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https://www.readbyqxmd.com/read/28570909/raman-spectral-characteristics-of-neck-and-head-of-femur-in-low-density-lipoprotein-receptor-gene-knockout-mice-submitted-to-treadmill-aerobic-training
#1
Gabriela Loiola Camargo, Renato Aparecido de Souza, Dênis Bueno da Silva, José Antônio Dias Garcia, Landulfo Silveira
Hypercholesterolemia is associated with deterioration of bone tissue. Trough Raman spectroscopy, the present study aimed to assess the molecular changes in terms of mineral and organic bone-tissue remodeling in low-density lipoprotein receptor gene knockout mice (LDLr-/-) submitted to treadmill aerobic training. In order to evaluate alterations in trabecular bone and cartilage surface, neck and head femoral were assessed into four groups: (CON, n=7), the 1) animals did not perform any physical activity and had hypercholesterolemia (CON, n=7); The trained groups where animals underwent a protocols of low, moderate and high training for 8weeks and 4 times per week on a treadmill with progressive intensities: running speed (8-13m/min) and time of exercise (20-60min)...
May 16, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28444093/electrical-stimulation-attenuates-morphological-alterations-and-prevents-atrophy-of-the-denervated-cranial-tibial-muscle
#2
Cleuber Rodrigo de Souza Bueno, Mizael Pereira, Idvaldo Aparecido Favaretto, Carlos Henrique Fachin Bortoluci, Thais Caroline Pereira Dos Santos, Daniel Ventura Dias, Letícia Rossi Daré, Geraldo Marco Rosa
Objective: To investigate if electrical stimulation through Russian current is able to maintain morphology of the cranial tibial muscle of experimentally denervated rats. Methods: Thirty-six Wistar rats were divided into four groups: the Initial Control Group, Final Control Group, Experimental Denervated and Treated Group, Experimental Denervated Group. The electrostimulation was performed with a protocol of Russian current applied three times per week, for 45 days...
January 2017: Einstein
https://www.readbyqxmd.com/read/28432734/monogenic-diabetes-syndromes-locus-specific-databases-for-alstr%C3%A3-m-wolfram-and-thiamine-responsive-megaloblastic-anemia
#3
Dewi Astuti, Ataf Sabir, Piers Fulton, Malgorzata Zatyka, Denise Williams, Carol Hardy, Gabriella Milan, Francesca Favaretto, Patrick Yu-Wai-Man, Julia Rohayem, Miguel López de Heredia, Tamara Hershey, Lisbeth Tranebjaerg, Jian-Hua Chen, Annabel Chaussenot, Virginia Nunes, Bess Marshall, Susan McAfferty, Vallo Tillmann, Pietro Maffei, Veronique Paquis-Flucklinger, Tarekign Geberhiwot, Wojciech Mlynarski, Kay Parkinson, Virginie Picard, Gema Esteban Bueno, Renuka Dias, Amy Arnold, Caitlin Richens, Richard Paisey, Fumihiko Urano, Robert Semple, Richard Sinnott, Timothy G Barrett
We developed a variant database for diabetes syndrome genes, using the Leiden Open Variation Database platform, containing observed phenotypes matched to the genetic variations. We populated it with 628 published disease-associated variants (December 2016) for: WFS1 (n = 309), CISD2 (n = 3), ALMS1 (n = 268), and SLC19A2 (n = 48) for Wolfram type 1, Wolfram type 2, Alström, and Thiamine-responsive megaloblastic anemia syndromes, respectively; and included 23 previously unpublished novel germline variants in WFS1 and 17 variants in ALMS1...
