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topiramate for the prophylaxis of episodic migraine in adults

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https://www.readbyqxmd.com/read/27233055/withdrawn-anticonvulsant-drugs-for-migraine-prophylaxis
#1
REVIEW
Edward P Chronicle, Wim M Mulleners
No abstract text is available yet for this article.
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26172390/a-comparative-effectiveness-meta-analysis-of-drugs-for-the-prophylaxis-of-migraine-headache
#2
COMPARATIVE STUDY
Jeffrey L Jackson, Elizabeth Cogbill, Rafael Santana-Davila, Christina Eldredge, William Collier, Andrew Gradall, Neha Sehgal, Jessica Kuester
OBJECTIVE: To compare the effectiveness and side effects of migraine prophylactic medications. DESIGN: We performed a network meta-analysis. Data were extracted independently in duplicate and quality was assessed using both the JADAD and Cochrane Risk of Bias instruments. Data were pooled and network meta-analysis performed using random effects models. DATA SOURCES: PUBMED, EMBASE, Cochrane Trial Registry, bibliography of retrieved articles through 18 May 2014...
2015: PloS One
https://www.readbyqxmd.com/read/25115844/antiepileptics-in-migraine-prophylaxis-an-updated-cochrane-review
#3
REVIEW
Wim M Mulleners, Douglas C McCrory, Mattias Linde
INTRODUCTION: The efficacy of several antiepileptics in the preventive treatment of episodic migraine in adults has been systematically reviewed. Because many trial reports have been published since then, an updated systematic review was warranted. METHODS: We searched the Cochrane Central Register of Controlled Trials, PubMed/MEDLINE (1966 to January 15, 2013), MEDLINE In-Process (current week, January 15, 2013), and EMBASE (1974 to January 15, 2013) and hand-searched Headache and Cephalalgia through January 2013...
January 2015: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/25077498/topiramate-for-the-prophylaxis-of-episodic-migraine-in-adults
#4
COMMENT
Elizabeth Salisbury-Afshar
No abstract text is available yet for this article.
July 1, 2014: American Family Physician
https://www.readbyqxmd.com/read/24255866/preventive-effect-of-cyproheptadine-hydrochloride-in-refractory-patients-with-frequent-migraine
#5
Hirohisa Okuma, Kazuyuki Iijima, Takashi Yasuda, Kentaro Tokuoka, Yasuhisa Kitagawa
Cyproheptadine hydrochloride (CH) is rarely used to treat adult patients with migraine in Japan because it causes sleepiness. In this study, we investigated the preventive effect of CH in 12 patients who had failed to respond to conventional preventive treatments among 103 migraine patients treated at our hospital. These 12 subjects had all received unsuccessful migraine prophylaxis with lomerizine, valproic acid and topiramate, or had discontinued these treatments due to adverse reactions. Initially, the subjects were given 4 mg CH before sleeping...
2013: SpringerPlus
https://www.readbyqxmd.com/read/23797677/valproate-valproic-acid-or-sodium-valproate-or-a-combination-of-the-two-for-the-prophylaxis-of-episodic-migraine-in-adults
#6
REVIEW
Mattias Linde, Wim M Mulleners, Edward P Chronicle, Douglas C McCrory
BACKGROUND: Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of a Cochrane review first published in 2004, and previously updated (conclusions not changed) in 2007. OBJECTIVES: To describe and assess the evidence from controlled trials on the efficacy and tolerability of valproate (valproic acid or sodium valproate or a combination of the two) for preventing migraine attacks in adult patients with episodic migraine...
2013: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/23797676/topiramate-for-the-prophylaxis-of-episodic-migraine-in-adults
#7
REVIEW
Mattias Linde, Wim M Mulleners, Edward P Chronicle, Douglas C McCrory
BACKGROUND: Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of a Cochrane review first published in 2004, and previously updated (conclusions not changed) in 2007. OBJECTIVES: To describe and assess the evidence from controlled trials on the efficacy and tolerability of topiramate for preventing migraine attacks in adult patients with episodic migraine...
2013: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/23797674/antiepileptics-other-than-gabapentin-pregabalin-topiramate-and-valproate-for-the-prophylaxis-of-episodic-migraine-in-adults
#8
REVIEW
Mattias Linde, Wim M Mulleners, Edward P Chronicle, Douglas C McCrory
BACKGROUND: Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of a Cochrane review first published in 2004, and previously updated (conclusions not changed) in 2007. OBJECTIVES: To describe and assess the evidence from controlled trials on the efficacy and tolerability of antiepileptic drugs other than gabapentin, pregabalin, topiramate, and valproate (which are the subjects of separate Cochrane reviews) for preventing migraine attacks in adult patients with episodic migraine...
