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https://www.readbyqxmd.com/read/28528449/the-canadian-national-breast-screening-studies-are-compromised-and-their-results-are-unreliable-they-should-not-factor-into-decisions-about-breast-cancer-screening
#1
REVIEW
Daniel B Kopans
The Canadian National Breast Screening Studies were compromised by an unblinded allocation process and poor quality mammography. Contrary to the requirement that allocation in a randomized controlled trial (RCT) be blinded to avoid any possible intentional or unintentional subversion of a random allocation, all women in the CNBSS trials underwent a clinical breast examination prior to assignment to the study arm or the usual care arm. Women with abnormal clinical breast examinations were identified, and this information was available to the coordinators who then assigned the women on open lists...
May 20, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28515192/study-protocol-for-a-transversal-study-to-develop-a-screening-model-for-excessive-gambling-behaviours-on-a-representative-sample-of-users-of-french-authorised-gambling-websites
#2
Bastien Perrot, Jean-Benoit Hardouin, Jean-Michel Costes, Julie Caillon, Marie Grall-Bronnec, Gaëlle Challet-Bouju
INTRODUCTION: Since the legalisation of online gambling in France in 2010, gambling operators must implement responsible gambling measures to prevent excessive gambling practices. However, actually there is no screening procedure for identifying problematic gamblers. Although several studies have already been performed using several data sets from online gambling operators, the authors deplored several methodological and clinical limits that prevent scientifically validating the existence of problematic gambling behaviour...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28499282/can-social-network-analysis-help-address-the-high-rates-of-bacterial-sexually-transmitted-infections-in-saskatchewan
#3
Molly A Trecker, Jo-Anne R Dillon, Kathy Lloyd, Maurice Hennink, Ann Jolly, Cheryl Waldner
BACKGROUND: Saskatchewan has one of the highest rates of gonorrhea among the Canadian provinces-more than double the national rate. In light of these high rates, and the growing threat of untreatable infections, improved understanding of gonorrhea transmission dynamics in the province and evaluation of the current system and tools for disease control are important. METHODS: We extracted data from a cross-sectional sample of laboratory-confirmed gonorrhea cases between 2003 and 2012 from the notifiable disease files of the Regina Qu'Appelle Health Region...
June 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28494011/changes-in-the-use-practitioner-based-complementary-and-alternative-medicine-over-time-in-canada-cohort-and-period-effects
#4
Mayilee Canizares, Sheilah Hogg-Johnson, Monique A M Gignac, Richard H Glazier, Elizabeth M Badley
BACKGROUND: The use of complementary and alternative medicine (CAM) is growing. However the factors contributing to changes over time and to birth cohort differences in CAM use are not well understood. SETTING: We used data from 10186 participants, who were aged 20-69 years at the first cycle of data collection in the longitudinal component of the Canadian National Population Health Survey (1994/95-2010/11). We examined chiropractic and other practitioner-based CAM use with a focus on five birth cohorts: pre-World War II (born 1925-1934); World War II (born 1935-1944); older baby boomers (born 1945-1954); younger baby boomers (born 1955-1964); and Gen Xers (born 1965-1974)...
2017: PloS One
https://www.readbyqxmd.com/read/28492517/first-nations-approaches-to-childhood-obesity-healthy-lifestyles-in-canada-compared-with-alternatives-for-alaska-native-communities
#5
Peter A de Schweinitz, Janet M Wojcicki
Alaska Native and American Indian children have among the highest prevalence of obesity in the United States. Canadian Aboriginal populations including First Nations also have high rates of obesity but obesity rates among children are noticeably lower. We highlight some of the important differences between American and Canadian approaches to healthy lifestyles and Aboriginal/Native health, including diet and physical activity, which may in part explain the differences in obesity prevalence. Specifically, the Canadian government provides a food subsidy program to bring perishable fruits and vegetable to remote, rural Canadian areas and secondly supports the use of traditional foods and harvesting/gathering through a number of government supported programs...
