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https://www.readbyqxmd.com/read/28331822/risk-assessment-in-relation-to-the-detection-of-small-pulmonary-nodules
#1
REVIEW
John K Field, Michael W Marcus, Matthijs Oudkerk
The National Lung Cancer Screening trial (NLST) demonstrated that individuals assigned to the LDCT screening arm had a 20% lower mortality than those who were assigned to the conventional chest radiography. The NLST was thoroughly analyzed by the US Preventive Task Force on CT Screening and they recommended that lung cancer screening should be implemented. A number of other countries have also recommended implementation, whilst others are awaiting the outcome of the NELSON Trial. However, recommendations for the management of CT screen detected nodules have only recently had any clarity...
February 2017: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/28304338/serum-magnesium-concentrations-in-the-canadian-population-and-associations-with-diabetes-glycemic-regulation-and-insulin-resistance
#2
Jesse Bertinato, Kuan Chiao Wang, Stephen Hayward
Total serum magnesium (Mg) concentration (SMC) is commonly used to assess Mg status. This study reports current SMCs of Canadians and their associations with demographic factors, diabetes, and measures of glycemic control and insulin resistance using results from the Canadian Health Measures Survey cycle 3 (2012-2013). Associations were examined in adults aged 20-79 years using linear mixed models. Mean SMCs and percentile distributions for 11 sex-age groups between 3 and 79 years (n = 5561) are reported. SMCs were normally distributed and differences (p < 0...
March 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28299786/changing-nurse-licensing-examinations-media-analysis-and-implications-of-the-canadian-experience
#3
L McGillis Hall, M Lalonde, J Kashin, C Yoo, J Moran
AIM: This study examines perceptions of the implementation of National Council Licensing Examination in Canada through a content analysis of articles in the media. BACKGROUND: Public opinions of nursing in the media have been acknowledged as important for the profession, specifically in relation to their portrayal of nursing. INTRODUCTION: The Canadian Council of Registered Nurse Regulators began using the US-based National Council Licensing Examination as entry examination (also known widely as NCLEX) for Canada's registered nurses, discontinuing the previous Canadian Registered Nurse Examination in 2015...
March 15, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28289631/effect-of-a-caregiver-s-education-program-on-stroke-rehabilitation
#4
Sang-Eun Hong, Chang-Hwan Kim, Ee-Jin Kim, Kyung-Lim Joa, Tae-Hyun Kim, Sang-Keun Kim, Hee-Jun Han, Eui-Chang Lee, Han-Young Jung
OBJECTIVE: To evaluate effects of caregiver's education program on their satisfaction, as well as patient functional recovery, performed in addition to daily conventional rehabilitation treatment. METHODS: Three hundred eleven subjects diagnosed with first-onset stroke and transferred to the Department of Physical Medicine and Rehabilitation of Inha University Hospital were surveyed. In 2015, caregivers attended an education program for acute and subacute stroke patients...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28273035/the-association-of-household-food-security-household-characteristics-and-school-environment-with-obesity-status-among-off-reserve-first-nations-and-m%C3%A3-tis-children-and-youth-in-canada-results-from-the-2012-aboriginal-peoples-survey
#5
Jasmin Bhawra, Martin J Cooke, Yanling Guo, Piotr Wilk
INTRODUCTION: Indigenous children are twice as likely to be classified as obese and three times as likely to experience household food insecurity when compared with non- Indigenous Canadian children. The purpose of this study was to explore the relationship between food insecurity and weight status among Métis and off-reserve First Nations children and youth across Canada. METHODS: We obtained data on children and youth aged 6 to 17 years (n = 6900) from the 2012 Aboriginal Peoples Survey...
