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https://www.readbyqxmd.com/read/28733755/automatic-regional-analysis-of-myocardial-native-t1-values-left-ventricle-segmentation-and-aha-parcellations
#1
Hsiao-Hui Huang, Chun-Yu Huang, Chiao-Ning Chen, Yun-Wen Wang, Teng-Yi Huang
Native T1 value is emerging as a reliable indicator of abnormal heart conditions related to myocardial fibrosis. Investigators have extensively used the standardized myocardial segmentation of the American Heart Association (AHA) to measure regional T1 values of the left ventricular (LV) walls. In this paper, we present a fully automatic system to analyze modified Look-Locker inversion recovery images and to report regional T1 values of AHA segments. Ten healthy individuals participated in the T1 mapping study with a 3...
July 21, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28730704/the-athena-hpv-study-underrepresents-other-high-risk-hpv-genotypes-when-compared-with-a-diverse-new-york-city-population
#2
G Ramos Rivera, S N Khader, S Lajara, K Schlesinger, D Y Goldstein, R C Naeem, M J Suhrland, A S Fox
OBJECTIVE: Persistent infection with oncogenic high risk HPV (hrHPV) types causes virtually all cases of cervical cancer. HPV 16 and 18 have been targeted for individual genotyping and vaccination because of their presence in 71% of invasive cervical cancers worldwide. Montefiore Medical Center, Bronx, New York serves a population known for ethnic and racial diversity. Given this diversity it is possible that HPV genotypes not individually detected by current testing are causing significant disease...
July 21, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28728575/genome-wide-association-study-identifies-a-major-gene-for-beech-bark-disease-resistance-in-american-beech-fagus-grandifolia-ehrh
#3
Irina Ćalić, Jennifer Koch, David Carey, Charles Addo-Quaye, John E Carlson, David B Neale
BACKGROUND: The American Beech tree (Fagus grandifolia Ehrh.), native to eastern North America, is ecologically important and provides high quality wood products. This species is susceptible to beech bark disease (BBD) and is facing high rates of mortality in North America. The disease occurs from an interaction between the woolly beech scale insect (Cryptococcus fagisuga), one of two species of the fungus Neonectria (N. faginata or N. ditissima), and American Beech trees. METHODS: In this case-control genome-wide association study (GWAS), we tested 16 K high quality SNPs using the Affymetrix Axiom 1...
July 20, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28727682/racial-and-ethnic-differences-in-homicides-of-adult-women-and-the-role-of-intimate-partner-violence-united-states-2003-2014
#4
Emiko Petrosky, Janet M Blair, Carter J Betz, Katherine A Fowler, Shane P D Jack, Bridget H Lyons
Homicide is one of the leading causes of death for women aged ≤44 years.* In 2015, homicide caused the death of 3,519 girls and women in the United States. Rates of female homicide vary by race/ethnicity (1), and nearly half of victims are killed by a current or former male intimate partner (2). To inform homicide and intimate partner violence (IPV) prevention efforts, CDC analyzed homicide data from the National Violent Death Reporting System (NVDRS) among 10,018 women aged ≥18 years in 18 states during 2003-2014...
July 21, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28727519/obesity-and-overweight-in-american-indian-and-alaska-native-children-2006-2015
#5
Ann Bullock, Karen Sheff, Kelly Moore, Spero Manson
OBJECTIVES: To estimate obesity and overweight prevalence in American Indian and Alaska Native (AI/AN) children across genders, ages, and geographic regions in the Indian Health Service active clinical population. METHODS: We obtained data from the Indian Health Service National Data Warehouse. At least 184 000 AI/AN children aged 2 to 19 years had body mass index data for each year studied, 2006 to 2015. We calculated body mass index percentiles with the 2000 Centers for Disease Control and Prevention growth charts...
