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Cervical cancer review

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https://www.readbyqxmd.com/read/28918994/meaningful-methods-for-increasing-human-papillomavirus-vaccination-rates-an%C3%A2-integrative-literature-review
#1
Kristin Vollrath, Susan Thul, Jenny Holcombe
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States and is a well-known cause of oropharyngeal, cervical, vaginal, vulvar, penile, and anal cancers. Despite the proven efficacy of the HPV vaccine, vaccination rates remain persistently low. Much literature has focused on attitudes toward the HPV vaccine; however, researchers have also investigated strategies clinicians can use to improve vaccination attitudes and acceptance. Such strategies include provider education, vaccine reminder/recall, and chart audit and feedback...
September 14, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28918099/role-of-hpv-dna-testing-in-modern-gynaecological-practice
#2
REVIEW
Guglielmo Ronco, Paolo Giorgi Rossi
The identification of some types of human papillomavirus (HPV) as necessary, but not sufficient, cause of cervical cancer has suggested the use of HPV testing in cervical cancer prevention. A large number of studies has provided evidence supporting its application (1) as primary screening test, (2) for triaging borderline cytology, (3) for follow-up after positive primary test but no abnormal histology and (4) as a test of cure. They also allowed a reasonably good definition of the appropriate policies and protocols, leading to the delivery of evidence-based guidelines resulting from a systematic review of the literature...
August 12, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28915656/patterns-and-clinical-significance-of-cervical-lymph-node-metastasis-in-papillary-thyroid-cancer-patients-with-delphian-lymph-node-metastasis
#3
Guibin Zheng, Hua Zhang, Shaolong Hao, Chengxin Liu, Jie Xu, Jinyao Ning, Guochang Wu, Lixin Jiang, Guojun Li, Haitao Zheng, Xicheng Song
Although the roles of Delphian lymph node (DLN) metastasis in papillary thyroid cancer (PTC) have been previously reported, there are still limited data on correlations of clinicopathologic factors with DLN metastasis and unique patterns of cervical node subsite metastasis in PTC patients with DLN metastasis. We retrospectively reviewed medical records of 320 patients with a diagnosis of PTC who underwent primary surgery. Clinicopathologic features and DLN metastasis patterns were analyzed for predicting extensive cervical lymph node metastasis...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28905520/vaginal-enterobius-vermicularis-diagnosed-on-liquid-based-cytology-during-papanicolaou-test-cervical-cancer-screening-a-report-of-two-cases-and-a-review-of-the-literature
#4
Chun-Yi Tsai, Rachel Junod, Martine Jacot-Guillarmod, Charles Beniere, Sonia Ziadi, Massimo Bongiovanni
Enterobiasis is one of the most common human parasitic infections. It is considered an intestinal parasite, but cases of extra-intestinal affections exist, notably infections of the female genital tract. Enterobius vermicularis (EV) eggs (or ova) have been found in the cervical smears of two patients in our institute during the last 16 years. No gynaecological or gastrointestinal symptoms were reported, and there was no known intestinal infection in these two cases. A review of the available literature revealed rare cases of vaginal enterobiasis, with a wide range of clinical presentations, many patients being asymptomatic...
September 14, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28905047/use-of-community-health-workers-and-patient-navigators-to-improve-cancer-outcomes-among-patients-served-by-federally-qualified-health-centers-a-systematic-literature-review
#5
REVIEW
Katherine B Roland, Erin L Milliken, Elizabeth A Rohan, Amy DeGroff, Susan White, Stephanie Melillo, William E Rorie, Carmita-Anita C Signes, Paul A Young
Introduction: In the United States, disparities in cancer screening, morbidity, and mortality are well documented, and often are related to race/ethnicity and socioeconomic indicators including income, education, and healthcare access. Public health approaches that address social determinants of health have the greatest potential public health benefit, and can positively impact health disparities. As public health interventions, community health workers (CHWs), and patient navigators (PNs) work to address disparities and improve cancer outcomes through education, connecting patients to and navigating them through the healthcare system, supporting patient adherence to screening and diagnostic services, and providing social support and linkages to financial and community resources...
