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https://www.readbyqxmd.com/read/28209677/narratives-in-family-medicine-a-global-perspective-the-besrour-papers-a-series-on-the-state-of-family-medicine-in-the-world
#1
REVIEW
Christine Gibson, Robert Woollard, Videsh Kapoor, David Ponka
OBJECTIVE: To explore the development of family medicine postgraduate training in countries with varying levels of resources at different stages of development of the discipline. COMPOSITION OF THE COMMITTEE: Since 2012, the College of Family Physicians of Canada has hosted the Besrour Conferences to reflect on its role in advancing the discipline of family medicine globally. The Besrour Narrative Working Group was conceived in 2012 at the first Besrour Conference...
February 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28199778/a-national-retrospective-study-of-peld-as-a-predictor-of-change-to-second-line-therapy-in-children-with-autoimmune-hepatitis
#2
Andréanne N Zizzo, Carolina Jimenez-Rivera, Joseph Kim, Richard A Schreiber, Simon C Ling, Jason Yap, Jeff Critch, Najma Ahmed, Fernando Alvarez, Binita M Kamath
BACKGROUND & AIMS: Adult studies of autoimmune hepatitis (AIH) have shown that the model of end-stage liver disease (MELD) is associated with resistance to first-line treatment. Using a multi-centre retrospective database, we sought to determine if the pediatric end-stage liver disease (PELD) score would similarly predict treatment resistance in pediatric AIH. METHODS: One hundred and seventy-one children from 13 Canadian centres who fulfilled the International Autoimmune Hepatitis Group (IAIHG) criteria were included and assessed for change to second-line therapy within 24 months of primary treatment onset...
February 15, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28185272/social-inequalities-in-tooth-loss-a-multinational-comparison
#3
Hawazin W Elani, Sam Harper, William Murray Thomson, Iris L Espinoza, Gloria C Mejia, Xiangqun Ju, Lisa M Jamieson, Ichiro Kawachi, Jay S Kaufman
OBJECTIVES: To conduct cross-national comparison of education-based inequalities in tooth loss across Australia, Canada, Chile, New Zealand and the United States. METHODS: We used nationally representative data from Australia's National Survey of Adult Oral Health; Canadian Health Measures Survey; Chile's First National Health Survey Ministry of Health; US National Health and Nutrition Examination Survey; and the New Zealand Oral Health Survey. We examined the prevalence of edentulism, the proportion of individuals having <21 teeth and the mean number of teeth present...
February 10, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28169090/peripartum-cardiomyopathy-characteristics-and-outcomes-in-canadian-aboriginal-and-non-aboriginal-women
#4
Shuangbo Liu, Sobia A Zuberi, Amrit A Malik, Brett M Hiebert, Allan Schaffer, Shelley Zieroth, Francisco J Cordova
BACKGROUND: Peripartum cardiomyopathy (PPCM) is a heterogeneous condition characterized by heart failure and left ventricular dysfunction (left ventricular ejection fraction [LVEF] < 45%) in the absence of an alternative cause and a previous diagnosis of cardiomyopathy. The Aboriginal population (Inuit, First Nations, Metis) of Canada often has barriers to health care, which can lead to delays in diagnosis and treatment. Our objectives are to describe PPCM in a Canadian population, and to determine if Canadian Aboriginal women have worse clinical outcomes than non-Aboriginal women...
November 11, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28166804/addressing-the-gaps-in-diabetes-care-in-first-nations-communities-with-the-reorganizing-the-approach-to-diabetes-through-the-application-of-registries-radar-the-project-protocol
#5
Dean T Eurich, Sumit R Majumdar, Lisa A Wozniak, Allison Soprovich, Kari Meneen, Jeffrey A Johnson, Salim Samanani
BACKGROUND: Type-2 diabetes rates in First Nations communities are 3-5 times higher than the general Canadian population, resulting in a high burden of disease, complications and comorbidity. Limited community nursing capacity, isolated environments and a lack of electronic health records (EHR)/registries lead to a reactive, disorganized approach to diabetes care for many First Nations people. The Reorganizing the Approach to Diabetes through the Application of Registries (RADAR) project was developed in alignments with federal calls for innovative, culturally relevant, community-specific programs for people with type-2 diabetes developed and delivered in partnership with target communities...