March 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28270932/the-krescent-program-2005-2015-an-evaluation-of-the-state-of-kidney-research-training-in-canada
#6
Kevin D Burns, Adeera Levin, Elisabeth Fowler, Leah Butcher, Marc Turcotte, Mary-Jo Makarchuk, Benoît Macaluso, Vincent Larivière, Philip M Sherman
BACKGROUND: The Kidney Research Scientist Core Education and National Training (KRESCENT) Program was launched in 2005 to enhance kidney research capacity in Canada and foster knowledge translation across the 4 themes of health research. OBJECTIVE: To evaluate the impact of KRESCENT on its major objectives and on the careers of trainees after its first 10 years. METHODS: An online survey of trainees (n = 53) who had completed or were enrolled in KRESCENT was conducted in 2015...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28270931/design-and-methods-of-the-pan-canadian-applying-biomarkers-to-minimize-long-term-effects-of-childhood-adolescent-cancer-treatment-able-nephrotoxicity-study-a-prospective-observational-cohort-study
#7
Kelly R McMahon, Shahrad Rod Rassekh, Kirk R Schultz, Maury Pinsk, Tom Blydt-Hansen, Cherry Mammen, Ross T Tsuyuki, Prasad Devarajan, Geoff D E Cuvelier, Lesley G Mitchell, Sylvain Baruchel, Ana Palijan, Bruce C Carleton, Colin J D Ross, Michael Zappitelli
BACKGROUND: Childhood cancer survivors experience adverse drug events leading to lifelong health issues. The Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) team was established to validate and apply biomarkers of cancer treatment effects, with a goal of identifying children at high risk of developing cancer treatment complications associated with thrombosis, graft-versus-host disease, hearing loss, and kidney damage. Cisplatin is a chemotherapy well known to cause acute and chronic nephrotoxicity...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28253219/age-dependent-changes-in-blood-pressure-over-consecutive-office-measurements-impact-on-hypertension-diagnosis-and-implications-for-international-guidelines
#8
Panagiota Veloudi, Christopher L Blizzard, Velandai K Srikanth, Monique Breslin, Martin G Schultz, James E Sharman
OBJECTIVES: Based on anecdotal belief that blood pressure (BP) drops over consecutive measurements, guidelines recommend discarding the first BP reading (Canadian Hypertension Education Program guidelines) or take only one reading if SBP less than 140 mmHg (National Institute for Health and Care Excellence). However, the extent to which SBP fluctuations affect BP classification as well as the potential effect of age are unknown. We sought to assess the change in SBP classification over consecutive measurements following different guidelines, among younger (<50 years) and older individuals (≥50 years)...
April 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28252378/immunization-information-systems-in-canada-attributes-functionality-strengths-and-challenges-a-canadian-immunization-research-network-study
#9
Sarah E Wilson, Susan Quach, Shannon E MacDonald, Monika Naus, Shelley L Deeks, Natasha S Crowcroft, Salaheddin M Mahmud, Dat Tran, Jeffrey C Kwong, Karen Tu, Caitlin Johnson, Shalini Desai
OBJECTIVES: Canada does not have a national immunization registry. Diverse systems to record vaccine uptake exist, but these have not been systematically described. Our objective was to describe the immunization information systems (IISs) and non-IIS processes used to record childhood and adolescent vaccinations, and to outline the strengths and limitations of the systems and processes. METHODS: We collected information from key informants regarding their provincial, territorial or federal organization's surveillance systems for assessing immunization coverage...
March 1, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28252367/the-economic-consequences-of-obesity-and-overweight-among-adults-in-quebec
#10
Chantal Blouin, Denis Hamel, Nathalie Vandal, Amadou Diogo Barry, Ernest Lo, Guy Lacroix, Johanne Laguë, Marie-France Langlois, Sylvie Martel, Pierre-Carl Michaud, Louis Pérusse
OBJECTIVES: This article presents the first study of the economic consequences of obesity and overweight in the Canadian province of Quebec. The article examines three types of direct costs: hospitalizations, medical visits and drug consumption; and one type of indirect cost: productivity loss due to disability. METHODS: The National Population Health Survey, conducted in all Canadian provinces by Statistics Canada between 1994 and 2011, provides self-reported longitudinal data for body mass index and the frequency of health care utilization and disability...
March 1, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28209677/narratives-in-family-medicine-a-global-perspective-the-besrour-papers-a-series-on-the-state-of-family-medicine-in-the-world
#11
REVIEW
Christine Gibson, Robert Woollard, Videsh Kapoor, David Ponka
OBJECTIVE: To explore the development of family medicine postgraduate training in countries with varying levels of resources at different stages of development of the discipline. COMPOSITION OF THE COMMITTEE: Since 2012, the College of Family Physicians of Canada has hosted the Besrour Conferences to reflect on its role in advancing the discipline of family medicine globally. The Besrour Narrative Working Group was conceived in 2012 at the first Besrour Conference...
