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https://www.readbyqxmd.com/read/28811982/a-matched-cohort-analysis-comparing-stand-alone-cages-and-anterior-cervical-plates-used-for-anterior-cervical-discectomy-and-fusion
#1
Samuel C Overley, Robert K Merrill, Dante M Leven, Joshua J Meaike, Abhishek Kumar, Sheeraz A Qureshi
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To compare perioperative characteristics of stand-alone cages and anterior cervical plates used for anterior cervical discectomy and fusion (ACDF). METHODS: We reviewed 40 adult patients who received a stand-alone cage for elective ACDF and matched them with 40 patients who received an anterior cervical plate. We statistically compared operative time, length of stay, proportion of ambulatory cases, overall complications necessitating a trip to the ED, readmission, or reoperation related to index procedure...
August 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28809638/-four-corner-arthrodesis-of-the-wrist-with-dorsal-circular-plate-a-retrospective-monocentric-study
#2
T Zatrapa, D Veigl, J Pech, I Landor, M Šimková
PURPOSE OF THE STUDY Our study aimed to evaluate a group of patients who in the period from 2005 to 2014 underwent a four-corner arthrodesis of the wrist in our department. We also wanted to verify the hypothesis as to whether the use of conventional dorsal plate without the application of bone grafts leads to comparable results as the use of dorsal locking plates and routine application of bone grafts. MATERIAL AND METHODS Throughout the years 2005 to 2014 the four-corner arthrodesis of the wrist was performed in our department in a total of 62 patients, in two cases bilaterally...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28795210/-arthrodesis-of-the-trapeziometacarpal-joint
#3
REVIEW
T Pillukat, M Mühldorfer-Fodor, R Fuhrmann, J Windolf, J van Schoonhoven
OBJECTIVE: Bony fusion of the trapeziometacarpal joint. INDICATIONS: High demands concerning stability and strength of the thumb in primary or secondary osteoarthritis (e.g., posttraumatic osteoarthritis following injuries to the carpometacarpal joint of the thumb); instability in the absence of osteoarthritis due to malformations, ligamentous laxicity, and joint hypermobility; malformations; improvement of hand function in neurological disorders; salvage procedure after carpometacarpal arthroplasty provided bone stock is sufficient...
August 9, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28765804/integrated-fixation-cage-loosening-under-fatigue-loading
#4
Srinidhi Nagaraja, Vivek Palepu
BACKGROUND: Screw loosening is a well-known adverse event in traditional spinal fusion instrumentation. This phenomenon may hinder segmental stability of the spine leading to bony non-union. In recent years numerous lumbar integrated fixation cages (IFC) have been introduced that offer a low profile alternative to a standard cage with an anterior plate (AP+C). The fixation approach for IFCs is different than a traditional anterior approach; therefore, it is unclear whether IFCs may loosen from the surrounding bone over time...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28765028/condylar-joint-fusion-and-stabilization-by-screws-plates-in-nontraumatic-atlanto-occipital-dislocation-aod-technical-report-of-two-cases
#5
Forhad H Chowdhury, Mohammod Raziul Haque, Sarwar Murshed Alam, Noman Khaled Chowdhury, Shamsul Islam Khan, Atul Goel
BACKGROUND: Nontraumatic spontaneous atlanto-occipital dislocation (AOD) is very rare. In this report, we discuss the technical steps of condylar joint fusion and stabilization (by screws & plates) in nontraumatic AOD. So far our knowledge it is probably the first report of such techniques. MATERIAL AND METHODS: A young girl and a young man with progressive quadriparesis due to non traumatic spontaneous atlanto-occipital dislocation were managed by microsurgical reduction, fusion and stabilization of the joint by occipital condylar and C1 lateral mass screw and plate fixation after mobilization of vertebral artery...
