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https://www.readbyqxmd.com/read/28330689/evaluation-of-methohexital-as-an-alternative-to-propofol-in-a-high-volume-outpatient-pediatric-sedation-service
#1
Nicholas E Jones, Michael S Kelleman, Harold K Simon, Jana A Stockwell, Courtney McCracken, Michael D Mallory, Pradip P Kamat
BACKGROUND: Propofol is a preferred agent for many pediatric sedation providers because of its rapid onset and short duration of action. It allows for quick turn around times and enhanced throughput. Occasionally, intravenous (IV) methohexital (MHX), an ultra-short acting barbiturate is utilized instead of propofol. OBJECTIVE: Describe the experience with MHX in a primarily propofol driven outpatient sedation program and to see if it serves as an acceptable alternative when propofol is not the preferred pharmacologic option...
March 8, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28281110/headache-in-neuromyelitis-optica
#2
REVIEW
Alina Masters-Israilov, Matthew S Robbins
PURPOSE OF REVIEW: Neuromyelitis optica (NMO) classically features a clinical presentation that includes longitudinally extensive transverse myelitis and optic neuritis. However, many other pathognomonic phenomena have more recently been described in patients diagnosed with NMO, including intractable hiccups, vomiting, and painful tonic spasms, but less has been reported regarding the relationship between NMO and headache. Though headache is well established as both a symptom and comorbidity of multiple sclerosis (MS), it has been much less described thus far in the NMO literature and warrants more careful evaluation...
April 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28243153/intractable-hiccups-caused-by-esophageal-diverticular-candidiasis-in-an-immunocompetent-adult-a-case-report
#3
Shinsuke Yahata, Tsuneaki Kenzaka, Saeko Kushida, Hogara Nishisaki, Hozuka Akita
INTRODUCTION: Various causes of intractable hiccups have been reported; however, to the best of our knowledge, there are no previous reports of either intractable hiccups due to esophageal candidiasis in an immunocompetent adult or improvement following antifungal therapy. CASE PRESENTATION: An 87-year-old man presented with intractable hiccups. Although the patient was immunocompetent, he used proton pump inhibitors. An esophagogastroduodenos-copy revealed several white deposits throughout the esophagus and extensive white deposits in the midesophageal diverticulum...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28203564/neurotoxicity-following-the-ingestion-of-bilimbi-fruit-averrhoa-bilimbi-in-an-end-stage-renal-disease-patient-on-hemodialysis
#4
Camille Pereira Caetano, Cinara Barros de Sá, Bruno Antônio Paixão Faleiros, Marcelo Fonseca Coutinho Fernandes Gomes, Edna Regina Silva Pereira
INTRODUCTION: The toxic effects of the ingestion of star fruit (Averrhoa carambola) in chronic kidney disease patients are well described in the literature. Recently, the compound caramboxin has been isolated, explaining the mechanisms of its neurotoxicity. Bilimbi fruit belongs to the family Oxalidaceae, Averrhoa bilimbi species, and exhibits similar biochemical characteristics to star fruit. OBJECTIVE: To report the case of a patient with chronic kidney disease who developed a seizure disorder after the ingestion of bilimbi fruit...
January 2017: Case Reports in Nephrology and Dialysis
https://www.readbyqxmd.com/read/28202826/-hypogeusia-and-high-signals-in-the-nuclei-of-the-solitary-tract-on-mri-due-to-varicella-zoster-virus-infection-a-case-report
#5
Yuji Shiga, Yuhei Kanaya, Shinichi Takeshima, Yutaka Shimoe, Akio Tanaka, Masaru Kuriyama
A 63-year-old man noticed hypogeusia after presenting hiccups for several days. He was serologically diagnosed with varicella-zoster virus (VZV) infection, but had no skin lesions typical of herpes (zoster sine herpete). Hypogeusia was confirmed by electrogustometry and the filter-paper disk method, which showed damage in the areas innervated by the cord of tympanum, glossopharyngeal nerve, and greater petrosal nerve. High signals in the nuclei of the solitary tract of the medulla oblongata and the enhancement of the bilateral intracranial segments of the cranial nerve IX and X complex were observed by magnetic resonance imaging (MRI)...