February 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28199778/a-national-retrospective-study-of-peld-as-a-predictor-of-change-to-second-line-therapy-in-children-with-autoimmune-hepatitis
#12
Andréanne N Zizzo, Carolina Jimenez-Rivera, Joseph Kim, Richard A Schreiber, Simon C Ling, Jason Yap, Jeff Critch, Najma Ahmed, Fernando Alvarez, Binita M Kamath
BACKGROUND & AIMS: Adult studies of autoimmune hepatitis (AIH) have shown that the model of end-stage liver disease (MELD) is associated with resistance to first-line treatment. Using a multi-centre retrospective database, we sought to determine if the pediatric end-stage liver disease (PELD) score would similarly predict treatment resistance in pediatric AIH. METHODS: One hundred and seventy-one children from 13 Canadian centres who fulfilled the International Autoimmune Hepatitis Group (IAIHG) criteria were included and assessed for change to second-line therapy within 24 months of primary treatment onset...
February 15, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28185272/social-inequalities-in-tooth-loss-a-multinational-comparison
#13
Hawazin W Elani, Sam Harper, William Murray Thomson, Iris L Espinoza, Gloria C Mejia, Xiangqun Ju, Lisa M Jamieson, Ichiro Kawachi, Jay S Kaufman
OBJECTIVES: To conduct cross-national comparison of education-based inequalities in tooth loss across Australia, Canada, Chile, New Zealand and the United States. METHODS: We used nationally representative data from Australia's National Survey of Adult Oral Health; Canadian Health Measures Survey; Chile's First National Health Survey Ministry of Health; US National Health and Nutrition Examination Survey; and the New Zealand Oral Health Survey. We examined the prevalence of edentulism, the proportion of individuals having <21 teeth and the mean number of teeth present...
February 10, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28169090/peripartum-cardiomyopathy-characteristics-and-outcomes-in-canadian-aboriginal-and-non-aboriginal-women
#14
Shuangbo Liu, Sobia A Zuberi, Amrit A Malik, Brett M Hiebert, Allan Schaffer, Shelley Zieroth, Francisco J Cordova
BACKGROUND: Peripartum cardiomyopathy (PPCM) is a heterogeneous condition characterized by heart failure and left ventricular dysfunction (left ventricular ejection fraction [LVEF] < 45%) in the absence of an alternative cause and a previous diagnosis of cardiomyopathy. The Aboriginal population (Inuit, First Nations, Metis) of Canada often has barriers to health care, which can lead to delays in diagnosis and treatment. Our objectives are to describe PPCM in a Canadian population, and to determine if Canadian Aboriginal women have worse clinical outcomes than non-Aboriginal women...
November 11, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28166804/addressing-the-gaps-in-diabetes-care-in-first-nations-communities-with-the-reorganizing-the-approach-to-diabetes-through-the-application-of-registries-radar-the-project-protocol
#15
Dean T Eurich, Sumit R Majumdar, Lisa A Wozniak, Allison Soprovich, Kari Meneen, Jeffrey A Johnson, Salim Samanani
BACKGROUND: Type-2 diabetes rates in First Nations communities are 3-5 times higher than the general Canadian population, resulting in a high burden of disease, complications and comorbidity. Limited community nursing capacity, isolated environments and a lack of electronic health records (EHR)/registries lead to a reactive, disorganized approach to diabetes care for many First Nations people. The Reorganizing the Approach to Diabetes through the Application of Registries (RADAR) project was developed in alignments with federal calls for innovative, culturally relevant, community-specific programs for people with type-2 diabetes developed and delivered in partnership with target communities...
