Xiangdong Kong, Lei Wang, Guoyuan Li, Xinhua Qu, Jialin Niu, Tingting Tang, Kerong Dai, Guangyin Yuan, Yongqiang Hao
In this work, the in vivo biocompatibility and biodegradation behavior of Mg-Nd-Zn-Zr alloy (denoted as JDBM) screws were studied using a goat femoral condyle fracture model. Blood analysis indicates that the liver and kidney functions of goats were not affected by JDBM, JDBM coated with brushite (denoted as JDBM-DCPD) and PLA implants. Radiographic analysis shows that JDBM-DCPD screw has lower degradation rate than JDBM. Histological images show that compared with PLA, JDBM and JDBM-DCPD show superior effect to promote more new bone formation...
May 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications