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https://www.readbyqxmd.com/read/29223989/geographic-variation-of-adjuvant-breast-cancer-therapy-initiation-in-the-united-states-lessons-from-medicare-part-d
#1
John A Charlson, Emily L McGinley, Ann B Nattinger, Joan M Neuner, Liliana E Pezzin
Background: Drug utilization under Medicare Part D varies significantly by geographic region. This study examined the extent to which geographic variation in Part D plan characteristics contributes to the variation in choice of initial endocrine therapy agent among women with incident breast cancer. Methods: Two-stage multivariate regression analyses were applied to the 16,541 women identified from Medicare claims as having incident breast cancer in 2006-2007. The first stage determined the effect of state of residence on the probability of having an aromatase inhibitor (AI), as opposed to tamoxifen, as initial endocrine therapy...
December 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29217271/truck-safety-evaluation-on-wyoming-mountain-passes
#2
Dick T Apronti, Promothes Saha, Milhan Moomen, Khaled Ksaibati
The Manual on Uniform Traffic Control Devices (MUTCD) for Streets and Highways recommends hill signs be placed in advance of downgrade descent of mountain passes. Mountain passes increase the risk of a runaway, or out of control trucks and so the advance warning signs inform the driver to take special precautions such as reducing speed or using lower gears during the descent. The Wyoming Department of Transportation has installed steep grade advance warning systems on Wyoming mountain passes. However, concerns for out of control trucks on the mountain passes persist...
December 4, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29214316/association-between-hospital-financial-distress-and-immediate-breast-reconstruction-surgery-after-mastectomy-among-women-with-ductal-carcinoma-in-situ
#3
Catherine A Richards, Andrew G Rundle, Jason D Wright, Dawn L Hershman
Importance: Hospital financial distress (HFD) is a state in which a hospital is at risk of closure because of its financial condition. Hospital financial distress may reduce the services a hospital can offer, particularly unprofitable ones. Few studies have assessed the association of HFD with quality of care. Objective: To examine the association between HFD and receipt of immediate breast reconstruction surgery after mastectomy among women diagnosed with ductal carcinoma in situ (DCIS)...
December 6, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29202675/acute-hepatic-steatosis-a-helpful-diagnostic-feature-in-metallic-phosphide-poisoned-horses
#4
Jonathan H Fox, Brian F Porter, Leslie Easterwood, Justin R V Hildenbrand, Pierre Hélie, James Smylie, Donal O'Toole
Metal phosphides, particularly zinc and aluminum phosphide, occasionally poison horses and other equids following their use as rodenticides and insecticides. Grain-based aluminum phosphide baits are used to control rodents such as prairie dogs. The clinical course in intoxicated horses is short (<24-48 h), and animals may be found dead. Hepatic lesions caused by phosphine poisoning are not well described. Laboratory confirmation depends on detecting phosphine gas in gastric contents. Eight horses and a mule were exposed to zinc phosphide used to control prairie dogs on a Wyoming ranch...
December 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29185977/answering-the-call-of-the-wild-creates-a-different-kind-of-medical-director
#5
Howard Wolinsky
Will Smith, the co-director of Grand Teton National Park, demonstrates some daring-do to rescue people from mishaps in the mountains of Wyoming. But just like medical directors for health systems, insurance companies, and pharmacy benefits management firms, Smith is in the business of setting policies and protocols.
November 2017: Managed Care
https://www.readbyqxmd.com/read/29146837/draft-genome-sequence-of-the-naturally-competent-bacillus-simplex-strain-wy10
#6
Eric C Keen, Valery V Bliskovsky, Sankar L Adhya, Gautam Dantas
We sequenced a naturally competent bacterial isolate, WY10, cultured from a Wyoming soil sample. Sequence analysis revealed that WY10 is a novel strain of Bacillus simplex To our knowledge, WY10 is the first B. simplex strain to be characterized as naturally competent for DNA uptake by transformation.
November 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29122312/gestational-exposure-to-volatile-organic-compounds-vocs-in-northeastern-british-columbia-canada-a-pilot-study
#7
Élyse Caron-Beaudoin, Naomi Valter, Jonathan Chevrier, Pierre Ayotte, Katherine Frohlich, Marc-André Verner
BACKGROUND: Northeastern British Columbia (Canada) is an area of intense hydraulic fracturing for unconventional natural gas exploitation. There have been multiple reports of air and water contamination by volatile organic compounds in the vicinity of gas wells. Although these chemicals are known developmental toxicants, no biomonitoring effort has been carried out in the region. OBJECTIVE: To evaluate gestational exposure to benzene and toluene in the Peace River Valley, Northeastern British Columbia (Canada)...
