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JOURNAL ARTICLE
Ingridi Camboim Franceschi, Rubem Augusto da Paixão Dornas, Isabel Salgueiro Lermen, Artur Vicente Pfeifer Coelho, Ademir Henrique Vilas Boas, Adriano Garcia Chiarello, Adriano Pereira Paglia, Agnis Cristiane de Souza, Alana Rafaela Borsekowsky, Alessandro Rocha, Alex Bager, Alexander Zaidan de Souza, Alexandre Martins Costa Lopes, Aloysio Souza de Moura, Aluane Silva Ferreira, Alvaro García-Olaechea, Ana Cláudia Delciellos, Ana Elisa de Faria Bacellar, Ana Kellen Nogueira Campelo, Ana Maria Oliveira Paschoal, Anderson Claudino Rolim, André Luiz Ferreira da Silva, Andre Monnerat Lanna, André Pereira da Silva, Andresa Guimarães, Ângela Cardoso, Angelica Soligo Cassol, Anna Ludmilla da Costa-Pinto, Ariel Guilherme Santos do Nascimento, Arthur Soares Fernandes, Aryanne Clyvia, Aureo Banhos Dos Santos, Barbara Lima-Silva, Beatriz de Mello Beisiegel, Beatriz Fernandes Lima Luciano, Bernardo de Faria Leopoldo, Bruna Nunes Krobel, Bruno Busnello Kubiak, Bruno Henrique Saranholi, Bruno Senna Correa, Caio Sant Anna Teixeira, Camila Rezende Ayroza, Camila Righetto Cassano, Camilo Benitez-Riveros, Carla Cristina Gestich, Carla Denise Tedesco, Carla Gheler-Costa, Carla Grasiele Zanin Hegel, Carlito da Silva Evangelista Junior, Carlos Eduardo Morando Faria Ferreira, Carlos Eduardo Viveiros Grelle, Carolina Franco Esteves, Caroline da Costa Espinosa, Caroline Leuchtenberger, Catalina Sanchéz-Lalinde, Cauanne Iglesias Campos Machado, Cecilia Andreazzi, Cecília Bueno, Cecilia Cronemberger de Faria, Claudio Novaes, Cynthia Elisa Widmer, Cyntia Cavalcante Santos, Daniel da Silva Ferraz, Daniel Galiano, Daniela Aparecida Savariz Bôlla, Daniela Behs, Daniele Pereira Rodrigues, Danielle Picão de Melo, Déborah Maria Soares Ramos, Denise Lidório de Mattia, Diego Dias Pavei, Diogo Loretto, Douglas da Silva Huning, Douglas de Matos Dias, Éder Ricardo Paetzhold, Elaine Rios, Eleonore Zulnara Freire Setz, Eliana Cazetta, Emanuel Giovani Cafofo Silva, Emanuelle Pasa, Erica Naomi Saito, Erick Francisco Silva de Aguiar, Érika Paula Castro, Ernesto Bastos Viveiros de Castro, Ezequiel Pedó, Fabiane de Aguiar Pereira, Fábio Bolzan, Fábio de Oliveira Roque, Fábio Dias Mazim, Fábio Henrique Comin, Fábio Maffei, Felipe Bortolotto Peters, Felipe Moreli Fantacini, Felipe Pessoa da Silva, Felipe Santana Machado, Felipe Vélez-Garcia, Fernanda Stussi Duarte Lage, Fernando Araújo Perini, Fernando Camargo Passos, Fernando Carvalho, Fernando Cesar Cascelli de Azevedo, Fernando Ferreira, Fernando Ferreira de Pinho, Flávia Guimarães Chaves, Flavia Regina Miranda, Flavio Henrique Guimarães Rodrigues, Flávio Kulaif Ubaid, Francisco Homem Gabriel, Franco Leandro de Souza, Fred Victor de Oliveira, Gabriel Cupolillo, Gabriela de Araújo Pires Moreira, Gabriela Mette, Gabriela Teixeira Duarte, Gabrielle Beca, Gilberto Corso, Gilmar Perbiche-Neves, Glauber Henrique Borges de Oliveira Souto, Glenda Jéssica da Silva Vilarroel, Graziele O Batista, Guilherme Braga Ferreira, Gustavo