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https://www.readbyqxmd.com/read/28815356/dent-disease-in-poland-what-we-have-learned-so-far
#1
Marcin Zaniew, Małgorzata Mizerska-Wasiak, Iga Załuska-Leśniewska, Piotr Adamczyk, Katarzyna Kiliś-Pstrusińska, Adam Haliński, Jan Zawadzki, Beata S Lipska-Ziętkiewicz, Krzysztof Pawlaczyk, Przemysław Sikora, Michael Ludwig, Maria Szczepańska
PURPOSE: Dent disease (DD) is a rare tubulopathy characterized by proximal tubular dysfunction leading to chronic kidney disease (CKD). The aim of the study was to characterize patients with DD in Poland. METHODS: A retrospective analysis of a national cohort with genetically confirmed diagnosis. RESULTS: Of 24 males, all patients except one carried mutations in the CLCN5 gene; in one patient a mutation in the OCRL gene was disclosed. Molecular diagnosis was delayed 1 year on average (range 0-21 years)...
August 16, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28800626/targeting-lysyl-oxidase-reduces-peritoneal-fibrosis
#2
Christopher R Harlow, Xuan Wu, Marielle van Deemter, Fiona Gardiner, Craig Poland, Rebecca Green, Sana Sarvi, Pamela Brown, Karl E Kadler, Yinhui Lu, J Ian Mason, Hilary O D Critchley, Stephen G Hillier
BACKGROUND: Abdominal surgery and disease cause persistent abdominal adhesions, pelvic pain, infertility and occasionally, bowel obstruction. Current treatments are ineffective and the aetiology is unclear, although excessive collagen deposition is a consistent feature. Lysyl oxidase (Lox) is a key enzyme required for crosslinking and deposition of insoluble collagen, so we investigated whether targeting Lox might be an approach to reduce abdominal adhesions. METHODS: Female C57Bl/6 mice were treated intraperitoneally with multiwalled carbon nanotubes (NT) to induce fibrosis, together with chemical (ß-aminoproprionitrile-BAPN) or miRNA Lox inhibitors, progesterone or dexamethasone...
2017: PloS One
https://www.readbyqxmd.com/read/28796982/-causes-of-death-in-children-and-adolescents-aged-1-19-in-poland-in-the-light-of-international-statistics-since-2000
#3
Joanna Mazur, Marta Malinowska-Cieślik, Anna Oblacińska
BACKGROUND: Analyses of children and young people mortality continue to be an important component of health monitoring of this population. Such analyses provide the basis to assess the overall trends, the structure of the causes of death over longer periods, and the differences between Poland and other countries. PURPOSE: The purpose of the current study is to present the current status and the direction of changes since 2000 with regard to the level and underlying causes of mortality in children and adolescents aged 1-19 years in Poland on the background of statistics for leading European countries...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28796981/-infant-and-neonatal-deaths-in-poland-in-1995-2015
#4
Katarzyna Szamotulska, Ewa Mierzejewska
AIM: The aim of the study was the analysis of trends of infant and neonatal mortality in Poland in 1995-2015, overall and by gestational age, main groups of causes and age at death. MATERIAL AND METHODS: Data from birth and death certificates from 1995, 2000, 2005, 2010, 2014 and 2015 were used. Infant, neonatal, postneonatal, perinatal and gestational age - specific mortality rates were presented. Main groups of causes of deaths were determined according to the International Classification of Diseases ICD-10...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28796563/indirect-costs-of-diabetes-and-its-impact-on-the-public-finance-the-case-of-poland
#5
Andrzej Torój, Aneta Mela
BACKGROUND: Growing public and private expenditure on healthcare results i.a. from the spreading of chronic diseases. Diabetes belongs to the most frequent ones, beyond neoplasms and cardiological diseases, and hence generates a significant burden for the public finance in terms of the direct costs, leading e.g. to the occurrence of opportunity cost of missed public investment. However, the economy suffers also from the indirect cost of diabetes that manifests itself in the loss in Gross Domestic Product (GDP) and general government revenues...
