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https://www.readbyqxmd.com/read/28441324/designing-fit-for-purpose-health-and-social-services-for-ageing-populations
#1
Jean Woo
Population ageing is occurring in all countries, regardless of the level of economic development. While the rising burden of chronic diseases and disabilities as a consequence of this demographic transition is well recognized, the increasing prevalence of geriatric syndromes as a public health issue is not as well recognized. Recently the World Health Organization's World Health and Ageing Report emphasized functional ability as an important outcome for aging populations, highlighting the concept of raising intrinsic capacity throughout the life course...
April 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28441061/precisely-where-are-we-going-charting-the-new-terrain-of-precision-prevention
#2
Karen M Meagher, Michelle L McGowan, Richard A Settersten, Jennifer R Fishman, Eric T Juengst
In addition to genetic data, precision medicine research gathers information about three factors that modulate gene expression: lifestyles, environments, and communities. The relevant research tools-epidemiology, environmental assessment, and socioeconomic analysis-are those of public health sciences rather than molecular biology. Because these methods are designed to support inferences and interventions addressing population health, the aspirations of this research are expanding from individualized treatment toward precision prevention in public health...
April 24, 2017: Annual Review of Genomics and Human Genetics
https://www.readbyqxmd.com/read/28440854/neuroprotective-diets-are-associated-with-better-cognitive-function-the-health-and-retirement-study
#3
Claire T McEvoy, Heidi Guyer, Kenneth M Langa, Kristine Yaffe
OBJECTIVES: To evaluate the association between the Mediterranean diet (MedDiet) and the Mediterranean-DASH diet Intervention for Neurodegeneration Delay (MIND diet) and cognition in a nationally representative population of older U.S. adults. DESIGN: Population-based cross-sectional study. SETTING: Health and Retirement Study. PARTICIPANTS: Community-dwelling older adults (N = 5,907; mean age 67.8 ± 10.8). MEASUREMENTS: Adherence to dietary patterns was determined from food frequency questionnaires using criteria determined a priori to generate diet scores for the MedDiet (range 0-55) and MIND diet (range 0-15)...
April 25, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28440800/the-trichodesmium-consortium-conserved-heterotrophic-co-occurrence-and-genomic-signatures-of-potential-interactions
#4
Michael D Lee, Nathan G Walworth, Erin L McParland, Fei-Xue Fu, Tracy J Mincer, Naomi M Levine, David A Hutchins, Eric A Webb
The nitrogen (N)-fixing cyanobacterium Trichodesmium is globally distributed in warm, oligotrophic oceans, where it contributes a substantial proportion of new N and fuels primary production. These photoautotrophs form macroscopic colonies that serve as relatively nutrient-rich substrates that are colonized by many other organisms. The nature of these associations may modulate ocean N and carbon (C) cycling, and can offer insights into marine co-evolutionary mechanisms. Here we integrate multiple omics-based and experimental approaches to investigate Trichodesmium-associated bacterial consortia in both laboratory cultures and natural environmental samples...
April 25, 2017: ISME Journal
https://www.readbyqxmd.com/read/28440782/systematization-of-clinical-trials-related-to-treatment-of-metabolic-syndrome-1980-2015
#5
Santiago Cardona Velásquez, Laura Guzmán Vivares, Jaiberth Antonio Cardona-Arias
INTRODUCTION: Despite the clinical, epidemiological, and economic significance of metabolic syndrome, the profile of clinical trials on this disease is unknown. OBJECTIVE: To characterize the clinical trials related to treatment of metabolic syndrome during the 1980-2015 period. METHODS: Systematic review of the literature using an ex ante search protocol which followed the phases of the guide Preferred Reporting Items for Systematic Reviews and Meta-Analyses in four multidisciplinary databases with seven search strategies...
