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https://www.readbyqxmd.com/read/29754480/pycnogenol%C3%A2-supplementation-in-minimal-cognitive-dysfunction
#1
Morio Hosoi, Gianni Belcaro, Aristide Saggino, Roberta Luzzi, Mark Dugall, Beatrice Feragalli
BACKGROUND: Impairments in cognitive function are difficult to evaluate and measure. In most cases, subjects do not perceive any alteration in their own status, particularly in case of mild cognitive impairment. In case of minimal alterations of cognitive function, no real treatment exists at the moment. Functional and/or temporary alterations in the cerebral microcirculation may be involved in cognitive impairment, and some aspects of MCI may be theoretically caused by perfusional problems...
June 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29684771/coenzyme-q-10-supplementation-reduces-oxidative-stress-and-decreases-antioxidant-enzyme-activity-in-children-with-autism-spectrum-disorders
#2
Elham Mousavinejad, Mohammad Ali Ghaffari, Forough Riahi, Maryam Hajmohammadi, Zeinab Tiznobeyk, Masoumeh Mousavinejad
Antioxidants and oxidative stress can participate in pathobiochemical mechanisms of autism spectrum disorders (ASDs). The aim was to identify the effects of early CoQ10 supplementation on oxidative stress in children with ASDs. Ninety children with ASDs were included in this study, based on DSM-IV criteria and using Childhood Autism Rating Scale (CARS) scores. Concentrations of CoQ10 , MDA, total antioxidant status (TAS) assay, and antioxidant enzymes (superoxide dismutase or SOD and glutathione peroxidase or GPx) activity were determined in serum before and after 100 days of supportive therapy with CoQ10 at daily doses of 30 and 60 mg...
April 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29651640/characteristics-of-new-onset-and-chronic-sleep-medication-users-among-older-adults-a-retrospective-study-of-a-us-medigap-plan-population-using-propensity-score-matching
#3
Shirley Musich, Shaohung S Wang, Luke B Slindee, Lynn Saphire, Ellen Wicker
BACKGROUND: Prescription sleep medications are often utilized to manage sleep problems among older adults even though these drugs are associated with multiple risks. OBJECTIVE: The aim was to determine the prevalence and characteristics of new-onset compared to chronic sleep medication users and to examine factors associated with the conversion from new to chronic use. A secondary objective was to investigate the impact of sleep medications on health outcomes of injurious falls and patterns of healthcare utilization and expenditures...
April 12, 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29530374/factors-associated-with-insomnia-and-complementary-medicine-use-in-children-results-of-a-national-survey
#4
Ezra M Cohen, Michelle L Dossett, Darshan H Mehta, Roger B Davis, Yvonne C Lee
OBJECTIVES: Sleep difficulties are a serious health problem in children, and interest in using complementary and alternative medicine (CAM) therapies to treat sleep is growing. In this study, we aimed to identify: the prevalence of sleep difficulties in children, and the prevalence and patterns of CAM use among children with trouble sleeping. METHODS: We used the 2012 National Health Interview Survey (NHIS) dataset to estimate the prevalence of sleep difficulties and CAM use in children ages 6-17 years...
April 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29473880/assessment-and-treatment-of-pediatric-sleep-problems-knowledge-skills-attitudes-and-practices-in-a-group-of-community-child-psychiatrists
#5
Ali Anwar, Michael D Yingling, Alicia Zhang, Ujjwal Ramtekkar, Ginger E Nicol
As part of a university-based quality improvement project, we aimed to evaluate child psychiatrists' knowledge, skills, attitudes, and practices regarding assessment and treatment of pediatric sleep problems. We developed a nine-question survey of knowledge, skills, attitudes, and practices regarding assessing for and treating sleep complaints in pediatric patients, and administered this survey to child psychiatrists in training and in practice in the state of Missouri. Respondents reported sleep hygiene as the first-line treatment strategy, followed by the use of supplements or over-the-counter remedies...