January 2018: Environment International
https://www.readbyqxmd.com/read/29121066/probability-of-lek-collapse-is-lower-inside-sage-grouse-core-areas-effectiveness-of-conservation-policy-for-a-landscape-species
#8
Emma Suzuki Spence, Jeffrey L Beck, Andrew J Gregory
Greater sage-grouse (Centrocercus urophasianus) occupy sagebrush (Artemisia spp.) habitats in 11 western states and 2 Canadian provinces. In September 2015, the U.S. Fish and Wildlife Service announced the listing status for sage-grouse had changed from warranted but precluded to not warranted. The primary reason cited for this change of status was that the enactment of new regulatory mechanisms was sufficient to protect sage-grouse populations. One such plan is the 2008, Wyoming Sage Grouse Executive Order (SGEO), enacted by Governor Freudenthal...
2017: PloS One
https://www.readbyqxmd.com/read/29091969/promoting-professional-identity-motivation-and-persistence-benefits-of-an-informal-mentoring-program-for-female-undergraduate-students
#9
Paul R Hernandez, Brittany Bloodhart, Rebecca T Barnes, Amanda S Adams, Sandra M Clinton, Ilana Pollack, Elaine Godfrey, Melissa Burt, Emily V Fischer
Women are underrepresented in a number of science, technology, engineering, and mathematics (STEM) disciplines. Limited diversity in the development of the STEM workforce has negative implications for scientific innovation, creativity, and social relevance. The current study reports the first-year results of the PROmoting Geoscience Research, Education, and SuccesS (PROGRESS) program, a novel theory-driven informal mentoring program aimed at supporting first- and second-year female STEM majors. Using a prospective, longitudinal, multi-site (i...
2017: PloS One
https://www.readbyqxmd.com/read/29075635/expected-net-benefit-of-vaccinating-rangeland-sheep-against-bluetongue-virus-using-a-modified-live-versus-killed-virus-vaccine
#10
Tristram R Munsick, Dannele E Peck, John P Ritten, Randall Jones, Michelle Jones, Myrna M Miller
Recurring outbreaks of bluetongue virus in domestic sheep of the US Intermountain West have prompted questions about the economic benefits and costs of vaccinating individual flocks against bluetongue (BT) disease. We estimate the cost of a BT outbreak on a representative rangeland sheep operation in the Big Horn Basin of the state of Wyoming using enterprise budgets and stochastic simulation. The latter accounts for variability in disease severity and lamb price, as well as uncertainty about when an outbreak will occur...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29074881/rancher-reported-efficacy-of-lethal-and-non-lethal-livestock-predation-mitigation-strategies-for-a-suite-of-carnivores
#11
J D Scasta, B Stam, J L Windh
Pastoralists have dealt with livestock losses from predators for millennia, yet effective mitigation strategies that balance wildlife conservation and sustainable agriculture are still needed today. In Wyoming, USA, 274 ranchers responded to a retrospective survey, and rated the efficacy of predation mitigation strategies for foxes, dogs, coyotes, wolves, bobcats, mountain lions, bears, and birds (buzzards, eagles, hawks, ravens). Rancher reported efficacy of mitigation varied by predator species, mitigation strategy, and lethality of strategies, but not livestock type...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29052009/spatial-and-temporal-variation-in-the-range-wide-cyclic-dynamics-of-greater-sage-grouse
#12
Jeffrey R Row, Bradley C Fedy
Periodic changes in abundance, or population cycles, are common in a variety of species and is one of the most widely studied ecological phenomena. The strength of, and synchrony between population cycles can vary across time and space and understanding these patterns can provide insight into the mechanisms generating population cycles and their variability within and among species. Here, we used wavelet and spectral analysis on a range-wide dataset of abundance for the greater sage-grouse (Centrocercus urophasianus) to test for regional differences in temporal cyclicity...
December 2017: Oecologia
https://www.readbyqxmd.com/read/29049389/endemic-chronic-wasting-disease-causes-mule-deer-population-decline-in-wyoming
#13
Melia T DeVivo, David R Edmunds, Matthew J Kauffman, Brant A Schumaker, Justin Binfet, Terry J Kreeger, Bryan J Richards, Hermann M Schätzl, Todd E Cornish
Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus nelsoni), and moose (Alces alces shirasi) in North America. In southeastern Wyoming average annual CWD prevalence in mule deer exceeds 20% and appears to contribute to regional population declines. We determined the effect of CWD on mule deer demography using age-specific, female-only, CWD transition matrix models to estimate the population growth rate (λ)...
2017: PloS One
https://www.readbyqxmd.com/read/29028004/geobiological-feedbacks-and-the-evolution-of-thermoacidophiles
#14
Daniel R Colman, Saroj Poudel, Trinity L Hamilton, Jeff R Havig, Matthew J Selensky, Everett L Shock, Eric S Boyd
Oxygen-dependent microbial oxidation of sulfur compounds leads to the acidification of natural waters. How acidophiles and their acidic habitats evolved, however, is largely unknown. Using 16S rRNA gene abundance and composition data from 72 hot springs in Yellowstone National Park, Wyoming, we show that hyperacidic (pH<3.0) hydrothermal ecosystems are dominated by a limited number of archaeal lineages with an inferred ability to respire O2. Phylogenomic analyses of 584 existing archaeal genomes revealed that hyperacidophiles evolved independently multiple times within the Archaea, each coincident with the emergence of the ability to respire O2, and that these events likely occurred in the recent evolutionary past...
