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Biomechanical strength

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https://www.readbyqxmd.com/read/29238472/vitamin-e-improved-bone-strength-and-bone-minerals-in-male-rats-given-alcohol
#1
Syuhada Zakaria, Siti-Zulaikha Mat-Husain, Kong Ying-Hwey, Kek Xin-Kai, Abdullah Mohd-Badawi, Nurul-Amiza Abd-Ghani, Muhamad-Arizi Aziz, Norazlina Mohamed
Objectives: Alcohol consumption induces oxidative stress on bone, which in turn increases the risk of osteoporosis. This study determined the effects of vitamin E on bone strength and bone mineral content in alcohol-induced osteoporotic rats. Materials and Methods: Three months old Sprague Dawley male rats were randomly divided into 5 groups: (I) control group; (II) alcohol (3g/kg) + normal saline; (III) alcohol (3g/kg) + olive oil; (IV) alcohol (3g/kg) + alpha-tocopherol (60mg/kg) and (V) alcohol (3g/kg) + palm vitamin E (60mg/kg)...
December 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29238193/in-vivo-evaluation-of-a-novel-nanocomposite-porous-3d-scaffold-in-a-rabbit-model-histological-analysis
#2
Saffanah Khuder Mahmood, Intan-Shameha Abdul Razak, Mustafa Saddam Ghaji, Loqman Mohamed Yusof, Zaid Khudhur Mahmood, Mohd Adha Bin P Rameli, Zuki Abu Bakar Zakaria
The healing of load-bearing segmental defects in long bones is a challenge due to the complex nature of the weight that affects the bone part and due to bending, shearing, axial, and torsional forces. An innovative porous 3D scaffolds implant of CaCO3 aragonite nanocomposite derived from cockle shell was advanced for substitute bone solely for load-bearing cases. The biomechanical characteristics of such materials were designed to withstand cortical bone strength. In promoting bone growth to the implant material, an ideal surface permeability was formed by means of freeze drying and by adding copolymers to the materials...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29229438/pulsed-electromagnetic-fields-pemf-attenuate-changes-in-vertebral-bone-mass-architecture-and-strength-in-ovariectomized-mice
#3
Tao Lei, Zhuowen Liang, Feijiang Li, Chi Tang, Kangning Xie, Pan Wang, Xu Dong, Shuai Shan, Maogang Jiang, Qiaoling Xu, Erping Luo, Guanghao Shen
Pulsed electromagnetic fields (PEMF) has been investigated as a noninvasive alternative method to prevent bone loss for postmenopausal osteoporosis (OP), and the bone tissue involved in these studies are usually long bones such as femur and tibia in OP patients or rat models. However, few studies have investigated the effects of PEMF on the vertebral bone in mice with OP. This study aimed to investigate whether PEMF preserve lumbar vertebral bone mass, microarchitecture and strength in ovariectomized (OVX) mouse model of OP and its associated mechanisms...
December 8, 2017: Bone
https://www.readbyqxmd.com/read/29229272/effect-of-different-resistance-training-protocols-on-the-extracellular-matrix-of-the-calcaneal-tendon-of-rats
#4
Josete Mazon, Andrea Aparecida de Aro, Priscyla Waleska Targino de Azevedo Simões, Edson Rosa Pimentel
The calcaneal tendon extracellular matrix (ECM) is composed of collagen, non-collagenous glycoproteins and proteoglycans, and able to adapt to various biomechanical stimuli. The objective of this study was to analyze the response of different resistance-training protocols, such as hypertrophy, strength and resistance, on the organization of the calcaneal tendon after training. Wistar rats were divided into for groups: untrained (UT), resistance training (RT), hypertrophy training (HT), and strength training (ST)...
