Read by QxMD icon Read


Amir Iftikhar Malik, Muhammad Ijaz, Tahir Yaqub, Muhammad Avais, Muhammad Zubair Shabbir, Hassaan Bin Aslam, Amjad Islam Aqib, Shahid Hussain Farooqi, Tayyebah Sohail, Awais Ghaffar, Ahmad Ali, Amjad Khan
Bluetongue virus (BTV) infection is an emerging hazard in small ruminants having socio-economic impacts on animals and associated people. The current study was aimed to estimate the sero-prevalence and associated risk factors in sheep and goat from Khyber Pakhtunkhwa (KP) province of Pakistan. Three distinct zones (northern, central and southern) with four districts (Mansehra, Abbottabad, Swabi, and Kohat) with a higher population of small ruminants were selected. A total of n = 408 sera originating from sheep (n = 212) and goats (n = 196) were randomly collected for detection of BTV group specific antibodies through competitive ELISA (c-ELISA)...
March 12, 2018: Acta Tropica
Jihyun An, Jong Woo Kim, Ju Hyun Shim, Seungbong Han, Chang Sik Yu, Jaewon Choe, Danbi Lee, Kang Mo Kim, Young-Suk Lim, Young-Hwa Chung, Yung Sang Lee, Dong Jin Suh, Jin Hyoung Kim, Han Chu Lee
BACKGROUND: Prior epidemiological evidences suggest that hepatitis B virus (HBV) infection is linked to cancers other than hepatocellular carcinoma. This prospective hospital registry-based case-control study aimed to investigate the sero-epidemiological association between chronic HBV infection and various types of cancer. METHODS: 95,034 patients with first-diagnosed non-hepatocellular malignancy in a tertiary hospital between 2007 and 2014; and 118,891 non-cancer individuals as controls from a health promotion center were included...
2018: PloS One
Snežana Medić, Michalis Katsilieris, Zagorka Lozanov-Crvenković, Constantinos I Siettos, Vladimir Petrović, Vesna Milošević, Snežana Brkić, Nick Andrews, Milan Ubavić, Cleo Anastassopoulou
This study aimed at establishing baseline key epidemiological parameters for varicella zoster virus (VZV) infection in Vojvodina, Serbia, with the ultimate goal to quantify the VZV transmission potential in the population. Seroprevalence data generated during the first large cross-sectional VZV serosurvey were modelled, using a two-tiered modelling approach to calculate age-specific forces of infection (FOI), the basic reproduction number (R0) and herd immunity threshold (H). Seroprevalence and modelling data were compared with corresponding pre-vaccination epidemiological parameters from 11 countries participating in the European Sero-Epidemiology Network 2 (ESEN2) project...
2018: PloS One
Xu Ru-Jin, Xia Jian-Ping, Huang Jian-Feng, Qian Chun-Yan
OBJECTIVE: To understand the status of Toxoplasma gondii infections and the awareness of toxoplasmosis prevention and control knowledge among high-risk populations in Hangzhou City. METHODS: The serum anti- T. gondii antibodies were detected in 100 HIV/AIDS patients, 100 cancer patients, 100 pregnant women and 100 healthy controls, and the awareness of toxoplasmosis prevention and control knowledge was investigated using a questionnaire. RESULTS: The sero-prevalence of T...
December 21, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Temesgen Abera, Molalegne Bitew, Debebe Gebre, Yosef Mamo, Yosef Deneke, Sukdeb Nandi
OBJECTIVE: The status of bluetongue disease, vectors for transmission of the disease and the serotypes involved are not clearly known in Ethiopia. This sero-epidemiological study was conducted to determine the seroprevalence and associated risk factors of bluetongue in small ruminants of South Western Ethiopia. RESULT: 422 serum samples were screened for the presence of bluetongue virus (BTV) specific antibodies using competitive enzyme-linked immunosorbent assay (c-ELISA) and 30...
February 8, 2018: BMC Research Notes
Jean-Patrick Molu, Marie Chantal Ngonde Essome, Chavely Gwladys Monamele, Richard Njouom
OBJECTIVE: This study was performed in order to fill the gap of knowledge regarding sero-epidemiology of hepatitis B virus (HBV) amongst Human Immunodeficiency virus (HIV)-infected patients and to assess the risk factors associated with HBV co-infection in a rural locality of Cameroon. A retrospective and cross-sectional study was carried out from January 2008 to April 2014 within the Mfou District Hospital. Naive HIV-infected patients were enrolled in the study and tested for hepatitis B surface antigen (HBsAg)...
January 16, 2018: BMC Research Notes
Yogesh K Gurav, Pragya D Yadav, Mangesh D Gokhale, Tushar R Chiplunkar, Rajlakshmi Vishwanathan, Deepak Y Patil, Rajlaxmi Jain, Anita M Shete, Savita L Patil, G D Sarang, Gajanan N Sapkal, M D Andhare, Y R Sale, Pradeep S Awate, Devendra T Mourya
INTRODUCTION: Kyasanur forest disease (KFD) outbreak was confirmed in Dodamarg Taluka, Sindhudurga district (Maharashtra) in India during the year 2016. The rise in suspected KFD cases was reported in January 2016, peaked during March, and then declined gradually from April 2016. The outbreak was thoroughly investigated considering different socio-clinical parameters. METHODS: Total, 488 suspected KFD cases were investigated using KFD specific real-time RT-PCR and anti-KFDV IgM enzyme-linked immunosorbent assay (ELISA)...