February 6, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28162932/multicenter-evaluation-of-a-national-organ-sharing-policy-for-highly-sensitized-patients-listed-for-heart-transplantation-in-canada
#16
Brian Clarke, Anique Ducharme, Nadia Giannetti, Daniel Kim, Michael McDonald, Peter Pflugfelder, Miroslaw Rajda, Mario Sénéchal, Ellie Stadnick, Mustafa Toma, Shelley Zieroth, Debra Isaac
BACKGROUND: Transplantation of sensitized recipients has been associated with increased risk of post-transplant complications. In 2010, the Canadian Cardiac Transplant Network (CCTN) created a unique status listing for highly sensitized heart transplant candidates. Status 4S listing requires calculated panel-reactive antibody (cPRA) level >80% as the sole listing criteria and enables geographic expansion of the donor pool by providing national access. In this study, we describe patient characteristics and outcomes of those transplanted as Status 4S in Canada...
January 6, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28157587/health-and-work-in-the-family-evidence-from-spouses-cancer-diagnoses
#17
Sung-Hee Jeon, R Vincent Pohl
Using Canadian administrative data from multiple sources, we provide the first nationally representative estimates for the effect of spouses' cancer diagnoses on individuals' employment and earnings and on family income. Our identification strategy exploits unexpected health shocks and combines matching with individual fixed effects in a generalized difference-in-differences framework to control for observable and unobservable heterogeneity. While the effect of spousal health shocks on labor supply is theoretically ambiguous, we find strong evidence for a decline in employment and earnings of individuals whose spouses are diagnosed with cancer...
January 20, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/28152953/cost-effectiveness-of-brentuximab-vedotin-in-relapsed-or-refractory-systemic-anaplastic-large-cell-lymphoma
#18
Denise Zou, Esprit Ma, Peter Sajosi, Andreas Engstrom, Ross Selby, Eugene Benson, Jeremy Teasell, Akshara Richhariya, Andrew Briggs, Vijayveer Bonthapally
18 Background: Systemic anaplastic large cell lymphoma (sALCL) is a rare T-cell lymphoma. For patients who fail front-line therapy, outcomes are poor and there is no current defined standard of care. Brentuximab vedotin has demonstrated high objective response rates and is approved for patients with relapsed or refractory (R/R) sALCL. However, the cost-effectiveness of brentuximab vedotin compared with conventional chemotherapy has not been explored. METHODS: A lifetime Excel-based partitioned survival model was used to compare survival outcomes from the pivotal phase-2 single-arm brentuximab vedotin trial of 58 R/R sALCL patients with good Eastern Corporative Oncology Group (ECOG) performance status after one or more prior therapies (SG035-0004); with 40 sALCL patients from a Canadian cancer registry receiving first-line conventional salvage chemotherapy (65% with ECOG 0 or 1) between 1980 and 2012 and followed for up to 20 years...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28148504/identification-of-dietary-patterns-associated-with-obesity-in-a-nationally-representative-survey-of-canadian-adults-application-of-a-priori-hybrid-and-simplified-dietary-pattern-techniques
#19
Mahsa Jessri, Russell D Wolfinger, Wendy Y Lou, Mary R L'Abbé
Background: Analyzing the effects of dietary patterns is an important approach for examining the complex role of nutrition in the etiology of obesity and chronic diseases.Objectives: The objectives of this study were to characterize the dietary patterns of Canadians with the use of a priori, hybrid, and simplified dietary pattern techniques, and to compare the associations of these patterns with obesity risk in individuals with and without chronic diseases (unhealthy and healthy obesity).Design: Dietary recalls from 11,748 participants (≥18 y of age) in the cross-sectional, nationally representative Canadian Community Health Survey 2...
March 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28117059/conduct-disorder-and-alcohol-use-disorder-trajectories-predictors-and-outcomes-for-indigenous-youth
#20
Brenna L Greenfield, Kelley J Sittner, Miriam K Forbes, Melissa L Walls, Les B Whitbeck
OBJECTIVE: The aim of this study was to identify separate and joint trajectories of conduct disorder (CD) and alcohol use disorder (AUD) DSM-IV diagnostic symptoms among American Indian and First Nation (Indigenous) youth aged 10 to 18 years, and to characterize baseline profiles and later outcomes associated with joint trajectory group membership. METHOD: Data were collected between 2002 and 2010 on three indigenous reservations in the northern Midwest and four Canadian reserves (N = 673)...
February 2017: Journal of the American Academy of Child and Adolescent Psychiatry
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