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Seroepidemiology

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https://www.readbyqxmd.com/read/28241186/distribution-and-quantity-of-sites-of-john-cunningham-virus-persistence-in-immunologically-healthy-patients-correlation-with-john-cunningham-virus-antibody-and-urine-john-cunningham-virus-dna
#1
Joseph R Berger, Craig S Miller, Robert J Danaher, Kathryn Doyle, Kenneth J Simon, Elizabeth Norton, Leonid Gorelik, Ellen Cahir-McFarland, Divya Singhal, Nawaz Hack, Joseph Ryan Owens, Peter T Nelson, Janna H Neltner
Importance: Although seroepidemiological studies indicate that greater than 50% of the population has been infected with John Cunningham virus (JCV), the sites of JCV persistence remain incompletely characterized. Objective: To determine sites of JCV persistence in immunologically healthy individuals. Design, Setting, and Participants: Tissue specimens from multiple sites including brain, renal, and nonrenal tissues were obtained at autopsy performed in the Department of Pathology at the University of Kentucky from 12 immunologically healthy patients between February 9, 2011, and November 27, 2012...
February 27, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28217265/rubella-seromarkers-and-determinants-of-infection-among-tanzanian-children-and-adolescents-in-prevaccination-era-are-we-in-the-right-track
#2
Mariam M Mirambo, Said Aboud, Uwe Groß, Mtebe Majigo, Martha F Mushi, Stephen E Mshana
BACKGROUND: The World health organization advocates assessment of the burden of rubella and congenital rubella syndrome (CRS) by seroepidemiological surveys and surveillance programs in all countries without vaccination programs. Due to scarcity of data in developing countries, this study was conducted to assess the seromakers for natural rubella infection in Tanzania during prevaccination era so as to ascertain the gaps for future research and prevention strategies. METHODS: A cross-sectional study was conducted between September and October 2014...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215867/seroepidemiology-and-risk-assessment-of-toxoplasma-gondii-infection-in-captive-wild-birds-and-mammals-in-two-zoos-in-the-north-of-portugal
#3
Ana Tidy, Sara Fangueiro, Jitender P Dubey, Luís Cardoso, Ana Patrícia Lopes
Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is one of the most widespread zoonoses in the world. It can affect most warm-blooded animals but only felids are its definitive hosts. We determined seroprevalence and associated risk factors in birds and mammals kept in two zoological parks in northern Portugal. Sera from 77 birds and 42 mammals were assayed for the presence of T. gondii antibodies by the modified agglutination test (MAT, cut-off titre 20); 34.5% (41/119) were seropositive. All seropositive animals were apparently healthy except one seropostive mandarin (Aix galericulata) which had chorioretinitis...
February 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28168002/hepatitis-c-virus-seroprevalence-in-the-general-female-population-of-9-countries-in-europe-asia-and-africa
#4
Gary M Clifford, Tim Waterboer, Bolormaa Dondog, You Lin Qiao, Dimitri Kordzaia, Doudja Hammouda, Namory Keita, Nahid Khodakarami, Syed Ahsan Raza, Ang Tshering Sherpa, Witold Zatonski, Michael Pawlita, Martyn Plummer, Silvia Franceschi
BACKGROUND: New oral treatments with very high cure rates have the potential to revolutionize global management of hepatitis C virus (HCV), but population-based data on HCV infection are missing in many low and middle-income countries (LMIC). METHODS: Between 2004 and 2009, dried blood spots were collected from age-stratified female population samples of 9 countries: China, Mongolia, Poland, Guinea, Nepal, Pakistan, Algeria, Georgia and Iran. HCV antibodies were detected by a multiplex serology assay using bead-based technology...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28140784/the-prevalence-serogroup-distribution-and-risk-factors-of-meningococcal-carriage-in-adolescents-and-young-adults-in-turkey
#5
Rahmi Tuna Tekin, Ener Cagri Dinleyici, Mehmet Ceyhan, Adem Karbuz, Nuran Salman, Murat Sutçu, Zafer Kurugol, Yasemin Balliel, Melda Celik, Mustafa Hacimustafaoglu, Necdet Kuyucu, Meda Kondolot, Gülnar Sensoy, Ozge Metin, Soner Sertan Kara, Meltem Dinleyici, Omer Kılıç, Cihangul Bayhan, Venhar Gurbuz, Emre Aycan, Aygun Memedova, Arzu Karli, Gulçin Bozlu, Solmaz Celebi
The serogroup epidemiology of invasive meningococcal disease (IMD), which varies considerably by geographic region and immunization schedule, changes continuously. Meningococcal carriage data are crucial for assessing IMD epidemiology and designing f potential vaccination strategies. Meningococcal seroepidemiology in Turkey differs from that in other countries: serogroups W and B are the predominant strains for IMD during childhood, whereas no serogroup C cases were identified over the last 10 years and no adolescent peak for IMD was found...