August 10, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28791815/an-outbreak-of-leptospirosis-imported-from-germany-to-poland
#6
Beata Fiecek, Tomasz Chmielewski, Małgorzata Sadkowska-Todys, Michał Czerwiński, Grażyna Zalewska, Urszula Roguska, Stanisława Tylewska-Wierzbanowska
BACKGROUND: Leptospirosis is a zoonotic disease caused by spirochetes of the Leptospiraceae family. In both humans and animals the main route of infection is indirect contact - through water or other products contaminated with urine containing spirochetes. Infection most commonly occurs through ingestion of water or food contaminated with Leptospira spp. OBJECTIVES: The aim of the study was to characterize cases of leptospirosis imported to Poland from Germany in 2014 and to analyze methods that are helpful for making a diagnosis...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28791812/relationship-between-dietary-antioxidant-index-dai-and-antioxidants-level-in-plasma-of-krak%C3%A3-w-inhabitants
#7
Emilia Kolarzyk, Agata Pietrzycka, Joanna Zając, Joanna Morawiecka-Baranek
BACKGROUND: Some literature data indicate that antioxidant-rich food may significantly increase antioxidants in serum and decrease the oxidative stress but results are ambiguous. OBJECTIVES: The aim of this study was to estimate the total antioxidant capacity of food intake among the inhabitants of Kraków, Poland on the basis of dietary antioxidant index (DAI) and evaluation the relation between DAI and the level of antioxidants in plasma. MATERIAL AND METHODS: Examination included 70 (37 women and 33 men) non-smoking inhabitants of Krakow aged 46...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28791147/two-types-of-bone-necrosis-in-the-middle-triassic-pistosaurus-longaevus-bones-the-results-of-integrated-studies
#8
Dawid Surmik, Bruce M Rothschild, Mateusz Dulski, Katarzyna Janiszewska
Avascular necrosis, diagnosed on the basis of either a specific pathological modification of the articular surfaces of bone or its radiologic appearance in vertebral centra, has been recognized in many Mesozoic marine reptiles as well as in present-day marine mammals. Its presence in the zoological and paleontologic record is usually associated with decompression syndrome, a disease that affects secondarily aquatic vertebrates that could dive. Bone necrosis can also be caused by infectious processes, but it differs in appearance from decompression syndrome-associated aseptic necrosis...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28783032/seroprevalence-of-toxoplasma-gondii-infection-in-goats-from-the-south-west-region-of-poland-and-the-detection-of-t-gondii-dna-in-goat-milk
#9
Jacek Sroka, Pawel Kusyk, Ewa Bilska-Zajac, Jacek Karamon, Jacek Dutkiewicz, Angelina Wojcik-Fatla, Violetta Zajac, Krzysztof Stojecki, Miroslaw Rozycki, Tomasz Cencek
Toxoplasma gondii (Nicolle et Manceaux, 1908) is an obligatory intracellular protozoan parasite prevalent in animals and humans worldwide having medical and veterinary importance on account of causing abortion or congenital disease in intermediate hosts, including man. Since T. gondii has already been identified in the milk of goats, Capra aegagrus hircus (Linnaeus), the possibility of acquiring infection by ingesting unpasteurised goat milk should be taken into consideration. Thus, the aim of the present study was to determine the presence of T...
July 11, 2017: Folia Parasitologica
https://www.readbyqxmd.com/read/28780991/a-simple-method-for-identification-of-misreporting-of-energy-intake-from-infancy-to-school-age-results-from-a-longitudinal-study
#10
Delphina Gomes, Veronica Luque, Annick Xhonneux, Elvira Verduci, Piotr Socha, Berthold Koletzko, Ursula Berger, Veit Grote
BACKGROUND & AIMS: Misreporting is a major source of reporting bias in nutritional surveys. It can affect the analysis of associations between diet and disease. Although various methods have been proposed to identify misreporting, their application to infants and young children is difficult. We identify misreporting of energy intake in infants and young children and propose a simplified approach. METHODS: 1199 children were enrolled in the Childhood Obesity Programme (CHOP) based in 5 European countries (Belgium, Germany, Italy, Poland and Spain) with repeated measurements of 3-day weighed food protocol and anthropometric indices at 10 time points between ages 1-96 months...
