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https://www.readbyqxmd.com/read/28719842/spatiotemporal-gait-changes-with-use-of-an-arm-swing-cueing-device-in-people-with-parkinson-s-disease
#1
Elizabeth Thompson, Peter Agada, W Geoffrey Wright, Hendrik Reimann, John Jeka
Impaired arm swing is a common motor symptom of Parkinson's disease (PD), and correlates with other gait impairments and increased risk of falls. Studies suggest that arm swing is not merely a passive consequence of trunk rotation during walking, but an active component of gait. Thus, techniques to enhance arm swing may improve gait characteristics. There is currently no portable device to measure arm swing and deliver immediate cues for larger movement. Here we test report pilot testing of such a device, ArmSense (patented), using a crossover repeated-measures design...
July 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28719606/prescription-medicine-use-by-pedestrians-and-the-risk-of-injurious-road-traffic-crashes-a-case-crossover-study
#2
Mélanie Née, Marta Avalos, Audrey Luxcey, Benjamin Contrand, Louis-Rachid Salmi, Annie Fourrier-Réglat, Blandine Gadegbeku, Emmanuel Lagarde, Ludivine Orriols
BACKGROUND: While some medicinal drugs have been found to affect driving ability, no study has investigated whether a relationship exists between these medicines and crashes involving pedestrians. The aim of this study was to explore the association between the use of medicinal drugs and the risk of being involved in a road traffic crash as a pedestrian. METHODS AND FINDINGS: Data from 3 French nationwide databases were matched. We used the case-crossover design to control for time-invariant factors by using each case as its own control...
July 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28718987/the-impact-of-exercise-on-sleep-in-adults-with-type-1-diabetes
#3
Ravi Reddy, Joseph El Youssef, Kerri Winters-Stone, Deborah Branigan, Joseph Leitschuh, Jessica Castle, Peter G Jacobs
The aim of this pilot study was to investigate the impact of exercise on sleep and nocturnal hypoglycemia in adults with type 1 diabetes (T1D). In a 3-week crossover trial, 10 adults with T1D were randomized to perform aerobic, resistance or no exercise. During each exercise week, participants completed two separate 45-minute exercise sessions at an academic medical center. Participants returned home and wore a continuous glucose monitor and a wrist based activity monitor to estimate sleep duration. Participants on average lost 70 (±49) minutes of sleep (p = 0...
July 18, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28718171/younger-patients-and-men-achieve-higher-outcome-scores-than-older-patients-and-women-after-anterior-cruciate-ligament-reconstruction
#4
Kate E Webster, Julian A Feller
BACKGROUND: There is some evidence that functional performance and validated outcome scores differ according to the gender, age, and sport participation status of a patient after anterior cruciate ligament (ACL) reconstruction. However, the impact of these three factors, and interaction among them, has not been studied across a large relatively homogeneous group of patients to better elucidate their impact. QUESTIONS/PURPOSES: We reviewed a large cohort of patients who had undergone ACL reconstruction to determine if ROM, knee laxity, objective performance measures, and validated outcome scores differed according to (1) gender; (2) age; and (3) sport participation status...
July 17, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28716812/crossover-guard-meica1-prevents-meiotic-mishaps
#5
Jennifer Mach
No abstract text is available yet for this article.
July 17, 2017: Plant Cell
https://www.readbyqxmd.com/read/28716656/atomoxetine-in-abstinent-cocaine-users-cognitive-subjective-and-cardiovascular-effects
#6
Elise E DeVito, Aryeh I Herman, Noah S Konkus, Huiping Zhang, Mehmet Sofuoglu
No pharmacotherapies are approved for the treatment of cocaine use disorders (CUD). Behavioral treatments for CUD are efficacious for some individuals, but recovery rates from CUD remain low. Cognitive impairments in CUD have been linked with poorer clinical outcomes. Cognitive enhancing pharmacotherapies have been proposed as promising treatments for CUD. Atomoxetine, a norepinephrine transporter inhibitor, shows potential as a treatment for CUD based on its efficacy as a cognitive enhancer in other clinical populations and impact on addictive processes in preclinical and human laboratory studies...
July 14, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28716283/dalfampridine-in-parkinson-s-disease-related-gait-dysfunction-a-randomized-double-blind-trial
#7
Corneliu C Luca, Gloria Nadayil, Chuanhui Dong, Fatta B Nahab, Edelle Field-Fote, Carlos Singer
BACKGROUND: Disease-related gait dysfunction causes extensive disability for persons with Parkinson's disease (PD), with no effective therapies currently available. The potassium channel blocker dalfampridine has been used in multiple neurological conditions and improves walking in persons with multiple sclerosis. OBJECTIVES: We aimed to evaluate the effect of dalfampridine extended release (D-ER) 10mg tablets twice daily on different domains of walking in participants with PD...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28716083/influence-of-simethicone-and-fasting-on-the-quality-of-abdominal-ultrasonography-in-new-zealand-white-rabbits
#8
Kassy Gomes da Silva, Carla de Andrade, Cristina Santos Sotomaior
Presence of significant quantities of gas in the intestines may hinder a proper conduction of abdominal ultrasonography. In humans, preparatory techniques are used to solve this, but measures to avoid ultrasonographic complications due to intestinal gas in rabbits have not been reported. The objective of this study was to evaluate the influence of fasting and simethicone administered orally on the quality of ultrasonographic images of the gallbladder, kidneys, and jejunum in adult New Zealand White (NZW) rabbits...
July 17, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28716081/impact-of-a-nurse-led-telephone-intervention-on-satisfaction-and-health-outcomes-of-children-with-inflammatory-rheumatic-diseases-and-their-families-a-crossover-randomized-clinical-trial
#9
Anne-Sylvie Ramelet, Béatrice Fonjallaz, Laura Rio, Sandra Zoni, Pierluigi Ballabeni, Joachim Rapin, Christophe Gueniat, Michaël Hofer
BACKGROUND: Children suffering from rheumatic disease are faced with multidimensional challenges that affect their quality of life and family dynamics. Symptom management and monitoring of the course of the disease over time are important to minimize disability and pain. Poor disease control and anticipation of the need for treatment changes may be prompted by specialist medical follow-up and regular nurse-led consultations with the patient and families, in which information and support is provided...
July 17, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28715853/effect-of-gemfibrozil-or-rifampicin-on-the-pharmacokinetics-of-selexipag-and-its-active-metabolite-in-healthy-subjects
#10
Shirin Bruderer, Marc Petersen-Sylla, Margaux Boehler, Tatiana Remeňová, Atef Halabi, Jasper Dingemanse
AIMS: Based on in vitro data CYP2C8 is involved in the metabolism of selexipag and its active metabolite, ACT-333679. The present study evaluated the possible pharmacokinetic interactions of selexipag with gemfibrozil, a strong CYP2C8 inhibitor and rifampicin, an inducer of CYP2C8. METHODS: The study consisted of two independent parts, each conducted according to an open-label, randomized crossover design. The pharmacokinetics and safety of selexipag and ACT-333679 were studied following single-dose administration either alone or in the presence of multiple-dose gemfibrozil (Part I) or rifampicin (Part II) in healthy male subjects...
July 17, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28715304/influence-of-stretching-velocity-on-musculotendinous-stiffness-of-the-hamstrings-during-passive-straight-leg-raise-assessments
#11
Ty B Palmer, Nathaniel D M Jenkins, Brennan J Thompson, Joel T Cramer
BACKGROUND: Recently, passive musculotendinous stiffness (MTS) has been assessed manually in the field; however, when conducting these types of assessments, the stretching velocity must be controlled to avoid eliciting the stretch reflex, which can be observed by increased electromyographic (EMG) amplitude of the stretched muscles and greater resistive torque (indicating the assessment is no longer passive). OBJECTIVE: To examine the effects of slow, medium, and fast stretching velocities during manually-applied passive straight-leg raise (SLR) assessments on hamstrings MTS and EMG amplitude characteristics...
August 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28715283/temperate-water-immersion-as-a-treatment-for-hyperthermic-humans-wearing-american-football-uniforms
#12
Kevin C Miller, Tyler Truxton, Blaine Long
CONTEXT:   Cold-water immersion (CWI; 10°C) can effectively reduce body core temperature even if a hyperthermic human is wearing a full American football uniform (PADS) during treatment. Temperate-water immersion (TWI; 21°C) may be an effective alternative to CWI if resources for the latter (eg, ice) are unavailable. OBJECTIVE:   To measure rectal temperature (Trec) cooling rates, thermal sensation, and Environmental Symptoms Questionnaire (ESQ) scores of participants wearing PADS or shorts, undergarments, and socks (NOpads) before, during, and after TWI...
July 17, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28714983/tunable-room-temperature-magnetic-skyrmions-in-ir-fe-co-pt-multilayers
#13
Anjan Soumyanarayanan, M Raju, A L Gonzalez Oyarce, Anthony K C Tan, Mi-Young Im, A P Petrović, Pin Ho, K H Khoo, M Tran, C K Gan, F Ernult, C Panagopoulos
Magnetic skyrmions are nanoscale topological spin structures offering great promise for next-generation information storage technologies. The recent discovery of sub-100-nm room-temperature (RT) skyrmions in several multilayer films has triggered vigorous efforts to modulate their physical properties for their use in devices. Here we present a tunable RT skyrmion platform based on multilayer stacks of Ir/Fe/Co/Pt, which we study using X-ray microscopy, magnetic force microscopy and Hall transport techniques...
July 17, 2017: Nature Materials
https://www.readbyqxmd.com/read/28714858/hybridization-effects-on-wave-packet-dynamics-in-topological-insulator-thin-films
#14
Abdullah Yar, Muhammad Naeem, Safi Ullah Khan, Kashif Sabeeh
Theoretical study of electron wave packet dynamics in Topological Insulator (TI) thin films is presented. We have investigated real space trajectories and spin dynamics of electron wave packets in TI thin films. Our focus is on the role of hybridization between the electronic states of the two surfaces. This allows us to access the crossover regime of a thick film with no hybridization to a thin film with finite hybridization. We show that the electron wave packet undergoes side-jump motion in addition to zitterbewegung...