February 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28196104/analysis-of-factors-associated-with-hiccups-based-on-the-japanese-adverse-drug-event-report-database
#6
Ryuichiro Hosoya, Yoshihiro Uesawa, Reiko Ishii-Nozawa, Hajime Kagaya
Hiccups are occasionally experienced by most individuals. Although hiccups are not life-threatening, they may lead to a decline in quality of life. Previous studies showed that hiccups may occur as an adverse effect of certain medicines during chemotherapy. Furthermore, a male dominance in hiccups has been reported. However, due to the limited number of studies conducted on this phenomenon, debate still surrounds the few factors influencing hiccups. The present study aimed to investigate the influence of medicines and patient characteristics on hiccups using a large-sized adverse drug event report database and, specifically, the Japanese Adverse Drug Event Report (JADER) database...
2017: PloS One
https://www.readbyqxmd.com/read/28174382/-persistent-chemotherapy-induced-hiccups-successfully-treated-with-pregabalin
#7
REVIEW
Kyoko Nakanishi, Kumi Sugiyama, Yasushi Abe, Tetsushi Endo, Yoshinobu Ohsaki
A 62-year-old male was diagnosed with large cell lung cancer(c-Stage IV)based on pathological examination of an anterior chest tumor. He received chemotherapy with cisplatin, pemetrexed, and bevacizumab. He suffered from persistent hiccups from day 2 of the first course of chemotherapy. He was unsuccessfully treated with chlorpromazine, shakuyakukanzoto, and gabapentin. Therefore, we administered pregabalin to him, and his hiccups subsided immediately. To prevent hiccups, he subsequently took pregabalin along with his chemotherapy regimen, and was able to receive 4 courses of chemotherapy without persistent hiccups...
January 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28151955/predicting-ebola-severity-a-clinical-prioritization-score-for-ebola-virus-disease
#8
Mary-Anne Hartley, Alyssa Young, Anh-Minh Tran, Harry Henry Okoni-Williams, Mohamed Suma, Brooke Mancuso, Ahmed Al-Dikhari, Mohamed Faouzi
BACKGROUND: Despite the notoriety of Ebola virus disease (EVD) as one of the world's most deadly infections, EVD has a wide range of outcomes, where asymptomatic infection may be almost as common as fatality. With increasingly sensitive EVD diagnosis, there is a need for more accurate prognostic tools that objectively stratify clinical severity to better allocate limited resources and identify those most in need of intensive treatment. METHODS/PRINCIPAL FINDINGS: This retrospective cohort study analyses the clinical characteristics of 158 EVD(+) patients at the GOAL-Mathaska Ebola Treatment Centre, Sierra Leone...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28149102/magnetic-resonance-imaging-brain-findings-in-a-case-of-aquaporin-4-antibody-positive-neuromyelitis-optica-spectrum-disorder-presenting-with-intractable-vomiting-and-hiccups
#9
Prerna Garg, Muthusubramanian Rajasekaran, Salil Pandey, Gnanashanmugam Gurusamy, Devanand Balalakshmoji, Rajakumar Rathinasamy
Neuromyelitisoptica (NMO) and multiple sclerosis (MS) were once considered to be differing manifestation of same auto immune disease, NMO predominantly involving the optic nerve and cord. Now with discovery of NMO antibody the concept has changed and a spectrum of disorders with lesions in brain has been identified. Occasionally, brain may be the first or the only site of involvement in these disorders hence it is essential to be aware of this spectrum. The brain lesions in NMO/NMOSD may be located in characteristic regions and present with symptoms mimicking non neurological disease...
