photoreceptors modulate plant morphology, carbon- and water-physiology, crop yield and quality of harvestable organs, among other responses. Many cultural practices and crop management decisions alter light quantity and quality perceived by plants cultivated in the field. Under full sunlight, phytochromes perceive high red to far red ratios (R:FR; 1.1), whereas overhead or lateral low R:FR (below 1...
2016: PloS One
https://www.readbyqxmd.com/read/27911707/the-plk4-stil-sas-6-module-at-the-core-of-centriole-duplication
#11
REVIEW
Christian Arquint, Erich A Nigg
Centrioles are microtubule-based core components of centrosomes and cilia. They are duplicated exactly once during S-phase progression. Central to formation of each new (daughter) centriole is the formation of a nine-fold symmetrical cartwheel structure onto which microtubule triplets are deposited. In recent years, a module comprising the protein kinase polo-like kinase 4 (PLK4) and the two proteins STIL and SAS-6 have been shown to stay at the core of centriole duplication. Depletion of any one of these three proteins blocks centriole duplication and, conversely, overexpression causes centriole amplification...
October 15, 2016: Biochemical Society Transactions
https://www.readbyqxmd.com/read/27910449/a-stabilized-laser-continuously-tunable-over-a-range-of-1-5-ghz
#12
B L Fan, W Xiong, S G Wang, L J Wang
We demonstrate a method to stabilize laser frequency which can be continuously tuned over a range of 1.5 GHz. It is based on saturated absorption spectroscopy (SAS) generated by an external-cavity diode laser (ECDL) which is modulated by an electro-optic amplitude modulator (EO-AM). The spectra consist of not only the original peaks corresponding to resonant and crossover lines of (133)Cs D2 line, but also signals introduced by sidebands from an EO-AM. Thus, the laser frequency can be locked to any point within the range of the spectra...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27909384/examining-emotional-support-animals-and-role-conflicts-in-professional-psychology
#13
Jeffrey N Younggren, Jennifer A Boisvert, Cassandra L Boness
This article examines the role conflicts that psychologists may face in their practices related to the evaluation and certification of emotional support animals (ESAs). It reviews the legal differences between ESAs and service animals (SAs), outlines ethical guidelines and legal policies/regulations regarding the use of ESAs, and examines the potential role conflicts that exist when a treating psychologist is certifying the need for an ESA. Finally, it makes recommendations to assist psychologists in staying within the standards of practice in order to avoid the ethical and legal risks associated with certifying an ESA...
August 2016: Professional Psychology, Research and Practice
https://www.readbyqxmd.com/read/27908212/are-crh-ngf-as-psychoneuroimmune-regulators-in-women-with-polycystic-ovary-syndrome
#14
F Z Zangeneh, M M Naghizadeh, M Bagheri, M Jafarabadi
PURPOSE: Polycystic ovary syndrome (PCOS) affects quality of life and can worsen anxiety and depression either due to the features of PCOS or due to the diagnosis of a chronic disease. Corticotrophin-releasing hormone (CRH) and nerves growth factor (NGF) are the modulator for the actions of the sympathetic nervous and immune systems. METHODS: In total, 171 women divided into two groups: study and control groups. Serum CRH, NGF, and interleukins: IL-1α. IL-1β, 17A, and TNFα were determined by ELISA Kits in both groups...
