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Seroepidemiology

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https://www.readbyqxmd.com/read/28646697/seroepidemiology-of-whooping-cough-in-the-czech-republic-estimates-of-incidence-of-infection-in-adults
#1
R Chlibek, J Smetana, R Sosovickova, K Fabianova, J Zavadilova, P Dite, P Gal, P Naplava, D Lzicarova
OBJECTIVES: Despite widespread vaccination programmes, pertussis remains a significant health burden in many countries. Low awareness of the disease, the high rate of asymptomatic cases in adults and difficulties with diagnosis could explain the under-reporting of pertussis. The lack of data on actual incidence constitutes an obstacle for public health authorities for the implementation of a vaccination strategy against pertussis in adults. The aim of this study was to evaluate the seroprevalence of antibodies against Bordetella pertussis infection in adults and to estimate the actual incidence of the disease compared with the reported incidence...
June 21, 2017: Public Health
https://www.readbyqxmd.com/read/28616474/serological-tools-for-detection-of-trichinella-infection-in-animals-and-humans
#2
REVIEW
Yong Yang, Ya Nan Cai, Ming Wei Tong, Na Sun, Yin Hua Xuan, Yan Jun Kang, Isabelle Vallée, Pascal Boireau, Shi Peng Cheng, Ming Yuan Liu
Trichinellosis is a serious foodborne zoonotic disease. It is an important threat to public health in both developing and developed countries. Human infections are strongly associated with consuming undercooked meat containing infective Trichinella larvae. The development of serological tools has enabled seroepidemiological studies and contributed to our knowledge on the importance of this parasite. Serological tests can also help the diagnosis of parasite infections in humans and the surveillance of animals...
December 2016: One Health
https://www.readbyqxmd.com/read/28613147/frequent-detection-of-merkel-cell-polyomavirus-dna-in-tissues-from-10-consecutive-autopsies
#3
Giuseppe Mancuso, Jlenia Antona, Camilla Sirini, Michela Salvo, Lorenzo Giacometti, Carlotta Olivero, Elena Trisolini, Rossella Indellicato, Renzo Boldorini
Merkel cell polyomavirus (MCPyV) has been identified in samples of Merkel cell carcinoma (MCC), an aggressive skin cancer. Seroepidemiologic studies indicated a high frequency of MCPyV infection in humans, suggesting respiratory and faecal-oral routes, or transmission by skin contact. Since MCC is more frequent in immunocompromised patients, a reactivation of MCPyV latently infecting target cells has been proposed. However, neither definite ways of transmission nor specific target organs have been identified with certainty...
June 14, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28611864/entamoeba-histolytica-infection-in-female-sex-workers-a-matched-case-control-study-in-durango-mexico
#4
Cosme Alvarado-Esquivel, Luis Francisco Sanchez-Anguiano, Jesus Hernandez-Tinoco, Sergio Estrada-Martinez, Alma Rosa Perez-Alamos, Agar Ramos-Nevarez, Sandra Margarita Cerrillo-Soto, Carlos Alberto Guido-Arreola
BACKGROUND: Infection with Entamoeba histolytica (E. histolytica) can be potentially transmitted by sexual contact. The seroepidemiology of E. histolytica in female sex workers has not been studied. The aim of the study was to determine whether E. histolytica is associated with the occupation of female sex work. In addition, the correlates of E. histolytica seroprevalence in female sex workers were also investigated. METHODS: We performed an age- and gender-matched case-control study of 187 female sex workers and 374 women without sex work...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28598034/hepatitis-e-in-southern-vietnam-seroepidemiology-in-humans-and-molecular-epidemiology-in-pigs
#5
A Berto, H A Pham, T T N Thao, N H T Vy, S L Caddy, R Hiraide, N T Tue, I Goodfellow, J J Carrique-Mas, G E Thwaites, S Baker, M F Boni
Viral pathogens account for a significant proportion of the burden of emerging infectious diseases in humans. The Wellcome Trust-Vietnamese Initiative on Zoonotic Infections (WT-VIZIONS) is aiming to understand the circulation of viral zoonotic pathogens in animals that pose a potential risk to human health. Evidence suggests that human exposure and infections with hepatitis E virus (HEV) genotypes (GT) 3 and 4 results from zoonotic transmission. Hypothesising that HEV GT3 and GT4 are circulating in the Vietnamese pig population and can be transmitted to humans, we aimed to estimate the seroprevalence of HEV exposure in a population of farmers and the general population...
