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Peng Jiang, Yang Feng, Feng Wu
This study addresses the optimization of node redeployment coverage in underwater wireless sensor networks. Given that nodes could easily become invalid under a poor environment and the large scale of underwater wireless sensor networks, an underwater sensor network redeployment algorithm was developed based on wolf search. This study is to apply the wolf search algorithm combined with crowded degree control in the deployment of underwater wireless sensor networks. The proposed algorithm uses nodes to ensure coverage of the events, and it avoids the prematurity of the nodes...
October 21, 2016: Sensors
Bing Guo, Yongqiang Zhang, Shili Li, Ting Lai, Liang Yang, Juanni Chen, Wei Ding
Many cereals accumulate hydroxamic acids involved in defense of plant against various fungi, bacteria, and insects. 2,4-dihydroxy-7-methoxy-1,4-benzoxazine-3-one, commonly known as DIMBOA, is one of the principal cyclic hydroxamic acids in aqueous extracts of maize. The aim of this study was to evaluate the antibacterial activity of the isolated DIMBOA and its derivatives 2-benzoxazolinone (BOA), 6-chloro-2-benzoxazolinone (CDHB), and 2-mercaptobenzothiazole (MBT) against Ralstonia solanacearum. MBT showed the strongest antibacterial activity, followed by CDHB and DIMBOA, with minimum inhibitory concentrations (MICs) of 50, 100 and 200 mg/L, respectively, better than the BOA with 300 mg/L...
October 19, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Jiaxiang Huang, Maoguo Gong, Lijia Ma
Molecular interactions data increase exponentially with the advance of biotechnology. This makes it possible and necessary to comparatively analyse the different data at a network level. Global network alignment is an important network comparison approach to identify conserved subnetworks and get insight into evolutionary relationship across species. Network alignment which is analogous to subgraph isomorphism is known to be an NP-hard problem. In this paper, we introduce a novel heuristic Particle-Swarm-Optimization based Network Aligner (PSONA), which optimizes a weighted global alignment model considering both protein sequence similarity and interaction conservations...
October 19, 2016: IEEE/ACM Transactions on Computational Biology and Bioinformatics
Stephen J Simpson
No abstract text is available yet for this article.
February 2016: Pathology
Oihane Irazoki, Jesús Aranda, Timo Zimmermann, Susana Campoy, Jordi Barbé
In addition to its role in DNA damage repair and recombination, the RecA protein, through its interaction with CheW, is involved in swarming motility, a form of flagella-dependent movement across surfaces. In order to better understand how SOS response modulates swarming, in this work the location of RecA and CheW proteins within the swarming cells has been studied by using super-resolution microscopy. Further, and after in silico docking studies, the specific RecA and CheW regions associated with the RecA-CheW interaction have also been confirmed by site-directed mutagenesis and immunoprecipitation techniques...
2016: Frontiers in Microbiology
Tobias Marczewski, Yong-Peng Ma, Xue-Mei Zhang, Wei-Bang Sun, A Jane Marczewski
Hybridisation has become a focal topic in evolutionary biology, and many taxonomists are aware that the process occurs more frequently than previously assumed. Nonetheless many species and varieties are still described without explicitly considering the possibility of hybridisation, especially in countries that have relatively short scientific histories, but which often possess the highest species diversities. Furthermore, new taxa are often described based only on herbarium specimens, not taking into account information from wild populations, significantly decreasing the potential to detect morphologies arising from hybridisation at this crucial descriptive stage...
October 6, 2016: AoB Plants
Hanan R Shehata, Cassandra L Ettinger, Jonathan A Eisen, Manish N Raizada
Endophytes are microbes that inhabit internal plant tissues without causing disease. Some endophytes are known to combat pathogens. The corn (maize) landrace Chapalote has been grown continuously by subsistence farmers in the Americas since 1000 BC, without the use of fungicides, and the crop remains highly valued by farmers, in part for its natural tolerance to pests. We hypothesized that the pathogen tolerance of Chapalote may, in part, be due to assistance from its endophytes. We previously identified a bacterial endophyte from Chapalote seeds, Burkholderia gladioli strain 3A12, for its ability to combat a diversity of crop pathogens, including Sclerotinia homoeocarpa, the most important fungal disease of creeping bentgrass, a relative of maize used here as a model system...