February 6, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28162932/multicenter-evaluation-of-a-national-organ-sharing-policy-for-highly-sensitized-patients-listed-for-heart-transplantation-in-canada
#6
Brian Clarke, Anique Ducharme, Nadia Giannetti, Daniel Kim, Michael McDonald, Peter Pflugfelder, Miroslaw Rajda, Mario Sénéchal, Ellie Stadnick, Mustafa Toma, Shelley Zieroth, Debra Isaac
BACKGROUND: Transplantation of sensitized recipients has been associated with increased risk of post-transplant complications. In 2010, the Canadian Cardiac Transplant Network (CCTN) created a unique status listing for highly sensitized heart transplant candidates. Status 4S listing requires calculated panel-reactive antibody (cPRA) level >80% as the sole listing criteria and enables geographic expansion of the donor pool by providing national access. In this study, we describe patient characteristics and outcomes of those transplanted as Status 4S in Canada...
January 6, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28157587/health-and-work-in-the-family-evidence-from-spouses-cancer-diagnoses
#7
Sung-Hee Jeon, R Vincent Pohl
Using Canadian administrative data from multiple sources, we provide the first nationally representative estimates for the effect of spouses' cancer diagnoses on individuals' employment and earnings and on family income. Our identification strategy exploits unexpected health shocks and combines matching with individual fixed effects in a generalized difference-in-differences framework to control for observable and unobservable heterogeneity. While the effect of spousal health shocks on labor supply is theoretically ambiguous, we find strong evidence for a decline in employment and earnings of individuals whose spouses are diagnosed with cancer...
January 20, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/28152953/cost-effectiveness-of-brentuximab-vedotin-in-relapsed-or-refractory-systemic-anaplastic-large-cell-lymphoma
#8
Denise Zou, Esprit Ma, Peter Sajosi, Andreas Engstrom, Ross Selby, Eugene Benson, Jeremy Teasell, Akshara Richhariya, Andrew Briggs, Vijayveer Bonthapally
: 18 Background: Systemic anaplastic large cell lymphoma (sALCL) is a rare T-cell lymphoma. For patients who fail front-line therapy, outcomes are poor and there is no current defined standard of care. Brentuximab vedotin has demonstrated high objective response rates and is approved for patients with relapsed or refractory (R/R) sALCL. However, the cost-effectiveness of brentuximab vedotin compared with conventional chemotherapy has not been explored. METHODS: A lifetime Excel-based partitioned survival model was used to compare survival outcomes from the pivotal phase-2 single-arm brentuximab vedotin trial of 58 R/R sALCL patients with good Eastern Corporative Oncology Group (ECOG) performance status after one or more prior therapies (SG035-0004); with 40 sALCL patients from a Canadian cancer registry receiving first-line conventional salvage chemotherapy (65% with ECOG 0 or 1) between 1980 and 2012 and followed for up to 20 years...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28148504/identification-of-dietary-patterns-associated-with-obesity-in-a-nationally-representative-survey-of-canadian-adults-application-of-a-priori-hybrid-and-simplified-dietary-pattern-techniques
#9
Mahsa Jessri, Russell D Wolfinger, Wendy Y Lou, Mary R L'Abbé
BACKGROUND: Analyzing the effects of dietary patterns is an important approach for examining the complex role of nutrition in the etiology of obesity and chronic diseases. OBJECTIVES: The objectives of this study were to characterize the dietary patterns of Canadians with the use of a priori, hybrid, and simplified dietary pattern techniques, and to compare the associations of these patterns with obesity risk in individuals with and without chronic diseases (unhealthy and healthy obesity)...