February 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28440752/assessment-study-of-the-nutritional-status-eating-habits-and-physical-activity-of-the-schooled-population-of-centelles-hostalets-de-baleny%C3%A3-and-sant-mart%C3%A3-de-centelles-alin-2014-study
#6
Queralt Aguilà, Maria Àngels Ramón, Susana Matesanz, Ramon Vilatimó, Irene Del Moral, Carles Brotons, Àngels Ulied
BACKGROUND AND OBJECTIVE: Malnourishment can be caused by either a lack of food or an excess of low-nutrient foods. Due to several factors, this predisposes children to academic failure. The objective of this study is to estimate the prevalence of school children with eating problems, study their nutrition level, food quality in the diet, and level of physical activity. MATERIAL AND METHODS: The study involved the school children between 3 months and 16.5 years of age in the municipalities of Centelles, Hostalets de Balenyà and Sant Martí de Centelles...
March 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28440517/-efficacy-and-future-of-endoscopic-bariatric-surgery-in-the-treatment-of-obesity-and-metabolic-diseases
#7
Shangjia Huang, Junchang Zhang, Zhiyong Dong, Cunchuan Wang
The emerging endoscopic technologies are proved to be effective treatments for obesity in selected patients and to offer the potential advantages of reduced invasiveness, reversibility and repeatability. From the view of operation principle, endoscopic technologies can be classified as restrictive procedure, malabsorption procedure and endoscopic revision of gastric bypass. Restrictive procedures include intragastric balloon, aspiration therapy, endoscopic sleeve gastroplasty (ESG) and transoral gastroplasty...
April 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28440197/hyperprolactinemia-induced-by-antipsychotics-from-diagnosis-to-treatment-approach
#8
Walter Milano, Chiara Colletti, Anna Capasso
Schizophrenia is one of the most severe psychiatric diseases with a significant impact on the psychosocial functioning of the patients. People with schizophrenia are at risk to die prematurely because of their illness with their poor lifestyle contributing to the excess morbidity and higher mortality rate. In particular, lifestyle (e.g. poor diet, low rates of physical activity and increased likelihood to smoke cigarettes) predisposes them to poor physical health and comorbid medical diseases. In addition, the treatment of schizophrenia usually involves the long-term administration of antipsychotic drugs and some of these medications are implicated in the increased risk of metabolic and cardiovascular effects...
April 23, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28440046/attenuated-low-grade-inflammation-following-long-term-dietary-intervention-in-postmenopausal-women-with-obesity
#9
Caroline Blomquist, Malin Alvehus, Jonas Burén, Mats Ryberg, Christel Larsson, Bernt Lindahl, Caroline Mellberg, Ingegerd Söderström, Elin Chorell, Tommy Olsson
OBJECTIVE: Abdominal fat accumulation after menopause is associated with low-grade inflammation and increased risk of metabolic disorders. Effective long-term lifestyle treatment is therefore needed. METHODS: Seventy healthy postmenopausal women (age 60 ± 5.6 years) with BMI 32.5 ± 5.5 were randomized to a Paleolithic-type diet (PD) or a prudent control diet (CD) for 24 months. Blood samples and fat biopsies were collected at baseline, 6 months, and 24 months to analyze inflammation-related parameters...
May 2017: Obesity
https://www.readbyqxmd.com/read/28439675/a-pilot-study-assessing-the-efficacy-of-posterior-tibial-nerve-stimulation-in-the-treatment-of-low-anterior-resection-syndrome
#10
V Vigorita, S Rausei, P Troncoso Pereira, I Trostchansky, A Ruano Poblador, E Moncada Iribarren, C Facal Alvarez, A de San Ildefonso Pereira, E Casal Núñez
BACKGROUND: Low anterior resection for rectal cancer often results in severe bowel dysfunction, specifically low anterior resection syndrome (LARS), with symptoms such as incontinence, urgency, and frequent bowel movements. Percutaneous tibial nerve stimulation (PTNS) resulted in a high rate of success in patients with fecal incontinence. The aim of this study was to evaluate the effectiveness of treatment with PTNS in LARS and to identify predictors of the outcome of the technique. METHODS: The study was conducted from May 2012 to April 2015 at the Alvaro Cunqueiro Hospital, University Hospital Complex of Vigo, Spain...