February 23, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29338780/coping-with-dry-eyes-a-qualitative-approach
#6
Sharon Yeo, Louis Tong
BACKGROUND: Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS: Six focus group sessions were conducted at the Singapore National Eye Centre (SNEC), premises of an eye research institute. These focus groups consist of a spectrum of dry eye sufferers (30 women, 8 men, aged 61 ± 11...
January 16, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/28969341/caffeine-to-optimize-cognitive-function-for-military-mission-readiness-a-systematic-review-and-recommendations-for-the-field
#7
REVIEW
Cindy Crawford, Lynn Teo, Lynn Lafferty, Angela Drake, John J Bingham, Matthew D Gallon, Meghan L O'Connell, Holly K Chittum, Sonya M Arzola, Kevin Berry
Context: In 2001 the Institute of Medicine (IOM) released a report on the use of caffeine during sustained military operations in which recommendations for research and practice were made. Objective: This systematic review serves as an update on the current quality of the evidence and addresses gaps in the current literature surrounding the effects of caffeinated foods and beverages on cognitive functioning in healthy adult populations exposed to military-like moderators...
June 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28954536/gastrointestinal-dysfunctions-as-a-risk-factor-for-sleep-disorders-in-children-with-idiopathic-autism-spectrum-disorder-a-retrospective-cohort-study
#8
Lena M McCue, Louise H Flick, Kimberly A Twyman, Hong Xian
Sleep disorders often co-occur with autism spectrum disorder. They further exacerbate autism spectrum disorder symptoms and interfere with children's and parental quality of life. This study examines whether gastrointestinal dysfunctions increase the odds of having sleep disorders in 610 children with idiopathic autism spectrum disorder, aged 2-18 years, from the Autism Genetic Resource Exchange research program. The adjusted odds ratio for sleep disorder among those with gastrointestinal dysfunctions compared to those without was 1...
November 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28941378/associations-among-adolescent-sleep-problems-emotion-regulation-and-affective-disorders-findings-from-a-nationally-representative-sample
#9
Cara A Palmer, Benjamin Oosterhoff, Joanne L Bower, Julie B Kaplow, Candice A Alfano
Sleep problems in youth reliably forecast the development of anxiety and mood disorders, presumably due to increased emotional difficulties. However, precise emotional mechanisms have yet to be delineated. The current study investigated how sleep problems in adolescence are associated with different emotion regulation strategies, and how sleep and psychiatric risk may be indirectly associated via poor emotion regulation. This study utilized data from the National Comorbidity Survey-Adolescent Supplement, a nationally representative sample from the United States (N = 10,148; age range 13-18 years)...
September 18, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28835328/positional-skull-deformities
#10
Christian Linz, Felix Kunz, Hartmut Böhm, Tilmann Schweitzer
BACKGROUND: Especially in the first 6 months of life, skull deformities manifesting as a uni- or bilateral flattening of the occiput often give rise to questions of differential diagnosis and potential treatment. In this review, the authors summarize the current understanding of risk factors for this condition, and the current state of the relevant diagnostic assessment and options for treatment. METHODS: The recommendations given in this selective review of the literature are based on current studies and on existing guidelines on the prevention of sudden infant death, the recommendations of the German Society for Pediatric Neurology (Deutsche Gesellschaft für Neuropädiatrie), and the American guidelines on the treatment of positional plagiocephaly in infancy...
August 7, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28639298/prevalence-patterns-and-factors-associated-with-psychotropic-use-in-older-adults-with-intellectual-disabilities-in-ireland
#11
M O'Dwyer, J Peklar, N Mulryan, P McCallion, M McCarron, M C Henman
BACKGROUND: People with intellectual disability (ID) are at increased risk of exposure to psychotropic drugs and psychotropic polypharmacy because of the higher prevalence of mental health conditions present and more controversially, the use of these agents to treat challenging behaviours. Despite the fact that many adults with ID are exposed to psychotropic polypharmacy, few studies to date have focused on the patterns of use of multiple psychotropics, or factors associated with psychotropic polypharmacy, particularly in the older population...
