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https://www.readbyqxmd.com/read/28210838/urinary-ngal-deficiency-in-recurrent-urinary-tract-infections
#1
Catherine S Forster, Kathryn Johnson, Viral Patel, Rebecca Wax, Nancy Rodig, Jonathan Barasch, Richard Bachur, Richard S Lee
INTRODUCTION: Children with recurrent urinary tract infections (rUTI) often show no identifiable cause of their infections. Neutrophil gelatinase-associated lipocalin (NGAL) is known to be upregulated within the uroepithelium and kidney of patients with UTI and exhibits a localized bacteriostatic effect through iron chelation. We hypothesize that some patients with rUTI without an identifiable cause of their recurrent infections have locally deficient NGAL production. We therefore explored whether a lack of NGAL production may be a factor in the pathogenesis of rUTI...
February 16, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28208985/pattern-of-inpatient-dermatology-consultations-in-a-tertiary-care-centre-from-northern-india
#2
Abhilasha Williams, Anuradha Bhatia, Bimal Kanish, Paulina Rose Chaudhary, Clarence James Samuel
INTRODUCTION: The importance of dermatology inpatient consultation is of significant importance yet is not well documented. AIM: To retrospectively analyse the spectrum of dermatology inpatient consultations from the various departments and to document the most commonly occurring dermatological disorders from each speciality. MATERIALS AND METHODS: This study was done in an 800 bedded premier teaching hospital in Ludhiana, Punjab, North Western India...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208921/transurethral-cystolithotripsy-of-large-bladder-stones-by-holmium-laser-as-a-day-care-procedure
#3
Shantajit Nameirakpam, Salinita Naorem, M S Faridi, Kaku Singh Akoijam, Rajendra Singh Sinam
INTRODUCTION: Bladder stones constitute around 5% of bladder stones in the developed countries. Holmium laser lithotripsy has revolutionised the treatment of urinary lithiasis. AIM: The aim of this study was to report the outcome of transurethral cystolithotripsy with Holmium Laser under Local Anaesthesia (LA) as a day care procedure in patients with bladder stones. MATERIALS AND METHODS: Patients with bladder stone greater than 1.5cm attending urology Outpatient Department underwent transurethral cystolithotripsy with Holmium Laser under LA as day care procedure...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28197028/gross-morphological-study-of-the-renal-pelvicalyceal-patterns-in-human-cadaveric-kidneys
#4
T S R Anjana, Elangovan Muthian, Sivakami Thiagarajan, Sumathi Shanmugam
INTRODUCTION: The knowledge of detailed calyceal anatomy is essential for performing urologic procedures such as percutaneous nephrolithotomy, percutaneous nephrostomy, flexible ureterorenoscopy, endopyelotomy, and retrograde renal surgery. This study was performed to analyze the various patterns of pelvicalyceal system in the South Indian population, and compare these with previously published studies in different populations. METHODS: The study was conducted in 100 kidney specimens...
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28178112/antimicrobial-susceptibility-of-neisseria-gonorrhoeae-in-japan-from-2000-to-2015
#5
Mitsuru Yasuda, Kyoko Hatazaki, Shin Ito, Masataka Kitanohara, Mutsumasa Yoh, Munekado Kojima, Harunori Narita, Akira Kido, Kazutoyo Miyata, Takashi Deguch
BACKGROUND: Gonococcal infections are difficult to treat because of their multidrug antimicrobial resistance. The outbreak of antimicrobial-resistant Neisseria gonorrhoeae has begun in Asia and particularly in Japan. Therefore, it is very important that we understand the trend of antimicrobial resistance of N. gonorrhoeae in Asia including Japan. Our surveillance of the antimicrobial susceptibility of N. gonorrhoeae began in 2000 under the guidance of the Department of Urology, Gifu University...
