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https://www.readbyqxmd.com/read/28721991/angiogenesis-concept-in-odontogenic-keratocyst-a-comparative-study
#1
Donia Sadri, Fatemeh Shahsavari, Sareh Farhadi, Zahra Shahabi, Zahra Mehran
CONTEXT: Recent reports have indicated that angiogenesis possibly affects the biologic behavior of the lesions. AIM: Given the different clinical behaviors of odontogenic keratocyst (OKC), the present study was undertaken to evaluate the concept of angiogenesis in pathogenesis and clinical behavior of OKC. SETTING AND DESIGN: This experimental study was carried out on 22 and 24 samples of OKCs and dentigerous cysts (DCs), respectively. METHODS: Immunohistochemical staining was approached using CD34 and vascular endothelial growth factor (VEGF) antibodies...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28706783/the-anecdote-of-viral-etiopathogenia-in-ameloblastoma-and-odontogenic-keratocyst-why-don-t-we-let-it-go
#2
Bacem A E O Khalele
BACKGROUND: Ameloblastoma (AM) and odontogenic Keratocyst (OKC) are destructive odontogenic lesions of the gnathion. Although their exact pathogeneses are not yet totally understood, the viral etiopathogenesis in AM and KCOT has been proposed. True to syndromic keratocystic odontogenic tumor (sKCOT) and non-syndromic OKC is the high recurrence rate. OBJECTIVES: Given that shared pathways trailed by AM and by sKCOT/OKC have been suggested, this study, however, contrasts the expression of AM and OKC for viral antibodies...
May 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28700827/compatible-rhizosphere-competent-microbial-consortium-add-value-to-nutritional-quality-in-edible-parts-of-chickpea
#3
Sudheer KUmar Yadav, Surendra Singh, Harikesh Bahadur Singh, Birinchi Kumar Sarma
Chickpea is used as a high energy and protein source in human and livestock's diets. Moreover, chickpea straw can be used as alternative of forage in ruminant diets. The present study evaluates the effect of beneficial microbial inoculation on enhancing the nutritional values in edible parts of chickpea. Two rhizosphere competent compatible microbes (Pseudomonas fluorescens OKC and Trichoderma asperellum T42) were selected and applied to seeds either individually or in consortium before sowing. Chickpea seeds treated with the microbes showed enhanced plant growth (88...
July 12, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28680851/squamous-cell-carcinoma-arising-within-a-maxillary-odontogenic-keratocyst-a-rare-occurrence
#4
Elnaz Jalali, Elie M Ferneini, Kandasamy Rengasamy, Aditya Tadinada
Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC...
June 2017: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/28584604/p53-protein-expression-in-dental-follicle-dentigerous-cyst-odontogenic-keratocyst-and-inflammatory-subtypes-of-cysts-an-immunohistochemical-study
#5
Mashhadiabbas Fatemeh, Arab Sepideh, Bagheri Seyedeh Sara, Mahdavi Nazanin
OBJECTIVES: An odontogenic keratocyst (OKC) is a developmental odontogenic cyst with aggressive clinical behavior. This cyst shows a different growth mechanism from the more common dentigerous cyst and now has been renamed as a keratocystic odontogenic tumor (KCOT). Inflammation can assist tumor growth via different mechanisms including dysregulation of the p53 gene. This study aims to assess and compare the expression of tumor suppressor gene p53 in inflamed and non-inflamed types of OKC and dentigerous cyst...
May 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28512274/glucose-transporter-1-expression-in-odontogenic-keratocyst-dentigerous-cyst-and-ameloblastoma-an-immunohistochemical-study
#6
Alokenath Bandyopadhyay, Abikshyeet Panda, Shyam S Behura, Sujatha Ramachandra, Kailash C Dash, Pallavi Mishra
INTRODUCTION: An array of odontogenic lesions manifest in the maxillofacial region with variable presentations. The biological behavior of lesions, such as odontogenic keratocyst (OKC), dentigerous cyst (DC), and ameloblastoma (AM) always invite debate. Glucose transporter 1 (GLUT-1) is proven to be an indicator of metabolic behavior of several benign and malignant neoplasms. AIM: The purpose of this study was to evaluate the expression of GLUT-1 in OKC, DC, and AM to understand their metabolic behavior...
May 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28489259/molecular-alterations-in-odontogenic-keratocysts-as-potential-therapeutic-targets
#7
REVIEW
Carolina Cavalieri Gomes, Letícia Martins Guimarães, Marina Gonçalves Diniz, Ricardo Santiago Gomez
The odontogenic keratocyst (OKC) is a cystic lesion, lined by uniformly-thickened parakeratinized epithelium. Some lesions are large and tend to recur after surgical treatment. The neoplastic nature of OKCs remains a matter of dispute. It is known that some sporadic OKCs harbor PTCH1 mutations, and via the dissection of cyst epithelium, these mutations were demonstrated to occur much more frequently than previously thought. In addition to the classical PTCH1 mutations, Hedgehog pathway disturbance and Bcl-2 protein overexpression, as detected via genome-wide expression analysis of OKCs, have been published...
