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https://www.readbyqxmd.com/read/29232534/detection-of-dengue-virus-in-bat-flies-diptera-streblidae-of-common-vampire-bats-desmodus-rotundus-in-progreso-hidalgo-mexico
#1
Judith Abundes-Gallegos, Monica Salas-Rojas, Guillermo Galvez-Romero, Leonardo Perea-Martínez, Cirani Y Obregón-Morales, Juan B Morales-Malacara, Bruno B Chomel, Matthew J Stuckey, Hayde Moreno-Sandoval, Anahi García-Baltazar, Benjamin Nogueda-Torres, Gerardo Zuñiga, Alvaro Aguilar-Setién
Blood-feeding arthropods play a major role in the transmission of several flaviviruses, which represent an important problem for human health. Currently, dengue is one of the most important arboviral emerging diseases worldwide. Furthermore, some previous studies have reported the presence of viral nucleic acids and antibodies against dengue virus (DENV) in wild animals. Our knowledge of the role played by wildlife reservoirs in the sylvatic transmission and maintenance of DENV remains limited. Our objective was to screen blood-feeding ectoparasites (bat flies) and their common vampire bat (Desmodus rotundus) hosts, for flaviviruses in Hidalgo, Mexico...
December 12, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29232415/serological-detection-of-tick-borne-relapsing-fever-in-texan-domestic-dogs
#2
Maria D Esteve-Gasent, Chloe B Snell, Shakirat A Adetunji, Julie Piccione
Tick-Borne Relapsing Fever (TBRF) is caused by spirochetes in the genus Borrelia. Very limited information exists on the incidence of this disease in humans and domestic dogs in the United States. The main objective of this study is to evaluate exposure of dogs to Borrelia turicatae, a causative agent of TBRF, in Texas. To this end, 878 canine serum samples were submitted to Texas A&M Veterinary Medical Diagnostic Laboratory from October 2011 to September 2012 for suspected tick-borne illnesses. The recombinant Borrelial antigen glycerophosphodiester phosphodiesterase (GlpQ) was expressed, purified, and used as a diagnostic antigen in both ELISA assays and Immunoblot analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29232412/the-opposite-effects-of-nandrolone-decanoate-and-exercise-on-anxiety-levels-in-rats-may-involve-alterations-in-hippocampal-parvalbumin-positive-interneurons
#3
Dragica Selakovic, Jovana Joksimovic, Ivan Zaletel, Nela Puskas, Milovan Matovic, Gvozden Rosic
The aim of this study was to evaluate the behavioral effects of chronic (six weeks) nandrolone decanoate (ND, 20 mg/kg, s.c., weekly in single dose) administration (in order to mimic heavy human abuse), and exercise (swimming protocol of 60 minutes a day, five days in a row/two days break), applied alone and simultaneously with ND, in male rats (n = 40). Also, we evaluated the effects of those protocols on hippocampal parvalbumin (PV) content and the possible connection between the alterations in certain parts of hippocampal GABAergic system and behavioral patterns...
2017: PloS One
https://www.readbyqxmd.com/read/29232167/tigecycline-susceptibility-of-klebsiella-pneumoniae-complex-and-escherichia-coli-isolates-from-companion-animals-the-prevalence-of-tigecycline-nonsusceptible-k-pneumoniae-complex-including-internationally-expanding-human-pathogenic-lineages
#4
Toyotaka Sato, Kazuki Harada, Masaru Usui, Yuzo Tsuyuki, Tsukasa Shiraishi, Yutaka Tamura, Shin-Ichi Yokota
Transmission of tigecycline-nonsusceptible pathogenic Enterobacteriaceae from companion animals to human should be a concern because tigecycline is a last-line drug for treating multidrug-resistant Enterobacteriaceae in human medicine. However, tigecycline susceptibility of Enterobacteriaceae isolated from companion animals has not been investigated. In this study, we investigated the tigecycline susceptibility of Klebsiella pneumoniae complex and Escherichia coli isolates from dogs and cats, and evaluated their human pathogenicity potential...