July 2017: Human Mutation
https://www.readbyqxmd.com/read/28421789/in%C3%AF-uencia-del-aceite-de-coco-en-enfermos-de-alzh%C3%A3-imer-a-nivel-cognitivo
#4
José Enrique De la Rubia Ortí, Carmen Sánchez Álvarez, Pablo Selvi Sabater, Alma María Bueno Cayo, Sandra Sancho Castillo, Mariano Julián Rochina, Iván Hu Yang
Introducción: la enfermedad de Alzheimer es a día de hoy la demencia neurodegenerativa con mayor prevalencia en el primer mundo. Este hecho, unido a la falta de tratamiento farmacológico que cure la enfermedad, hace que se estudien nuevas estrategias terapéuticas no farmacológicas como es la administración de nutrientes. En este sentido, destaca la posible influencia del aceite de coco como fuente energética alternativa, capaz de frenar la muerte neuronal que se produce de modo progresivo en esta enfermedad...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28271525/survey-of-malassezia-sp-and-dermatophytes-in-the-cutaneous-microbiome-of-free-ranging-golden-headed-lion-tamarins-leontopithecus-chrysomelas-kuhl-1820
#5
Juan Ja Neves, Marcelo Francelino, Flavia Gl Silva, Luana Cl Baptista, Marina G Bueno, José L Catão-Dias, Camila Molina, Maria Cm Kierulff, Alcides Pissinatti, Selene DA Coutinho
BACKGROUND: Data about the presence of fungi on the cutaneous surface of wild animals are scarce. The aim of this study was to survey dermatophytes and Malassezia sp in the external ear canal and haircoat of Leontopithecus chrysomelas. METHODS: A total of 928 clinical samples were collected from 232 animals: For Malassezia screening 696 samples were studied, 464 of cerumen and 232 of haircoat; another 232 haircoat samples were studied for dermatophyte analysis. RESULTS: A geophilic dermatophyte, Microsporum cookie, was isolated from one young female...
June 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/28060137/infants-with-congenital-zika-syndrome-and-ocular-findings-from-s%C3%A3-o-paulo-brazil-spread-of-infection
#6
João Rafael de Oliveira Dias, Camila V Ventura, Paula Delegrego Borba, Bruno de Paula Freitas, Ligia Camera Pierroti, Ana Patricia do Nascimento, Nilva Simeren Bueno de Moraes, Maurício Maia, Rubens Belfort
BACKGROUND/PURPOSE: To describe the ocular findings of two infants with congenital Zika syndrome born in São Paulo state, Brazil, outside the primary outbreak region. METHODS: Two female infants with congenital Zika syndrome were submitted to a complete screening for infectious diseases, as well as ocular examination, fundus photography, and optical coherence tomography of the retina. One of the infants was submitted to ocular ultrasound. RESULTS: Both children showed positive serology for Zika virus, and other infectious diseases were ruled out...
January 2, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27925063/negative-serosurvey-of-toxoplasma-gondii-antibodies-in-golden-headed-lion-tamarin-leontopithecus-chrysomelas-from-niter%C3%A3-i-rj-brazil
#7
Camila Vieira Molina, Felipe da Silva Krawczak, Marina Galvão Bueno, Herbert Sousa Soares, Solange Maria Genari, Alcides Pissinatti, Maria Cecília Martins Kierulff, Tiago Ferreira da Silva, Danilo Gomes de Freitas, Larissa Cristinne Caneli, José Luiz Catão-Dias
New World Nonhuman Primates are highly susceptible to clinical toxoplasmosis. Serum samples from 126 recently captured Leontopithecus chrysomelas, from an exotic and invasive population, were tested for Toxoplasma gondii antibodies by the modified agglutination test (MAT, cut-off 1:25); all were seronegative. The MAT is highly specific and is not species-specific. This is the first report of T. gondii survey in this tamarin in the wild. This result is consistent with prior reports that showed the high susceptibility of the species to infection by T...
January 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/27557020/to-donate-or-not-donate-that-is-the-question-an-analysis-of-the-critical-factors-of-blood-donation
#8
Jefferson Rodrigues Pereira, Caissa Veloso E Sousa, Eliane Bragança de Matos, Leonardo Benedito Oliveira Rezende, Natália Xavier Bueno, Álvaro Machado Dias
Currently, in Brazil, 1.78% of the population area blood donors, a level lower than the ideal one that, according to WHO, should be between 3% and 5% of the population. Following this scenario, the current study has a general goal of identifying and analyzing the main critical factors of the process of blood donation in the city of Belo Horizonte, MG, under the perception of donors, potential donors and non donors. A qualitative research approach was conducted, through twenty-four semi-structured interviews...