December 8, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29228439/beneficial-effects-of-low-level-laser-irradiation-on-senile-osteoporosis-in-rats
#5
C-T Zhu, T Li, P Zhang, M Zou, Q Guo, X-W Qu
OBJECTIVE: To investigate the effect of low-level laser irradiation (LLLI) on bone mineral density (BMD), bone structures, bone biomechanical properties and bone metabolism in senile osteoporosis, and to explore a relatively more secure and effective way to prevent and treat osteoporosis. MATERIALS AND METHODS: Sprague-Dawley (SD) male rats at different age stages (4 months old, 12 months old and 20 months old) were selected and randomly divided into six groups...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29228408/-biomechanical-evaluation-of-rehabilitation-after-surgical-repair-of-achilles-tendon-ruptures
#6
Marlene Mauch, Markus Ulrich, Xaver Kaelin, Bernhard Segesser, Jochen Paul
Background Muscles and tendons are subjected to a high level of stress in everyday life and sports. This often leads to injuries and is associated with training failure and reduced performance as well as with high costs for treatment and rehabilitation. Fast and successful treatment is therefore very important, both from an athletic and economic point of view. This study aims to demonstrate the relevance of biomechanical procedures for the objective monitoring of rehabilitation. At the same time, the results are to be used to establish progress and evaluation criteria for an efficient and controlled rehabilitation...
December 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29227730/physical-and-performance-characteristics-related-to-unintentional-musculoskeletal-injury-in-special-forces-operators-a-prospective-analysis
#7
Nicholas R Heebner, John P Abt, Mita Lovalekar, Kim Beals, Timothy C Sell, Jeffery Morgan, Shawn Kane, Scott Lephart
CONTEXT:   Seventy-seven percent of musculoskeletal injuries sustained by United States Army Special Forces Operators are preventable. Identification of predictive characteristics will promote the development of screening methods to augment injury-prevention programs. OBJECTIVE:   To determine physical and performance characteristics that predict musculoskeletal injuries. SETTING:   Clinical laboratory. PATIENTS OR OTHER PARTICIPANTS:   A total of 95 Operators (age = 32...
December 11, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/29226718/contribution-to-fe-modeling-for-intraoperative-pedicle-screw-strength-prediction
#8
Maxim Van den Abbeele, Jean-Marc Valiadis, Lucas V P C Lima, Pascal Khalifé, Philippe Rouch, Wafa Skalli
Although the use of pedicle screws is considered safe, mechanical issues still often occur. Commonly reported issues are screw loosening, screw bending and screw fracture. The aim of this study was to develop a Finite Element (FE) model for the study of pedicle screw biomechanics and for the prediction of the intraoperative pullout strength. The model includes both a parameterized screw model and a patient-specific vertebra model. Pullout experiments were performed on 30 human cadaveric vertebrae from ten donors...
December 10, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/29225416/getting-peek-to-stick-to-bone-the-development-of-porous-peek-for-interbody-fusion-devices
#9
F Brennan Torstrick, David L Safranski, J Kenneth Burkus, James L Chappuis, Christopher S D Lee, Robert E Guldberg, Ken Gall, Kathryn E Smith
Interbody fusion cages are routinely implanted during spinal fusion procedures to facilitate arthrodesis of a degenerated or unstable vertebral segment. Current cages are most commonly made from polyether-ether-ketone (PEEK) due to its favorable mechanical properties and imaging characteristics. However, the smooth surface of current PEEK cages may limit implant osseointegration and may inhibit successful fusion. We present the development and clinical application of the first commercially available porous PEEK fusion cage (COHERE®, Vertera, Inc...
September 2017: Techniques in Orthopaedics: TIO
https://www.readbyqxmd.com/read/29225150/decellularised-conjunctiva-for-ocular-surface-reconstruction
#10
Joana Witt, Sonja Mertsch, Maria Borrelli, Jana Dietrich, Gerd Geerling, Stefan Schrader, Kristina Spaniol
Conjunctival reconstruction is an integral component of ocular surface restoration. Decellularised tissues are frequently used clinically for tissue engineering. This study identifies porcine decellularised conjunctiva (PDC) and human decellularised conjunctiva (HDC) as promising substitutes for conjunctival reconstruction. PDC and HDC were nearly DNA-free, structurally intact and showed no cytotoxic effects in vitro, which was confirmed by DNA quantification, histology, transmission electron microscopy, collagen quantification and cytotoxicity assay...
