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https://www.readbyqxmd.com/read/29454898/dietary-values-of-forsythia-suspensa-extract-in-penaeus-monodon-under-normal-rearing-and-vibrio-parahaemolyticus-3hp-vp-3hp-challenge-conditions-effect-on-growth-intestinal-barrier-function-immune-response-and-immune-related-gene-expression
#1
Jia-Jun Xie, Xu Chen, Tian-Yu Guo, Shi-Wei Xie, Hao-Hang Fang, Zhen-Lu Liu, Yan-Mei Zhang, Li-Xia Tian, Yong-Jian Liu, Jin Niu
Two trials were conducted to determine the effects of dietary Forsythia suspensa extract (FSE) on shrimp, Penaeus monodon, first on growth performance, second on the immune response and immune related gene expression of shrimp. In trial 1, shrimp (mean initial wet weight about 3.02 g) were fed with five diets containing 0% (basal diet), 0.01%, 0.02%, 0.04% and 0.06% FSE in triplicate for 60 days. Growth performance (final body wet weight, FBW; weight gain, WG; biomass gain, BG) of shrimp fed FSE diets were higher (P < 0...
February 15, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29451831/high-dose-perinatal-folic-acid-supplementation-alters-insulin-sensitivity-in-sprague-dawley-rats-and-diminishes-the-expression-of-adiponectin
#2
Ayodele Olufemi Morakinyo, Titilola Aderonke Samuel, Funmileyi Olubajo Awobajo, Gabriel Olorunleke Oludare, Adekunle Mofolorunso
The possible intake of folate in excess of the recommended upper levels is a matter of critical importance. This study was conducted to investigate the effects of prenatal and postnatal high folic acid supplementation (FAS) on glucose tolerance, insulin sensitivity, lipid metabolism, and expression of adiponectin in rats. The study included 20 female rats divided into two groups: control group and FAS group (receiving high folic acid supplemented diet). Both groups of female rats were mated and pregnancy confirmed...
February 16, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29445271/immune-cell-response-to-strenuous-resistive-breathing-comparison-with-whole-body-exercise-and-the-effects-of-antioxidants
#3
Andreas Asimakos, Dimitrios Toumpanakis, Maria-Helena Karatza, Spyridoula Vasileiou, Paraskevi Katsaounou, Zafeiria Mastora, Theodoros Vassilakopoulos
Background/hypothesis: Whole body exercise (WBE) changes lymphocyte subset percentages in peripheral blood. Resistive breathing, a hallmark of diseases of airway obstruction, is a form of exercise for the inspiratory muscles. Strenuous muscle contractions induce oxidative stress that may mediate immune alterations following exercise. We hypothesized that inspiratory resistive breathing (IRB) alters peripheral blood lymphocyte subsets and that oxidative stress mediates lymphocyte subpopulation alterations following both WBE and IRB...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29442544/pyridoxine-add-on-treatment-for-the-control-of-behavioral-adverse-effects-induced-by-levetiracetam-in-children-a-case-control-prospective-study
#4
Marino Silvia, Vitaliti Giovanna, Marino Simona Domenica, Pavone Piero, Provvidenti Simona, Romano Catia, Falsaperla Raffaele
BACKGROUND: Few studies on adult and pediatric patients have shown pyridoxine efficacy as additional therapy for those receiving levetiracetam (LEV) to prevent and mitigate behavioral adverse effects (BAEs). OBJECTIVE: The aim of our study was to analyze the safety and efficacy of pyridoxine supplementation in the prevention of LEV adverse effects, including suicidal ideation. METHODS: This randomized, case-control trial included patients receiving LEV as monotherapy treatment...
February 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29442353/the-effect-of-vitamin-d-supplementation-on-sexual-functioning-and-depressive-symptoms-in-young-women-with-low-vitamin-d-status
#5
Robert Krysiak, Anna Szwajkosz, Bogdan Marek, Bogusław Okopień
BACKGROUND: Hypovitaminosis D is associated with abnormal female sexual functioning. The aim of our study was to assess whether vitamin D supplementation affects sexual functioning and depressive symptoms in young women with low vitamin D status. METHODS: The study included 47 women with vitamin D deficiency or insufficiency. All women with vitamin D deficiency were treated with oral vitamin D, while women with vitamin D insufficiency were either treated with vitamin D or left untreated...