Alves da Costa Toledo, Gustavo Senger, Helena de Godoy Bergallo, Hellen Cristina Pinheiro Dos Santos, Humberto Angelo Gazola, Isabel Melo, Ismael Verrastro Brack, Iuri Veríssimo, Ivan Réus Viana, Izabela Costa Laurentino, Jaime Luis Diehl, Jairo José Zocche, Jimi Martins-Silva, João Paulo Gava Just, Jorge José Cherem, Jorge Luiz Nascimento, Jorge Reppold Marinho, José Oliveira Dantas, Jose Roberto de Matos, José Salatiel Rodrigues Pires, Josi Fernanda Cerveira, Juan Ruiz-Esparza, Juliana Paulo da Silva, Juliano André Bogoni, Karina Theodoro Molina, Karla Dayane de Lima Pereira, Karoline Ceron, Kristel de Vleeschouwer, Laís Lautenschlager, Larissa Bailey, Larissa Fornitano, Lilian Elaine Rampim, Lorena Sforza, Luan Gonçalves Bissa, Luca Mattos Santucci, Lucas Gonçalves da Silva, Lucas Neves Perillo, Lucas Ribeiro Correa, Ludmila Hufnagel, Luis Fernando Alberti, Luis Jose Recalde Mello, Luis Renato Rezende Bernardo, Luiz Gustavo Rodrigues Oliveira-Santos, Luiza Neves Guimarães, Maíra Benchimol, Manuela Catharina Twardowschy, Marcela Ferreira-Riveros, Marcelo da Silva, Márcia Maria de Assis Jardim, Marco Aurélio Leite Fontes, Marcos Adriano Tortato, Marcos Tadeu do Nascimento, Margareth Lumy Sekiama, Maria Clara Nascimento-Costa, Maria Ester Bueno Dos Santos, Maria Santina de Castro Morini, Mariana Baldy Nagy-Reis, Mariane da Cruz Kaizer, Mariano José Ribeiro da Silva Sant'Anna, Marilia Teresinha Hartmann, Marina Ochoa Favarini, Marina Oliveira Olivo, Martín Alejandro Montes, Martin Roberto Del Valle Alvaréz, Matheus Feldstein Haddad, Maurício Djalles Costa, Maurício Eduardo Graipel, Mauricio Quoos Konzen, Mauro Galetti, Meyline de Oliveira Souza Almeida, Michel Barros Faria, Micheli Ribeiro Luiz, Michelle Noronha da Matta Baptista, Miguel Ângelo Marini, Milton Cezar Ribeiro, Natalie Olifiers, Natasha Moraes de Albuquerque, Nicolás Cantero, Nivaldo Peroni, Noeli Zanella, Olívia Mendonça-Furtado, Olivier Pays, Orlando Ednei Ferretti, Oscar Rocha-Barbosa, Paloma Marques Santos, Patrícia Menegaz de Farias, Patrício Adriano da Rocha, Paul François Colas-Rosas, Paula Ribeiro-Souza, Paula Ferracioli, Paulo Afonso Hartmann, Paulo de Tarso Zuquim Antas, Paulo Ribeiro, Paulo Tomasi Sarti, Paulo Ivo Mônico, Pedro Volkmer de Castilho, Peônia Brito de Moraes Pereira, Peter Gransden Crawshaw, Pierre-Cyril Renaud, Rafael Spilere Romagna, Rafael Turíbio Moraes de Sousa, Raíssa Soares Spagnol, Raone Beltrão-Mendes, Ravi Fernandes Mariano, Renata Reinoso Rocha, Renata Sousa-Lima, Renata Valls Pagotto, Rhayssa Terra de Faria, Ricardo Corassa Arrais, Ricardo Moratelli, Ricardo Sartorello, Rita de Cassia Bianchi, Roberto de Carvalho Guimarães, Rodrigo Lima Massara, Romulo Theodoro Costa, Rosane Vera Marques, Ruan Márcio Ruas Nunes, Sandra Maria Hartz, Saulo Meneses Silvestre de Sousa, Saulo Ramos Lima, Sergio Lutz Barbosa, Silvia Neri Godoy, Stephen Francis Ferrari, Talita Guimarães de Araújo-Piovezan, Talita Laura Góes, Tatiane Campos Trigo, Thales R O de Freitas, Thiago Bernardes Maccarini, Thiago Marcial de Castro, Thiago Ribas Bella, Tonny Marques de Oliveira Junior, Uslaine Maciel Cunha, Vanessa Tavares Kanaan, Vera Pfannerstill, Victor Siqueira Pimentel, Vilmar Picinatto Filho, Vinícius Nunes Alves, Viviana Rojas-Bonzi, Viviane Mottin, Vlamir José Rocha, Andreas Kindel, Igor Pfeifer Coelho
