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Posttrauma

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https://www.readbyqxmd.com/read/29238636/functional-outcome-of-neurologic-controlled-hal-exoskeletal-neurorehabilitation-in-chronic-spinal-cord-injury-a-pilot-with-one-year-treatment-and-variable-treatment-frequency
#1
Oliver Jansen, Thomas A Schildhauer, Renate C Meindl, Martin Tegenthoff, Peter Schwenkreis, Matthias Sczesny-Kaiser, Dennis Grasmücke, Christian Fisahn, Mirko Aach
Study Design: Longitudinal prospective study. Objectives: Whether 1-year HAL-BWSTT of chronic spinal cord injured patients can improve independent ambulated mobility further as a function of training frequency, after an initial 3-month training period. Methods: Eight patients with chronic SCI were enrolled. They initially received full standard physical therapy and neurorehabilitation in the acute/subacute posttrauma phase. During this trial, all patients first underwent a daily (5 per week) HAL-BWSTT for 12 weeks...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29222622/toll-like-receptor-4-knockdown-attenuates-brain-damage-and-neuroinflammation-after-traumatic-brain-injury-via-inhibiting-neuronal-autophagy-and-astrocyte-activation
#2
Hongsheng Jiang, Yanzhou Wang, Xin Liang, Xiaofeng Xing, Xiuzhen Xu, Caifeng Zhou
Toll-like receptor 4 (TLR4) has been linked to various pathophysiological conditions, such as traumatic brain injury (TBI). It is reported that posttraumatic neuroinflammation is an essential event in the progression of brain injury after TBI. Recent evidences indicate that TLR4 mediates glial phagocytic activity and inflammatory cytokines production. Thus, TLR4 may be an important therapeutic target for neuroinflammatory injury post-TBI. This study was designed to explore potential effects and underlying mechanisms of TLR4 in rats suffered from TBI...
December 8, 2017: Cellular and Molecular Neurobiology
https://www.readbyqxmd.com/read/29170347/50%C3%A2-how-can-informal-support-impact-child-ptsd-symptoms-following-a-psychological-trauma
#3
Sarah Halligan
BACKGROUND: An estimated 20% of children who present to hospital emergency departments following potentially traumatic events (e.g., serious injuries, road traffic accidents, assaults) will develop post-traumatic stress disorder as a consequence. The development of PTSD can have a substantial impact on a child's developmental trajectory, including their emotional, social and educational wellbeing. Despite this, only a small proportion will access mental health services, with the majority relying on informal sources of support...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29154596/the-moderating-role-of-trauma-type-on-the-relationship-between-event-centrality-of-the-traumatic-experience-and-mental-health-outcomes
#4
Rachel Wamser-Nanney, Kathryn H Howell, Laura E Schwartz, Amanda J Hasselle
OBJECTIVE: Event centrality, or the extent to which traumatic events are perceived to be integral to one's life, has been found to be predictive of trauma-related symptoms, such as posttraumatic stress disorder (PTSD) and depression. Less research has been devoted to whether event centrality is related to adaptive outcomes, such as posttraumatic growth (PTG) and resiliency, and psychological well-being (PWB) has not been investigated. Given the unique circumstances of different types of traumas, the relationship between event centrality and posttrauma functioning may differ by the type of trauma experienced...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29154593/shame-and-alienation-related-to-child-maltreatment-links-to-symptoms-across-generations
#5
Rebecca L Babcock Fenerci, Anne P DePrince
OBJECTIVE: The current study investigated associations between appraisals of shame and alienation related to mothers' own experiences of child maltreatment and symptoms across generations-in mothers themselves as well as their toddler/preschool-aged children. METHOD: Mothers who survived maltreatment (N = 113) with a child between the ages of 2 and 5 were recruited to participate in an online study on Maternal Coping, Attachment and Health. Mother participants completed a series of questionnaires, including those that asked about posttrauma appraisals of their own maltreatment experiences as well as their child's and their own mental health symptoms...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29140560/negative-posttrauma-cognitions-mediate-the-association-between-morally-injurious-events-and-trauma-related-psychopathology-in-treatment-seeking-veterans
#6
Philip Held, Brian J Klassen, Denise S Zou, Blake S Schroedter, Niranjan S Karnik, Mark H Pollack, Alyson K Zalta
Exposure to potentially morally injurious events has been shown to be associated with posttraumatic stress disorder (PTSD) and depression symptoms in military personnel. Few studies have examined factors that help to explain how potentially morally injurious events may contribute to the development of trauma-related psychopathology. Negative posttrauma cognitions are thought to play a role in the etiology of PTSD and depression following trauma; however, it is unclear whether more global beliefs about the self, others, and world play a role in the development of PTSD and depression due to morally injurious events...
