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https://www.readbyqxmd.com/read/29729130/co2-retention-the-key-to-stopping-hiccups
#1
Toshiro Obuchi, Satoshi Shimamura, Naofumi Miyahara, Naoyuki Fujimura, Akinori Iwasaki
BACKGROUND: While investigating the mechanisms behind hiccups, our team discovered what could be the sufficient physiological conditions for terminating even persistent cases. METHODS: To investigate the role of CO2 retention, a healthy male volunteer was asked to perform 3 kinds of rebreathing experiments using different materials: (I) a 20L air-filled plastic bag, (II) a 20L air-filled plastic bag with a 1.5 × 1.5 cm hole, and (III) a 20L oxygen-filled plastic bag...
May 5, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29713552/persistent-hiccups-as-the-only-presenting-symptom-of-st-elevation-myocardial-infarction
#2
Nasreen Shaikh, Rishi Raj, Srinivas Movva, Charles Mattina
Clinical manifestations of acute myocardial infarction can be more than just chest pain. Patients can present with dyspnea, fatigue, heart burn, diaphoresis, syncope, and abdominal pain to name a few. Our patient was a 74-year-old male with a past medical history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and COPD due to chronic tobacco use, who presented with persistent hiccups for 4 days and no other complaints. Coincidently, he was found to have a diabetic foot ulcer with sepsis and acute kidney injury and hence was admitted to the hospital...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29701419/carotid-paraganglioma-classical-surgical-technique
#3
Bárbara Pereira, Manuel Fonseca, Anabela Gonçalves, João Alegrio, Óscar Gonçalves
INTRODUCTION: A carotid body tumor is a rare neoplasm, generally benign, that predominantly affects people between their fourth and fith decades of life. It manifests as a pulsatile and generally painless cervical mass with firm consistency, located below the angle of the jaw. Clinically it can cause localized pain, dysphagia, hiccups, hoarseness and hypersensitive carotid body syndrome. Surgery is the treatment of choice, bearing in mind the possibility of malignant transformation, peritumoral invasion and metastasis...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29668612/treatment-by-ultrasound-guided-local-infiltration-in-adhesion-related-abdominal-pain-and-intractable-hiccups-a-case-report
#4
Dan Zhu, Zhi-Yong Gu, Chia-Shiang Lin, Fa-Chuan Nie, Jian Cui
RATIONALE: Abdominal pain and hiccups secondary to intra-abdominal adhesion are surgical complications that are often treated by painkillers and secondary surgeries with an unsatisfactory therapeutic effect. This study presents a new treatment method that uses ultrasound-guided local infiltration in peritoneal and abdominal wall adhesions in patients with hiccups and abdominal pain. PATIENT CONCERNS: A 62-year-old patient presented to our hospital with a history of intractable hiccups and abdominal pain for 30 years...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29615600/persistent-hiccups-after-cervical-epidural-steroid-injection
#5
Ahmad Khaled Abubaker, Daher K Rabadi, Manal Kassab, Mohannad A Al-Qudah
BACKGROUND Hiccup is a rare complication after a cervical epidural steroid injection used in the treatment of chronic pain. A few studies have reported on the physiological and pharmacological aspects of hiccups after epidural steroid injection and there have been some case reports published. Our presented case report provides insight into the side effect of hiccups that can occur in association with cervical epidural analgesia, and will help inform anesthesiologist about this unpleasant complication. CASE REPORT We present a rare case of persistent hiccups after a cervical epidural steroid injection in a 60-year-old male patient with chronic pain due to disc protrusion in C3-C7...
April 4, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29534401/-characteristics-of-neuromyelitis-optica-spectrum-disorder-associated-with-the-area-postrema
#6
X F You, H T Hu, J Ye
Objective: To evaluate the clinical characteristics and the corresponding MRI and laboratory findings in patients with neuromyelitis optica spectrum disorder (NMOSD) associated with area postrema (AP). Methods: The study was a retrospective analysis of data from 120 NMOSD patients, and 18 cases were with AP out of these patients, The clinical presentation, MRI changes, serological markers and treatment outcome were reported. Results: AP occurred in 18 patients (15%, 18/120). AP was the onset symptom in 14 (14/18) patients and 3 days to 7 months (median 40 days) later, optic neuritis or myelitis was involved...
March 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29502375/-therapeutic-effect-of-cervical-jiaji-electroacupuncture-on-postoperative-intractable-hiccup-of-liver-neoplasms
#7
RANDOMIZED CONTROLLED TRIAL
S K Zhang, W B Gao, Y Liu, H He
Objective: To evaluate the therapeutic effect of cervical Jiaji electroacupuncture on postoperative intractable hiccup of liver neoplasms. Methods: A total of 39 patients with postoperative intractable hiccup of liver neoplasms in The First Affiliated Hospital of Heilongjiang University of Chinese Medicine from May 2013 to May 2017 were collected and divided into 2 groups randomly. The electroacupuncture group included 20 cases, the control group included 19 cases. Patients in the electroacupuncture group were treated by cervical Jiaji electroacupuncture (located in C3-5, sympathetic ganglion), while the control group were treated by metoclopramide combined with chlorpromazine for three days...