February 1, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28117059/conduct-disorder-and-alcohol-use-disorder-trajectories-predictors-and-outcomes-for-indigenous-youth
#10
Brenna L Greenfield, Kelley J Sittner, Miriam K Forbes, Melissa L Walls, Les B Whitbeck
OBJECTIVE: The aim of this study was to identify separate and joint trajectories of conduct disorder (CD) and alcohol use disorder (AUD) DSM-IV diagnostic symptoms among American Indian and First Nation (Indigenous) youth aged 10 to 18 years, and to characterize baseline profiles and later outcomes associated with joint trajectory group membership. METHOD: Data were collected between 2002 and 2010 on three indigenous reservations in the northern Midwest and four Canadian reserves (N = 673)...
February 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28109587/effect-of-transitioning-to-automatic-milking-systems-on-producers-perceptions-of-farm-management-and-cow-health-in-the-canadian-dairy-industry
#11
C Tse, H W Barkema, T J DeVries, J Rushen, E A Pajor
Automatic milking systems (AMS), or milking robots, are becoming increasingly common, but there is little documentation of how AMS have affected farms as a whole and what challenges and benefits producers are experiencing during their transition to AMS. The objective of this national survey was to document the effect of transitioning to AMS on producer perceptions of change in housing, farm management, and cow health. In total, 217 AMS producers were surveyed from 8 Canadian provinces. Median time since transition for respondents was 30 mo...
January 18, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28109261/genetic-diversity-extent-of-linkage-disequilibrium-and-persistence-of-gametic-phase-in-canadian-pigs
#12
Daniela A Grossi, Mohsen Jafarikia, Luiz F Brito, Marcos E Buzanskas, Mehdi Sargolzaei, Flávio S Schenkel
BACKGROUND: Knowledge on the levels of linkage disequilibrium (LD) across the genome, persistence of gametic phase between breed pairs, genetic diversity and population structure are important parameters for the successful implementation of genomic selection. Therefore, the objectives of this study were to investigate these parameters in order to assess the feasibility of a multi-herd and multi-breed training population for genomic selection in important purebred and crossbred pig populations in Canada...
January 21, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28108593/the-differentiated-effects-of-health-on-political-participation
#13
Jérôme Couture, Sandra Breux
BACKGROUND: Several studies have shown that an individual's state of health can significantly affect their decision to vote, but analysis is often only done on a single level of government; the national level. However, prior research has shown that the determining factors for voting can differ according to the level of government being considered. Our analysis is the first attempt to take a comprehensive look at the magnitude of health and political participation in a same country on different levels...
January 19, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28107109/sex-with-neighbors-canada-and-canadians-in-the-u-s-homophile-press
#14
Marc Stein
This article examines U.S. homophile magazine contributions from and representations of Canada from 1953 to 1964. Drawing on 240 articles, letters, and other items that were published in ONE, Mattachine Review, and The Ladder, the essay first reviews Canadian-authored materials and then shows that U.S. gay and lesbian movement periodicals depicted Canada as more sexually conservative than the United States in three ways and more sexually liberal in one way. The magazines presented Canada as more sexually conservative in its failure to develop an organized gay and lesbian movement, its policies and practices of sexual censorship, and its opposition to progressive homosexual law reform...
January 20, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28106469/building-a-dna-barcode-library-of-alaska-s-non-marine-arthropods
#15
Derek S Sikes, Matthew Bowser, John M Morton, Casey Bickford, Sarah Meierotto, Kyndall Hildebrandt
Climate change may result in ecological futures with novel species assemblages, trophic mismatch, and mass extinction. Alaska has a limited taxonomic workforce to address these changes. We are building a DNA barcode library to facilitate a metabarcoding approach to monitoring non-marine arthropods. Working with the Canadian Centre for DNA Barcoding, we obtained DNA barcodes from recently collected and authoritatively identified specimens in the University of Alaska Museum (UAM) Insect Collection and the Kenai National Wildlife Refuge collection...
