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https://www.readbyqxmd.com/read/27916669/prevalence-and-morbidity-of-undiagnosed-celiac-disease-from-a-community-based-study
#1
Rok Seon Choung, Scott A Larson, Shahryar Khaleghi, Alberto Rubio-Tapia, Inna G Ovsyannikova, Katherine S King, Joseph J Larson, Brian D Lahr, Gregory A Poland, Michael J Camilleri, Joseph A Murray
BACKGROUND & AIMS: Little is known about the prevalence and burden of undiagnosed celiac disease in individuals younger than 50 years old. We determined the prevalence and morbidity of undiagnosed celiac disease in individuals younger than 50 years in a community. METHODS: We tested sera from 31,255 residents of Olmsted County, Minnesota (younger than 50 years old) without a prior diagnosis of celiac disease assay using an assay for immunoglobulin A (IgA) against tissue transglutaminase (tTG); in subjects with positive test results, celiac disease was confirmed using an assay for endomysial IgA...
December 1, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27902406/mlvf-as-a-method-for-rapid-and-cost-effective-typing-of-animal-associated-staphylococcus-aureus-strains-from-lineages-other-than-st398
#2
Maja Kosecka-Strojek, Weronika M Ilczyszyn, Aneta Buda, Klaudia Polakowska, Krzysztof Murzyn, Tomasz Panz, Anna Bialecka, Andrzej Kasprowicz, Antoni Jakubczak, Jaroslaw Krol, Alina Wieliczko, Benedykt Wladyka, Jacek Miedzobrodzki
In veterinary medicine, Staphylococcus aureus is associated with a range of mild to severe infections. The high density of livestock in intensive farming systems increases the risk of disease spread and hampers its control and measures of prevention, making S. aureus one of the most important animal pathogens. Multiple-locus VNTR fingerprinting (MLVF) has been successfully applied to the characterization of livestock-associated methicillin-resistant Staphylococcus aureus (MRSA) ST398 but not to the characterization of a wide range of other animal isolates...
October 25, 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27900500/new-single-nucleotide-polymorphisms-snps-in-homologous-recombination-repair-genes-detected-by-microarray-analysis-in-polish-breast-cancer-patients
#3
Hanna Romanowicz, Dominik Strapagiel, Marcin Słomka, Marta Sobalska-Kwapis, Ewa Kępka, Anna Siewierska-Górska, Marek Zadrożny, Jan Bieńkiewicz, Beata Smolarz
Breast cancer is the most common cause of malignancy and mortality in women worldwide. This study aimed at localising homologous recombination repair (HR) genes and their chromosomal loci and correlating their nucleotide variants with susceptibility to breast cancer. In this study, authors analysed the association between single nucleotide polymorphisms (SNPs) in homologous recombination repair genes and the incidence of breast cancer in the population of Polish women. Blood samples from 94 breast cancer patients were analysed as test group...