July 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28761530/contribution-of-the-xenograft-bone-plate-screw-system-in-lumbar-transpedicular-stabilization-an-in-vivo-study-in-dogs
#6
Sani Sarigul, Hakan Salci, Huseyin Lekesiz, Seref Dogan, Resat Ozcan, Osman Sacit Gorgul, Kaya Aksoy
OBJECTIVES: Xenograft bone plate-screws (XBPSs) can be alternative tools in lumbar transpedicular stabilization (TS). The aim of this study was to show biomechanical and histopathological contribution of the XBPSs system in lumbar TS. MATERIALS AND METHODS: Fifteen (n = 15) hybrid dog and ten (n = 10) L2-4 cadaveric specimens were included in the study. The dogs were separated according to surgical techniques: L3 laminectomy and bilateral facetectomy (LBF) in Group I (experimental group [EG I] (n = 5), L3 LBF plus TS with metal plate-screws (MPSs) in Group II (EG II) (n = 5), and L3 LBF plus TS with XBPSs in Group III (EG III) (n = 5)...
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28749440/optimization-of-detection-accuracy-of-closed-loop-optical-voltage-sensors-based-on-pockels-effect
#7
Wei Deng, Hui Li, Chunxi Zhang, Pengjie Wang
The influence of optical parameters on the performance of closed-loop optical voltage sensors (OVSs) based on Pockels effect is analyzed and a control algorithm is proposed to suppress the nonlinearity caused by the unideal parameters of optical devices for optimizing the detection precision of OVSs. First, a quantified model of the feedback phase demonstrates how the optical parameters of optical devices (including light source, polarizer, 45° fusion point, Faraday rotator and half-wave plate) result in the nonlinearity of closed-loop OVSs...
July 27, 2017: Sensors
https://www.readbyqxmd.com/read/28742760/a-randomized-trial-comparing-clinical-outcomes-between-zero-profile-and-traditional-multi-level-anterior-cervical-discectomy-and-fusion-surgery-for-cervical-myelopathy
#8
Shenghua He, Hualong Feng, Zhiming Lan, Lai Juyi, Zhitao Sun, Yeguang Wang, Jian Wang, Zhiqiang Ren, Feiqiang Huang, Fuguang Xu
STUDY DESIGN: Prospective randomized study from a single center OBJECTIVE.: The purpose of this study was to compare outcomes between a zero-profile (ZP) anterior cervical discectomy and fusion (ACDF) construct to a traditional ACDF with anterior plate (ACP) in the treatment of multilevel cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA: Multi-level cervical spondylotic myelopathy can be treated by a variety of techniques, most commonly with corpectomy, ACDF, posterior cervical fusion or a combination of the three...
July 24, 2017: Spine
https://www.readbyqxmd.com/read/28738797/tibiotalocalcaneal-ttc-arthrodesis-with-reverse-philos-plate-and-medial-cannulated-screws-with-lateral-approach
#9
Jian Fan, X Zhang, Y Luo, G W You, W K Ng, Y F Yang
BACKGROUND: Tibiotalocalcaneal arthrodesis is most common and effective surgical treatment for severe hindfoot pathology, but the fusion rate is often lower than the ordinary tibiotalar arthrodesis because of the more serious joint disease associated with obvious deformity and osteoporosis. Recent literature describe tibiotalocalcaneal arthrodesis with reverse PHILOS plate with good clinical outcome result, though some patients non-union, due to eccentric force of the plate may be hidden...
July 24, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28713173/a-standard-mammography-unit-standard-3d-ultrasound-probe-fusion-prototype-first-results
#10
Rüdiger Schulz-Wendtland, Sebastian M Jud, Peter A Fasching, Arndt Hartmann, Marcus Radicke, Claudia Rauh, Michael Uder, Marius Wunderle, Paul Gass, Hanna Langemann, Matthias W Beckmann, Julius Emons
AIM: The combination of different imaging modalities through the use of fusion devices promises significant diagnostic improvement for breast pathology. The aim of this study was to evaluate image quality and clinical feasibility of a prototype fusion device (fusion prototype) constructed from a standard tomosynthesis mammography unit and a standard 3D ultrasound probe using a new method of breast compression. MATERIALS AND METHODS: Imaging was performed on 5 mastectomy specimens from patients with confirmed DCIS or invasive carcinoma (BI-RADS (™) 6)...
June 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28709833/anterior-reduction-and-fusion-for-treatment-of-massive-tear-drop-fracture-of-axis-combining-with-inferior-endplate-serious-traversed-lesion-a-retrospective-study
#11
Tao Jiang, Hong Yin, Xian-Jun Ren, Tong-Wei Chu, Wei-Dong Wang, Chang-Qing Li
BACKGROUND: Tear drop fracture of axis represents a very small percentage of injuries of the cervical spine, but there is controversy about the treatment method for tear drop fracture of axis, especially when a large avulsed fragment is significant displacement, which combined with the inferior endplate serious traversed lesion of axis. OBJECTIVE: To evaluate the clinical outcome of anterior reduction, graft fusion of C2-3 and plate fixation in the management of massive tear drop fracture of axis combining with inferior endplate serious traversed lesion of axis...
July 11, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28709686/toxicologic-evaluations-of-recombinant-liver-targeting-interferon-ifn-csp-genotoxicity-and-tegenicratoity
#12
Wenting Zeng, Chunxu Wu, Jie Wang, Lingjie Cao, Xiaobao Jin, Jiayong Zhu, Xuemei Lu
Interferon alpha as the one of FDA recommended drugs for Hepatitis B virus (HBV) infection has many side effects. Targeting IFNα to the liver may be a strategy to increase its efficacy locally and may increase efficacy of IFNα-based therapy of HBV infection. We have prepared a novel liver-targeting fusion interferon (IFN-CSP) combining IFN α2b with plasmodium region I peptide and have revealed it may be an excellent candidate as a liver-targeting anti-HBV agent. In this study, we investigated the genotoxic and teratogenic effects of IFN-CSP...
July 11, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28697082/primary-posterior-blade-plate-tibiotalar-arthrodesis-a-salvage-procedure-for-complex-nonreconstructable-pilon-fractures
#13
Ermias Abebe, Dana J Farrell, Boris Zelle, Gary Gruen
A subset of C2/C3 pilon fractures, open pilon injuries, metaphyseal bone comminution, and those involving substantial soft tissue or vascular injury may be nonreconstructable. Such injuries are at risk of progress to nonunion and failing open reduction internal fixation (ORIF). The risk of infection, malunion, and nonunion is relatively high with such injury patterns. In such cases, tibiotalar arthrodesis is performed after ORIF fails as a salvage procedure. Overall, the literature agrees that all pilon fractures will develop posttraumatic osteoarthritis, and these patients are ultimately treated with an arthrodesis or in narrow population with total ankle arthroplasty...
August 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28685162/in-vivo-indicators-of-cytoplasmic-vacuolar-and-extracellular-ph-using-phluorin2-in-candida-albicans
#14
Hélène Tournu, Arturo Luna-Tapia, Brian M Peters, Glen E Palmer
Environmental or chemically induced stresses often trigger physiological responses that regulate intracellular pH. As such, the capacity to detect pH changes in real time and within live cells is of fundamental importance to essentially all aspects of biology. In this respect, pHluorin, a pH-sensitive variant of green fluorescent protein, has provided an invaluable tool to detect such responses. Here, we report the adaptation of pHluorin2 (PHL2), a substantially brighter variant of pHluorin, for use with the human fungal pathogen Candida albicans...
July 2017: MSphere
https://www.readbyqxmd.com/read/28680006/vertebral-fracture-at-the-caudal-end-of-a-surgical-fusion-for-thoracic-vertebral-fracture-in-a-patient-with-diffuse-idiopathic-skeletal-hyperostosis-dish
#15
Hiroshi Kobayashi, Koji Otani, Kazuyuki Watanabe, Kinshi Kato, Takuya Nikaido, Shoji Yabuki, Shin-Ichi Kikuchi, Shin-Ichi Konno
The patient was an 86-year-old woman with back pain after a fall. She had no neurological findings at the initial visit. Plain radiographs and magnetic resonance imaging (MRI) showed diffuse idiopathic skeletal hyperostosis (DISH) and a Th10 fracture. Two weeks later, she started gait exercise with immobilization by a rigid orthosis. Twenty-five days later, she presented with paralysis and numbness of her legs. Computed tomography (CT) showed anterior expansion in the vertebral body of Th10. MRI showed an intramedullary high-intensity area on T2-weighted images at the same level...
