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https://www.readbyqxmd.com/read/27843260/gorlin-goltz-syndrome-a-rare-case-report-of-a-11-year-old-child
#1
Sandeep Tandon, Yashwant Chauhan, Meenakshi Sharma, Manish Jain
: Gorlin-Goltz Syndrome, also known as nevoid basal cell carcinoma syndrome (NBCCS), is an autosomal dominant trait caused due to mutations in the patched tumor suppressor gene (PTCH) gene found on the long arm of chromosome 9. The syndrome is characterized by the presence of odontogenic keratocysts (OKCs), basal cell carcinomas, and skeletal malformations. Early diagnosis of the syndrome can be done by pedodontist as OKC is one of the early manifestations of the syndrome. Early diagnosis and treatment is important for long-term prognosis of the syndrome by reducing the severity of cutaneous carcinomas and deformities due to jaw cyst...
July 2016: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27630961/a-comparative-analysis-of-cytokeratin-18-and-19-expressions-in-odontogenic-keratocyst-dentigerous-cyst-and-radicular-cyst-with-a-review-of-literature
#2
Vikas Parshottam Bhakhar, Vandana Sandip Shah, Mohsin Jiva Ghanchi, Sandesh Sachchidanand Gosavi, Himanshu Mahesh Srivastava, Nivedita Javahir Pachore
INTRODUCTION: Odontogenic cysts viz Odontogenic Keratocyst (OKC), Dentigerous Cyst (DC) and Radicular Cyst (RC) occur commonly in the oral and maxillofacial region. Cytokeratin (CK) expression studies have been done to evaluate diagnostic accuracy, role in pathogenesis, elucidate behaviour and role in treatment protocols. However, variations have been reported in the expression of CK patterns in these odontogenic cysts, which could be due to the lack of standardization of laboratory techniques...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27621276/dentigerous-cyst-and-ameloblastoma-of-the-jaws-correlating-the-histopathological-and-clinicoradiological-features-avoids-a-diagnostic-pitfall
#3
Andrew W Barrett, Kenneth J Sneddon, John V Tighe, Aakshay Gulati, Laurence Newman, Jeremy Collyer, Paul M Norris, Darryl M Coombes, Michael J Shelley, Brian S Bisase, Rachael D Liebmann
Aim To determine how many ameloblastomas were misdiagnosed as dentigerous cysts (DCs) by correlating the radiological and histopathological features of a series of both entities. Methods and results Histopathology reports and radiological imaging of 135 DCs and 43 ameloblastomas were reviewed. Any clinical or radiological feature that suggested that the diagnosis of DC was wrong-for example, absence of an unerupted tooth-prompted review of the original histology. A total of 34 cases coded as DC at diagnosis were excluded; in the remaining 101 patients, the clinicoradiological and histopathological features were consistent with DC in 96 (95...
September 12, 2016: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27342002/three-dimensional-scapular-kinematics-during-open-and-closed-kinetic-chain-movements-in-asymptomatic-and-symptomatic-subjects
#4
Elif Turgut, Øyvind Pedersen, Irem Duzgun, Gul Baltaci
The combination of open kinetic chain (OKC) and closed kinetic chain (CKC) exercises is commonly recommended in shoulder rehabilitation, aiming at improving strength and sport-specific performance. This study aimed to investigate the three-dimensional (3-D) scapular kinematics and bilateral symmetry of scapular motion during dynamic OKC and CKC movements in asymptomatic and symptomatic shoulders. Fifty subjects with unilateral shoulder pain (symptomatic subjects diagnosed with subacromial impingement syndrome, n=20) or without shoulder pain during active shoulder elevation (asymptomatic subjects, n=30) participated in the study...
September 6, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27188081/oda-member-martha-garzon-okc
#5
(no author information available yet)
No abstract text is available yet for this article.