June 21, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28524102/sleep-promoting-effects-and-possible-mechanisms-of-action-associated-with-a-standardized-rice-bran-supplement
#12
Hyejin Yang, Minseok Yoon, Min Young Um, Jaekwang Lee, Jonghoon Jung, Changho Lee, Yun-Tai Kim, Sangoh Kwon, Boknam Kim, Suengmok Cho
Natural sleep aids are becoming more popular due to the widespread occurrence of sleep disorders. The objective of this study was to assess the sleep-promoting effects of rice bran-a product that is considered as a functional ingredient. To evaluate the sleep-promoting effects of a standardized rice bran supplement (RBS), we employed a pentobarbital-induced sleep test and conducted analyses of sleep architecture. In addition, the effect of RBS on a caffeine-induced sleep disturbance was investigated. Oral administration of RBS (500 and 1000 mg/kg) produced a significant decrease in sleep latency and increase in sleep duration in pentobarbital-induced sleep in mice...
May 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28452602/effect-of-enzogenol%C3%A2-supplementation-on-cognitive-executive-and-vestibular-balance-functioning-in-chronic-phase-of-concussion
#13
A Walter, K Finelli, X Bai, P Arnett, T Bream, P Seidenberg, S Lynch, B Johnson, S Slobounov
This study examined the feasibility of Enzogenol® as a potential treatment modality for concussed individuals with residual symptoms in the chronic phase. Forty-two student-athletes with history of sport-related concussion were enrolled, comparing Enzogenol® versus placebo. Testing was conducted using virtual reality (VR) and electroencephalography (EEG), with neuropsychological (NP) tasks primarily used to induce cognitive challenges. After six weeks, the Enzogenol® group showed enhanced frontal-midline theta, and decreased parietal theta power, indicating reduced mental fatigue...
2017: Developmental Neuropsychology
https://www.readbyqxmd.com/read/28422269/wake-and-light-therapy-for-moderate-to-severe-depression-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
M Kragh, K Martiny, P Videbech, D N Møller, C S Wihlborg, T Lindhardt, E R Larsen
OBJECTIVE: To examine the efficacy of using wake and light therapy as a supplement to standard treatment of hospitalized patients with depression. METHOD: In this randomized, controlled study, 64 patients with moderate-to-severe depression were allocated to standard treatment or to the intervention, which additionally consisted of three wake therapy sessions in one week, 30-min daily light treatment and sleep time stabilization over the entire nine-week study period...
December 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28258648/effectiveness-of-sleep-based-interventions-for-children-with-autism-spectrum-disorder-a-meta-synthesis
#15
REVIEW
Belinda M Cuomo, Sharmila Vaz, Elinda Ai Lim Lee, Craig Thompson, Jessica M Rogerson, Torbjorn Falkmer
Sleep problems are common in children with autism spectrum disorder (ASD). This meta-synthesis collated eight previously published systematic reviews examining the efficacy of sleep interventions in children with ASD in an attempt to present a clear analysis of trialed interventions. The collated reviews consider five major groups of sleep interventions for children with ASD: melatonin therapy, pharmacologic treatments other than melatonin, behavioral interventions, parent education/education programs, and alternative therapies (massage therapy, aromatherapy, and multivitamin and iron supplementation)...
May 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28041599/influence-of-equol-and-resveratrol-supplementation-on-health-related-quality-of-life-in-menopausal-women-a-randomized-placebo-controlled-study
#16
RANDOMIZED CONTROLLED TRIAL
Sergio Davinelli, Giovanni Scapagnini, Fulvio Marzatico, Vincenzo Nobile, Nicola Ferrara, Graziamaria Corbi
OBJECTIVE: This study was designed to evaluate the effects of equol and resveratrol supplementation on health-related quality of life (HRQoL) in otherwise healthy menopausal women with hot flashes, anxiety and depressive symptoms. METHODS: Sixty recently menopausal women aged 50-55 years were randomized in a 12-week, placebo-controlled trial to receive 200mg of fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day). The primary outcome was the change in score on the Menopause Rating Scale (MRS), used to evaluate the severity of age-/menopause-related complaints...