December 12, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29231996/molecular-mechanisms-of-tributyltin-induced-alterations-in-cholesterol-homeostasis-and-steroidogenesis-in-hamster-testis-in-vivo-and-in-vitro-studies
#5
V Kanimozhi, K Palanivel, M A Akbarsha, B Kadalmani
Tributyltins (TBT) are ubiquitous and persistent environmental contaminants that disturb normal endocrine function including gonadal function in humans and marine organisms. TBT was administered through oral route to male Syrian hamsters at daily doses of 50, 100 and 150 ppm/kg for 65 days. Changes in testis morphology, immunohistochemistry of iNOS, 3β-HSD and 17β-HSD, cholesterol transport receptor, nuclear receptors, and transcription factors were analyzed. TBT treatment affected each of these parameters to significant levels in a dose-dependent manner compared to vehicle treated control...
December 12, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29231967/therapeutic-potential-of-porcine-bronchoalveolar-fluid-derived-mesenchymal-stromal-cells-in-a-pig-model-of-lps-induced-ali
#6
Mahesh Khatri, Levi Arthur Richardson
In this study, we isolated mesenchymal stromal (stem) cells (MSCs) from broncho-alveolar lavage fluid (BAL) of 2-6 week-old commercial pigs. BAL-MSCs displayed fibroblastic morphology and possessed self-renewal properties. Similar to bone-marrow MSCs, BAL-MSCs expressed mesenchymal markers and both cell types lacked the expression of hematopoetic markers. BAL-MSCs, when cultured in differentiation induction media, differentiated into adipocytes, osteocytes and chondrocytes. Next, we examined if BAL-MSCs have the ability to treat lipopolysaccharide (LPS)-induced acute lung injury (ALI) in a pig model...
December 12, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29231904/protective-effects-of-%C3%AF-3-pufa-in-anthracycline-induced-cardiotoxicity-a-critical-review
#7
REVIEW
Simona Serini, Renata Ottes Vasconcelos, Renata Nascimento Gomes, Gabriella Calviello
It has been demonstrated that ω-3 polyunsaturated fatty acids (ω-3 PUFA) may exert a beneficial role as adjuvants in the prevention and treatment of many disorders, including cardiovascular diseases and cancer. Particularly, several in vitro and in vivo preclinical studies have shown the antitumor activity of ω-3 PUFA in different kinds of cancers, and several human studies have shown that ω-3 PUFA are able to decrease the risk of a series of cardiovascular diseases. Several mechanisms have been proposed to explain their pleiotropic beneficial effects...
December 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29231791/glucagon-like-peptide-2-and-neoplasia-a-systematic-review
#8
Linea Landgrebe Ring, Nikolaj Nerup, Palle Bekker Jeppesen, Lars Bo Svendsen, Michael Patrick Achiam
Glucagon like peptide-2 is synthesized from enteroendocrine L cells primarily located in the ileum and large intestine. GLP-2 stimulates crypt cell proliferation, increases intestinal blood flow, enhances gut barrier function, induces mucosal healing, and exerts an anti-apoptotic effect. Due to these effects GLP-2 is used in the treatment of short bowel syndrome (SBS). Areas covered The aim of this systematic review was to provide information on the potential risk of intestinal neoplasia in patients receiving treatment with GLP-2...
December 12, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29230933/biology-and-pathological-implications-of-brown-adipose-tissue-promises-and-caveats-for-the-control-of-obesity-and-its-associated-complications
#9
Pablo Tapia, Marta Fernández-Galilea, Fermín Robledo, Pablo Mardones, José E Galgani, Víctor A Cortés
The discovery of metabolically active brown adipose tissue (BAT) in adult humans has fuelled the research of diverse aspects of this previously neglected tissue. BAT is solely present in mammals and its clearest physiological role is non-shivering thermogenesis, owing to the capacity of brown adipocytes to dissipate metabolic energy as heat. Recently, a number of other possible functions have been proposed, including direct regulation of glucose and lipid homeostasis and the secretion of a number of factors with diverse regulatory actions...
December 11, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/29230898/molecular-characterization-of-enterocytozoon-bieneusi-in-wild-carnivores-in-spain
#10
Mónica Santín, Rafael Calero-Bernal, David Carmena, Marta Mateo, Ana Balseiro, Marta Barral, José Francisco Lima Barbero, Miguel Ángel Habela
Microsporidia comprises a diverse group of obligate intracellular parasites that infect a broad range of invertebrates and vertebrates. Among Microsporidia, Enterocytozoon bieneusi is the most frequently detected species in humans and animals worldwide bringing into question the possible role of animal reservoirs in the epidemiology of this pathogen. Although E. bieneusi is an emerging zoonotic pathogen able to infect many domestic and wild mammals that could act as reservoir of infection for humans and other animals, only few studies have documented its occurrence in wild carnivores...