January 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28103503/sedative-hypnotic-like-effect-and-molecular-docking-of-di-naphthodiospyrol-from-diospyros-lotus-in-an-animal-model
#10
Abdur Rauf, Taibi Ben Hadda, Ghias Uddin, José P Cerón-Carrasco, Jorge Peña-García, Horacio Pérez-Sánchez, Haroon Khan, Saud Bawazeer, Seema Patel, Mohammad S Mubarak, Tareq Abu-Izneid, Yahia Nasser Mabkhot
BACKGROUND: Diospyros lotus Linn commonly known as date-plum, or Caucasian persimmon has multiple uses in folk medicine. Various parts of this plant is used for alleviating lumbago, dysponea, hemorrhage, insomnia, and hiccup. The plant extracts possess a variety of biological activities, such as anti-inflammatory, sedative, febrifuge, anti-microbial, vermifuge, and anti-hypertensive. AIM/HYPOTHESIS: The aim of the present work is to investigate the sedative-hypnotic effect of a rare dimeric napthoquione 1 obtained from the chloroform soluble fraction of D...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28090161/2017-presages-dramatic-change-for-federal-health-care-policies-republicans-are-likely-to-face-hiccups-along-the-way
#11
Stephen Barlas
President-elect Donald Trump campaigned on a promise to repeal Obamacare. We review what effect the incoming administration may have on U.S. health care policy.
January 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28041755/a-case-of-singultus-avoiding-a-hiccup-in-care
#12
Jeffrey Gardecki, James Espinosa, Alan Lucerna, Jarrid Bernhardt
Hiccups (singultus) is often a benign, common and self- limited condition. A case of profound electrolyte disturbances presenting with chief complaint of hiccups is presented in which chlorpromazine was not administered and could have been problematic had it been given. For those who present to the ED with chief complaint of hiccups, it is critical to consider a life threatening etiology as the cause of their symptom. This case presents a potential pitfall in the management of singultus.
December 23, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28025072/enhancing-biopharmaceutical-attributes-of-phospholipid-complex-loaded-nanostructured-lipidic-carriers-of-mangiferin-systematic-development-characterization-and-evaluation
#13
Rajneet Kaur Khurana, Arvind K Bansal, Sarwar Beg, Andrea Julie Burrow, O P Katare, Kamalinder K Singh, Bhupinder Singh
Mangiferin (Mgf), largely expressed out from the leaves and stem bark of Mango, is a potent antioxidant. However, its in vivo activity gets tremendously reduced owing to poor aqueous solubility and inconsistent gastrointestinal absorption, high hepatic first-pass metabolism and high P-gp efflux. The current research work, therefore, was undertaken to overcome the biopharmaceutical hiccups by developing the Mgf-phospholipid complex (PLCs) loaded in nanostructured lipidic carriers (NLCs). The PLCs and NLCs were prepared using refluxing, solvent evaporation and hot emulsification technique, respectively with three molar ratios of Mgf and Phospholipon 90G, i...
December 23, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27919188/clinical-analysis-of-neuromyelitis-optica-presenting-as-intractable-nausea-vomiting-and-hiccups
#14
Xuehong Jin, Shaofang Pei, Yi Liu, Xia Li
Vomiting and hiccups can be the manifestations of numerous systemic and neurological illnesses. Intractable nausea, vomiting and hiccups (INH) are reported as possible initial manifestations of neuromyelitis optica (NMO), but not correctly identified. Awareness of these atypical presentations is conducive to NMO early diagnosis and proper treatment to prevent further disability. In this paper, 12 NMO were reported, whose intractable vomiting and hiccups were the sole manifestations of the first attack and other attacks involving spinal cord and optic nerves developed later...