January 31, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28121669/human-papillomavirus-antibody-response-following-haart-initiation-among-msm
#6
Jean-Damien Combes, Gary M Clifford, Matthias Egger, Matthias Cavassini, Hans H Hirsch, Christoph Hauser, Alexandra Calmy, Patrick Schmid, Enos Bernasconi, Huldrych F Günthard, Silvia Franceschi, Tim Waterboer, Alexandra U Scherrer
OBJECTIVE: To describe effects of HAART on high-risk human papillomavirus (HPV) antibody response in HIV-positive MSM and the meaning of this response for subsequent HPV-related cancer risk. DESIGN: Prospective seroepidemiological study of 281 HIV-positive MSM initiating HAART between 1995 and 2004 in the Swiss HIV Cohort Study. METHODS: For each individual, two serum samples, one at HAART initiation (pre-HAART) and another 24 months later (post-HAART), were tested for L1 antibodies to HPV6, 11, 16, 18, 31, 33, 35, 45, 52 and 58, as well as HPV16-E6 antibodies, using a multiplex serology assay...
February 20, 2017: AIDS
https://www.readbyqxmd.com/read/28121005/seroepidemiology-of-hepatitis-b-and-c-virus-infections-among-blood-donors-in-ethiopia
#7
Gadissa Bedada Hundie, Victor Stalin Raj, Daniel GebreMichael, Bart L Haagmans
This study was conducted to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among blood donors in different regions in Ethiopia. A total of 56 885 sera were tested for HBsAg and anti-HCV antibodies. Of these, 3.9% were found HBsAg-positive, 0.52% anti-HCV-positive, and 0.054% dual positive. HBV prevalence was relatively higher in Adama (5.91%) than Gondar (4.05%), Jimma (3.87%), Addis Ababa (3.75%), and Tigray (3.7%); and in males (4.64%) than females (2.1%). Overall, HBV and HCV prevalence increased with age...
January 25, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28108298/trichodysplasia-spinulosa-polyomavirus-infection-occurs-during-early-childhood-with-intra-familial-transmission-especially-from-mother-to-child
#8
Vincent Pedergnana, Claire Martel-Jantin, Jérôme Tj Nicol, Valérie Leblond, Patricia Tortevoye, Pierre Coursaget, Antoine Touzé, Laurent Abel, Antoine Gessain
To get new insights into the distribution and modes of acquisition of trichodysplasia spinulosa polyomavirus (TSPyV) infection, we performed a seroepidemiological study in two populations from Cameroon. Our results suggest that TSPyV infection occurs, through close contacts, during early childhood with intra-familial transmission, especially from mother to child.
January 17, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28096863/seroepidemiological-study-of-toxocariasis-in-the-owners-of-domestic-cats-and-dogs-in-mashhad-northeastern-iran
#9
Fariba Berenji, Ali Pouryousef, Abdolmajid Fata, Mahmoud Mahmoudi, Maryam Salehi, Javad Khoshnegah
BACKGROUND: Toxocariasis is the clinical terms applied to infection of human with Ascarid nematodes in the order Ascaridida, named Toxocara canis and T. cati. Because in recent years in Iran many people desire to keep pets (cats and dogs), and lacking of seroepidemiological study of toxocariasis in Mashhad, we decided to determine the seroprevalence of toxocariasis among people who own cats and dogs in comparison with control group. METHODS: A serological study for detection antibodies to Toxocara in two groups (93 cat and dog owners and 93 healthy people as control group) was conducted from Feb 2013 to Dec 2013...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28093542/disease-burden-of-dengue-in-the-philippines-adjusting-for-underreporting-by-comparing-active-and-passive-dengue-surveillance-in-punta-princesa-cebu-city
#10
Eduardo A Undurraga, Frances E Edillo, Jonathan Neil V Erasmo, Maria Theresa P Alera, In-Kyu Yoon, Francisco M Largo, Donald S Shepard
Dengue virus (DENV) is a serious threat to public health. Having reliable estimates of the burden of dengue is important to inform policy and research, but surveillance systems are not designed to capture all symptomatic DENV infections. We derived the rate of reporting of dengue by comparing active surveillance of symptomatic DENV infections in a prospective community-based seroepidemiological cohort study (N = 1008) of acute febrile illness in Punta Princesa, Cebu City, Philippines, with passive surveillance data from the Cebu City Health Department...