Camera traps became the main observational method of a myriad of species over large areas. Data sets from camera traps can be used to describe the patterns and monitor the occupancy, abundance, and richness of wildlife, essential information for conservation in times of rapid climate and land-cover changes. Habitat loss and poaching are responsible for historical population losses of mammals in the Atlantic Forest biodiversity hotspot, especially for medium to large-sized species. Here we present a data set from camera trap surveys of medium to large-sized native mammals (>1 kg) across the Atlantic Forest...
April 12, 2024: Ecology
#2
REVIEW
Leandro Luongo Matos, Luiz Paulo Kowalski, Aline Lauda Freitas Chaves, Thiago Bueno de Oliveira, Gustavo Nader Marta, Maria Paula Curado, Gilberto de Castro Junior, Terence P Farias, Gustavo Sarria Bardales, Mario Avila Cabrera, Renato de Castro Capuzzo, Genival Barbosa de Carvalho, Claudio Roberto Cernea, Rogério Aparecido Dedivitis, Fernando Luiz Dias, Andrés Munyo Estefan, Agustin Horacio Falco, Gustavo Alberto Ferraris, Alejandro Gonzalez-Motta, Andre Guimarães Gouveia, Alexandre Arthur Jacinto, Marco Aurelio Vamondes Kulcsar, Ana Kober Leite, Renan Bezerra Lira, Milena Perez Mak, Pedro De Marchi, Evandro Sobroza de Mello, Fátima Cristina Mendes de Matos, Pablo H Montero, Eduardo Dias de Moraes, Fabio Ynoe de Moraes, Diego Chaves Rezende Morais, Fernando Miguel Poenitz, Adela Poitevin, Hernán Ortiz Riveros, Álvaro Sanabria, Miguel Ticona-Castro, José Guilherme Vartanian, Gustavo Viani, Eugenio F Vines, William Nassib William Junior, David Conway, Shama Virani, Paul Brennan
Head and neck squamous cell carcinoma (HNSCC) is well known as a serious health problem worldwide, especially in low-income countries or those with limited resources, such as most countries in Latin America. International guidelines cannot always be applied to a population from a large region with specific conditions. This study established a Latin American guideline for care of patients with head and neck cancer and presented evidence of HNSCC management considering availability and oncologic benefit. A panel composed of 41 head and neck cancer experts systematically worked according to a modified Delphi process on (1) document compilation of evidence-based answers to different questions contextualized by resource availability and oncologic benefit regarding Latin America (region of limited resources and/or without access to all necessary health care system infrastructure), (2) revision of the answers and the classification of levels of evidence and degrees of recommendations of all recommendations, (3) validation of the consensus through two rounds of online surveys, and (4) manuscript composition...