December 12, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/29230608/combinatorial-therapy-with-two-pro-coagulants-and-one-osmotic-agent-reduces-the-extent-of-the-lesion-in-the-acute-phase-of-spinal-cord-injury-in-the-rat
#11
Mathieu Boutonnet, Elisabeth Laemmel, Eric Vicaut, Jacques Duranteau, Marc Soubeyrand
BACKGROUND: Spinal cord injury (SCI) is a complex disease that leads to a motor, sensitive, and vegetative impairment. So far, single therapies are ineffective for treating SCI in humans and a multifactorial therapeutic approach may be required. The aim of this work was to assess the effect of a triple therapy (TT) associating two pro-coagulant therapies (tranexamic acid and fibrinogen) with an anti-edema therapy (hypertonic saline solution), on the extent of the lesion 24 h post-injury...
December 11, 2017: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/29230579/prevalence-of-cysticercosis-in-estonian-pigs-and-cattle
#12
Elisabeth Dorbek-Kolin, Tuuli Åhlberg, Lea Tummeleht, Dennis Tappe, Maria Vang Johansen, Brian Lassen
Taenia solium has been ranked as the most important foodborne parasite and Taenia saginata as the most commonly found human Taenia tapeworm worldwide. The last official reports of taeniosis from Estonia were in 2003 for T. solium and 2012 for T. saginata. By law, all animal cases of cysticercosis must be registered and reported when found. Our aim was to estimate the prevalence of cysticercosis in Estonia caused by T. solium in pigs and T. saginata in cattle. The four slaughterhouses participating in the study slaughter between them approximately 80% of pigs and cattle in Estonia annually...
December 11, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29230545/influence-of-different-types-of-light-on-the-response-of-the-pulp-tissue-in-dental-bleaching-a-systematic-review
#13
Francine Benetti, Cleidiel Aparecido Araújo Lemos, Marjorie de Oliveira Gallinari, Amanda Miyuki Terayama, André Luiz Fraga Briso, Rogério de Castilho Jacinto, Gustavo Sivieri-Araújo, Luciano Tavares Angelo Cintra
OBJECTIVES: This systematic review (PROSPERO register: CRD42016053140) investigated the influence of different types of light on the pulp tissue during dental bleaching. MATERIALS AND METHODS: Two independent authors conducted a systematic search and risk of bias evaluations. An electronic search was undertaken (PubMed/Medline, Embase, The Cochrane Library, and other databases) until May 2017. The population, intervention, comparison, outcomes (PICO) question was: "Does the light in dental bleaching change the response of the pulp to the bleaching procedure?" The intervention involved pulp tissue/cells after bleaching with light, while the comparison involved pulp tissue/cells after bleaching without light...
December 11, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29230430/triethylene-glycol-dimethacrylate-adjuvant-properties-and-effect-on-cytokine-production
#14
Sara Alizadehgharib, Anna-Karin Östberg, Ulf Dahlgren
Objective: Leakage of monomers from dental fillings due to incomplete curing is very common. The objective of the present study was to examine the cytokine profile in cells exposed to triethyleneglycol dimethacrylate (TEGDMA) and the adjuvant properties of TEGDMA. Materials and methods: Human peripheral blood mononuclear cells were exposed to TEGDMA (500 and 1000 μM) for 24 h in vitro. Bio-Plex Pro™ assays were used for analysis and detection of cytokines. In vivo, BALB/c mice were immunized subcutaneously in the base of the tail with TEGDMA in combination with ovalbumin (OVA)...