June 9, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28594117/serum-anti-phenolic-glycolipid-1-iga-correlates-to-igm-isotype-in-leprosy-patients-a-possible-candidate-for-seroepidemiological-surveys
#6
Alexandre C de Macedo, Juliana A Guimarães, Raphael O Rodrigues, Thiago D V Araújo, Clodis M Tavares, Paula B Cabral, Maria Isabel de Moraes-Pinto, Aparecida T Nagao-Dias
OBJECTIVE: The aim of this study was to compare serum anti-phenolic glycolipid-1 IgA, IgG, and IgM levels in leprosy patients and controls. METHOD: Analysis of anti-PGL-1 IgA, IgG, or IgM in serum samples from multibacillary (MB, n=32) and paucibacillary (PB, n=22) leprosy patients, and in non-endemic controls (n=17), using an indirect enzyme-linked immunosorbent assay. RESULTS: A strong correlation between serum IgM and IgA isotypes was found (r=...
June 8, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28592090/-a-cross-sectional-study-of-seroepidemiology-of-viral-hepatitis-among-uighurs-in-shufu-of-xinjiang
#7
Z B Zhang, Z X Xue, Q Y Yang, T M Wang, Y H Li, C Y Ma, X L Song, G Wang, D M Luo, Mahat Sulayman, Abdurahman Rayhangul, C H Zhao, Y Z Wang, M Wang
Objective: To explore the status of seroepidemiology on hepatitis A, B and C among students and residents aged equal or greater than 18 years in south Xinjiang, and to provide scientific evidence for prevention and control of viral hepatitis. Methods: Uyghur students in four towns and villages were selected by cluster random sampling from Feb to May, 2015, and Uyghur residents aged 18 to 69 years were selected by stratified cluster sampling from May to September, 2016. 4 507 middle and primary Uygur students and 4 833 Uyghur resides equal or greater than 18 years attended this survey...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28592086/-comparative-analyze-on-hepatitis-b-seroepidemiological-surveys-among-population-aged-1-29-years-in-different-epidemic-regions-of-china-in-1992-and-2014
#8
F Z Wang, G M Zhang, L P Shen, H Zheng, F Wang, N Miao, Q L Yuan, X J Sun, S L Bi, X F Liang, H Q Wang
Objective: To evaluate the effect of hepatitis B prevention and control by comparative analysis on the results of HBsAg, anti-HBs and anti-HBc prevalence from national hepatitis B seroepidemiological surveys in 1992 and 2014 in different epidemic regions of China. Methods: Data was from the national seroepidemiological surveys of hepatitis B conducted in 1992 and 2014. The survey in 1992 was conducted in 145 disease surveillance points of 30 provinces (excluding Hong Kong, Macao Special Administrative Region and Taiwan province) in China...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28592085/-the-review-and-significance-of-national-seroepidemiological-surveys-on-viral-hepatitis-in-china
#9
A Q Xu, L Zhang
No abstract text is available yet for this article.
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28591555/seroepidemiological-study-and-associated-risk-factors-of-toxocara-canis-infection-among-preschool-children-in-osun-state-nigeria
#10
Oluyomi A Sowemimo, Yueh-Lun Lee, Samuel O Asaolu, Ting-Wu Chuang, Olaoluwa P Akinwale, Bolaji O Badejoko, Vincent P Gyang, Timothy Nwafor, Emmanuel Henry, Chia-Kwung Fan
Human toxocariasis is caused by the nematode, Toxocara canis and it is a poorly understood phenomenon in Nigeria. Seroepidemiological studies have not been previously carried out among the preschool aged children in Nigeria. A cross-sectional study was conducted in pre-school children in four communities from Osun State, Nigeria between January and July 2016. A total of 308 children Aged 9 months and 5 years were studied comprising 53.2% (164/308) male and 46.8% (144/308) female. Blood samples were collected and screened for the presence of anti-Toxocara IgG antibodies by Western blot analysis based on the excretory-secretory antigens of larva T...
