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F Sancassiani, Mauro G Carta, Roberta Montisci, Antonio Preti, Sergio Machado, Maria F Moro, Maria F Marchetti, Luigi Meloni
Background: The aim was to study the association between mood and anxiety disorders and the Tako-Tsubo Syndrome (TTS) and to determine the role of antidepressants and the impairment of quality of life due the comorbid psychiatric disorder. Methods: Case-control study: 19 consecutive patients (17 female) with TTS compared to 76 controls without TTS, were randomly selected from the database of a nationwide epidemiological study after matching (gender, age and residence) by controls...
2018: Clinical Practice and Epidemiology in Mental Health: CP & EMH
Michael Böhm, Victoria L Cammann, Jelena R Ghadri, Christian Ukena, Sebastiano Gili, Davide Di Vece, Ken Kato, Katharina J Ding, Konrad A Szawan, Jozef Micek, Stjepan Jurisic, Fabrizio D'Ascenzo, Antonio H Frangieh, Delia Rechsteiner, Burkhardt Seifert, Frank Ruschitzka, Thomas Lüscher, Christian Templin
AIMS: The present study aimed to determine the prognostic impact of resting heart rate (HR) and systolic blood pressure (SBP) in takotsubo syndrome (TTS). METHODS AND RESULTS: Patients from the International Takotsubo Registry with complete data on HR and SBP were enrolled. We analysed all-cause mortality and major adverse cardiac and cerebrovascular events (MACCE) in tertiles of HR (<77 b.p.m., 77-94 b.p.m., >94 b.p.m.) and SBP (<119 mmHg, 119-140 mmHg, >140 mmHg)...
March 8, 2018: European Journal of Heart Failure
Mika Watanabe, Masaki Izumo, Yoshihiro J Akashi
Takotsubo cardiomyopathy is described as a transient reversible cardiomyopathy which typically occurs in older women after emotional or physical stress. This cardiomyopathy is also recognized as a "syndrome" because it develops in conjunction with various diseases. Since the clinical presentation of takotsubo syndrome (TTS) is similar to acute coronary syndrome (ACS), TTS should be distinguished from ischemic heart disease. Although the pathophysiology of TTS has not well been established, a number of its specific features have been suggested...
March 5, 2018: International Heart Journal
Agnieszka Kołodzińska, Katarzyna Czarzasta, Benedykt Szczepankiewicz, Renata Główczyńska, Anna Fojt, Tomasz Ilczuk, Monika Budnik, Krzysztof Krasuski, Miłosz Folta, Agnieszka Cudnoch-Jędrzejewska, Barbara Górnicka, Grzegorz Opolski
AIMS: Toll-like receptors (TLR) and apoptosis were indicated as important factors in heart failure. Our aim was to characterize the morphological pattern of apoptosis, TLR2, TLR4, and TLR6 expression in female rat hearts in the model of takotsubo syndrome (TTS). MAIN METHODS: 60 Sprague-Dawley female rats were treated with a single dose of 150 mg/kg b.wt. of isoprenaline (ISO) or 0.9% NaCl (controls). Hearts were collected 24, 48, 72 h and 7 days post-ISO injection...
March 1, 2018: Life Sciences
Francesco Craig, Alessandro Lorenzo, Elisabetta Lucarelli, Luigi Russo, Isabella Fanizza, Antonio Trabacca
This study aimed to investigate the association between motor competency and social communication in children with Autism Spectrum Disorder (ASD) compared with children with Intellectual Disabilities (ID) and typically developing (TD) children. Motor competency, ASD symptoms, and nonverbal Intelligent Quotient (IQ) were investigated through the following tests: Movement Assessment Battery for Children, second edition (MABC-2), Social Communication Questionnaire (SCQ), Autism Classification System of Functioning: Social Communication (ACSF:SC) and Leiter International Performances Scale Revised (Leiter-R)...
March 1, 2018: Autism Research: Official Journal of the International Society for Autism Research
Meredith G Mock, Katie R Hirsch, Malia N M Blue, Eric T Trexler, Erica J Roelofs, Abbie E Smith-Ryan
The current study sought to evaluate the effects of post-exercise ingestion of a high molecular weight glucose polymer solution (HMW) compared to an isocaloric low molecular weight solution (LMW) or placebo (PLA) on subsequent cycling performance in female athletes. In a randomized, double-blind, placebo-controlled, cross-over design, 10 competitive female cyclists (Mean ± SD; Age = 25.7 ± 5.0 yrs; VO2peak = 49.7 ± 4.3 ml[BULLET OPERATOR]kg[BULLET OPERATOR]min) completed three testing sessions separated by 7-10 days...