July 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28725396/american-trees-shift-their-niches-when-invading-western-europe-evaluating-invasion-risks-in-a-changing-climate
#6
Etienne Camenen, Annabel J Porté, Marta Benito Garzón
Four North American trees are becoming invasive species in Western Europe: Acer negundo, Prunus serotina, Quercus rubra, and Robinia pseudoacacia. However, their present and future potential risks of invasion have not been yet evaluated. Here, we assess niche shifts between the native and invasive ranges and the potential invasion risk of these four trees in Western Europe. We estimated niche conservatism in a multidimensional climate space using niche overlap Schoener's D, niche equivalence, and niche similarity tests...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28723930/does-culture-create-craving-evidence-from-the-case-of-menstrual-chocolate-craving
#7
Julia M Hormes, Martha A Niemiec
Craving is considered a key characteristic of diverse pathologies, but evidence suggests it may be a culture-bound construct. Almost 50% of American women crave chocolate specifically around the onset of menstruation. Research does not support popular accounts implicating physiological factors in menstrual chocolate craving etiology. We tested the novel hypothesis that greater menstrual craving prevalence in the U.S. is the product of internalized cultural norms. Women of diverse backgrounds (n = 275) reported on craving frequency and triggers and completed validated measures of acculturation...
2017: PloS One
https://www.readbyqxmd.com/read/28723242/interspecific-and-intraspecific-hybrid-epichlo%C3%A3-species-symbiotic-with-the-north-american-native-grass-poa-alsodes
#8
Tatsiana Shymanovich, Nikki D Charlton, Ashleigh M Musso, Jonathan Scheerer, Nadja B Cech, Stanley H Faeth, Carolyn A Young
The endophyte presence and diversity in natural populations of Poa alsodes were evaluated along a latitudinal transect from the southern distribution range in North Carolina to New York. Two distinct Epichloë hybrid taxa were identified from 23 populations. Each taxon could easily be distinguished by polymerase chain reaction (PCR) genotyping with primers designed to mating type genes and alkaloid biosynthesis genes that encode key pathway steps for ergot alkaloids, indole-diterpenes, lolines, and peramine...
June 26, 2017: Mycologia
https://www.readbyqxmd.com/read/28720073/heterogeneity-in-national-u-s-mortality-trends-within-heart-disease-subgroups-2000-2015
#9
Stephen Sidney, Charles P Quesenberry, Marc G Jaffe, Michael Sorel, Alan S Go, Jamal S Rana
BACKGROUND: The long-term downward national U.S. trend in heart disease-related mortality slowed substantially during 2011-2014 before turning upward in 2015. Examining mortality trends in the major subgroups of heart disease may provide insight into potentially more targeted and effective prevention and treatment approaches to promote favorable trajectories. We examined national trends between 2000 and 2015 in mortality attributed to major heart disease subgroups including ischemic heart disease, heart failure, and all other types of heart disease...
July 18, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28715553/validation-of-the-children-s-hospital-of-philadelphia-retinopathy-of-prematurity-chop-rop-model
#10
Gil Binenbaum, Gui-Shuang Ying, Lauren A Tomlinson
Importance: The Children's Hospital of Philadelphia Retinopathy of Prematurity (CHOP ROP) model uses birth weight (BW), gestational age at birth (GA), and weight gain rate to predict the risk of severe retinopathy of prematurity (ROP). In a model development study, it predicted all infants requiring treatment, while greatly reducing the number of examinations compared with current screening guidelines. Objective: To validate the CHOP ROP model in a multicenter cohort that is large enough to obtain a precise estimate of the model's sensitivity for treatment-requiring ROP...
July 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28714599/the-utility-of-empirically-assigning-ancestry-groups-in-cross-population-genetic-studies-of-addiction
#11
Roseann E Peterson, Alexis C Edwards, Silviu-Alin Bacanu, Danielle M Dick, Kenneth S Kendler, Bradley T Webb
BACKGROUND AND OBJECTIVES: Given moderate heritability and significant heterogeneity among addiction phenotypes, successful genome-wide association studies (GWAS) are expected to need very large samples. As sample sizes grow, so can genetic diversity leading to challenges in analyzing these data. Methods for empirically assigning individuals to genetically informed ancestry groups are needed. METHODS: We describe a strategy for empirically assigning ancestry groups in ethnically diverse GWAS data including extensions of principal component analysis (PCA) and population matching through minimum Mahalanobis distance...