November 15, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29131332/the-impact-of-rape-acknowledgment-on-survivor-outcomes-the-moderating-effects-of-rape-myth-acceptance
#7
Laura C Wilson, Amie R Newins, Susan W White
OBJECTIVE: Little is known about how rape acknowledgment relates to posttrauma functioning; recent research suggests the effect may depend on additional factors. In the current study, the moderating effect of rape myth acceptance (RMA) on the relationships between rape acknowledgment and mental health outcomes was examined. METHOD: A sample of 181 female rape survivors recruited from a university completed an online survey assessing RMA, rape acknowledgment, depression symptoms, and alcohol use...
November 13, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29114279/comparison-between-ventriculosubgaleal-shunt-and-extraventricular-drainage-to-treat-acute-hydrocephalus-in-adults
#8
Low Siaw Nee, Rahmat Harun, Pulivendhan Sellamuthu, Zamzuri Idris
Context: Hydrocephalus, due to subarachnoid or intraventricular hemorrhage (IVH), meningitis, or tumor compression, is usually transient and may resolve after treatment. There are several temporary methods of cerebrospinal fluid (CSF) diversion, none of it is superior to the other, and the decision is based on its various etiologies and factors. Ventriculosubgaleal shunt (VSGS) is one of those temporary measures, which is a simple and rapid CSF decompression method without causing electrolyte and nutritional losses...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29110899/the-role-of-the-hippocampus-in-predicting-future-posttraumatic-stress-disorder-symptoms-in-recently-traumatized-civilians
#9
Sanne J H van Rooij, Jennifer S Stevens, Timothy D Ely, Rebecca Hinrichs, Vasiliki Michopoulos, Sterling J Winters, Yvonne E Ogbonmwan, Jaemin Shin, Nicole R Nugent, Lauren A Hudak, Barbara O Rothbaum, Kerry J Ressler, Tanja Jovanovic
BACKGROUND: Understanding the neurobiological mechanisms that predict posttraumatic stress disorder (PTSD) in recent trauma survivors is important for early interventions. Impaired inhibition of fear or behavioral responses is thought to be central to PTSD symptomatology, but its role in predicting PTSD is unknown. Here we examine whether brain function during response inhibition early after a civilian trauma can predict future PTSD symptoms. METHODS: Participants (original sample, n = 27; replication sample, n = 31) were recruited in the emergency department within 24 hours of trauma exposure...
September 20, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29109968/tracking-post-trauma-psychopathology-using-mobile-applications-a-usability-study
#10
Matthew Price, Katherine van Stolk-Cooke, Hannah L Ward, Michael O'Keefe, Jennifer Gratton, Christian Skalka, Kalev Freeman
Trauma exposure markedly increases risk for psychopathology including posttraumatic stress disorder (PTSD). Understanding the course by which PTSD develops after a traumatic event is critical to enhancing early intervention. Although prior work has explored the course of PTSD symptoms in the subsequent months, relatively few studies have explored the course of symptoms in the acute post-trauma period, defined as the 30 days after a traumatic event. A key challenge to conducting such studies is the lack of efficient means to collect data that does not impose significant burden on the participant during this time...
