Qing-Hua Liang, Qiu-Rong Li, Zhong Chen, Li-Juan Lv, Yu Lin, Hong-Lv Jiang, Ke-Xin Wang, Ming-Yue Xiao, Nai-Xin Kang, Peng-Fei Tu, Shi-Liang Ji, Ke-Jun Deng, Hong-Wei Gao, Li Zhang, Kun Li, Fei Ge, Guo-Qiang Xu, Shi-Lin Yang, Yan-Li Liu, Qiong-Ming Xu
OBJECTIVES: Colitis is a global disease usually accompanied by intestinal epithelial damage and intestinal inflammation, and an increasing number of studies have found natural products to be highly effective in treating colitis. Anemoside B4 (AB4), an abundant saponin isolated from Pulsatilla chinensis (Bunge), which was found to have strong anti-inflammatory activity. However, the exact molecular mechanisms and direct targets of AB4 in the treatment of colitis remain to be discovered...
December 29, 2023: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]