February 27, 2018: Journal of Strength and Conditioning Research
Xu Bi, Bo Li, Qi Fu, Yao Fan, Lingxiao Ma, Zihan Yang, Bo Nan, Xuhuan Dai, Xinshi Zhang
Grazing exclusion has been proposed as a method of restoring degraded grassland ecosystems. However, its effectiveness remains poorly understood in mountain-basin grasslands in arid regions. Thus, we investigated the plant community characteristics, C and N storage levels, and soil organic carbon and total nitrogen concentrations and storage within the upper 0-40 cm soil layer in a grazed grassland (GG) and a fenced grassland (FG) with grazing exclusion in mountain meadow (MM) and temperate typical steppe (TTS) habitats in a mountain-basin ecosystem in an arid region of Central China, which are both vital grassland resources for livestock grazing and ecological conservation...
February 22, 2018: Science of the Total Environment
Luisa F Castiblanco, Lindsay R Triplett, George W Sundin
Type III secretion (TTS) chaperones are critical for the delivery of many effector proteins from Gram-negative bacterial pathogens into host cells, functioning in the stabilization and hierarchical delivery of the effectors to the type III secretion system (TTSS). The plant pathogen Erwinia amylovora secretes at least four TTS effector proteins: DspE, Eop1, Eop3, and Eop4. DspE specifically interacts with the TTS chaperone protein DspF, which stabilizes the effector protein in the cytoplasm and promotes its efficient translocation through the TTSS...
2018: Frontiers in Microbiology
Thomas Stiermaier, Francesco Santoro, Ibrahim El-Battrawy, Christian Möller, Tobias Graf, Giuseppina Novo, Andrea Santangelo, Enrica Mariano, Francesco Romeo, Pasquale Caldarola, Mario Fanelli, Holger Thiele, Natale Daniele Brunetti, Ibrahim Akin, Ingo Eitel
OBJECTIVE: In view of low prevalence rates, diabetes is discussed as a protective factor for the occurrence of Takotsubo syndrome (TTS). Furthermore, it was associated with improved outcome in a small single-center analysis. Therefore, this study assessed the prevalence and prognostic relevance of concomitant diabetes in TTS. RESEARCH DESIGN AND METHODS: A total of 826 patients with TTS were enrolled in an international, multicenter, registry-based study (eight centers in Italy and Germany)...
February 15, 2018: Diabetes Care
Nathalie Klopp-Dutote, Catherine Kolski, Vladimir Strunski, Cyril Page
OBJECTIVES: To determine the value of tympanostomy tubes (TTs) in the management of serous otitis media (SOM) and the risk factors for SOM recurrence. METHOD: This single-centre cohort study was performed in the University hospital of Amiens, France; and concerned 215 under-12 children having undergone at least one bilateral TT (Shepard grommet-type) placements for SOM. RESULTS: The mean TT retention time was 10 months. SOM recurred in 79 children (62...
March 2018: International Journal of Pediatric Otorhinolaryngology
Matthew C Hernandez, Moustafah El Khatib, Larry Prokop, Martin D Zielinski, Johnathon M Aho
BACKGROUND: Tube thoracostomy (TT) complications and their reported rates are highly variable (1-40%) and inconsistently classified. Consistent TT complication classification must be applied to compare reported literature to standardize TT placement. We aim to determine the overall TT related complication rates in patients receiving TT for traumatic indications utilizing uniform definitions. METHOD: Systematic review and meta-analysis was performed assessing TT related complications...
February 14, 2018: Journal of Trauma and Acute Care Surgery
Hung-Tao Chen, Robert F Lorch
Text-to-speech (TTS) programs often do a poor job of translating writing devices such as headings from visual into audio mode. Previous research studies have attempted to address this problem but these studies have mainly used heading detection tasks. The current study seeks to investigate (a) whether the presence of audio headings improves performance in natural learning tasks and (b) the type of heading rendering that is the most useful in natural learning tasks. Two experiments compared the effects of two types of rendering strategies on note-taking and cued recall...
February 12, 2018: Journal of Experimental Psychology. Applied
Wei-Liang Loh, Joshua Yi Min Tung, Trevor Hwee Yong Tan, Li Ting Tan, Shaun Tan, Sing Shang Ngoi
INTRODUCTION: Difficult and large common bile duct stones can be crushed and removed using a mechanical lithotripter. Very often the lack of working space within the common bile duct causing the failure of mechanical lithotripsy would inevitably mean repeat or further invasive procedures. PRESENTATION OF CASE: A patient with large and multiple common bile duct stones underwent ERCP, and initial deployment of a mechanical lithotripter failed due to the lack of working space within the common bile duct...