2016: Frontiers in Microbiology
Xinpei Ma, Chun-An Chou, Hiroki Sayama, Wanpracha Art Chaovalitwongse
Many neuroscience studies have been devoted to understand brain neural responses correlating to cognition using functional magnetic resonance imaging (fMRI). In contrast to univariate analysis to identify response patterns, it is shown that multi-voxel pattern analysis (MVPA) of fMRI data becomes a relatively effective approach using machine learning techniques in the recent literature. MVPA can be considered as a multi-objective pattern classification problem with the aim to optimize response patterns, in which informative voxels interacting with each other are selected, achieving high classification accuracy associated with cognitive stimulus conditions...
September 2016: Brain Informatics
Ying Liang, Zisheng Guo, Lang Gao, Qianqian Guo, Liyue Wang, Yan Han, Kangmin Duan, Lixin Shen
Pseudomonas aeruginosa (PAO1) is an important opportunistic pathogen that thrives in various environments. It is known that the structural variations of the lipopolysaccharide (LPS), including lipid A moiety play an important role in encountering environmental changes. Genes PA3242 and PA0011 have recently been reported to be responsible for secondary-acylation of lipid A in P. aeruginosa. In this study, we confirmed that the PA3242-dependant secondary acylation affects the growth, antibiotic resistance and virulence of PAO1 and functions as a more predominant acyltransferase than PA0011...
October 13, 2016: Microbial Pathogenesis
Richa Barsainya, Tarun Kumar Rawat, Manjeet Kumar
In this paper, a novel design of fractional order differentiator (FOD) based on lattice wave digital filter (LWDF) is proposed which requires minimum number of multiplier for its structural realization. Firstly, the FOD design problem is formulated as an optimization problem using the transfer function of lattice wave digital filter. Then, three optimization algorithms, namely, genetic algorithm (GA), particle swarm optimization (PSO) and cuckoo search algorithm (CSA) are applied to determine the optimal LWDF coefficients...
October 12, 2016: ISA Transactions
Jason Hindes, Klementyna Szwaykowska, Ira B Schwartz
Swarming behavior continues to be a subject of immense interest because of its centrality in many naturally occurring systems in physics and biology, as well as its importance in applications such as robotics. Here we examine the effects on swarm pattern formation from delayed communication and topological heterogeneity, and in particular, the inclusion of a relatively small number of highly connected nodes, or "motherships," in a swarm's communication network. We find generalized forms of basic patterns for networks with general degree distributions, and a variety of dynamic behaviors including parameter regions with multistability and hybrid motions in bimodal networks...
September 2016: Physical Review. E
A Soumana, M Kamaye, M Mamane, D Mamoudou, A Samailla, A Moussa, H Dima, T Guéro
We report a fatal case due to a massive attack by a swarm of bees in a nine-year-old child. The accident was fatal because of two aggravating factors: the cephalic location and the large number of stings (about 300). Complications were coagulopathy, anemia, hemorrhage, coma, and oligoanuria. Support was symptomatic at a facility second level. The outcome was fatal within 14 days. In view of the encountered difficulties, we recommend to build written protocols for the management of envenomation in any health training reference...
October 13, 2016: Bulletin de la Société de Pathologie Exotique
Christos C Ioannou
Larger groups often have a greater ability to solve cognitive tasks compared to smaller ones or lone individuals. This is well established in social insects, navigating flocks of birds, and in groups of prey collectively vigilant for predators. Research in social insects has convincingly shown that improved cognitive performance can arise from self-organised local interactions between individuals that integrates their contributions, often referred to as swarm intelligence. This emergent collective intelligence has gained in popularity and been directly applied to groups of other animals, including fish...
October 11, 2016: Behavioural Processes
Yuta Tsuji, Prasad L V K Dasari, S F Elatresh, Roald Hoffmann, N W Ashcroft
In pursuit of new lithium-rich phases and potential electrides within the Li-N phase diagram, we explore theoretically the ground-state structures and electronic properties of Li4N at P = 1 atm. Crystal structure exploration methods based on particle swarm optimization and evolutionary algorithms led to 25 distinct structures, including 23 dynamically stable structures, all quite close to each other in energy, but not in detailed structure. Several additional phases were obtained by following the imaginary phonon modes found in low-energy structures, as well as structures constructed to simulate segregation into Li and Li3N...