July 17, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28714749/the-influence-of-verbal-and-tactile-feedback-on-electromyographic-amplitude-of-the-shoulder-musculature-during-common-therapeutic-exercises
#15
Sean A Jones, Derek N Pamukoff, Timothy C Mauntel, J Troy Blackburn, Joseph B Myers
CONTEXT: Verbal and tactile feedback during rehabilitation exercises can improve muscle activation, thus improving the therapeutic benefits. However, it is unclear which feedback method elicits the greatest electromyographic (EMG) amplitude. OBJECTIVE: To determine if the addition of tactile to verbal feedback increases EMG amplitude of selected shoulder musculature during scapular plane elevation (Y's), shoulder horizontal abduction with external rotation (T's), and scapular retraction with external rotation (W's)...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28714534/adjustable-thermoplastic-oral-appliance-versus-positive-airway-pressure-for-obstructive-sleep-apnea
#16
Wish Banhiran, Paraya Assanasen, Cherdchai Nopmaneejumrudlers, Nongyoaw Nujchanart, Wimontip Srechareon, Cheerasook Chongkolwatana, Choakchai Metheetrairut
OBJECTIVES/HYPOTHESIS: To compare outcomes of continuous positive airway pressure (CPAP) and the adjustable thermoplastic mandibular advancement splint (AT-MAS) for obstructive sleep apnea treatment. STUDY DESIGN: Randomized crossover, noninferiority, tertiary center setting. METHODS: Fifty patients with a mean age of 49.5 ± 10.6 years were enrolled. Inclusion criteria were age ≥18 years, apnea-hypopnea index (AHI) ≥5 events/hour, and oxygen saturation ≥70%...
July 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28714466/quantifying-the-critical-thickness-of-electron-hybridization-in-spintronics-materials
#17
T Pincelli, V Lollobrigida, F Borgatti, A Regoutz, B Gobaut, C Schlueter, T-L Lee, D J Payne, M Oura, K Tamasaku, A Y Petrov, P Graziosi, F Miletto Granozio, M Cavallini, G Vinai, R Ciprian, C H Back, G Rossi, M Taguchi, H Daimon, G van der Laan, G Panaccione
In the rapidly growing field of spintronics, simultaneous control of electronic and magnetic properties is essential, and the perspective of building novel phases is directly linked to the control of tuning parameters, for example, thickness and doping. Looking at the relevant effects in interface-driven spintronics, the reduced symmetry at a surface and interface corresponds to a severe modification of the overlap of electron orbitals, that is, to a change of electron hybridization. Here we report a chemically and magnetically sensitive depth-dependent analysis of two paradigmatic systems, namely La1-xSrxMnO3 and (Ga,Mn)As...
July 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28714295/one-step-cationic-grafting-of-4-hydroxy-tempo-and-its-application-in-a-hybrid-redox-flow-battery-with-a-crosslinked-pbi-membrane
#18
Zhenjun Chang, Dirk Henkensmeier, Ruiyong Chen
By using a one-step epoxide ring-opening reaction between 4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (4-hydroxy-TEMPO) and glycidyltrimethylammonium cation (GTMA+), we synthesize a cation-grafted TEMPO (g+-TEMPO) and study its electrochemical performance against a Zn2+/Zn anode in a hybrid redox flow battery. To conduct Cl- counter anions, a crosslinked methylated polybenzimidazole (PBI) membrane was prepared and placed between the catholyte and anolyte. Compared to 4-hydroxy-TEMPO, the positively charged g+-TEMPO exhibits enhanced reaction kinetics...
July 17, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28713462/the-effect-of-foam-rolling-on-recovery-between-two-eight-hundred-metre-runs
#19
Anthony D'Amico, Vincent Paolone
With the increased popularity of foam rolling as a means of recovery, it is important to establish the exact manner in which the practice is useful. The purpose of this study was to examine the impact of foam rolling on recovery between two 800 m runs. Sixteen trained males (mean ± sd; age, 20.5 ± .5 yr; average 800 m treadmill run time, 145.2 ± 1.8 s) participated in the study, using a randomized, crossover design. The subjects completed two 800 m runs on a treadmill, separated by a 30 min rest, during which time a foam rolling protocol or passive rest period was performed...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28713256/baseline-performance-predicts-tdcs-mediated-improvements-in-language-symptoms-in-primary-progressive-aphasia
#20
Eric M McConathey, Nicole C White, Felix Gervits, Sherry Ash, H Branch Coslett, Murray Grossman, Roy H Hamilton
Primary Progressive Aphasia (PPA) is a neurodegenerative condition characterized by insidious irreversible loss of language abilities. Prior studies suggest that transcranial direct current stimulation (tDCS) directed toward language areas of the brain may help to ameliorate symptoms of PPA. In the present sham-controlled study, we examined whether tDCS could be used to enhance language abilities (e.g., picture naming) in individuals with PPA variants primarily characterized by difficulties with speech production (non-fluent and logopenic)...
2017: Frontiers in Human Neuroscience
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