June 4, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28585916/mers-cov-antibody-responses-1-year-after-symptom-onset-south-korea-2015
#11
Pyoeng Gyun Choe, R A P M Perera, Wan Beom Park, Kyoung-Ho Song, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Long Wei Ronald Ko, Sang Won Park, Nam-Joong Kim, Eric H Y Lau, Leo L M Poon, Malik Peiris, Myoung-Don Oh
We investigated the kinetics of the Middle East respiratory syndrome coronavirus (MERS-CoV) neutralizing and spike protein antibody titers over the course of 1 year in 11 patients who were confirmed by reverse transcription PCR to have been infected during the outbreak in South Korea in 2015. Robust antibody responses were detected in all survivors who had severe disease; responses remained detectable, albeit with some waning, for <1 year. The duration of viral RNA detection (but not viral load) in sputum significantly correlated with the antibody response magnitude...
July 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28584712/prevalence-and-seroepidemiology-of-haemophilus-parasuis-in-sichuan-province-china
#12
Zhenghao Wang, Qin Zhao, Hailin Wei, Xintian Wen, Sanjie Cao, Xiaobo Huang, Rui Wu, Qigui Yan, Yong Huang, Yiping Wen
Haemophilus parasuis, the causative agent of Glässer's disease, has been reported as widespread, but little is known about its epidemiology in the Sichuan province of China. The goal of our research is to reveal the prevalence and distribution of H. parasuis in this area. Sampling and isolation were performed across Sichuan; isolates were processed using serotyping multiplex PCR (serotyping-mPCR) and agar gel diffusion (AGD) for confirmation of serovar identity. This study was carried out from January 2014 to May 2016 and 254 H...
2017: PeerJ
https://www.readbyqxmd.com/read/28574743/invasive-pneumococcal-infection-due-to-serotype-15a-after-the-pneumococcal-conjugate-vaccine-implementation-in-turkey
#13
Ayşe Büyükcam, Hüseyin Güdücüoğlu, Kamuran Karaman, Venhar Gürbüz, Emil Aliyev, Ateş Kara, Mehmet Ceyhan
Invasive pneumococcal infections among children are a serious public health problem in many countries, including Turkey. Pneumococcal conjugate vaccine has been included in Turkey's National Immunization Programme since 2009. We report the first two pediatric cases of invasive pneumococcal infection due to non-vaccine serotype 15A after pneumococcal conjugate vaccine implementation in Turkey. It is essential to monitor the countries' own local seroepidemiologic data for detecting selective pressure of non-vaccine serotypes of S...
June 2, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28573631/quantification-of-filovirus-glycoprotein-specific-antibodies
#14
Wakako Furuyama, Hiroko Miyamoto, Reiko Yoshida, Ayato Takada
Serological methods such as the enzyme-linked immunosorbent assay (ELISA) and virus neutralization test are fundamental tools used in diagnosis, seroepidemiological studies of filovirus transmission/prevalence, and the evaluation of vaccine immunogenicity and potential therapeutic antibodies. Filoviruses have a single transmembrane glycoprotein (GP), which is the only known target of neutralizing antibodies. Here we describe serological methods to quantify filovirus GP-specific antibodies.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28561377/country-wide-seroprevalence-studies-on-crimean-congo-hemorrhagic-fever-and-hantavirus-infections-in-general-population-of-bulgaria
#15
Iva Christova, Elitsa Panayotova, Iva Trifonova, Evgenia Taseva, Teodora Hristova, Vladislava Ivanova
Crimean-Congo hemorrhagic fever (CCHF) and hantavirus infections are the two viral hemorrhagic fevers spread in Europe. To test actual circulation of CCHF virus (CCHFV) and hantaviruses in Bulgaria, we conducted country-wide seroepidemiological studies. Serum samples were collected prospectively from 1500 residents of all 28 districts in Bulgaria. CCHFV seroprevalence of 3.7% was revealed. Anamnesis for tick bites, contact with livestock, age over 40 years and residency in Haskovo district were found as risk factors...