March 2016: Journal—Oklahoma Dental Association
https://www.readbyqxmd.com/read/27092213/immunohistochemical-evaluation-of-myofibroblast-density-in-odontogenic-cysts-and-tumors
#6
Maryam Kouhsoltani, Monireh Halimi, Golchin Jabbari
Background. The aim of this study was to investigate myofibroblast (MF) density in a broad spectrum of odontogenic cysts and tumors and the relation between the density of MFs and the clinical behavior of these lesions. Methods. A total of 105 cases of odontogenic lesions, including unicystic ameloblastoma (UAM), solid ameloblastoma (SA), odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC) (15 for each category), and odontogenic myxoma (OM), adenomatoid odontogenic tumor (AOT), calcifying odontogenic cyst (COC) (10 for each category), were immunohistochemically stained with anti-α-smooth muscle actin antibody...
2016: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/27076824/comparison-of-immunohistochemical-expression-of-cd10-in-keratocystic-odontogenic-tumor-and-ameloblastoma
#7
Elham Hormozi, Vahid Nourollahi Fard, Mohammad Ali Naseri, Nima Haghighat Jahromi, Forooz Keshani
BACKGROUND: Odontogenic keratocyst (OKC), also called keratocystic odontogenic tumor (KCOT), is a developmental lesion which should be carefully monitored and it exhibits development mechanisms and biologic behaviors different from those of other more common lesions such as dentigerous and radicular cysts. CD10 antigen is a cell surface metalloendopeptidase, which inactivates various peptides that are physiologically active. Studies have shown that increase in the expression of CD10 in the stromal cells helps the progression of the tumor...
March 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27050804/clinicopathologic-features-associated-with-recurrence-of-the-odontogenic-keratocyst-a-cohort-retrospective-analysis
#8
Joanna Farias Cunha, Carolina Cavalieri Gomes, Ricardo Alves de Mesquita, Eugênio Marcos Andrade Goulart, Wagner Henriques de Castro, Ricardo Santiago Gomez
OBJECTIVE: The aim of this study was to evaluate the influence of clinical, radiographic, surgical and histopathologic parameters in the recurrence of disease in a series of odontogenic keratocysts (OKCs). STUDY DESIGN: The sample comprised 24 sporadic OKC lesions from 24 patients. All patients had no previous treatment history and were treated by the same surgeon using a uniform treatment protocol (enucleation with peripheral ostectomy preceded or not preceded by decompression)...
June 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/27011939/syndromic-odontogenic-keratocyst-a-case-report-and-review-of-literature
#9
Fazil Arshad
Odontogenic keratocysts (OKCs) may occur in two different forms, either as solitary (nonsyndromic OKCs) or as multiple OKCs (syndromic OKCs). Multiple OKCs usually occur as one of the findings in Gorlin-Goltz syndrome with other features such as skin carcinomas and rib, eye, and neurologic abnormalities. We report a rare case of Gorlin-Goltz syndrome in a 20-year-old male patient who presented with a slow growing swelling on lower right and left back teeth region since 2 months. Apart from these, other findings were frontal bossing, depressed nasal bridge, ocular hypertelorism, prominent supra orbital ridge, and mild mandibular prognathism...
January 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/26980976/primary-intraosseous-squamous-cell-carcinoma-in-odontogenic-keratocyst-a-rare-entity
#10
Chitrapriya Saxena, Pooja Aggarwal, Vijay Wadhwan, Vishal Bansal
Squamous cell carcinoma (SCC) arising from the wall of an odontogenic cyst (also known as primary intraosseous carcinoma) is a rare tumor which occurs only in jaw bones. This tumor was first described by Loos in 1913 as a central epidermoid carcinoma of the jaw. Primary intraosseous carcinomas (PIOC) may theoretically arise from the lining of an odontogenic cyst or de novo from presumed odontogenic cell rests. According to the new histological classification of tumors of the World Health Organization, odontogenic keratocyst is nowadays considered a specific odontogenic tumor and the PIOC derived from it is considered as a specific entity which is different from other PIOCs derived from the odontogenic cysts...