March 2017: Journal of Technology in Behavioral Science
https://www.readbyqxmd.com/read/29092624/intergenerational-transmission-of-trauma-maternal-trauma-related-cognitions-and-toddler-symptoms
#11
Rebecca L Babcock Fenerci, Anne P DePrince
The purpose of this study was to elucidate possible cognitive mechanisms involved in the intergenerational transmission of trauma from maltreatment-survivor mothers to their toddler/preschool-aged children. This study investigated whether maternal trauma-related cognitions-posttrauma appraisals and disorganized memory for maltreatment-were associated with higher levels of toddler internalizing and externalizing symptoms and more dysfunction in the mother-child relationship. A community sample of mothers with histories of maltreatment and a child between the ages of 2 and 5 years was recruited for a study on maternal attachment, coping, and health ( N = 113)...
January 1, 2017: Child Maltreatment
https://www.readbyqxmd.com/read/29091828/prospectively-predicting-ptsd-status-with-heart-rate-reactivity-and-recovery-in-interpersonal-violence-survivors
#12
Brittany F Goodman, Michael G Griffin
The current study used heart rate (HR) reactivity to personalized trauma cues and HR recovery to predict later Posttraumatic Stress Disorder (PTSD) status in female interpersonal violence survivors. A scripted imagery paradigm was used to assess initial (M = 1 month posttrauma) HR reactivity during exposure to and recovery following idiographic trauma cues. In addition, follow-up PTSD status (M = 8 months posttrauma) was assessed with the Clinician Administered PTSD scale (CAPS). A logistic regression was used to predict PTSD status at the follow-up assessment with HR reactivity during exposure to a personalized trauma audio script and recovery periods at initial assessment entered hierarchically...
October 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29077999/caregiver-responses-to-child-posttraumatic-distress-a-qualitative-study-in-a-high-risk-context-in-south-africa
#13
Victoria Williamson, Ian Butler, Mark Tomlinson, Sarah Skeen, Hope Christie, Jackie Stewart, Sarah L Halligan
Many low- and middle-income countries (LMIC) have high rates of child trauma exposure and limited access to psychological services. Caregivers are often a child's key source of support following trauma in such contexts. The aim of this study was to explore the experiences of primary caregivers in supporting their child posttrauma. Qualitative interviews were conducted with 20 female caregivers from a high-risk settlement in Cape Town following child trauma exposure. Children were exposed to significant traumatic events, including gang violence, assault, and fatalities of close relatives...
October 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29030878/the-association-between-ptsd-and-functional-outcome-is-mediated-by-perception-of-cognitive-problems-rather-than-objective-neuropsychological-test-performance
#14
Kristin W Samuelson, Linda Abadjian, Joshua T Jordan, Alisa Bartel, Jennifer Vasterling, Karen Seal
Posttraumatic stress disorder (PTSD) has been consistently linked to poorer functional outcomes, including quality of life, health problems, and social and occupational functioning. Less is known about the potential mechanisms by which PTSD leads to poorer functional outcomes. We hypothesized that neurocognitive functioning and perception of cognitive problems would both mediate the relationship between PTSD diagnosis and functioning. In a sample of 140 veterans of the recent wars and conflicts in Iraq and Afghanistan, we assessed PTSD symptoms, history of traumatic brain injury (TBI), depression, self-report measures of quality of life, social and occupational functioning, and reintegration to civilian life, as well as perception of cognitive problems...
October 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29016432/is-systemic-inflammatory-response-syndrome-relevant-to-pulmonary-complications-and-mortality-in-multiply-injured-children
#15
Waleed Al-Mahdi, Mazen M Ibrahim, David A Spiegel, Alexandre Arkader, Michael Nance, Keith Baldwin
BACKGROUND: Systemic inflammatory response syndrome (SIRS) is a well-recognized phenomenon in adult trauma populations. The "initial hit" of the traumatic event is often coupled with a systemic immune response characterized by changes in vital signs and laboratory indicators. A "second hit" from surgery during this time frame often results in acute lung injury, along with deterioration of the patient's clinical condition. We hypothesized that children and adolescents would experience SIRS physiology, but would not experience adult respiratory distress syndrome (ARDS) or "second hit" related death to the extent seen in the adult populations...