November 30, 2016: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/27893660/salivary-lactate-dehydrogenase-and-aminotransferases-in-diabetic-patients
#4
Barbara Malicka, Katarzyna Skoskiewicz-Malinowska, Urszula Kaczmarek
Diabetes mellitus (DM) is a group of metabolic diseases resulting from impaired insulin secretion and/or action. DM is characterized by hyperglycemia that can lead to the dysfunction or damage of organs, including the salivary glands.The aim of this study was to compare the levels of salivary lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in diabetic patients.The study was approved by the Bioethics Committee of Wroclaw Medical University (Poland). The study comprised 90 adults of both sexes, aged 21 to 57 years...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27888819/lost-life-years-due-to-premature-deaths-caused-by-diseases-of-the-digestive-system-in-poland-in-2013
#5
Paulina Paciej, Beata Ciabiada, Irena Maniecka-Bryła
BACKGROUND: In order to evaluate the health status of a population, besides indicators measuring the incidence of diseases and deaths, potential measures are becoming more frequently used, ie. measures that take into account life-time potential of the individuals in the population. They can particularly by applied to analyse the problem of premature mortality, which is measured by lost life years. AIM: The aim of the study was to evaluate life years lost due to diseases of digestive system in Polish population in 2013...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27888816/opinions-about-vaccination-among-mothers-who-delivered-newborns-in-two-hospitals-in-krakow-and-my%C3%A5-lenice
#6
Dorota Mrożek-Budzyn, Agnieszka Kiełtyka, Elżbieta Mróz
INTRODUCTION AND OBJECTIVE: Campaigns against vaccinations in Poland have been increasingly more frequently observed in recent years, that was the reason of bigger number of parents refusing a consent for their children immunization. The aim of study was to determine the sources of information which significantly influence mothers’ opinions about vaccinations. MATERIALS AND METHODS: A survey was conducted among 154 randomly selected mothers hospitalized after childbearing in two hospitals in Krakow and Myslenice at the end of 2014 and in 2015...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27888815/acute-diarrhoea-induced-by-rotavirus-in-children-hospitalysed-in-provincial-hospital-for-infectious-diseases-in-bydgoszcz-in-2014-year
#7
Beata Smok, Katarzyna Zieniewicz-Cieślik, Ewa Smukalska, Małgorzata Pawłowska
OBJECTIVE: The aim of the present study was to describe the epidemiology and course of rotavirus infection in children hospitalized at the T. Browicz Provincial Hospital for Infectious Diseases in Bydgoszcz, Poland in 2014 year. INTRODUCTION: Rotavirus infection is responsible for over 2 millions hospitalizations per year among children under 5 year old. Rotavirus gastroenterocolitis is one of the most common cause of severe dehydration, electrolyte disturbances and metabolic acidosis, leading to 400-600 thousand deaths per year in children younger than 5 years of age worldwide...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27884116/kidney-disease-in-the-elderly-biopsy-based-data-from-14-renal-centers-in-poland
#8
Agnieszka Perkowska-Ptasinska, Dominika Deborska-Materkowska, Artur Bartczak, Tomasz Stompor, Tomasz Liberek, Barbara Bullo-Piontecka, Anna Wasinska, Agnieszka Serwacka, Marian Klinger, Jolanta Chyl, Michal Kuriga, Robert Malecki, Krzysztof Marczewski, Bogdan Hryniewicz, Tadeusz Gregorczyk, Monika Wieliczko, Stanislaw Niemczyk, Olga Rostkowska, Leszek Paczek, Magdalena Durlik
BACKGROUND: Longer life expectancy is associated with an increasing prevalence of kidney disease. Aging itself may cause renal damage, but the spectrum of kidney disorders that affect elderly patients is diverse. Few studies, mostly form US, Asia and West Europe found differences in the prevalence of some types of kidney diseases between elderly and younger patients based on renal biopsy findings, with varied proportion between glomerulopathies and arterionephrosclerosis as a dominant injury found...
November 25, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27883412/prolonged-hospitalization-of-patients-with-hospital-acquired-pneumoniae-in-the-intensive-care-unit-%C3%A2-morbidity-mortality-and-costs-of
#9
Anna Różańska, Marta Wałaszek, Zdzisław Wolak, Małgorzata Bulanda
BACKGROUND: The objective of this study was to determine epidemiological rates of hospital-acquired pneumonia (HAP) in the Polish ICU and direct costs associated with excess length of stay incurred by the hospital. MATERIAL AND METHODS: The studied data concern patients hospitalized in the years 2010–2012 in a 9-bed ICU of a multi-profile hospital in the Małopolskie Province. Centers for Disease Control and Prevention diagnostic criteria were the basis for the development of definitions of infections...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27883347/-adalimumab-as-induction-therapy-for-crohn-s-disease-one-center-study
#10
Maciej Gonciarz, Aldona Mularczyk, Dawid Szkudłapski, Iwona Piątek, Marek Kopała
: Adalimumab is a subcutaneously administered recombinant fully human monoclonal antibody targeting tumor necrosis factor alpha. It has been approved for use in Poland to treat patients with Crohn's disease under the program of Polish National Health Found since 2010. AIM: The aim of this study was to evaluate the efficacy of adalimumab monotherapy for inducing clinical remission in patients with active Crohn's disease . The primary outcome assessment was the reduction in score to 150 or below on the Crohn's Disease Activity Index (CDAI) at 12 weeks and the secondary one was the reduction in ΔCDAI of at least 100 points...