March 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28168135/outcomes-of-bcg-induction-in-high-risk-non-muscle-invasive-bladder-cancer-patients-nmibc-a-retrospective-cohort-study
#6
Muhammad T Pirzada, Rashid Ghauri, Monis J Ahmed, Muhammad F Shah, Irfan Ul Islam Nasir, Jasim Siddiqui, Irfan Ahmed, Khurram Mir
Non-muscle-invasive bladder cancer (NMIBC) is categorized into high-risk and low-risk groups. Although, bacillus Calmette-Guerin (BCG) is the recommended adjuvant therapy of high-risk bladder tumor, optimal schedule (induction versus maintenance) of this therapy is a subject of debate. The objective was to evaluate outcomes of induction BCG in high-risk NMIBC patients at Shaukat Khanum Memorial Cancer Hospital & Research Centre, Pakistan and retrospective cohort study conducted in the department of urology, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Pakistan...
January 5, 2017: Curēus
https://www.readbyqxmd.com/read/28153591/the-present-and-future-challenges-facing-urology-departments-at-academic-health-centers
#7
REVIEW
Benjamin McCormick, Raj S Pruthi
Academic health centers have represented the pinnacle of healthcare, and continue to serve as examples around the world by providing innovative clinical care, cutting-edge research, and premier education. However, with recent changes in healthcare - particularly finances - the tripartite mission of the academic urology department is under fire. The next five to ten years are sure to bring immense change to AHCs in the United States as they adjust to new market and environmental conditions impacting the three distinct, but interrelated, elements of their mission...
January 30, 2017: Urology
https://www.readbyqxmd.com/read/28152018/acute-kidney-injury-burden-in-different-clinical-units-data-from-nationwide-survey-in-china
#8
Xiaojing Tang, Dongping Chen, Shengqiang Yu, Li Yang, Changlin Mei
BACKGROUND: The inpatient morbidity and mortality of acute kidney injury (AKI) vary considerably in different clinical units, yet studies to compare the difference remain limited. METHODS: We compared the clinical characteristics of AKI in Intensive Care Unit (ICU), medical and surgical departments by using the data derived from the 2013 nationwide cross-sectional survey of AKI in China to capture variations among different clinical departments in recognition, management, and outcomes of AKI...
2017: PloS One
https://www.readbyqxmd.com/read/28150382/making-models-to-simulate-testicular-swellings
#9
Piyush B Sarmah, Bhupendra D Sarmah, Husam Ibrahim, Jonathan Panting
BACKGROUND: Testicular examination and the recognition of common scrotal swellings is a key clinical skill that is difficult to teach undergraduates because of its intimate nature. A novel approach for this topic was prompted by the description of handmade models in the medical literature to teach anatomical knowledge and clinical skills. METHODS: Affordable low-cost materials were purchased and assembled to form six models replicating key scrotal pathologies: epididymal cyst, epididymitis, hydrocoele, inguinoscrotal hernia, testicular tumour and varicocoele...
February 2, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28149826/firearm-injury-in-a-child-an-uncommon-case-of-penile-trauma
#10
Mustafa Erman Dorterler, Mehmet Emin Boleken
Genitourinary system injuries generally occur due to blunt and penetrating trauma. Approximately 10% of all injuries encountered in the emergency department are related to the genitourinary system. Male genital trauma is a urological emergency because of the high risk of infection and the priority of protecting the sexual, endocrine, and reproductive functions. Blunt injuries to the penis are more often seen due to the mobility and localization of the penis than due to penetrating injuries caused by firearms or cutting instruments...