July 5, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28679701/setting-up-schizosaccharomyces-pombe-crosses-matings
#16
Karl Ekwall, Geneviève Thon
Here we provide methods for setting up standard crosses with Schizosaccharomyces pombe strains. All strain genotypes and pedigrees should be recorded in a laboratory strain book. Matings between two haploid strains of interest are induced on solid medium poor in nitrogen. Usually, sporulation agar (SPA) plates are preferred, but for difficult matings it is advisable to try several mating media in parallel because one medium might allow for more efficient mating. Protoplast fusion can be used to produce zygotes from sterile mutants that fail to mate...
July 5, 2017: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/28676461/cervical-burst-fracture-in-a-patient-with-contiguous-two-level-cervical-stand-alone-cages-a-case-report
#17
Rui Feng, Joshua Loewenstern, John Caridi
BACKGROUND: Cervical stand-alone interbody cages have seen increasingly wider use over the plate-and-screw construct in single-level anterior cervical discectomy and fusion (ACDF) in the treatment of cervical disc herniation and degenerative spondylotic conditions. Despite positive clinical outcomes, the efficacy and safety of using these devices in contiguous multi-level ACDF, however, has remained controversial. CASE DESCRIPTION: This report discusses a burst fracture seen as a complication in multi-level cervical stand-alone cage use...
July 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28669859/effect-of-the-upper-instrumented-vertebral-level-upper-vs-lower-thoracic-spine-on-gait-ability-after-corrective-surgery-for-adult-spinal-deformity
#18
Mitsuru Yagi, Nobuyuki Fujita, Osahiko Tsuji, Narihiro Nagoshi, Yoshiyuki Yato, Takashi Asazuma, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
BACKGROUND CONTEXT: The relationship between gait pattern and the level of upper instrumented vertebra (UIV) in surgically treated patients with adult spinal deformity (ASD) has not been fully documented. PURPOSE: To assess the effect of UIV level for the gait pattern in ASD STUDY DESIGN/SETTING: Prospective case series. PATIENT SAMPLE: Thirty surgically treated consecutive female ASD with lumbosacral fusion (age 67.0±8.4 years; body mass index (BMI) 22...
June 29, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28668497/a-fusion-protein-of-the-synthetic-igg-binding-domain-and-aequorin-expression-and-purification-from-e-%C3%A2-coli-cells-and-its-application
#19
Satoshi Inouye, Yuiko Sahara-Miura
Aequorin is a Ca(2+)-binding photoprotein that is a complex of apoaequorin (apoAQ) and 2-peroxycoelenterazine. In this study, the fusion protein (ZZ-apoAQ) composed of the synthetic IgG-binding domain (ZZ domain) derived from Staphylococcus aureus protein A and apoAQ was expressed into the periplasmic space of Escherichia coli cells. ZZ-apoAQ was highly purified using Ni-chelate affinity chromatography followed by IgG affinity chromatography. ZZ-AQ was prepared from purified ZZ-apoAQ by incubation with coelenterazine and was characterized, including its luminescence properties...
September 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/28658103/application-of-anterior-debridement-and-reconstruction-with-anatomical-screw-plate-fixation-for-lumbosacral-tuberculosis-a-2-year-plus-follow-up
#20
Wen-Jun Wang, Wen-Kang Chen, Yi-Guo Yan, Nu-Zhao Yao, Cheng Wang
This study aimed to determine the efficacy and safety of anterior debridement and reconstruction with anatomical screw-plate fixation in patients with lumbosacral junction tuberculosis (TB).A total of 48 patients (30 males and 18 females) diagnosed with lumbosacral junction TB were included in this study. All patients underwent surgery in our institution from January 2008 to July 2014, using anterior debridement and reconstruction with anatomical screw-plate. Outcome data were evaluated before and after surgery and included lumbosacral angle, Frankel classification, bone fusion, and visual analog scale (VAS) scores...
June 2017: Medicine (Baltimore)
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