November 25, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27883286/influenza-in-poland-in-2013-and-2013-2014-epidemic-season
#11
Katarzyna Kondratiuk, Mirosław P Czarkowski, Ewelina Hallmann-Szelińska1, Ewa Staszewska, Karolina Bednarska, Ewa Cielebąk, Lidia B Brydak
OBJECTIVE: Analysis of epidemiological situation of influenza in Poland in 2013 and 2013/14 epidemic season in reference to previous years and seasons. MATERIAL AND METHODS: Analysis was based on: 1) data collected within influenza routine surveillance system in Poland, including data published in annual bulletins “Infectious diseases and poisonings in Poland” as well as unpublished data gathered in the Department of Epidemiology of the NIPH-NIH; 2) data collected within influenza system - Sentinel, and beyond this system, concerning results of virological tests carried out in 2013/14 epidemic season in the Department of Influenza Research, National Influenza Center in the NIPHNIH and/or laboratories of provincial sanitary and epidemiological stations which are gathered in the National Influenza Center...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27882810/what-has-changed-in-the-prevalence-of-hypertension-in-dialyzed-children-during-the-last-decade
#12
Marcin Tkaczyk, Małgorzata Stańczyk, Monika Miklaszewska, Katarzyna Zachwieja, Ryszard Wierciński, Roman Stankiewicz, Agnieszka Firszt-Adamczyk, Jacek Zachwieja, Halina Borzęcka, Ilona Zagożdżon, Beata Leszczyńska, Anna Medyńska, Piotr Adamczyk, Maria Szczepańska, Wojciech Fendler
BACKGROUND: Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS: Two cohorts of children were analyzed: 59 subjects dialyzed in 2013, and 134 children from the previous study performed in 2003 that were reevaluated according to the current methodology...
November 24, 2016: Renal Failure
https://www.readbyqxmd.com/read/27882679/circulation-of-porcine-parvovirus-types-1-through-6-in-serum-samples-obtained-from-six-commercial-polish-pig-farms
#13
J Cui, K Biernacka, J Fan, P F Gerber, T Stadejek, T Opriessnig
Porcine parvoviruses are small non-enveloped DNA viruses, very resistant to inactivation, and ubiquitous in the global pig population. Porcine parvovirus type 1 (PPV1) has been known since the 1960s and is a major causative agent of reproductive failure in breeding herds. During the last decade, several new parvoviruses have been identified in pigs by molecular methods and have been consecutively designated as PPV2 through PPV6. Epidemiology data for these viruses are limited, and the impact of these newly recognized parvoviruses on pigs is largely unknown...
November 24, 2016: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/27882180/concentrations-of-fetuin-a-osteoprotegerin-and-%C3%AE-klotho-in-patients-with-alcoholic-liver-cirrhosis
#14
Andrzej Prystupa, Anna Dąbrowska, Jarosław Jerzy Sak, Jerzy Tarach, Anna Toruń-Jurkowska, Patrycja Lachowska-Kotowska, Grzegorz Dzida
The aim of the present study was to evaluate the concentrations of fetuin-A, osteoprotegerin (OPG) and α-Klotho protein in patients with alcoholic cirrhosis at different stages of the disease, and to demonstrate that fetuin-A, osteoprotegin and α-Klotho may be used as markers of the severity of cirrhosis. A total of 54 patients with alcoholic liver cirrhosis treated in various hospitals in the Lublin region of Poland were randomly enrolled. The control group consisted of 18 healthy individuals without liver disease, who did not drink alcohol...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27881942/allergic-rhinitis-bronchial-asthma-and-other-allergies-in-patients-with-alzheimer-s-disease-unnoticed-issue
#15
Andrzej Bożek, Piotr Bednarski, Jerzy Jarzab
INTRODUCTION: Allergic diseases are becoming more prevalent in elderly patients. Allergic diseases have been observed in patients with Alzheimer's disease (AD). The prevalence of atopic bronchial asthma, allergic rhinitis and atopic dermatitis was analyzed in such elderly Polish population. AIM: Analysis of the presence of allergic diseases in the patients with AD in Poland, including asthma, allergic rhinoconjunctivitis and atopic dermatitis. MATERIAL AND METHODS: The recruitment of subjects with AD was conducted at 6 sites representative of Polish rural and urban areas, and 1060 subjects with a mean age of 69...