April 2024: JCO global oncology
#3
JOURNAL ARTICLE
Matheus Fernandes Alves, Albert Katchborian-Neto, Paula Carolina Pires Bueno, Fausto Carnevale-Neto, Rosana Casoti, Miller Santos Ferreira, Michael Murgu, Ana Claudia Chagas de Paula, Danielle Ferreira Dias, Marisi Gomes Soares, Daniela Aparecida Chagas-Paula
We introduce a liquid chromatography - mass spectrometry with data-independent acquisition (LC-MS/DIA)-based strategy, specifically tailored to achieve comprehensive and reliable glycosylated flavonoid profiling. This approach facilitates in-depth and simultaneous exploration of all detected precursors and fragments during data processing, employing the widely-used open-source MZmine 3 software. It was applied to a dataset of six Ocotea plant species. This framework suggested 49 flavonoids potentially newly described for these plant species, alongside 45 known features within the genus...
March 26, 2024: RSC Advances
#4
JOURNAL ARTICLE
Mariane Dias Duarte de Carvalho Souza, Larissa Bueno Ferreira, Luana Caroline Dos Santos
In pregnant women, the Energy-adjusted Dietary Inflammatory Index (E-DII) is adopted to measure the inflammatory potential of the diet, but it does not predict the quality of the diet. Our hypothesis is that a more pro-inflammatory diet during pregnancy is also a poorer quality diet. Thus, the objective of this study is to verify the association of the E-DII with the Diet Quality Index Adapted for Pregnancy (DQI-P) and the nutrient intake from the diet in terms of the second and third gestational trimesters...
February 13, 2024: Nutrition Research
#5
JOURNAL ARTICLE
Brunna Garcia de Souza Leite, Carlos Alexandre Granghelli, Fabricia de Arruda Roque, Rachel Santos Bueno Carvalho, Mário Henrique Scapin Lopes, Paulo Henrique Pelissari, Mylena Tuckmantel Dias, Cristiane Soares da Silva Araújo, Lúcio Francelino Araújo
Two trials were performed in order to evaluate the effects of dietary Kraft lignin inclusion on broiler performance, ileal nutrient digestibility, blood lipid profile, intestinal morphometry, and lipid oxidation of meat. Trial 1 was conducted in order to evaluate performance and ileal digestibility for the period of 1 to 21 d of age, randomly distributing 490 day-old broiler chicks across 5 dietary treatments with 14 replicates containing 7 birds each in metabolic cages, while trial 2 was executed in order to evaluate performance, blood parameters, intestinal morphometry, carcass yield and abdominal fat, and lipid oxidation for the period of 1 to 42 d of age, randomly distributing 900 day-old broiler chicks across 5 dietary treatments with 15 replicates of 12 birds each in floor pens, being each bird in trial 2 challenged with coccidiosis vaccine at 10 d of age...
February 1, 2024: Poultry Science
#6
JOURNAL ARTICLE
Albert Katchborian-Neto, Matheus F Alves, Paula C P Bueno, Karen de Jesus Nicácio, Miller S Ferreira, Tiago B Oliveira, Henrique Barbosa, Michael Murgu, Ana C C de Paula Ladvocat, Danielle F Dias, Marisi G Soares, João H G Lago, Daniela A Chagas-Paula
Liquid chromatography coupled with high-resolution mass spectrometry data-independent acquisition (LC-HRMS/DIA), including MSE, enable comprehensive metabolomics analyses though they pose challenges for data processing with automatic annotation and molecular networking (MN) implementation. This motivated the present proposal, in which we introduce DIA-IntOpenStream, a new integrated workflow combining open-source software to streamline MSE data handling. It provides 'in-house' custom database construction, allows the conversion of raw MSE data to a universal format (...
January 22, 2024: Briefings in Bioinformatics
#7
JOURNAL ARTICLE
Angélica Bueno Barbezan, Wilmmer Alexander Arcos Rosero, Daniel Perez Vieira, Maria Eduarda Zaganin Rigo, Giovana Dias da Silva, Alex Alves Rodrigues, Luís Fernando de Almeida, Fábio Fernando Alves da Silva, Andy González Rivera, Natanael Gomes da Silva, Emerson S Bernardes, Carlos Alberto Zeituni, Maria Elisa C M Rostelato
Background: Nanotechnology has revolutionized medicine, especially in oncological treatments. Gold nanoparticles (AuNPs) stand out as an innovative alternative due to their biocompatibility, potential for surface modification, and effectiveness in radiotherapeutic techniques. Given that prostate cancer ranks as one of the leading malignancies among men, there's a pressing need to investigate new therapeutic approaches. Methods: AuNPs coated with bovine serum albumin (BSA) were synthesized and their cytotoxicity was assessed against prostate tumor cell lines (LNCaP and PC-3), healthy prostate cells (RWPE-1), and endothelial control cells (HUVEC) using the MTS/PMS assay...