December 16, 2016: International Journal of Neuroscience
https://www.readbyqxmd.com/read/27888403/the-predictor-of-mortality-outcome-in-adult-patients-with-ebola-virus-disease-during-the-2014-2015-outbreak-in-guinea
#15
M S Cherif, N Koonrungsesomboon, M P Diallo, E Le Gall, D Kassé, F Cherif, A Koné, M Diakité, F Camara, N Magassouba
The purpose of this study was to examine the association of any demographic and clinical factors with mortality outcome among adult patients with Ebola virus disease (EVD) in Guinea. This retrospective observational study analyzed medical records of laboratory confirmed EVD adult patients during the 2014-2015 EVD outbreak in Guinea. The associations between any demographic or clinical variables and mortality outcome of EVD were assessed using univariate and multivariate logistic regression analyses. Of 2,310 EVD adult patients included for analysis, the overall case fatality rate was 68...
April 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27867581/the-diseases-of-airway-tracheal-diverticulum-a-review-of-the-literature
#16
REVIEW
Asli Tanrivermis Sayit, Muzaffer Elmali, Dilek Saglam, Cetin Celenk
Tracheal diverticulum (DV) is a type of paratracheal air cyst (PTAC) that is often asymptomatic and usually detected incidentally by imaging methods. Tracheal DV are divided into two subgroups: congenital and acquired. Dysphagia, odynophagia, neck pain, hoarseness, hemoptysis, choking, and recurrent episodes of hiccups and burping can also be seen in symptomatic patients. Thin-section multidetector computed tomography (MDCT) is useful for diagnosis of tracheal diverticulum. The relationship between DV and tracheal lumen can be demonstrated by axial, coronal, and sagittal reformat multiplanar images...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27849511/hiatal-hernia-as-the-cause-of-g-induced-abdominal-pain
#17
Scott B Hughey, Lauren H Mattingly
Sliding hiatal hernias are common and affect approximately 10% to 80% of the general population. The condition typically presents with reflux-type symptoms and is diagnosed either with imaging or endoscopy. In this case, the hernia presented as G-induced abdominal pain. The patient was an F-18 pilot who experienced worsening epigastric abdominal pain proportionate to the amount of accelerative force experienced. The pain would occur at approximately 3 Gs and increase beyond that. The patient was asymptomatic at rest and denied any dysphagia or reflux symptoms...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27832331/role-of-nasogastric-tube-in-children-undergoing-elective-distal-bowel-surgery
#18
Niyaz Ahmed Khan, Subhasis Roy Choudhury, Partap Singh Yadav, Raghu Prakash, Jigar N Patel
BACKGROUND: Nasogastric tubes are being routinely used in children and adults undergoing elective abdominal surgery without much scientific evidence supporting their true usefulness. The aim of our study was to assess the role of nasogastric tube in children undergoing elective distal bowel surgery. MATERIALS AND METHODS: All pediatric patients undergoing elective distal bowel surgery were enrolled and randomized into two groups: those with nasogastric tube (NG group) or without nasogastric tube (NNG group)...
November 10, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27816172/an-infrequent-cause-of-persistent-hiccup
#19
A L Esparza-Quezada, S Bielsa, J M Porcel
No abstract text is available yet for this article.
November 2, 2016: Revista Clínica Española
https://www.readbyqxmd.com/read/27815938/visualization-and-quantitation-of-fetal-movements-by-real-time-three-dimensional-ultrasound-with-live-xplane-imaging-in-the-first-trimester-of-pregnancy
#20
Ye Lu, Taizhu Yang, Hong Luo, Feng Deng, Qianyun Cai, Weiwei Sun, Hao Song
AIM: To prove whether real-time three-dimensional (3D) ultrasound with live xPlane imaging is better in observing fetal movements than standard ultrasound imaging. METHODS: 50 healthy women with singleton pregnancies (22-43 years old) at 11 to 14 weeks of gestation underwent real-time 3D ultrasound examination with live xPlane imaging from July 2014 to February 2015. The incidence and frequency of 10 fetal movement patterns in 10 minutes were evaluated, including general movements (GMs), isolated arm movements, isolated leg movements, hiccup, stretching, breathing, startle, jaw opening, isolated head retroflexion, and isolated head anteflexion...
October 31, 2016: Croatian Medical Journal
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