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REVIEW
Tian-Jiao Chen, Bin Dong, Yanhui Dong, Jing Li, Yinghua Ma, Dongshan Liu, Yuhui Zhang, Yi Xing, Yi Zheng, Xiaomin Luo, Fangbiao Tao, Yanqing Ding, Peijin Hu, Zhiyong Zou, Bailin Pan, Ping Tang, Dongmei Luo, Yunfei Liu, Luo Li, Geffrey Nan Li, Xiaobo Tian, Xiaona Huang, Yi Song, Jun Ma, Susan M Sawyer
China is home to the second largest population of children and adolescents in the world. Yet demographic shifts mean that the government must manage the challenge of fewer children with the needs of an ageing population, while considering the delicate tension between economic growth and environmental sustainability. We mapped the health problems and risks of contemporary school-aged children and adolescents in China against current national health policies. We involved multidisciplinary experts, including young people, with the aim of identifying actionable strategies and specific recommendations to promote child and adolescent health and wellbeing...
April 18, 2024: Lancet
#22
REVIEW
Jan Scott, Frank Iorfino, William Capon, Jacob Crouse, Barnaby Nelson, Andrew M Chanen, Dominic Dwyer, Philippe Conus, Andreas Bechdolf, Aswin Ratheesh, Andrea Raballo, Alison Yung, Michael Berk, Sarah McKenna, Samuel Hockey, Alexis Hutcheon, Elizabeth Scott, Pat McGorry, Jai Shah, Ian B Hickie
Globally, 75% of depressive, bipolar, and psychotic disorders emerge by age 25 years. However, these disorders are often preceded by non-specific symptoms or attenuated clinical syndromes. Difficulties in determining optimal treatment interventions for these emerging mental disorders, and uncertainties about accounting for co-occurring psychopathology and illness trajectories, have led many youth mental health services to adopt transdiagnostic clinical staging frameworks. In this Health Policy paper, an international working group highlights ongoing challenges in applying transdiagnostic staging frameworks in clinical research and practice, and proposes refinements to the transdiagnostic model to enhance its reliability, consistent recording, and clinical utility...
April 18, 2024: Lancet Psychiatry
#23
JOURNAL ARTICLE
Udani Samarasekera
No abstract text is available yet for this article.
April 20, 2024: Lancet
#24
JOURNAL ARTICLE
Georgina Ferry
No abstract text is available yet for this article.
April 20, 2024: Lancet
#25
EDITORIAL
The Lancet
No abstract text is available yet for this article.
April 20, 2024: Lancet
#26
JOURNAL ARTICLE
Laura Álvarez-Álvarez, María Rubín-García, Facundo Vitelli-Storelli, Silvia García, Cristina Bouzas, Miguel Ángel Martínez-González, Dolores Corella, Jordi Salas-Salvadó, Mireia Malcampo, J Alfredo Martínez, Ángel M Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramon Estruch, Francisco J Tinahones, José Lapetra, Lluís Serra-Majem, Aurora Bueno-Cavanillas, Camino García Fernández, Xavier Pintó, Miguel Delgado-Rodríguez, Pilar Matía-Martín, Josep Vidal, Clotilde Vázquez, Lidia Daimiel, Emilio Ros, Ana García-Arellano, María Ángeles Martínez, José V Sorlí, María Dolores Zomeño, Antonio García-Rios, Sandra González-Palacios, Margalida Monserrat-Mesquida, Itziar Abete, Antoni Colom Fernández, Rosa Casas, Naomi Cano Ibañez, Lucía Ugarriza, M Rosa Bernal-López, Maira Bes-Rastrollo, Indira Paz-Graniel, Eva M Asensio, Montse Fitó, Antonio P Arenas Larriva, Alejandro Oncina-Cánovas, Zenaida Vázquez, María Fernández de la Puente, Alejandra Pérez-Vega, Josep A Tur, Vicente Martín-Sánchez
OBJECTIVE: To estimate the environmental impact of a dietary intervention based on an energy-reduced Mediterranean diet (MedDiet) after one year of follow-up. METHODS: Baseline and 1-year follow-up data were used for 5800 participants aged 55-75 years with metabolic syndrome in the PREDIMED-Plus study. Food intake was estimated through a validated semiquantitative food consumption frequency questionnaire, and adherence to the MedDiet was estimated through the Diet Score...
April 18, 2024: Science of the Total Environment
#27
JOURNAL ARTICLE
Thomas Steare, Glyn Lewis, Katherine Lange, Gemma Lewis
BACKGROUND: Students define academic competence across two axes: developing skills and understanding (mastery) versus comparisons with peers (performance), and achieving goals (approach) versus avoiding failure (avoidance). We aimed to examine the longitudinal association between achievement goals and adolescent depressive symptoms. METHODS: We analysed data from the Kindergarten (recruited at age 4-5 years; born between March, 1999, and February, 2000; recruited from March, 2004 to November, 2004) and Baby (recruited at age 0-1 years; born between March, 2003, and February, 2004; recruited from March, 2004 to January, 2005) cohorts of the Longitudinal Study of Australian Children...
April 17, 2024: Lancet Child & Adolescent Health
#28
JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases...
April 15, 2024: Lancet
#29
REVIEW
Alberta Hoi, Talia Igel, Chi Chiu Mok, Laurent Arnaud
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease characterised by the presence of autoantibodies towards nuclear antigens, immune complex deposition, and chronic inflammation at classic target organs such as skin, joints, and kidneys. Despite substantial advances in the diagnosis and management of SLE, the burden of disease remains high. It is important to appreciate the typical presentations and the diagnostic process to facilitate early referral and diagnosis for patients. In most patients, constitutional, mucocutaneous, and musculoskeletal symptoms represent the earliest complaints; these symptoms can include fatigue, lupus-specific rash, mouth ulcers, alopecia, joint pain, and myalgia...