February 14, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29432893/improvement-of-cognitive-functions-in-response-to-a-regular-nordic-walking-training-in-elderly-women-a-change-dependent-on-the-training-experience
#6
A Gmiąt, J Jaworska, K Micielska, J Kortas, K Prusik, K Prusik, M Lipowski, A Radulska, N Szupryczyńska, J Antosiewicz, E Ziemann
Although regular physical activity is known to benefit health of aging populations, there are still many factors, which regulate exercise-induced adaptive changes. Among many vitamin D and myokines are under consideration. We, therefore, evaluated the influence of a single session of and regular Nordic Walking (NW) training combined with vitamin D supplementation on cognitive functions and muscle strength and some elements of the amino-acid profile. Thirty-five healthy elderly women (68 ± 5 years old) from health promotion programmes took part in the study...
February 9, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29432877/the-effects-of-vitamin-d-and-probiotic-co-supplementation-on-mental-health-parameters-and-metabolic-status-in-type-2-diabetic-patients-with-coronary-heart-disease-a-randomized-double-blind-placebo-controlled-trial
#7
Fariba Raygan, Vahidreza Ostadmohammadi, Fereshteh Bahmani, Zatollah Asemi
BACKGROUND: This study was carried out to evaluate the effects of vitamin D and probiotic co-supplementation on mental health parameters and metabolic status in diabetic people with coronary heart disease (CHD). METHODS: This randomized, double-blind, placebo-controlled trial was carried out among 60 diabetic people with CHD, aged 45-85 years old. Subjects were randomly allocated into two groups to receive either 50,000 IU vitamin D every 2 weeks plus 8 × 10 9 CFU/g probiotic of Lactocare Zisttakhmir Co (n = 30) or placebo (n = 30) for 12 weeks...
February 9, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29432228/growth-and-pubertal-development-in-hiv-infected-adolescents
#8
Paige L Williams, Julie Jesson
PURPOSE OF REVIEW: We present an overview of recent research in the inter-related areas of growth and pubertal development among adolescents with HIV. Growth deficits early in childhood can lead to delayed puberty, with subsequent effects on pubertal growth spurts and bone health. RECENT FINDINGS: Impaired growth remains a critical concern, particularly in low-resource settings, where stunting, wasting and underweight remain pervasive. Antiretroviral treatment (ART) initiation results in improved growth, with greatest growth recovery in the first years and more improvement in weight than in height...
February 9, 2018: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29430661/glucose-and-lactate-as-metabolic-constraints-on-presynaptic-transmission-at-an-excitatory-synapse
#9
Sarah J Lucas, Christophe B Michel, Vincenzo Marra, Joshua L Smalley, Matthias H Hennig, Bruce P Graham, Ian D Forsythe
The synapse has high energy demands, which increase during intense activity. Presynaptic ATP production depends on substrate availability and usage will increase during activity, which in turn could influence transmitter release and information transmission. We investigated transmitter release at the mouse calyx of Held synapse using glucose or lactate (10, 1 or 0 mm) as the extracellular substrates while inducing metabolic stress. High frequency stimulation (HFS) and recovery paradigms evoked trains of EPSCs monitored under voltage-clamp...
February 12, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29429821/obstructive-sleep-apnea-screening-among-surgical-patients-a-quality-improvement-project
#10
Linda Lakdawala, Bryce Dickey, Mohammad Alrawashdeh
PURPOSE: Obstructive sleep apnea (OSA) increases the risk of respiratory depression in surgical patients. This project screened patients for OSA and explored its relationship with respiratory complications. DESIGN: Quality improvement project. METHODS: Neurosurgical patients were preoperatively screened using STOP-Bang questionnaire scores of 5 or greater as high risk and less than 5 as low risk for moderate-to-severe OSA. Postoperative respiratory complications were compared between both OSA groups...