January 16, 2018: Vector Borne and Zoonotic Diseases
J Daniel Kelly, Mohamed Bailor Barrie, Annelies W Mesman, Sahr Karku, Komba Quiwa, Michael Drasher, Gabriel Warren Slough, Kerry Dierberg, Songor Koedoyoma, Christina P Lindan, James Holland Jones, Gabriel Chamie, Lee Worden, Bryan Greenhouse, Sheri D Weiser, Travis C Porco, George W Rutherford, Eugene T Richardson
Studies have yet to include minimally symptomatic Ebola virus (EBOV) infections and unrecognized Ebola virus disease (EVD) in Ebola-related transmission chains and epidemiologic risk estimates. We conducted a cross-sectional, sero-epidemiological survey from October 2015 to January 2016 among 221 individuals living in quarantined households from November 2014 to February 2015 during the Ebola outbreak in the village of Sukudu, Sierra Leone. Of 48 EBOV infected-persons, 25% (95%CI, 14-40%) had minimally symptomatic EBOV infections and 4% (95%CI, 1-14%) were unrecognized EVD cases...
January 9, 2018: Journal of Infectious Diseases
Yuta Kanai, Takahiro Kawagishi, Minoru Okamoto, Yusuke Sakai, Yoshiharu Matsuura, Takeshi Kobayashi
Pteropine orthoreovirus (PRV) is an emerging bat-borne human pathogen causing severe respiratory illness. To date, however, the evaluation of PRV virulence has largely depended on the limited numbers of clinical cases owing to the lack of animal models. To develop an in vivo model of PRV infection, an inbred C3H mouse strain was infected intranasally with pathogenic PRV strain Miyazaki-Bali/2007. C3H mice suffered severe lung infection with significant body weight reduction and died within 7 days after intranasal infection...
November 9, 2017: Virology
Belhassen Kaabi, Elyes Zhioua
During the last twenty years, zoonotic visceral leishmaniasis (ZVL) spread from the north characterized by humid, sub-humid, and semi-arid bio-climates to the arid areas located in Central Tunisia. In order to understand the eco-epidemiological factors involved in the distribution of ZVL, both a sero-epidemiological and an entomological investigation were performed in two governorates situated in two different bio-geographical areas: Bizerte in the north and Kairouan in the center. A mathematical model for transmission of ZVL was built, describing the disease dynamic in these areas...
February 2018: Acta Tropica
Muhammad Ijaz, Syed Nazar Abbas, Shahid Hussain Farooqi, Amjad Islam Aqib, Ghulam Ali Anwar, Abdul Rehman, Muhammad Muddassir Ali, Khalid Mehmood, Amjad Khan
The bovine leptospirosis is an economically important zoonotic disease of flood affected areas worldwide, but scarce information is available about its epidemiology in Pakistan. This is a first study on sero-epidemiology of bovine leptospirosis in Pakistan. The objectives of this study were to investigate the sero-prevalence and associated risk factors of bovine leptospirosis in flood affected zone of Punjab, Pakistan. A total of 385 serum samples were randomly collected from four tehsils of district Muzaffargarh, Pakistan...
October 2, 2017: Acta Tropica
Ana Bonell, Yoel Lubell, Paul N Newton, John A Crump, Daniel H Paris
BACKGROUND: Scrub typhus is a vector-borne zoonotic disease that can be life-threatening. There are no licensed vaccines, or vector control efforts in place. Despite increasing awareness in endemic regions, the public health burden and global distribution of scrub typhus remains poorly known. METHODS: We systematically reviewed all literature from public health records, fever studies and reports available on the Ovid MEDLINE, Embase Classic + Embase and EconLit databases, to estimate the burden of scrub typhus since the year 2000...
September 2017: PLoS Neglected Tropical Diseases
Sonam Wangda, James M Richter, Pema Kuenzang, Kinley Wangchuk, Tashi Choden, Karma Tenzin, Hoda M Malaty
AIM: Bhutan is a small mountainous country between Tibet and India with relatively homogenous population. According to the World Health Organization, gastric cancer is the most frequent cause of cancer death in Bhutan. This study examined the prevalence of Helicobacter pylori among children in Bhutan with emphasis on water source and living conditions. METHODS: A cross-sectional sero-epidemiologic study was conducted among schoolchildren who attended public schools in Thimphu, Bhutan...