December 7, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29222837/low-melt-bioactive-glass-reinforced-3d-printing-akermanite-porous-cages-with-highly-improved-mechanical-properties-for-lumbar-spinal-fusion
#11
Xiurong Ke, Lei Zhang, Xianyan Yang, Juncheng Wang, Chen Zhuang, Zhouwen Jin, An Liu, Tengfei Zhao, Sanzhong Xu, Changyou Gao, Zhongru Gou, Guojing Yang
Although great strides have been made in medical technology, low back/neck pain and intervertebral disc degeneration initiated from disc degenerative disease remains a clinical challenge. Within the field of regenerative medicine therapy, we have sought to improve the biomechanical transformation of spinal fusion procedures conducted using biodegradable porous implants. Specifically, we have focused on developing mechanically strong bioceramic cages for spinal fusion and functional recovery. Herein we fabricated the akermanite (AKE) ceramic-based porous cages using low-melting bioactive glass (BG) and 3D printing technology...
December 9, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29216241/discussion-about-different-cut-off-values-of-conventional-hamstring-to-quadriceps-ratio-used-in-hamstring-injury-prediction-among-professional-male-football-players
#12
Monika Grygorowicz, Martyna Michałowska, Tomasz Walczak, Adam Owen, Jakub Krzysztof Grabski, Andrzej Pyda, Tomasz Piontek, Tomasz Kotwicki
OBJECTIVE: To measure the sensitivity and specificity of differences cut-off values for isokinetic Hcon/Qcon ratio in order to improve the capacity to evaluate (retrospectively) the injury of hamstring muscles in professional soccer screened with knee isokinetic tests. DESIGN: Retrospective study. METHODS: Medical and biomechanical data of professional football players playing for the same team for at least one season between 2010 and 2016 were analysed...
2017: PloS One
https://www.readbyqxmd.com/read/29214889/cell-seeded-adhesive-biomaterial-for-repair-of-annulus-fibrosus-defects-in-intervertebral-discs
#13
Michelle A Cruz, Warren W Hom, Distefano Tyler, Robert Merrill, Olivia M Torre, Huizi A Lin, Andrew Hecht, Svenja Illien-Junger, James C Iatridis
Defects in the annulus fibrosus (AF) of intervertebral discs allow nucleus pulposus tissue to herniate causing painful disability. Microdiscectomy procedures remove herniated tissue fragments but unrepaired defects remain allowing reherniation or progressive degeneration. Cell therapies show promise to enhance repair but methods are undeveloped and carriers are required to prevent cell leakage. To address this challenge, this study developed and evaluated genipin-crosslinked fibrin (FibGen) as an adhesive cell carrier optimized for AF repair that can deliver cells, match AF material properties and have low risk of extrusion during loading...
December 7, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29211969/use-of-platelet-rich-plasma-immediately-after-an-injury-did-not-improve-ligament-healing-and-increasing-platelet-concentrations-was-detrimental-in-an-in-vivo-animal-model
#14
Robert F LaPrade, Laurie R Goodrich, Jennifer Phillips, Grant J Dornan, Travis Lee Turnbull, Michael L Hawes, Kimi D Dahl, Ashley N Coggins, John Kisiday, David Frisbie, Jorge Chahla
BACKGROUND: Limited information in basic science and clinical trials exists to determine if ligament healing may be accelerated with the use of biological adjuvants, such as platelet-rich plasma (PRP). However, there has been widespread acceptance of PRP for use in clinical practice, despite an inadequate understanding of its biological mechanism of action. PURPOSE: To determine whether a single dose of PRP could accelerate ligament healing and correspondingly improve histological characteristics and biomechanical properties when injected immediately postoperatively into the injured medial collateral ligament (MCL) of New Zealand White rabbits...
December 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29199191/an-animal-model-of-reconstruction-of-single-femoral-tunnel-with-single-bone-bi-quadruple-acl-and-internal-fixation
#15
T Gong, X-T Su, Q Xia, J-G Wang
We introduced several variables in an animal model of anterior cruciate ligament (ACL) reconstruction to determine the best parameters for surgery in humans. We divided 130 LYD pigs into two groups depending on whether the femoral tunnel goes through the medial tibial tunnel or through the medial fossa of the knee joint. Each subgroup was further divided. Four weeks after surgery the knee specimens were examined for passive flexion and extension test. No group showed a creep effect. In the biomechanical tests, we recorded maximal strength, maximum load, and stiffness parameters...