September 2015: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/26962343/delayed-diagnosis-of-gorlin-syndrome-learning-from-mistakes
#11
Subramaniyan Ramanathan, Devendra Kumar, Mahmoud Al Heidous, Yegu Palaniappan
Gorlin syndrome (GS) is a rare inherited multisystem disorder with predisposition to basal cell carcinomas and various other neoplasms. Characteristic features include falx calcification, multiple odontogenic keratocysts (OKCs), early onset medulloblastoma, craniofacial and skeletal malformations, cardiac and ovarian fibroma. We present a case of GS in a 9-year-old girl with recurrent dental infections which was overlooked for 8 years. Diagnosis was finally suggested by the incidental detection of multiple OKCs and ovarian fibromas on follow-up magnetic resonance imaging performed for surveillance of previous operated brain tumor...
October 2015: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/26863374/a-single-session-of-open-kinetic-chain-movements-emphasizing-speed-improves-speed-of-movement-and-modifies-postural-control-in-stroke
#12
Vicki L Gray, Tanya D Ivanova, S Jayne Garland
Little attention has been given to training speed of movement, even though functional activities require quick submaximal contractions. Closed kinetic chain (CKC) exercises are considered more functional; however, the best method for training speed is not known. A single bout of open kinetic chain (OKC) exercises emphasizing speed was performed to determine whether movement velocity and muscle activation would improve in a single session and whether the improvements transfer to a physiological balance task...
2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/26793609/immunohistochemical-assessment-of-mast-cells-and-small-blood-vessels-in-dentigerous-cyst-odontogenic-keratocyst-and-periapical-cyst
#13
Maryam Kouhsoltani, Monir Moradzadeh Khiavi, Golshan Jamali, Samira Farnia
PURPOSE: The aim of this study was to verify the density of mast cells (MCs) and microvessels in odontogenic cysts. Furthermore, the correlation between MCs and microvessels was evaluated to assess the contribution of MCs to angiogenesis and growth of odontogenic cysts. This approach may be a basis for the development of future pharmaceuticals addressed to MCs performance to manage odontogenic cysts. To our knowledge, no study investigating the correlation between MCs and microvessels has been performed to date...
December 2015: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/26692930/stat3-is-a-key-pathway-in-primary-intraosseous-squamous-cell-carcinoma-arising-from-an-odontogenic-keratocyst
#14
Ling Zhang, Shu-Li Liu, Wei-Min Ye, Jing Zheng
PURPOSE: Primary intraosseous squamous cell carcinoma (PIOSCC) arising within an odontogenic keratocyst (OKC) is rare malignancy, entailing a poor prognosis for delayed diagnosis. The number of reports concerning this entity is extremely small. The aim of this study is to present the clinical and pathologic characteristics of PIOSCC and investigate its pathogenesis. MATERIALS AND METHODS: This study describes three patients with mandibular PIOSCC derived from an OKC over a seven-year period, each of which suffering from decompression in mandible...
2015: American Journal of Translational Research
https://www.readbyqxmd.com/read/26638715/primary-intraosseous-squamous-cell-carcinoma-arising-in-an-odontogenic-keratocyst-previously-treated-with-marsupialization-case-report-and-immunohistochemical-study
#15
Marisol Martínez-Martínez, Adalberto Mosqueda-Taylor, Wilson Delgado-Azañero, Alicia Rumayor-Piña, Oslei Paes de Almeida
A rare case of primary intraosseous squamous cell carcinoma arising in an odontogenic keratocyst (OKC) is presented here, with the clinical and histologic features of the first biopsy showing characteristics of OKC and the second biopsy disclosing a squamous cell carcinoma. Immunoprofile of this case was compared with five cases of classical OKC by using cytokeratins CK5, CK14, and CK19, CD138, p63, Ki-67, p53, and bcl-2. Classic OKCs showed expected positivity, mainly in the basal and/or suprabasal layers with most antibodies, except for p53, which was negative, whereas the present case showed irregular positivity in all layers, indicating that this can be useful for differential diagnosis and suggesting a possible role in malignant transformation into primary intraosseous squamous cell carcinoma...
