Cecilia A Hinojosa, Amanda Liew, Xinming An, Jennifer S Stevens, Archana Basu, Sanne J H van Rooij, Stacey L House, Francesca L Beaudoin, Donglin Zeng, Thomas C Neylan, Gari D Clifford, Tanja Jovanovic, Sarah D Linnstaedt, Laura T Germine, Scott L Rauch, John P Haran, Alan B Storrow, Christopher Lewandowski, Paul I Musey, Phyllis L Hendry, Sophia Sheikh, Christopher W Jones, Brittany E Punches, Michael C Kurz, Robert A Swor, Lauren A Hudak, Jose L Pascual, Mark J Seamon, Elizabeth M Datner, Anna M Chang, Claire Pearson, David A Peak, Roland C Merchant, Robert M Domeier, Niels K Rathlev, Paulina Sergot, Leon D Sanchez, Steven E Bruce, Mark W Miller, Robert H Pietrzak, Jutta Joormann, Diego A Pizzagalli, John F Sheridan, Steven E Harte, James M Elliott, Ronald C Kessler, Karestan C Koenen, Samuel A McLean, Kerry J Ressler, Negar Fani
BACKGROUND: Several hypotheses may explain the association between substance use, posttraumatic stress disorder (PTSD), and depression. However, few studies have utilized a large multisite dataset to understand this complex relationship. Our study assessed the relationship between alcohol and cannabis use trajectories and PTSD and depression symptoms across 3 months in recently trauma-exposed civilians. METHODS: In total, 1618 (1037 female) participants provided self-report data on past 30-day alcohol and cannabis use and PTSD and depression symptoms during their emergency department (baseline) visit...
June 13, 2023: Psychological Medicine