May 10, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28303123/trichoderma-asperellum-t42-and-pseudomonas-fluorescens-okc-enhances-resistance-of-pea-against-erysiphe-pisi-through-enhanced-ros-generation-and-lignifications
#8
Jai S Patel, Ravindra N Kharwar, Harikesh B Singh, Ram S Upadhyay, Birinchi K Sarma
Plant signaling mechanisms are not completely understood in plant-fungal biotrophic pathogen interactions. Further how such interactions are influenced by compatible rhizosphere microbes are also not well-studied. Therefore, we explored the pea-Erysiphe pisi (obligate biotroph) system to understand the interaction and applied compatible rhizospheric bio-agents Trichoderma asperellum (T42) and Pseudomonas fluorescens (OKC) singly or in combination to assess their influence on the host while under the pathogen challenge...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28280759/immunohistochemical-comparison-of-the-expression-of-cd34-and-cd105-in-odontogenic-keratocyst-and-dentigerous-cyst
#9
Shokoofeh Jamshidi, Massoumeh Zargaran, Ghodratollah Roshanaei, Fatemeh Hadadi, Ali Dehghani Nazhvani
STATEMENT OF THE PROBLEM: Odontogenic keratocyst (OKC) is a developmental odontogenic cyst with specific histopathological features, high recurrence rate, and aggressive clinical behavior. Angiogenesis might be considered as an important factor for the growth, expansion, and distribution of this lesion. PURPOSE: The aim of the present study was to determine the mean vascular densities (MVD) of OKCs and dentigerous cysts to evaluate their relationship with the biologic behavior of these lesions...
March 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28089087/prevalence-profile-of-odontogenic-cysts-and-tumors-on-brazilian-sample-after-the-reclassification-of-odontogenic-keratocyst
#10
Filipe Jaeger, Mariana Saturnino de Noronha, Maiza Luiza Vieira Silva, Márcio Bruno Figueiredo Amaral, Soraya de Mattos Carmago Grossmann, Martinho Campolina Rebello Horta, Paulo Eduardo Alencar de Souza, Maria Cássia Ferreira de Aguiar, Ricardo Alves Mesquita
PURPOSE: The aim of this study was to evaluate the impact of the reclassification of odontogenic keratocyst (OKC) as a tumor on the prevalence profile of odontogenic cysts (OCs) and odontogenic tumors (OTs). STUDY DESIGN: Two referral Oral and Maxillofacial Pathology services in Brazil were evaluated. All cases diagnosed as OCs or OTs were selected and classified according to the 1992 WHO-classification (cases before 2005 WHO classification of tumors excluding OKC) and the 2005 WHO classification of tumors, going forward including cases of odontogenic keratocyst tumor (KCOT)...
December 18, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28063998/inhibiting-ros-nf-%C3%AE%C2%BAb-dependent-autophagy-enhanced-brazilin-induced-apoptosis-in-head-and-neck-squamous-cell-carcinoma
#11
Zhi-Jing He, Fei-Ya Zhu, Shi-Sheng Li, Liang Zhong, Hong-Yu Tan, Kai Wang
Autophagy modulation has been considered a potential therapeutic strategy for head and neck squamous cell carcinoma (HNSCC). A previous study confirmed that brazilin might possess significant anti-carcinogenic activity. However, whether brazilin induces autophagy and its roles in cell death in HNSCC are still unclear. In this study, we have shown that brazilin induced significant apoptosis in the Cal27 HNSCC cell line but not in oral keratinocyte cell line (OKC). In addition to showing apoptosis induction, we demonstrated the brazilin-induced autophagic response in the Cal27 cells, as evidenced by the formation of GFP-LC3 puncta, and also showed the upregulation of LC3-II and Beclin-1...
March 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28038841/discontinuation-of-orthokeratology-on-eyeball-elongation-doee
#12
RANDOMIZED CONTROLLED TRIAL
P Cho, S W Cheung
PURPOSE: To evaluate and compare changes in axial elongation, over a 14-month period, in subjects who discontinued and then resumed ortho-k lens wear with those who continued to wear their lenses or spectacles following a 2-year myopia control study. METHOD: This single masked, prospective study recruited subjects who had just completed a 2-year myopia control study. Ortho-k subjects were classified as Group OKc, in which subjects continued ortho-k lens wear for the duration of the study; or Group OKd in which subjects discontinued lens wear for seven months and wore single-vision spectacles (Phase I) and then resumed ortho-k lens wear for another seven months (Phase II)...
April 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27992735/morphological-classification-of-odontogenic-keratocysts-using-bouligand-minkowski-fractal-descriptors
#13
Joao B Florindo, Odemir M Bruno, Gabriel Landini
The Odontogenic keratocyst (OKC) is a cystic lesion of the jaws, which has high growth and recurrence rates compared to other cysts of the jaws (for instance, radicular cyst, which is the most common jaw cyst type). For this reason OKCs are considered by some to be benign neoplasms. There exist two sub-types of OKCs (sporadic and syndromic) and the ability to discriminate between these sub-types, as well as other jaw cysts, is an important task in terms of disease diagnosis and prognosis. With the development of digital pathology, computational algorithms have become central to addressing this type of problem...