2018: Acta Biomaterialia Odontologica Scandinavica
https://www.readbyqxmd.com/read/29230402/animal-health-surveillance-in-scotland-in-2030-using-scenario-planning-to-develop-strategies-in-the-context-of-brexit
#15
Lisa A Boden, Harriet Auty, Aaron Reeves, Gustaf Rydevik, Paul Bessell, Iain J McKendrick
Animal health surveillance is necessary to protect human and animal health, rural economies, and the environment from the consequences of large-scale disease outbreaks. In Scotland, since the Kinnaird review in 2011, efforts have been made to engage with stakeholders to ensure that the strategic goals of surveillance are better aligned with the needs of the end-users and other beneficiaries. The aims of this study were to engage with Scottish surveillance stakeholders and multidisciplinary experts to inform the future long-term strategy for animal health surveillance in Scotland...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29230232/chemosensitization-of-fusarium-graminearum-to-chemical-fungicides-using-cyclic-lipopeptides-produced-by-bacillus-amyloliquefaciens-strain-jck-12
#16
Kihyun Kim, Yoonji Lee, Areum Ha, Ji-In Kim, Ae Ran Park, Nan Hee Yu, Hokyoung Son, Gyung Ja Choi, Hae Woong Park, Chul Won Lee, Theresa Lee, Yin-Won Lee, Jin-Cheol Kim
Fusarium head blight (FHB) caused by infection with Fusarium graminearum leads to enormous losses to crop growers, and may contaminate grains with a number of Fusarium mycotoxins that pose serious risks to human and animal health. Antagonistic bacteria that are used to prevent FHB offer attractive alternatives or supplements to synthetic fungicides for controlling FHB without the negative effects of chemical management. Out of 500 bacterial strains isolated from soil, Bacillus amyloliquefaciens JCK-12 showed strong antifungal activity and was considered a potential source for control strategies to reduce FHB...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29230179/transplacental-nutrient-transport-mechanisms-of-intrauterine-growth-restriction-in-rodent-models-and-humans
#17
REVIEW
Elke Winterhager, Alexandra Gellhaus
Although the causes of intrauterine growth restriction (IUGR) have been intensively investigated, important information is still lacking about the role of the placenta as a link from adverse maternal environment to adverse pregnancy outcomes of IUGR and preterm birth. IUGR is associated with an increased risk of cardiovascular, metabolic, and neurological diseases later in life. Determination of the most important pathways that regulate transplacental transport systems is necessary for identifying marker genes as diagnostic tools and for developing drugs that target the molecular pathways...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29230098/circular-rnas-a-novel-type-of-non-coding-rna-and-their-potential-implications-in-antiviral-immunity
#18
REVIEW
Man Wang, Fei Yu, Wei Wu, Yuan Zhang, Wenguang Chang, Murugavel Ponnusamy, Kun Wang, Peifeng Li
Circular RNAs (circRNAs), a novel type of non-coding RNAs (ncRNAs), are ubiquitously expressed in eukaryotic cells during post-transcriptional processes. Unlike linear RNAs, circRNAs form covalent-closed continuous loops without 5' to 3' polarities and poly (A) tails. With advances in high-throughput sequencing technology, numerous circRNAs have been identified in plants, animals and humans. Notably, circRNAs display cell-type, tissue-type and developmental-stage specific expression patterns in eukaryotic transcriptome, which reveals their significant regulatory functions in gene expression...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/29230010/serotype-and-virulence-genes-of-klebsiella-pneumoniae-isolated-from-mink-and-its-pathogenesis-in-mice-and-mink
#19
Wang Jian-Li, Shang Yuan-Yuan, Guo Shou-Yu, Diao Fei-Fei, Yu Jia-Yu, Wei Xue-Hua, Zhao Yong-Feng, Jiang Shi-Jin, Xie Zhi-Jing
In the study, 15 K. pneumoniae strains were isolated from the mink experiencing respiratory distress in mideastern Shandong province, China, and the prevalence of K. pneumoniae in the sampled mink was 11.9% (15/126). Fourteen (93.33%) of the 15 K. pneumoniae isolates were identified as serotype K2 and hypermucoviscosity phenotype. The 12 virulence-associated genes of the K. pneumoniae isolates were tested. The prevalence of the wabG gene for the isolates were 100% (15/15), the ureA gene 100% (15/15), the rmpA gene 93...
December 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29229942/a-neuronal-signature-of-accurate-imitative-learning-in-wild-caught-songbirds-swamp-sparrows-melospiza-georgiana
#20
Dana L Moseley, Narendra R Joshi, Jonathan F Prather, Jeffrey Podos, Luke Remage-Healey
In humans and other animals, behavioural variation in learning has been associated with variation in neural features like morphology and myelination. By contrast, it is essentially unknown whether cognitive performance scales with electrophysiological properties of individual neurons. Birdsong learning offers a rich system to investigate this topic as song acquisition is similar to human language learning. Here, we address the interface between behavioural learning and neurophysiology in a cohort of wild-caught, hand-reared songbirds (swamp sparrows, Melospiza georgiana)...
December 11, 2017: Scientific Reports
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