2013: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/23559999/effective-dose-of-topiramate-in-pediatric-migraine-prophylaxis
#9
Ali Abbaskhanian, Hamid Reza Sadeghi, Ali Erfani, Mohammad Sadegh Rezai
OBJECTIVE: Migraine is a common neurological disorder in childhood and adolescence. Topiramate is a new anticonvulsant drug, recently being used in migraine prophylaxis in adults, although it is not approved by the Food and Drug Administration for prevention of pediatric migraine. The present study was planned and performed to evaluate the efficacy of low-dose topiramate in pediatric migraine prophylaxis. MATERIALS AND METHODS: A prospective study, including 60 patients with migraine headaches was performed for a period of two months...
September 2012: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/23458496/patterns-of-use-and-reasons-for-discontinuation-of-prophylactic-medications-for-episodic-migraine-and-chronic-migraine-results-from-the-second-international-burden-of-migraine-study-ibms-ii
#10
Andrew M Blumenfeld, Lisa M Bloudek, Werner J Becker, Dawn C Buse, Sepideh F Varon, Gregory A Maglinte, Teresa K Wilcox, Ariane K Kawata, Richard B Lipton
OBJECTIVE: Our objective was to characterize patterns of preventive medication use in persons with episodic migraine (EM) and chronic migraine (CM). BACKGROUND: Several classes of medications are used both on- and off-label for the prevention of migraine, including β-blockers (eg, propranolol, timolol), tricyclic antidepressants (eg, amitriptyline), anti-epileptic drugs (eg, topiramate, valproic acid), and neurotoxins (eg, onabotulinumtoxinA). METHODS: Preventive medication use and reasons for discontinuation were collected in an international, Web-based, cross-sectional survey of adults with migraine during 2010...
April 2013: Headache
https://www.readbyqxmd.com/read/21770931/implications-of-current-clinical-trials-focused-on-medication-overuse-and-therapeutic-prophylaxis
#11
Sheena K Aurora
Chronic migraine (CM) is a complex disorder requiring a multifaceted management approach encompassing lifestyle modification, trigger avoidance, behavioral therapy, pharmacotherapy, patient education and support, management of expectations, and close follow-up. The lack of pharmacotherapies approved by the US Food and Drug Administration (FDA) hinders CM prophylaxis and management. Topiramate, gabapentin, tizanidine, fluoxetine, amitriptyline, and onabotulinumtoxinA have been evaluated for prophylactic treatment of CM in randomized, double-blind, placebo-controlled or active comparator-controlled trials...
July 2011: Headache
https://www.readbyqxmd.com/read/21457240/topiramate-vs-divalproex-sodium-in-the-preventive-treatment-of-migraine-a-prospective-real-world-study
#12
MULTICENTER STUDY
Abouch V Krymchantowski, Carla C Jevoux
BACKGROUND AND OBJECTIVES: Certain neuromodulators, most notably topiramate (TPM) and divalproex sodium (DVP), are effective preventive agents for migraine. Published data from head-to-head studies comparing TPM and DVP are not available. The purpose of this study was to compare TPM and DVP for the prophyaxis of migraine in a "real-world" setting. METHODS: At 2 centers and over a period of 12 months we prospectively evaluated and treated a consecutive series of migraine patients...
April 2011: Headache
https://www.readbyqxmd.com/read/21112462/topiramate-induced-confusion-following-a-single-ingestion-of-400-mg
#13
Matthew D Pierson, Andrew J Muzyk, Megan Lockamy, Xavier A Preud'homme
BACKGROUND: Topiramate is an anticonvulsant medication commonly used for a variety of neurological disorders including migraine prophylaxis. Broadened use of topiramate has brought an increased awareness of toxicity from this medication, particularly central nervous system side effects and metabolic acidosis. OBJECTIVE: We describe a case of topiramate toxicity occurring in a 22-year-old female following the ingestion of two 200 mg tablets, which she was prescribed for the treatment of migraines...
November 2010: General Hospital Psychiatry
https://www.readbyqxmd.com/read/20592323/topiramate-induced-myoclonus-and-psychosis-during-migraine-prophylaxis
#14
April D Miller, Valerie M Prost, P Brandon Bookstaver, Kenneth J Gaines
PURPOSE: A case of topiramate-induced myoclonus and acute psychosis in a patient taking the recommended dosage of topiramate for migraine prophylaxis is reported. SUMMARY: A 29-year-old Caucasian, wheelchair-bound woman with diplegic cerebral palsy and a history of migraines was admitted to the hospital after developing paranoid thoughts and episodes of myoclonus two weeks after an increase in her topiramate dosage (25 mg twice daily to 50 mg twice daily). Her physical examination upon admission was unremarkable, with the exception of a temperature of 38...