October 21, 2016: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28092966/avian-influenza-prevalence-among-hunter-harvested-birds-in-a-remote-canadian-first-nation-community
#16
Eric N Liberda, Richard Meldrum, Nadia A Charania, Robert Davey, Leonard Js Tsuji
INTRODUCTION: Avian influenza virus (AIV) prevalence has been associated with wild game and other bird species. The contamination of these birds may pose a greater risk to those who regularly hunt and consumed infected species. Due to resident concerns communicated by local Band Council, hunter-harvested birds from a remote First Nation community in subArctic Ontario, Canada were assessed for AIV. Hunters, and especially those who live a subsistence lifestyle, are at higher risk of AIV exposure due to their increased contact with wild birds, which represent an important part of their diet...
January 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28077911/a-decade-of-data-protection-for-innovative-drugs-in-canada-issues-limitations-and-time-for-a-reassessment
#17
Megan Kendall, Declan Hamill
Drug regulators in Canada and in other nations require innovative pharmaceutical companies to submit undisclosed clinical or other data as a condition of approving the marketing of new pharmaceutical products-the origination of which involves considerable effort and investment. Data protection regulations were enacted in Canada in 2006, which-to some extent-closed a loophole in intellectual property law that had previously left innovative companies with no effective data protection for their clinical data. Although the regulations were intended to clarify and effectively implement Canada's international treaty obligations in the spirit of innovation, a review of Canada's first decade of effective data protection shows that Health Canada and Canadian courts have interpreted the scope of data protection for innovative drugs in a narrow manner that undermines and is inconsistent with the intent of the regulations...
December 1, 2016: Biotechnology Law Report
https://www.readbyqxmd.com/read/28068362/conflict-of-interest-policies-at-french-medical-schools-starting-from-the-bottom
#18
Paul Scheffer, Christian Guy-Coichard, David Outh-Gauer, Zoéline Calet-Froissart, Mathilde Boursier, Barbara Mintzes, Jean-Sébastien Borde
BACKGROUND: Medical faculties have a role in ensuring that their students are protected from undue commercial influence during their training, and are educated about professional-industry interactions. In North America, many medical faculties have introduced more stringent conflict of interest (COI) policies during the last decade. We asked whether similar steps had been taken in France. We hypothesized that such policies may have been introduced following a 2009-2010 drug safety scandal (benfluorex, Mediator) in which COIs in medicine received prominent press attention...
2017: PloS One
https://www.readbyqxmd.com/read/28056450/current-status-and-associated-human-health-risk-of-vanadium-in-soil-in-china
#19
Jie Yang, Yanguo Teng, Jin Wu, Haiyang Chen, Guoqiang Wang, Liuting Song, Weifeng Yue, Rui Zuo, Yuanzheng Zhai
A detailed assessment of vanadium contamination characteristics in China was conducted based on the first national soil pollution survey. The map overlay analysis was used to evaluate the contamination level of vanadium and the non-carcinogenic risk assessment model was calculated to quantify the vanadium exposure risks to human health. The results showed that, due to the drastically increased mining and smelting activities, 26.49% of soils were contaminated by vanadium scattered in southwest of China. According to Canadian soil quality guidelines, about 8...
December 13, 2016: Chemosphere
https://www.readbyqxmd.com/read/28050654/misalignments-of-purpose-and-power-in-an-early-canadian-interprofessional-education-initiative
#20
Sarah Whyte, Elise Paradis, Carrie Cartmill, Ayelet Kuper, Heather Boon, Corinne Hart, Saleem Razack, Mandy Pipher, Cynthia R Whitehead
Interprofessional education (IPE) has been widely incorporated into health professional curricula and accreditation standards despite an arguably thin base of evidence regarding its clinical effects, theoretical underpinnings, and social implications. To better understand how and why IPE first took root, but failed to grow, this study examines one of the earliest documented IPE initiatives, which took place at the University of British Columbia between 1960 and 1975. We examined a subset of 110 texts (academic literature, grey literature, and unpublished records) from a larger study that uses Critical Discourse Analysis to trace the emergence of IPE in Canada...
January 3, 2017: Advances in Health Sciences Education: Theory and Practice
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