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https://www.readbyqxmd.com/read/28457055/short-term-efficacy-of-cbd-enriched-hemp-oil-in-girls-with-dysautonomic-syndrome-after-human-papillomavirus-vaccination
#1
Beniamino Palmieri, Carmen Laurino, Maria Vadalà
BACKGROUND: Cannabidiol (CBD)-based treatments for several diseases, including Tourette's syndrome, multiple sclerosis, epilepsy, movement disorders and glaucoma, are proving to be beneficial and the scientific clinical background of the drug is continuously evolving. OBJECTIVES: To investigate the short-term effect of CBD-enriched hemp oil for relieving symptoms and improving the life quality (QOL) in young girls with adverse drug effects (ADRs) following human papillomavirus (HPV) vaccine...
February 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28448475/formulation-characterization-and-properties-of-hemp-seed-oil-and-its-emulsions
#2
Veronika Mikulcová, Věra Kašpárková, Petr Humpolíček, Leona Buňková
The formulation, characterization, and anticipated antibacterial properties of hemp seed oil and its emulsions were investigated. The oil obtained from the seeds of Cannabis sativa L. in refined and unrefined form was characterized using iodine, saponification, acid values, and gas chromatography, and was employed for the preparation of stable oil-in-water emulsions. The emulsions were prepared using pairs of non-ionic surfactants (Tween, Span). The effects of the emulsification method (spontaneous emulsification vs...
April 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28435268/biocompatible-nanoemulsions-based-on-hemp-oil-and-less-surfactants-for-oral-delivery-of-baicalein-with-enhanced-bioavailability
#3
Juntao Yin, Cuiyu Xiang, Peiqing Wang, Yuyun Yin, Yantao Hou
Baicalein (BCL) possesses high pharmacological activities but low solubility and stability in the intestinal tract. This study aimed to probe the potential of nanoemulsions (NEs) consisting of hemp oil and less surfactants in ameliorating the oral bioavailability of BCL. BCL-loaded NEs (BCL-NEs) were prepared by high-pressure homogenization technique to reduce the amount of surfactants. BCL-NEs were characterized by particle size, entrapment efficiency (EE), in vitro drug release, and morphology. Bioavailability was studied in Sprague-Dawley rats following oral administration of BCL suspensions, BCL conventional emulsions, and BCL-NEs...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28431313/raman-spectroscopy-for-the-characterization-of-different-fractions-of-hemp-essential-oil-extracted-at-130%C3%A2-c-using-steam-distillation-method
#4
Muhammad Asif Hanif, Haq Nawaz, Saima Naz, Rubina Mukhtar, Nosheen Rashid, Ijaz Ahmad Bhatti, Muhammad Saleem
In this study, Raman spectroscopy along with Principal Component Analysis (PCA) is used for the characterization of pure essential oil (pure EO) isolated from the leaves of the Hemp (Cannabis sativa L.,) as well as its different fractions obtained by fractional distillation process. Raman spectra of pure Hemp essential oil and its different fractions show characteristic key bands of main volatile terpenes and terpenoids, which significantly differentiate them from each other. These bands provide information about the chemical composition of sample under investigation and hence can be used as Raman spectral markers for the qualitative monitoring of the pure EO and different fractions containing different active compounds...
July 5, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28240903/flexible-bionanocomposites-from-epoxidized-hemp-seed-oil-thermosetting-resin-reinforced-with-halloysite-nanotubes
#5
Peter S Shuttleworth, Ana M Díez-Pascual, Carlos Marco, Gary Ellis
Hemp seed (Cannabis sativa L.) oil comprises a variety of beneficial unsaturated triglycerides with well-documented nutritional and health benefits. However, it can become rancid over a relatively short time period, leading to increased industrial costs and waste of a valuable product. The development of sustainable polymers is presented as a strategy, where both the presence of unsaturation and peroxide content could be effectively used to alleviate both the waste and financial burden. After the reaction with peroxyacetic acid, the incorporation of halloysite nanotubes (HNTs), and the subsequent thermal curing, without the need for organic solvents or interfacial modifiers, flexible transparent materials with a low glass-transition temperature were developed...