August 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27527890/pleural-effusion-with-negative-culture-a-challenge-for-pneumococcal-diagnosis-in-children
#9
Vinicius Pieta Perez, Juliana Caierão, Gilberto Bueno Fischer, Cícero Armídio Gomes Dias, Pedro Alves d'Azevedo
BACKGROUND: Pneumococcal parapneumonic effusion seems to be increasing in children in the postvaccine era and is frequently associated with negative culture. Due to the low yield of culture, culture-independent tools are evaluated. METHODS: Culture-negative pleural fluid specimens from 38 children with parapneumonic effusion were examined for pneumococcal lytA by quantitative polymerase chain reaction (qPCR) and soluble antigen (C-polysaccharide) using an immunochromatographic test (BinaxNow Streptococcus pneumoniae)...
October 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27149618/the-postpharyngeal-gland-specialized-organ-for-lipid-nutrition-in-leaf-cutting-ants
#10
Pâmela Decio, Alexsandro Santana Vieira, Nathalia Baptista Dias, Mario Sergio Palma, Odair Correa Bueno
There are several hypotheses about the possible functions of the postpharyngeal gland (PPG) in ants. The proposed functions include roles as cephalic or gastric caeca and diverticulum of the digestive tract, mixing of hydrocarbons, nestmate recognition, feeding larvae, and the accumulation of lipids inside this gland, whose origin is contradictory. The current study aimed to investigate the functions of these glands by examining the protein expression profile of the PPGs of Atta sexdens rubropilosa (Hymenoptera, Formicidae)...
2016: PloS One
https://www.readbyqxmd.com/read/27112578/the-new-heterologous-fibrin-sealant-in-combination-with-low-level-laser-therapy-lllt-in-the-repair-of-the-buccal-branch-of-the-facial-nerve
#11
Daniela Vieira Buchaim, Antonio de Castro Rodrigues, Rogerio Leone Buchaim, Benedito Barraviera, Rui Seabra Ferreira Junior, Geraldo Marco Rosa Junior, Cleuber Rodrigo de Souza Bueno, Domingos Donizeti Roque, Daniel Ventura Dias, Leticia Rossi Dare, Jesus Carlos Andreo
This study aimed to evaluate the effects of low-level laser therapy (LLLT) in the repair of the buccal branch of the facial nerve with two surgical techniques: end-to-end epineural suture and coaptation with heterologous fibrin sealant. Forty-two male Wistar rats were randomly divided into five groups: control group (CG) in which the buccal branch of the facial nerve was collected without injury; (2) experimental group with suture (EGS) and experimental group with fibrin (EGF): The buccal branch of the facial nerve was transected on both sides of the face...
July 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/26883507/survey-of-plasmodium-in-the-golden-headed-lion-tamarin-leontopithecus-chrysomelas-living-in-urban-atlantic-forest-in-rio-de-janeiro-brazil
#12
Elizabeth Helen Aitken, Marina Galvão Bueno, Luana Dos Santos Ortolan, José M Alvaréz, Alcides Pissinatti, Maria Cecília Martins Kierulff, José Luiz Catão-Dias, Sabrina Epiphanio
BACKGROUND: Communicating the presence of potential zoonotic pathogens such as Plasmodium spp. in wild animals is important for developing both animal and human health policies. METHODS: The translocation of an exotic and invasive population of Leontopithecus chrysomelas (golden-headed lion tamarins) required the screening of these animals for specific pathogens. This studies objective was to investigate Plasmodium spp. infection in the L. chrysomelas, both to know its prevalence in these animals in the local area and to minimize the risk of pathogens being translocated to the destination site...
February 17, 2016: Malaria Journal
https://www.readbyqxmd.com/read/26685992/reciprocal-activation-inactivation-of-erk-in-the-amygdala-and-frontal-cortex-is-correlated-with-the-degree-of-novelty-of-an-open-field-environment
#13
Frederico Velasco Sanguedo, Caio Vitor Bueno Dias, Flavia Regina Cruz Dias, Richard Ian Samuels, Robert J Carey, Marinete Pinheiro Carrera
RATIONALE: Phosphorylated extracellular signal-regulated kinase (ERK) has been used to identify brain areas activated by exogenous stimuli including psychostimulant drugs. OBJECTIVE: Assess the role of the amygdala in emotional responses. METHODS: Experimental manipulations were performed in which environmental familiarity was the variable. To provide the maximal degree of familiarity, ERK was measured after removal from the home cage and re-placement back into the same cage...