October 2016: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/28145398/assessment-of-bioelectrical-activity-of-pelvic-floor-muscles-depending-on-the-orientation-of-the-pelvis-in-menopausal-women-with-symptoms-of-stress-urinary-incontinence-continued-observational-study
#11
Kuba Ptaszkowski, Romuald Zdrojowy, Lucyna Slupska, Janusz Bartnicki, Janusz Dembowski, Tomasz Halski, Malgorzata Paprocka-Borowicz
BACKGROUND: Menopausal women often experience the prolapse of the uterus, bladder and rectum resulting from the failure and weakening of the pelvic floor muscles (PFM). Strengthening of the PFM through the standard exercises is recognized as an effective way of preventive measures and conservative treatment of the symptoms listed above, but still need to be improved. AIM: The goal was the objective assessment of resting and functional bioelectrical activity of pelvic floor muscle (PFM) in women during menopause and its comparison in three different positions of the pelvis: anterior pelvic tilt - position 1 (P1) posterior pelvic tilt - position 2 (P2) and neutral pelvic tilt - position 3 (P3)...
January 30, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28144694/-nationwide-survey-among-institutes-of-microbiology-in-academic-medicine-is-the-interdisciplinary-approach-the-right-way-to-treat-patients-with-urogenital-infections
#12
L Schneidewind, J Kranz, D Schlager, A E Pelzer
BACKGROUND: Increasing antibiotic resistance is a current and severe problem in medicine, especially in urology. Multidisciplinary antibiotic stewardship programmes are an important approach to counteract increasing resistance rates. This approach includes collaboration between urologists and microbiologists. OBJECTIVES: The primary endpoint was to describe the current setting of interdisciplinary work of urologists and microbiologists in university hospitals in Germany...
January 31, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28133337/-a-case-of-peritoneal-dissemination-of-hilar-cholangiocarcinoma-presenting-with-hematuria-six-years-after-radical-surgery
#13
Noriaki Koizumi, Yuen Nakase, Hiroki Kobayashi, Tsuyoshi Takagi, Kanehisa Fukumoto
A 76-year-old man underwent radical surgery for Stage IV a hilar cholangiocarcinoma in July 2009, and had been followed at an outpatient clinic. Although no apparent recurrent lesion was detected by PET/CT examination, an elevated CA19-9 level was found in January 2014. He was then started on the oral anticancer drug S-1. However, his CA19-9 level increased gradually. The patient presented to a urological department with a complaint of macrohematuria in May 2015. Detailed examination revealed a mass lesion at the top of the urinary bladder, which was suspected to be peritoneal dissemination of the known hilar cholangiocarcinoma invading the urinary bladder wall...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28128720/surgical-complications-after-pediatric-renal-transplant
#14
Hakan Sözen, Kibriya Fidan, Onur Özen, Oğuz Söylemezoğlu, Aydın Dalgıç
OBJECTIVES: Renal transplant is the most appropriate treatment for both adult and pediatric patients with end-stage renal failure. Here, we analyzed surgical complications after pediatric renal transplant at our center. MATERIALS AND METHODS: We retrospectively analyzed data from patient files and hospital charts of pediatric patients who had renal transplant at our center (Gazi University, Ankara, Turkey). Our immunosuppression protocol, a calcineurin inhibitor-based triple regimen, was applied to all recipients (steroids, mycophenolic acid)...
January 27, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28123517/role-of-free-testosterone-levels-in-patients-with-metastatic-castration-resistant-prostate-cancer-receiving-second-line-therapy
#15
Christoph A von Klot, Markus A Kuczyk, Alena Boeker, Christoph Reuter, Florian Imkamp, Thomas R W Herrmann, Hossein Tezval, Mario W Kramer, Sven Perner, Axel S Merseburger
A range of new treatment options has recently become available for patients with advanced metastatic castration-resistant prostate cancer (mCRPC). Androgen deprivation therapy (ADT) with luteinizing hormone-releasing hormone is continued when performing chemotherapy or androgen deprivation with new second-generation therapeutic agents such as enzalutamide or abiraterone acetate. Despite the fact that free testosterone (FT) is the biologically active form, it is common practice that androgen suppression is monitored via total testosterone levels only...