March 8, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28191338/accelerated-burn-wound-closure-in-mice-with-a-new-formula-based-on-traditional-medicine
#6
Mehrnaz Mehrabani, Seyyed Mohsen Seyyedkazemi, Mohammad Hadi Nematollahi, Elham Jafari, Mitra Mehrabani, Mohammad Mehdipour, Zahra Sheikhshoaee, Ali Mandegary
BACKGROUND: A combination of the oils of sesame, hemp, wild pistachio, and walnut has been used for treatment of skin disorders, including wound burns, in some parts of Kerman, Iran. Evaluation of this remedy in the form of a pharmaceutical formulation in animal models can pave the way for its future application in wound burn healing in humans. OBJECTIVES: This experimental study investigated the healing potential of a new formula (NF) based on folk medicine from Iran for the treatment of third degree burns in mice...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28188639/effect-of-unconventional-oilseeds-safflower-poppy-hemp-camelina-on-in-vitro-ruminal-methane-production-and-fermentation
#7
Shaopu Wang, Michael Kreuzer, Ueli Braun, Angela Schwarm
BACKGROUND: Dietary supplementation with oilseeds can reduce methane emission in ruminants, but only a few common seeds have been tested so far. This study tested safflower (Carthamus tinctorius), poppy (Papaver somniferum), hemp (Cannabis sativa), and camelina (Camelina sativa) seeds in vitro using coconut (Cocos nucifera) oil and linseed (Linum usitatissimum) as positive controls. RESULTS: All the tested oilseeds suppressed methane yield (ml g(-1) dry matter, up to 21%) compared to the non-supplemented control when provided at 70 g oil kg(-1) dry matter, and they were as effective as coconut oil...
February 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28160006/performance-and-tissue-fatty-acid-profile-of-broiler-chickens-and-laying-hens-fed-hemp-oil-and-hempomegatm
#8
M Jing, S Zhao, J D House
This study was conducted to determine the effects of hemp oil (HO) and HempOmega (HΩ), an equivalent product to HO, on performance and tissue fatty acid profile of layers and broiler chickens in two separate experiments. In the first experiment, forty 19-wk old Lohmann white laying hens were randomized to 1 of 5 dietary treatments, either a control diet or a control diet supplemented with 4 or 8% hemp oil provided by HO or HΩ, for a period of 6 wk (n = 8/diet). In experiment 2, 150-day-old mixed-sex (75 male; 75 female) Ross 308 chicks were randomly allocated into 5 dietary treatments, a control diet or a control diet supplemented with either 3 or 6% hemp oil provided by HO or HΩ, each with six replicates of 5 chicks for a 21-d feeding period...
June 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/27919534/adsorption-of-acid-extractable-organics-from-oil-sands-process-affected-water-onto-biomass-based-biochar-metal-content-matters
#9
Tazul I Bhuiyan, Jin K Tak, Sebastian Sessarego, Don Harfield, Josephine M Hill
The impact of biochar properties on acid-extractable organics (AEO) adsorption from oil sands process-affected water (OSPW) was studied. Biochar from wheat straw with the highest ash content (14%) had the highest adsorption capacity (0.59 mg/g) followed by biochar from pulp mill sludge, switchgrass, mountain pine, hemp shives, and aspen wood. The adsorption capacity had no obvious trend with surface area, total pore volume, bulk polarity and aromaticity. The large impact of metal content was consistent with the carboxylates (i...
February 2017: Chemosphere
https://www.readbyqxmd.com/read/27471078/limitations-to-the-dutch-cannabis-toleration-policy-assumptions-underlying-the-reclassification-of-cannabis-above-15-thc
#10
Margriet Van Laar, Peggy Van Der Pol, Raymond Niesink
The Netherlands has seen an increase in Δ9-tetrahydrocannabinol (THC) concentrations from approximately 8% in the 1990s up to 20% in 2004. Increased cannabis potency may lead to higher THC-exposure and cannabis related harm. The Dutch government officially condones the sale of cannabis from so called 'coffee shops', and the Opium Act distinguishes cannabis as a Schedule II drug with 'acceptable risk' from other drugs with 'unacceptable risk' (Schedule I). Even in 1976, however, cannabis potency was taken into account by distinguishing hemp oil as a Schedule I drug...