March 2016: Psychopharmacology
https://www.readbyqxmd.com/read/26607939/nutrient-wide-association-study-of-57-foods-nutrients-and-epithelial-ovarian-cancer-in-the-european-prospective-investigation-into-cancer-and-nutrition-study-and-the-netherlands-cohort-study
#14
Melissa A Merritt, Ioanna Tzoulaki, Piet A van den Brandt, Leo J Schouten, Konstantinos K Tsilidis, Elisabete Weiderpass, Chirag J Patel, Anne Tjønneland, Louise Hansen, Kim Overvad, Mathilde His, Laureen Dartois, Marie-Christine Boutron-Ruault, Renée T Fortner, Rudolf Kaaks, Krasimira Aleksandrova, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Christina Bamia, Domenico Palli, Vittorio Krogh, Rosario Tumino, Fulvio Ricceri, Amalia Mattiello, H Bas Bueno-de-Mesquita, N Charlotte Onland-Moret, Petra H Peeters, Guri Skeie, Mie Jareid, J Ramón Quirós, Mireia Obón-Santacana, María-José Sánchez, Saioa Chamosa, José M Huerta, Aurelio Barricarte, Joana A Dias, Emily Sonestedt, Annika Idahl, Eva Lundin, Nicholas J Wareham, Kay-Tee Khaw, Ruth C Travis, Pietro Ferrari, Elio Riboli, Marc J Gunter
BACKGROUND: Studies of the role of dietary factors in epithelial ovarian cancer (EOC) development have been limited, and no specific dietary factors have been consistently associated with EOC risk. OBJECTIVE: We used a nutrient-wide association study approach to systematically test the association between dietary factors and invasive EOC risk while accounting for multiple hypothesis testing by using the false discovery rate and evaluated the findings in an independent cohort...
January 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26587266/tiarajudens-eccentricus-and-anomocephalus-africanus-two-bizarre-anomodonts-synapsida-therapsida-with-dental-occlusion-from-the-permian-of-gondwana
#15
Juan Carlos Cisneros, Fernando Abdala, Tea Jashashvili, Ana de Oliveira Bueno, Paula Dentzien-Dias
Anomodontia was a highly successful tetrapod clade during the Permian and the Triassic. New morphological information regarding two bizarre basal anomodonts is provided and their palaeoecological significance is explored. The osteology of the recently discovered Tiarajudens eccentricus Cisneros et al. 2011, from the Brazilian Permian, is described in detail. The taxon exhibits unusual postcranial features, including the presence of gastralia. Additional preparation and computed tomography scans of the holotype of Anomocephalus africanus Modesto et al...
July 2015: Royal Society Open Science
https://www.readbyqxmd.com/read/26554655/reproductive-factors-and-epithelial-ovarian-cancer-survival-in-the-epic-cohort-study
#16
Jelena Bešević, Marc J Gunter, Renée T Fortner, Konstantinos K Tsilidis, Elisabete Weiderpass, N Charlotte Onland-Moret, Laure Dossus, Anne Tjønneland, Louise Hansen, Kim Overvad, Sylvie Mesrine, Laura Baglietto, Françoise Clavel-Chapelon, Rudolf Kaaks, Krasimira Aleksandrova, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Christina Bamia, Giovanna Masala, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Salvatore Panico, H Bas Bueno-de-Mesquita, Petra H Peeters, Mie Jareid, J Ramón Quirós, Eric J Duell, María-José Sánchez, Nerea Larrañaga, María-Dolores Chirlaque, Aurelio Barricarte, Joana A Dias, Emily Sonestedt, Annika Idahl, Eva Lundin, Nicholas J Wareham, Kay-Tee Khaw, Ruth C Travis, Sabina Rinaldi, Isabelle Romieu, Elio Riboli, Melissa A Merritt
BACKGROUND: Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025 invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included 521,330 total participants (approximately 370,000 women) aged 25-70 years at recruitment from 1992 to 2000...