2017: Health Equity
https://www.readbyqxmd.com/read/28904849/influence-of-socioeconomic-status-comorbidity-and-disability-on-late-stage-cancer-diagnosis
#6
Bo Ram Park, So Young Kim, Dong Wook Shin, Hyung Kook Yang, Jong Hyock Park
OBJECTIVES: Understanding factors affecting advanced stage at diagnosis is vital to improve cancer outcomes and overall survival. We investigated the factors affecting later-stage cancer diagnosis. METHODS: Patients completed self-reported questionnaires. We collected cancer stage data from medical records review. Logistic regression analyses were performed to identify factors associated with later stage cancer at diagnosis by gender. RESULTS: In total, 1,870 cancer patients were included in the study; 55...
August 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/28903428/comparison-of-clinical-utilities-of-the-platelet-count-and-platelet-lymphocyte-ratio-for-predicting-survival-in-patients-with-cervical-cancer-a-single-institutional-study-and-literature-review
#7
Katsumi Kozasa, Seiji Mabuchi, Naoko Komura, Eriko Yokoi, Kuroda Hiromasa, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Eiji Kobayashi, Tadashi Kimura
OBJECTIVE: To compare the clinical utilities of the platelet count and platelet-lymphocyte ratio (PLR) for predicting survival in patients with cervical cancer. RESULTS: Multivariate analyses demonstrated that thrombocytosis and elevated PLR were found to be independent prognostic factors for progression-free survival (PFS, P = 0.0077, P = 0.044) and overall survival (OS, P = 0.025, P = 0.019) in separate Multivariate analyses. In the ROC analysis, the platelet count showed a significantly greater area under the ROC curve (AUC) value than that of PLR for predicting patient recurrence (0...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28900610/the-role-of-intraoperative-thyroglobuline-level-of-lymph-node-in-the-management-of-papillary-thyroid-cancer-determination-of-a-cutoff-point
#8
Mohsen Kolahdouzan, Mehdi Sadeghi, Behrooz Kalidari, Behnam Sanei, Elyas Mostafapour, Ashraf Aminorroaya
BACKGROUND: Some studies have shown that a preoperative high concentration of thyroglobulin (Tg) in wash out of fine-needle aspiration cytology of cervical lymph nodes mandate therapeutic lymph node dissection. However, there is disagreement about the minimum concentration of Tg which could have diagnostic value. Hence, according to our literature review, this study is the first one which designed to do intraoperatively. Therefore, this study was conducted and aimed to determine the clinical diagnostic value of Tg lymph nodes in the diagnosis of metastatic thyroid cancer...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28894824/avoidance-of-postoperative-irradiation-for-cervical-lymph-node-metastases-of-human-papillomavirus-related-tonsillar-cancer
#9
Koji Ebisumoto, Kenji Okami, Daisuke Maki, Kosuke Saito, Fukuko Shimizu, Takanobu Teramura, Shoji Kaneda, Masahiro Iida
BACKGROUND: Several reports have suggested that selected patients with human papillomavirus-related oropharyngeal cancer can be managed with surgery alone. We retrospectively reviewed tonsillar cancer cases to analyze treatment de-intensification after transoral resection. METHODS: Eighteen patients with tonsillar cancer who had undergone transoral resection were included. The patients' characteristics, p16 status, adverse features, clinical course, overall survival, and relapse-free survival according to p16 status were retrospectively examined...
April 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28891195/prevalence-of-synchronous-bilateral-tonsil-squamous-cell-carcinoma-a-retrospective-study
#10
Malene Sine Rokkjaer, Tejs Ehlers Klug
OBJECTIVES: The prevalence of synchronous bilateral tonsil cancer remains unexplored. To date, only 38 cases have been described in the literature. With an aim to substantiate the Danish recommendation of performing bilateral tonsillectomy in patients with suspected or proven tonsil cancer and in patients with cervical carcinoma metastasis from an unknown primary tumour, the current study was undertaken to determine the prevalence of synchronous bilateral tonsil cancer. DESIGN: A retrospective review of all patients diagnosed with tonsil cancer in the period 2000-2015, Aarhus University Hospital, Denmark, was performed...