July 17, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28712352/national-overview-of-medication-assisted-treatment-for-american-indians-and-alaska-natives-with-substance-use-disorders
#12
Traci Rieckmann, Laurie Moore, Calvin Croy, Gregory A Aarons, Douglas K Novins
OBJECTIVE: American Indians and Alaska Natives (AI/ANs) experience higher rates of substance use disorders and less access to high-quality care compared with other racial-ethnic groups. The objective of this study was to better understand the use of medication-assisted treatment (MAT) of substance use disorders for AI/ANs and barriers to broader implementation. METHODS: Representatives of 192 substance abuse treatment programs completed a survey about their use of MAT...
July 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28709582/the-incidence-of-transfusion-and-associated-risk-factors-in-pelvic-reconstructive-surgery
#13
Lopa K Pandya, Courtney Lynch, Andrew F Hundley, Silpa Nekkanti, Catherine O Hudson
BACKGROUND: Almost 400,000 female pelvic reconstructive operations were performed in 2010 for urinary incontinence and pelvic organ prolapse in the United States, and it is likely that this will continue to increase each year. There is a lack of population-based data evaluating the risk of blood transfusion after urogynecologic procedures. OBJECTIVES: To assess the incidence of blood transfusion related to pelvic reconstructive surgery in a large national surgical quality database and to identify transfusion-associated risk factors...
July 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28700391/human-t-lymphotropic-virus-type-1-infection-and-disease-in-spain
#14
Carmen de Mendoza, Estrella Caballero, Antonio Aguilera, Silvia Requena, Raúl Ortiz de Lejarazu, María Pirón, Rocío González, Ana Jiménez, Lourdes Roc, Ana Treviño, Rafael Benito, Miriam Fernández-Alonso, Aitziber Aguinaga, Carmen Rodríguez, Juan García-Costa, Lidia Blanco, José M Ramos, Enrique Calderón, José M Eirós, Silvia Sauleda, Pablo Barreiro, Vicente Soriano
: Human T-lymphotropic virus type 1 (HTLV-1) infection is a neglected disease despite roughly 15 million people are chronically infected worldwide. Lifelong less than 10% of carriers develop life-threatening diseases, mostly a subacute myelopathy known as tropical spastic paraparesis (TSP) and a lymphoproliferative disorder named adult T-cell leukemia (ATL). HTLV-1 is efficiently transmitted perinatally (breastfeeding), sexually (more from men to women) and parenterally (transfusions, injection drug user (IDU), and transplants)...
July 31, 2017: AIDS
https://www.readbyqxmd.com/read/28696560/overview-of-admixture-mapping
#15
Daniel Shriner
Admixture mapping is a powerful method of gene mapping for diseases or traits that show differential risk by ancestry. Admixture mapping has been applied most often to Americans who trace ancestry to various combinations of Native Americans, Europeans, and West Africans. Recent developments in admixture mapping include improvements in methods and the reference data needed to make inferences about ancestry, as well as extensions of the mapping approach in the framework of linear mixed models. In this unit, the key concepts of admixture mapping are outlined...
July 11, 2017: Current Protocols in Human Genetics
https://www.readbyqxmd.com/read/28696428/growing-the-lost-crops-of-eastern-north-america-s-original-agricultural-system
#16
Natalie G Mueller, Gayle J Fritz, Paul Patton, Stephen Carmody, Elizabeth T Horton
Thousands of years before the maize-based agriculture practiced by many Native American societies in eastern North America at the time of contact with Europeans, there existed a unique crop system only known through archaeological evidence. There are no written or oral records of how these lost crops were cultivated, but several domesticated subspecies have been identified in the archaeological record. Growth experiments and observations of living progenitors of these crops can provide insights into the ancient agricultural system of eastern North America, the role of developmental plasticity in the process of domestication, and the creation and maintenance of diverse landraces under cultivation...
July 5, 2017: Nature Plants
https://www.readbyqxmd.com/read/28693036/association-of-coffee-consumption-with-total-and-cause-specific-mortality-among-nonwhite-populations
#17
Song-Yi Park, Neal D Freedman, Christopher A Haiman, Loïc Le Marchand, Lynne R Wilkens, Veronica Wendy Setiawan
Background: Coffee consumption has been associated with reduced risk for death in prospective cohort studies; however, data in nonwhites are sparse. Objective: To examine the association of coffee consumption with risk for total and cause-specific death. Design: The MEC (Multiethnic Cohort), a prospective population-based cohort study established between 1993 and 1996. Setting: Hawaii and Los Angeles, California. Participants: 185 855 African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites aged 45 to 75 years at recruitment...
July 11, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28690819/molecular-genetic-analysis-of-two-native-desert-palm-genera-washingtonia-and-brahea-from-the-baja-california-peninsula-and-guadalupe-island
#18
Anastasia Klimova, Joseph I Hoffman, Jesus N Gutierrez-Rivera, Jose Leon de la Luz, Alfredo Ortega-Rubio
The complex geological and ecological processes that have generated high levels of biodiversity and endemism in the Baja California Peninsula have been the subject of intensive study. However, relatively little is known about phylogeography of the iconic endemic palm species of this region. We therefore analyzed a total of 2,294 bp of chloroplast and 738 bp of nuclear sequence data in 169 samples of five native palm species from Baja California, Sonora and Guadalupe Island. We found that Washingtonia and Brahea palms had low levels of genetic diversity and were highly structured, with the majority of species and major geographic regions being characterized by distinct haplotypes...
July 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28688850/crop-associated-virus-reduces-the-rooting-depth-of-non-crop-perennial-native-grass-more-than-non-crop-associated-virus-with-known-viral-suppressor-of-rna-silencing-vsr
#19
Carolyn M Malmstrom, Patrick Bigelow, Piotr Trebicki, Anna K Busch, Colleen Friel, Ellen Cole, Heba Abdel-Azim, Colin Phillippo, Helen M Alexander
As agricultural acreage expanded and came to dominate landscapes across the world, viruses gained opportunities to move between crop and wild native plants. In the Midwestern USA, virus exchange currently occurs between widespread annual Poaceae crops and remnant native perennial prairie grasses now under consideration as bioenergy feedstocks. In this region, the common aphid species Rhopalosiphum padi L. (the bird cherry-oat aphid) transmits several virus species in the family Luteoviridae, including Barley yellow dwarf virus (BYDV-PAV, genus Luteovirus) and Cereal yellow dwarf virus (CYDV-RPV and -RPS, genus Polerovirus)...
July 5, 2017: Virus Research
https://www.readbyqxmd.com/read/28688048/susceptibility-background-for-type-2-diabetes-in-eleven-mexican-indigenous-populations-hnf4a-gene-analysis
#20
M A Granados-Silvestre, M G Ortiz-López, J Granados, S Canizales-Quinteros, Rosenda I Peñaloza-Espinosa, C Lechuga, V Acuña-Alonzo, K Sánchez-Pozos, M Menjivar
The genetic risk of developing type 2 diabetes (T2D) increases in parallel with the proportion of Native American ancestry. Mestizo Mexicans have a 70% Native Amerindian genetic background. The T130I polymorphism in the HNF4A gene has been associated with early-onset T2D in mestizo Mexicans. Thus, the aim of the present study was to evaluate the frequency and relationship of the T130I variant in the HNF4A gene with risk factors for developing T2D in eleven indigenous groups from Mexico. In two groups, all exons of the HNF4A gene were directly sequenced; in the remaining the T130I polymorphism was analyzed by restriction fragment length polymorphism...
July 7, 2017: Molecular Genetics and Genomics: MGG
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