April 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/26434831/expression-of-bcl-2-in-primary-and-recurrent-odontogenic-keratocysts-in-comparison-with-other-odontogenic-lesions
#16
Iram Naz, Muhammad Khurram Mahmood, Abdul Hannan Nagi
PURPOSE: To determine the biological behaviour of common odontogenic cystic lesions by analysing and comparing bcl-2 expression amongst them. MATERIALS AND METHODS: Our study covered 90 formalin fixed paraffin embedded tissue samples: 26 primary cases each of radicular cysts (RC), dentigerous cysts (DC) and odontogenic keratocysts (OKC) and 12 of recurrent OKCs. Bcl-2 expression was analysed immunohistochemically and data analysis was accomplished using SPSS version 17...
2015: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/26357548/diagnostic-factors-of-odontogenic-cysts-in-iranian-population-a-retrospective-study-over-the-past-two-decades
#17
Hassan Mohajerani, Mohammad Esmaeelinejad, Siamak Sabour, Farzad Aghdashi, Nima Dehghani
BACKGROUND: Early diagnosis of odontogenic cysts due to their silent progression is always a challenging problem for clinicians. OBJECTIVES: The current study aimed to evaluate the frequency of odontogenic cysts and related factors in a selected Iranian population. PATIENTS AND METHODS: The current cross-sectional study was conducted on 312 patients' recorded data in Taleghani Hospital, Tehran, Iran, from April 1993 to December 2013. All related data were extracted from the records and categorized in tables...
June 2015: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/26225044/keratocystic-odontogenic-tumor-kcot-okc-clinical-guidelines-for-resection
#18
Gary Warburton, Amro Shihabi, Robert A Ord
PURPOSE: There is no clinical consensus for the treatment of Keratocystic Odontogenic Tumor (KCOT). KCOTs are regarded as benign aggressive tumors and resection is usually considered as a last option. We review the clinical indications for resection based on a case series. METHODS: This is a retrospective study of patients with KCOT treated in a single unit over 17 years. Eighty patients were identified, of which 12 (15 %) underwent resection. The remaining 68 patients were managed by enucleation and curettage, enucleation with peripheral ostectomy, or decompression with secondary enucleation...
September 2015: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/25978466/classification-of-tree-species-in-overstorey-canopy-of-subtropical-forest-using-quickbird-images
#19
Chinsu Lin, Sorin C Popescu, Gavin Thomson, Khongor Tsogt, Chein-I Chang
This paper proposes a supervised classification scheme to identify 40 tree species (2 coniferous, 38 broadleaf) belonging to 22 families and 36 genera in high spatial resolution QuickBird multispectral images (HMS). Overall kappa coefficient (OKC) and species conditional kappa coefficients (SCKC) were used to evaluate classification performance in training samples and estimate accuracy and uncertainty in test samples. Baseline classification performance using HMS images and vegetation index (VI) images were evaluated with an OKC value of 0...
2015: PloS One
https://www.readbyqxmd.com/read/25948985/desmosomes-a-light-microscopic-and-ultrastructural-analysis-of-desmosomes-in-odontogenic-cysts
#20
Pratima Raju, Vijay Wadhwan, Minal S Chaudhary
INTRODUCTION: Desmosomes together with adherens junctions represent the major adhesive cell-cell junctions of epithelial cells. Any damage to these junctions leads to loss of structural balance. AIM: The present study was designed to analyze the desmosomal junctions in different odontogenic cysts and compare them with their corresponding hematoxylin and eosin (H and E)   stained sections. MATERIALS AND METHODS: Ten cases each of odontogenic keratocyst (OKC), dentigerous cysts (DCs), radicular cysts (RCs) and normal mucosa were stained with hematoxylin and eosin...
September 2014: Journal of Oral and Maxillofacial Pathology: JOMFP
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