September 11, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28889717/-a-case-of-primary-schwannoma-of-the-urinary-bladder
#11
Yoshitaka Matsumoto, Natsui Waku, Koji Kawai, Atsushi Ikeda, Tomokazu Kimura, Ryutaro Ishitsuka, Takahiro Kojima, Takahiro Suetomi, Akira Joraku, Jun Miyazaki, Mai Sakashita, Hiroyuki Nishiyama
A 68-year-old woman presented with a bladder tumor. She was asymptomatic, and the tumor was incidentally detected with radiological imaging performed during treatment of cervical cancer. Magnetic resonance imaging and computed tomography revealed a solitary submucosal tumor located in the anterior wall of the urinary bladder, with homogeneous contrast enhancement. Cystoscopy showed a submucosal tumor covered by normal mucosa. A paraganglioma was considered in the differential diagnosis, but symptoms suggesting hypercatecholaminemia were not apparent...
August 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28888417/american-brachytherapy-society-recurrent-carcinoma-of-the-endometrium-task-force-patterns-of-care-and-review-of-the-literature
#12
Mitchell Kamrava, Sushil Beriwal, Beth Erickson, David Gaffney, Anuja Jhingran, Ann Klopp, Sang June Park, Akila Viswanathan, Catheryn Yashar, Lilie Lin
PURPOSE: The purpose of this American Brachytherapy Society task force is to present a literature review and patterns of care by a panel of experts for the management of vaginal recurrence of endometrial cancer. METHODS AND MATERIALS: In 2016, the American Brachytherapy Society Board selected a panel of experts in gynecologic brachytherapy to update our current state of knowledge for managing vaginal recurrence of endometrial cancer. Practice patterns were evaluated via an online survey and clinical updates occurred through a combination of literature review and clinical experience and/or expertise...
September 6, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28885082/human-papillomavirus-testing-by-veterans-administration-women-s-health-providers-are-they-adhering-to-guidelines
#13
Laura D Hallett, Megan R Gerber
BACKGROUND: Evidence-based guidelines have been created by professional societies, including the United States Preventive Services Task Force (USPSTF) and American Society for Colposcopy and Cervical Pathology (ASCCP), for use of human papillomavirus (HPV) cotesting in cervical cancer screening. We investigated whether Veterans Health Administration (VA) providers at one VA medical center follow these guidelines. MATERIALS AND METHODS: Retrospective chart review of women aged 21-65 who had an HPV test ordered with pap testing in fiscal year 2014 at one Veterans Administration (VA) medical center to evaluate concordance of HPV ordering with screening (USPSTF) and management (ASCCP) guidelines...
September 8, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28881667/a-high-plasma-d-dimer-level-predicts-poor-prognosis-in-gynecological-tumors-in-east-asia-area-a-systematic-review-and-meta-analysis
#14
Lei Xu, Fan He, Hongcai Wang, Bei Gao, Huini Wu, Shuping Zhao
High pre-treatment plasma D-dimer levels have been reported as a factor associated with a poor prognosis in different types of malignancies, including pancreatic, gastric, colorectal, lung, and nasopharyngeal carcinoma. Here, we performed a meta-analysis to determine the association of plasma D-dimer levels and long term survival in gynecological cancers, including ovarian, cervical and endometrial carcinoma. We searched all eligible publications in PubMed and Web of Science Databases up to August 2016. Primary outcomes, including overall survival (OS), disease-free survival and hazard ratios (HR) of were extracted and analyzed...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28875439/current-status-and-future-prospects-for-human-papillomavirus-vaccines
#15
REVIEW
Hyoung Jin Kim, Hong-Jin Kim
Cervical cancer is the fourth most frequent cancer among women worldwide. Human papillomaviruses (HPVs) cause almost all cervical cancers in low-income countries. Three prophylactic HPV virus-like particle-based vaccines have been licensed to date, and they have all shown high efficacy and reliable safety profiles. However, isolated safety issues have resulted in a reluctance to use these vaccinations. In addition, the high prices of the vaccinations have caused the inequitable distribution of the vaccine: the prices are unaffordable for low-income countries...
