Juan Pablo Cuello, Ariana Meldaña Rivera, Enric Monreal, Ana Gómez Lozano, Ana Maria García Cano, Jose Manuel García Domínguez, José Ignacio Fernández Velasco, Lucienne Costa-Frossard França, Haydee Goicochea, Yolanda Higueras, Juan Antonio De León-Luis, Susana Sainz De La Maza, Noelia Villarrubia, Ignacio Arribas Gómez, Irene Ruiz Perez, Maria Luisa Martinez Ginés, Luisa María Villar
BACKGROUND: Patient disability, relapse rate, and age are used for family planning in multiple sclerosis (MS). However, the need for more accurate biomarkers is widely recognized. We aimed to explore the influence of age on neurofilament light chain (sNfL), which reflects acute inflammation; glial fibrillary acidic protein (GFAP), associated with disability progression independent of relapses; and anti-Müllerian hormone (AMH), reflecting ovarian reserve, to provide a tailored family planning strategy...
2024: Frontiers in Neurology