January 2017: Oncology Letters
https://www.readbyqxmd.com/read/28115836/relationship-between-lower-limb-position-and-pelvic-floor-muscle-surface-electromyography-activity-in-menopausal-women-a-prospective-observational-study
#16
Tomasz Halski, Kuba Ptaszkowski, Lucyna Słupska, Robert Dymarek, Małgorzata Paprocka-Borowicz
OBJECTIVES: In physiotherapeutic practice, special attention is being given to the reciprocal anatomical, physiological, and biomechanical relationship of the pelvis and the structures connected to it. However, the scientific literature shows mainly the theoretical information about their mutual connections. The lack of information about these relations from a practical aspect coupled with the paucity of scientific papers on the impact of posture changes on the pelvic floor led the authors to conduct this study...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28105866/feasibility-and-acceptability-of-couple-counselling-and-pelvic-floor-muscle-training-after-operation-for-prostate-cancer
#17
Randi V Karlsen, Pernille E Bidstrup, Helle Hvarness, Per Bagi, Elisabeth Friis Lippert, Rikke Permild, Annamaria Giraldi, Agnethe Lawaetz, Eva Krause, Ulla Due, Christoffer Johansen
BACKGROUND: Radical prostatectomy is often followed by long-lasting erectile dysfunction and urinary incontinence, with adverse effects on the quality of life and intimate relationship of patients and partners. We developed the ProCan intervention to ameliorate sexual and urological dysfunction after radical prostatectomy and examined its feasibility, acceptability and changes in sexual function. MATERIAL AND METHODS: Between May 2014 and October 2014, seven couples attending the Department of Urology, Rigshospitalet, were included 3-4 weeks after radical prostatectomy in the ProCan intervention, which consists of up to six couple counselling sessions, group instruction in pelvic floor muscle training (PFMT), up to three individual PFMT sessions and a DVD home training program...
January 20, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28099310/national-institutes-of-health-funding-to-departments-of-orthopaedic-surgery-at-u-s-medical-schools
#18
Jason Silvestre, Jaimo Ahn, L Scott Levin
BACKGROUND: The National Institutes of Health (NIH) is the largest supporter of biomedical research in the U.S., yet its contribution to orthopaedic research is poorly understood. In this study, we analyzed the portfolio of NIH funding to departments of orthopaedic surgery at U.S. medical schools. METHODS: The NIH RePORT (Research Portfolio Online Reporting Tools) database was queried for NIH grants awarded to departments of orthopaedic surgery in 2014. Funding totals were determined for award mechanisms and NIH institutes...
January 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28096928/spontaneous-uretero-sigmoid-fistula-secondary-to-calculus
#19
Ines Marzouk, Makram Moussa, Lotfi Saadallah, Sami Bouchoucha, Lotfi Hendaoui
A 25-year-old man was referred to the urology department after a subacute history of left back pain, burning micturition associated with pneumaturia and fecaluria. Ultrasonography was performed showing hydronephrosis, and plain film radiography demonstrated a long vertical left pelvic calculi. Uro-computed tomography (CT) combined with a water enema CT showed a 10 cm long calculus with the cranial extremity fistulating the sigmoidal wall. Surgical treatment included left nephroureterectomy and sigmoidectomy with a colorectal anastomosis...
November 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28090660/intermittent-catheterization-acceptance-test-i-cat-a-tool-to-evaluate-the-global-acceptance-to-practice-clean-intermittent-self-catheterization
#20
Amandine Guinet-Lacoste, Jacques Kerdraon, Alexandra Rousseau, Philippe Gallien, Jean-Gabriel Previnaire, Brigitte Perrouin-Verbe, Gérard Amarenco
AIM: In certain cases, a patient's anxiety, fear, or misconceptions can represent significant obstacles to the learning of Clean Intermittent Self Catheterization (CISC), and little is known about these psychological barriers. The aim of the present study is thus to construct and validate an "Intermittent Catheterization Acceptance Test (I-CAT)" to evaluate the psychological acceptance of CISC. METHODS: A study was carried out in nine neuro-rehabilitation and urology departments in French university hospitals...
January 16, 2017: Neurourology and Urodynamics
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