August 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27299295/cannabinoid-poisoning-by-hemp-seed-oil-in-a-child
#11
Matteo Chinello, Salvatore Scommegna, Alison Shardlow, Francesca Mazzoli, Nadia De Giovanni, Nadia Fucci, Paola Borgiani, Cinzia Ciccacci, Anna Locasciulli, Mauro Calvani
We report a case of mild cannabinoid poisoning in a preschool child, after 3-week ingestion of hemp seed oil prescribed by his pediatrician to strengthen his immune system. The patient presented neurological symptoms that disappeared after intravenous hydration. A possible mild withdrawal syndrome was reported after discharge. The main metabolite of Δ-tetrahydrocannabinol was detected in urine, and very low concentration of Δ-tetrahydrocannabinol was detected in the ingested product. This is, as far as we know, the first report of cannabinoid poisoning after medical prescription of hemp seed oil in a preschool child...
May 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27242881/variability-in-seed-traits-in-a-collection-of-cannabis-sativa-l-genotypes
#12
Incoronata Galasso, Roberto Russo, Sergio Mapelli, Elena Ponzoni, Ida M Brambilla, Giovanna Battelli, Remo Reggiani
The seed of Cannabis sativa L. is an expanding source of proteins and oil for both humans and animals. In this study, the proximate composition of a collection of hemp cultivars and accessions of different geographical origins grown under the same conditions for 1 year was analyzed in order to identify potential accessions to improve hemp cultivars. Fatty acids, tocopherols, and antinutritional components, as well as concentrations of crude protein and oil were quantified. The seed oil concentrations varied between 285 and 360 g kg(-1) dry seed (DS), while crude protein ranged between 316 and 356 g kg(-1) dry matter (DM)...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27076277/polyphenolic-compounds-and-antioxidant-activity-of-cold-pressed-seed-oil-from-finola-cultivar-of-cannabis-sativa-l
#13
Antonella Smeriglio, Enza M Galati, Maria T Monforte, Francesco Lanuzza, Valeria D'Angelo, Clara Circosta
The aim of this study was to characterize the polyphenolic compounds and antioxidant activity of cold-pressed seed oil from Finola cultivar of industrial hemp (Cannabis sativa L.). Several methodologies have been employed to evaluate the in vitro antioxidant activity of Finola hempseed oil (FHSO) and both lipophilic (LF) and hydrophilic fractions (HF). The qualitative and quantitative composition of the phenolic fraction of FHSO was performed by HPLC analyses. From the results is evident that FHSO has high antioxidative activity, as measured by DPPH radical (146...
August 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/26439817/variability-toxicity-and-antioxidant-activity-of-eupatorium-cannabinum-hemp-agrimony-essential-oils
#14
Asta Judzentiene, Rasa Garjonyte, Jurga Budiene
CONTENT: Eupatorium cannabinum L. (Asteraceae) is as a potential source of biologically active compounds. The plant is used in traditional medicine for the treatment of diarrhea and livers diseases. OBJECTIVE: The present study provides investigation on pharmacological properties (antioxidant and toxic activities) of essential oils of E. cannabinum, collected from 11 wild populations in Lithuania. MATERIALS AND METHODS: Twenty-two hemp agrimony essential oil samples were prepared by hydrodistillation according to the European Pharmacopoeia, and their chemical composition was determined by GC-FID and GC-MS...
2016: Pharmaceutical Biology
https://www.readbyqxmd.com/read/26365444/alteration-of-delta-6-desaturase-fads2-secretory-phospholipase-a2-spla2-enzymes-by-hot-nature-diet-with-co-supplemented-hemp-seed-evening-primrose-oils-intervention-in-multiple-sclerosis-patients
#15
RANDOMIZED CONTROLLED TRIAL
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Mehrangiz Ebrahimi-Mamaghani, Behzad Baradaran, Elyar Sadeghihokmabad, Somaiyeh Mostafaei, Mohammadali Torbati, Mahtaj Chehreh
BACKGROUND: The effect of nutrition and dietary supplements as environmental factors has been suggested as possible factors affecting both disease risk and progression in on the course of multiple sclerosis with complex genetic-risk profiles. This study was aimed to assess regulation of surface-membrane enzymes such as Delta-6-desaturase (FADS2), secretory Phospholipase A2(sPLA2) by hemp seed and evening primrose oils as well as Hot-natured dietary intervention in relapsing remitting multiple sclerosis (RRMS) patients...