January 16, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28081120/epidemiology-of-chikungunya-virus-outbreaks-in-guadeloupe-and-martinique-2014-an-observational-study-in-volunteer-blood-donors
#11
Pierre Gallian, Isabelle Leparc-Goffart, Pascale Richard, Françoise Maire, Olivier Flusin, Rachid Djoudi, Jacques Chiaroni, Remi Charrel, Pierre Tiberghien, Xavier de Lamballerie
BACKGROUND: During Dec-2013, a chikungunya virus (CHIKV) outbreak was first detected in the French-West Indies. Subsequently, the virus dispersed to other Caribbean islands, continental America and many islands in the Pacific Ocean. Previous estimates of the attack rate were based on declaration of clinically suspected cases. METHODS/PRINCIPAL FINDINGS: Individual testing for CHIKV RNA of all (n = 16,386) blood donations between Feb-24th 2014 and Jan-31st 2015 identified 0·36% and 0·42% of positives in Guadeloupe and Martinique, respectively...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28077743/seroepidemiology-of-human-brucellosis-among-blood-donors-in-southern-ethiopia-calling-attention-to-a-neglected-zoonotic-disease
#12
Bereket Workalemahu, Tsegaye Sewunet, Ayalew Astatkie
Human brucellosis is neglected in southern Ethiopia. Although traditional food processing practices and animal husbandry which increase the risk of brucellosis are common, it has not been properly studied yet. This study was conducted to determine the seroepidemiology of brucellosis among apparently healthy individuals in southern Ethiopia. In the study, blood samples were collected to screen for serum agglutinins reactive to stained antigen of Brucella abortus Standard tube titration was performed for reactive serum to determine the titer of the agglutinin...
January 11, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28071799/seroepidemiological-and-phylogenetic-characterisation-of-neurotropic-enteroviruses-in-ireland-2005-2014
#13
Jorge Abboud Guerra, Allison Waters, Alison Kelly, Ursula Morley, Paul O'Reilly, Edwin O'Kelly, Jonathan Dean, Robert Cunney, Piaras O'Lorcain, Suzanne Cotter, Jeff Connell, Joanne O'Gorman, William W Hall, Michael Carr, Cillian F De Gascun
Enteroviruses (EVs) are associated with a broad spectrum of clinical presentation, including aseptic meningitis (AM), encephalitis, hand, foot and mouth disease, acute flaccid paralysis and acute flaccid myelitis. Epidemics occur sporadically and are associated with increased cases of AM in children. The present study describes the seroepidemiological analysis of circulating EVs in Ireland from 2005-2014 and phylogenetic characterisation of echovirus 30 (E-30), enterovirus A71 (EV-A71) and enterovirus D68 (EV-D68)...
January 10, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28060834/estimating-the-cost-effectiveness-of-one-time-screening-and-treatment-for-hepatitis-c-in-korea
#14
Do Young Kim, Kwang-Hyub Han, Byungyool Jun, Tae Hyun Kim, Sohee Park, Thomas Ward, Samantha Webster, Phil McEwan
BACKGROUND AND AIMS: This study aims to investigate the cost-effectiveness of a one-time hepatitis C virus (HCV) screening and treatment program in South Korea where hepatitis B virus (HBV) prevails, in people aged 40-70, compared to current practice (no screening). METHODS: A published Markov model was used in conjunction with a screening and treatment decision tree to model patient cohorts, aged 40-49, 50-59 and 60-69 years, distributed across chronic hepatitis C (CHC) and compensated cirrhosis (CC) health states (82...
2017: PloS One
https://www.readbyqxmd.com/read/28057191/comparative-seroepidemiology-of-genital-human-papillomavirus-infections-in-the-general-population-in-singapore
#15
N K H Khoo, L Tan, W Y Lim, M I C Chen, V T K Chow
No abstract text is available yet for this article.