June 1, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28775385/-guidelines-for-the-preventive-health-care-of-hairdressing-apprentices
#11
Aleksandra Golińska-Zach, Marta Wiszniewska, Jolanta Walusiak-Skorupa
Hairdressing is one of the most developing branch of the service industry in Poland. Providing representatives of this occupational group with preventive health care services it should be remembered that they are at risk of skin and respiratory diseases, which occur due to a quite frequent exposure to harmful agents in the work environment of hairdressers and hairdressing apprentices. Interestingly, a much lower number of researches concentrate on respiratory symptoms than on skin disorders in hairdressers...
July 26, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28774561/personalized-vaccinology-a-review
#12
G A Poland, I G Ovsyannikova, R B Kennedy
At the current time, the field of vaccinology remains empirical in many respects. Vaccine development, vaccine immunogenicity, and vaccine efficacy have, for the most part, historically been driven by an empiric "isolate-inactivate-inject" paradigm. In turn, a population-level public health paradigm of "the same dose for everyone for every disease" model has been the normative thinking in regard to prevention of vaccine-preventable infectious diseases. In addition, up until recently, no vaccines had been designed specifically to overcome the immunosenescence of aging, consistent with a post-WWII mentality of developing vaccines and vaccine programs for children...
July 31, 2017: Vaccine
https://www.readbyqxmd.com/read/28766493/evaluation-of-the-safety-and-immunogenicity-of-subcutaneous-hx575-epoetin-alfa-in-the-treatment-of-anemia-associated-with-chronic-kidney-disease-in-predialysis-and-dialysis-patients%C3%A2
#13
Nicole Casadevall, Vladimir Dobronravov, Kai-Uwe Eckardt, Sehsuvar Ertürk, Liliya Martynyuk, Susanne Schmitt, Gregor Schaffar, Anita Rudy, Andriy Krendyukov, Marité Ode
AIM: To assess the safety and immunogenicity of subcutaneous (SC) HX575 (epoetin-α) in dialysis- and nondialysis-dependent adult patients with chronic kidney disease (CKD). METHODS: Open-label, single-arm, multicenter study in patients (n = 416) from Germany, Italy, Poland, Romania, Russia, Turkey, and Ukraine. RESULTS: Mean (standard deviation (SD)) age was 52.3 (15.8) years, all patients were Caucasian, and similar proportions were male/female...
August 2, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28762629/evaluation-of-blowfly-larvae-diptera-calliphoridae-as-possible-reservoirs-and-mechanical-vectors-of-african-swine-fever-virus
#14
J H Forth, J Amendt, S Blome, K Depner, H Kampen
In 2014, highly virulent African swine fever virus (ASFV) was introduced into the Baltic States and Poland, with new cases being reported almost every week from wild boar and also from domestic pigs. Contrary to initial predictions that the disease would either die out due to the high virulence of the virus strain or spread rapidly in westerly direction, the infection became endemic and spread slowly. The unexpected disease epidemiology led to the hypothesis that hitherto unconsidered factors might contribute to virus persistence and dispersal...
August 1, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28759738/abcb1-3435c-t-and-2677g-t-a-polymorphisms-in-polish-and-bosnian-crohn-s-disease-patients-a-preliminary-report
#15
Krzysztof Borecki, Iwona Zawada, Anna Pawinska-Matecka, Nermin Nusret Salkic, Beata Karakiewicz, Grażyna Adler
The role of ABCB1 single nucleotide polymorphisms (SNPs) in the development of Crohn's disease (CD) remains unclear. Due to inconsistent results of several European population-based studies and limited information on populations from Poland and Bosnia and Herzegovina (B&H), we conducted a preliminary association study of two main ABCB1 SNPs and CD. ABCB1 3435C>T and 2677G>T/A SNPs were analyzed in Polish and Bosnian CD patients (n = 85 and n = 30, respectively) and controls (n = 82 and n = 30, respectively) using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for 3435C>T and allele-specific PCR for 2677G>A/T SNP...