September 22, 2017: Helicobacter
Lalmani Regmi, Kishor Pandey, Meena Malla, Santosh Khanal, Basu Dev Pandey
BACKGROUND: Leptospirosis is a re-emerging zoonotic disease caused by pathogenic strains of bacteria belonging to genus Leptospira whose symptoms can range from mild clinical manifestations to a severe life threatening illness. This disease may be under-recognized in resource poor settings like Nepal where many clinical laboratories lack appropriate equipment, technology and personnel for proper diagnosis. METHODS: We used IgM ELISA to estimate the sero-prevalence of leptospirosis in a group of febrile patients in a western region of Nepal...
September 18, 2017: BMC Infectious Diseases
Jane Davies, Shu Qin Li, Steven Y Tong, Rob W Baird, Miles Beaman, Geoff Higgins, Benjamin C Cowie, John R Condon, Joshua S Davis
BACKGROUND: Indigenous populations globally are disproportionately affected by chronic hepatitis B virus (HBV) infection however contemporary sero-prevalence data are often absent. In the Indigenous population of the Northern Territory (NT) of Australia the unique C4 sub-genotype of HBV universally circulates. There are no studies of the sero-prevalence, nor the impact of the vaccination program (which has a serotype mismatch compared to C4), at a population-wide level. METHODS: We examined all available HBV serology results obtained from the three main laboratories serving NT residents between 1991 and 2011...
2017: PloS One
Rachel J Abbott, Annette Pachnio, Isabela Pedroza-Pacheco, Alison M Leese, Jusnara Begum, Heather M Long, Debbie Croom-Carter, Andrea Stacey, Paul A H Moss, Andrew D Hislop, Persephone Borrow, Alan B Rickinson, Andrew I Bell
Epstein-Barr virus (EBV) is typically acquired asymptomatically in childhood. In contrast, infection later in life often leads to infectious mononucleosis (IM), a febrile illness characterized by anti-EBV IgM antibody positivity, high loads of circulating latently infected B cells, and a marked lymphocytosis caused by hyperexpansion of EBV-specific CD8(+) T cells plus a milder expansion of CD56(dim) NKG2A(+) KIR(-) natural killer (NK) cells. How the two situations compare is unclear due to the paucity of studies on clinically silent infection...
November 1, 2017: Journal of Virology
Zulkarnain Md Idris, Chim W Chan, James Kongere, Tom Hall, John Logedi, Jesse Gitaka, Chris Drakeley, Akira Kaneko
As markers of exposure anti-malaria antibody responses can help characterise heterogeneity in malaria transmission. In the present study antibody responses to Plasmodium falciparum AMA-1, MSP-119 and CSP were measured with the aim to describe transmission patterns in meso-endemic settings in Lake Victoria. Two cross-sectional surveys were conducted in Lake Victoria in January and August 2012. The study area comprised of three settings: mainland (Ungoye), large island (Mfangano) and small islands (Takawiri, Kibuogi, Ngodhe)...
August 22, 2017: Scientific Reports
S C Yadav, Ritesh Kumar, Jaideep Kumar, Meetali Singh, B C Bera, Rajender Kumar, U Tatu, Kanika Tehri
Trypanosoma evansi is a haemo-protozoan parasite responsible for the disease surra, an economically important disease of wide range of domestic and wild animals. The present diagnostic methods using soluble antigens have inherent problems like lack of standardized and reproducible antigens, as well as ethical issues. This entails further efforts for search of defined antigenic molecules with satisfying sensitivity and specificity for sero-epidemiology of trypanosomosis. In present investigation, we have identified and purified 52-55kDa immuno-dominant protein cluster in molecular mass ranges by preparatory SDS-PAGE methods from T...
August 1, 2017: Research in Veterinary Science
Ryan A Simmons, Leonard Mboera, Marie Lynn Miranda, Alison Morris, Gillian Stresman, Elizabeth L Turner, Randall Kramer, Chris Drakeley, Wendy P O'Meara
BACKGROUND: Measurements of anti-malarial antibodies are increasingly used as a proxy of transmission intensity. Most serological surveys are based on the use of cross-sectional data that, when age-stratified, approximates historical patterns of transmission within a population. Comparatively few studies leverage longitudinal data to explicitly relate individual infection events with subsequent antibody responses. METHODS: The occurrence of seroconversion and seroreversion events for two Plasmodium falciparum asexual stage antigens (MSP-1 and AMA-1) was examined using three annual measurements of 691 individuals from a cohort of individuals in a malaria-endemic area of rural east-central Tanzania...
August 2, 2017: Malaria Journal
Mayumi Fujimoto, Channarena Chuon, Shintaro Nagashima, Chikako Yamamoto, Ko Ko, Sonama Svay, Sirany Hok, Olline Lim, Masayuki Ohisa, Tomoyuki Akita, Keiko Katayama, Junko Matsuo, Kazuaki Takahashi, Junko Tanaka
AIM: This study aimed to survey the prevalence and incidence of hepatitis B (HBV) and hepatitis C virus (HCV) infection among elementary school students in Siem Reap province, Cambodia and to evaluate the effects of a national infant HBV vaccination program introduced in 2001. METHODS: The 3(rd) grade students during 2011, 2012 and 2013 Academic years were enrolled in this study and they became 5(th) or 6(th) grade students in 2014-2015 Academic year at their second time examination...
July 28, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"