January 24, 2018: International Journal of Surgery Case Reports
Martha Skinner, Sally Eldeghaidy, Rebecca Ford, Timo Giesbrecht, Anna Thomas, Susan Francis, Joanne Hort
Thermal tasters (TTs) perceive thermally induced taste (thermal taste) sensations when the tongue is stimulated with temperature in the absence of gustatory stimuli, while thermal non tasters (TnTs) only perceive temperature. This is the first study to explore detailed differences in thermal taste responses across TTs. Using thermal taster status phenotyping, 37 TTs were recruited, and the temporal characteristics of thermal taste responses collected during repeat exposure to temperature stimulation. Phenotyping found sweet most frequently reported during warming stimulation, and bitter and sour when cooling, but a range of other sensations were stated...
February 1, 2018: Physiology & Behavior
Juntaro Matsumoto, Toyohiko Isu, Kyongsong Kim, Naotaka Iwamoto, Kazuyoshi Yamazaki, Daijiro Morimoto, Masanori Isobe
INTRODUCTION: Some patients suffer failed back surgery syndrome (FBSS) after lumbar spine surgery. We report the effect of additional treatments for para-lumbar- and peripheral nerve diseases addressing residual symptoms after lumbar spine surgery. MATERIALS AND METHODS: We enrolled 74 patients (59 men and 15 women, mean age 62.9 years) who had undergone lumbar posterior decompression surgery in our department. Mean follow-up after initial lumbar surgery was 26...
January 31, 2018: World Neurosurgery
Keita Uchida, Anatoli N Lopatin
Cardiac t-tubules (TTs) form a network of complex surface membrane invaginations that is essential for proper excitation-contraction coupling. Although electron and optical microscopy studies provided a wealth of important information about the structure of TTs, assessing their functional properties remains a challenge. In this study, we investigated the diffusional accessibility of TTs in intact isolated adult mouse ventricular myocytes using, to our knowledge, a novel fluorescence-based assay. In this approach, a small part of TTs is first locally filled with fluorescent dextran and then its diffusion out of TTs is monitored after rapid removal of extracellular dextran...
January 23, 2018: Biophysical Journal
David N Borg, John O Osborne, Ian B Stewart, Joseph T Costello, Jesse N L Sims, Geoffrey M Minett
OBJECTIVES: This study aimed to determine the reliability of 10 and 20km cycling time trial (TT) performance on the Velotron Pro in recreational cyclists, runners and intermittent-sprint based team sport athletes, with and without a familiarisation. DESIGN: Thirty-one male, recreationally active athletes completed four 10 or 20km cycling TTs on different days. METHODS: During cycling, power output, speed and cadence were recorded at 23Hz, and heart rate and rating of perceived exertion (RPE) were recorded every km...
January 26, 2018: Journal of Science and Medicine in Sport
John Asger Petersen
Clinical deterioration of patients hospitalized on general wards is often preceded by worsening vital signs. If identified early and acted upon quickly, it is conjectured that further deterioration can be prevented. To this means the early warning score (EWS) was implemented in all hospitals in the Capital Region of Denmark in 2013. EWS consists of an aggregated weighted track-and-trigger system (TTS), to identify at-risk patients early, and a treatment protocol to escalate care appropriately and determine the level of competency of the provider...
February 2018: Danish Medical Journal
Ara J Schmitt, Elizabeth McCallum, Renee O Hawkins, Emily Stephenson, Kenneth Vicencio
This study compared the effectiveness of two assistive technologies to accommodate the word reading skills of four middle school students with reading learning disabilities. Kurzweil 3000 is a continuous text-to-speech (TTS) computer software program that allows students to follow along on a computer monitor while passages of text are read aloud. A reading pen is a discontinuous TTS assistive technology device that allows students to scan and hear read aloud words selected by the student. An adapted alternating treatments design was implemented to compare the effects of listening-while-reading using continuous TTS assistive technology, discontinuous TTS assistive technology, and silently reading without accommodation on reading comprehension accuracy and rate...
January 25, 2018: Assistive Technology: the Official Journal of RESNA
Michinori Nariai, Kyongsong Kim, Masaaki Kawauchi, Akihiro Ishii, Misa Kido, Toyohiko Isu, Rinko Kokubo, Daijiro Morimoto, Naotaka Iwamoto, Akio Morita
BACKGROUND: Tarsal tunnel syndrome(TTS)is an entrapment neuropathy of the posterior tibial nerve within the tarsal tunnel below the medial malleolus. An accurate diagnosis is difficult, and TTS is usually diagnosed from clinical symptoms due to the lack of accurate diagnostic tools. We aimed to standardize the diagnosis of TTS using MRI, and report the MRI conditions for clear visualization of the tarsal tunnel. METHODS: We investigated which sequences and MRI conditions would be appropriate for the imaging of the tarsal tunnel in a healthy volunteer...
January 2018: No Shinkei Geka. Neurological Surgery
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