April 17, 2024: Lancet
#30
JOURNAL ARTICLE
Henrik Salje, Francis M Jiggins
No abstract text is available yet for this article.
April 17, 2024: The Lancet. Microbe
#31
REVIEW
Sergi Guixé-Muntet, Sergio Quesada-Vázquez, Jordi Gracia-Sancho
Portal hypertension represents the primary non-neoplastic complication of liver cirrhosis and has life-threatening consequences, such as oesophageal variceal bleeding, ascites, and hepatic encephalopathy. Portal hypertension occurs due to increased resistance of the cirrhotic liver vasculature to portal blood flow and is further aggravated by the hyperdynamic circulatory syndrome. Existing knowledge indicates that the profibrogenic phenotype acquired by sinusoidal cells is the initial factor leading to increased hepatic vascular tone and fibrosis, which cause increased vascular resistance and portal hypertension...
April 17, 2024: Lancet. Gastroenterology & Hepatology
#32
JOURNAL ARTICLE
Cameron Sabet, John C Lin, Anthony Zhong, Dang Nguyen
No abstract text is available yet for this article.
April 17, 2024: Lancet Global Health
#33
JOURNAL ARTICLE
Oleguer Plana-Ripoll, Danni Chen, Lisbeth Mølgaard Laustsen, Natalie C Momen
No abstract text is available yet for this article.
April 17, 2024: Lancet Psychiatry
#34
JOURNAL ARTICLE
Sean Halstead, Chester Cao, Grímur Høgnason Mohr, Bjørn H Ebdrup, Toby Pillinger, Robert A McCutcheon, Joseph Firth, Dan Siskind, Nicola Warren
BACKGROUND: People with severe mental illness, such as schizophrenia-spectrum disorder and bipolar disorder, face poorer health outcomes from multiple chronic illnesses. Physical multimorbidity, the coexistence of two or more chronic physical conditions, and psychiatric multimorbidity, the coexistence of three or more psychiatric disorders, are both emerging concepts useful in conceptualising disease burden. However, the prevalence of physical and psychiatric multimorbidity in this cohort is unknown...
April 17, 2024: Lancet Psychiatry
#35
EDITORIAL
The Lancet Respiratory Medicine
No abstract text is available yet for this article.
April 17, 2024: Lancet Respiratory Medicine
#36
JOURNAL ARTICLE
Indra A Van Assche, Kristel Van Calsteren, Jurgen Lemiere, Jana Hohmann, Jeroen Blommaert, Evangeline A Huis In 't Veld, Elyce Cardonick, Charlotte LeJeune, Nelleke P B Ottevanger, Els P O Witteveen, Martine van Grotel, Marry M van den Heuvel-Eibrink, Lieven Lagae, Maarten Lambrecht, Frédéric Amant
BACKGROUND: The main data available on the safety of radiation during pregnancy originate from animal studies and from studies of survivors of atomic or nuclear disasters. The effect of radiotherapy to treat maternal cancer on fetal development is uncertain. This report presents a unique cohort and aims to determine the long-term neurocognitive, psychosocial and physical outcomes of offspring of mothers treated with radiotherapy during pregnancy. METHODS: In this international, multicentre, mixed retrospective-prospective cohort study, we recruited participants between Aug 5, 2006, and Aug 24, 2023, aged between 1·5 and 46 years, at three referral centres in Belgium, the Netherlands, and the USA...
April 16, 2024: Lancet Child & Adolescent Health
#37
JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: Despite a global epidemiological transition towards increased burden of non-communicable diseases, communicable diseases continue to cause substantial morbidity and mortality worldwide. Understanding the burden of a wide range of infectious diseases, and its variation by geography and age, is pivotal to research priority setting and resource mobilisation globally. METHODS: We estimated disability-adjusted life-years (DALYs) associated with 85 pathogens in 2019, globally, regionally, and for 204 countries and territories...
April 16, 2024: Lancet Infectious Diseases
#38
JOURNAL ARTICLE
Karen H Keddy, Tesfaye Gobena
No abstract text is available yet for this article.
April 16, 2024: Lancet Infectious Diseases
#39
JOURNAL ARTICLE
Neil Chanchlani, Simeng Lin, Claire Bewshea, Benjamin Hamilton, Amanda Thomas, Rebecca Smith, Christopher Roberts, Maria Bishara, Rachel Nice, Charlie W Lees, Shaji Sebastian, Peter M Irving, Richard K Russell, Timothy J McDonald, James R Goodhand, Tariq Ahmad, Nicholas A Kennedy
BACKGROUND: We sought to report the effectiveness of infliximab and adalimumab over the first 3 years of treatment and to define the factors that predict anti-TNF treatment failure and the strategies that prevent or mitigate loss of response. METHODS: Personalised Anti-TNF therapy in Crohn's disease (PANTS) is a UK-wide, multicentre, prospective observational cohort study reporting the rates of effectiveness of infliximab and adalimumab in anti-TNF-naive patients with active luminal Crohn's disease aged 6 years and older...
April 16, 2024: Lancet. Gastroenterology & Hepatology
#40
JOURNAL ARTICLE
Rajiv Chowdhury, Byomkesh Talukder, Paulo Cesar Basta, Jesus Olivero-Verbel, Karen Polson-Edwards, Luiz Galvao, Carlos Espinal
No abstract text is available yet for this article.
April 16, 2024: Lancet Global Health
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