2024: Nanotheranostics
#8
JOURNAL ARTICLE
Sandra Viviana García, María Celeste Velazquez, Alberto Emiliano D Agostino, Diego Julián Salto, Fernanda Melina Lardies Arenas, Sílvia Veronica Cuozzo, Ladislao Pablo Matias Diaz Ballve, Tatiana Dias de Carvalho
INTRODUCTION: Within the context of the COVID-19 pandemic, children were confined to their homes. The Buenos Aires Metropolitan Area (AMBA) region has the highest urban density in Argentina and has been the epicenter of COVID-19 infections and deaths. The objectives of this study are to characterize the habits of screen use, sedentary lifestyle and physical activity and describe their associations, in children under six years of age from AMBA, Argentina. METHODS: analytical and cross-sectional study, in which data from the online survey (Google Forms®) were used...
December 26, 2023: Revista de la Facultad de Ciencias Médicas
#9
JOURNAL ARTICLE
Andreza Aparecida Ribeiro, Jorge Alexandre Nogueira Santos, Paula Pio de Oliveira Salem, Mario Ferreira Conceição Santos, Paula Carolina Pires Bueno, João Henrique Ghilardi Lago, Danielle Ferreira Dias, Daniela Aparecida Chagas de Paula, Marisi Gomes Soares
Jungia floribunda Less. is a shrub belonging to the Asteraceae. The infusion of its leaves has been used, in folk medicine of several South American countries, as anti-inflammatory and hypoglycaemic agent. In the present study, the infusion of leaves from J. floribunda was obtained and its chemical composition was determined by UHPLC-MS associated with molecular network allowing the annotation of flavonoids, sesquiterpene lactones, coumarins, and chlorogenic acid derivatives. Besides, in vitro elastase activity assay was carried out with the infusion...
December 13, 2023: Natural Product Research
#10
JOURNAL ARTICLE
Tatiane Cristina Silva Maiolini, Karen de Jesus Nicácio, Welton Rosa, Daniel de Oliveira Miranda, Mario Ferreira Conceição Santos, Paula Carolina Pires Bueno, João Henrique Ghilardi Lago, Patricia Sartorelli, Danielle Ferreira Dias, Daniela Aparecida Chagas de Paula, Marisi Gomes Soares
Many species from Myrtaceae have traditionally been used in traditional medicine as anti-inflammatory, antimicrobial, antidiarrheal, antioxidant and antirheumatic, besides in blood cholesterol reduction. In the present work, the anti-inflammatory activity of essential oils from eighteen Myrtaceae spp. were evaluated according to their ex-vivo anti-inflammatory activity in human blood, and the corresponding biomarkers were determined using untargeted metabolomics data and multivariate data analysis. From these studied species, six displayed anti-inflammatory activity with percentage rates of inhibition of PGE2 release above 70%...
November 24, 2023: Natural Product Research
#11
JOURNAL ARTICLE
Ennya Rafaella Neves Cardoso, Stephani Félix Carvalho, Sarah Alves Dias, Rayane Almeida Santos, Mariana Avelar Tavares, Lucianne Cardoso Neves, Warley Vieira de Freitas Paula, Gracielle Teles Pádua, Nicolas Jalowitzki de Lima, Raquel Loren Dos Reis Paludo, Isabela Santos Silva, Raphaela Bueno Mendes Bittencourt, Gabriel Cândido Dos Santos, Flavia Giovana de Jesus Nascimento, Luiza Gabriella Ferreira de Paula, Filipe Dantas-Torres, Caio Marcio De Oliveira Monteiro, Felipe da Silva Krawczak
Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii , the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of two A. sculptum populations from Goiás state (midwestern Brazil) to different acaricides. The first tick population (GYN strain) originated from an experimental farm, where the ticks are annually exposed to acaricides. The second (PNE strain) was collected in a national park (Emas National Park), where the ticks had not been exposed to acaricides...