December 1, 2015: British Journal of Cancer
https://www.readbyqxmd.com/read/26327119/insights-into-the-microbial-and-viral-dynamics-of-a-coastal-downwelling-upwelling-transition
#17
Gustavo Bueno Gregoracci, Ana Carolina Dos Santos Soares, Milene Dias Miranda, Ricardo Coutinho, Fabiano L Thompson
Although previous studies have described opposing states in upwelling regions, i.e., the rise of cold nutrient-rich waters and prevalence of surface warm nutrient-poor waters, few have addressed the transition from one state to the other. This study aimed to describe the microbial and viral structure during this transition and was able to obtain the taxonomic and metabolic compositions as well as physical-chemical data. This integrated approach allowed for a better understanding of the dynamics of the downwelling upwelling transition, suggesting that a wealth of metabolic processes and ecological interactions are occurring in the minute fractions of the plankton (femto, pico, nano)...
2015: PloS One
https://www.readbyqxmd.com/read/25944744/structure-activity-relationship-of-mastoparan-analogs-effects-of-the-number-and-positioning-of-lys-residues-on-secondary-structure-interaction-with-membrane-mimetic-systems-and-biological-activity
#18
Bibiana Monson de Souza, Marcia Perez Dos Santos Cabrera, Paulo Cesar Gomes, Nathalia Baptista Dias, Rodrigo Guerino Stabeli, Natalia Bueno Leite, João Ruggiero Neto, Mario Sergio Palma
In this study, a series of mastoparan analogs were engineered based on the strategies of Ala and Lys scanning in relation to the sequences of classical mastoparans. Ten analog mastoparans, presenting from zero to six Lys residues in their sequences were synthesized and assayed for some typical biological activities for this group of peptide: mast cell degranulation, hemolysis, and antibiosis. In relation to mast cell degranulation, the apparent structural requirement to optimize this activity was the existence of one or two Lys residues at positions 8 and/or 9...
October 2015: Peptides
https://www.readbyqxmd.com/read/25943130/pneumonia-and-bacteremia-in-a-golden-headed-lion-tamarin-leontopithecus-chrysomelas-caused-by-klebsiella-pneumoniae-subsp-pneumoniae-during-a-translocation-program-of-free-ranging-animals-in-brazil
#19
Marina G Bueno, Renata O Iovine, Luciana N Torres, José L Catão-Dias, Alcides Pissinatti, Maria C M Kierulff, Vania M Carvalho
Klebsiella pneumoniae is an important emerging pathogen in humans, particularly the invasive hypermucoviscosity (HMV) phenotype. In addition, the organism is an important public health concern because of nosocomial infections and antimicrobial resistance. Nonhuman primates in captivity are susceptible to Klebsiella, particularly when a stress factor is involved. Infections vary depending on the species but can cause significant morbidity and mortality in these animals. The objective of this study was to describe a case of bronchopneumonia and bacteremia caused by Klebsiella pneumoniae in a free-ranging golden-headed lion tamarin (Leontopithecus chrysomelas) caught and maintained in quarantine during a translocation program for conservation purposes...
May 2015: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/25559518/intravitreal-injection-of-ziv-aflibercept-in-patient-with-refractory-age-related-macular-degeneration
#20
João Rafael de Oliveira Dias, Camilla Oliveira Xavier, André Maia, Nilva Simeren Bueno de Moraes, Carsten Meyer, Michel Eid Farah, Eduardo Büchele Rodrigues
The results of a patient with exudative age-related macular degeneration who received an intravitreal injection of ziv-aflibercept (Zaltrap; Sanofi-Aventis, Paris, France) in the right eye are described. A complete ocular examination as well as color fundus photography, optical coherence tomography, fluorescein angiography, microperimetry, full-field electroretinography, and multifocal electroretinography were performed and repeated 1 month later. The patient experienced subjective and objective improvement of visual acuity with a decrease in intraretinal and subretinal fluid...
January 2015: Ophthalmic Surgery, Lasers & Imaging Retina
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