February 2017: Maturitas
https://www.readbyqxmd.com/read/27861433/understanding-phenotypes-of-obstructive-sleep-apnea-applications-in-anesthesia-surgery-and-perioperative-medicine
#17
REVIEW
Yamini Subramani, Mandeep Singh, Jean Wong, Clete A Kushida, Atul Malhotra, Frances Chung
Obstructive sleep apnea (OSA) is a prevalent sleep-disordered breathing with potential long-term major neurocognitive and cardiovascular sequelae. The pathophysiology of OSA varies between individuals and is composed of different underlying mechanisms. Several components including the upper airway anatomy, effectiveness of the upper airway dilator muscles such as the genioglossus, arousal threshold of the individual, and inherent stability of the respiratory control system determine the pathogenesis of OSA...
January 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27668002/the-effects-of-nutritional-juice-supplementation-on-the-extent-of-climacteric-symptoms-an-observational-study
#18
Stefanie I Siebler, Ursula Gresser, Barbara M Richartz
Objective. This study aims to evaluate the effect of daily dietary nutritional supplement on somatic, psychological, and urogenital symptoms in postmenopausal women. Material and Methods. In this study 28 healthy, symptomatic, peri- and postmenopausal women of 47-67 years of age were allocated to use the nutritional supplement JuicePLUS+®. Primary research parameters: Menopause Rating Scale (MRS) was used to assess menopausal symptoms at baseline and after 8 and 16 weeks of treatment. Secondary parameters: proliferation behaviour of vaginal smear was scored at baseline and after treatment...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27605136/quality-of-life-priorities-in-patients-with-thyroid-cancer-a-multinational-european-organisation-for-research-and-treatment-of-cancer-phase-i-study
#19
MULTICENTER STUDY
Susanne Singer, Olga Husson, Iwona M Tomaszewska, Laura D Locati, Naomi Kiyota, Ulrike Scheidemann-Wesp, Dirk Hofmeister, Melanie Winterbotham, Christine Brannan, Cláudia Araújo, Eva M Gamper, Dagmara Kulis, Harald Rimmele, Guy Andry, Lisa Licitra
BACKGROUND: The objectives of this study were to determine quality of life (QoL) issues that are relevant to thyroid cancer patients cross-culturally, and to identify those with highest relevance to them in addition to the more general issues covered by the core European Organisation for Research and Treatment of Cancer QoL questionnaire (EORTC QLQ-C30). METHODS: A systematic literature search provided a list of potentially relevant QoL issues to supplement the core questionnaire EORTC QLQ-C30, which is widely used in research and in care and addresses QoL issues relevant to all groups of cancer patients...
November 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27580590/sleep-patterns-among-shift-working-flight-controllers-of-the-international-space-station-an-observational-study-on-the-jaxa-flight-control-team
#20
Koh Mizuno, Akiko Matsumoto, Tatsuya Aiba, Takashi Abe, Hiroshi Ohshima, Masaya Takahashi, Yuichi Inoue
BACKGROUND: Flight controllers of the International Space Station (ISS) are engaged in shift work to provide 24-h coverage to support ISS systems. The purpose of this study was to investigate the prevalence and associated factors of shift work sleep disorder (SWSD) among Japanese ISS flight controllers. METHODS: A questionnaire study was conducted using the Standard Shiftwork Index to evaluate sleep-related problems and possible associated variables. Among 52 respondents out of 73 flight controllers, 30 subjects were identified as night shift workers who worked 3 or more night shifts per month...
September 1, 2016: Journal of Physiological Anthropology
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