October 2015: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/26057750/fatty-acids-composition-of-vegetable-oils-and-its-contribution-to-dietary-energy-intake-and-dependence-of-cardiovascular-mortality-on-dietary-intake-of-fatty-acids
#16
Jana Orsavova, Ladislava Misurcova, Jarmila Vavra Ambrozova, Robert Vicha, Jiri Mlcek
Characterizations of fatty acids composition in % of total methylester of fatty acids (FAMEs) of fourteen vegetable oils--safflower, grape, silybum marianum, hemp, sunflower, wheat germ, pumpkin seed, sesame, rice bran, almond, rapeseed, peanut, olive, and coconut oil--were obtained by using gas chromatography (GC). Saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA), palmitic acid (C16:0; 4.6%-20.0%), oleic acid (C18:1; 6.2%-71.1%) and linoleic acid (C18:2; 1.6%-79%), respectively, were found predominant...
2015: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/25977051/effect-directed-analysis-of-cold-pressed-hemp-flax-and-canola-seed-oils-by-planar-chromatography-linked-with-bio-assays-and-mass-spectrometry
#17
Sue-Siang Teh, Gertrud E Morlock
Cold-pressed hemp, flax and canola seed oils are healthy oils for human consumption as these are rich in polyunsaturated fatty acids and bioactive phytochemicals. However, bioactive information on the food intake side is mainly focused on target analysis. For more comprehensive information with regard to effects, single bioactive compounds present in the seed oil extracts were detected by effect-directed assays, like bioassays or an enzymatic assay, directly linked with chromatography and further characterized by mass spectrometry...
November 15, 2015: Food Chemistry
https://www.readbyqxmd.com/read/25745251/effect-of-ultrasound-pre-treatment-of-hemp-cannabis-sativa-l-seed-on-supercritical-co2-extraction-of-oil
#18
C Da Porto, A Natolino, D Decorti
Ultrasound pre-treatment of intact hemp seeds without any solvent assistance was carried out for 10, 20 and 40 min prior to SCCO2 extraction at 40 °C, 300 bar and 45 kg CO2/kg feed. Sonication time effect on SC-CO2 extraction was investigated by the extraction kinetics. The maximum extraction yield was estimated to be 24.03 (% w/w) after 10 min of ultrasonic pre-treatment. The fatty acid compositions of the oils extracted by SC-CO2 without and with ultrasound pre-treatments was analyzed using gas chromatography...
March 2015: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/25704610/stability-of-cosmetic-emulsion-containing-different-amount-of-hemp-oil
#19
M Kowalska, M Ziomek, A Żbikowska
OBJECTIVE: The aim of the study was to determine the optimal conditions, that is the content of hemp oil and time of homogenization to obtain stable dispersion systems. METHODS: For this purpose, six emulsions were prepared, their stability was examined empirically and the most correctly formulated emulsion composition was determined using a computer simulation. Variable parameters (oil content and homogenization time) were indicated by the optimization software based on Kleeman's method...
August 2015: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/25453518/activity-of-liver-enzymes-in-multiple-sclerosis-patients-with-hot-nature-diet-and-co-supplemented-hemp-seed-evening-primrose-oils-intervention
#20
RANDOMIZED CONTROLLED TRIAL
Soheila Rezapour-Firouzi, Seyed Rafie Arefhosseini, Mehrangiz Ebrahimi-Mamaghani, Behzad Baradaran, Elyar Sadeghihokmabad, Mohammadali Torbati, Somaiyeh Mostafaei, Mahtaj Chehreh, Fatemeh Zamani
BACKGROUND: It is unknown whether diets with a high dietary total antioxidant capacity (TAC) can modify oxidative stress, low-grade inflammation, or liver dysfunction, all of which are risk factors for multiple sclerosis disease. This study assesses alanine amino-transferase (ALT), aspartate-aminotransferase (AST) and gamma-glutamyl transferase (GGT) activities in MS patients treated with co-supplemented hemp seed and evening primrose oils as well as Hot-nature diet and the therapeutic potential this intervention...
December 2014: Complementary Therapies in Medicine
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