October 31, 2023: Pathogens
#12
JOURNAL ARTICLE
Álisson Coldebella da Silva, Juliete Nathali Scholl, Amanda de Fraga Dias, Augusto Ferreira Weber, Fernanda Bueno Morrone, Olga Cruz-López, Ana Conejo-García, Joaquín María Campos, Jean Sévigny, Fabrício Figueiró, Ana Maria Oliveira Battastini
Bladder cancer (BC) is the most common cancer of the urinary tract. Bozepinib (BZP), a purine-derived molecule, is a potential compound for the treatment of cancer. Purinergic signaling consists of the activity of nucleosides and nucleotides present in the extracellular environment, modulating a variety of biological actions. In cancer, this signaling is mainly controlled by the enzymatic cascade involving the NTPDase/E-NPP family and ecto-5'-nucleotidase/CD73, which hydrolyze extracellular adenosine triphosphate (ATP) to adenosine (ADO)...
October 31, 2023: Purinergic Signalling
#13
JOURNAL ARTICLE
Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma.
David Kotol, Jakob Woessmann, Andreas Hober, María Bueno Álvez, Khue Hua Tran Minh, Fredrik Pontén, Linn Fagerberg, Mathias Uhlén, Fredrik Edfors
Mass spectrometry based on data-independent acquisition (DIA) has developed into a powerful quantitative tool with a variety of implications, including precision medicine. Combined with stable isotope recombinant protein standards, this strategy provides confident protein identification and precise quantification on an absolute scale. Here, we describe a comprehensive targeted proteomics approach to profile a pan-cancer cohort consisting of 1800 blood plasma samples representing 15 different cancer types. We successfully performed an absolute quantification of 253 proteins in multiplex...
September 28, 2023: Cancers
#14
JOURNAL ARTICLE
Jenny Ruiz
No abstract text is available yet for this article.
October 10, 2023: Journal of Clinical Oncology
#15
JOURNAL ARTICLE
Ana Margarida Gonçalves Carvalho Dias, Inês Pimentel Moreira, Iana Lychko, Cátia Lopes Soares, Arianna Nurrito, Arménio Jorge Moura Barbosa, Viviane Lutz-Bueno, Raffaele Mezzenga, Ana Luísa Carvalho, Ana Sofia Pina, Ana Cecília Afonso Roque
Reflectins are a family of intrinsically disordered proteins involved in cephalopod camouflage, making them an interesting source for bioinspired optical materials. Understanding reflectin assembly into higher-order structures by standard biophysical methods enables the rational design of new materials, but it is difficult due to their low solubility. To address this challenge, we aim to understand the molecular self-assembly mechanism of reflectin's basic unit-the protopeptide sequence YMDMSGYQ-as a means to understand reflectin's assembly phenomena...
2023: Frontiers in Chemistry
#16
JOURNAL ARTICLE
Natalia Mulinari Turin de Oliveira, Vanessa S Schneider, Laryssa Regis Bueno, Lara Luisa Valerio de Mello Braga, Karien Sauruk da Silva, Liziane Cristine Malaquias da Silva, Maria Luiza Souza, Bruna Barbosa da Luz, Cleiane Dias Lima, Ruan Sousa Bastos, Maria Fernanda de Paula Werner, Elizabeth Soares Fernandes, Jefferson Almeida Rocha, Marcelo Biondaro Gois, Lucimara Mach Côrtes Cordeiro, Daniele Maria-Ferreira
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) of the gastrointestinal tract. The etiology is not fully understood, but environmental, microbial, and immunologic factors, as well as a genetic predisposition, play a role. UC is characterized by episodes of abdominal pain, diarrhea, bloody stools, weight loss, severe colonic inflammation, and ulceration. Despite the increase in the frequency of UC and the deterioration of the quality of life, there are still patients who do not respond well to available treatment options...