September 5, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/28873092/effect-of-cervical-cancer-education-and-provider-recommendation-for-screening-on-screening-rates-a-systematic-review-and-meta-analysis
#16
Jonah Musa, Chad J Achenbach, Linda C O'Dwyer, Charlesnika T Evans, Megan McHugh, Lifang Hou, Melissa A Simon, Robert L Murphy, Neil Jordan
BACKGROUND: Although cervical cancer is largely preventable through screening, detection and treatment of precancerous abnormalities, it remains one of the top causes of cancer-related morbidity and mortality globally. OBJECTIVES: The objective of this systematic review is to understand the evidence of the effect of cervical cancer education compared to control conditions on cervical cancer screening rates in eligible women population at risk of cervical cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28873027/the-cgl1-hela-%C3%A3-normal-skin-fibroblast-human-hybrid-cell-line-a-history-of-ionizing-radiation-induced-effects-on-neoplastic-transformation-and-novel-future-directions-in-snolab
#17
Jake S Pirkkanen, Douglas R Boreham, Marc S Mendonca
Cellular transformation assays have been utilized for many years as powerful in vitro methods for examining neoplastic transformation potential/frequency and mechanisms of carcinogenesis for both chemical and radiological carcinogens. These mouse and human cell based assays are labor intensive but do provide quantitative information on the numbers of neoplastically transformed foci produced after carcinogenic exposure and potential molecular mechanisms involved. Several mouse and human cell systems have been generated to undertake these studies, and they vary in experimental length and endpoint assessment...
September 5, 2017: Radiation Research
https://www.readbyqxmd.com/read/28870055/-lymph-node-metastasis-and-prognostic-factors-for-t1-esophageal-cancer
#18
X F Duan, X B Shang, P Tang, H J Jiang, L Gong, J Yue, M Q Ma, Z T Yu
Objective: To evaluate the lymph node metastasis (LNM) pattern and related prognostic factors for T1 esophageal cancer. Methods: Clinical data of 143 cases of pT1 esophageal cancer patients (120 male and 23 female patients with median age of 60 years) who underwent esophagectomy and lymph node resection during January 2011 and July 2016 at the Department of Esophageal Cancer of Tianjin Medical University Cancer Institute and Hospital were reviewed, including 50 cases of T1a patients and 93 cases of T1b patients...
September 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28868193/cervical-cancer-metastasis-to-the-brain-a-case-report-and-review-of-literature
#19
REVIEW
Kaleigh Fetcko, Dibson D Gondim, Jose M Bonnin, Mahua Dey
BACKGROUND: Intracranial metastasis from cervical cancer is a rare occurrence. METHODS: In this study we describe a case of cervical cancer metastasis to the brain and perform an extensive review of literature from 1956 to 2016, to characterize clearly the clinical presentation, treatment options, molecular markers, targeted therapies, and survival of patients with this condition. RESULTS: An elderly woman with history of cervical cancer in remission, presented 2 years later with a right temporo-parietal tumor, which was treated with surgery and subsequent stereotactic radiosurgery (SRS) to the resection cavity...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28866431/outcomes-of-stage-ii-endometrial-cancer-the-upmc-hillman-cancer-center-experience
#20
Katherine S Chen, Hebist Berhane, Beant S Gill, Alexander Olawaiye, Paniti Sukumvanich, Joseph L Kelley, Michelle M Boisen, Madeleine Courtney-Brooks, John T Comerci, Robert Edwards, Jessica Berger, Sushil Beriwal
PURPOSE: Previous studies of stage II endometrial cancer have included cancers with cervical glandular involvement, a factor no longer associated with risk of recurrence. In order to better assess relapse patterns and the impact of adjuvant therapy, a retrospective analysis was conducted for patients with modern stage II endometrial cancer, defined as cervical stromal invasion. MATERIALS AND METHODS: Patients diagnosed with surgically staged FIGO stage II endometrial cancer at the UPMC Hillman Cancer Center from 1990-2013 were reviewed...
August 30, 2017: Gynecologic Oncology
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