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https://read.qxmd.com/read/37257486/effects-of-weight-loss-and-interaction-with-physical-activity-on-risks-of-cardiovascular-outcomes-in-individuals-with-type-2-diabetes
#1
JOURNAL ARTICLE
Claudia R L Cardoso, Nathalie C Leite, Gil F Salles
BACKGROUND: This study investigated the effects of weight loss during follow-up on cardiovascular outcomes in a type 2 diabetes cohort and tested interactions with clinical and laboratory variables, particularly physical activity, that could impact the associations. METHODS: Relative weight changes were assessed in 651 individuals with type 2 diabetes and categorized as ≥5% loss, <5% loss, or gain. Associations between weight loss categories and incident cardiovascular outcomes (total cardiovascular events [CVEs], major adverse cardiovascular events [MACEs], and cardiovascular mortality) were assessed using multivariable Cox regression with interaction analyses...
May 31, 2023: Endocrinology and Metabolism
https://read.qxmd.com/read/36541908/-weigth-loss-in-a-neonate-a-case-of-hypoaldosteronism
#2
JOURNAL ARTICLE
Ivar Saevarsson, Soffia Gudrun Jonasdottir, Berglind Jonsdottir
The Neonatal weight loss is a common problem which most physicians who take care of newborns should recognise. The most common reason is insufficient dietary intake. However the reason can also be an underlying disease. Aldosterone insufficiency in neonates is a rare disease and if not treated correctly can be life threatening. It presents with serious electrolytes abnormalities and metabolic acidosis. It is therefore important to distinguish between serious and benign causes of weight loss in neonates.
January 2023: Læknablađiđ
https://read.qxmd.com/read/33253089/secukinumab-s-effect-on-structural-damage-progression-in-psoriatic-arthritis-longitudinal-mixture-modelling-of-future-1-and-future-5
#3
JOURNAL ARTICLE
Olivier Luttringer, Todd Fox, Luminita Pricop, Corine Gaillez, Helene Karcher, Witold Wiecek, Zuzanna Angehrn, Billy Amzal
OBJECTIVES: Peripheral and axial manifestations of psoriatic arthritis (PsA) can lead to irreversible structural damage and chronic disability. Our objective was to explore predictors of radiographic progression and to increase our understanding of treatment effects in subgroups of patients with different rates of structural damage progression. METHODS: We analysed data from two large Phase-3 trials of secukinumab in PsA patients, FUTURE-1 (NCT01392326, n=606) and FUTURE-5 (NCT02404350, n=996), where different posologies ranging from 75 mg to 300 mg were used...
November 17, 2020: Clinical and Experimental Rheumatology
https://read.qxmd.com/read/31174953/dysbiosis-of-gut-microbiota-in-a-selected-population-of-parkinson-s-patients
#4
JOURNAL ARTICLE
Daniele Pietrucci, Rocco Cerroni, Valeria Unida, Alessio Farcomeni, Mariangela Pierantozzi, Nicola Biagio Mercuri, Silvia Biocca, Alessandro Stefani, Alessandro Desideri
INTRODUCTION: In recent years the hypothesis that gut microbiota associates with Parkinson's disease (PD) has gained importance, although it has not been possible to define a specific microbiota composition as a predictive biomarker of this disease. We have investigated dysbiosis of gut microbiota in a selected population of PD patients from Central Italy, and examined the weight of specific confounders and predictors, in order to identify potential correlations with clinical phenotypes...
June 3, 2019: Parkinsonism & related Disorders
https://read.qxmd.com/read/30083876/weight-changes-associated-with-antiepileptic-mood-stabilizers-in-the-treatment-of-bipolar-disorder
#5
JOURNAL ARTICLE
Koen P Grootens, Anna Meijer, Erwin G Hartong, Bennard Doornbos, P Roberto Bakker, Asmar Al Hadithy, Kirsten N Hoogerheide, Frans Overmeire, Radboud M Marijnissen, Henricus G Ruhe
OBJECTIVE: To present up-to-date information and recommendations on the management of body weight changes during the use of antiepileptic mood stabilizers in bipolar disorder to help clinicians and patients make well-informed, practical decisions. DATA SOURCES: Umbrella review. Systematic reviews and meta-analyses on the prevention, treatment, and monitoring of body weight changes as a side effect of the mood stabilizers valproate, lamotrigine, topiramate, and carbamazepine were identified in Embase (2010-2015, no language restrictions)...
November 2018: European Journal of Clinical Pharmacology
https://read.qxmd.com/read/25600157/depressive-symptoms-in-parkinson-s-disease-are-related-to-decreased-hippocampus-and-amygdala-volume
#6
JOURNAL ARTICLE
Tom J van Mierlo, Chin Chung, Elisabeth M Foncke, Henk W Berendse, Odile A van den Heuvel
Depression and anxiety are common in Parkinson's disease (PD), and are among the non-motor symptoms that interfere with quality of life dramatically. Motor, cognitive, and affective features overlap in PD, hampering diagnosis. To shed more light on the contribution of structural brain changes to the presence of PD-related depressive symptoms, we conducted a Voxel-Based Morphometry (VBM) study. We hypothesized that depressive symptoms in PD are related to regional gray matter (GM) volume loss within the limbic circuit...