February 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27843260/gorlin-goltz-syndrome-a-rare-case-report-of-a-11-year-old-child
#14
Sandeep Tandon, Yashwant Chauhan, Meenakshi Sharma, Manish Jain
Gorlin-Goltz Syndrome, also known as nevoid basal cell carcinoma syndrome (NBCCS), is an autosomal dominant trait caused due to mutations in the patched tumor suppressor gene (PTCH) gene found on the long arm of chromosome 9. The syndrome is characterized by the presence of odontogenic keratocysts (OKCs), basal cell carcinomas, and skeletal malformations. Early diagnosis of the syndrome can be done by pedodontist as OKC is one of the early manifestations of the syndrome. Early diagnosis and treatment is important for long-term prognosis of the syndrome by reducing the severity of cutaneous carcinomas and deformities due to jaw cyst...
July 2016: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27630961/a-comparative-analysis-of-cytokeratin-18-and-19-expressions-in-odontogenic-keratocyst-dentigerous-cyst-and-radicular-cyst-with-a-review-of-literature
#15
Vikas Parshottam Bhakhar, Vandana Sandip Shah, Mohsin Jiva Ghanchi, Sandesh Sachchidanand Gosavi, Himanshu Mahesh Srivastava, Nivedita Javahir Pachore
INTRODUCTION: Odontogenic cysts viz Odontogenic Keratocyst (OKC), Dentigerous Cyst (DC) and Radicular Cyst (RC) occur commonly in the oral and maxillofacial region. Cytokeratin (CK) expression studies have been done to evaluate diagnostic accuracy, role in pathogenesis, elucidate behaviour and role in treatment protocols. However, variations have been reported in the expression of CK patterns in these odontogenic cysts, which could be due to the lack of standardization of laboratory techniques...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27621276/dentigerous-cyst-and-ameloblastoma-of-the-jaws
#16
Andrew W Barrett, Kenneth J Sneddon, John V Tighe, Aakshay Gulati, Laurence Newman, Jeremy Collyer, Paul M Norris, Darryl M Coombes, Michael J Shelley, Brian S Bisase, Rachael D Liebmann
AIM: To determine how many ameloblastomas were misdiagnosed as dentigerous cysts (DCs) by correlating the radiological and histopathological features of a series of both entities. METHODS AND RESULTS: Histopathology reports and radiological imaging of 135 DCs and 43 ameloblastomas were reviewed. Any clinical or radiological feature that suggested that the diagnosis of DC was wrong-for example, absence of an unerupted tooth-prompted review of the original histology...
April 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27342002/three-dimensional-scapular-kinematics-during-open-and-closed-kinetic-chain-movements-in-asymptomatic-and-symptomatic-subjects
#17
Elif Turgut, Øyvind Pedersen, Irem Duzgun, Gul Baltaci
The combination of open kinetic chain (OKC) and closed kinetic chain (CKC) exercises is commonly recommended in shoulder rehabilitation, aiming at improving strength and sport-specific performance. This study aimed to investigate the three-dimensional (3-D) scapular kinematics and bilateral symmetry of scapular motion during dynamic OKC and CKC movements in asymptomatic and symptomatic shoulders. Fifty subjects with unilateral shoulder pain (symptomatic subjects diagnosed with subacromial impingement syndrome, n=20) or without shoulder pain during active shoulder elevation (asymptomatic subjects, n=30) participated in the study...
September 6, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27188081/oda-member-martha-garzon-okc
#18
(no author information available yet)
No abstract text is available yet for this article.
March 2016: Journal—Oklahoma Dental Association
https://www.readbyqxmd.com/read/27092213/immunohistochemical-evaluation-of-myofibroblast-density-in-odontogenic-cysts-and-tumors
#19
Maryam Kouhsoltani, Monireh Halimi, Golchin Jabbari
Background. The aim of this study was to investigate myofibroblast (MF) density in a broad spectrum of odontogenic cysts and tumors and the relation between the density of MFs and the clinical behavior of these lesions. Methods. A total of 105 cases of odontogenic lesions, including unicystic ameloblastoma (UAM), solid ameloblastoma (SA), odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC) (15 for each category), and odontogenic myxoma (OM), adenomatoid odontogenic tumor (AOT), calcifying odontogenic cyst (COC) (10 for each category), were immunohistochemically stained with anti-α-smooth muscle actin antibody...
2016: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/27076824/comparison-of-immunohistochemical-expression-of-cd10-in-keratocystic-odontogenic-tumor-and-ameloblastoma
#20
Elham Hormozi, Vahid Nourollahi Fard, Mohammad Ali Naseri, Nima Haghighat Jahromi, Forooz Keshani
BACKGROUND: Odontogenic keratocyst (OKC), also called keratocystic odontogenic tumor (KCOT), is a developmental lesion which should be carefully monitored and it exhibits development mechanisms and biologic behaviors different from those of other more common lesions such as dentigerous and radicular cysts. CD10 antigen is a cell surface metalloendopeptidase, which inactivates various peptides that are physiologically active. Studies have shown that increase in the expression of CD10 in the stromal cells helps the progression of the tumor...
March 2016: Dental Research Journal
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