Koen P Grootens, Anna Meijer, Erwin G Hartong, Bennard Doornbos, P Roberto Bakker, Asmar Al Hadithy, Kirsten N Hoogerheide, Frans Overmeire, Radboud M Marijnissen, Henricus G Ruhe
OBJECTIVE: To present up-to-date information and recommendations on the management of body weight changes during the use of antiepileptic mood stabilizers in bipolar disorder to help clinicians and patients make well-informed, practical decisions. DATA SOURCES: Umbrella review. Systematic reviews and meta-analyses on the prevention, treatment, and monitoring of body weight changes as a side effect of the mood stabilizers valproate, lamotrigine, topiramate, and carbamazepine were identified in Embase (2010-2015, no language restrictions)...
November 2018: European Journal of Clinical Pharmacology