October 12, 2016: Journal of the American Chemical Society
Abhijit Sarkar, Marta Marszalkowska, Martin Schäfer, Tobias Pees, Hannah Klingenberg, Franziska Macht, Barbara Reinhold-Hurek
The endophyte Azoarcus sp. BH72, fixing nitrogen microaerobically, encounters low O2 -tensions in flooded roots. Therefore, its transcriptome upon shift to microaerobiosis was analyzed using oligonucleotide microarrays. 8.7% of the protein-coding genes were significantly modulated. Aerobic conditions induced expression of genes involved in oxidative stress protection, while under microaerobiosis 233 genes were up-regulated, encoding hypothetical proteins, transcriptional regulators, and proteins involved in energy metabolism, among them a cbb3 -type terminal oxidase contributing to but not essential for N2 -fixation...
October 11, 2016: Environmental Microbiology
Brandon S Coventry, Aravindakshan Parthasarathy, Alexandra L Sommer, Edward L Bartlett
Particle swarm optimization (PSO) has gained widespread use as a general mathematical programming paradigm and seen use in a wide variety of optimization and machine learning problems. In this work, we introduce a new variant on the PSO social network and apply this method to the inverse problem of input parameter selection from recorded auditory neuron tuning curves. The topology of a PSO social network is a major contributor to optimization success. Here we propose a new social network which draws influence from winner-take-all coding found in visual cortical neurons...
October 10, 2016: Journal of Computational Neuroscience
Ramanathan Srinivasan, Kannan Rama Devi, Arunachalam Kannappan, Shunmugiah Karutha Pandian, Arumugam Veera Ravi
ETHNOPHARMACOLOGICAL RELEVANCE: Piper betle, a tropical creeper plant belongs to the family Piperaceae. The leaves of this plant have been well known for their therapeutic, religious and ceremonial value in South and Southeast Asia. It has also been reported to possess several biological activities including antimicrobial, antioxidant, antinociceptive, antidiabetic, insecticidal and gastroprotective activities and used as a common ingredient in indigenous medicines. In Indian system of ayurvedic medicine, P...
October 6, 2016: Journal of Ethnopharmacology
Jinyan Li, Simon Fong, Shirley Siu, Sabah Mohammed, Jinan Fiaidhi, Kelvin K L Wong
Drug design involves classification of protein binding which is usually done in a computer simulation prior to extensive actual tests. Accurate classification of protein binding is essential but it is obstructed with a very challenging task of feature selection (FS) because there are too many potential features. Dorothea as a case of virtual screening in drug design, has 100,000 features that inflate to a very huge (of size 2(100,000) possible candidate feature subsets to be selected) but very sparse search space...
September 30, 2016: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
L Xu, L Li, P Yang, Z Ma
The migratory locust (Locusta migratoria) shows aggregative traits in nymph marching bands and swarm formations through mutual olfactory attraction of conspecifics. However, olfactory preference in different nymph stages in gregarious locusts is not sufficiently explored. In this study, we found that the nymph olfactory preference for gregarious volatiles exhibited obvious variations at different developmental stages. The gregarious locusts show attractive response to conspecific volatiles from the third stadium...
October 7, 2016: Insect Molecular Biology
Daria R Bulanova, Yevhen A Akimov, Anne Rokka, Teemu D Laajala, Tero Aittokallio, Petri Kouvonen, Teijo Pellinen, Sergey G Kuznetsov
G-Protein Coupled Receptor (GPCR), Class C, Group 5, Member A (GPRC5A) has been implicated in several malignancies. The underlying mechanisms, however, remain poorly understood. Using a panel of human cell lines, we demonstrate that CRISPR/Cas9-mediated knockout and RNAi-mediated depletion of GPRC5A impairs cell adhesion to integrin substrates: collagens I and IV, fibronectin, as well as to extracellular matrix proteins derived from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma (Matrigel). Consistent with the phenotype, knock-out of GPRC5A correlated with a reduced integrin β1 (ITGB1) protein expression, impaired phosphorylation of the focal adhesion kinase (FAK), and lower activity of small GTPases RhoA and Rac1...
October 7, 2016: Cell Adhesion & Migration
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