May 11, 2017: Children
https://www.readbyqxmd.com/read/28469428/using-electronic-medical-record-to-identify-patients-with-dyslipidemia-in-primary-care-settings-international-classification-of-disease-code-matters-from-one-region-to-a-national-database
#6
Justin Oake, Erfan Aref-Eshghi, Marshall Godwin, Kayla Collins, Kris Aubrey-Bassler, Pauline Duke, Masoud Mahdavian, Shabnam Asghari
OBJECTIVE: To assess the validity of the International Classification of Disease (ICD) codes for identifying patients with dyslipidemia in electronic medical record (EMR) data. METHODS: The EMRs of patients receiving primary care in St. John's, Newfoundland and Labrador (NL), Canada, were retrieved from the Canadian Primary Care Sentinel Surveillance Network database. International Classification of Disease codes were first compared with laboratory lipid data as an independent criterion standard, and next with a "comprehensive criterion standard," defined as any existence of abnormal lipid test, lipid-lowering medication record, or dyslipidemia ICD codes...
2017: Biomedical Informatics Insights
https://www.readbyqxmd.com/read/28454045/canadian-harm-reduction-policies-a-comparative-content-analysis-of-provincial-and-territorial-documents-2000-2015
#7
REVIEW
T Cameron Wild, Bernie Pauly, Lynne Belle-Isle, Walter Cavalieri, Richard Elliott, Carol Strike, Kenneth Tupper, Andrew Hathaway, Colleen Dell, Donald MacPherson, Caitlin Sinclair, Kamagaju Karekezi, Benjamin Tan, Elaine Hyshka
BACKGROUND: Access to harm reduction interventions among substance users across Canada is highly variable, and largely within the policy jurisdiction of the provinces and territories. This study systematically described variation in policy frameworks guiding harm reduction services among Canadian provinces and territories as part of the first national multimethod case study of harm reduction policy. METHODS: Systematic and purposive searches identified publicly-accessible policy texts guiding planning and organization of one or more of seven targeted harm reduction services: needle distribution, naloxone, supervised injection/consumption, low-threshold opioid substitution (or maintenance) treatment, buprenorphine/naloxone (suboxone), drug checking, and safer inhalation kits...
April 25, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28449670/ethics-of-health-research-with-prisoners-in-canada
#8
Diego S Silva, Flora I Matheson, James V Lavery
BACKGROUND: Despite the growing recognition for the need to improve the health of prisoners in Canada and the need for health research, there has been little discussion of the ethical issues with regards to health research with prisoners in Canada. The purpose of this paper is to encourage a national conversation about what it means to conduct ethically sound health research with prisoners given the current realities of the Canadian system. Lessons from the Canadian system could presumably apply in other jurisdictions...
April 27, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28440036/a-tale-of-two-countries-all-cause-mortality-among-people-living-with-hiv-and-receiving-combination-antiretroviral-therapy-in-the-uk-and-canada
#9
S Patterson, S Jose, H Samji, A Cescon, E Ding, J Zhu, J Anderson, A N Burchell, C Cooper, T Hill, M Hull, M B Klein, M Loutfy, F Martin, N Machouf, Jsg Montaner, M Nelson, J Raboud, S B Rourke, C Tsoukas, R S Hogg, C Sabin
OBJECTIVES: We sought to compare all-cause mortality of people living with HIV and accessing care in Canada and the UK. METHODS: Individuals from the Canadian Observational Cohort (CANOC) collaboration and UK Collaborative HIV Cohort (UK CHIC) study who were aged ≥ 18 years, had initiated antiretroviral therapy (ART) for the first time between 2000 and 2012 and who had acquired HIV through sexual transmission were included in the analysis. Cox regression was used to investigate the difference in mortality risk between the two cohort collaborations, accounting for loss to follow-up as a competing risk...
April 24, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28439355/using-the-entrustable-professional-activities-framework-in-the-assessment-of-procedural-skills
#10
Debra Pugh, Rodrigo B Cavalcanti, Samantha Halman, Irene W Y Ma, Maria Mylopoulos, David Shanks, Lynfa Stroud
BACKGROUND: The entrustable professional activity (EPA) framework has been identified as a useful approach to assessment in competency-based education. To apply an EPA framework for assessment, essential skills necessary for entrustment to occur must first be identified. OBJECTIVE: Using an EPA framework, our study sought to (1) define the essential skills required for entrustment for 7 bedside procedures expected of graduates of Canadian internal medicine (IM) residency programs, and (2) develop rubrics for the assessment of these procedural skills...