May 31, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28549857/low-seroprevalence-of-zika-virus-in-cameroonian-blood-donors
#16
Bouba Gake, Marie A Vernet, Isabelle Leparc-Goffart, Jan Felix Drexler, Ernest A Gould, Pierre Gallian, Xavier de Lamballerie
A Zika virus seroepidemiology study was performed in 1084 blood donors collected from August to October 2015 in six sites of Cameroon representing a large panel of eco-environments. Samples were tested using an anti-NS1 IgG ELISA detection kit and positives were further confirmed by seroneutralization. The observed global seroprevalence was low (around 5%, peaking at 10% and 7.7% in Douala and Bertoua, respectively) with risk factors associated with seropositivity pointing to the existence of a local (peri-)sylvatic cycle of transmission...
May 23, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28525973/varicella-zoster-virus-seroprevalence-in-children-and-adolescents-in-the-pre-varicella-vaccine-era-germany
#17
Miriam Wiese-Posselt, Anette Siedler, Annette Mankertz, Andreas Sauerbrei, Hartmut Hengel, Ole Wichmann, Christina Poethko-Müller
BACKGROUND: In 2004, universal childhood varicella vaccination was introduced in Germany. We aimed to determine the age-specific prevalence of anti-varicella zoster virus (VZV) IgG-antibodies among children in the pre-varicella vaccine era in Germany, to identify factors associated with VZV seropositivity, and to assess the suitability of a commercially available ELISA for VZV seroepidemiological studies by comparing it with an in-house fluorescent antibody to membrane antigen test (FAMA) as the gold standard...
May 19, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28524366/contrasting-hcv-and-hiv-seroepidemiology-in-11-years-of-blood-donors-screening-in-brazil
#18
J E Levi, S M Lira, C B Bub, M B Polite, C C Terzian, J M Kutner
BACKGROUND: Blood donors are, in principle, healthy individuals who may be revealed as infectious for blood-borne agents by the laboratory screening process, depicting the asymptomatic burden of the disease. Therefore, monitoring hepatitis C virus (HCV)-infected donor and human immunodeficiency virus (HIV)-infected donor and associating to their demographical and behavioural characteristics may shed light on the dynamics and contemporary changes in these viruses' epidemiology. METHODS: Donors presenting repeatedly reactive HCV or HIV serology/nucleic acid testing (NAT) screening results were submitted to confirmatory testing...
May 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28507471/seroepidemiological-study-of-toxoplasma-gondii-infection-in-a-population-of-iranian-epileptic-patients
#19
Jalal Babaie, Mohammad Sayyah, Kourosh Gharagozli, Ehsan Mostafavi, Majid Golkar
Epilepsy is one of the most common neurologic disorders. Underlying cause of epilepsy is unknown in 60 % of the patients. Toxoplasma gondii is an intracellular parasite which is capable of forming tissue cysts in brain of chronically infected hosts including humans. Some epidemiological studies suggested an association between toxoplasmosis and acquisition of epilepsy. In this study we determined seroprevalence of latent Toxoplasma infection in a population of Iranian epileptic patients. Participants were classified in three groups as Iranian epileptic patients (IEP, n = 414), non-epileptic patients who had other neurologic disorders (NEP, n = 150), and healthy people without any neurologic disorders (HP, n = 63)...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28501456/assessing-age-dependent-susceptibility-to-measles-in-japan
#20
Ryo Kinoshita, Hiroshi Nishiura
BACKGROUND: Routine vaccination against measles in Japan started in 1978. Whereas measles elimination was verified in 2015, multiple chains of measles transmission were observed in 2016. We aimed to reconstruct the age-dependent susceptibility to measles in Japan so that future vaccination strategies can be elucidated. METHODS: An epidemiological model was used to quantify the age-dependent immune fraction using datasets of vaccination coverage and seroepidemiological survey...
June 5, 2017: Vaccine
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