February 2015: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/21892560/systematic-review-of-the-clinical-efficacy-of-sibutramine-and-orlistat-in-weigth-loss-quality-of-life-and-its-adverse-effects-in-obese-adolescents
#7
REVIEW
E García Díaz, T Martín Folgueras
INTRODUCTION: The prevalence of obesity, a serious public health problem, is increasing among teenagers and thus also increases cardiovascular morbidity and mortality in adulthood. OBJECTIVE: To provide a systematic review of the best evidence about the effect of sibutramine and orlistat in weight loss, quality of life and its adverse effects in adolescents diagnosed with obesity. METHODS: We searched electronic databases and bibliographies of selected articles were inspected for any further reference...
May 2011: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/19116678/-kommerell-diverticula-associated-with-dysphagia-a-clinical-case-and-review-of-the-literature
#8
REVIEW
Ricardo Ferreira, Javier Gallego, J Roque, R A Pereira, M Mendes, A Nobre, J Cravino
We report the case of a young female with disphagia and weigth loss caused by a vascular ring associated with right aortic arch, Kommerell diverticula, and left retroesophageal ligamentum arteriosum (ductus arteriosus). The patient underwent surgical treatment. A left thoracotomy was performed. Surgical technique included diverticulum ressection and an aortopexia. There were no major complications. We also discuss the incidence, pathology, diagnosis, clinical features and treatment of this rare disease.
July 2008: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://read.qxmd.com/read/18401970/effects-of-lifestyle-modification-on-adipocytokine-levels-in-obese-patients
#9
JOURNAL ARTICLE
D A De Luis, R Aller, O Izaola, M Gonzalez Sagrado, R Conde, J L Perez Castrillon
OBJECTIVE: Adipose tissue is considered an active secretory organ of adipocytokines. The principal aim of our study was to examine the changes in adipocytokines levels after weigth reduction in obese patients. MATERIALS AND METHODS: A population of 126 obese (body mass index > 30) non-diabetic outpatients was analyzed in a prospective way. Before and after three months of a lifestyle modification program, an indirect calorimetry, a tetrapolar electrical bioimpedance, blood pressure, a serial assessment of nutritional intake with 3 days written food records and a series of biochemical analyses were performed...
January 2008: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/16278036/differences-in-glycaemic-status-do-not-predict-weight-loss-in-response-to-hypocaloric-diets-in-obese-patients
#10
JOURNAL ARTICLE
D A de Luis, R Aller, O Izaola, M Gonzalez Sagrado, R Conde
OBJECTIVE: The aim of our study was to detect differences in weigth loss with a hypocaloric diet in obese patients depending on their glycaemic status. SUBJECTS AND METHODS: A population of 76 obesity outpatients was analysed in a prospective way. The following variables were specifically recorded at basal time and after 3 months of hypocaloric diet (1200 kcal/day): weight, blood pressure, body mass index (BMI), waist circumference, and waist-hip ratio. Basal glucose, insulin, fibrinogen, cortisol, c-reactive protein, total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides blood levels were measured...
February 2006: Clinical Nutrition
https://read.qxmd.com/read/12138389/-mycobacterium-avium-intracellular-duodenitis-in-an-aids-patients
#11
José Ruiz, Gloria Vargas, Aldo Vivar, Eduardo Sánchez, Ernesto Nava
Mycobacterium avium Intracellulare is a significant pathogen in immunocompromised patients.We present a male patient, 37 years old, HIV(positive) since 1998 with clinical history of chronic diarrhea and weigth loss. On December 1999 he was seen on the Gastroenterology service of Arzobispo Loayza Hospital. He was found to have esophageal candidiasis and Mycobacterium avium Intracellular in his duodenum.The epidemiological, clinical, endoscopy and pathological features are reviewed in this special way of presentation, the association between AIDS and MAI...
January 2000: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://read.qxmd.com/read/632167/sweating-response-in-man-during-transient-rises-of-air-temperature
#12
JOURNAL ARTICLE
J P Libert, V Candas, J J Vogt
Nude men were exposed to neutral environments (Ta = 28 degrees C, Pw = 20 mbar) changing to warm environments (Ta = 50 degrees C, Pw = 20 mbar). The transient period from neutral to warm environment lasted 4 min (dTA/DT = 5.50 degrees C/min) or 20 min (DTa/dt = 1.10 degrees C/min) or 40 min (dTa/dt = 0.55 degrees C/min) or 60 min (dTa/dt = 0.37 degrees C/min). Continuous measurements were made of rectal and mean skin temperatures and of body weigth loss. Sweating started before appreciable variation in rectal temperature...
February 1978: Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
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