Eva Drevet Mulard, Sylvie Guibert, Anne Mey, Camille Lefevre, Marie-Agnès Chauvin, Claudie Pinteur, Marie-Ambre Monet, Murielle Godet, Anne-Marie Madec, Béatrice Morio, Jennifer Rieusset, Gilles J P Rautureau, Baptiste Panthu
Obesity is a risk factor for many diseases, such as type 2 diabetes and cardiovascular diseases. In line with the need for precision medicine, the search for biomarkers reporting the progression of obesity- and diet-associated disorders is urgent. We used NMR to determine the metabolomics profile of key organs (lung, liver, heart, skeletal muscle, kidney, and brain) and serum from male C57Bl/6J mice (5 weeks old) fed for 6, 10, and 14 weeks on a high-fat and high-sucrose diet (HFHSD) vs. a standard diet (STD)...
March 12, 2024: Nutrients