October 9, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28932133/retrospective-study-on-sequelae-in-traumatized-permanent-teeth
#16
Fernanda Chiguti Yamashita, Isolde Terezinha Santos Previdelli, Nair Narumi Orita Pavan, Marcos Sérgio Endo
OBJECTIVE: This study aimed to identify possible associations of the presence or absence of posttrauma sequelae with the factors inherent to the traumatized tooth and treatment. MATERIALS AND METHODS: This retrospective study was performed through the evaluation of records and radiographs of a center of reference for dental trauma between January 2008 and December 2014. The factors were analyzed and associated with posttrauma sequelae, such as pulp necrosis and root resorption...
July 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28829346/return-to-sports-after-multiple-trauma-which-factors-are-responsible-results-from-a-17-year-follow-up
#17
Christian D Weber, Klemens Horst, Anthony R Nguyen, Magdalena J Bader, Christian Probst, Boris Zelle, Hans-Christoph Pape, Thomas Dienstknecht
OBJECTIVE: We hypothesize that the majority of polytraumatised patients are unable to maintain their preinjury level of sporting activity, and that musculoskeletal injuries are a major contributing factor. We assessed the impact of such injuries on sporting prowess, with a focus on isolating, particularly debilitating musculoskeletal trauma. METHODS: We conducted a cohort study of 637 patients at a level 1 trauma centre, to assess the long-term outcome of severe trauma on return to sporting activities (RTS)...
September 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28731937/an-adapted-clavien-dindo-scoring-system-in-trauma-as-a-clinically-meaningful-nonmortality-endpoint
#18
MULTICENTER STUDY
David N Naumann, Laura E Vincent, Nicola Pearson, Alastair Beaven, Iain M Smith, Kieran Smith, Emma Toman, Helen R Dorrance, Keith Porter, Charles E Wade, Bryan A Cotton, John B Holcomb, Mark J Midwinter
BACKGROUND: There is no consensus on reporting nonmortality trauma complications in a graded manner. The Clavien-Dindo scale of complications was originally for elective surgery and requires adaptation to provide meaningful data for trauma patients. In particular, the original score does not account for those treated without surgery. We report an adapted Clavien-Dindo in trauma (ACDiT) scale and apply it to patients managed operatively and nonoperatively. METHODS: A combined prospective and retrospective international multicenter observational study was undertaken to apply the ACDiT scale to 484 trauma patients at three university teaching hospitals (Birmingham, England (n = 303); Houston, Texas (n = 113); and Glasgow, Scotland (n = 68))...
August 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28666398/how-do-we-meet-the-challenge-of-whiplash
#19
EDITORIAL
James M Elliott, David M Walton
A previous special issue of JOSPT (October 2016) discussed whiplash in terms of the clinical problems and current research surrounding prevention, biomechanics of injury, emergent care, imaging advancements, recovery pathways and prognosis, pathogenesis of posttrauma pain, acute and chronic management, and new predictive clinical tools. While great strides have been made in the field of whiplash and are continuing in earnest, a key group of clinicians and academics have recognized that inconsistent outcomes in published literature hamper our ability to meaningfully synthesize research findings, leading to results of systematic reviews that provide very few concrete clinical recommendations...
July 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28661975/interleukin-6-serum-levels-correlate-with-severity-of-burn-injury-but-not-with-gender
#20
Stephan Hager, Ann Christina Foldenauer, Hans-Oliver Rennekampff, Robert Deisz, Ruedger Kopp, Mayer Tenenhaus, Marx Gernot, Norbert Pallua
Gender-specific differences in the outcome of patients with burn injury have been recognized in the past with female patients being at a higher risk of mortality. We hypothesized that early post-burn interleukin-6 (IL-6) cytokine levels may contribute to the different gender-specific outcome. We retrospectively examined 94 burned patients who were treated in the Burn Intensive Care Unit at the University Hospital Aachen. Age, gender, presence of inhalation injury, depth, TBSA, and clinical outcome were documented...
June 21, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
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