February 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29419660/continuous-cervical-epidural-block-treatment-for-intractable-hiccups
#8
Jung Eun Kim, Mi Kyoung Lee, Dong Kyu Lee, Sang Sik Choi, Jong Sun Park
Intractable hiccups, although rare, may result in severe morbidity, including sleep deprivation, poor food intake, respiratory muscle fatigue, aspiration pneumonia, and death. Despite these potentially fatal complications, the etiology of intractable hiccups and definitive treatment are unknown. This study aimed to evaluate the effectiveness of continuous cervical epidural block in the treatment of intractable hiccups.Records from 28 patients with a history of unsuccessful medical and invasive treatments for hiccups were evaluated...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29382620/brain-abscess-of-basal-ganglia-presenting-with-persistent-hiccups
#9
Jared Sweeney, Alexa Bodman, Walter A Hall
BACKGROUND: Brain abscesses are well-known to neurologic surgeons with well-recognized presentations, which include seizures, neurologic deficit, and headache. Rare symptoms may lead to a delay in diagnosis, which can be life threatening in the setting of a brain abscess. CASE DESCRIPTION: We present the case of a 46-year-old male with intractable hiccups found to have an abscess of the right basal ganglia. The brain abscess was treated by frameless stereotactic-guided aspiration...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29368226/lateral-medullary-infarction-with-cardiovascular-autonomic-dysfunction-an-unusual-presentation-with-review-of-the-literature
#10
REVIEW
Tridu R Huynh, Barbara Decker, Timothy J Fries, Ajay Tunguturi
PURPOSE: We report an unusual case of lateral medullary infarction presenting with orthostatic hypotension with pre-syncope without vertigo or Horner's syndrome. METHODS: Case report with review of the literature. RESULTS: A 67-year-old man presented with pre-syncope and ataxia without vertigo. Initial brain CT and MRI were normal. Neurological evaluation revealed right-beating nystagmus with left gaze, vertical binocular diplopia, right upper-extremity dysmetria, truncal ataxia with right axial lateropulsion, and right-facial and lower extremity hypoesthesia...
January 24, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29348287/recurrent-hiccups-may-signal-brainstem-pathology-and-should-be-investigated
#11
Dmitri Shastin, Priya Nidamanuri, Ravindra Nannapaneni
While occasional hiccups are normal, their persistent recurrence is distressing and may have an underlying aetiology. Patients with recurrent hiccups may undergo a long journey and see many physicians before the diagnosis is finally made. The purpose of this report is to increase awareness of central nervous system lesions as a possible cause for recurrent hiccups and provide an illustrative case of an otherwise fit man presenting with ongoing hiccups caused by a medullary haemangioblastoma.
January 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29324501/nonpharmacologic-management-of-acute-singultus-hiccups
#12
Daniel S Orlovich, Jay B Brodsky, John G Brock-Utne
No abstract text is available yet for this article.
March 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29305117/conus-medullaris-arteriovenous-malformation-presenting-with-acute-dysphagia-and-intractable-hiccups
#13
Josephine Jung, Ahilan Kailaya-Vasan, Christopher Kellett, Fadi Almahariq, Gordan Grahovac
BACKGROUND: Conus medullaris arteriovenous malformations (AVMs) are rare spinal vascular malformations presenting most frequently with features of myelopathy (Foix-Alajounine syndrome), radiculopathy, bowel/bladder dysfunction, or acute spinal hemorrhage (Coup de poignard of Michon) causing profound neurological deficit. Here we present the case of a young patient with progressive dysphagia and intractable hiccups as a rare first presentation symptom of later verified conus medullaris AVM...
March 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29302825/tramadol-induced-hiccups-a-report-of-two-cases
#14
Radhika Panchal, Vishal Bhutt, Ashish Anovadiya, Bhargav Purohit, Firdaus Dekhaiya, Nutanbala Goswami
Hiccups can be idiopathic, psychogenic and organic, with drugs being one of the most important causes of hiccups. Although the exact pathophysiological processes involved are still poorly understood, the neurotransmitters dopamine, serotonin, and γ-aminobutyric acid (GABA) have been documented to play a significant role in the generation of hiccups. We report on two patients with cellulitis who developed hiccups with the use of tramadol as an analgesic. The possible mechanisms and clinical implications of this rare adverse event are discussed...