November 2023: Food Research International
#17
JOURNAL ARTICLE
Albert Katchborian-Neto, Karen de Jesus Nicácio, Jonas C Cruz, Paula Carolina Pires Bueno, Michael Murgu, Danielle F Dias, Marisi G Soares, Ana C C Paula, Daniela A Chagas-Paula
BACKGROUND: Species within the Ocotea genus (Lauraceae), have demonstrated an interesting profile of bioactivities. Renowned for their diverse morphology and intricate specialized metabolite composition, Ocotea species have re-emerged as compelling candidates for bioprospecting in drug discovery research. However, it is a genus insufficiently studied, particularly regarding anti-inflammatory activity. PURPOSE: To investigate the anti-inflammatory activity of Ocotea spp...
November 2023: Phytomedicine
#18
Vinicius Tadeu Ramos da Silva Grillo, Pedro Luciano Mellucci, Marina Moraes Lopes Soares, Nathalia Dias Sertorio, Rodrigo Gibin Jaldin, Marcone Lima Sobreira, Eloisa Bueno Pires de Campos, Matheus Bertanha
The main type of access used for hemodialysis is the arteriovenous fistula (AVF) because it offers superior patency and lower complication rates when compared to other hemodialysis accesses. We report the case of a 69-year-old female patient with chronic kidney disease on dialysis secondary to hypertensive nephrosclerosis with a radiocephalic AVF in the left upper limb created 9 years previously. Two years previously, she had undergone a kidney transplant and was taking immunosuppressants. A crusted lesion developed on her left forearm with onset 3 months before presentation and she underwent an excisional biopsy that revealed a well-differentiated and superficially invasive squamous cell carcinoma, with lateral and deep surgical margins free from neoplasia...
2023: Jornal Vascular Brasileiro
#19
JOURNAL ARTICLE
Marianna de Carvalho Clímaco, Luiza Almeida de Figueiredo, Rayane Cristina Lucas, Guilherme Rafael Gomide Pinheiro, Luísa Mourão Dias Magalhães, Ana Laura Grossi de Oliveira, Raquel Martins Almeida, Fernando Sérgio Barbosa, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Tiago Antonio Mendes, Bin Zhan, Kathryn Marie Jones, Peter Hotez, Maria Elena Bottazzi, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara
Leishmania spp. and Trypanosoma cruzi are parasitic kinetoplastids of great medical and epidemiological importance since they are responsible for thousands of deaths and disability-adjusted life-years annually, especially in low- and middle-income countries. Despite efforts to minimize their impact, current prevention measures have failed to fully control their spread. There are still no vaccines available. Taking into account the genetic similarity within the Class Kinetoplastida, we selected CD8+ T cell epitopes preserved among Leishmania spp...
July 19, 2023: Vaccine
#20
JOURNAL ARTICLE
Carlos Roberto Emerenciano Bueno, Francine Benetti, Marina Tolomei Sandoval Cury, Ana Maria Veiga Vasques, Leopoldo Cosme-Silva, Índia Olinta de Azevedo Queiroz, Ana Cláudia Rodrigues da Silva, Rogério de Castilho Jacinto, Luciano Tavares Angelo Cintra, Eloi Dezan-Junior
The purpose of this study was to evaluate, in vivo, the biocompatibility, biomineralization, collagen maturation and the in vitro antibacterial and cytotoxicity of resinous endodontic sealers containing calcium hydroxide. Forty rats were implanted with polyethylene tubes containing Sealer 26, Sealer Plus, Dia-ProSeal and an empty tube, examined after 7, 15, 30 and 60 days. Antimicrobial activity was evaluated against Enterococcus faecalis by Agar Diffusion Test (ADT) through inhibition zones. For cytotoxicity, undifferentiated pulp cells (OD-21) were cultured and assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, exposed to dilution of serial extracts at 6, 24, 48h...
2023: PloS One
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