February 8, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29426793/-widowhood-loneliness-and-health-in-old-age
#11
Juan López Doblas, María Del Pilar Díaz Conde
INTRODUCTION: Elderly people are one of the most vulnerable groups in the population as regards loneliness, especially among those living alone. This paper aims to assess the impact of the feeling of loneliness on the elderly, taking into account that the loss of a spouse is the main reason that triggers this feeling. MATERIAL AND METHODS: Findings are presented from a qualitative study conducted in Spain. Data were gathered using a focus group approach (8 focus groups, differentiated by gender and place of residence)...
February 6, 2018: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29420166/curcumin-mediated-regulation-of-intestinal-barrier-function-the-mechanism-underlying-its-beneficial-effects
#12
Siddhartha S Ghosh, Hongliang He, Jing Wang, Todd W Gehr, Shobha Ghosh
Curcumin has anti-inflammatory, anti-oxidant and anti-proliferative properties established largely by in vitro studies. Accordingly, oral administration of curcumin beneficially modulates many diseases including diabetes, fatty-liver disease, atherosclerosis, arthritis, cancer and neurological disorders such as depression, Alzheimer's or Parkinson's disease. However, limited bioavailability and inability to detect curcumin in circulation or target tissues has hindered the validation of a causal role. We established curcumin-mediated decrease in the release of gut bacteria-derived lipopolysaccharide (LPS) into circulation by maintaining the integrity of the intestinal barrier function as the mechanism underlying the attenuation of metabolic diseases (diabetes, atherosclerosis, kidney disease) by curcumin supplementation precluding the need for curcumin absorption...
January 8, 2018: Tissue Barriers
https://www.readbyqxmd.com/read/29416322/quality-of-life-and-psychological-consequences-in-elderly-patients-after-a-hip-fracture-a-review
#13
REVIEW
Konstantinos I Alexiou, Andreas Roushias, Sokratis E Varitimidis, Konstantinos N Malizos
Fractures due to fragility of the bone around the hip joint have become a major public health issue, presenting with an increasing incidence due to the growth of the elderly population. The purpose of this review was to evaluate the impact of hip fractures on the quality of life (QoL), health status (HS), functioning, and psychological parameters, and factors influencing the outcome and the appropriate interventions for improvement of elderly patients. A systematic electronic search of the relevant literature was carried out using the CINAHL, Cochrane, EMBASE, Medline (OvidSP), and PubMed databases spanning the time period from their establishment up to January 2017...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29415875/psychosocial-distress-of-patients-with-psoriasis-protocol-for-an-assessment-of-care-needs-and-the-development-of-a-supportive-intervention
#14
Jördis Maria Zill, Jörg Dirmaier, Matthias Augustin, Sarah Dwinger, Eva Christalle, Martin Härter, Ulrich Mrowietz
BACKGROUND: Psoriasis is a chronic inflammatory disease that is often associated with a number of somatic and mental comorbidity. Patients with psoriasis show an increased risk of depression and (social) anxiety. OBJECTIVE: The aims of this study are 1) to explore the psychosocial distress of patients with psoriasis and to assess their care needs; and 2) to develop a supportive intervention based on the prior results. METHODS: A multi-stage design with four phases combining quantitative and qualitative methodology will be used and conducted in two centers...
February 7, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29397672/depression-and-mania-induce-pro-inflammatory-activation-of-macrophages-following-application-of-serum-from-individuals-with-bipolar-disorder
#15
Pamela Ferrari, Mariana Migliorini Parisi, Rafael Colombo, Matheus Becker, Gabriel Fries, Bruna Maria Ascoli, Luiza Paul Géa, Márcia Kauer-Sant Anna, Flávio Kapczinski, Fábio Klamt, Fátima T C R Guma, Adriane Ribeiro Rosa, Florencia M Barbé-Tuana
Objective: Evidence has suggested that immune imbalance is involved with bipolar disorder (BD); however, its precise mechanism is poorly understood. This study investigated whether biochemical changes in the serum from BD patients could modulate the phenotype of cultured macrophages. Methods: Eighteen subjects with BD and five healthy individuals were included in this study. The human monocyte cell line U-937 was activated with phorbol 12-myristate 13-acetate (PMA) and polarization was induced with RPMI-1640 media supplemented with 10% serum from each patient for 24 hours...