October 13, 2017: ISME Journal
https://www.readbyqxmd.com/read/28977717/a-collaborative-in-situ-simulation-based-pediatric-readiness-improvement-program-for-community-emergency-departments
#15
Kamal Abulebda, Riad Lutfi, Travis Whitfill, Samer Abu-Sultaneh, Kellie J Leeper, Elizabeth Weinstein, Marc A Auerbach
BACKGROUND: More than 30 million children are cared for across 5,000 US emergency departments each year (ED). Most of these EDs are not facilities designed and operated solely for children. A web-based survey provided a national and state-by-state assessment of pediatric readiness and noted a national average score was 69 on a 100-point scale. This survey noted wide variations in ED readiness with scores ranging from 61 in low-pediatric-volume EDs to 90 in the high-pediatric-volume EDs...
October 4, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28951881/state-level-implementation-of-health-and-safety-policies-to-prevent-sudden-death-and-catastrophic-injuries-within-secondary-school-athletics
#16
William M Adams, Samantha E Scarneo, Douglas J Casa
BACKGROUND: Sudden death and catastrophic injuries during sport can be attenuated with the implementation of evidence-based health and safety policies. However, the extent of the implementation of these policies within secondary school athletics is unknown. PURPOSE: To provide an assessment of the implementation of health and safety policies pertaining to the leading causes of sudden death and catastrophic injuries in sport within secondary school athletics in the United States...
September 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28817520/renew-wyoming-s-answer-to-academic-progression-in-nursing
#17
Jennifer Anderson, Kathy Wells, Charlotte Mather, Mary E Burman
AIM: The aim of the study was to describe Wyoming's approach to academic progression and its projected impact. The collaborative process used to develop the shared statewide BSN curriculum is described along with recommendations. BACKGROUND: Successful educational models that address the Institute of Medicine's recommendation that 80 percent of RNs have a baccalaureate degree by 2020 face numerous challenges, especially in rural states. METHOD: ReNEW (Revolutionizing Nursing Education in Wyoming) is a creative solution designed to decrease barriers to BSN education and increase motivation through a streamlined shared curriculum building on a strong community college system and the state's one BSN program...
September 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/28810682/effects-of-known-determinants-on-methylene-bisphenyl-isocyanate-mdi-concentration-during-spray-on-truck-bed-lining-processes
#18
Nicholas C Schaal, William J Brazile, Katie L Finnie, James P Tiger
Background: Occupational exposure to methylene bisphenyl isocyanate (MDI) presents serious worker health concerns as it may lead to short- and long-term health effects such as asthma, airway irritation, hypersensitivity pneumonitis, and irritation of skin and mucous membranes. While studies of worker isocyanate exposures during vehicle painting activities are widespread, few studies have investigated the spray-on truck bed-liner (STBL) industry. The purpose of this study was to determine the effectiveness of several ventilation system variables and process characteristics in controlling MDI concentrations in the STBL industry...
August 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28809152/whole-genome-sequences-of-odocoileus-hemionus-deer-adenovirus-isolates-from-deer-moose-and-elk-are-highly-conserved-and-support-a-new-species-in-the-genus-atadenovirus
#19
Myrna M Miller, Todd E Cornish, Terry E Creekmore, Karen Fox, Will Laegreid, Jennifer McKenna, Marce Vasquez, Leslie W Woods
We present the first complete genome sequence of Odocoileus hemionus deer adenovirus 1 (OdAdV-1). This virus can cause sporadic haemorrhagic disease in cervids, although epizootics with high mortality have occurred in California. OdAdV-1 has been placed in the genus Atadenovirus, based on partial hexon, pVIII and fibre genes. Ten field isolates recovered from naturally infected mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginiana) and moose (Alces alces) from Wyoming, black-tailed deer (Odocoileus hemionus columbianus) from California, and Rocky Mountain elk (Cervus elaphus nelsoni) from Colorado and Washington state were sequenced...
September 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28796763/national-and-state-estimates-of-the-numbers-of-adults-and-children-with-active-epilepsy-united-states-2015
#20
Matthew M Zack, Rosemarie Kobau
Epilepsy, a brain disorder leading to recurring seizures, has garnered increased public health focus because persons with epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment advances, public awareness programs, and expanded rights for persons with disabilities (1,2). For almost all states, epilepsy prevalence estimates do not exist. CDC used national data sources including the 2015 National Health Interview Survey (NHIS) for adults (aged ≥18 years), the 2011-2012 National Survey of Children's Health (NSCH), and the 2015 Current Population Survey data, describing 2014 income levels, to estimate prevalent cases of active epilepsy, overall and by state, to provide information for state public health planning...
August 11, 2017: MMWR. Morbidity and Mortality Weekly Report
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