October 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27879115/preface
#16
Avner Friedman, Mirosław Lachowicz, Urszula Ledzewicz, Monika Joanna Piotrowska, Zuzanna Szymanska
This volume was inspired by the topics presented at the international conference "Micro and Macro Systems in Life Sciences" which was held on Jun 8-12, 2015 in Będlewo, Poland. System biology is an approach which tries to understand how micro systems, at the molecular and cellular levels, affect macro systems such as organs, tissue and populations. Thus it is not surprising that a major theme of this volume evolves around cancer and its treatment. Articles on this topic include models for tumor induced angiogenesis, without and with delays, metastatic niche of the bone marrow, drug resistance and metronomic chemotherapy, and virotherapy of glioma...
February 1, 2017: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/27879042/high-antibiotic-resistance-of-helicobacter-pylori-and-its-effect-on-tailored-and-empiric-eradication-of-the-organism-in-lower-silesia-poland
#17
Stanisław Ferenc, Jan Gnus, Magdalena Kościelna, Małgorzata Kinda, Andriy Yarka, Luke Stewart, Wojciech Witkiewicz
BACKGROUND: At present, the resistance to antibiotics is considered the most important reason for Helicobacter pylori (HP) eradication failure. The aim of this study was to estimate the prevalence of antimicrobial resistance of HP strains and to evaluate tailored and empiric therapeutic regimens in patients with peptic ulcer disease associated with infection of this microorganism. MATERIALS AND METHODS: Between May 2011 and February 2013, 185 consecutive Polish patients with at least one positive Helicobacter pylori test (urease test, histopathologic examination, and/or culture) underwent eradication therapy...
November 23, 2016: Helicobacter
https://www.readbyqxmd.com/read/27870541/rabies-in-poland-in-2013-and-2014
#18
Małgorzata Sadkowska-Todys, Bożena Kucharczyk
OBJECTIVE: Evaluation of the epidemiological situation of rabies in Poland in 2013 and 2014 in comparison to the previous years. MATERIAL AND METHODS: The evaluation was based on analysis of the data from individual report sent by the Epidemiological-Sanitary Stations. The data are from questionnaires of persons who were administered vaccine against rabies following exposure in Poland and beyond its territory, data from annual bulletin “Infectious diseases and poisonings in Poland in 2012-2014”(Czarkowski MP et al...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27870540/lyme-disease-in-poland-in-2014
#19
Iwona Paradowska-Stankiewicz, Irena Chrześcijańska
INTRODUCTION: Lyme disease is the most common tick-borne disease, caused by spirochetes of the Borrelia genus transmitted by ticks of the Ixodes genus. Infection caused by Borrelia burgdorferi occur throughout Poland and therefore, according also to ECDC description, the whole country should be considered as an endemic area. OBJECTIVES: The aim of this study was to assess the epidemiological situation of Lyme disease in Poland in 2014 in comparison to the previous years...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27870539/hepatitis-c-in-poland-in-2014
#20
Magdalena Rosińska, Natalia Parda, Małgorzata Stępień
INTRODUCTION: . Currently, hepatitis C (HCV infection) is one of the public health priorities worldwide. It is associated with a considerable improvement of methods undertaken to eliminate this disease. Due to the predominance of chronic infections of long asymptomatic course, the number of cases detected in successive years does not reflect the actual dynamics of the epidemiological situation of hepatitis C. To a large extent, it depends on current testing practices. The modifications in the provisions on the notification of diagnosed cases may also have an effect on the number of HCV infections registered in successive years...
2016: Przegla̧d Epidemiologiczny
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