April 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28434855/health-care-use-before-a-first-demyelinating-event-suggestive-of-a-multiple-sclerosis-prodrome-a-matched-cohort-study
#11
José M A Wijnands, Elaine Kingwell, Feng Zhu, Yinshan Zhao, Tanja Högg, Karen Stadnyk, Okechukwu Ekuma, Xinya Lu, Charity Evans, John D Fisk, Ruth Ann Marrie, Helen Tremlett
BACKGROUND: Degenerative processes in neurodegenerative diseases can start years before clinical manifestation. We aimed to establish whether a multiple sclerosis prodromal period exists by examining patterns of health-care use before a first demyelinating event. METHODS: In this matched cohort study, we used data from linked health administrative and clinical databases from four Canadian provinces (British Columbia, Saskatchewan, Manitoba, and Nova Scotia) to compare hospital, physician, and prescription use data from people with multiple sclerosis and matched general population controls in the 5 years before the first demyelinating disease claim (health administrative index date) or clinically reported symptom onset (clinical index date)...
April 20, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28433383/screening-for-chronic-kidney-disease-in-canadian-indigenous-peoples-is-cost-effective
#12
Thomas W Ferguson, Navdeep Tangri, Zhi Tan, Matthew T James, Barry D A Lavallee, Caroline D Chartrand, Lorraine L McLeod, Allison B Dart, Claudio Rigatto, Paul V J Komenda
Canadian indigenous (First Nations) have rates of kidney failure that are 2- to 4-fold higher than the non-indigenous general Canadian population. As such, a strategy of targeted screening and treatment for CKD may be cost-effective in this population. Our objective was to assess the cost utility of screening and subsequent treatment for CKD in rural Canadian indigenous adults by both estimated glomerular filtration rate and the urine albumin-to-creatinine ratio. A decision analytic Markov model was constructed comparing the screening and treatment strategy to usual care...
April 19, 2017: Kidney International
https://www.readbyqxmd.com/read/28425894/trends-in-smoking-initiation-in-canada-does-non-inclusion-of-young-adults-in-tobacco-control-strategies-represent-a-missed-opportunity
#13
Thierry Gagné, Gerry Veenstra
OBJECTIVES: Young adults face high prevalence rates for smoking. Recent evidence suggests that many people initiate smoking during young adulthood, but little is currently known about trends in initiation rates for this age group. METHODS: We examined rates of initiation to first cigarette (FC) and daily smoking (DS) during youth (5-17 years) and young adulthood (18-25 years) using nationally representative data from the 2001, 2003, 2005, 2007, 2009, 2011 and 2013 cycles of the Canadian Community Health Survey...
April 20, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28422581/-straight-from-the-heavens-into-your-bucket-domestic-rainwater-harvesting-as-a-measure-to-improve-water-security-in-a-subarctic-indigenous-community
#14
Nicholas Mercer, Maura Hanrahan
BACKGROUND: Black Tickle-Domino is an extremely water-insecure remote Inuit community in the Canadian subarctic that lacks piped-water. Drinking water consumption in the community is less than a third of the Canadian national average. Water insecurity in the community contributes to adverse health, economic, and social effects and requires urgent action. OBJECTIVES: To test the ability of domestic rainwater harvesting (DRWH) for the first time in the subarctic with the goal of improving water access and use in the community...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28418431/body-burdens-sources-and-interrelations-of-selected-toxic-and-essential-elements-among-the-nine-cree-first-nations-of-eeyou-istchee-james-bay-region-of-northern-quebec-canada
#15
Evert Nieboer, Ian D Martin, Eric N Liberda, Eric Dewailly, Elizabeth Robinson, Leonard J S Tsuji
BACKGROUND: this article constitutes a report on the comprehensive Nituuchischaayihtitaau Aschii multi-community environment-and-health study conducted among the Cree peoples (Eeyouch) of northern Quebec, Canada. OBJECTIVES: to interpret observed concentrations of a suite of chemical elements in a multi-media biological monitoring study in terms of sources and predictors. METHODS: the concentrations of 5 essential and 6 toxic chemical elements were measured in whole blood, and/or in urine or hair by ICP-MS...