April 24, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28439518/diabetes-adult-neurogenesis-and-brain-remodeling-new-insights-from-rodent-and-zebrafish-models
#11
REVIEW
Anne-Claire Dorsemans, David Couret, Anaïs Hoarau, Olivier Meilhac, Christian Lefebvre d'Hellencourt, Nicolas Diotel
The prevalence of diabetes rapidly increased during the last decades in association with important changes in lifestyle. Diabetes and hyperglycemia are well-known for inducing deleterious effects on physiologic processes, increasing for instance cardiovascular diseases, nephropathy, retinopathy and foot ulceration. Interestingly, diabetes also impairs brain morphology and functions such as (1) decreased neurogenesis (proliferation, differentiation and cell survival), (2) decreased brain volumes, (3) increased blood-brain barrier leakage, (4) increased cognitive impairments, as well as (5) increased stroke incidence and worse neurologic outcomes following stroke...
2017: Neurogenesis (Austin, Tex.)
https://www.readbyqxmd.com/read/28439501/the-cell-biology-of-the-trichosporon-host-interaction
#12
REVIEW
Cláudio Duarte-Oliveira, Fernando Rodrigues, Samuel M Gonçalves, Gustavo H Goldman, Agostinho Carvalho, Cristina Cunha
Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are an increasing cause of fungal disease among immunocompromised hosts, such as hematological patients and solid organ transplant recipients. The initiation of commensal or pathogenic programs by Trichosporon spp. involves the adaptation to the host microenvironment and its immune system...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28439418/prevention-practices-influencing-frequency-of-occurrence-of-vaso-occlusive-crisis-among-sickle-cell-patients-in-abeokuta-south-local-government-area-of-ogun-state-nigeria
#13
Olorunfemi Emmanuel Amoran, Ahmed Babatunde Jimoh, Omotola Ojo, Temitope Kuponiyi
BACKGROUND: Africa is the most affected continent with 200,000 new born affected by sickle cell anemia annually with of 5% of under five deaths. Nigeria has the largest sickle cell gene pool in the world with about 2% of all babies born to Nigerian parents. This study therefore sets out to assess the prevention practices influencing the frequency of occurrence of vaso-occlusive crisis among patients in Ogun State. METHODS: This study is a descriptive cross-sectional study conducted in Abeokuta South Local Government Area Ogun State...
2017: BMC Hematology
https://www.readbyqxmd.com/read/28439385/effects-of-tailored-health-education-program-on-overweight-elementary-school-students-obesity-related-lifestyle-a-school-based-interventional-study
#14
Sharareh Haghani, Hossein Shahnazi, Akbar Hassanzadeh
OBJECTIVES: Overweight and obesity are regarded as one of the most serious health and nutrition issues worldwide. This is immediately recognizable in both children and adolescents. In this study, we aimed to determine the effects of tailored education on lifestyle modification in elementary school students in Isfahan. METHODS: In a quasi-experimental study, two elementary schools in Isfahan District 3, Iran, were randomly selected to determine the intervention and comparison groups...