December 1, 2017: Journal of Musculoskeletal & Neuronal Interactions
https://www.readbyqxmd.com/read/29198368/trunk-musculoskeletal-response-in-maximum-voluntary-exertions-a-combined-measurement-modeling-investigation
#16
F Ghezelbash, Z El Ouaaid, A Shirazi-Adl, A Plamondon, N Arjmand
Maximum voluntary exertion (MVE) tasks quantify trunk strength and maximal muscle electromyography (EMG) activities with both clinical and biomechanical implications. The aims here are to evaluate the performance of an existing trunk musculoskeletal model, estimate maximum muscle stresses and spinal forces, and explore likely differences between males and females in maximum voluntary exertions. We, therefore, measured trunk strength and EMG activities of 19 healthy right-handed subjects (9 females and 10 males) in flexion, extension, lateral and axial directions...
November 21, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29194186/the-impact-of-different-cross-training-modalities-on-performance-and-injury-related-variables-in-high-school-cross-country-runners
#17
Max R Paquette, Shelby A Peel, Ross E Smith, Mark Temme, Jeffrey N Dwyer
There are many different types of aerobic cross-training modalities currently available. It is important to consider the effects that these different modalities have on running performance and injury risks. The purpose of this study was to compare movement quality, running economy and performance, injury-related biomechanical variables and, hip muscle strength before and after training with different cross-training modalities in high school runners. Thirty-one high school male runners trained for four weeks in one of three cross-training modalities, in addition to a running-only (RUN, n=9) group, for which training sessions replaced two easy runs per week: cycling (CYCLE; n=6), indoor elliptical (ELLIP; n=7) and, outdoor elliptical bike (EBIKE; n=9)...
November 29, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29191201/single-versus-double-row-suture-anchor-fixation-for-greater-tuberosity-fractures-a-biomechanical-study
#18
Gernot Seppel, Tim Saier, Frank Martetschläger, Johannes E Plath, Alberto Guevara-Alvarez, Julia Henschel, Martin Winkler, Peter Augat, Andreas B Imhoff, Stefan Buchmann
BACKGROUND: Fractures of the humeral greater tuberosity (GT) are a frequent injury progressively treated with arthroscopic suture anchor repair. Yet, no biomechanical study has been performed comparing fixation strength of arthroscopic single- (SR) vs. double row (DR) fixation. METHODS: Standardized fractures of the greater tuberosity were created in 12 fresh frozen proximal humeri. After random assignation to the SR or DR group the fixed humeri were tested applying cyclic loading to the supraspinatus and infraspinatus tendon...
December 1, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29184757/biomechanical-assessment-of-new-surgical-method-instead-of-kyphoplasty-to-improve-the-mechanical-behavior-of-the-vertebra-micro-finite-element-study
#19
Seyed Aref Hosseini Faradonbeh, Nima Jamshidi
AIM: To reduce post treatments of kyphoplasty, as a common treatment for osteoporotic vertebrae. METHODS: This study suggests a new method for treating vertebrae by setting the hexagonal porous structure instead of the rigid bone cement mass in the kyphoplasty (KP). The KP procedure was performed on the fresh ovine vertebra of the level L1. Micro finite element modeling was performed based on micro computed tomography of ovine trabecular cube. The hexagonal porous structure was set on one cube instead of the bone cement mass...
November 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29180195/sutures-versus-new-cyanoacrylates-in-prosthetic-abdominal-wall-repair-a-preclinical-long-term-study
#20
Gemma Pascual, Marta Rodríguez, Claudia Mesa-Ciller, Bárbara Pérez-Köhler, Mar Fernández-Gutiérrez, Julio San Román, Juan M Bellón
BACKGROUND: As an alternative to sutures, meshes used for hernia repair can be fixed using cyanoacrylate-based adhesives. Attempts to improve these adhesives include alkyl-chain lengthening to reduce their toxicity. This preclinical study compares the long-term behavior of cyanoacrylates of different chain lengths already used in hernia repair and new ones for this application. MATERIALS AND METHODS: Partial abdominal wall defects were repaired using a Surgipro mesh in 18 New Zealand White rabbits, and groups were established according to the mesh fixation method: sutures (control), Glubran 2 (n-butyl), Ifabond (n-hexyl), and the new adhesives SafetySeal (n-butyl), and Evobond (n-octyl)...
December 2017: Journal of Surgical Research
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