2017: Public Health
https://www.readbyqxmd.com/read/28049479/sequence-conservation-of-plasmodium-vivax-glutamate-dehydrogenase-among-korean-isolates-and-its-application-in-seroepidemiology
#16
Bomin Seol, Hyun-Il Shin, Jung-Yeon Kim, Bo-Young Jeon, Yoon-Joong Kang, Jhang-Ho Pak, Tong-Soo Kim, Hyeong-Woo Lee
BACKGROUND: Glutamate dehydrogenase of malaria parasites (pGDH) is widely used in rapid diagnostic tests for malaria. Variation in the pGDH gene among Korean isolates of Plasmodium vivax was analysed, and a recombinant pGDH protein was evaluated for use as antigens for the serodiagnosis of vivax malaria. METHODS: Genomic DNA was purified from blood samples of 20 patients and the pGDH gene of P. vivax was sequenced. Recombinant protein was prepared to determine the antigenicity of pGDH by enzyme-linked immunosorbent assay (ELISA)...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28033239/seroprevalence-of-hepatitis-e-virus-antibodies-in-portuguese-children
#17
Ricardo Oliveira, João Rodrigo Mesquita, Sara Pereira, Joana Abreu-Silva, Joana Teixeira, Maria São José Nascimento
BACKGROUND: Hepatitis E virus (HEV) has become a growing Public Health concern in industrialized countries. Most of the HEV seroprevalence studies have focused on adult populations and reports regarding HEV seroepidemiology among children are scarce in these countries. The aims of the present work were to perform a nationwide seroprevalence study on HEV infection in Portuguese children and to compare the HEV seropositivity in this 2015 children cohort with results in sera performed 20 years earlier...
December 28, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28027004/has-vzv-epidemiology-changed-in-italy-results-of-a-seroprevalence-study
#18
Antonella De Donno, Parvanè Kuhdari, Marcello Guido, Maria Cristina Rota, Antonino Bella, Giordana Brignole, Silvia Lupi, Adele Idolo, Armando Stefanati, Martina Del Manso, Giovanni Gabutti
The aim of the study was to evaluate if and how varicella prevalence has changed in Italy. In particular a seroprevalence study was performed, comparing it to similar surveys conducted in pre-immunization era. During 2013-2014, sera obtained from blood samples taken for diagnostic purposes or routine investigations were collected in collaboration with at least one laboratory/center for each region, following the approval of the Ethics Committee. Data were stratified by sex and age. All samples were processed in a national reference laboratory by an immunoassay with high sensitivity and specificity...
February 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27998405/-status-of-seroepidemiology-of-hepatitis-a-b-and-c-in-primary-and-middle-school-students-in-shufu-county-xinjiang-uygur-autonomous-region-of-china
#19
Z B Zhang, Z X Xue, Z G Han, Q Y Yang, X R Zheng, Tuerhong Zulipikaer, M Wang
Objective: To explore the status of seroepidemiology on hepatitis A, B and C in primary and middle school students in Shufu county, Xinjiang Uygur Autonomous Region of China (Xinjiang) and to evaluate the effect of related immunization. Methods: Students in four towns and villages were selected by cluster random sampling method. HAV-IgG, HBsAg, HBsAb and HCV-IgG were detected in Feb to May, 2015. Results: The overall HAV-IgG positive rate was 99.75%, among 4 830 primary and middle school students. The positive rates were seen 99...
December 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/27993129/hepatitis-viruses-in-ethiopia-a-systematic-review-and-meta-analysis
#20
Yeshambel Belyhun, Melanie Maier, Andargachew Mulu, Ermias Diro, Uwe Gerd Liebert
BACKGROUND: The existing seroepidemiological data on viral hepatitis in Ethiopia showed a wide variation in prevalence pattern and the clinical and public health burden have been underestimated. The aim of this systematic review and meta-analysis was to provide a clear and comprehensive estimation of viral hepatitis epidemiology and the potential clinical burdens in Ethiopia. METHODS: A comprehensive literature search was carried out from five decades (1968-2015) published studies from biomedical databases; PubMed, Google scholar, Medline and Web of Science...
December 19, 2016: BMC Infectious Diseases
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