March 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28439185/-i-don-t-have-to-explain-people-understand-acceptability-and-cultural-relevance-of-a-mobile-health-lifestyle-intervention-for-filipinos-with-type-2-diabetes
#15
Dale Dagar Maglalang, Grace J Yoo, Rhodora A Ursua, Carissa Villanueva, Catherine A Chesla, Melinda S Bender
BACKGROUND: Filipino Americans have the highest risk for obesity-related type 2 diabetes and related complications compared with all major Asian American subgroups. Identifying effective interventions to improve Filipino health outcomes are needed to reduce this health disparity. OBJECTIVE: To assess the acceptability and cultural relevance of the PilAm Go4Health program - a culturally adapted mobile health weight-loss lifestyle intervention including virtual social networking for Filipino Americans with type 2 diabetes...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/28438892/brain-metabolism-in-health-aging-and%C3%A2-neurodegeneration
#16
REVIEW
Simonetta Camandola, Mark P Mattson
Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing activity in neuronal circuits, and from environmental energetic stressors such as food deprivation and physical exertion. At the cellular level, such adaptive responses include the "strengthening" of existing synapses, the formation of new synapses, and the production of new neurons from stem cells. At the molecular level, bioenergetic challenges result in the activation of transcription factors that induce the expression of proteins that bolster the resistance of neurons to the kinds of metabolic, oxidative, excitotoxic, and proteotoxic stresses involved in the pathogenesis of brain disorders including stroke, and Alzheimer's and Parkinson's diseases...
April 24, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28438269/stone-eating-fungi-mechanisms-in-bioweathering-and-the-potential-role-of-laccases-in-black-slate-degradation-with-the-basidiomycete-schizophyllum-commune
#17
Julia Kirtzel, Daniela Siegel, Katrin Krause, Erika Kothe
Many enzymes, such as laccases, are involved in the saprotrophic lifestyle of fungi and the effects of those may be linked to enhanced bioweathering on stone surfaces. To test this hypothesis, we studied the decomposition of kerogen-enriched lithologies, especially with black slate containing up to 20% of Corg. Indeed, a formation of ditches with attached hyphal material could be observed. To address enzymes involved, proteomics was performed and one group of enzymes, the multicopper oxidase family members of laccases, was specifically investigated...
2017: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/28438268/fungal-biorecovery-of-gold-from-e-waste
#18
Saskia Bindschedler, Thi Quynh Trang Vu Bouquet, Daniel Job, Edith Joseph, Pilar Junier
Waste electric and electronic devices (e-waste) represent a source of valuable raw materials of great interest, and in the case of metals, e-waste might become a prized alternative source. Regarding gold, natural ores are difficult to mine due to their refractory nature and the richest ores have almost all been exploited. Additionally, some gold mining areas are present in geopolitically unstable regions. Finally, the gold mining industry produces toxic compounds, such as cyanides. As a result, the gold present in e-waste represents a nonnegligible resource (urban mining)...
2017: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/28438255/a-strategy-based-on-patient-preference-improves-the-adherence-and-outcomes-of-phosphate-binders-in-hemodialysis%C3%A2
#19
M Dolores Arenas Jiménez, Eduardo Parra Moncasi, Fernando Álvarez-Ude Cotera
PURPOSE: Phosphate binders (PB) have to be taken with food, their interference with an individual's lifestyle and social habits influences treatment adherence. Several PBs are available, and patient preferences should not be ignored when prescribing. The purpose was to know the extent of intentional and unintentional nonadherence to PB in hemodialysis (HD) patients, and to evaluate the long-term results (adherence, serum phosphate levels, and cost) of a strategy of prescription of PB that takes into account patient preferences...
April 25, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28438202/does-parental-and-adolescent-participation-in-an-e-health-lifestyle-modification-intervention-improves-weight-outcomes
#20
Andrew W Tu, Allison W Watts, Jean-Pierre Chanoine, Constadina Panagiotopoulos, Josie Geller, Rollin Brant, Susan I Barr, Louise Mâsse
BACKGROUND: Few studies have evaluated the effect of adherence to a lifestyle intervention on adolescent health outcomes. The objective of this study was to determine whether adolescent and parental adherence to components of an e-health intervention resulted in change in adolescent body mass index (BMI) and waist circumference (WC) z-scores in a sample of overweight/obese adolescents. METHODS: In total, 159 overweight/obese adolescents and their parents participated in an 8-month e-health lifestyle intervention...
April 24, 2017: BMC Public Health
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