July 15, 2010: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/19788470/variation-in-almotriptan-effectiveness-according-to-different-prophylactic-treatments
#15
COMPARATIVE STUDY
Pedro Emilio Bermejo, Rodolfo Dorado, Jose Maria Gomez-Arguelles
OBJECTIVE: To evaluate the effect of different migraine prophylaxis medications on subject responsiveness to almotriptan. BACKGROUND: There is evidence supporting an increase of responsiveness of symptomatic medications for migraine attacks by some prophylactic treatments although this has not been probed. METHODS: A total of 345 patients (230 women, mean age 37.3) with episodic or chronic migraine were classified according to the prophylaxis they were taking in the following groups: (1) no prophylactic medication; (2) propranolol; (3) topiramate; (4) flunarizine...
October 2009: Headache
https://www.readbyqxmd.com/read/18713156/a-double-blind-randomized-trial-of-low-dose-topiramate-vs-propranolol-in-migraine-prophylaxis
#16
RANDOMIZED CONTROLLED TRIAL
F Ashtari, V Shaygannejad, M Akbari
OBJECTIVE: To assess the efficacy and safety of low-dose topiramate in migraine prophylaxis vs propranolol. PATIENTS AND METHODS: A randomized, double-blind, clinical trial including 62 patients with frequent migraine headaches (> or = 3 attacks per month) was performed for a period of 8 weeks. The patients were randomly divided into two treatment groups - treated by topiramate 50 mg/day and propranolol 80 mg/day, respectively. The patients were assessed at 0, 4, and 8 weeks of the study...
November 2008: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/18651939/cluster-headache
#17
REVIEW
Elizabeth Leroux, Anne Ducros
Cluster headache (CH) is a primary headache disease characterized by recurrent short-lasting attacks (15 to 180 minutes) of excruciating unilateral periorbital pain accompanied by ipsilateral autonomic signs (lacrimation, nasal congestion, ptosis, miosis, lid edema, redness of the eye). It affects young adults, predominantly males. Prevalence is estimated at 0.5-1.0/1,000. CH has a circannual and circadian periodicity, attacks being clustered (hence the name) in bouts that can occur during specific months of the year...
July 23, 2008: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/17016684/chronic-migraine-prevention-with-topiramate
#18
Mario F P Peres, Juliane P P Mercante, Fabiano C Tanuri, Marlio Nunes, Eliova Zukerman
Chronic migraine (CM) is a disabling condition with not many treatment strategies available. Topiramate is effective in episodic migraine prevention, however little is known about its effect in CM. An open label study was performed. Sixty-four patients diagnosed with CM or probable CM according to the IHS diagnostic criteria were enrolled, 50 patients were available for analysis and an intention-to-treat methodology was applied. The primary endpoint considered was the number of patients with a decrease in headache frequency higher than 50%...
September 2006: Journal of Headache and Pain
https://www.readbyqxmd.com/read/16243217/effectiveness-of-topiramate-in-the-treatment-of-pediatric-chronic-daily-headache
#19
John C Borzy, Thomas K Koch, James R Schimschock
This study reports on the efficacy and safety of low-dose topiramate in the treatment of pediatric patients with chronic daily headache. Topiramate is one of the new antiepileptic drugs commonly being used for migraine prophylaxis in adults as well as children and was recently approved by the Food and Drug Administration for migraine treatment in adults. This report presents our experience with low-dose topiramate for the treatment of chronic daily headache using a retrospective parental survey of 21 patients ranging in age from 6 to 18 years...
November 2005: Pediatric Neurology
https://www.readbyqxmd.com/read/15316798/topiramate-in-migraine-prophylaxis-results-from-a-placebo-controlled-trial-with-propranolol-as-an-active-control
#20
RANDOMIZED CONTROLLED TRIAL
Hans-Christoph Diener, Peer Tfelt-Hansen, Carl Dahlöf, Miguel J A Láinez, Giorgio Sandrini, Shuu-Jiun Wang, Walter Neto, Ujjwalla Vijapurkar, Aiden Doyle, David Jacobs
Topiramate (TPM) has shown efficacy in migraine prophylaxis in two large placebo-controlled, dose-ranging trials. We conducted a randomised, double-blind, multicentre trial to evaluate the efficacy and safety of two doses of topiramate vs placebo for migraine prophylaxis, with propranolol (PROP) as an active control. Subjects with episodic migraine with and without aura were randomised to TPM 100 mg/d, TPM 200 mg/d, PROP 160 mg/d (active control), or placebo. The primary efficacy measure was the change in mean monthly migraine frequency from the baseline phase relative to the double-blind treatment phase...
August 2004: Journal of Neurology
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