December 2, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27908169/flexible-mini-gamma-camera-reconstructions-of-extended-sources-using-step-and-shoot-and-list-mode
#15
José Gardiazabal, Philipp Matthies, Jakob Vogel, Benjamin Frisch, Nassir Navab, Sibylle Ziegler, Tobias Lasser
PURPOSE: Hand- and robot-guided mini gamma cameras have been introduced for the acquisition of single-photon emission computed tomography (SPECT) images. Less cumbersome than whole-body scanners, they allow for a fast acquisition of the radioactivity distribution, for example, to differentiate cancerous from hormonally hyperactive lesions inside the thyroid. This work compares acquisition protocols and reconstruction algorithms in an attempt to identify the most suitable approach for fast acquisition and efficient image reconstruction, suitable for localization of extended sources, such as lesions inside the thyroid...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27907923/association-between-the-surgical-apgar-score-and-perioperative-complications-after-radical-prostatectomy
#16
Matthias Orberger, Jüri Palisaar, Florian Roghmann, Ludger Mittelstädt, Petra Bischoff, Joachim Noldus, Björn Löppenberg
OBJECTIVE: To evaluate whether the Surgical Apgar Score (SAS) can identify patients who are at risk for perioperative adverse events (PAE) following radical prostatectomy for prostate cancer. PATIENTS AND METHODS: At a single academic institution, 994 patients undergoing radical prostatectomy between 2010 and 2013 were analyzed retrospectively. The SAS was calculated from anesthesia records, evaluated to predict PAE within a 30-day time period postoperatively; these events were classified according to standardized classification systems...
December 2, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27907828/surgical-apgar-score-in-patients-undergoing-lumbar-fusion-for-degenerative-spine-diseases
#17
Chien-Yu Ou, Shih-Yuan Hsu, Jian-Hao Huang, Yu-Hua Huang
OBJECTIVE: Lumbar fusion is a procedure broadly performed for degenerative diseases of spines, but it is not without significant morbidities. Surgical Apgar Score (SAS), based on intraoperative blood loss, blood pressure, and heart rate, was developed for prognostic prediction in general and vascular operations. We aimed to examine whether the application of SAS in patients undergoing fusion procedures for degeneration of lumbar spines predicts in-hospital major complications. METHODS: One hundred and ninety-nine patients that underwent lumbar fusion operation for spine degeneration were enrolled in this retrospective study...
November 21, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27907089/detection-of-human-papillomavirus-infection-in-patients-with-vaginal-intraepithelial-neoplasia
#18
Cristina Lamos, Charlotte Mihaljevic, Sebastian Aulmann, Thomas Bruckner, Christoph Domschke, Markus Wallwiener, Carmen Paringer, Herbert Fluhr, Sarah Schott, Christine Dinkic, Janina Brucker, Michael Golatta, Lisa Gensthaler, Michael Eichbaum, Christof Sohn, Joachim Rom
INTRODUCTION: Vaginal intraepithelial neoplasia (VAIN) is a pre-malignant lesion, potentially leading to vaginal cancer. It is a rare disease, representing less than 1% of all intraepithelial neoplasia of the female genital tract. Similar to cervical intraepithelial neoplasia (CIN), there are three different grades of VAIN. VAIN 1 is also known as a low-grade squamous intraepithelial lesion (LSIL), whereas VAIN 2 and VAIN 3 both represent high-grade squamous intraepithelial lesions (HSIL)...
2016: PloS One
https://www.readbyqxmd.com/read/27905988/a-population-study-on-the-time-trend-of-cigarette-smoking-cessation-and-exposure-to-secondhand-smoking-from-2001-to-2013-in-taiwan
#19
Chi-Yung Chiang, Hsing-Yi Chang
BACKGROUND: In 2001, the National Health Interview Survey (NHIS) commenced in Taiwan. This survey, conducted on a sample of the whole Taiwanese population, is nationally representative and has a high response rate (>80 %). As a result, the four already completed surveys from 2001 to 2013 can be used to investigate the time trend of smoking prevalence, the rate of cessation, and exposure to secondhand smoking. METHODS: There were 72918 adults combined from the 2001, 2005, 2009 and 2013 National Health Interview Surveys (NHIS)...
November 5, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27904534/metaplastic-breast-cancer-with-rapidly-progressive-recurrence-in-a-young-woman-case-report-and-review-of-the-literature
#20
Jerzy W Mituś, Beata Sas-Korczyńska, Anna Kruczak, Marek Jasiówka, Janusz Ryś
No abstract text is available yet for this article.
December 1, 2016: Archives of Medical Science: AMS
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