February 28, 2018: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29396798/the-involvement-of-cytochrome-c-oxidase-in-mitochondrial-fusion-in-primary-cultures-of-neonatal-rat-cardiomyocytes
#16
Wen Yin, Rui Li, Xiaorong Feng, Y James Kang
Cytochrome c oxidase (CCO) is a copper-dependent enzyme of mitochondrial respiratory chain. In pressure overload-induced cardiac hypertrophy, copper level and CCO activity are both depressed, along with disturbance in mitochondrial fusion and fission dynamics. Copper repletion leads to recovery of CCO activity and normalized mitochondrial dynamics. The present study was undertaken to define the link between CCO activity and mitochondrial dynamic changes. Primary cultures of neonatal rat cardiomyocytes were treated with phenylephrine to induce cell hypertrophy...
February 2, 2018: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/29393662/postpartum-depression-and-vitamin-d-a-systematic-review
#17
Shirin Amini, Sima Jafarirad, Reza Amani
Postpartum depression (PPD) is a prevalent mood disorder estimated to affect 20%-40% of women worldwide after childbirth. In recent studies, the effect of vitamin D on prevention of mood disorders and depression has been investigated, but it is still unclear how vitamin D may affect PPD. The evidence on the relevance between vitamin D deficiency and PPD is inconsistent, and assessment of the recent literature has not previously been carried out. Moreover, there are few clinical studies on PPD and vitamin D supplementation...
February 2, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29390199/intramuscular-testosterone-supplementation-ameliorates-depression-in-hypogonadal-men-a-retrospective-study-in-an-outpatient-department
#18
A Miclea, M Miclea, M Pistor, K Stegmayer, R Hoepner
INTRODUCTION: Substantial evidence has indicated an association between hypogonadism and depressive symptoms, which led to the conduction of studies that found an ameliorating effect of testosterone (T) supplementation (S) upon depression in men. METHODS: Retrospective analysis of medical records identified 16 depressed, hypogonadal men who have not responded adequately to initial antidepressant therapy and subsequently received intramuscular T injections. Following the proposal of Button et al...
February 1, 2018: Pharmacopsychiatry
https://www.readbyqxmd.com/read/29385721/database-analysis-of-depression-and-anxiety-in-a-community-sample-response-to-a-micronutrient-intervention
#19
Samantha M Kimball, Naghmeh Mirhosseini, Julia Rucklidge
BACKGROUND: Depression and anxiety are common mental health concerns worldwide. Broad-spectrum multi-vitamin/mineral approaches have been found to alleviate a number of psychiatric symptoms. We investigated the effects of a nutrient intervention program, which includes optimizing vitamin D levels, on depression and anxiety outcomes from community-based program. METHODS: We evaluated self-reported health measures of depression and anxiety collected as part of a community-based program focused on optimizing overall health through nutritional supplementation, education and lifestyle advice...
January 30, 2018: Nutrients
https://www.readbyqxmd.com/read/29381896/effects-of-dietary-spermine-supplementation-on-cell-cycle-apoptosis-and-amino-acid-transporters-of-the-thymus-and-spleen-in-piglets
#20
Wei Cao, Xianjian Wu, Gang Jia, Hua Zhao, Xiaoling Chen, Caimei Wu, Jingyi Cai, Jing Wang, Guangmang Liu
Objective: This study investigated whether spermine supplementation could regulate cell cycle, apoptosis, and amino acid transporter-related genes expression in the thymus and spleen of early weaned piglets. Methods: Eighty female piglets were randomly distributed to receive adequate nutrients supplemented with spermine (0.4 mmol kg-1 body weight 24h-1) or to be provided with restricted nourishment supplemented with normal saline for 7 h or 3, 6, or 9 d in pairs...
January 26, 2018: Asian-Australasian Journal of Animal Sciences
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