July 26, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28744132/the-most-important-psychological-and-psychosocial-needs-of-polish-multiple-sclerosis-patients-and-their-significant-others
#16
Andrzej Potemkowski, Waldemar Brola, Anna Ratajczak, Marcin Ratajczak, Mariusz Kowalewski, Małgorzata Lewita, Katarzyna Kapica-Topczewska, Joanna Tarasiuk, Adam Stępień, Katarzyna Gocyła-Dudar, Jacek Zaborski, Halina Bartosik-Psujek
BACKGROUND: People with multiple sclerosis (MS) and their relatives often have multiple, complex needs which require support from a wide range of services. The aim of the study, the first of its kind in Poland, was to identify the most important needs of patients with MS and their significant others (SO). METHODS: A questionnaire developed from focus groups consisting of 20 needs-related statements was administered in seven MS centers to 573 MS patients and 220 SO...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28742314/the-dysentery-epidemic-in-poland-in-1920-1921
#17
Jan Wnęk
This article describes in general the issues related to the dysentery epidemic in 1920-1921. The current literature on the subject lacks publications presenting these issues fully. Based on historical sources from that period, including articles published in medical magazines, the incidence rate, the methods and results of the battle against that epidemic were depicted. The article represents an important contribution to a better insight in the struggle of Polish medical services with infectious diseases afflicting people in the first years following the end of World War I...
2017: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/28740852/body-posture-postural-stability-and-metabolic-age-in-patients-with-parkinson-s-disease
#18
Jacek Wilczyński, Agnieszka Pedrycz, Dariusz Mucha, Tadeusz Ambroży, Dawid Mucha
BACKGROUND: The study aims to analyze the relationship between body posture and composition, as well as postural stability in Parkinson's disease patients. MATERIAL AND METHODS: 32 people were evaluated. The study was conducted in the Laboratory of Posturology at Jan Kochanowski University in Kielce (Poland). Body posture was examined using the optoelectronic body posture Formetric Diers Method III 4D. Postural stability was evaluated using the Biodex Balance System platform...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28737469/social-and-economic-burden-of-recurrent-urinary-tract-infections-and-quality-of-life-a-patient-web-based-study-gesprit
#19
F Wagenlehner, B Wullt, S Ballarini, D Zingg, K G Naber
Background Uncomplicated lower urinary tract infections (UTIs) occur in approximately 50% of women, and 20-30% experience recurrent UTI. Data on UTIs and quality of life (QoL) in Europe are limited. Methods This was an anonymous, self-administered web-based survey conducted in 5 countries (Germany, Switzerland, Poland, Russia and Italy), on adult women who had experienced recurrent UTI and were affected by acute UTI currently or within 4 weeks of study entry. Questions covered disease course; management; social and economic burden; education, income, and health insurance status...
July 24, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28736450/screening-survey-of-ocular-nasal-respiratory-and-skin-symptoms-in-manicurists-in-poland
#20
Marta Kieć-Świerczyńska, Dominika Świerczyńska-Machura, Dorota Chomiczewska-Skóra, Beata Kręcisz, Jolanta Walusiak-Skorupa
OBJECTIVES: Manicurists are exposed to various chemicals in nail and skin care products and may develop ocular, nasal, respiratory or skin adverse reactions to them. To investigate the occurrence of ocular, nasal, respiratory and skin problems among manicurists and to identify their causal factors, particularly allergic etiology and occupational origin. MATERIAL AND METHODS: Manicurists employed in beauty salons in the central region of Poland were invited to fill in the questionnaire and undergo medical examination, skin prick tests with common aeroallergens, patch tests with European Baseline Series and (Meth)Acrylates Series-Nails and spirometry...
July 12, 2017: International Journal of Occupational Medicine and Environmental Health
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