January 5, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29288849/intractable-hiccups-after-coil-embolization-of-partially-thrombosed-posterior-inferior-cerebellar-artery-aneurysm
#15
Mitsuru Hashiguchi, Atsushi Fujita, Mitsuru Ikeda, Masashi Morikawa, Eiji Kohmura
BACKGROUND: Hiccups are defined as sudden-onset involuntary contractions of the diaphragm followed by immediate inspiration and laryngeal closure, and they are considered intractable if prolonged beyond 1 month. A reflux arc involving phrenic, vagal, and central midbrain modulation is likely responsible for hiccups. We herein report a case of intractable hiccups caused by compression of the dorsal aspect of the medulla oblongata after treatment of a partially thrombosed distal posterior inferior cerebellar artery (PICA) aneurysm...
March 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29231488/-clinical-data-analysis-of-279-inpatients-with-acupuncture-consultation-in-a-comprehensive-hospital
#16
Yamin Zhang, Hua Sun, Suhui Chen, Hong Xu, Fei Bao
OBJECTIVE: To analyze the current status of acupuncture consultation in Peking Union Medical College Hospital, which could provide references and suggestions for the development of acupuncture at comprehensive hospitals and the treatment of diseases. METHODS: The source of departments, the number of patients, the number of consultation, treatment frequency, consultation reasons and western medicine diagnosis of 279 inpatients who received acupuncture consultation were analyzed...
February 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29210718/successful-treatment-of-idiopathic-intractable-hiccup-with-cisatracurium-under-intravenous-general-anesthesia-a-case-report
#17
Jian-Ping Wu, Jian-Xiong An, Xiao-Yan Qian, Yong Wang
We report the successful treatment of idiopathic intractable hiccups with cisatracurium under intravenous general anesthesia. The patient had a history of hiccups for 19 years that were refractory to a variety of treatments. When his hiccups were accompanied by vomiting, insomnia, shortness of breath, and poor oral intake for 9 days, he sought relief. We administered a nondepolarizing muscle relaxant, cisatracurium, during total intravenous anesthesia, to stop the hiccups. The duration of the anesthetic was determined by the time it took for the patient to recover from the neuromuscular blockade without reversal the cisatracurium...
November 27, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29147855/phase-ii-study-of-palonosetron-aprepitant-and-dexamethasone-to-prevent-nausea-and-vomiting-induced-by-multiple-day-emetogenic-chemotherapy
#18
Takeshi Ioroi, Junya Furukawa, Manabu Kume, Sachi Hirata, Yuko Utsubo, Naomi Mizuta, Hideaki Miyake, Masato Fujisawa, Midori Hirai
PURPOSE: This study aimed to determine the antiemetic efficacy and safety of palonosetron, aprepitant and dexamethasone in patients with testicular germ cell tumours (TGCTs) receiving 5-day cisplatin-based combination chemotherapy. METHODS: In this open-label, single-arm, single-centre study, the antiemetic therapy consisted of palonosetron 0.75 mg on day 1, aprepitant 125 mg on day 1 and 80 mg on days 2-7 and dexamethasone 6.6 mg on days 1-7. The primary endpoint was complete response (CR; no vomiting/retching or rescue medication) in the overall period (0-240 h), and secondary endpoints included complete protection (CP; defined as CR and no more than mild nausea) and total control (TC; defined as CR and no nausea)...
November 16, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29125442/long-term-outcomes-after-surgical-treatment-of-pediatric-neurogenic-thoracic-outlet-syndrome
#19
Jennifer Hong, Jared M Pisapia, Zarina S Ali, Austin J Heuer, Erin Alexander, Gregory G Heuer, Eric L Zager
OBJECTIVE Neurogenic thoracic outlet syndrome (nTOS) is an uncommon compression syndrome of the brachial plexus that presents with pain, sensory changes, and motor weakness in the affected limb. The authors reviewed the clinical presentations and outcomes in their series of pediatric patients with surgically treated nTOS over a 6-year period. METHODS Cases of nTOS in patients age 18 years or younger were extracted for analysis from a prospective database of peripheral nerve operations. Baseline patient characteristics, imaging and neurophysiological data, operative findings, and outcomes and complications were assessed...
January 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29079070/pharmacologic-interventions-for-intractable-and-persistent-hiccups-a-systematic-review
#20
Nick B Polito, Shawn E Fellows
BACKGROUND: Chlorpromazine is the only drug approved by the US Food and Drug Administration for the treatment of hiccups; however, many other pharmacologic treatments have been proposed for intractable and persistent hiccups. Currently, there is little evidence to support the use of one agent over another. OBJECTIVE: This review aims to identify literature concerning the use of pharmacologic treatments for intractable and persistent hiccups with the goal of evaluating therapies in terms of their level of evidence, mechanism of action, efficacy, dosing, onset of action, and adverse effects...
October 2017: Journal of Emergency Medicine
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