April 18, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28408767/prevalence-and-correlates-of-physical-dating-violence-among-north-american-indigenous-adolescents
#16
Dane S Hautala, Kelley J Sittner Hartshorn, Brian Armenta, Les Whitbeck
This study examined the lifetime prevalence of physical dating violence, including victimization, perpetration, and the overlap between the two (mutual violence) among a population sample of 551 reservation/reserve residing Indigenous (i.e., American Indian and Canadian First Nations) adolescents in the upper-Midwest of the United States and Canada. Potential correlates of four dating violence profiles (i.e., no dating violence, perpetration-only, victimization-only, and mutual violence) relevant to this population also were considered...
April 2017: Youth & Society
https://www.readbyqxmd.com/read/28406758/fasting-triglycerides-as-a-predictor-of-incident-diabetes-insulin-resistance-and-%C3%AE-cell-function-in-a-canadian-first-nation
#17
Natalie D Riediger, Kirsten Clark, Virginia Lukianchuk, Joanne Roulette, Sharon Bruce
BACKGROUND: Diabetes prevalence is substantially higher among Canadian First Nations populations than the non-First Nation population. Fasting serum triglycerides have been found to be an important predictor of incident diabetes among non-indigenous populations. However, there is a great need to understand diabetes progression within specific ethnic groups, particularly First Nations populations. OBJECTIVE: The purpose of this study was to test for an association between fasting serum triglycerides and incident diabetes, changes in insulin resistance and changes in β-cell function in a Manitoba First Nation cohort...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28401140/the-canadian-minimum-dataset-for-chronic-low-back-pain-research-a-cross-cultural-adaptation-of-the-national-institutes-of-health-task-force-research-standards
#18
Anaïs Lacasse, Jean-Sébastien Roy, Alexandre J Parent, Nioushah Noushi, Chúk Odenigbo, Gabrielle Pagé, Nicolas Beaudet, Manon Choinière, Laura S Stone, Mark A Ware
BACKGROUND: To better standardize clinical and epidemiological studies about the prevalence, risk factors, prognosis, impact and treatment of chronic low back pain, a minimum data set was developed by the National Institutes of Health (NIH) Task Force on Research Standards for Chronic Low Back Pain. The aim of the present study was to develop a culturally adapted questionnaire that could be used for chronic low back pain research among French-speaking populations in Canada. METHODS: The adaptation of the French Canadian version of the minimum data set was achieved according to guidelines for the cross-cultural adaptation of self-reported measures (double forward-backward translation, expert committee, pretest among 35 patients with pain in the low back region)...
January 2017: CMAJ Open
https://www.readbyqxmd.com/read/28372942/human-biomonitoring-reference-values-derived-for-persistent-organic-pollutants-in-blood-plasma-from-the-canadian-health-measures-survey-2007-2011
#19
Douglas A Haines, Cheryl Khoury, Gurusankar Saravanabhavan, Kate Werry, Mike Walker, Morie Malowany
Nationally representative human biomonitoring data on persistent organic pollutants (POPs) including organochlorine pesticides (OCs), polychlorinated biphenyls (PCBs) brominated flame retardants (BFRs) and perfluoroalkyl substances (PFASs) are available through the Canadian Health Measures Survey (CHMS). We have used a systematic approach building on the reference interval concept proposed by the International Federation of Clinical Chemistry and Laboratory Medicine and the International Union of Pure and Applied Chemistry to derive human biomonitoring reference values (RV95s) for selected POPs in blood plasma in the general Canadian population...
March 18, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28372467/the-2015-national-canadian-homeless-youth-survey-mental-health-and-addiction-findings
#20
Sean A Kidd, Stephen Gaetz, Bill O'Grady
OBJECTIVE: This study was designed to provide a representative description of the mental health of youth accessing homelessness services in Canada. It is the most extensive survey in this area to date and is intended to inform the development of mental health and addiction service and policy for this marginalized population. METHODS: This study reports mental health-related data from the 2015 "Leaving Home" national youth homelessness survey, which was administered through 57 agencies serving homeless youth in 42 communities across the country...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
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